Hub : Genes

Hap1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000014819 0.24 0.09 2.6e-07 0.11 0.11 0.09 0.09 1.4e-06 2.8e-06 1.4e-05 1.3e-05
2 Brain gene expression ENSRNOG00000014819 0.27 0.07 0.0e+00 0.39 0.37 0.38 0.39 8.2e-39 1.9e-35 1.7e-36 6.5e-38
3 Brain isoform ratio ENSRNOT00000020603 0.04 0.02 8.3e-05 0.03 0.05 0.04 0.05 5.4e-04 4.3e-05 2.1e-04 4.3e-05
4 Brain isoform ratio ENSRNOT00000090702 0.04 0.02 6.3e-05 0.03 0.05 0.04 0.05 7.9e-04 3.8e-05 8.4e-05 3.9e-05
5 IL gene expression ENSRNOG00000014819 0.23 0.11 2.5e-04 0.11 0.14 0.09 0.11 1.6e-03 3.3e-04 3.2e-03 1.6e-03
6 LHb isoform ratio ENSRNOT00000020603 0.13 0.08 5.8e-03 0.11 0.08 0.11 0.11 1.5e-03 7.0e-03 1.6e-03 1.5e-03
7 NAcc gene expression ENSRNOG00000014819 0.39 0.08 0.0e+00 0.36 0.38 0.38 0.38 1.8e-27 5.0e-30 1.6e-29 5.4e-30
8 OFC gene expression ENSRNOG00000014819 0.38 0.11 1.3e-09 0.38 0.33 0.34 0.38 6.9e-10 1.5e-08 7.0e-09 4.5e-10
9 PL gene expression ENSRNOG00000014819 0.17 0.06 9.2e-13 0.18 0.17 0.15 0.19 4.8e-14 8.4e-13 2.5e-11 2.9e-14
10 PL isoform ratio ENSRNOT00000020603 0.03 0.02 9.5e-03 0 0.02 0 0 3.2e-01 1.6e-02 3.2e-01 3.5e-01
11 PL isoform ratio ENSRNOT00000090702 0.03 0.02 5.4e-03 0 0.02 0 0 2.7e-01 9.2e-03 2.4e-01 2.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail0.51.62.61.31.41.6-1.40.31.41.00.71.41.3-1.3
BMI without tail2.45.17.72.62.42.0-1.91.82.52.52.02.82.0-2.0
Body weight0.10.62.4-0.10.31.5-1.5-0.20.30.10.30.30.8-0.8
Epididymis fat weight0.10.31.10.20.41.0-0.80.20.40.40.60.50.5-0.5
Glucose0.30.51.11.00.90.7-0.30.30.90.70.30.90.6-0.6
Heart weight0.81.12.90.90.91.4-1.70.50.90.90.70.71.1-1.1
Left kidney weight0.31.02.1-0.9-0.7-0.50.7-1.1-0.7-0.6-1.3-0.6-1.51.4
Right kidney weight0.41.32.4-0.9-0.7-0.91.0-1.4-0.8-0.7-1.5-0.8-1.61.6
Tail length0.82.53.81.41.41.5-1.61.91.41.81.91.71.4-1.4
Length with tail0.10.31.1-0.7-0.31.0-1.10.3-0.4-0.20.4-0.40.2-0.2
Length without tail1.53.26.9-2.6-2.1-0.40.5-1.6-2.2-2.2-1.5-2.4-1.21.2
Liver weight, left0.00.10.10.30.00.0-0.10.30.10.20.30.30.2-0.2
Liver weight, right0.71.22.6-0.6-0.6-1.41.6-0.9-0.8-0.5-0.9-0.4-1.61.6
Parametrial fat weight0.00.10.2-0.2-0.3-0.20.3-0.1-0.3-0.0-0.2-0.5-0.40.4
Retroperitoneal fat weight0.00.10.2-0.10.10.4-0.3-0.2-0.10.20.10.1-0.40.4
Intraocular pressure4.66.57.62.52.62.0-2.52.62.62.52.62.52.8-2.8
Extensor digitorum longus weight5.421.628.34.14.44.9-5.34.44.44.04.94.45.1-5.1
Soleus weight0.10.40.80.50.70.9-0.70.30.70.50.70.60.7-0.7
Tibialis anterior weight1.13.74.81.71.92.1-2.11.81.81.52.01.72.2-2.2
Tibia length0.20.50.9-0.8-0.80.8-0.7-0.9-0.8-0.8-0.6-0.9-0.10.1
Number of licking bursts0.70.81.4-0.6-0.8-1.00.9-1.2-0.8-0.9-1.2-0.9-0.80.8
Food consumed during 24 hour testing period0.00.00.2-0.00.00.3-0.2-0.4-0.1-0.2-0.3-0.00.1-0.1
Times rat made contact with spout0.00.10.20.20.10.3-0.4-0.10.10.1-0.00.10.4-0.4
Mean time between licks in bursts0.20.20.50.60.20.6-0.7-0.40.30.1-0.20.30.7-0.6
Mean num. licks in bursts1.41.72.10.91.21.5-1.41.41.11.21.41.31.3-1.3
Std. dev. time between licks in bursts0.20.20.40.60.50.3-0.10.40.60.40.30.40.4-0.4
Water consumed over 24 hours1.11.32.1-1.0-1.0-1.00.9-1.5-1.0-1.1-1.4-1.2-1.01.0
Indifference point 0 sec0.20.30.7-0.5-0.7-0.90.50.0-0.4-0.0-0.1-0.7-0.60.6
Indifference point AUC0.30.40.9-0.6-0.4-0.90.9-0.5-0.4-0.5-0.5-0.3-0.60.6
Indifference point function ln k0.30.40.9-0.7-0.90.10.1-0.5-0.9-0.6-0.5-1.0-0.60.6
Indifference point function log k0.30.40.9-0.7-0.90.10.1-0.5-0.9-0.6-0.5-1.0-0.60.6
Delay discounting total patch changes 0 sec0.10.20.5-0.5-0.6-0.70.40.0-0.3-0.0-0.0-0.7-0.50.5
Delay discounting total patch changes 12 sec1.62.26.0-1.3-1.2-2.52.1-0.9-1.1-0.9-1.1-1.0-1.61.6
Delay discounting total patch changes 18 sec0.10.11.1-0.2-0.1-1.00.60.10.10.10.00.0-0.20.2
Delay discounting total patch changes 24 sec0.20.30.8-0.4-0.6-0.90.80.0-0.3-0.2-0.2-0.4-0.60.6
Delay discounting total patch changes 6 sec0.10.10.70.10.0-0.80.30.50.20.50.40.3-0.10.1
Delay discounting time to switch 0 sec0.71.12.01.11.40.2-0.61.21.31.30.81.20.8-0.9
Delay discounting water rate 0 sec0.00.00.20.1-0.30.5-0.2-0.1-0.2-0.00.1-0.2-0.00.0
Delay discounting water rate 12 sec0.20.30.4-0.4-0.6-0.60.6-0.5-0.6-0.5-0.6-0.5-0.60.6
Delay discounting water rate 18 sec2.53.34.6-1.9-2.2-0.71.2-1.8-2.1-2.0-1.9-2.1-1.81.8
Delay discounting water rate 24 sec0.10.20.40.50.60.4-0.30.30.40.50.30.60.3-0.3
Delay discounting water rate 6 sec1.21.72.4-1.1-1.3-1.11.5-1.2-1.4-1.2-1.2-1.1-1.61.5
Locomotor activity0.50.82.3-0.4-0.4-1.51.3-0.8-0.4-0.3-1.0-0.4-1.01.0
Locomotor testing distance0.40.72.4-0.3-0.6-1.61.4-0.6-0.3-0.3-0.9-0.3-0.90.9
Locomotor testing rearing0.30.51.90.70.4-1.41.10.60.60.60.00.5-0.40.4
Light reinforcement 10.50.91.5-1.1-0.9-1.11.2-0.6-0.8-0.5-0.6-0.9-1.21.2
Light reinforcement 20.00.10.2-0.1-0.1-0.40.40.3-0.10.00.1-0.1-0.30.3
Reaction time number correct0.10.10.40.30.00.6-0.6-0.10.1-0.1-0.1-0.30.5-0.5
Reaction time mean minus median0.10.10.40.0-0.1-0.0-0.30.20.0-0.20.50.10.6-0.6
Reaction time mean minus median AUC0.10.10.5-0.2-0.4-0.70.30.0-0.3-0.50.1-0.20.2-0.2
Reaction time num false alarms0.30.40.8-0.4-0.4-0.80.9-0.9-0.4-0.5-0.9-0.5-0.60.6
Reaction time num false alarms AUC0.40.61.2-0.6-0.7-0.80.9-1.1-0.6-0.7-0.9-0.8-0.70.7
Reaction time trials correct on left0.10.10.40.30.00.6-0.6-0.10.1-0.1-0.1-0.30.5-0.5
Reaction time trials on left0.10.10.30.2-0.00.5-0.6-0.10.0-0.1-0.1-0.40.5-0.4
Reaction time mean2.02.77.1-1.3-1.6-2.72.1-1.1-1.6-1.5-1.3-1.2-1.51.5
Reaction time mean AUC1.21.65.6-0.8-1.2-2.41.8-0.6-1.1-1.1-0.9-0.8-1.21.1
Median of all reaction times3.34.510.9-1.6-2.0-3.32.7-1.5-2.0-1.8-1.8-1.6-2.12.1
Reaction time omissions1.92.54.2-1.6-1.4-2.02.0-1.2-1.5-1.4-1.5-1.5-1.61.6
Reaction time false alarm rate0.30.51.0-0.6-0.6-0.91.0-0.8-0.5-0.5-0.7-0.5-0.70.7
Reaction time premature initiation rate0.10.10.40.20.60.10.40.40.20.50.20.3-0.40.4
Reaction time premature initiations0.10.10.50.50.70.4-0.10.40.30.50.30.3-0.0-0.0
Std. dev. reaction times0.30.51.5-0.6-0.7-1.20.8-0.4-0.7-0.8-0.4-0.5-0.30.3
Reaction time trials completed0.10.10.30.2-0.00.5-0.6-0.10.0-0.1-0.1-0.40.5-0.4
Reaction time trials AUC0.10.10.20.2-0.10.5-0.5-0.20.0-0.2-0.2-0.40.4-0.4
Social response proportion2.22.43.81.71.81.5-1.31.31.91.91.31.71.1-1.1
Social responses0.20.20.60.70.60.2-0.10.30.70.80.10.40.1-0.1
Social time0.10.20.60.0-0.30.3-0.80.40.00.10.5-0.00.7-0.7
Conditioned locomotion0.10.10.2-0.10.0-0.30.4-0.20.10.2-0.3-0.3-0.40.4
Cocaine response after cond. corrected0.10.20.5-0.3-0.3-0.20.5-0.3-0.2-0.0-0.4-0.3-0.70.7
Cocaine response after cond. not corrected0.40.50.9-0.7-0.8-0.50.5-0.6-0.7-0.4-0.6-0.7-1.01.0
Cocaine response before conditioning0.40.51.0-0.9-0.9-0.50.1-0.5-1.0-0.8-0.4-0.9-0.40.4
Saline control response0.10.10.2-0.2-0.30.3-0.40.4-0.2-0.00.2-0.40.3-0.3
Condit. Reinf. active minus inactive responses0.60.82.0-0.6-0.9-1.41.2-0.5-0.9-0.7-0.6-0.7-0.90.9
Condit. Reinf. active-inactive response ratio0.00.00.2-0.1-0.3-0.50.20.1-0.3-0.10.0-0.2-0.10.1
Condit. Reinf. active responses1.01.43.7-0.8-1.0-1.91.7-0.7-1.1-1.0-0.9-1.0-1.21.2
Condit. Reinf. inactive responses1.11.42.3-1.1-1.0-1.51.5-0.9-1.1-1.2-1.0-1.1-1.21.2
Condit. Reinf. lever presses0.30.40.80.80.7-0.20.20.90.70.70.80.70.3-0.3
Condit. Reinf. lever reinforcers received0.81.13.2-0.6-0.8-1.81.6-0.5-0.8-0.7-0.7-0.7-1.11.1
Pavlov. Cond. lever latency0.10.10.6-0.30.00.8-0.70.1-0.10.10.10.00.3-0.3
Pavlov. Cond. magazine entry latency0.00.00.20.40.20.1-0.10.00.30.20.20.30.1-0.1
Pavlov. Cond. change in total contacts0.40.61.4-0.4-0.6-1.21.1-0.6-0.6-0.7-0.6-0.8-0.80.8
Pavlov. Cond. index score0.10.10.40.40.1-0.60.6-0.10.30.00.00.1-0.20.2
Pavlov. Cond. latency score0.10.10.20.40.2-0.40.4-0.00.30.10.10.2-0.10.1
Pavlov. Cond. lever contacts0.10.10.30.50.1-0.50.60.00.30.10.00.1-0.30.2
Pavlov. Cond. magazine entry number0.30.40.70.20.60.8-0.80.60.40.40.50.40.8-0.8
Pavlov. Cond. intertrial magazine entries0.20.30.9-1.0-0.60.3-0.4-0.3-0.8-0.5-0.2-0.6-0.10.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.30.0-0.70.6-0.20.1-0.0-0.00.1-0.30.3
Pavlov. Cond. response bias0.20.30.90.0-0.4-1.00.9-0.4-0.2-0.3-0.4-0.3-0.80.7
Conditioned reinforcement - actives0.60.61.01.00.7-0.2-0.31.00.80.90.90.80.6-0.7
Conditioned reinforcement - inactives1.82.13.1-1.8-1.7-1.01.0-1.5-1.7-1.8-1.5-1.6-1.01.0
Conditioned locomotion3.03.65.12.12.10.4-1.12.22.32.22.02.21.7-1.7
Intermittent access intake day 1-15 change2.62.63.9-1.8-1.8-0.71.5-1.8-1.7-2.0-1.6-1.6-1.41.4
Intermittent access intake escalation3.23.14.5-2.1-1.8-0.91.8-2.0-1.7-2.0-1.9-1.6-1.61.6
Intermittent access intake escalation 21.61.62.4-1.4-1.3-0.41.2-1.5-1.3-1.5-1.4-1.3-1.11.1
Intermitt. access day 1 inactive lever presses1.01.11.8-1.4-1.1-0.20.9-0.9-1.2-1.0-1.2-1.1-1.11.1
Intermitt. access day 15 inactive lever presses3.94.36.5-2.5-2.2-1.82.1-1.5-2.3-2.3-1.8-2.3-1.91.9
Intermitt. access escalation Index0.00.00.10.10.30.3-0.20.00.0-0.0-0.30.0-0.00.0
Intermittent access day 1 total infusions0.10.10.3-0.0-0.0-0.2-0.30.60.10.10.20.10.3-0.3
Intermittent access day 15 total infusions1.21.31.9-1.4-1.3-0.81.1-0.9-1.1-1.3-1.3-1.1-1.11.0
Intermittent access terminal intake (last 3 days)1.41.52.3-1.4-1.5-0.91.1-0.9-1.4-1.4-1.3-1.4-1.01.0
Intermittent access total infusions0.30.40.8-0.6-0.9-0.60.4-0.2-0.7-0.7-0.7-0.7-0.50.5
Intermittent access day 1 locomotion0.10.10.2-0.3-0.0-0.5-0.10.40.0-0.00.20.10.3-0.3
Intermittent access day 15 total locomotion0.70.71.3-1.1-0.9-0.90.8-0.9-0.8-1.1-0.9-0.7-0.40.4
Intermittent access total locomotion0.20.30.7-0.7-0.4-0.80.7-0.4-0.3-0.5-0.5-0.2-0.30.3
Intermittent access standard deviation0.80.81.4-1.2-0.9-0.41.0-0.8-1.0-1.0-1.0-0.8-0.90.9
Cocaine induced anxiety0.50.62.50.30.21.6-1.10.70.40.70.60.40.6-0.6
Post-drug Anxiety0.70.72.80.20.61.7-1.20.80.50.70.90.50.7-0.7
Baseline Anxiety0.20.20.50.30.7-0.0-0.10.50.40.30.70.40.4-0.4
Lifetime Intake0.50.61.3-0.7-1.1-0.90.6-0.1-1.0-0.8-0.7-1.0-0.60.6
Incentive Sensitization - Responses0.40.41.2-1.1-0.7-0.50.3-0.3-0.8-0.9-0.2-0.8-0.10.2
Incentive Sensitization - Breakpoint0.50.51.3-1.1-0.7-0.50.4-0.3-0.9-1.0-0.2-0.9-0.20.2
Progressive ratio test 1 active lever presses0.30.30.7-0.5-0.8-0.60.4-0.2-0.8-0.6-0.4-0.7-0.40.4
Progressive ratio test 1 breakpoint0.30.30.6-0.5-0.8-0.70.5-0.2-0.7-0.6-0.4-0.6-0.40.4
Progressive ratio test 1 inactive lever presses1.51.62.4-1.3-1.5-1.21.2-0.9-1.5-1.3-1.1-1.5-1.21.2
Progressive ratio test 2 active lever presses0.91.01.7-1.3-1.1-0.80.7-0.6-1.2-1.2-0.8-1.2-0.70.7
Progressive ratio test 2 breakpoint0.70.71.5-1.2-1.0-0.60.6-0.5-1.1-1.1-0.6-1.1-0.50.5
Progressive ratio test 2 inactive lever presses1.41.73.0-1.7-1.6-0.70.9-0.9-1.6-1.6-1.2-1.6-0.90.9
Total sessions with >9 infusions0.30.31.00.50.6-0.0-0.21.00.60.70.50.70.4-0.4
Short access day 1 total inactive lever presses1.31.42.3-1.4-1.5-1.00.8-0.8-1.5-1.3-1.1-1.5-0.90.9
Short access day 10 total inactive lever presses0.20.20.50.10.30.4-0.50.70.20.40.50.20.4-0.4
Short access day 1 total infusions1.41.42.4-1.2-1.4-1.51.1-0.4-1.4-1.1-1.0-1.4-1.11.1
Short access day 10 total infusions0.10.10.4-0.0-0.3-0.2-0.20.6-0.2-0.10.2-0.20.3-0.3
Short access total infusions0.70.81.6-0.9-1.2-1.10.7-0.0-1.2-0.9-0.6-1.1-0.80.7
Short access day 1 locomotion0.30.31.80.0-0.2-1.30.90.5-0.2-0.0-0.0-0.1-0.40.4
Short access day 10 total locomotion0.10.20.8-0.70.0-0.90.5-0.1-0.0-0.3-0.20.10.0-0.0
Short access total locomotion0.10.10.5-0.3-0.1-0.70.30.3-0.1-0.2-0.0-0.00.1-0.1
Compulsive drug intake0.40.40.70.30.60.5-0.80.60.50.60.80.40.7-0.7
One hour access (0.3 mA shock)0.10.10.4-0.2-0.4-0.60.20.2-0.3-0.30.1-0.3-0.0-0.0
One hour access (shock baseline)0.00.00.10.1-0.3-0.30.20.2-0.2-0.1-0.2-0.1-0.10.1
Number of responses in last shaping day0.00.00.1-0.20.00.20.20.00.0-0.0-0.20.1-0.10.1
Context. condit. distance diff. score2.53.14.02.01.71.7-1.81.91.81.91.71.71.5-1.5
Locomotion velocity, session 10.00.00.1-0.1-0.1-0.20.1-0.0-0.10.0-0.1-0.3-0.20.2
Locomotion distance, session 10.60.81.20.60.61.1-1.10.90.80.71.00.71.0-0.9
Locomotion velocity, session 20.00.00.1-0.10.0-0.30.3-0.00.00.1-0.1-0.1-0.40.4
Locomotion distance, session 20.00.00.2-0.3-0.30.4-0.3-0.1-0.1-0.00.1-0.2-0.00.0
Locomotion velocity, session 30.70.81.41.00.81.0-0.81.01.01.20.91.00.6-0.6
Locomotion distance, session 30.80.91.50.90.70.8-1.01.20.91.01.10.70.9-0.9
Stereotopy head waving bouts, day 31.41.62.5-1.3-1.2-0.91.2-1.3-1.2-1.1-1.4-1.1-1.61.6
Stereotopy head waving duration, day 30.30.40.8-0.9-0.6-0.10.4-0.7-0.7-0.6-0.7-0.5-0.80.7
Locomotion velocity, session 70.10.10.3-0.1-0.00.3-0.6-0.3-0.1-0.1-0.1-0.20.2-0.2
Locomotion distance, session 71.01.32.60.90.91.1-1.61.20.90.91.30.71.3-1.3
Stereotopy head waving bouts, day 71.21.42.1-1.0-1.1-1.11.5-1.2-1.0-1.1-1.2-0.9-1.41.4
Stereotopy head waving duration, day 71.92.33.1-1.5-1.2-1.31.8-1.6-1.3-1.4-1.6-1.2-1.71.7
Locomotion velocity, session 81.21.44.21.00.62.1-2.00.70.80.81.00.71.2-1.2
Locomotion distance, session 80.81.11.61.20.91.2-1.21.11.11.11.00.90.9-0.9
Degree of sensitization distance0.10.10.70.20.20.4-0.80.10.10.10.30.10.4-0.4
Degree of sensitization stereotypy0.91.02.0-0.8-0.8-1.11.4-0.9-0.8-0.9-1.0-0.7-1.21.2
Condit. Reinf. active minus inactive responses0.10.10.20.10.1-0.40.40.20.10.2-0.00.2-0.30.3
Condit. Reinf. active-inactive response ratio0.20.20.40.40.5-0.60.50.40.40.50.00.5-0.40.3
Condit. Reinf. active responses0.10.10.2-0.2-0.2-0.30.40.1-0.2-0.1-0.1-0.0-0.40.4
Condit. Reinf. inactive responses0.30.30.7-0.8-0.80.10.1-0.2-0.8-0.7-0.2-0.7-0.30.3
Incentive salience index mean0.10.10.2-0.2-0.1-0.50.40.0-0.2-0.0-0.1-0.0-0.40.4
Condit. Reinf. lever presses0.10.10.3-0.5-0.30.4-0.30.1-0.3-0.10.1-0.10.0-0.0
Time in familiar zone, hab. session 11.21.11.5-1.2-1.0-0.60.9-1.2-1.1-1.2-1.2-1.1-1.01.0
Time in novel zone, hab. session 10.20.20.70.90.5-0.3-0.10.30.50.60.30.60.2-0.2
Total zone transitions, hab. session 12.23.14.51.61.62.1-2.11.61.71.61.61.71.8-1.8
Total locomotion distance, hab. session 10.10.20.30.50.30.5-0.60.60.50.50.40.40.4-0.4
Locomotion velocity, hab. session 10.40.61.00.80.61.0-0.90.90.80.70.70.60.7-0.7
Time in familiar zone, hab. session 20.70.71.1-1.0-0.7-0.11.1-1.0-0.6-0.7-0.8-0.7-1.01.0
Time in novel zone, hab. session 20.10.10.80.40.1-0.9-0.1-0.0-0.00.1-0.20.1-0.00.0
Total zone transitions, hab. session 20.91.21.80.91.11.1-1.30.91.11.01.01.11.2-1.2
Total locomotion distance, hab. session 20.10.20.40.50.40.3-0.60.20.40.30.20.40.6-0.6
Locomotion velocity, hab. session 20.40.60.90.80.80.6-1.00.60.80.70.60.70.9-0.9
Novel to familiar place preference ratio0.40.41.00.80.40.1-0.41.00.60.70.70.60.5-0.5
Novelty place preference0.20.20.60.60.2-0.1-0.20.70.30.50.40.30.2-0.3
Time in novel zone, NPP test0.10.10.30.2-0.2-0.60.20.3-0.10.1-0.0-0.2-0.20.2
Total zone transitions, NPP test1.72.43.51.21.51.6-1.91.51.51.41.61.31.7-1.7
Total locomotion distance, NPP test0.20.30.60.40.40.4-0.80.50.50.40.40.30.7-0.7
Locomotion velocity, NPP test1.21.72.51.11.11.3-1.61.31.21.11.31.11.5-1.5
Pavlov. Cond. lever latency1.62.03.31.71.81.1-0.91.21.71.51.21.61.3-1.3
Pavlov. Cond. magazine entry latency3.64.75.6-2.0-2.4-1.82.2-2.0-2.3-2.1-2.0-2.3-2.32.3
Pavlov. Cond. change in total contacts2.72.94.0-1.8-2.0-1.51.6-1.3-1.8-1.5-1.6-1.8-1.81.8
Pavlov. Cond. index score2.63.35.0-2.0-2.2-1.31.5-1.6-2.1-1.9-1.6-2.1-1.71.7
Pavlov. Cond. latency score2.73.55.4-2.1-2.3-1.31.4-1.7-2.2-2.0-1.7-2.1-1.71.7
Pavlov. Cond. lever contacts0.91.12.2-1.4-1.5-0.50.5-0.9-1.3-1.2-0.8-1.3-0.70.7
Pavlov. Cond. magazine entry number4.45.56.72.42.61.9-2.42.02.52.42.12.52.4-2.4
Pavlov. Cond. intertrial magazine entries1.21.51.81.31.21.2-1.31.01.11.11.11.21.3-1.3
Pavlov. Cond. lever-magazine prob. diff.2.53.24.3-1.9-2.1-1.41.6-1.6-2.0-1.8-1.6-2.0-1.81.8
Pavlov. Cond. response bias2.02.53.5-1.6-1.9-1.31.6-1.1-1.8-1.5-1.3-1.8-1.71.7
Bone: apparent density0.60.91.5-1.2-1.0-0.91.2-0.6-0.9-0.9-0.8-0.9-1.01.0
Bone surface0.30.51.1-1.0-0.8-0.60.5-0.2-0.7-0.8-0.4-0.9-0.40.4
Bone volume0.40.71.6-1.3-1.0-0.80.8-0.5-0.9-1.0-0.6-1.1-0.60.6
Bone: connectivity density0.71.02.0-1.0-0.9-1.31.4-0.6-0.9-0.9-0.9-0.8-1.11.1
Bone: cortical apparent density4.45.88.4-2.6-2.9-1.62.2-2.2-2.6-2.6-2.3-2.7-2.32.3
Bone: cortical area1.21.83.2-1.8-1.6-1.21.0-0.9-1.4-1.3-1.0-1.6-1.21.2
Bone: cortical porosity1.21.32.11.51.40.3-0.31.31.31.01.11.31.0-1.1
Bone: cortical porosity1.11.11.81.31.30.4-0.51.21.31.11.11.21.0-1.0
Bone: cortical thickness2.23.65.0-2.2-2.2-1.51.6-1.5-2.0-1.6-1.7-2.1-2.22.2
Bone: cortical thickness2.02.44.6-1.3-1.3-2.02.0-0.8-1.2-0.8-1.2-1.3-2.22.1
Bone: cortical tissue density4.35.68.1-2.6-2.8-1.62.2-2.2-2.5-2.6-2.2-2.6-2.22.2
Bone: elastic displacement2.83.24.12.02.01.2-1.41.91.81.81.91.91.7-1.7
Bone: elastic work1.01.42.11.21.40.8-0.71.41.31.31.31.40.9-0.9
Bone: endosteal estimation1.32.84.41.51.71.0-1.71.91.71.31.91.42.1-2.1
Bone: endosteal perimeter0.40.71.60.60.90.2-0.80.90.80.40.90.71.3-1.2
Bone: final force2.44.05.7-2.3-2.3-1.71.6-1.7-2.1-2.0-1.8-2.4-2.02.0
Bone: final moment2.13.45.1-2.3-2.1-1.51.4-1.5-1.9-1.8-1.6-2.3-1.81.8
Bone: marrow area1.22.64.11.41.61.0-1.61.81.61.21.81.32.0-2.0
Bone: maximum diameter0.61.22.2-1.5-1.1-1.31.0-0.6-1.1-1.2-0.8-1.3-0.90.9
Bone: maximum force0.30.51.2-1.1-0.8-0.50.3-0.3-0.7-0.7-0.4-1.0-0.50.5
Bone: maximum moment0.10.30.9-1.0-0.6-0.30.1-0.1-0.5-0.5-0.1-0.8-0.30.3
Bone: minimum diameter0.10.20.40.20.20.1-0.40.60.50.30.60.40.6-0.6
Bone: periosteal estimation0.00.10.2-0.3-0.0-0.4-0.10.50.1-0.10.4-0.30.3-0.3
Bone: periosteal perimeter0.00.00.1-0.20.2-0.4-0.10.20.2-0.10.20.00.3-0.3
Bone: post-yield work0.20.20.60.50.20.2-0.80.40.30.30.50.30.6-0.6
Bone: stiffness1.11.73.1-1.8-1.6-0.80.9-1.0-1.4-1.4-1.1-1.7-1.21.2
Bone: tissue strength0.30.31.4-0.3-0.31.2-0.9-0.1-0.2-0.20.1-0.30.5-0.5
Bone: trabecular number1.42.23.9-1.5-1.4-1.52.0-1.2-1.4-1.4-1.4-1.3-1.61.5
Bone: trabecular spacing0.91.22.30.80.91.5-1.50.90.90.81.10.81.3-1.3
Bone: trabecular thickness0.40.51.1-0.8-0.4-1.10.9-0.7-0.4-0.6-0.7-0.5-0.70.7
Bone: trabecular tissue density0.50.71.6-1.0-1.00.20.0-0.6-1.2-0.7-0.6-1.3-0.70.7
Breakpoint value in progressive ratio session0.20.20.60.30.8-0.20.30.40.60.50.40.50.2-0.2
Distance traveled before self-admin2.02.23.61.91.10.8-1.21.81.41.41.81.41.4-1.5
Distance traveled after self-admin1.11.22.21.51.20.9-0.90.61.31.10.71.31.0-1.0
Delta time in closed arm before/after self-admin0.20.20.30.1-0.60.6-0.2-0.6-0.4-0.4-0.6-0.3-0.00.0
Delta time in open arm before/after self-admin0.10.10.3-0.60.3-0.40.3-0.1-0.0-0.3-0.0-0.10.0-0.0
Diff in mean of infusions in LGA sessions2.42.73.82.01.81.1-1.21.71.91.81.52.01.4-1.5
Extinction: sum of active levers before priming2.82.94.01.41.71.7-1.71.61.61.52.01.61.8-1.8
Active lever presses in extinction session 60.30.30.60.60.8-0.50.40.60.70.60.30.70.2-0.2
Delta distance traveled before/after self-admin0.50.62.0-0.6-0.3-0.20.6-1.4-0.4-0.6-1.3-0.4-0.70.8
Delta ambulatory time before/after self-admin0.30.41.4-0.50.10.10.4-1.2-0.2-0.5-1.1-0.2-0.50.5
Time in closed arm before self-admin0.20.30.8-0.30.3-0.80.9-0.30.00.1-0.3-0.1-0.70.7
Time in closed arm after self-admin0.20.20.60.60.80.20.1-0.10.60.7-0.10.6-0.20.2
Time in open arm before self-admin0.10.20.70.4-0.50.9-0.70.0-0.20.0-0.10.00.2-0.2
Time in open arm after self-admin0.10.10.4-0.6-0.3-0.0-0.2-0.2-0.4-0.5-0.1-0.40.1-0.1
Sum of active levers in priming session hrs 5-60.20.21.00.3-0.4-0.91.0-0.1-0.1-0.2-0.4-0.1-0.50.5
Time to tail flick, vehicle, before self-admin0.10.10.40.6-0.4-0.2-0.3-0.10.0-0.00.10.00.3-0.3
Time to tail flick, vehicle, after self-admin4.14.45.42.22.31.4-1.92.12.22.22.12.12.1-2.1
Time to tail flick, test, before self-admin0.70.71.60.81.20.1-0.60.81.00.91.00.90.8-0.8
Time to tail flick, test, after self-admin0.90.91.6-1.1-0.9-1.31.0-1.0-0.9-1.0-0.8-0.9-0.80.8
Delta time to tail flick, vehicle, before/after SA1.01.01.90.61.40.7-0.81.01.00.91.00.91.1-1.1
Delta time to tail flick, test, before/after SA1.00.91.6-0.9-1.3-0.90.8-0.8-1.0-0.8-0.9-0.9-0.90.9
Ambulatory time before self-admin2.93.04.82.11.21.1-1.72.11.71.72.21.61.7-1.7
Ambulatory time after self-admin1.51.72.61.61.31.3-1.40.91.51.21.01.41.3-1.3
Total heroin consumption0.30.31.4-0.00.0-1.21.1-0.50.0-0.1-0.50.1-0.50.5
Area under the delay curve0.30.30.90.30.40.9-0.50.90.30.40.60.30.4-0.5
Delay disc. indifference point, 0s delay0.00.00.20.10.10.20.10.4-0.0-0.10.4-0.10.1-0.1
Delay disc. indifference point, 16s delay0.20.20.70.40.60.6-0.10.80.50.70.40.5-0.00.0
Delay disc. indifference point, 2s delay0.10.10.3-0.2-0.2-0.40.60.1-0.5-0.4-0.1-0.5-0.30.3
Delay disc. indifference point, 24s delay0.50.41.10.40.40.6-0.81.00.50.70.90.50.6-0.6
Delay disc. indifference point, 4s delay0.00.00.20.2-0.0-0.10.30.4-0.1-0.10.1-0.1-0.10.1
Delay disc. indifference point, 8s delay0.40.41.50.10.11.2-0.90.80.20.30.70.10.6-0.6
Delay discount exponential model param0.30.30.9-0.4-0.4-0.90.6-0.9-0.3-0.5-0.6-0.3-0.40.4
Delay discount hyperbolic model param0.30.30.8-0.4-0.4-0.80.5-0.9-0.3-0.4-0.6-0.3-0.40.4
Fecal boli incidents, locomotor time 10.10.10.5-0.10.1-0.10.1-0.70.1-0.2-0.40.00.1-0.1
Change in fecal boli incidents, locomotor task0.20.20.5-0.5-0.1-0.30.5-0.4-0.3-0.2-0.6-0.4-0.70.7
Time >=10cm from walls, locomotor time 11.92.04.1-2.0-1.3-1.01.1-1.3-1.5-1.4-1.5-1.5-1.31.3
Bouts of movement, locomotor time 10.10.10.7-0.20.10.8-0.60.1-0.1-0.10.20.00.4-0.4
Total resting periods, locomotor time 10.40.41.00.10.61.0-0.90.40.30.30.60.50.8-0.8
Rest time, locomotor task time 10.20.30.70.50.50.0-0.30.20.40.20.50.70.8-0.8
Distance moved, locomotor task time 10.10.10.3-0.5-0.40.00.30.1-0.2-0.2-0.3-0.6-0.60.6
Vertical activity count, locomotor time 10.20.20.40.10.40.5-0.50.70.30.30.60.20.3-0.3
Time >=10cm from walls, locomotor time 23.23.44.9-2.2-1.7-1.61.9-1.7-1.9-1.8-1.9-1.8-1.91.9
Bouts of movement, locomotor time 20.80.81.70.60.81.3-0.91.30.71.00.90.80.7-0.7
Total resting periods, locomotor time 20.91.02.30.60.81.5-1.21.30.61.00.90.70.8-0.8
Rest time, locomotor task time 20.60.72.00.50.61.4-1.30.30.40.40.60.51.1-1.1
Distance moved, locomotor task time 20.10.10.1-0.4-0.1-0.40.30.3-0.0-0.10.0-0.2-0.30.3
Vertical activity count, locomotor time 20.80.81.80.80.80.5-0.61.30.90.91.41.00.8-0.8
Weight adjusted by age1.61.83.91.41.10.5-1.12.01.21.51.61.21.3-1.3
Seeking ratio, delayed vs. immediate footshock0.20.30.60.50.60.8-0.50.50.50.50.30.50.3-0.3
Locomotion in novel chamber0.40.51.9-0.3-0.3-1.41.10.0-0.3-0.2-0.2-0.4-0.90.9
Locomotion in novel chamber post-restriction0.00.00.2-0.1-0.2-0.40.2-0.2-0.2-0.3-0.0-0.30.0-0.0
Progressive ratio0.10.10.30.20.40.5-0.10.30.20.0-0.00.00.3-0.3
Food seeking constrained by brief footshock0.20.20.3-0.4-0.4-0.50.5-0.3-0.4-0.5-0.3-0.5-0.50.5
Seeking ratio, punishment vs. effort0.10.10.5-0.3-0.5-0.70.3-0.3-0.3-0.2-0.1-0.2-0.40.4
Run reversals in cocaine runway, females0.30.30.80.50.30.8-0.80.90.30.70.60.30.2-0.2
Run reversals in cocaine runway, males0.10.10.4-0.1-0.7-0.0-0.10.3-0.3-0.10.3-0.5-0.10.1
Latency to leave start box in cocaine runway0.50.51.70.40.61.3-1.00.40.50.70.50.50.6-0.6
Latency to leave start box in cocaine runway, F2.12.33.01.51.71.7-1.61.31.61.71.21.61.4-1.4
Latency to leave start box in cocaine runway, M0.70.71.1-0.9-1.0-0.40.6-0.6-1.0-0.7-0.6-1.1-0.90.9
Cd content in liver3.23.54.52.12.02.1-1.61.52.01.81.62.11.8-1.8
Co content in liver0.10.10.30.50.50.1-0.20.00.40.30.20.40.2-0.2
Cu content in liver0.10.10.40.30.30.7-0.10.40.20.40.40.20.2-0.2
Fe content in liver0.00.00.2-0.0-0.20.4-0.20.10.10.10.1-0.10.0-0.0
K content in liver6.46.48.6-2.3-2.4-2.82.9-2.3-2.4-2.3-2.5-2.4-2.72.7
Mg content in liver6.97.29.5-2.5-2.6-2.93.1-2.3-2.6-2.5-2.6-2.6-2.92.9
Mn content in liver14.016.017.8-3.9-4.0-3.84.2-3.9-4.0-3.8-4.2-3.9-4.24.2
Na content in liver0.60.71.5-0.8-1.0-0.60.9-0.6-1.0-1.2-0.6-0.9-0.40.4
Rb content in liver2.43.14.0-1.5-1.8-2.02.0-1.7-1.7-1.5-1.8-1.6-1.81.8
Se content in liver2.32.84.5-1.4-1.1-1.82.1-1.5-1.4-1.1-1.9-1.2-2.12.1
Sr content in liver0.30.30.8-0.3-0.3-0.90.6-0.5-0.3-0.1-0.6-0.3-0.70.8
Zn content in liver0.00.00.10.10.2-0.20.30.00.00.1-0.00.2-0.10.1