Slc13a5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000014870 0.42 0.15 1.7e-16 0.19 0.22 0.21 0.21 2.8e-10 2.8e-12 1.6e-11 1.2e-11
2 BLA mRNA stability ENSRNOG00000014870 0.09 0.07 3.1e-03 0.04 0.02 0.02 0.03 4.2e-03 2.1e-02 2.5e-02 1.1e-02
3 Brain gene expression ENSRNOG00000014870 0.31 0.14 0.0e+00 0.22 0.24 0.23 0.24 3.1e-20 5.7e-22 2.5e-21 7.9e-22
4 Brain mRNA stability ENSRNOG00000014870 0.09 0.06 1.2e-08 0.1 0.09 0.08 0.09 2.3e-09 4.7e-09 4.5e-08 5.2e-09
5 IL gene expression ENSRNOG00000014870 0.16 0.11 8.2e-03 0.04 0.09 0.08 0.07 3.4e-02 3.7e-03 6.4e-03 1.1e-02
6 LHb gene expression ENSRNOG00000014870 0.42 0.21 2.0e-06 0.28 0.26 0.24 0.26 2.6e-07 9.0e-07 1.9e-06 7.4e-07
7 Liver gene expression ENSRNOG00000014870 0.37 0.17 0.0e+00 0.22 0.21 0.19 0.21 1.6e-23 1.8e-22 5.1e-21 1.0e-22
8 NAcc gene expression ENSRNOG00000014870 0.1 0.06 3.3e-06 0.06 0.06 0.06 0.06 3.2e-05 4.7e-05 4.4e-05 6.2e-05
9 PL gene expression ENSRNOG00000014870 0.09 0.06 1.6e-05 0.05 0.05 0.04 0.04 7.1e-05 1.9e-04 7.0e-04 6.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail0.10.31.00.60.40.60.40.00.5-1.00.60.5
BMI without tail0.40.81.10.90.90.90.80.30.9-1.01.10.9
Body weight1.77.49.12.92.72.92.72.43.0-1.53.03.0
Epididymis fat weight1.73.99.71.92.11.92.00.21.4-3.12.41.5
Glucose3.55.37.6-2.4-2.4-2.2-2.3-2.3-2.70.9-2.2-2.8
Heart weight0.20.31.40.40.50.40.6-0.30.1-1.20.60.1
Left kidney weight0.10.20.5-0.5-0.6-0.7-0.6-0.60.0-0.2-0.5-0.0
Right kidney weight0.10.20.4-0.4-0.4-0.6-0.5-0.40.1-0.1-0.40.1
Tail length3.410.312.83.43.53.33.42.73.5-1.83.63.4
Length with tail2.38.511.33.13.02.93.02.83.4-1.03.13.3
Length without tail1.73.85.12.11.91.92.11.82.2-1.01.92.2
Liver weight, left0.91.42.11.21.21.21.21.31.4-0.21.21.5
Liver weight, right0.91.62.41.21.11.11.20.71.5-1.31.31.5
Parametrial fat weight6.612.828.13.53.83.53.80.83.1-5.33.93.1
Retroperitoneal fat weight0.10.41.1-0.6-0.5-0.7-0.5-1.0-0.6-0.6-0.6-0.6
Intraocular pressure1.72.44.5-1.4-1.1-1.2-1.1-2.1-2.1-0.9-1.2-2.1
Extensor digitorum longus weight0.83.217.31.11.30.91.3-1.21.2-4.21.21.2
Soleus weight3.811.114.93.43.53.13.42.23.9-3.03.33.8
Tibialis anterior weight1.86.116.62.32.52.22.50.22.2-4.12.52.2
Tibia length1.13.25.81.81.71.81.82.42.00.51.72.0
Number of licking bursts0.20.20.5-0.4-0.4-0.3-0.4-0.2-0.70.6-0.3-0.7
Food consumed during 24 hour testing period0.50.71.40.60.50.50.51.21.10.60.61.1
Times rat made contact with spout0.30.31.60.20.20.30.20.9-0.11.30.2-0.1
Mean time between licks in bursts1.11.63.11.21.21.01.20.41.5-1.81.21.5
Mean num. licks in bursts0.20.20.40.50.50.50.50.60.50.10.50.5
Std. dev. time between licks in bursts0.30.40.90.60.60.50.60.10.7-1.00.50.7
Water consumed over 24 hours1.41.64.60.90.70.80.72.21.32.00.81.3
Indifference point 0 sec0.40.62.90.40.40.70.31.2-0.41.70.5-0.4
Indifference point AUC1.41.73.5-1.3-1.3-1.3-1.2-1.9-1.2-0.7-1.2-1.2
Indifference point function ln k1.92.77.81.21.11.21.12.81.42.40.91.4
Indifference point function log k1.92.77.81.21.11.21.12.81.42.40.91.4
Delay discounting total patch changes 0 sec0.30.52.00.30.30.60.20.9-0.51.40.5-0.5
Delay discounting total patch changes 12 sec0.60.81.8-0.5-0.6-0.3-0.5-1.3-1.3-0.9-0.2-1.3
Delay discounting total patch changes 18 sec0.20.20.6-0.2-0.2-0.1-0.2-0.7-0.8-0.4-0.0-0.8
Delay discounting total patch changes 24 sec0.60.81.2-0.9-0.9-0.8-0.9-1.1-1.0-0.0-0.8-1.1
Delay discounting total patch changes 6 sec1.11.73.5-1.1-1.0-0.9-1.0-1.8-1.8-0.6-0.9-1.9
Delay discounting time to switch 0 sec0.30.52.90.30.40.30.5-0.70.1-1.70.40.1
Delay discounting water rate 0 sec0.20.41.2-0.5-0.7-0.5-0.70.2-0.31.1-0.7-0.2
Delay discounting water rate 12 sec0.40.60.90.90.80.90.70.40.6-0.90.80.6
Delay discounting water rate 18 sec1.31.82.81.41.31.41.31.71.50.11.31.4
Delay discounting water rate 24 sec0.00.10.3-0.1-0.2-0.1-0.1-0.3-0.0-0.6-0.2-0.0
Delay discounting water rate 6 sec0.10.10.3-0.1-0.3-0.2-0.40.20.40.3-0.50.4
Locomotor activity0.10.21.40.20.30.30.2-0.5-0.1-1.20.3-0.1
Locomotor testing distance0.61.05.9-0.10.1-0.00.0-1.6-0.6-2.40.0-0.5
Locomotor testing rearing0.91.34.8-0.6-0.3-0.5-0.4-2.0-1.1-2.2-0.4-1.1
Light reinforcement 10.30.52.60.00.20.10.1-1.0-0.6-1.60.1-0.5
Light reinforcement 20.20.20.4-0.4-0.3-0.5-0.4-0.6-0.5-0.3-0.5-0.4
Reaction time number correct0.20.30.40.60.60.60.60.40.6-0.50.50.6
Reaction time mean minus median1.11.43.4-1.1-1.0-0.8-1.0-0.7-1.91.1-1.0-1.8
Reaction time mean minus median AUC0.50.61.7-0.7-0.6-0.5-0.6-0.6-1.30.5-0.5-1.3
Reaction time num false alarms0.60.82.2-0.7-0.7-0.5-0.7-0.0-1.21.5-0.7-1.2
Reaction time num false alarms AUC0.50.81.7-0.8-0.7-0.6-0.8-0.2-1.11.3-0.8-1.1
Reaction time trials correct on left0.20.30.40.60.60.60.60.40.6-0.50.50.6
Reaction time trials on left0.20.30.30.60.60.50.60.40.6-0.50.50.6
Reaction time mean0.30.40.9-0.6-0.5-0.4-0.5-0.3-1.00.7-0.5-0.9
Reaction time mean AUC0.70.91.6-0.9-0.9-0.8-0.9-0.5-1.31.0-0.9-1.2
Median of all reaction times0.10.20.4-0.4-0.4-0.4-0.4-0.3-0.60.4-0.4-0.6
Reaction time omissions0.20.20.6-0.3-0.2-0.2-0.2-0.7-0.7-0.6-0.2-0.7
Reaction time false alarm rate0.60.91.7-0.8-0.8-0.7-0.9-0.3-1.21.3-0.8-1.2
Reaction time premature initiation rate0.50.72.20.70.40.80.51.50.71.10.80.6
Reaction time premature initiations0.71.02.51.00.71.00.71.61.00.81.00.9
Std. dev. reaction times1.01.32.5-1.0-1.0-0.8-1.0-0.4-1.61.5-1.0-1.5
Reaction time trials completed0.20.30.30.60.60.50.60.40.6-0.50.50.6
Reaction time trials AUC0.20.30.30.60.50.50.60.40.5-0.40.50.5
Social response proportion4.34.76.62.42.42.52.42.61.80.22.41.9
Social responses1.51.93.31.51.61.61.60.50.7-1.61.80.8
Social time1.62.13.21.61.81.71.70.81.0-1.41.61.0
Conditioned locomotion0.91.11.3-1.1-1.1-1.0-1.1-0.6-1.11.1-1.1-1.1
Cocaine response after cond. corrected0.50.61.40.80.70.90.81.20.60.60.70.6
Cocaine response after cond. not corrected0.50.61.00.80.80.90.91.00.60.30.80.6
Cocaine response before conditioning0.20.21.10.30.40.30.3-0.30.2-1.00.40.2
Saline control response0.10.20.70.30.40.40.4-0.2-0.2-0.80.4-0.2
Condit. Reinf. active minus inactive responses0.30.41.00.60.70.80.61.00.20.60.60.2
Condit. Reinf. active-inactive response ratio0.30.30.80.30.50.60.40.8-0.20.90.4-0.2
Condit. Reinf. active responses0.20.30.60.50.60.60.50.80.30.30.50.3
Condit. Reinf. inactive responses0.10.10.3-0.3-0.4-0.4-0.4-0.5-0.2-0.4-0.3-0.2
Condit. Reinf. lever presses0.71.01.6-1.0-0.9-0.9-1.0-0.8-1.30.7-0.9-1.3
Condit. Reinf. lever reinforcers received0.10.10.30.30.40.40.20.50.00.30.30.0
Pavlov. Cond. lever latency1.72.33.01.51.51.31.60.71.7-1.71.51.7
Pavlov. Cond. magazine entry latency0.30.41.3-0.5-0.5-0.4-0.60.1-0.51.2-0.5-0.5
Pavlov. Cond. change in total contacts0.30.51.4-0.6-0.7-0.6-0.7-0.0-0.61.2-0.7-0.6
Pavlov. Cond. index score1.72.32.8-1.6-1.6-1.5-1.6-1.0-1.71.3-1.5-1.7
Pavlov. Cond. latency score2.32.93.5-1.8-1.8-1.7-1.9-1.2-1.81.3-1.8-1.8
Pavlov. Cond. lever contacts0.81.11.5-1.0-1.1-0.9-1.1-0.7-1.20.9-1.0-1.2
Pavlov. Cond. magazine entry number0.50.71.00.80.80.80.90.30.8-1.00.80.8
Pavlov. Cond. intertrial magazine entries0.50.61.60.80.90.80.90.10.5-1.30.80.5
Pavlov. Cond. lever-magazine prob. diff.1.72.22.7-1.5-1.5-1.4-1.6-0.9-1.61.3-1.5-1.6
Pavlov. Cond. response bias0.81.11.5-1.0-1.0-0.9-1.1-0.5-1.21.2-1.0-1.2
Conditioned reinforcement - actives0.30.31.30.40.60.30.5-0.20.5-1.20.30.6
Conditioned reinforcement - inactives0.40.52.00.00.20.20.2-1.0-0.8-1.40.2-0.7
Conditioned locomotion0.70.81.6-1.0-0.8-1.2-0.9-1.3-0.5-0.5-1.0-0.3
Intermittent access intake day 1-15 change2.12.13.8-1.5-1.2-1.4-1.2-1.9-1.8-0.5-1.5-1.6
Intermittent access intake escalation2.12.13.4-1.5-1.3-1.6-1.3-1.9-1.5-0.3-1.7-1.4
Intermittent access intake escalation 22.42.44.2-1.7-1.4-1.8-1.5-1.6-1.60.3-2.1-1.5
Intermitt. access day 1 inactive lever presses2.02.14.2-1.4-1.4-1.2-1.3-1.5-2.10.4-1.3-2.0
Intermitt. access day 15 inactive lever presses0.10.20.30.30.40.50.40.3-0.50.30.3-0.5
Intermitt. access escalation Index2.21.93.41.51.51.61.51.11.3-0.81.91.2
Intermittent access day 1 total infusions0.40.52.90.40.50.40.5-0.60.2-1.70.60.2
Intermittent access day 15 total infusions1.61.85.5-1.0-0.7-1.1-0.8-2.3-1.0-2.1-0.9-0.9
Intermittent access terminal intake (last 3 days)0.70.84.8-0.10.2-0.10.1-1.4-0.3-2.20.2-0.1
Intermittent access total infusions0.50.63.3-0.3-0.0-0.4-0.1-1.3-0.3-1.8-0.2-0.1
Intermittent access day 1 locomotion0.50.53.1-0.10.1-0.1-0.0-1.1-0.1-1.8-0.0-0.1
Intermittent access day 15 total locomotion0.70.82.2-0.9-0.6-1.0-0.6-1.5-0.4-1.1-0.9-0.4
Intermittent access total locomotion0.30.31.6-0.3-0.0-0.4-0.1-1.0-0.2-1.3-0.3-0.2
Intermittent access standard deviation3.43.78.2-1.9-1.7-2.1-1.7-2.9-1.6-1.5-1.9-1.5
Cocaine induced anxiety0.50.62.4-0.6-0.8-0.5-0.80.3-0.61.5-0.7-0.6
Post-drug Anxiety0.20.30.80.10.00.40.00.4-0.80.90.2-0.8
Baseline Anxiety0.20.20.80.30.40.50.4-0.4-0.4-0.90.5-0.5
Lifetime Intake0.80.94.9-0.30.0-0.3-0.0-1.6-0.5-2.2-0.2-0.3
Incentive Sensitization - Responses0.10.10.30.20.30.20.2-0.10.1-0.50.20.1
Incentive Sensitization - Breakpoint0.00.00.20.10.30.10.2-0.10.0-0.50.20.0
Progressive ratio test 1 active lever presses0.70.71.90.70.80.70.80.00.9-1.40.81.0
Progressive ratio test 1 breakpoint1.21.32.51.11.11.11.10.21.0-1.61.31.2
Progressive ratio test 1 inactive lever presses0.30.31.8-0.20.1-0.20.0-1.0-0.2-1.4-0.5-0.1
Progressive ratio test 2 active lever presses0.30.31.20.30.50.30.4-0.30.4-1.10.40.5
Progressive ratio test 2 breakpoint0.20.20.80.30.60.30.5-0.10.4-0.90.30.5
Progressive ratio test 2 inactive lever presses0.60.73.0-0.10.10.00.1-1.3-0.9-1.7-0.1-0.8
Total sessions with >9 infusions0.60.63.50.30.50.20.5-0.60.6-1.90.30.7
Short access day 1 total inactive lever presses0.20.20.6-0.1-0.10.1-0.1-0.5-0.8-0.40.1-0.7
Short access day 10 total inactive lever presses0.00.00.10.10.20.10.20.20.00.2-0.00.1
Short access day 1 total infusions1.61.74.7-1.1-0.9-1.1-1.0-2.2-1.3-1.6-1.0-1.2
Short access day 10 total infusions0.30.42.20.00.30.10.2-0.9-0.4-1.50.2-0.3
Short access total infusions1.21.34.4-0.7-0.4-0.6-0.4-2.0-1.1-2.1-0.4-0.9
Short access day 1 locomotion0.91.02.3-0.9-0.5-0.9-0.7-1.5-1.2-0.8-1.0-1.1
Short access day 10 total locomotion0.70.71.8-0.8-0.7-0.8-0.7-1.3-0.8-0.9-0.8-0.8
Short access total locomotion0.50.51.4-0.7-0.5-0.7-0.5-1.2-0.5-0.9-0.7-0.4
Compulsive drug intake0.40.41.20.60.30.70.41.10.30.90.80.3
One hour access (0.3 mA shock)0.30.42.1-0.00.2-0.00.2-0.9-0.3-1.40.0-0.2
One hour access (shock baseline)0.50.53.2-0.20.1-0.30.0-1.10.0-1.8-0.30.2
Number of responses in last shaping day1.31.32.6-1.0-0.8-0.9-0.8-1.4-1.5-0.3-1.6-1.4
Context. condit. distance diff. score0.91.11.81.11.21.11.10.40.9-1.41.20.9
Locomotion velocity, session 13.53.84.72.02.01.92.01.42.2-1.62.12.2
Locomotion distance, session 10.20.31.20.40.40.30.5-0.20.6-1.10.50.6
Locomotion velocity, session 20.70.91.51.00.80.90.91.21.10.30.81.1
Locomotion distance, session 20.60.81.01.00.90.91.00.80.9-0.51.00.9
Locomotion velocity, session 30.80.93.0-0.9-1.0-1.0-1.00.2-0.21.7-1.2-0.2
Locomotion distance, session 30.00.00.1-0.1-0.1-0.1-0.10.10.00.4-0.10.0
Stereotopy head waving bouts, day 30.10.20.40.30.30.20.20.40.70.00.20.7
Stereotopy head waving duration, day 31.01.21.9-1.2-1.2-1.4-1.2-1.2-0.70.0-1.3-0.7
Locomotion velocity, session 70.10.10.2-0.1-0.2-0.0-0.1-0.4-0.4-0.2-0.1-0.4
Locomotion distance, session 70.10.10.40.00.10.20.1-0.1-0.60.00.1-0.6
Stereotopy head waving bouts, day 70.50.61.60.70.70.60.70.10.8-1.30.70.8
Stereotopy head waving duration, day 70.80.92.00.90.90.80.90.31.1-1.40.91.1
Locomotion velocity, session 80.60.71.60.60.60.40.60.11.2-1.30.61.2
Locomotion distance, session 82.23.33.91.92.01.81.91.11.9-1.71.91.9
Degree of sensitization distance0.20.20.80.30.40.50.5-0.3-0.4-0.90.5-0.4
Degree of sensitization stereotypy1.41.62.01.31.31.31.40.71.2-1.31.41.2
Condit. Reinf. active minus inactive responses0.40.41.00.50.50.80.61.0-0.20.90.5-0.2
Condit. Reinf. active-inactive response ratio0.20.20.60.40.30.60.40.7-0.20.80.4-0.2
Condit. Reinf. active responses0.30.40.80.60.50.90.60.9-0.20.80.6-0.2
Condit. Reinf. inactive responses0.00.00.1-0.1-0.1-0.0-0.1-0.1-0.30.2-0.1-0.3
Incentive salience index mean0.80.92.21.00.91.21.01.50.21.01.00.2
Condit. Reinf. lever presses2.12.85.41.81.72.01.72.31.20.81.81.2
Time in familiar zone, hab. session 10.40.40.7-0.6-0.5-0.5-0.5-0.8-0.8-0.1-0.6-0.8
Time in novel zone, hab. session 10.30.30.70.50.40.60.50.90.60.30.50.6
Total zone transitions, hab. session 10.81.16.5-0.2-0.0-0.3-0.0-1.8-0.4-2.60.0-0.4
Total locomotion distance, hab. session 10.10.10.60.20.30.20.3-0.3-0.2-0.70.3-0.2
Locomotion velocity, hab. session 10.10.10.6-0.00.10.00.1-0.6-0.3-0.80.1-0.3
Time in familiar zone, hab. session 20.30.30.60.50.50.60.50.80.60.20.50.6
Time in novel zone, hab. session 20.50.61.0-0.7-0.7-0.6-0.7-0.5-1.00.6-0.8-1.0
Total zone transitions, hab. session 20.50.63.50.50.50.50.6-0.60.3-1.90.70.3
Total locomotion distance, hab. session 20.10.10.60.20.30.30.3-0.3-0.1-0.80.4-0.1
Locomotion velocity, hab. session 20.10.10.70.20.20.20.2-0.40.0-0.80.30.0
Novel to familiar place preference ratio0.30.30.5-0.5-0.5-0.5-0.5-0.7-0.7-0.0-0.5-0.7
Novelty place preference0.10.10.2-0.2-0.1-0.1-0.1-0.2-0.4-0.0-0.2-0.4
Time in novel zone, NPP test0.00.00.00.10.10.10.1-0.0-0.2-0.10.0-0.2
Total zone transitions, NPP test0.50.74.50.20.20.20.3-1.2-0.2-2.10.4-0.2
Total locomotion distance, NPP test0.40.51.0-0.6-0.6-0.6-0.6-1.0-0.9-0.3-0.5-0.9
Locomotion velocity, NPP test0.81.21.8-1.1-1.1-1.1-1.0-1.3-1.30.0-1.0-1.3
Pavlov. Cond. lever latency0.50.62.7-0.5-0.3-0.7-0.4-1.30.1-1.6-0.50.1
Pavlov. Cond. magazine entry latency1.31.74.81.11.01.21.02.20.91.81.00.9
Pavlov. Cond. change in total contacts0.60.73.2-0.4-0.5-0.2-0.40.4-1.01.8-0.4-1.0
Pavlov. Cond. index score1.01.33.51.10.91.21.01.90.61.41.00.6
Pavlov. Cond. latency score1.41.74.41.31.11.41.22.10.81.41.20.8
Pavlov. Cond. lever contacts0.50.61.60.60.50.80.61.2-0.11.30.6-0.1
Pavlov. Cond. magazine entry number0.40.52.1-0.5-0.4-0.6-0.4-1.2-0.0-1.4-0.5-0.0
Pavlov. Cond. intertrial magazine entries0.80.93.3-0.5-0.4-0.5-0.3-1.7-0.8-1.8-0.3-0.8
Pavlov. Cond. lever-magazine prob. diff.0.81.02.90.90.81.10.81.70.51.40.90.5
Pavlov. Cond. response bias0.60.72.30.70.50.90.61.40.11.50.70.1
Bone: apparent density1.32.23.21.71.61.81.71.41.3-0.71.81.3
Bone surface0.61.12.41.11.01.11.10.30.9-1.51.10.9
Bone volume0.71.23.21.11.11.11.10.10.9-1.81.20.9
Bone: connectivity density1.52.43.21.71.61.81.71.21.4-1.21.81.4
Bone: cortical apparent density0.70.92.0-0.9-0.8-0.8-0.9-0.2-1.01.4-0.9-1.0
Bone: cortical area0.60.81.1-1.0-1.0-1.0-1.0-0.9-0.90.4-1.0-0.9
Bone: cortical porosity1.11.23.01.10.91.00.91.71.11.00.91.1
Bone: cortical porosity0.70.82.20.80.60.70.61.50.81.10.60.8
Bone: cortical thickness0.81.34.5-1.0-0.9-0.9-1.00.1-1.02.1-1.1-1.0
Bone: cortical thickness0.70.84.70.30.30.40.21.50.22.20.10.2
Bone: cortical tissue density0.50.71.7-0.8-0.7-0.6-0.7-0.1-0.91.3-0.8-0.9
Bone: elastic displacement0.80.91.3-0.9-0.9-0.9-0.9-0.7-1.10.6-0.9-1.1
Bone: elastic work1.01.32.2-1.1-1.1-1.1-1.2-0.4-1.11.5-1.2-1.1
Bone: endosteal estimation0.71.55.5-0.8-0.7-0.9-0.7-2.2-0.6-2.3-0.5-0.6
Bone: endosteal perimeter0.61.35.9-0.6-0.5-0.7-0.5-2.0-0.5-2.4-0.4-0.5
Bone: final force0.10.21.00.00.10.00.1-0.6-0.2-1.00.2-0.2
Bone: final moment0.10.20.9-0.2-0.0-0.2-0.1-0.8-0.4-1.0-0.0-0.4
Bone: marrow area0.71.55.4-0.8-0.7-0.9-0.7-2.2-0.6-2.3-0.5-0.6
Bone: maximum diameter0.50.92.2-1.0-0.9-1.1-1.0-1.5-0.7-0.7-0.9-0.7
Bone: maximum force0.10.21.0-0.2-0.1-0.2-0.1-0.8-0.3-1.0-0.0-0.3
Bone: maximum moment0.20.41.2-0.4-0.3-0.4-0.3-1.1-0.5-1.0-0.3-0.5
Bone: minimum diameter0.30.63.5-0.3-0.3-0.4-0.2-1.30.1-1.9-0.10.1
Bone: periosteal estimation0.51.13.2-0.9-0.9-1.0-0.9-1.8-0.7-1.4-0.7-0.7
Bone: periosteal perimeter0.30.61.5-0.7-0.6-0.7-0.6-1.2-0.5-1.0-0.6-0.5
Bone: post-yield work0.60.81.21.01.01.01.00.50.7-0.91.10.7
Bone: stiffness1.62.64.11.61.71.61.70.61.5-2.01.71.5
Bone: tissue strength0.70.71.1-0.8-0.8-0.7-0.8-0.9-1.10.1-0.7-1.1
Bone: trabecular number1.01.52.31.41.31.51.41.41.0-0.11.51.0
Bone: trabecular spacing0.50.61.0-0.9-0.8-1.0-0.9-1.0-0.6-0.1-1.0-0.6
Bone: trabecular thickness0.20.30.50.60.60.60.50.40.5-0.50.70.5
Bone: trabecular tissue density1.41.93.5-1.4-1.4-1.4-1.5-0.5-1.21.9-1.5-1.2
Breakpoint value in progressive ratio session0.91.02.11.20.91.31.20.80.7-0.61.50.7
Distance traveled before self-admin0.91.01.7-1.2-1.1-1.3-1.1-1.2-0.6-0.1-1.1-0.6
Distance traveled after self-admin1.11.27.1-0.30.1-0.50.0-1.8-0.1-2.7-0.2-0.1
Delta time in closed arm before/after self-admin0.10.10.5-0.1-0.2-0.3-0.2-0.50.4-0.7-0.10.3
Delta time in open arm before/after self-admin0.30.31.10.30.50.40.4-0.5-0.6-1.00.4-0.5
Diff in mean of infusions in LGA sessions0.80.92.01.10.81.31.11.10.60.01.40.6
Extinction: sum of active levers before priming2.62.64.91.72.21.72.11.01.2-1.21.71.3
Active lever presses in extinction session 61.01.01.50.91.10.81.10.41.1-1.11.01.2
Delta distance traveled before/after self-admin1.51.66.01.11.51.11.4-0.30.5-2.51.10.6
Delta ambulatory time before/after self-admin1.11.24.11.01.31.01.3-0.20.3-2.00.90.3
Time in closed arm before self-admin1.11.32.21.31.21.51.41.40.50.21.50.5
Time in closed arm after self-admin0.00.00.10.0-0.1-0.0-0.10.20.30.20.20.2
Time in open arm before self-admin1.92.02.8-1.5-1.6-1.5-1.6-0.9-1.21.2-1.7-1.3
Time in open arm after self-admin1.92.13.4-1.3-1.1-1.2-1.3-1.8-1.9-0.4-1.5-1.8
Sum of active levers in priming session hrs 5-62.72.73.71.81.81.91.81.61.4-0.41.91.5
Time to tail flick, vehicle, before self-admin1.81.82.71.41.41.41.41.31.3-0.31.61.3
Time to tail flick, vehicle, after self-admin0.10.10.1-0.0-0.10.10.0-0.3-0.4-0.40.0-0.4
Time to tail flick, test, before self-admin1.01.03.00.70.60.90.81.70.41.70.60.3
Time to tail flick, test, after self-admin0.50.51.20.60.90.60.91.10.50.80.30.5
Delta time to tail flick, vehicle, before/after SA1.91.82.8-1.3-1.4-1.3-1.3-1.7-1.4-0.4-1.5-1.5
Delta time to tail flick, test, before/after SA0.30.31.0-0.4-0.1-0.6-0.2-1.0-0.0-1.0-0.5-0.0
Ambulatory time before self-admin0.60.61.2-0.9-1.0-1.1-1.0-0.8-0.40.2-0.9-0.4
Ambulatory time after self-admin0.80.94.30.60.80.50.8-0.50.7-2.10.60.7
Total heroin consumption3.54.27.02.32.02.52.22.11.7-0.62.61.7
Area under the delay curve0.20.20.4-0.5-0.5-0.6-0.5-0.4-0.10.1-0.5-0.1
Delay disc. indifference point, 0s delay0.40.42.40.20.30.10.3-0.60.4-1.50.40.4
Delay disc. indifference point, 16s delay0.40.40.8-0.6-0.7-0.9-0.7-0.70.3-0.4-0.60.2
Delay disc. indifference point, 2s delay0.20.20.2-0.5-0.5-0.4-0.5-0.2-0.50.5-0.5-0.5
Delay disc. indifference point, 24s delay0.20.21.1-0.2-0.2-0.2-0.20.4-0.01.0-0.2-0.0
Delay disc. indifference point, 4s delay0.10.20.5-0.1-0.0-0.0-0.0-0.6-0.5-0.7-0.0-0.5
Delay disc. indifference point, 8s delay0.00.00.0-0.2-0.1-0.2-0.1-0.10.0-0.0-0.10.0
Delay discount exponential model param0.10.10.20.30.40.40.40.1-0.0-0.30.3-0.0
Delay discount hyperbolic model param0.10.10.20.40.40.40.40.20.1-0.20.40.2
Fecal boli incidents, locomotor time 10.10.20.40.00.0-0.10.00.60.60.6-0.10.6
Change in fecal boli incidents, locomotor task0.10.10.6-0.1-0.10.0-0.10.3-0.50.8-0.1-0.4
Time >=10cm from walls, locomotor time 10.10.10.40.10.40.20.20.50.20.70.10.2
Bouts of movement, locomotor time 10.40.51.10.50.40.50.51.10.80.70.40.8
Total resting periods, locomotor time 10.50.62.00.40.30.40.31.30.61.40.30.6
Rest time, locomotor task time 10.30.30.9-0.6-0.5-0.5-0.5-0.0-0.51.0-0.7-0.5
Distance moved, locomotor task time 10.20.21.40.10.10.20.2-0.6-0.2-1.20.3-0.2
Vertical activity count, locomotor time 10.30.31.50.30.40.40.4-0.5-0.1-1.20.5-0.1
Time >=10cm from walls, locomotor time 20.20.21.1-0.00.1-0.0-0.10.50.21.0-0.20.2
Bouts of movement, locomotor time 20.20.21.40.10.20.20.20.80.01.2-0.00.0
Total resting periods, locomotor time 20.20.30.80.30.40.30.30.80.30.90.10.4
Rest time, locomotor task time 20.20.21.3-0.2-0.2-0.3-0.30.50.11.1-0.30.0
Distance moved, locomotor task time 20.50.62.0-0.5-0.5-0.5-0.4-1.4-0.7-1.4-0.4-0.6
Vertical activity count, locomotor time 20.10.10.9-0.00.0-0.00.1-0.6-0.1-0.90.2-0.1
Weight adjusted by age0.60.63.70.40.40.60.4-0.8-0.4-1.90.5-0.3
Seeking ratio, delayed vs. immediate footshock0.50.50.9-0.7-0.7-0.7-0.8-0.2-0.71.0-0.8-0.7
Locomotion in novel chamber4.05.07.0-2.3-2.2-2.3-2.2-2.6-2.3-0.2-2.4-2.5
Locomotion in novel chamber post-restriction0.40.40.7-0.6-0.8-0.5-0.8-0.3-0.80.7-0.4-0.8
Progressive ratio0.50.51.1-0.6-0.6-0.5-0.5-1.1-1.0-0.6-0.5-0.9
Food seeking constrained by brief footshock0.10.10.3-0.3-0.3-0.3-0.30.1-0.10.5-0.40.1
Seeking ratio, punishment vs. effort0.40.41.10.40.30.30.31.10.91.00.10.8
Run reversals in cocaine runway, females0.10.10.2-0.2-0.0-0.2-0.0-0.1-0.40.3-0.4-0.4
Run reversals in cocaine runway, males1.91.84.0-1.2-1.1-1.2-1.1-2.0-1.5-1.0-1.2-1.5
Latency to leave start box in cocaine runway0.10.10.20.20.20.20.20.50.40.40.20.4
Latency to leave start box in cocaine runway, F0.70.81.20.80.80.70.81.11.10.30.91.1
Latency to leave start box in cocaine runway, M0.10.10.20.10.1-0.00.1-0.20.3-0.5-0.00.3
Cd content in liver0.40.41.80.50.60.50.6-0.10.5-1.30.60.5
Co content in liver0.20.20.50.40.40.30.40.20.7-0.60.40.7
Cu content in liver0.40.53.30.20.00.30.01.2-0.01.80.1-0.1
Fe content in liver0.91.01.41.11.21.21.21.10.9-0.21.10.9
K content in liver1.21.22.31.11.00.91.01.21.4-0.20.91.5
Mg content in liver0.10.10.1-0.3-0.3-0.3-0.3-0.2-0.20.1-0.3-0.1
Mn content in liver0.50.61.80.50.40.50.41.30.71.20.40.8
Na content in liver0.30.30.5-0.6-0.6-0.7-0.6-0.6-0.30.1-0.7-0.3
Rb content in liver0.10.20.9-0.1-0.1-0.1-0.1-0.7-0.2-1.0-0.0-0.2
Se content in liver0.60.71.8-0.8-0.8-0.7-0.8-0.1-0.81.3-0.8-0.7
Sr content in liver0.60.62.20.60.70.60.7-0.20.6-1.50.70.6
Zn content in liver0.20.20.7-0.4-0.4-0.2-0.4-0.2-0.80.5-0.3-0.8