Hub : Genes

Zfp423

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability ENSRNOG00000014658 0.06 0.05 3.0e-03 0.01 -0 -0 0 1.2e-01 7.4e-01 7.1e-01 2.3e-01
2 Brain gene expression ENSRNOG00000014658 0.2 0.09 0.0e+00 0.26 0.26 0.25 0.27 2.6e-24 7.0e-24 6.8e-23 9.8e-25
3 Brain mRNA stability ENSRNOG00000014658 0.05 0.04 1.6e-03 0.03 0.02 0.01 0.04 3.5e-04 2.4e-03 2.0e-02 2.5e-04
4 IL gene expression ENSRNOG00000014658 0.26 0.12 4.6e-07 0.26 0.14 0.28 0.15 7.2e-07 4.1e-04 2.3e-07 1.7e-04
5 LHb alternative TSS ENSRNOT00000101491 0.18 0.11 1.9e-03 0.07 0.02 0.07 0.07 1.0e-02 1.1e-01 1.1e-02 9.5e-03
6 LHb alternative TSS ENSRNOT00000101895 0.19 0.11 1.1e-03 0.07 0.03 0.1 0.07 8.9e-03 6.7e-02 2.5e-03 1.1e-02
7 Liver mRNA stability ENSRNOG00000014658 0.06 0.04 5.9e-07 0.06 0.05 0.04 0.05 3.4e-07 7.0e-06 2.3e-05 1.3e-06
8 NAcc gene expression ENSRNOG00000014658 0.09 0.06 3.5e-06 0.06 0.07 0.07 0.07 1.6e-05 3.2e-06 9.5e-06 3.6e-06
9 OFC gene expression ENSRNOG00000014658 0.53 0.16 4.7e-13 0.36 0.4 0.4 0.4 2.0e-09 1.4e-10 1.2e-10 1.7e-10
10 OFC mRNA stability ENSRNOG00000014658 0.2 0.11 9.3e-05 0.22 0.15 0.18 0.21 6.7e-06 2.3e-04 5.2e-05 1.1e-05
11 PL alternative TSS ENSRNOT00000020028 0.05 0.03 2.9e-04 0.03 0.03 0.02 0.03 3.4e-03 1.4e-03 7.6e-03 4.7e-03
12 PL alternative TSS ENSRNOT00000101491 0.04 0.03 1.3e-03 0.02 0.03 0.02 0.02 9.9e-03 2.3e-03 1.6e-02 1.4e-02
13 PL alternative TSS ENSRNOT00000101491 0.08 0.05 9.9e-07 0.05 0.06 0.03 0.05 1.8e-04 1.3e-05 1.3e-03 5.7e-05
14 PL alternative TSS ENSRNOT00000101895 0.09 0.05 1.8e-07 0.05 0.08 0.04 0.07 9.2e-05 1.8e-06 2.5e-04 8.3e-06
15 PL gene expression ENSRNOG00000014658 0.26 0.11 0.0e+00 0.22 0.26 0.26 0.26 1.3e-16 4.0e-20 7.7e-20 7.1e-20
16 PL mRNA stability ENSRNOG00000014658 0.18 0.11 1.5e-05 0.06 0.04 0.05 0.06 1.1e-05 1.0e-03 1.8e-04 5.0e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
BMI with tail1.55.06.12.42.51.62.3-2.42.41.92.42.41.82.3-2.3-2.42.42.21.8
BMI without tail0.00.10.40.6-0.1-0.4-0.3-0.60.4-0.40.2-0.0-0.2-0.20.30.2-0.20.0-0.1
Body weight0.93.65.01.71.72.01.9-1.82.02.01.81.82.21.8-1.8-1.91.92.02.2
Epididymis fat weight0.51.23.6-0.10.61.91.2-0.20.61.30.40.61.71.1-1.1-1.11.11.01.7
Glucose0.20.30.8-0.4-0.9-0.2-0.60.3-0.3-0.4-0.7-0.9-0.2-0.70.70.7-0.7-0.5-0.2
Heart weight0.81.12.91.71.5-0.10.9-1.51.20.71.41.20.01.0-0.9-1.01.00.90.1
Left kidney weight0.10.20.3-0.0-0.4-0.6-0.50.1-0.2-0.1-0.2-0.4-0.2-0.60.60.5-0.6-0.4-0.1
Right kidney weight0.10.20.40.50.50.10.6-0.50.50.60.50.50.70.4-0.4-0.40.40.40.6
Tail length1.75.26.9-1.9-2.6-1.9-2.52.0-2.1-2.1-2.3-2.5-1.8-2.62.62.6-2.6-2.2-1.8
Length with tail0.00.20.5-0.5-0.50.6-0.00.4-0.10.5-0.4-0.30.7-0.20.20.2-0.20.10.7
Length without tail2.96.39.01.62.33.02.7-1.72.13.02.12.32.92.6-2.6-2.62.62.62.9
Liver weight, left0.40.61.4-0.40.31.21.00.4-0.01.0-0.00.51.20.8-0.8-0.70.80.41.1
Liver weight, right0.60.92.2-0.10.61.51.1-0.00.41.10.40.71.51.0-1.0-1.01.00.91.4
Parametrial fat weight0.10.10.4-0.40.10.20.60.10.00.6-0.20.20.70.3-0.3-0.30.30.00.7
Retroperitoneal fat weight1.23.97.00.21.52.72.6-0.31.02.20.91.62.62.2-2.3-2.22.31.62.6
Intraocular pressure4.36.18.32.32.92.02.6-2.22.32.22.62.71.82.8-2.8-2.82.82.41.8
Extensor digitorum longus weight0.10.31.01.0-0.10.5-0.3-1.00.90.40.50.00.5-0.20.20.1-0.10.60.5
Soleus weight0.00.10.2-0.5-0.0-0.00.30.5-0.4-0.1-0.30.00.00.1-0.2-0.10.1-0.2-0.0
Tibialis anterior weight0.51.83.81.91.50.81.1-1.81.61.11.71.50.81.2-1.2-1.21.21.40.8
Tibia length0.10.31.01.0-0.10.5-0.3-1.00.90.10.5-0.00.4-0.20.20.1-0.10.60.4
Number of licking bursts0.50.61.0-1.0-0.7-0.7-0.70.9-0.9-0.7-0.8-0.8-0.8-0.70.70.7-0.7-0.8-0.8
Food consumed during 24 hour testing period4.55.49.3-3.0-2.7-1.3-2.03.0-2.7-1.7-2.8-2.8-1.2-2.32.32.4-2.3-2.3-1.2
Times rat made contact with spout0.30.40.60.1-0.4-0.8-0.80.1-0.3-0.7-0.3-0.6-0.8-0.70.70.7-0.7-0.5-0.8
Mean time between licks in bursts0.10.20.70.00.3-0.80.1-0.0-0.2-0.50.10.3-0.80.1-0.1-0.00.1-0.4-0.8
Mean num. licks in bursts0.10.21.01.00.4-0.2-0.0-0.80.60.10.60.3-0.10.0-0.0-0.10.00.3-0.1
Std. dev. time between licks in bursts0.60.71.3-0.6-0.7-1.1-0.80.6-0.7-1.1-0.7-0.7-1.1-0.80.80.8-0.8-1.0-1.1
Water consumed over 24 hours2.42.84.1-1.9-1.8-1.2-1.71.8-1.8-1.4-1.9-2.0-1.2-1.81.71.8-1.8-1.6-1.2
Indifference point 0 sec0.20.41.10.20.80.31.0-0.30.30.40.40.80.30.9-0.9-0.80.90.40.4
Indifference point AUC0.60.71.8-1.3-1.2-0.0-0.81.0-0.8-0.6-1.1-1.0-0.1-0.90.80.8-0.8-0.7-0.1
Indifference point function ln k0.60.92.01.41.4-0.00.9-1.10.90.51.21.20.11.0-1.0-1.01.00.80.1
Indifference point function log k0.60.92.01.41.4-0.00.9-1.10.90.51.21.20.11.0-1.0-1.01.00.80.1
Delay discounting total patch changes 0 sec0.40.71.50.30.90.61.2-0.40.50.70.61.00.61.1-1.1-1.01.10.60.6
Delay discounting total patch changes 12 sec0.50.62.6-1.6-0.7-0.40.01.4-1.2-0.4-1.2-0.6-0.2-0.30.30.4-0.3-0.9-0.2
Delay discounting total patch changes 18 sec1.21.64.1-2.0-1.4-0.4-0.81.8-1.6-1.0-1.7-1.3-0.6-1.11.01.1-1.0-1.3-0.5
Delay discounting total patch changes 24 sec0.81.02.7-1.6-1.0-0.6-0.41.5-1.4-0.9-1.4-0.9-0.6-0.70.60.7-0.7-1.2-0.6
Delay discounting total patch changes 6 sec0.20.20.8-0.9-0.5-0.4-0.20.7-0.6-0.4-0.7-0.4-0.3-0.30.30.4-0.3-0.6-0.3
Delay discounting time to switch 0 sec0.10.10.3-0.3-0.1-0.6-0.00.4-0.4-0.2-0.3-0.1-0.3-0.10.10.2-0.1-0.4-0.3
Delay discounting water rate 0 sec0.10.10.50.1-0.20.7-0.1-0.20.30.30.1-0.10.6-0.00.0-0.0-0.00.30.6
Delay discounting water rate 12 sec1.01.53.2-0.3-1.0-1.4-1.60.5-0.9-1.5-0.7-1.1-1.8-1.31.31.3-1.3-1.1-1.8
Delay discounting water rate 18 sec3.85.08.5-0.5-1.9-2.9-2.80.8-1.4-2.3-1.3-2.2-2.6-2.62.72.6-2.6-2.0-2.7
Delay discounting water rate 24 sec0.30.51.50.2-0.2-1.2-0.80.0-0.3-0.8-0.1-0.4-1.0-0.70.70.7-0.7-0.5-1.1
Delay discounting water rate 6 sec3.14.55.9-1.9-2.4-1.7-2.21.9-2.0-2.0-2.2-2.4-1.6-2.42.42.4-2.4-2.1-1.7
Locomotor activity0.30.51.10.90.20.70.5-0.91.00.70.60.31.10.4-0.4-0.40.40.71.0
Locomotor testing distance0.30.41.00.60.30.90.6-0.50.70.70.40.41.00.6-0.6-0.60.60.61.0
Locomotor testing rearing0.60.92.9-1.7-1.0-0.4-0.31.5-1.3-0.6-1.4-0.9-0.4-0.60.50.6-0.6-1.1-0.4
Light reinforcement 112.823.529.8-5.1-5.5-3.8-4.65.3-5.1-4.4-5.4-5.4-3.5-5.15.15.1-5.1-5.0-3.5
Light reinforcement 29.512.616.9-3.7-4.1-2.5-3.53.8-3.7-3.1-4.0-4.1-2.3-3.83.83.8-3.8-3.6-2.4
Reaction time number correct0.50.71.71.31.00.30.6-1.31.10.41.10.90.10.8-0.8-0.90.80.80.1
Reaction time mean minus median1.11.43.11.81.11.00.8-1.51.51.11.41.11.11.0-0.9-1.01.01.31.1
Reaction time mean minus median AUC1.72.22.91.71.41.51.3-1.61.71.51.61.41.51.3-1.3-1.41.31.71.6
Reaction time num false alarms3.85.27.61.72.61.92.8-1.71.92.22.12.61.92.7-2.7-2.72.72.11.9
Reaction time num false alarms AUC2.63.75.61.62.31.22.4-1.51.61.81.82.31.32.3-2.3-2.32.31.71.3
Reaction time trials correct on left0.50.71.71.31.00.30.6-1.31.10.41.10.90.10.8-0.8-0.90.80.80.1
Reaction time trials on left0.60.92.01.41.10.40.7-1.41.20.61.21.00.21.0-0.9-1.01.01.00.2
Reaction time mean3.54.76.22.52.41.81.9-2.32.32.32.52.31.92.1-2.0-2.12.12.41.9
Reaction time mean AUC3.74.96.22.42.41.92.0-2.22.32.32.52.32.02.1-2.1-2.22.12.42.0
Median of all reaction times3.24.45.82.32.41.71.9-2.12.12.22.42.31.82.0-2.0-2.12.02.31.8
Reaction time omissions2.43.24.11.71.81.71.8-1.71.82.01.81.91.81.8-1.8-1.81.81.81.7
Reaction time false alarm rate1.01.52.80.61.40.81.7-0.60.71.30.91.51.01.5-1.5-1.41.51.01.1
Reaction time premature initiation rate4.15.59.8-3.1-2.4-1.8-1.73.1-3.0-2.1-2.9-2.3-1.7-2.12.02.1-2.1-2.7-1.7
Reaction time premature initiations1.72.44.1-2.0-1.5-1.2-1.12.0-2.0-1.5-1.9-1.5-1.3-1.31.21.3-1.3-1.8-1.3
Std. dev. reaction times1.72.43.01.71.51.61.3-1.61.71.61.71.51.51.4-1.4-1.51.41.71.6
Reaction time trials completed0.60.92.01.41.10.40.7-1.41.20.61.21.00.21.0-0.9-1.01.01.00.2
Reaction time trials AUC0.71.02.11.41.10.50.7-1.41.20.61.31.10.21.0-1.0-1.01.01.00.2
Social response proportion0.50.61.10.70.70.80.6-0.70.81.10.80.80.90.6-0.6-0.60.60.91.0
Social responses0.30.41.0-0.40.70.31.00.3-0.10.70.10.80.60.8-0.8-0.70.80.20.6
Social time0.50.71.2-0.5-0.8-1.1-0.90.6-0.7-0.8-0.6-0.7-0.8-1.01.01.0-1.0-0.9-0.8
Conditioned locomotion0.00.00.00.1-0.10.1-0.2-0.00.1-0.0-0.00.00.2-0.10.10.1-0.10.00.2
Cocaine response after cond. corrected3.74.26.20.71.82.42.3-1.01.52.31.52.02.52.2-2.3-2.22.22.02.5
Cocaine response after cond. not corrected3.13.55.70.81.62.42.0-1.01.42.21.41.82.42.0-2.0-2.02.01.92.4
Cocaine response before conditioning1.82.23.6-0.7-1.5-1.5-1.90.8-1.1-1.7-1.1-1.5-1.6-1.71.71.7-1.7-1.3-1.6
Saline control response1.01.35.1-2.3-1.2-0.2-0.32.0-1.7-0.6-1.7-1.1-0.2-0.70.70.8-0.7-1.2-0.2
Condit. Reinf. active minus inactive responses0.20.20.30.40.40.50.5-0.50.50.50.50.40.50.5-0.5-0.50.50.50.5
Condit. Reinf. active-inactive response ratio0.70.71.61.10.50.90.3-1.31.30.91.00.61.00.4-0.4-0.50.51.11.0
Condit. Reinf. active responses0.10.10.20.10.10.50.4-0.10.20.20.10.20.50.3-0.3-0.30.30.20.5
Condit. Reinf. inactive responses0.20.30.7-0.20.30.70.90.3-0.00.4-0.10.30.60.6-0.7-0.60.60.20.6
Condit. Reinf. lever presses0.60.91.10.60.90.91.1-0.70.90.90.81.01.01.0-1.0-1.01.00.91.0
Condit. Reinf. lever reinforcers received0.30.40.60.50.50.80.7-0.50.60.60.50.50.80.6-0.6-0.60.60.60.8
Pavlov. Cond. lever latency0.60.81.10.70.81.10.9-0.80.91.00.90.81.00.9-0.9-0.90.91.01.0
Pavlov. Cond. magazine entry latency0.10.10.3-0.5-0.2-0.1-0.10.5-0.4-0.1-0.3-0.2-0.1-0.10.10.1-0.1-0.2-0.1
Pavlov. Cond. change in total contacts0.20.30.7-0.1-0.3-0.8-0.70.1-0.3-0.6-0.2-0.2-0.8-0.50.50.5-0.5-0.5-0.8
Pavlov. Cond. index score0.10.10.2-0.2-0.2-0.5-0.40.2-0.3-0.4-0.2-0.2-0.5-0.30.30.3-0.3-0.3-0.5
Pavlov. Cond. latency score0.10.10.1-0.2-0.2-0.4-0.30.2-0.3-0.3-0.2-0.2-0.4-0.30.30.3-0.3-0.3-0.4
Pavlov. Cond. lever contacts0.91.31.5-1.1-1.1-1.2-1.11.1-1.2-1.2-1.1-1.1-1.1-1.11.11.1-1.1-1.2-1.1
Pavlov. Cond. magazine entry number0.00.00.0-0.0-0.1-0.1-0.1-0.0-0.0-0.1-0.1-0.2-0.1-0.10.10.1-0.1-0.1-0.1
Pavlov. Cond. intertrial magazine entries0.60.71.0-0.8-1.0-0.7-0.70.9-0.9-0.9-1.0-1.0-0.7-0.80.80.9-0.8-1.0-0.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.3-0.2-0.5-0.40.3-0.4-0.4-0.2-0.2-0.5-0.30.30.3-0.3-0.3-0.5
Pavlov. Cond. response bias0.20.30.4-0.5-0.6-0.5-0.60.5-0.6-0.6-0.6-0.5-0.5-0.60.60.6-0.6-0.6-0.5
Conditioned reinforcement - actives1.21.21.80.71.01.31.3-0.60.81.10.81.11.11.3-1.3-1.31.31.01.1
Conditioned reinforcement - inactives0.91.12.40.41.11.11.6-0.10.40.90.41.00.81.4-1.5-1.41.40.70.8
Conditioned locomotion0.00.00.10.00.20.10.4-0.00.10.20.10.20.30.2-0.2-0.20.20.10.3
Intermittent access intake day 1-15 change2.92.94.9-2.2-1.9-0.9-1.62.2-2.0-1.5-2.0-1.9-1.2-1.61.61.6-1.6-1.7-1.2
Intermittent access intake escalation4.44.36.9-2.6-2.3-1.1-2.02.6-2.4-1.8-2.5-2.3-1.4-2.02.02.0-2.0-2.1-1.4
Intermittent access intake escalation 23.53.56.0-2.4-1.9-1.3-1.52.4-2.3-1.7-2.3-1.9-1.7-1.61.61.6-1.6-2.0-1.7
Intermitt. access day 1 inactive lever presses0.10.10.40.20.3-0.60.20.1-0.2-0.30.10.3-0.60.2-0.2-0.20.2-0.2-0.6
Intermitt. access day 15 inactive lever presses0.80.91.90.21.01.01.4-0.10.41.10.50.90.91.2-1.2-1.21.20.70.9
Intermitt. access escalation Index0.30.30.6-0.8-0.7-0.1-0.50.5-0.5-0.5-0.7-0.6-0.3-0.40.40.4-0.4-0.5-0.3
Intermittent access day 1 total infusions3.84.34.82.02.01.92.2-2.02.12.12.02.12.02.1-2.1-2.22.12.12.0
Intermittent access day 15 total infusions0.10.10.6-0.10.10.80.30.00.20.40.10.10.60.3-0.3-0.30.30.30.6
Intermittent access terminal intake (last 3 days)0.50.51.20.00.51.10.9-0.10.40.70.30.50.90.8-0.8-0.80.80.60.9
Intermittent access total infusions0.60.61.30.40.51.10.9-0.40.60.80.50.61.10.8-0.8-0.80.80.81.1
Intermittent access day 1 locomotion0.70.71.71.30.70.50.5-1.21.20.61.10.80.70.6-0.5-0.60.60.90.7
Intermittent access day 15 total locomotion1.11.22.11.00.71.50.7-1.11.31.21.20.81.40.8-0.8-0.90.81.41.4
Intermittent access total locomotion1.21.42.51.20.81.60.8-1.21.41.21.20.91.50.9-0.9-1.00.91.51.5
Intermittent access standard deviation0.60.61.1-0.7-0.5-1.0-0.70.7-0.9-0.9-0.7-0.6-1.0-0.70.70.7-0.7-0.9-1.0
Cocaine induced anxiety1.01.23.4-0.31.10.91.80.20.10.90.21.10.91.5-1.6-1.41.50.40.9
Post-drug Anxiety0.50.61.50.10.80.61.2-0.10.30.70.30.80.71.0-1.0-1.01.00.50.7
Baseline Anxiety0.30.30.70.5-0.40.6-0.5-0.50.60.50.3-0.40.8-0.50.50.4-0.40.50.8
Lifetime Intake0.50.61.30.20.51.11.0-0.20.50.80.30.51.10.8-0.9-0.80.80.71.1
Incentive Sensitization - Responses0.00.00.1-0.30.20.20.10.3-0.3-0.0-0.10.1-0.30.3-0.3-0.20.3-0.0-0.3
Incentive Sensitization - Breakpoint0.10.10.2-0.40.10.1-0.00.4-0.3-0.1-0.2-0.0-0.40.2-0.2-0.10.1-0.1-0.4
Progressive ratio test 1 active lever presses2.42.53.31.61.31.81.4-1.51.71.51.61.41.81.4-1.4-1.51.41.81.8
Progressive ratio test 1 breakpoint1.61.72.31.41.01.51.1-1.31.41.21.31.11.51.1-1.1-1.21.21.51.5
Progressive ratio test 1 inactive lever presses0.10.10.20.40.30.30.4-0.20.20.20.30.30.20.4-0.4-0.40.40.30.2
Progressive ratio test 2 active lever presses0.70.81.40.70.91.20.8-0.70.80.90.90.80.80.9-1.0-1.01.01.00.8
Progressive ratio test 2 breakpoint1.11.22.10.81.01.41.0-0.70.91.21.00.91.11.1-1.2-1.21.21.21.1
Progressive ratio test 2 inactive lever presses2.93.34.41.31.82.02.0-1.31.61.91.61.81.82.1-2.1-2.12.11.81.8
Total sessions with >9 infusions0.50.60.70.90.80.70.7-0.80.80.60.90.80.60.8-0.8-0.80.80.80.6
Short access day 1 total inactive lever presses0.10.20.4-0.6-0.60.3-0.10.6-0.4-0.2-0.6-0.40.3-0.20.10.2-0.2-0.20.3
Short access day 10 total inactive lever presses1.01.11.9-1.3-0.7-1.4-0.61.3-1.3-1.0-1.2-0.9-1.1-0.80.80.9-0.8-1.3-1.1
Short access day 1 total infusions1.71.82.31.21.31.41.4-1.21.31.21.31.41.11.5-1.5-1.51.51.41.1
Short access day 10 total infusions0.70.71.70.20.41.31.1-0.10.40.90.30.61.30.9-1.0-0.90.90.71.3
Short access total infusions0.30.30.80.20.20.90.7-0.10.30.60.20.30.90.6-0.6-0.60.60.50.9
Short access day 1 locomotion2.52.63.01.51.61.71.5-1.51.71.51.61.71.61.7-1.7-1.71.71.71.6
Short access day 10 total locomotion0.20.20.40.60.60.20.3-0.60.50.30.60.50.20.4-0.4-0.40.40.50.2
Short access total locomotion1.01.01.41.11.10.80.9-1.11.10.81.21.10.81.0-1.0-1.01.01.10.8
Compulsive drug intake2.62.65.1-1.1-1.2-2.3-1.51.2-1.6-1.8-1.3-1.3-2.1-1.51.61.6-1.6-1.8-2.1
One hour access (0.3 mA shock)0.30.40.8-0.60.40.90.90.5-0.20.6-0.20.30.70.8-0.8-0.70.80.20.7
One hour access (shock baseline)2.02.44.50.51.32.11.8-0.71.11.70.91.31.91.7-1.8-1.71.71.41.9
Number of responses in last shaping day4.74.86.31.92.31.82.5-1.92.02.22.12.32.02.5-2.5-2.42.52.12.0
Context. condit. distance diff. score3.03.76.90.72.21.62.6-0.91.12.01.42.21.62.4-2.5-2.42.41.51.6
Locomotion velocity, session 10.30.30.6-0.7-0.8-0.1-0.60.6-0.5-0.3-0.7-0.6-0.2-0.60.60.6-0.6-0.4-0.3
Locomotion distance, session 10.20.30.5-0.50.30.70.70.4-0.10.5-0.00.40.70.6-0.6-0.50.60.30.7
Locomotion velocity, session 20.00.00.2-0.4-0.00.20.10.3-0.20.1-0.10.10.10.1-0.1-0.10.1-0.00.1
Locomotion distance, session 20.60.81.4-0.10.71.21.2-0.10.41.00.40.81.21.0-1.1-1.01.00.81.2
Locomotion velocity, session 31.51.72.81.61.31.11.2-1.71.61.21.41.31.01.3-1.3-1.31.31.31.0
Locomotion distance, session 30.20.20.80.50.4-0.8-0.1-0.40.1-0.60.30.4-0.90.1-0.0-0.00.0-0.2-0.9
Stereotopy head waving bouts, day 30.20.30.80.90.7-0.00.5-0.70.60.20.70.50.10.5-0.5-0.50.50.40.1
Stereotopy head waving duration, day 30.70.91.11.01.00.61.0-1.00.90.91.00.90.71.0-1.0-1.01.00.90.7
Locomotion velocity, session 70.50.61.30.21.10.31.2-0.30.30.70.60.90.31.1-1.1-1.01.10.40.3
Locomotion distance, session 70.10.20.8-0.9-0.2-0.00.30.8-0.7-0.1-0.6-0.20.00.1-0.1-0.10.1-0.40.0
Stereotopy head waving bouts, day 70.30.31.01.00.4-0.9-0.2-0.90.4-0.40.60.4-0.9-0.00.10.0-0.0-0.1-0.9
Stereotopy head waving duration, day 70.91.12.60.3-0.7-1.6-1.3-0.1-0.4-1.3-0.3-0.7-1.6-1.11.11.1-1.1-0.9-1.6
Locomotion velocity, session 81.72.03.8-0.21.11.81.9-0.10.51.80.51.21.81.7-1.7-1.61.71.01.8
Locomotion distance, session 81.42.14.9-0.21.51.42.2-0.00.41.50.71.51.41.9-2.0-1.81.90.91.4
Degree of sensitization distance0.30.31.0-0.7-0.20.90.60.6-0.20.6-0.4-0.11.00.3-0.4-0.30.30.11.0
Degree of sensitization stereotypy0.30.31.41.20.5-0.5-0.1-1.10.7-0.10.80.6-0.60.1-0.1-0.10.10.2-0.6
Condit. Reinf. active minus inactive responses0.30.30.90.50.9-0.80.4-0.2-0.0-0.50.50.8-0.90.5-0.5-0.50.5-0.1-0.9
Condit. Reinf. active-inactive response ratio0.80.91.70.31.30.51.3-0.30.40.70.81.30.41.3-1.3-1.21.20.70.4
Condit. Reinf. active responses1.01.23.70.0-0.4-1.8-1.00.3-0.8-1.6-0.4-0.5-1.9-0.80.90.9-0.9-1.1-1.9
Condit. Reinf. inactive responses5.56.69.0-1.1-2.6-2.8-3.01.3-1.8-2.9-2.1-2.7-2.8-2.92.92.9-2.9-2.5-2.8
Incentive salience index mean1.61.94.5-0.8-0.6-2.0-1.11.0-1.4-1.8-0.9-0.7-2.1-1.01.11.1-1.1-1.5-2.1
Condit. Reinf. lever presses3.64.96.9-1.6-1.9-2.5-2.31.8-2.2-2.6-1.9-2.0-2.6-2.22.22.2-2.2-2.3-2.6
Time in familiar zone, hab. session 11.41.32.2-0.9-0.8-1.3-1.21.1-1.2-1.1-0.9-0.9-1.5-1.01.11.1-1.1-1.2-1.5
Time in novel zone, hab. session 10.90.91.91.40.80.70.7-1.41.30.71.10.80.90.7-0.7-0.80.71.00.9
Total zone transitions, hab. session 10.30.51.00.20.50.90.8-0.30.50.80.40.61.00.7-0.7-0.70.70.61.0
Total locomotion distance, hab. session 10.91.42.20.51.01.41.3-0.70.91.20.81.11.51.2-1.3-1.21.31.11.5
Locomotion velocity, hab. session 10.91.32.40.40.91.51.3-0.50.81.20.71.11.51.2-1.2-1.21.21.11.5
Time in familiar zone, hab. session 22.12.23.4-1.8-1.5-1.4-1.11.8-1.8-1.4-1.7-1.4-1.3-1.31.21.3-1.3-1.7-1.3
Time in novel zone, hab. session 24.95.06.42.42.32.12.0-2.52.52.12.52.22.12.1-2.1-2.22.12.52.1
Total zone transitions, hab. session 20.10.10.3-0.5-0.1-0.3-0.00.5-0.4-0.3-0.4-0.1-0.2-0.10.10.1-0.1-0.4-0.2
Total locomotion distance, hab. session 20.20.30.80.00.30.80.8-0.10.30.60.20.50.90.6-0.6-0.60.60.50.9
Locomotion velocity, hab. session 20.10.20.7-0.10.10.70.50.00.20.40.00.30.80.3-0.4-0.30.30.30.8
Novel to familiar place preference ratio1.31.41.91.21.40.91.1-1.31.31.11.41.31.01.2-1.1-1.21.11.21.0
Novelty place preference1.21.31.61.11.21.01.1-1.21.21.21.31.21.11.1-1.1-1.11.11.21.1
Time in novel zone, NPP test1.01.01.61.31.10.70.7-1.31.20.91.31.00.80.8-0.8-0.90.81.10.8
Total zone transitions, NPP test0.10.10.3-0.20.00.60.50.10.10.3-0.00.20.50.3-0.4-0.30.40.20.5
Total locomotion distance, NPP test0.10.20.40.60.30.40.4-0.60.60.30.40.40.50.4-0.4-0.40.40.40.5
Locomotion velocity, NPP test0.10.20.50.10.20.60.5-0.20.30.40.20.40.70.4-0.4-0.40.40.30.7
Pavlov. Cond. lever latency0.10.10.2-0.40.00.40.40.3-0.10.2-0.2-0.00.40.3-0.3-0.20.30.10.4
Pavlov. Cond. magazine entry latency0.10.10.60.80.4-0.2-0.1-0.70.50.00.60.2-0.20.1-0.0-0.10.10.3-0.2
Pavlov. Cond. change in total contacts1.11.22.2-0.2-1.1-1.2-1.50.3-0.6-1.1-0.7-1.1-1.1-1.41.41.3-1.4-0.9-1.1
Pavlov. Cond. index score0.10.10.50.70.4-0.3-0.1-0.60.4-0.00.50.2-0.20.1-0.0-0.10.10.2-0.2
Pavlov. Cond. latency score0.00.10.20.40.4-0.10.1-0.40.30.10.40.3-0.10.2-0.1-0.20.20.2-0.1
Pavlov. Cond. lever contacts0.10.10.40.6-0.1-0.3-0.5-0.50.3-0.20.2-0.1-0.3-0.30.40.3-0.30.0-0.3
Pavlov. Cond. magazine entry number0.20.20.6-0.8-0.10.60.50.7-0.30.3-0.40.10.60.4-0.4-0.30.4-0.00.6
Pavlov. Cond. intertrial magazine entries0.00.00.10.30.1-0.10.1-0.10.0-0.30.00.1-0.20.1-0.1-0.10.1-0.1-0.2
Pavlov. Cond. lever-magazine prob. diff.0.20.20.70.90.60.10.2-0.80.70.30.70.40.10.3-0.3-0.30.30.50.1
Pavlov. Cond. response bias0.30.41.51.20.0-0.7-0.7-1.00.6-0.40.5-0.1-0.6-0.50.50.4-0.50.1-0.6
Bone: apparent density1.62.73.5-0.9-1.6-1.7-1.91.0-1.3-1.8-1.4-1.7-1.8-1.81.91.8-1.8-1.6-1.8
Bone surface1.12.02.9-0.4-1.3-1.6-1.70.6-0.9-1.6-1.1-1.4-1.6-1.61.61.6-1.6-1.4-1.6
Bone volume2.23.85.6-0.8-2.0-2.0-2.41.1-1.4-2.1-1.6-2.0-2.0-2.32.32.2-2.3-1.9-2.0
Bone: connectivity density1.82.84.1-1.1-1.4-2.0-1.71.3-1.6-1.9-1.4-1.5-2.0-1.71.71.7-1.7-1.8-2.0
Bone: cortical apparent density0.20.31.40.20.3-1.2-0.1-0.0-0.3-0.60.00.1-1.1-0.10.10.1-0.1-0.5-1.1
Bone: cortical area0.20.20.4-0.1-0.6-0.4-0.60.3-0.4-0.6-0.5-0.6-0.4-0.60.60.6-0.6-0.5-0.4
Bone: cortical porosity0.10.10.20.10.10.50.3-0.10.20.20.10.20.50.2-0.3-0.30.30.20.5
Bone: cortical porosity0.00.00.20.0-0.3-0.1-0.20.0-0.1-0.4-0.2-0.2-0.1-0.20.20.2-0.2-0.2-0.1
Bone: cortical thickness0.00.00.20.5-0.0-0.2-0.2-0.20.1-0.10.1-0.1-0.2-0.10.10.1-0.1-0.0-0.2
Bone: cortical thickness0.10.10.40.00.30.50.5-0.00.20.60.10.30.50.4-0.4-0.40.40.30.5
Bone: cortical tissue density0.20.31.40.20.3-1.2-0.1-0.0-0.3-0.60.00.1-1.2-0.00.10.1-0.1-0.6-1.2
Bone: elastic displacement0.00.00.10.10.2-0.20.2-0.10.00.10.10.3-0.20.2-0.2-0.20.2-0.0-0.2
Bone: elastic work0.00.00.10.4-0.0-0.1-0.1-0.20.1-0.20.10.0-0.1-0.10.10.1-0.1-0.0-0.1
Bone: endosteal estimation0.20.41.2-0.00.31.10.7-0.10.30.80.20.41.00.6-0.7-0.60.60.61.0
Bone: endosteal perimeter0.20.41.0-0.30.41.00.90.20.10.60.10.50.90.7-0.8-0.70.70.40.9
Bone: final force0.61.02.0-0.5-1.4-0.3-1.30.7-0.6-0.9-1.0-1.4-0.4-1.31.31.3-1.3-0.7-0.4
Bone: final moment0.40.61.2-0.4-1.1-0.2-1.00.5-0.4-0.7-0.7-1.1-0.2-1.11.01.0-1.0-0.5-0.2
Bone: marrow area0.20.51.30.00.41.10.8-0.10.40.80.30.51.00.7-0.7-0.70.70.71.0
Bone: maximum diameter0.10.20.30.40.50.30.5-0.30.30.20.40.50.30.5-0.5-0.50.50.40.3
Bone: maximum force0.10.10.3-0.2-0.60.3-0.40.3-0.2-0.2-0.4-0.60.3-0.50.40.4-0.4-0.10.3
Bone: maximum moment0.00.10.1-0.0-0.30.3-0.20.1-0.0-0.0-0.2-0.30.3-0.20.20.2-0.20.00.3
Bone: minimum diameter0.50.91.5-0.8-1.2-0.4-1.10.9-0.9-0.8-1.1-1.2-0.5-1.21.11.1-1.1-0.9-0.5
Bone: periosteal estimation0.00.00.2-0.2-0.20.40.10.3-0.10.0-0.3-0.20.3-0.00.00.0-0.0-0.00.3
Bone: periosteal perimeter0.00.00.1-0.00.20.30.40.1-0.0-0.0-0.00.20.20.3-0.3-0.30.30.00.2
Bone: post-yield work0.10.10.4-0.4-0.10.60.20.4-0.20.4-0.2-0.10.60.1-0.1-0.10.10.20.6
Bone: stiffness0.10.20.90.0-0.50.9-0.10.00.30.3-0.2-0.50.9-0.30.20.2-0.20.30.9
Bone: tissue strength0.00.00.10.00.10.1-0.10.0-0.0-0.30.1-0.00.0-0.10.10.1-0.10.10.1
Bone: trabecular number2.13.35.0-0.7-1.6-2.2-2.10.9-1.4-2.2-1.4-1.7-2.2-2.02.02.0-2.0-1.8-2.2
Bone: trabecular spacing2.32.93.80.81.71.82.0-1.01.31.81.41.81.91.9-1.9-1.91.91.71.9
Bone: trabecular thickness2.43.05.0-0.6-2.0-1.5-2.20.7-1.0-1.6-1.4-2.1-1.5-2.22.22.1-2.1-1.5-1.5
Bone: trabecular tissue density1.01.52.80.80.91.61.1-0.91.21.41.00.91.71.1-1.1-1.11.11.31.7
Breakpoint value in progressive ratio session1.01.14.6-1.1-0.32.00.90.70.01.2-0.4-0.02.20.5-0.6-0.50.60.62.0
Distance traveled before self-admin1.71.82.71.31.11.41.1-1.51.61.31.41.21.61.1-1.1-1.21.11.61.6
Distance traveled after self-admin0.20.20.60.7-0.10.3-0.4-0.70.70.10.4-0.10.4-0.30.30.2-0.30.40.3
Delta time in closed arm before/after self-admin0.90.91.51.21.10.50.8-1.21.10.71.21.10.31.0-0.9-1.01.01.00.4
Delta time in open arm before/after self-admin1.11.02.8-1.7-1.40.4-0.51.6-1.1-0.3-1.5-1.30.5-0.80.80.8-0.8-0.70.5
Diff in mean of infusions in LGA sessions0.50.61.7-0.60.31.01.10.5-0.00.9-0.10.41.30.8-0.8-0.70.80.41.3
Extinction: sum of active levers before priming3.63.64.31.52.01.82.0-1.61.82.01.82.01.82.1-2.1-2.12.11.91.8
Active lever presses in extinction session 60.10.10.4-0.0-0.1-0.5-0.40.0-0.2-0.2-0.0-0.1-0.5-0.30.30.3-0.3-0.2-0.6
Delta distance traveled before/after self-admin1.01.11.6-0.6-1.1-0.9-1.30.7-0.8-1.0-0.9-1.1-1.1-1.21.21.2-1.2-1.0-1.1
Delta ambulatory time before/after self-admin2.12.32.8-1.1-1.5-1.5-1.71.2-1.4-1.5-1.4-1.6-1.6-1.61.61.6-1.6-1.5-1.6
Time in closed arm before self-admin5.76.59.9-1.4-2.2-2.7-3.01.7-2.2-2.7-2.0-2.5-3.0-2.72.72.7-2.7-2.5-3.1
Time in closed arm after self-admin1.41.53.10.0-0.9-1.5-1.70.1-0.6-1.3-0.5-1.1-1.7-1.41.41.4-1.4-0.9-1.8
Time in open arm before self-admin3.13.34.61.42.01.32.1-1.51.61.81.72.11.72.0-2.0-2.02.01.71.7
Time in open arm after self-admin1.51.73.70.50.91.51.5-0.71.01.40.81.11.91.3-1.3-1.31.31.21.9
Sum of active levers in priming session hrs 5-60.20.20.5-0.7-0.00.70.50.6-0.30.4-0.30.00.70.3-0.4-0.30.30.10.7
Time to tail flick, vehicle, before self-admin0.00.00.2-0.4-0.10.20.20.4-0.30.1-0.3-0.10.10.1-0.1-0.10.1-0.10.1
Time to tail flick, vehicle, after self-admin0.40.41.9-1.4-0.70.20.11.2-0.9-0.3-1.1-0.60.2-0.30.20.3-0.2-0.60.1
Time to tail flick, test, before self-admin1.11.12.20.50.91.21.2-0.60.81.10.70.91.41.0-1.1-1.01.01.01.5
Time to tail flick, test, after self-admin0.50.50.9-0.4-0.9-0.5-0.90.5-0.5-0.9-0.7-0.8-0.7-0.80.80.8-0.8-0.7-0.6
Delta time to tail flick, vehicle, before/after SA0.30.31.1-1.0-0.6-0.0-0.20.9-0.7-0.4-0.8-0.5-0.1-0.30.30.4-0.3-0.6-0.2
Delta time to tail flick, test, before/after SA1.31.22.50.1-1.0-1.1-1.60.1-0.4-1.2-0.5-1.0-1.3-1.31.31.2-1.3-0.8-1.4
Ambulatory time before self-admin2.72.94.81.41.42.01.5-1.61.91.71.61.52.21.5-1.5-1.51.51.92.1
Ambulatory time after self-admin0.20.20.7-0.0-0.70.0-0.8-0.00.0-0.3-0.3-0.70.1-0.80.80.7-0.7-0.10.0
Total heroin consumption0.91.13.0-0.30.41.71.1-0.10.61.30.30.61.70.9-0.9-0.90.91.01.7
Area under the delay curve0.10.10.20.50.4-0.50.1-0.40.2-0.20.30.3-0.40.1-0.1-0.10.1-0.0-0.4
Delay disc. indifference point, 0s delay0.91.01.4-1.0-1.2-0.7-1.01.1-1.1-1.0-1.1-1.2-0.7-1.11.11.1-1.1-1.0-0.7
Delay disc. indifference point, 16s delay0.50.50.80.90.80.40.7-0.90.80.60.80.70.60.7-0.7-0.70.70.70.6
Delay disc. indifference point, 2s delay0.30.41.81.30.5-0.4-0.1-1.30.9-0.10.80.4-0.40.1-0.1-0.10.10.3-0.4
Delay disc. indifference point, 24s delay0.10.10.50.1-0.1-0.7-0.30.0-0.2-0.5-0.0-0.0-0.6-0.20.20.2-0.2-0.3-0.6
Delay disc. indifference point, 4s delay0.10.10.4-0.30.1-0.70.00.3-0.4-0.4-0.10.0-0.60.00.00.0-0.0-0.4-0.6
Delay disc. indifference point, 8s delay0.30.30.80.70.9-0.10.6-0.60.40.20.70.8-0.10.7-0.6-0.60.60.4-0.1
Delay discount exponential model param0.10.10.4-0.4-0.30.7-0.00.3-0.10.3-0.3-0.30.6-0.10.00.1-0.10.10.6
Delay discount hyperbolic model param0.10.10.6-0.4-0.30.80.00.3-0.10.4-0.3-0.20.7-0.00.00.0-0.00.20.7
Fecal boli incidents, locomotor time 10.60.72.1-1.4-0.9-0.1-0.31.5-1.2-0.4-1.2-0.9-0.1-0.60.60.6-0.6-0.9-0.1
Change in fecal boli incidents, locomotor task0.90.82.5-0.4-0.3-1.4-0.70.5-0.8-1.3-0.4-0.4-1.6-0.60.60.6-0.6-1.0-1.6
Time >=10cm from walls, locomotor time 10.30.30.70.2-0.5-0.5-0.8-0.1-0.1-0.7-0.1-0.5-0.7-0.70.70.6-0.6-0.3-0.7
Bouts of movement, locomotor time 11.21.42.0-1.0-0.9-1.4-1.11.2-1.3-1.1-1.1-1.0-1.4-1.11.11.1-1.1-1.3-1.4
Total resting periods, locomotor time 10.80.91.9-0.7-0.6-1.3-0.90.9-1.1-0.9-0.8-0.7-1.4-0.80.80.9-0.9-1.0-1.4
Rest time, locomotor task time 10.70.81.6-0.3-0.5-1.2-1.00.5-0.7-0.8-0.6-0.7-1.3-0.90.90.9-0.9-0.9-1.3
Distance moved, locomotor task time 11.21.42.20.50.91.41.3-0.81.11.10.91.11.51.2-1.2-1.21.21.21.5
Vertical activity count, locomotor time 10.30.31.2-0.8-0.71.10.10.6-0.20.2-0.6-0.41.0-0.10.00.0-0.00.11.0
Time >=10cm from walls, locomotor time 20.80.81.61.10.71.00.5-1.31.30.81.10.70.90.6-0.6-0.70.61.10.9
Bouts of movement, locomotor time 20.10.20.60.50.3-0.7-0.2-0.30.0-0.50.30.2-0.7-0.10.10.1-0.1-0.2-0.7
Total resting periods, locomotor time 20.20.20.7-0.0-0.0-0.8-0.30.2-0.4-0.6-0.1-0.1-0.8-0.20.30.3-0.3-0.5-0.8
Rest time, locomotor task time 20.20.30.6-0.7-0.3-0.5-0.10.8-0.7-0.4-0.7-0.4-0.4-0.30.30.4-0.3-0.7-0.4
Distance moved, locomotor task time 22.32.63.51.51.51.61.4-1.81.91.61.81.61.61.5-1.5-1.61.61.91.6
Vertical activity count, locomotor time 20.20.21.1-0.5-0.31.10.20.30.00.3-0.3-0.10.90.2-0.2-0.20.20.30.9
Weight adjusted by age4.04.56.92.52.21.71.9-2.62.52.02.32.21.72.0-2.0-2.12.02.21.7
Seeking ratio, delayed vs. immediate footshock3.33.75.91.72.41.12.1-1.91.91.72.12.41.22.2-2.2-2.22.21.81.2
Locomotion in novel chamber0.70.91.80.70.80.81.1-0.70.91.10.70.81.30.9-0.9-0.90.90.91.3
Locomotion in novel chamber post-restriction0.30.40.7-0.0-0.4-0.8-0.80.2-0.4-0.7-0.3-0.5-0.8-0.70.70.7-0.7-0.5-0.9
Progressive ratio0.00.00.1-0.3-0.40.1-0.3-0.10.1-0.3-0.3-0.20.1-0.20.20.2-0.2-0.20.0
Food seeking constrained by brief footshock2.83.44.6-2.1-1.9-1.4-1.72.0-2.0-1.7-2.0-2.0-1.6-1.81.81.8-1.8-1.9-1.6
Seeking ratio, punishment vs. effort1.01.31.8-1.0-1.1-1.0-1.11.3-1.3-0.9-1.1-1.2-1.1-1.11.11.1-1.1-1.1-1.1
Run reversals in cocaine runway, females3.23.25.81.11.22.41.8-1.41.82.01.41.42.31.6-1.7-1.71.71.92.3
Run reversals in cocaine runway, males0.10.10.30.50.20.1-0.1-0.50.30.00.40.2-0.40.1-0.1-0.10.10.3-0.3
Latency to leave start box in cocaine runway1.11.33.00.40.71.71.2-0.20.61.30.60.81.71.1-1.1-1.11.11.11.7
Latency to leave start box in cocaine runway, F1.92.13.51.41.11.91.2-1.21.51.71.41.11.81.2-1.2-1.31.31.71.8
Latency to leave start box in cocaine runway, M1.31.35.4-2.3-1.00.10.12.3-1.8-0.3-1.6-0.90.4-0.40.30.5-0.4-1.00.3
Cd content in liver0.20.20.6-0.50.8-0.10.80.4-0.40.20.20.7-0.10.7-0.7-0.60.60.1-0.1
Co content in liver0.20.20.50.70.7-0.7-0.1-0.60.3-0.10.60.5-0.60.1-0.1-0.10.10.1-0.6
Cu content in liver0.10.10.20.30.40.10.2-0.50.4-0.00.40.40.10.3-0.3-0.30.30.30.1
Fe content in liver0.50.51.50.6-0.6-0.6-1.2-0.50.2-0.70.1-0.6-0.7-1.01.00.9-1.0-0.2-0.7
K content in liver0.40.40.80.80.50.60.3-0.90.90.50.70.50.60.4-0.4-0.40.40.70.6
Mg content in liver0.90.91.61.21.00.80.9-1.31.20.61.11.00.80.9-0.9-0.90.91.00.8
Mn content in liver2.12.42.71.31.41.71.6-1.41.61.61.41.51.61.6-1.6-1.61.61.61.6
Na content in liver0.20.20.40.50.00.7-0.2-0.60.60.40.40.10.6-0.10.1-0.0-0.00.50.6
Rb content in liver0.81.01.7-0.1-0.9-1.2-1.30.2-0.5-1.2-0.6-1.1-1.2-1.21.21.2-1.2-0.9-1.2
Se content in liver1.61.93.5-0.6-1.6-1.2-1.90.7-0.9-1.3-1.1-1.5-1.2-1.81.81.7-1.8-1.1-1.2
Sr content in liver0.00.00.1-0.20.10.40.10.1-0.00.20.1-0.00.30.1-0.1-0.10.10.20.3
Zn content in liver3.23.55.01.32.01.72.2-1.41.61.81.72.01.82.2-2.2-2.12.21.81.8