Rcbtb2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000015054 0.11 0.07 8.8e-09 0.06 0.05 0.05 0.06 2.5e-07 1.7e-06 3.3e-06 6.8e-07
2 Adipose intron excision ratio chr15:48333445:48336229 0.15 0.08 0.0e+00 0.15 0.15 0.14 0.14 6.4e-16 2.4e-16 1.4e-15 1.4e-15
3 Adipose mRNA stability ENSRNOG00000015054 0.03 0.02 6.4e-03 0.01 0.01 0.01 0.01 1.6e-02 1.7e-02 9.1e-03 3.6e-02
4 BLA mRNA stability ENSRNOG00000015054 0.08 0.06 9.5e-03 0.02 0.03 0.01 0.03 2.4e-02 8.5e-03 5.6e-02 1.6e-02
5 Brain mRNA stability ENSRNOG00000015054 0.04 0.04 3.3e-03 0.01 0.02 0.02 0.01 3.1e-02 9.5e-03 9.1e-03 2.6e-02
6 Liver alternative TSS ENSRNOT00000020836 0.19 0.09 0.0e+00 0.15 0.15 0.17 0.15 6.0e-16 4.4e-16 3.9e-18 2.2e-16
7 Liver alternative TSS ENSRNOT00000091000 0.19 0.09 0.0e+00 0.14 0.14 0.16 0.14 2.5e-15 1.6e-15 7.3e-18 1.3e-15
8 Liver gene expression ENSRNOG00000015054 0.17 0.1 1.4e-14 0.11 0.12 0.11 0.12 6.6e-12 7.5e-13 2.7e-12 3.4e-13
9 Liver intron excision ratio chr15:48333400:48336229 0.08 0.08 9.5e-04 0.02 0.01 0.03 0.01 2.7e-03 1.1e-02 4.4e-04 1.3e-02
10 Liver intron excision ratio chr15:48333445:48336229 0.38 0.3 3.4e-10 0.06 0.06 0.07 0.07 2.9e-07 1.2e-07 5.7e-08 1.8e-08
11 Liver intron excision ratio chr15:48355011:48357257 0.1 0.06 2.8e-09 0.08 0.07 0.08 0.07 2.2e-09 4.3e-08 6.1e-09 1.2e-08
12 Liver intron excision ratio chr15:48357396:48358748 0.03 0.03 1.6e-03 0.02 0.01 0.02 0.02 1.9e-03 8.2e-03 4.1e-03 5.0e-03
13 Liver intron excision ratio chr15:48358397:48358748 0.2 0.09 0.0e+00 0.21 0.2 0.2 0.2 1.1e-22 3.0e-22 3.0e-22 3.4e-22
14 Liver mRNA stability ENSRNOG00000015054 0.26 0.1 0.0e+00 0.24 0.26 0.24 0.25 3.2e-26 3.7e-28 7.5e-27 1.9e-27

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.10.31.3-0.6-0.5-0.6-0.6-0.11.1-1.10.4-0.2-0.4-0.2-0.40.5-0.0
BMI without tail0.51.02.80.3-1.60.2-1.20.51.4-1.21.70.3-1.30.30.4-0.41.0
Body weight0.41.54.31.3-0.61.40.50.7-1.01.20.41.4-1.72.11.2-1.41.2
Epididymis fat weight1.53.56.52.2-2.22.6-1.10.7-0.20.42.22.2-1.81.82.0-2.12.5
Glucose1.11.64.2-1.6-0.2-1.8-0.8-0.52.0-1.90.2-1.40.3-0.7-1.51.6-0.9
Heart weight0.10.20.50.5-0.10.40.30.7-0.60.60.2-0.1-0.40.10.6-0.50.2
Left kidney weight1.74.89.43.0-1.32.30.62.1-1.31.41.41.9-2.72.62.9-3.12.3
Right kidney weight3.510.020.44.4-1.63.51.23.1-2.42.61.72.5-3.73.34.4-4.53.0
Tail length1.03.16.42.3-1.21.70.52.1-0.91.11.31.1-2.52.12.1-2.41.7
Length with tail0.52.03.91.8-0.01.81.00.6-1.81.9-0.11.6-1.02.01.4-1.71.1
Length without tail0.51.02.80.01.50.41.2-0.9-1.71.6-1.60.51.20.2-0.20.1-0.6
Liver weight, left0.10.20.9-0.30.7-0.10.4-0.6-0.20.1-0.70.21.0-0.0-0.30.4-0.3
Liver weight, right0.20.40.9-0.80.5-0.90.3-0.20.3-0.3-0.7-0.70.20.0-0.90.9-0.7
Parametrial fat weight0.71.33.40.2-1.81.0-1.8-0.91.4-1.31.91.1-0.20.20.1-0.21.3
Retroperitoneal fat weight0.41.32.90.7-1.51.7-1.4-1.00.4-0.31.61.7-0.20.50.5-0.71.5
Intraocular pressure0.40.61.60.4-1.10.7-0.6-0.10.6-0.50.81.2-0.61.30.6-0.51.1
Extensor digitorum longus weight3.915.829.7-4.25.2-5.02.7-0.8-0.60.1-5.0-4.73.8-4.1-4.24.2-5.4
Soleus weight3.39.615.4-3.73.4-3.81.0-1.70.6-1.0-3.2-3.33.6-3.5-3.73.8-3.9
Tibialis anterior weight2.38.115.6-2.73.9-3.52.4-0.4-0.90.6-3.8-3.52.5-2.5-2.82.8-3.9
Tibia length6.518.332.35.4-2.54.91.33.5-3.74.22.03.9-5.05.75.4-5.44.2
Number of licking bursts0.50.61.40.1-1.20.7-1.0-0.80.8-0.71.01.1-0.40.80.3-0.11.0
Food consumed during 24 hour testing period0.50.72.70.90.0-0.00.91.6-0.60.6-0.0-0.5-1.20.81.0-0.90.1
Times rat made contact with spout1.51.84.10.9-2.01.0-1.10.31.0-0.81.81.2-1.71.71.0-0.91.7
Mean time between licks in bursts0.10.20.30.3-0.50.0-0.30.60.5-0.60.60.0-0.30.10.4-0.30.4
Mean num. licks in bursts0.10.10.70.2-0.1-0.10.20.9-0.10.20.2-0.4-0.70.40.1-0.20.0
Std. dev. time between licks in bursts2.12.55.52.2-0.31.51.12.2-1.41.40.50.9-1.51.62.3-2.21.2
Water consumed over 24 hours0.20.20.60.20.2-0.40.60.80.0-0.0-0.2-0.3-0.70.60.4-0.2-0.1
Indifference point 0 sec3.96.212.53.3-1.62.90.62.0-1.72.11.52.2-2.83.53.1-3.12.6
Indifference point AUC1.61.94.5-1.70.6-1.9-0.3-0.30.9-0.9-0.6-2.11.2-1.6-1.91.7-1.6
Indifference point function ln k1.62.24.42.0-0.81.90.30.6-0.80.80.82.1-1.51.72.0-2.01.7
Indifference point function log k1.62.24.42.0-0.81.90.30.6-0.80.80.82.1-1.51.72.0-2.01.7
Delay discounting total patch changes 0 sec3.65.812.63.1-1.52.80.71.9-1.62.01.32.2-2.73.53.0-3.02.5
Delay discounting total patch changes 12 sec0.91.23.51.3-0.40.60.81.6-0.91.10.20.2-1.31.91.2-1.20.7
Delay discounting total patch changes 18 sec0.30.41.10.3-1.00.3-0.6-0.10.8-0.60.80.7-0.61.10.2-0.20.8
Delay discounting total patch changes 24 sec1.31.64.51.4-0.51.00.81.5-1.11.30.30.7-1.82.11.4-1.41.0
Delay discounting total patch changes 6 sec1.11.73.51.1-1.91.7-1.2-0.30.5-0.21.71.8-1.01.70.9-1.01.8
Delay discounting time to switch 0 sec0.00.00.10.10.20.20.2-0.1-0.20.1-0.20.40.0-0.10.3-0.10.1
Delay discounting water rate 0 sec0.50.83.20.9-0.60.90.30.7-0.71.00.40.7-1.31.80.7-0.80.8
Delay discounting water rate 12 sec0.10.10.60.1-0.10.3-0.3-0.70.3-0.30.00.80.50.0-0.0-0.00.3
Delay discounting water rate 18 sec0.20.20.8-0.3-0.40.3-0.7-0.90.5-0.40.40.40.3-0.3-0.30.40.2
Delay discounting water rate 24 sec0.71.02.4-0.6-1.20.4-1.5-1.51.5-1.31.01.10.30.4-0.60.60.8
Delay discounting water rate 6 sec0.20.31.0-0.40.8-0.60.70.1-0.40.4-1.0-0.3-0.00.1-0.40.5-0.6
Locomotor activity3.45.415.61.03.0-0.53.92.4-3.83.6-3.1-1.1-0.60.91.0-1.0-1.5
Locomotor testing distance2.64.312.01.61.90.53.22.2-3.53.4-2.0-0.0-1.31.71.6-1.6-0.4
Locomotor testing rearing3.25.012.42.11.70.83.32.7-3.53.5-1.80.2-1.72.12.0-2.1-0.1
Light reinforcement 11.32.36.00.9-2.41.8-1.8-0.40.8-0.52.41.7-1.31.31.0-0.92.0
Light reinforcement 21.72.27.3-0.6-2.10.5-2.7-1.82.1-1.92.10.70.2-0.7-0.70.71.0
Reaction time number correct1.92.74.6-2.10.5-1.7-1.0-1.81.8-1.9-0.5-1.02.0-2.0-2.02.2-1.3
Reaction time mean minus median1.21.54.81.01.30.52.00.9-2.22.1-1.40.1-0.31.00.9-1.0-0.2
Reaction time mean minus median AUC0.60.82.80.70.60.51.20.7-1.71.7-0.70.1-0.40.80.7-0.70.0
Reaction time num false alarms0.10.10.40.4-0.10.10.20.6-0.20.30.3-0.5-0.30.00.4-0.4-0.0
Reaction time num false alarms AUC0.10.20.50.6-0.40.20.00.7-0.10.10.7-0.5-0.50.10.6-0.50.2
Reaction time trials correct on left1.92.74.6-2.10.5-1.7-1.0-1.81.8-1.9-0.5-1.02.0-2.0-2.02.2-1.3
Reaction time trials on left1.82.64.4-2.00.4-1.6-1.0-1.81.8-1.9-0.4-0.92.0-1.9-2.02.1-1.2
Reaction time mean1.01.44.41.01.20.31.81.4-2.12.0-1.1-0.3-0.40.30.9-1.0-0.4
Reaction time mean AUC1.21.54.70.81.50.12.01.4-2.22.0-1.4-0.5-0.20.10.8-0.9-0.6
Median of all reaction times0.60.82.50.80.90.31.31.3-1.61.5-0.7-0.4-0.3-0.00.7-0.9-0.3
Reaction time omissions0.40.51.01.0-0.51.00.00.3-0.40.40.50.9-0.30.90.9-1.00.9
Reaction time false alarm rate0.71.01.81.3-0.81.00.31.2-0.70.90.90.1-1.41.01.3-1.30.8
Reaction time premature initiation rate1.01.35.0-0.8-0.30.2-1.4-2.21.3-1.40.41.21.7-1.0-0.70.80.2
Reaction time premature initiations2.33.29.3-1.9-0.1-0.7-1.9-3.02.1-2.30.20.52.7-2.0-1.71.9-0.5
Std. dev. reaction times0.81.13.80.71.20.31.70.8-2.01.9-1.3-0.10.00.50.6-0.7-0.4
Reaction time trials completed1.82.64.4-2.00.4-1.6-1.0-1.81.8-1.9-0.4-0.92.0-1.9-2.02.1-1.2
Reaction time trials AUC1.92.74.6-2.10.5-1.7-1.0-1.81.8-1.9-0.5-1.02.0-2.0-2.02.2-1.3
Social response proportion3.03.26.8-1.8-0.1-1.3-1.8-2.32.4-2.60.2-0.52.4-2.3-1.81.9-0.8
Social responses0.70.92.8-0.3-0.70.0-1.4-1.31.5-1.70.90.41.2-1.0-0.10.30.4
Social time0.60.81.61.2-0.00.90.71.1-1.21.30.20.2-0.80.71.1-1.10.5
Conditioned locomotion0.40.41.3-0.5-0.3-0.0-0.9-1.10.8-0.80.40.10.7-0.9-0.60.5-0.0
Cocaine response after cond. corrected2.42.75.2-2.00.5-1.3-1.2-2.31.7-1.8-0.4-0.62.2-2.2-2.02.0-1.1
Cocaine response after cond. not corrected0.70.81.5-1.10.1-0.7-0.8-1.10.9-1.0-0.0-0.51.1-1.2-1.11.1-0.6
Cocaine response before conditioning3.03.77.42.3-0.91.81.02.6-1.82.00.80.8-2.72.62.3-2.31.5
Saline control response0.50.72.80.6-0.50.60.30.4-0.10.20.21.2-1.41.70.8-0.60.9
Condit. Reinf. active minus inactive responses0.30.41.10.6-0.81.0-0.5-0.2-0.10.20.81.0-0.20.60.6-0.60.9
Condit. Reinf. active-inactive response ratio0.10.10.20.1-0.40.3-0.30.3-0.20.30.4-0.2-0.2-0.0-0.0-0.10.2
Condit. Reinf. active responses0.60.81.50.9-1.11.1-0.50.20.10.01.11.1-0.71.10.9-0.91.2
Condit. Reinf. inactive responses1.01.22.91.1-1.21.2-0.30.20.2-0.11.11.5-1.11.71.3-1.11.5
Condit. Reinf. lever presses2.02.85.62.2-0.41.21.32.4-1.51.60.40.6-2.12.02.3-2.21.1
Condit. Reinf. lever reinforcers received0.71.01.91.1-1.11.1-0.30.7-0.10.21.11.0-1.11.41.2-1.11.3
Pavlov. Cond. lever latency1.31.74.6-1.5-0.4-0.5-1.6-2.11.7-1.70.40.11.5-1.3-1.51.5-0.2
Pavlov. Cond. magazine entry latency1.72.05.71.60.30.31.62.4-1.51.6-0.3-0.4-2.11.41.5-1.60.3
Pavlov. Cond. change in total contacts0.81.13.30.11.7-1.01.81.1-1.00.8-1.6-1.10.2-0.50.2-0.1-1.2
Pavlov. Cond. index score1.62.15.71.40.90.02.22.4-1.91.9-0.9-0.6-1.61.11.4-1.4-0.2
Pavlov. Cond. latency score1.82.35.91.60.90.22.22.4-2.02.0-0.8-0.4-1.61.21.6-1.6-0.0
Pavlov. Cond. lever contacts1.82.67.01.70.90.22.32.6-2.12.0-0.9-0.4-1.71.51.7-1.7-0.0
Pavlov. Cond. magazine entry number1.11.44.9-1.50.0-0.2-1.3-2.20.9-1.0-0.00.41.9-1.1-1.41.5-0.3
Pavlov. Cond. intertrial magazine entries2.22.96.61.4-2.62.0-1.60.10.7-0.42.51.9-1.61.81.4-1.42.3
Pavlov. Cond. lever-magazine prob. diff.1.41.85.01.30.9-0.02.02.2-1.81.7-0.9-0.7-1.40.91.2-1.3-0.3
Pavlov. Cond. response bias2.02.88.41.61.0-0.12.52.9-2.02.0-1.1-0.7-1.91.61.6-1.6-0.2
Conditioned reinforcement - actives1.41.43.4-1.1-0.7-0.6-1.6-1.51.8-1.80.8-0.21.1-1.2-1.01.1-0.1
Conditioned reinforcement - inactives1.41.62.51.5-1.31.5-0.30.7-0.30.41.31.3-1.61.61.6-1.51.5
Conditioned locomotion0.10.10.30.30.0-0.30.30.60.1-0.20.2-0.6-0.20.00.4-0.3-0.1
Intermittent access intake day 1-15 change1.71.73.81.2-1.61.8-0.9-0.20.2-0.01.61.9-1.11.51.1-1.21.9
Intermittent access intake escalation1.31.23.10.7-1.51.4-1.0-0.50.5-0.31.31.8-0.91.30.7-0.81.6
Intermittent access intake escalation 20.50.50.90.4-0.90.6-0.8-0.40.9-0.80.91.0-0.20.30.4-0.40.9
Intermitt. access day 1 inactive lever presses0.80.93.70.6-1.01.3-0.7-1.00.4-0.30.81.9-0.11.00.6-0.71.3
Intermitt. access day 15 inactive lever presses0.80.92.11.1-0.71.20.00.3-0.20.30.61.4-1.01.41.2-1.11.2
Intermitt. access escalation Index0.50.50.9-0.80.8-0.90.4-0.2-0.20.2-1.0-0.70.4-0.4-0.90.9-0.9
Intermittent access day 1 total infusions0.50.62.70.6-1.00.5-0.20.40.10.20.70.5-1.31.60.6-0.50.9
Intermittent access day 15 total infusions1.31.43.20.9-1.61.4-0.9-0.30.5-0.21.41.7-1.21.80.8-0.81.7
Intermittent access terminal intake (last 3 days)0.60.71.60.4-1.20.8-0.8-0.30.6-0.31.01.0-0.81.20.4-0.41.1
Intermittent access total infusions1.11.33.10.7-1.61.2-0.9-0.20.6-0.21.31.4-1.31.80.7-0.71.5
Intermittent access day 1 locomotion1.71.74.71.5-1.41.5-0.20.5-0.10.41.11.4-1.72.21.5-1.41.6
Intermittent access day 15 total locomotion0.80.92.00.4-1.40.8-1.1-0.61.1-0.91.31.1-0.60.90.4-0.41.2
Intermittent access total locomotion1.11.33.41.1-1.31.1-0.40.30.4-0.11.21.3-1.51.81.1-1.11.4
Intermittent access standard deviation0.30.42.00.1-0.60.7-0.2-0.3-0.10.30.21.0-0.61.40.1-0.10.7
Cocaine induced anxiety1.72.05.50.91.9-0.22.31.5-2.32.1-1.8-0.5-0.20.21.0-0.9-0.9
Post-drug Anxiety0.60.71.71.2-0.31.30.00.0-0.50.40.51.3-0.00.41.2-1.20.9
Baseline Anxiety1.51.64.00.6-2.01.4-1.6-0.61.1-0.91.91.5-0.71.00.4-0.61.7
Lifetime Intake0.80.92.80.7-1.41.0-0.6-0.00.3-0.01.11.1-1.31.70.7-0.61.3
Incentive Sensitization - Responses0.90.93.00.4-1.60.6-1.20.20.9-0.61.70.3-1.10.60.4-0.41.0
Incentive Sensitization - Breakpoint1.11.13.60.7-1.80.9-1.20.40.8-0.61.90.5-1.30.90.7-0.71.3
Progressive ratio test 1 active lever presses0.50.62.0-0.6-0.8-0.3-1.0-0.91.4-1.20.60.3-0.10.4-0.50.60.3
Progressive ratio test 1 breakpoint0.80.82.7-0.7-1.0-0.3-1.2-1.11.6-1.50.80.30.00.3-0.60.70.3
Progressive ratio test 1 inactive lever presses2.42.66.20.6-2.31.7-1.8-1.31.5-1.12.02.5-0.91.80.7-0.62.2
Progressive ratio test 2 active lever presses1.31.44.0-0.5-1.80.1-1.9-0.92.0-1.71.70.4-0.40.4-0.50.50.8
Progressive ratio test 2 breakpoint1.11.23.5-0.0-1.90.5-1.6-0.51.6-1.31.80.6-0.90.9-0.00.01.1
Progressive ratio test 2 inactive lever presses1.01.22.50.8-1.40.9-0.70.00.9-0.61.31.4-1.31.60.9-0.81.4
Total sessions with >9 infusions0.30.30.80.3-0.80.4-0.6-0.20.6-0.50.90.4-0.30.30.4-0.40.6
Short access day 1 total inactive lever presses1.92.17.71.3-1.51.5-0.10.9-0.40.91.21.2-2.32.81.3-1.31.6
Short access day 10 total inactive lever presses0.60.71.60.4-1.10.9-0.9-0.60.8-0.61.11.3-0.40.80.5-0.51.2
Short access day 1 total infusions0.20.20.4-0.2-0.60.1-0.6-0.50.6-0.50.50.3-0.20.4-0.10.20.3
Short access day 10 total infusions0.91.03.80.8-0.10.31.01.3-1.01.3-0.20.0-1.71.90.8-0.80.3
Short access total infusions0.70.82.60.8-1.20.9-0.30.30.10.21.00.8-1.41.60.7-0.71.1
Short access day 1 locomotion0.50.51.20.90.50.31.10.8-0.90.9-0.50.2-0.50.71.0-0.90.1
Short access day 10 total locomotion0.91.02.51.4-0.30.70.71.6-0.80.80.50.1-1.30.81.5-1.40.6
Short access total locomotion1.71.73.71.9-0.81.40.41.0-0.60.70.91.2-1.41.61.9-1.91.4
Compulsive drug intake0.90.92.40.80.30.61.11.1-1.41.5-0.50.2-1.01.20.8-0.80.2
One hour access (0.3 mA shock)0.20.21.30.1-0.50.2-0.1-0.10.10.10.20.5-0.81.10.2-0.10.4
One hour access (shock baseline)0.40.40.9-0.9-0.0-0.7-0.5-0.90.9-0.9-0.1-0.20.4-0.2-0.80.9-0.4
Number of responses in last shaping day0.10.10.5-0.20.5-0.50.40.2-0.10.1-0.4-0.70.2-0.4-0.20.3-0.5
Context. condit. distance diff. score2.12.57.9-0.9-2.20.3-2.8-1.82.4-2.22.20.7-0.1-0.6-0.80.91.0
Locomotion velocity, session 11.01.12.4-0.61.6-1.01.20.6-1.10.9-1.5-1.30.7-0.7-0.60.6-1.4
Locomotion distance, session 10.70.93.20.60.8-0.31.51.8-1.21.2-0.8-0.7-0.81.00.5-0.6-0.4
Locomotion velocity, session 20.50.61.90.50.60.21.11.0-1.41.4-0.6-0.2-0.20.70.6-0.5-0.2
Locomotion distance, session 21.92.78.10.81.4-0.52.62.8-2.22.2-1.6-1.1-1.51.50.9-0.8-0.7
Locomotion velocity, session 30.30.30.9-0.5-0.5-0.2-0.9-0.71.0-0.90.6-0.10.4-0.5-0.50.50.0
Locomotion distance, session 30.50.51.5-0.3-1.10.3-1.2-0.71.2-1.11.10.5-0.2-0.1-0.10.20.6
Stereotopy head waving bouts, day 30.60.72.0-0.81.0-0.90.3-0.60.3-0.5-0.9-0.51.4-1.1-0.70.8-0.9
Stereotopy head waving duration, day 30.70.92.3-0.61.5-1.01.20.2-0.70.5-1.5-1.00.8-0.7-0.60.6-1.2
Locomotion velocity, session 74.24.613.7-0.2-3.41.2-3.7-1.73.0-2.73.41.6-0.60.0-0.10.22.1
Locomotion distance, session 72.83.59.9-0.5-2.70.4-3.1-1.63.1-2.92.71.0-0.4-0.3-0.40.51.5
Stereotopy head waving bouts, day 70.60.62.00.50.70.21.21.1-1.41.4-0.8-0.2-0.20.60.5-0.5-0.2
Stereotopy head waving duration, day 70.40.41.40.01.00.00.90.2-1.21.1-1.0-0.20.6-0.00.0-0.0-0.5
Locomotion velocity, session 80.10.10.4-0.3-0.7-0.0-0.6-0.00.5-0.40.50.1-0.40.2-0.20.30.3
Locomotion distance, session 80.50.73.20.5-1.10.3-0.31.20.3-0.11.00.1-1.81.30.7-0.50.7
Degree of sensitization distance1.21.23.6-0.4-1.5-0.0-1.8-0.81.9-1.81.40.40.0-0.3-0.40.40.7
Degree of sensitization stereotypy0.40.41.40.50.20.60.60.6-1.11.2-0.30.2-0.30.80.4-0.50.2
Condit. Reinf. active minus inactive responses0.70.81.71.30.11.00.70.6-1.01.0-0.21.0-0.31.11.0-1.20.7
Condit. Reinf. active-inactive response ratio0.40.41.6-0.30.7-0.4-0.0-0.70.3-0.5-0.5-0.11.3-1.2-0.50.5-0.5
Condit. Reinf. active responses2.12.65.52.2-0.61.80.91.3-1.51.70.41.6-1.32.31.9-2.11.5
Condit. Reinf. inactive responses4.35.112.12.7-1.12.31.02.1-2.02.30.81.8-2.83.52.7-2.82.0
Incentive salience index mean3.54.28.22.9-0.72.41.01.7-2.02.10.62.0-1.82.62.6-2.81.9
Condit. Reinf. lever presses5.87.814.13.8-1.43.21.02.2-2.22.41.32.7-2.93.63.6-3.72.8
Time in familiar zone, hab. session 10.50.51.50.6-1.10.5-0.60.50.3-0.21.00.4-1.20.60.6-0.60.8
Time in novel zone, hab. session 13.83.78.6-2.41.6-1.9-0.1-1.90.9-1.1-1.6-1.42.9-2.1-2.52.4-2.0
Total zone transitions, hab. session 10.40.51.4-0.01.0-0.81.21.0-0.70.6-1.0-1.0-0.10.1-0.10.0-0.8
Total locomotion distance, hab. session 10.81.23.30.90.70.11.51.8-1.61.6-0.8-0.5-0.71.00.8-0.9-0.2
Locomotion velocity, hab. session 12.02.97.51.70.80.62.22.7-2.52.6-0.9-0.3-1.71.81.5-1.70.1
Time in familiar zone, hab. session 21.31.32.6-1.60.6-1.1-0.5-1.40.7-0.8-0.6-0.91.2-1.5-1.61.6-1.1
Time in novel zone, hab. session 20.20.20.90.40.10.10.50.9-0.40.4-0.1-0.0-0.40.70.5-0.40.1
Total zone transitions, hab. session 21.21.54.70.21.8-0.62.21.2-1.71.6-1.9-0.7-0.00.50.2-0.2-1.0
Total locomotion distance, hab. session 20.71.02.90.31.3-0.31.71.2-1.41.4-1.4-0.5-0.20.80.3-0.3-0.6
Locomotion velocity, hab. session 21.11.54.50.41.6-0.52.11.6-1.81.7-1.7-0.8-0.30.80.3-0.4-0.9
Novel to familiar place preference ratio0.80.93.40.9-0.70.70.20.9-0.20.30.51.0-1.11.81.2-0.91.0
Novelty place preference1.01.03.71.0-0.80.90.20.9-0.30.50.51.1-1.21.91.2-1.01.1
Time in novel zone, NPP test0.70.72.90.8-0.60.70.31.0-0.30.50.40.8-1.01.71.0-0.80.9
Total zone transitions, NPP test0.60.81.80.80.40.41.21.1-1.31.3-0.60.1-0.81.30.8-0.80.1
Total locomotion distance, NPP test1.21.64.31.4-0.21.01.11.6-1.41.50.00.6-1.52.11.4-1.40.8
Locomotion velocity, NPP test1.31.85.21.6-0.41.20.91.4-1.21.40.31.0-1.62.31.6-1.61.1
Pavlov. Cond. lever latency2.63.36.2-2.31.4-2.3-0.1-0.91.0-1.2-1.2-2.21.9-2.5-2.32.2-2.2
Pavlov. Cond. magazine entry latency0.70.91.81.0-1.21.2-0.60.10.1-0.01.01.3-0.91.11.0-1.01.3
Pavlov. Cond. change in total contacts1.21.33.61.5-0.51.20.50.8-0.80.90.31.3-1.21.91.4-1.31.2
Pavlov. Cond. index score2.32.95.42.1-1.42.1-0.01.0-0.81.11.12.0-2.02.32.0-2.02.0
Pavlov. Cond. latency score2.93.66.62.4-1.62.4-0.11.0-0.81.11.42.3-2.12.62.3-2.32.3
Pavlov. Cond. lever contacts2.93.45.92.3-1.42.30.10.9-1.21.41.12.2-2.02.42.2-2.22.1
Pavlov. Cond. magazine entry number0.20.30.6-0.60.5-0.50.1-0.40.1-0.2-0.4-0.50.8-0.8-0.50.5-0.6
Pavlov. Cond. intertrial magazine entries1.41.63.21.8-0.31.50.70.9-1.51.50.41.1-1.11.41.6-1.71.1
Pavlov. Cond. lever-magazine prob. diff.1.92.44.61.9-1.11.80.21.0-0.91.10.91.7-1.92.11.8-1.81.7
Pavlov. Cond. response bias0.70.91.51.2-0.71.2-0.10.3-0.50.60.61.2-1.01.11.1-1.11.1
Bone: apparent density0.40.72.90.6-0.2-0.10.71.7-0.60.70.1-0.6-1.61.00.6-0.60.1
Bone surface0.50.82.70.70.2-0.21.11.7-0.80.9-0.3-0.7-1.51.10.8-0.7-0.1
Bone volume0.50.93.50.40.3-0.51.21.9-0.81.0-0.4-1.1-1.61.10.5-0.4-0.4
Bone: connectivity density0.60.91.51.1-1.01.2-0.20.5-0.30.40.91.1-1.21.21.1-1.11.2
Bone: cortical apparent density2.02.67.3-1.4-0.6-0.4-2.0-2.72.3-2.40.70.61.9-1.7-1.51.40.0
Bone: cortical area0.10.20.8-0.00.1-0.70.50.90.2-0.2-0.1-0.9-0.60.20.2-0.0-0.3
Bone: cortical porosity2.32.54.71.80.21.21.62.1-2.12.2-0.20.5-2.01.81.8-1.80.7
Bone: cortical porosity2.02.14.81.60.30.81.62.2-1.81.9-0.30.1-2.01.61.6-1.60.4
Bone: cortical thickness0.10.20.60.3-0.60.3-0.20.00.4-0.30.50.5-0.60.80.5-0.30.6
Bone: cortical thickness0.40.51.6-0.6-0.8-0.2-1.0-0.71.3-1.20.70.10.20.1-0.40.60.2
Bone: cortical tissue density2.12.87.8-1.5-0.5-0.5-2.0-2.82.3-2.40.60.52.0-1.8-1.61.4-0.0
Bone: elastic displacement0.30.41.10.50.70.11.00.5-0.80.8-0.90.3-0.20.90.4-0.4-0.1
Bone: elastic work1.52.04.91.01.0-0.02.22.2-1.91.9-1.2-0.4-1.51.71.1-1.0-0.3
Bone: endosteal estimation0.30.72.70.10.7-1.11.11.4-0.30.2-0.5-1.6-0.5-0.20.1-0.1-0.9
Bone: endosteal perimeter0.30.72.50.10.9-1.01.11.4-0.50.3-0.6-1.6-0.0-0.60.1-0.2-1.0
Bone: final force0.60.92.81.0-0.90.60.11.10.10.00.90.5-1.71.51.2-1.11.0
Bone: final moment0.61.02.91.1-0.60.50.51.3-0.20.30.60.4-1.71.61.3-1.20.8
Bone: marrow area0.30.62.40.20.7-0.91.11.5-0.30.3-0.5-1.5-0.7-0.10.2-0.3-0.8
Bone: maximum diameter0.40.82.8-0.90.5-1.40.10.30.6-0.6-0.2-1.70.5-1.1-0.80.8-1.1
Bone: maximum force0.50.83.10.7-0.1-0.21.01.8-0.30.40.0-0.5-1.71.30.9-0.80.2
Bone: maximum moment0.61.14.30.90.1-0.21.32.1-0.60.6-0.2-0.5-1.81.51.1-1.00.1
Bone: minimum diameter0.40.83.10.60.5-0.71.41.8-0.50.5-0.4-1.1-1.00.80.7-0.7-0.4
Bone: periosteal estimation0.20.52.3-0.00.5-1.10.81.20.1-0.1-0.3-1.5-0.5-0.20.1-0.0-0.7
Bone: periosteal perimeter0.20.31.4-0.20.3-1.00.40.70.4-0.4-0.1-1.2-0.0-0.3-0.10.1-0.6
Bone: post-yield work0.40.51.7-0.1-1.1-0.2-0.90.31.3-1.21.1-0.2-0.90.30.00.10.5
Bone: stiffness0.40.61.90.9-0.60.40.31.1-0.10.20.60.1-1.41.01.0-1.00.6
Bone: tissue strength0.50.51.81.0-0.00.30.71.4-0.60.50.10.1-0.90.61.0-1.00.4
Bone: trabecular number0.50.82.61.0-0.80.80.11.3-0.60.80.80.2-1.61.11.0-1.00.8
Bone: trabecular spacing0.60.71.9-0.91.1-0.80.3-0.60.1-0.3-0.9-0.71.4-1.2-0.90.9-1.0
Bone: trabecular thickness0.91.04.20.8-0.70.60.41.5-0.70.90.40.1-2.11.70.9-0.80.7
Bone: trabecular tissue density0.81.12.0-1.01.3-1.30.7-0.20.1-0.3-1.2-1.31.0-1.3-1.01.0-1.4
Breakpoint value in progressive ratio session0.70.81.9-1.40.8-0.90.1-1.20.2-0.2-1.2-0.10.8-0.0-1.31.3-0.8
Distance traveled before self-admin1.51.63.9-0.61.9-1.51.70.8-0.90.8-2.0-1.60.4-0.6-0.60.6-1.6
Distance traveled after self-admin2.73.05.9-2.01.4-2.3-0.0-1.00.9-1.1-1.3-2.11.9-2.4-2.12.1-2.0
Delta time in closed arm before/after self-admin0.20.20.70.7-0.10.20.20.9-0.50.40.3-0.4-0.4-0.20.6-0.60.1
Delta time in open arm before/after self-admin0.10.10.20.1-0.30.0-0.20.20.5-0.40.40.1-0.10.20.2-0.20.2
Diff in mean of infusions in LGA sessions1.31.43.7-1.90.9-0.9-0.2-1.90.3-0.3-1.30.11.4-0.4-1.81.8-0.9
Extinction: sum of active levers before priming0.40.41.20.2-0.90.6-0.50.10.2-0.00.70.8-1.01.10.3-0.20.8
Active lever presses in extinction session 60.50.51.00.0-1.00.6-1.0-0.70.9-0.70.90.9-0.30.5-0.1-0.00.8
Delta distance traveled before/after self-admin2.62.84.3-2.0-0.1-1.4-1.6-2.02.0-2.10.2-0.92.0-2.1-2.12.0-0.9
Delta ambulatory time before/after self-admin1.41.52.5-1.4-0.0-1.0-1.1-1.61.5-1.60.1-0.61.4-1.5-1.51.5-0.7
Time in closed arm before self-admin0.10.10.4-0.0-0.0-0.3-0.20.20.4-0.50.3-0.40.2-0.6-0.1-0.1-0.2
Time in closed arm after self-admin0.10.10.3-0.10.3-0.30.2-0.0-0.0-0.1-0.2-0.30.3-0.6-0.00.1-0.3
Time in open arm before self-admin0.50.51.1-1.00.8-0.80.2-0.5-0.20.3-1.0-0.60.7-0.5-0.91.1-0.9
Time in open arm after self-admin0.10.10.3-0.30.2-0.50.10.30.1-0.1-0.2-0.50.1-0.4-0.20.3-0.4
Sum of active levers in priming session hrs 5-62.52.44.4-2.00.1-1.2-1.4-1.81.5-1.5-0.0-1.01.9-2.0-2.12.1-1.1
Time to tail flick, vehicle, before self-admin1.91.94.81.1-1.62.0-0.6-0.1-0.40.81.31.9-1.42.21.0-1.11.8
Time to tail flick, vehicle, after self-admin1.81.96.1-1.90.0-0.7-1.2-2.51.4-1.4-0.30.11.7-0.9-1.91.8-0.6
Time to tail flick, test, before self-admin0.80.83.21.0-0.00.10.91.8-0.70.80.1-0.4-1.40.81.0-1.00.2
Time to tail flick, test, after self-admin1.81.84.91.1-2.11.7-1.7-0.30.8-0.72.21.4-0.50.61.0-1.01.8
Delta time to tail flick, vehicle, before/after SA1.91.93.2-1.80.4-1.3-0.9-1.81.6-1.6-0.5-0.51.7-1.3-1.81.8-0.9
Delta time to tail flick, test, before/after SA1.51.34.1-0.3-1.50.7-2.0-1.41.4-1.41.60.70.8-0.7-0.30.30.9
Ambulatory time before self-admin0.90.92.4-0.41.4-1.01.40.9-1.00.9-1.5-1.2-0.20.1-0.40.4-1.1
Ambulatory time after self-admin2.32.54.8-1.71.8-2.20.6-0.60.3-0.5-1.8-1.91.6-1.8-1.81.8-2.0
Total heroin consumption0.60.82.1-0.91.2-0.70.8-0.2-0.90.9-1.4-0.60.40.0-0.90.9-1.0
Area under the delay curve0.60.72.30.70.2-0.11.01.5-0.91.0-0.3-0.6-1.20.90.7-0.7-0.1
Delay disc. indifference point, 0s delay0.70.82.10.80.80.21.31.2-1.41.3-0.7-0.1-0.40.20.9-0.8-0.1
Delay disc. indifference point, 16s delay0.40.40.90.20.4-0.30.90.9-0.80.9-0.5-0.6-0.80.70.1-0.2-0.3
Delay disc. indifference point, 2s delay1.11.23.1-0.21.6-1.21.41.3-1.10.8-1.3-1.80.4-1.1-0.20.2-1.4
Delay disc. indifference point, 24s delay0.10.10.5-0.20.2-0.50.20.3-0.00.1-0.2-0.7-0.2-0.1-0.30.2-0.4
Delay disc. indifference point, 4s delay0.40.41.3-0.20.8-0.80.70.7-0.40.3-0.6-1.10.3-0.5-0.30.2-0.9
Delay disc. indifference point, 8s delay0.60.61.80.9-0.50.50.30.9-0.30.50.40.3-1.41.30.9-0.90.7
Delay discount exponential model param0.60.62.3-0.7-0.20.2-1.0-1.50.8-0.90.20.71.1-0.8-0.60.70.1
Delay discount hyperbolic model param0.70.72.5-0.5-0.60.5-1.2-1.61.0-1.00.61.10.9-0.4-0.40.50.5
Fecal boli incidents, locomotor time 10.91.02.40.10.8-0.41.51.2-1.41.5-1.1-0.7-1.11.20.2-0.1-0.5
Change in fecal boli incidents, locomotor task0.70.72.9-0.40.3-0.4-0.6-0.91.0-1.3-0.10.11.7-1.4-0.40.5-0.3
Time >=10cm from walls, locomotor time 10.90.91.81.3-0.41.20.30.5-0.91.00.40.9-0.81.01.3-1.30.9
Bouts of movement, locomotor time 10.70.82.4-1.10.5-0.2-0.5-1.6-0.10.0-0.6-0.11.4-1.1-1.21.2-0.7
Total resting periods, locomotor time 11.01.12.8-1.30.6-0.6-0.6-1.70.3-0.3-0.6-0.31.6-1.3-1.41.4-0.9
Rest time, locomotor task time 11.41.63.2-1.21.6-1.40.8-0.2-0.50.4-1.5-1.61.1-1.4-1.41.3-1.8
Distance moved, locomotor task time 11.11.22.40.9-1.51.4-1.1-0.40.6-0.51.51.5-0.30.70.9-1.01.6
Vertical activity count, locomotor time 10.10.10.5-0.10.7-0.20.6-0.2-0.30.2-0.7-0.10.4-0.1-0.1-0.0-0.3
Time >=10cm from walls, locomotor time 20.80.92.1-0.61.4-1.10.9-0.0-0.40.2-1.4-1.11.0-0.9-0.80.6-1.3
Bouts of movement, locomotor time 21.21.33.0-1.70.7-1.0-0.3-1.50.4-0.4-0.9-0.51.4-0.8-1.71.7-1.1
Total resting periods, locomotor time 21.01.12.9-1.60.7-1.0-0.3-1.30.3-0.3-0.9-0.61.1-0.6-1.71.6-1.0
Rest time, locomotor task time 20.50.61.6-1.20.4-1.1-0.0-0.30.4-0.2-0.7-1.00.1-0.2-1.31.2-0.9
Distance moved, locomotor task time 20.81.02.01.4-0.71.40.00.4-0.50.60.71.2-0.71.01.3-1.41.2
Vertical activity count, locomotor time 20.70.82.2-0.51.5-0.91.30.3-0.80.7-1.4-1.00.5-0.6-0.40.4-1.2
Weight adjusted by age0.50.61.7-0.21.3-0.40.8-0.1-0.70.4-0.9-0.61.3-1.2-0.30.0-0.9
Seeking ratio, delayed vs. immediate footshock0.40.41.30.8-0.10.9-0.2-0.3-0.0-0.20.41.10.7-0.30.8-0.80.7
Locomotion in novel chamber0.91.12.80.60.3-0.01.41.7-1.31.5-0.6-0.6-1.61.40.5-0.7-0.1
Locomotion in novel chamber post-restriction0.40.51.8-0.80.3-1.10.00.60.5-0.5-0.1-1.3-0.1-0.6-0.80.6-0.8
Progressive ratio0.91.02.2-1.4-0.1-0.9-1.0-1.41.3-1.3-0.0-0.20.8-0.7-1.51.3-0.5
Food seeking constrained by brief footshock6.88.315.9-4.01.3-2.7-1.5-3.92.3-2.5-1.5-1.33.7-3.0-4.03.8-2.4
Seeking ratio, punishment vs. effort0.30.41.4-0.60.6-0.5-0.0-0.40.1-0.3-0.4-0.61.2-1.2-0.50.6-0.7
Run reversals in cocaine runway, females0.20.20.50.1-0.6-0.2-0.50.50.5-0.40.7-0.7-0.6-0.2-0.0-0.20.1
Run reversals in cocaine runway, males0.80.81.9-0.10.8-1.11.41.1-0.40.5-1.2-0.9-1.01.0-0.20.1-0.7
Latency to leave start box in cocaine runway1.01.12.2-1.01.5-1.40.8-0.30.1-0.4-1.4-0.91.3-1.2-0.91.0-1.4
Latency to leave start box in cocaine runway, F0.50.51.3-0.81.1-0.90.6-0.30.1-0.2-1.1-0.50.9-0.6-0.60.7-0.9
Latency to leave start box in cocaine runway, M0.10.10.30.00.4-0.60.40.40.1-0.2-0.4-0.4-0.2-0.20.00.1-0.4
Cd content in liver0.20.30.6-0.1-0.60.3-0.7-0.80.7-0.70.50.80.20.0-0.00.10.5
Co content in liver4.65.49.3-3.01.5-3.0-0.4-1.61.9-2.1-1.3-2.42.2-2.9-2.93.1-2.5
Cu content in liver1.31.63.4-1.41.2-1.60.2-1.00.9-1.1-1.2-0.81.8-1.3-1.31.4-1.3
Fe content in liver0.30.41.00.6-0.80.7-0.6-0.20.4-0.41.00.70.20.30.7-0.70.8
K content in liver0.50.51.40.6-1.20.9-0.9-0.40.2-0.11.20.6-0.40.30.5-0.61.0
Mg content in liver0.20.20.3-0.3-0.4-0.3-0.6-0.40.6-0.50.5-0.50.3-0.5-0.40.3-0.1
Mn content in liver0.20.20.7-0.3-0.2-0.7-0.40.20.7-0.70.3-0.8-0.1-0.7-0.30.4-0.3
Na content in liver3.63.810.61.71.60.52.92.6-3.33.2-1.5-0.6-1.21.21.7-1.7-0.4
Rb content in liver0.50.61.4-0.1-0.80.6-1.2-1.20.9-0.90.81.10.5-0.1-0.10.10.7
Se content in liver1.31.54.80.51.8-0.52.21.4-1.81.6-1.7-0.80.10.10.6-0.5-1.0
Sr content in liver0.20.20.8-0.20.5-0.80.50.50.2-0.3-0.4-0.90.1-0.3-0.20.1-0.6
Zn content in liver1.31.44.60.81.5-0.22.21.1-1.81.7-1.5-0.5-0.40.60.8-0.7-0.7