Hub : Genes

Brf1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000014595 0.14 0.09 5.6e-17 0.12 0.13 0.12 0.13 4.4e-13 2.8e-14 1.3e-13 6.4e-14
2 Adipose intron excision ratio chr6:132061560:132064872 0.09 0.06 1.2e-07 0.04 0.05 0.05 0.04 7.9e-05 3.0e-06 5.1e-06 1.2e-05
3 BLA gene expression ENSRNOG00000014595 0.19 0.09 1.7e-12 0.2 0.22 0.21 0.22 5.3e-11 6.5e-12 1.5e-11 6.9e-12
4 BLA mRNA stability ENSRNOG00000014595 0.19 0.09 1.1e-12 0.2 0.21 0.2 0.19 3.5e-11 1.6e-11 8.4e-11 1.2e-10
5 Brain gene expression ENSRNOG00000014595 0.28 0.14 0.0e+00 0.19 0.01 0.2 0.03 3.4e-17 4.6e-02 3.6e-18 6.7e-04
6 Brain intron excision ratio chr6:132044828:132046119 0.03 0.03 9.7e-03 0 -0 0 0 1.5e-01 6.2e-01 1.6e-01 2.2e-01
7 Brain intron excision ratio chr6:132044831:132046119 0.03 0.03 7.8e-03 0 -0 0 0 1.2e-01 5.1e-01 1.0e-01 1.4e-01
8 Brain mRNA stability ENSRNOG00000014595 0.31 0.14 0.0e+00 0.25 0.01 0.26 0.01 7.4e-23 2.9e-02 2.3e-24 3.8e-02
9 IL gene expression ENSRNOG00000014595 0.2 0.12 3.6e-05 0.2 0.14 0.12 0.2 1.6e-05 3.7e-04 9.4e-04 1.8e-05
10 IL mRNA stability ENSRNOG00000014595 0.16 0.11 5.0e-04 0.12 0.08 0.07 0.11 1.0e-03 6.7e-03 1.1e-02 1.6e-03
11 Liver gene expression ENSRNOG00000014595 0.16 0.09 0.0e+00 0.16 0.17 0.15 0.16 1.1e-17 4.2e-18 2.3e-16 1.1e-17
12 Liver intron excision ratio chr6:132046382:132050296 0.06 0.04 7.2e-08 0.06 0.06 0.05 0.05 8.4e-07 8.2e-07 1.5e-06 1.5e-06
13 Liver intron excision ratio chr6:132046408:132050296 0.06 0.04 5.6e-08 0.05 0.06 0.05 0.05 1.1e-06 7.0e-07 1.5e-06 1.1e-06
14 Liver intron excision ratio chr6:132061560:132064872 0.05 0.04 2.8e-07 0.04 0.05 0.04 0.04 1.8e-05 4.9e-06 1.7e-05 1.3e-05
15 Liver intron excision ratio chr6:132061560:132068713 0.09 0.06 1.1e-10 0.08 0.09 0.08 0.08 3.1e-09 1.0e-09 5.3e-09 3.3e-09
16 Liver mRNA stability ENSRNOG00000014595 0.04 0.04 6.3e-04 0.03 0.02 0.03 0.03 4.6e-04 1.4e-03 4.7e-04 6.9e-04
17 NAcc gene expression ENSRNOG00000014595 0.03 0.03 4.5e-03 0.03 0.03 0.02 0.02 5.8e-03 4.5e-03 6.5e-03 9.0e-03
18 NAcc mRNA stability ENSRNOG00000014595 0.14 0.11 2.0e-05 0.06 0.07 0.06 0.06 3.4e-05 4.3e-06 6.3e-05 1.9e-05
19 OFC gene expression ENSRNOG00000014595 0.25 0.14 1.5e-05 0.08 0.11 0.1 0.09 4.9e-03 1.4e-03 2.9e-03 4.8e-03
20 OFC mRNA stability ENSRNOG00000014595 0.37 0.21 1.0e-05 0.14 0.19 0.09 0.14 3.8e-04 3.0e-05 3.4e-03 4.0e-04
21 PL gene expression ENSRNOG00000014595 0.22 0.1 0.0e+00 0.24 0.3 0.28 0.28 1.3e-18 9.9e-23 2.9e-21 2.1e-21
22 PL mRNA stability ENSRNOG00000014595 0.24 0.11 0.0e+00 0.32 0.32 0.33 0.33 6.3e-25 5.9e-25 1.9e-25 1.1e-25

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
BMI with tail1.85.89.4-2.42.72.42.42.52.7-3.12.82.32.4-2.42.2-2.12.4-2.6-2.72.12.21.91.52.22.4
BMI without tail0.81.73.2-1.31.21.21.31.80.4-1.31.71.41.5-1.21.2-1.21.3-1.3-0.81.31.51.11.51.21.4
Body weight1.46.19.22.6-2.3-2.5-2.6-2.3-1.52.0-1.9-2.6-2.52.6-2.82.8-2.62.31.5-2.8-2.4-3.0-2.6-2.8-2.5
Epididymis fat weight2.04.88.4-2.32.52.32.22.12.6-2.42.32.12.3-2.22.0-2.02.2-2.3-2.91.91.61.91.02.12.1
Glucose0.10.10.80.1-0.3-0.2-0.10.0-0.90.5-0.30.00.00.10.1-0.1-0.10.30.80.20.10.20.60.0-0.0
Heart weight0.10.20.5-0.40.20.40.40.40.2-0.10.00.40.4-0.40.5-0.50.4-0.2-0.10.60.30.70.60.50.5
Left kidney weight2.98.29.02.9-2.9-3.0-3.0-3.0-2.12.8-2.9-2.9-2.83.0-3.03.0-3.02.92.3-3.0-2.9-2.9-2.7-3.0-2.8
Right kidney weight1.44.04.42.1-2.1-2.1-2.1-2.0-1.72.1-2.1-2.0-2.02.1-2.12.1-2.12.11.9-2.0-1.9-2.0-1.7-2.0-1.8
Tail length5.115.518.64.1-4.1-4.1-4.1-3.7-4.04.3-3.9-3.9-3.84.1-4.04.0-4.14.13.7-3.9-3.6-3.9-3.1-4.0-4.0
Length with tail9.434.337.26.1-5.9-6.0-6.0-5.9-4.85.9-5.7-6.0-5.96.1-6.16.1-6.15.94.8-6.1-5.7-6.1-5.3-6.1-6.0
Length without tail5.912.815.33.6-3.4-3.6-3.7-3.9-1.93.3-3.5-3.8-3.83.6-3.83.8-3.73.52.3-3.9-3.7-3.9-3.8-3.8-3.7
Liver weight, left2.64.24.72.1-2.0-2.1-2.1-1.9-1.82.0-1.9-2.0-2.12.1-2.22.2-2.12.11.7-2.1-2.0-2.2-1.9-2.1-2.1
Liver weight, right0.50.92.10.9-0.6-0.8-0.9-1.00.40.2-0.5-1.1-1.10.9-1.11.2-1.00.6-0.1-1.3-0.9-1.4-1.4-1.2-1.1
Parametrial fat weight0.10.20.4-0.40.50.40.50.50.3-0.60.50.40.4-0.50.4-0.40.4-0.5-0.40.40.50.40.50.40.5
Retroperitoneal fat weight0.10.20.9-0.40.50.50.40.41.0-0.50.50.40.3-0.40.3-0.30.4-0.5-0.90.20.20.2-0.10.30.2
Intraocular pressure0.30.41.1-0.60.50.60.60.70.3-0.40.60.70.8-0.60.7-0.70.6-0.6-0.10.80.90.71.00.70.6
Extensor digitorum longus weight9.839.244.26.4-6.4-6.3-6.4-6.6-5.06.6-6.6-6.4-6.66.4-6.36.3-6.46.55.2-6.3-6.4-6.1-5.7-6.3-6.4
Soleus weight2.36.611.92.4-2.1-2.3-2.5-3.2-0.42.1-2.8-2.9-2.92.4-2.72.7-2.52.30.6-2.8-3.1-2.7-3.5-2.6-2.8
Tibialis anterior weight1.03.45.41.8-1.7-1.7-1.8-2.3-0.81.7-2.2-2.2-2.21.7-1.81.8-1.81.81.0-1.9-2.0-1.8-2.0-1.9-2.0
Tibia length0.10.20.30.5-0.5-0.6-0.5-0.3-0.50.6-0.3-0.4-0.20.5-0.50.5-0.50.50.6-0.5-0.5-0.5-0.4-0.5-0.4
Number of licking bursts1.11.32.5-1.11.01.11.11.20.3-1.01.11.21.2-1.11.2-1.31.1-1.1-0.31.31.41.21.61.21.2
Food consumed during 24 hour testing period0.91.11.41.1-1.0-1.1-1.1-1.1-0.90.9-1.0-1.1-1.11.1-1.11.1-1.11.00.9-1.1-0.9-1.2-0.9-1.1-1.1
Times rat made contact with spout0.20.20.60.5-0.3-0.4-0.4-0.5-0.10.0-0.3-0.6-0.60.4-0.50.6-0.50.30.1-0.6-0.3-0.8-0.5-0.6-0.5
Mean time between licks in bursts0.60.81.2-0.90.90.90.91.10.6-0.91.11.01.1-0.90.9-0.90.9-0.9-0.60.91.00.80.90.90.9
Mean num. licks in bursts1.51.83.11.3-1.1-1.2-1.3-1.4-0.41.0-1.3-1.5-1.51.3-1.51.5-1.31.20.4-1.6-1.5-1.6-1.8-1.4-1.4
Std. dev. time between licks in bursts0.10.10.30.3-0.3-0.3-0.3-0.4-0.20.3-0.5-0.4-0.40.3-0.20.2-0.30.30.2-0.3-0.3-0.2-0.3-0.3-0.3
Water consumed over 24 hours1.31.53.41.3-1.4-1.3-1.2-1.0-1.81.2-1.0-1.1-1.11.3-1.11.1-1.21.21.8-1.1-0.6-1.2-0.3-1.2-1.1
Indifference point 0 sec6.510.412.53.4-3.2-3.3-3.3-3.3-2.52.9-3.1-3.4-3.43.3-3.43.4-3.43.12.6-3.5-3.1-3.5-3.0-3.5-3.3
Indifference point AUC6.77.912.12.8-2.4-2.7-2.8-3.0-1.02.1-2.5-3.0-3.12.8-3.13.1-2.92.51.2-3.3-3.0-3.4-3.5-3.1-3.1
Indifference point function ln k0.40.63.10.7-0.9-0.8-0.7-0.4-1.81.1-0.7-0.5-0.40.7-0.50.5-0.70.81.5-0.4-0.3-0.40.2-0.5-0.5
Indifference point function log k0.40.63.10.7-0.9-0.8-0.7-0.4-1.81.1-0.7-0.5-0.40.7-0.50.5-0.70.81.5-0.4-0.3-0.40.2-0.5-0.5
Delay discounting total patch changes 0 sec7.812.615.23.7-3.5-3.6-3.6-3.7-2.73.2-3.4-3.7-3.73.6-3.83.8-3.73.52.7-3.8-3.4-3.9-3.4-3.9-3.6
Delay discounting total patch changes 12 sec3.64.76.62.4-2.1-2.3-2.2-2.2-1.61.8-1.9-2.4-2.42.2-2.32.3-2.32.01.9-2.4-1.7-2.6-1.7-2.5-2.4
Delay discounting total patch changes 18 sec2.63.54.81.9-1.7-1.8-1.9-2.0-1.01.4-1.7-2.0-2.11.9-2.02.0-1.91.71.3-2.1-1.7-2.2-1.9-2.1-2.1
Delay discounting total patch changes 24 sec1.31.72.61.3-1.1-1.3-1.3-1.3-0.40.9-1.1-1.3-1.41.3-1.51.5-1.31.10.6-1.5-1.3-1.6-1.6-1.5-1.4
Delay discounting total patch changes 6 sec6.39.714.23.1-2.7-3.0-3.1-3.4-1.22.3-2.8-3.3-3.43.1-3.53.5-3.22.81.4-3.6-3.2-3.8-3.8-3.5-3.3
Delay discounting time to switch 0 sec12.118.520.9-4.54.34.54.44.33.7-4.24.14.64.3-4.44.5-4.54.5-4.3-3.74.54.04.63.84.54.3
Delay discounting water rate 0 sec17.427.730.65.5-5.4-5.5-5.4-5.3-5.05.2-5.2-5.5-5.35.4-5.45.4-5.55.35.0-5.3-4.7-5.4-4.1-5.5-5.2
Delay discounting water rate 12 sec5.38.016.13.1-3.1-3.1-2.9-2.1-4.02.8-2.2-2.5-2.63.0-2.82.8-2.92.84.0-2.6-1.6-3.0-0.9-2.9-2.6
Delay discounting water rate 18 sec3.54.77.32.4-2.3-2.4-2.2-1.8-2.72.1-1.8-2.1-2.02.3-2.22.2-2.32.22.6-2.1-1.5-2.3-1.0-2.3-2.0
Delay discounting water rate 24 sec2.73.76.52.1-2.0-2.1-2.0-1.6-2.51.6-1.5-2.0-1.92.1-1.92.0-2.01.82.6-1.9-1.0-2.2-0.7-2.1-1.6
Delay discounting water rate 6 sec4.26.16.92.6-2.6-2.6-2.5-2.4-2.62.5-2.4-2.5-2.42.6-2.52.5-2.62.52.6-2.4-2.0-2.5-1.6-2.5-2.3
Locomotor activity0.10.10.20.4-0.4-0.4-0.4-0.3-0.40.3-0.2-0.4-0.20.4-0.40.4-0.40.40.5-0.4-0.2-0.4-0.2-0.4-0.4
Locomotor testing distance0.10.10.40.3-0.4-0.3-0.3-0.2-0.50.4-0.2-0.3-0.20.3-0.30.3-0.30.30.6-0.2-0.1-0.30.0-0.3-0.3
Locomotor testing rearing2.13.35.3-1.82.01.91.91.62.2-2.32.01.51.6-1.91.7-1.71.8-2.0-1.91.61.81.51.41.71.6
Light reinforcement 10.00.00.00.1-0.1-0.1-0.1-0.0-0.20.0-0.0-0.1-0.10.1-0.10.1-0.10.10.2-0.10.0-0.10.1-0.1-0.0
Light reinforcement 21.31.73.1-1.41.41.41.31.31.7-1.31.41.41.4-1.31.2-1.21.3-1.3-1.71.20.81.20.51.41.2
Reaction time number correct4.36.17.12.5-2.5-2.5-2.5-2.6-2.22.7-2.6-2.5-2.52.5-2.52.5-2.52.52.2-2.5-2.4-2.4-2.2-2.5-2.6
Reaction time mean minus median0.00.10.2-0.20.20.20.20.3-0.0-0.20.40.30.3-0.20.2-0.20.2-0.2-0.10.20.40.10.30.20.1
Reaction time mean minus median AUC0.00.00.1-0.10.10.10.10.2-0.20.00.20.20.2-0.10.2-0.20.1-0.10.10.20.30.20.40.2-0.1
Reaction time num false alarms1.82.52.81.6-1.6-1.6-1.7-1.6-1.31.7-1.5-1.6-1.61.6-1.61.6-1.61.61.4-1.6-1.6-1.6-1.5-1.6-1.6
Reaction time num false alarms AUC2.02.83.41.7-1.8-1.8-1.8-1.6-1.61.9-1.6-1.6-1.61.8-1.71.7-1.71.81.6-1.7-1.7-1.6-1.5-1.7-1.7
Reaction time trials correct on left4.36.17.12.5-2.5-2.5-2.5-2.6-2.22.7-2.6-2.5-2.52.5-2.52.5-2.52.52.2-2.5-2.4-2.4-2.2-2.5-2.6
Reaction time trials on left4.36.27.22.5-2.6-2.5-2.5-2.5-2.22.7-2.6-2.5-2.52.5-2.52.5-2.52.62.2-2.5-2.4-2.4-2.1-2.5-2.6
Reaction time mean2.12.94.2-1.71.51.61.72.00.6-1.41.92.01.9-1.61.8-1.81.7-1.6-0.71.91.91.82.11.81.7
Reaction time mean AUC1.31.82.9-1.31.21.21.31.60.3-1.01.51.51.5-1.21.4-1.41.3-1.2-0.51.51.51.41.71.41.3
Median of all reaction times1.92.64.3-1.51.31.51.61.90.3-1.21.71.91.8-1.51.7-1.71.6-1.4-0.41.81.81.82.11.71.6
Reaction time omissions1.01.33.41.2-1.3-1.3-1.2-0.7-1.81.4-0.9-0.9-1.01.2-1.01.0-1.21.21.8-0.9-0.6-1.0-0.2-1.1-1.1
Reaction time false alarm rate0.10.10.20.4-0.4-0.4-0.4-0.2-0.40.5-0.2-0.3-0.30.4-0.40.4-0.40.40.5-0.4-0.4-0.4-0.3-0.4-0.3
Reaction time premature initiation rate0.20.20.60.5-0.5-0.5-0.5-0.4-0.80.6-0.5-0.4-0.40.5-0.40.4-0.40.50.7-0.3-0.3-0.3-0.1-0.4-0.5
Reaction time premature initiations2.13.03.81.8-1.8-1.8-1.8-1.8-1.71.9-1.9-1.7-1.71.8-1.71.7-1.81.81.6-1.7-1.7-1.6-1.4-1.7-1.9
Std. dev. reaction times1.31.83.3-1.31.11.21.31.70.2-1.01.51.61.6-1.31.4-1.41.3-1.2-0.41.51.61.51.81.51.3
Reaction time trials completed4.36.27.22.5-2.6-2.5-2.5-2.5-2.22.7-2.6-2.5-2.52.5-2.52.5-2.52.62.2-2.5-2.4-2.4-2.1-2.5-2.6
Reaction time trials AUC4.56.47.32.6-2.6-2.6-2.6-2.6-2.32.7-2.6-2.6-2.62.6-2.52.5-2.62.62.3-2.5-2.5-2.5-2.2-2.6-2.6
Social response proportion0.50.61.7-0.60.40.50.61.0-0.6-0.40.90.91.0-0.50.7-0.70.6-0.50.50.81.00.71.30.70.9
Social responses0.50.61.4-0.70.60.70.80.90.0-0.60.90.91.0-0.70.9-0.90.8-0.7-0.10.91.00.81.20.80.9
Social time0.30.53.00.1-0.5-0.3-0.10.6-1.70.70.20.40.40.20.2-0.2-0.00.31.60.40.60.31.40.20.2
Conditioned locomotion1.72.02.41.5-1.4-1.5-1.5-1.3-1.21.3-1.3-1.4-1.51.5-1.51.5-1.51.41.3-1.5-1.3-1.6-1.2-1.5-1.5
Cocaine response after cond. corrected0.20.21.1-0.10.30.20.1-0.31.0-0.5-0.0-0.2-0.2-0.1-0.10.20.0-0.2-1.1-0.3-0.3-0.3-0.8-0.1-0.1
Cocaine response after cond. not corrected0.50.62.5-0.71.00.80.70.41.5-1.30.80.40.4-0.70.4-0.40.6-0.9-1.60.20.40.1-0.30.40.4
Cocaine response before conditioning2.63.14.9-1.71.81.71.72.21.2-1.92.22.02.0-1.71.7-1.71.7-1.8-1.21.71.91.51.71.71.8
Saline control response0.10.10.20.3-0.2-0.2-0.2-0.4-0.20.1-0.4-0.5-0.50.2-0.20.2-0.20.20.2-0.2-0.1-0.2-0.1-0.3-0.3
Condit. Reinf. active minus inactive responses0.40.51.40.8-0.7-0.8-0.7-0.4-1.10.5-0.3-0.6-0.50.7-0.60.6-0.70.61.2-0.6-0.1-0.80.1-0.8-0.6
Condit. Reinf. active-inactive response ratio0.20.21.00.4-0.5-0.5-0.4-0.1-1.00.4-0.2-0.2-0.20.4-0.30.3-0.40.41.0-0.20.0-0.30.3-0.3-0.2
Condit. Reinf. active responses0.10.10.40.1-0.0-0.10.00.4-0.6-0.20.50.20.20.10.00.0-0.0-0.10.60.00.5-0.20.6-0.10.1
Condit. Reinf. inactive responses0.30.41.0-0.50.70.60.60.80.5-0.81.00.70.6-0.60.5-0.50.6-0.7-0.40.50.90.30.70.50.5
Condit. Reinf. lever presses2.02.74.1-1.61.51.61.71.80.8-1.61.71.71.7-1.61.7-1.71.7-1.7-0.81.72.01.62.01.71.7
Condit. Reinf. lever reinforcers received0.10.10.50.1-0.1-0.1-0.00.4-0.7-0.10.40.10.10.1-0.00.0-0.1-0.10.70.00.6-0.20.7-0.10.0
Pavlov. Cond. lever latency3.24.46.22.0-2.0-2.0-2.1-2.3-1.12.1-2.3-2.2-2.32.0-2.12.1-2.12.11.0-2.2-2.5-2.0-2.5-2.1-2.2
Pavlov. Cond. magazine entry latency3.84.36.9-2.02.22.12.22.11.8-2.62.31.91.9-2.12.0-2.02.1-2.3-1.71.92.41.72.01.92.1
Pavlov. Cond. change in total contacts6.08.49.3-2.92.92.93.02.92.2-3.02.82.93.0-3.03.0-3.03.0-2.9-2.23.03.03.02.93.03.0
Pavlov. Cond. index score4.86.28.2-2.42.52.52.62.61.8-2.82.72.42.5-2.52.5-2.52.5-2.6-1.82.52.92.32.62.42.5
Pavlov. Cond. latency score4.35.47.9-2.32.42.32.42.41.9-2.82.62.22.3-2.42.3-2.32.3-2.5-1.92.22.62.02.32.22.3
Pavlov. Cond. lever contacts3.44.86.6-2.12.22.12.22.41.4-2.42.42.22.3-2.22.2-2.22.2-2.3-1.42.22.62.02.42.12.2
Pavlov. Cond. magazine entry number3.34.06.31.9-2.1-2.0-2.1-2.0-1.62.5-2.1-1.8-1.82.1-2.02.0-2.02.21.5-1.9-2.4-1.7-2.1-1.9-2.0
Pavlov. Cond. intertrial magazine entries4.55.97.22.5-2.6-2.6-2.5-2.1-2.62.7-2.1-2.2-2.22.6-2.52.5-2.52.52.6-2.4-2.1-2.5-1.7-2.5-2.5
Pavlov. Cond. lever-magazine prob. diff.5.57.19.3-2.62.72.72.82.72.1-3.12.82.62.7-2.72.7-2.72.7-2.8-2.02.63.02.42.72.62.7
Pavlov. Cond. response bias3.64.97.1-2.12.22.22.32.41.4-2.52.52.22.3-2.22.2-2.22.2-2.3-1.42.22.72.02.52.12.3
Conditioned reinforcement - actives1.01.02.31.1-1.1-1.1-1.0-0.8-1.51.2-0.9-0.9-0.91.0-0.90.9-1.01.01.4-0.9-0.6-0.9-0.3-1.0-1.0
Conditioned reinforcement - inactives0.40.40.80.7-0.6-0.7-0.6-0.5-0.90.4-0.3-0.6-0.60.7-0.60.7-0.70.50.8-0.7-0.2-0.8-0.1-0.8-0.8
Conditioned locomotion0.00.00.2-0.10.20.20.10.00.5-0.30.10.00.1-0.10.0-0.00.1-0.2-0.5-0.0-0.0-0.0-0.20.1-0.0
Intermittent access intake day 1-15 change1.51.51.7-1.31.31.31.31.21.1-1.31.21.21.2-1.31.2-1.21.3-1.3-1.31.21.21.10.91.21.1
Intermittent access intake escalation1.41.41.7-1.21.31.31.21.21.0-1.21.11.21.2-1.31.2-1.21.2-1.3-1.31.21.11.20.91.21.1
Intermittent access intake escalation 20.20.20.5-0.40.40.50.40.20.7-0.20.10.40.3-0.40.4-0.40.4-0.3-0.70.40.10.5-0.00.40.3
Intermitt. access day 1 inactive lever presses2.83.14.01.9-1.8-1.8-1.8-1.8-1.71.7-1.5-1.8-1.81.8-1.81.8-1.81.71.8-1.8-1.3-2.0-1.1-1.9-2.0
Intermitt. access day 15 inactive lever presses0.50.51.40.8-0.8-0.8-0.7-0.5-1.20.8-0.5-0.6-0.70.7-0.60.6-0.70.71.1-0.6-0.2-0.70.0-0.7-0.8
Intermitt. access escalation Index0.00.00.30.2-0.2-0.1-0.1-0.0-0.60.0-0.0-0.0-0.10.1-0.00.0-0.10.10.5-0.00.2-0.10.4-0.10.1
Intermittent access day 1 total infusions0.10.10.40.2-0.1-0.2-0.2-0.40.5-0.1-0.1-0.3-0.30.2-0.30.3-0.20.1-0.3-0.4-0.4-0.4-0.6-0.3-0.2
Intermittent access day 15 total infusions0.91.01.6-1.01.11.11.01.01.2-1.21.01.01.0-1.11.0-1.01.0-1.1-1.30.90.90.90.61.01.0
Intermittent access terminal intake (last 3 days)1.31.42.0-1.21.31.31.21.21.4-1.41.21.21.1-1.21.1-1.11.2-1.3-1.41.11.11.00.81.11.1
Intermittent access total infusions0.10.10.4-0.30.40.30.30.20.7-0.50.30.20.3-0.30.2-0.20.3-0.4-0.60.20.20.2-0.00.20.2
Intermittent access day 1 locomotion0.10.10.4-0.20.20.20.1-0.00.6-0.40.1-0.00.1-0.20.0-0.00.1-0.2-0.50.0-0.10.0-0.30.10.2
Intermittent access day 15 total locomotion0.00.00.1-0.20.20.20.20.30.2-0.30.30.10.2-0.20.2-0.20.2-0.2-0.20.20.30.10.20.20.2
Intermittent access total locomotion0.00.10.30.1-0.0-0.1-0.1-0.20.4-0.2-0.0-0.3-0.20.1-0.20.2-0.20.1-0.3-0.3-0.3-0.3-0.5-0.2-0.2
Intermittent access standard deviation0.80.93.6-0.91.21.00.90.61.8-1.51.00.60.6-0.90.6-0.50.8-1.1-1.90.40.50.3-0.20.60.6
Cocaine induced anxiety0.50.51.50.8-0.9-0.8-0.7-0.6-1.00.9-0.8-0.7-0.70.7-0.60.6-0.70.81.2-0.5-0.4-0.5-0.1-0.6-0.6
Post-drug Anxiety0.40.40.80.7-0.7-0.7-0.7-0.6-0.80.6-0.7-0.7-0.70.7-0.60.6-0.70.70.9-0.6-0.5-0.5-0.3-0.6-0.5
Baseline Anxiety0.70.71.5-0.91.00.90.90.71.1-1.10.90.70.7-0.90.8-0.80.9-1.0-1.20.70.70.70.40.80.8
Lifetime Intake0.10.10.2-0.40.40.40.40.40.3-0.40.40.40.4-0.40.4-0.40.4-0.4-0.30.40.40.30.40.40.4
Incentive Sensitization - Responses0.20.20.5-0.30.30.30.40.5-0.0-0.40.50.40.4-0.30.4-0.40.3-0.40.10.40.60.30.70.30.5
Incentive Sensitization - Breakpoint0.10.10.5-0.20.20.20.30.5-0.2-0.30.40.40.4-0.30.3-0.30.3-0.30.20.40.60.30.70.30.4
Progressive ratio test 1 active lever presses0.10.10.4-0.20.20.20.30.4-0.1-0.20.50.30.4-0.20.3-0.30.3-0.30.10.30.60.20.60.20.2
Progressive ratio test 1 breakpoint0.20.20.4-0.30.30.30.40.50.1-0.40.60.40.4-0.40.4-0.40.4-0.4-0.00.40.60.30.60.30.2
Progressive ratio test 1 inactive lever presses2.12.33.81.6-1.7-1.6-1.5-1.4-1.91.7-1.3-1.4-1.41.6-1.51.5-1.61.51.9-1.4-1.0-1.5-0.7-1.5-1.6
Progressive ratio test 2 active lever presses0.00.10.2-0.10.20.10.20.3-0.1-0.30.30.20.3-0.20.2-0.20.2-0.20.10.20.40.10.40.20.2
Progressive ratio test 2 breakpoint0.00.00.1-0.00.00.00.10.2-0.2-0.10.20.10.2-0.00.1-0.10.0-0.10.20.10.30.00.30.00.1
Progressive ratio test 2 inactive lever presses0.10.21.50.2-0.2-0.2-0.10.3-1.20.20.20.10.10.10.0-0.0-0.10.10.90.10.5-0.10.8-0.1-0.1
Total sessions with >9 infusions0.10.10.2-0.20.20.10.20.4-0.2-0.20.40.30.3-0.20.2-0.20.2-0.20.00.20.30.10.30.20.3
Short access day 1 total inactive lever presses0.10.10.3-0.10.10.10.20.4-0.3-0.20.50.20.3-0.10.2-0.20.2-0.20.30.20.60.00.60.10.2
Short access day 10 total inactive lever presses0.20.21.20.5-0.5-0.5-0.4-0.1-0.90.5-0.1-0.3-0.30.5-0.40.4-0.40.41.1-0.30.2-0.50.4-0.5-0.5
Short access day 1 total infusions0.10.10.40.0-0.1-0.1-0.00.2-0.50.10.20.20.20.00.1-0.10.00.10.60.10.30.10.50.00.1
Short access day 10 total infusions0.30.30.5-0.50.50.50.50.60.3-0.60.70.60.6-0.50.5-0.50.5-0.6-0.40.50.60.50.60.50.6
Short access total infusions0.70.81.4-0.80.70.80.91.10.2-0.81.01.01.0-0.81.0-1.00.9-0.8-0.21.01.10.91.20.91.1
Short access day 1 locomotion0.40.50.7-0.70.70.70.70.70.6-0.70.80.70.7-0.70.7-0.70.7-0.7-0.50.70.80.60.70.60.6
Short access day 10 total locomotion0.10.10.5-0.10.30.10.1-0.00.7-0.50.3-0.10.0-0.1-0.10.10.1-0.2-0.6-0.1-0.0-0.2-0.4-0.1-0.1
Short access total locomotion0.10.10.3-0.10.20.10.20.30.0-0.40.50.10.2-0.10.1-0.10.1-0.3-0.00.10.4-0.00.30.10.2
Compulsive drug intake0.70.71.70.7-0.6-0.7-0.8-1.00.30.4-0.7-0.9-0.80.8-0.90.9-0.80.7-0.0-1.0-1.1-1.0-1.3-0.9-0.7
One hour access (0.3 mA shock)0.50.60.90.8-0.6-0.7-0.7-0.8-0.30.5-0.7-0.9-0.90.7-0.80.8-0.80.70.3-0.9-0.7-0.9-0.9-0.9-0.9
One hour access (shock baseline)0.10.10.2-0.30.30.30.40.4-0.0-0.20.30.30.3-0.40.4-0.40.3-0.3-0.10.40.40.40.50.40.1
Number of responses in last shaping day0.70.70.8-0.80.80.80.80.70.6-0.70.80.90.8-0.90.9-0.90.9-0.8-0.50.90.90.90.90.90.9
Context. condit. distance diff. score3.44.25.42.1-2.2-2.1-2.1-2.2-1.92.3-2.3-2.1-1.92.1-2.02.0-2.12.22.0-1.9-2.0-1.9-1.6-2.0-2.0
Locomotion velocity, session 10.10.20.50.5-0.3-0.4-0.3-0.3-0.2-0.1-0.1-0.5-0.40.4-0.50.5-0.40.20.2-0.5-0.0-0.7-0.2-0.6-0.5
Locomotion distance, session 10.20.31.1-0.50.70.60.60.31.0-1.00.60.30.3-0.60.4-0.40.5-0.7-1.00.20.50.10.10.30.3
Locomotion velocity, session 20.40.51.4-0.50.60.60.70.80.1-1.01.00.60.6-0.60.6-0.60.6-0.8-0.10.61.20.31.10.40.6
Locomotion distance, session 20.70.91.6-0.90.90.91.01.00.5-1.21.10.90.9-0.91.0-1.00.9-1.0-0.51.01.30.81.20.91.1
Locomotion velocity, session 30.00.10.3-0.10.20.20.2-0.20.4-0.5-0.1-0.2-0.2-0.30.2-0.20.2-0.3-0.30.10.30.00.10.00.0
Locomotion distance, session 30.10.10.4-0.10.20.20.30.1-0.0-0.50.20.00.0-0.20.3-0.30.2-0.30.10.20.60.10.60.10.2
Stereotopy head waving bouts, day 30.10.10.20.3-0.3-0.2-0.2-0.3-0.30.2-0.4-0.3-0.40.2-0.20.2-0.20.30.3-0.2-0.2-0.2-0.2-0.3-0.2
Stereotopy head waving duration, day 30.10.10.30.3-0.4-0.3-0.3-0.3-0.50.4-0.4-0.3-0.40.3-0.20.2-0.30.30.5-0.2-0.3-0.1-0.1-0.2-0.2
Locomotion velocity, session 70.10.20.90.1-0.1-0.1-0.2-0.40.70.2-0.4-0.2-0.10.1-0.30.3-0.20.2-0.7-0.3-0.8-0.1-1.0-0.2-0.3
Locomotion distance, session 70.81.01.1-1.01.01.11.01.01.0-1.01.01.11.0-1.11.0-1.01.0-1.0-1.01.00.91.00.81.01.0
Stereotopy head waving bouts, day 72.73.14.01.8-1.8-1.8-1.8-1.9-1.41.9-2.0-1.8-1.91.7-1.71.7-1.81.81.4-1.7-1.9-1.6-1.7-1.7-1.8
Stereotopy head waving duration, day 71.82.13.11.4-1.4-1.4-1.5-1.7-0.81.5-1.7-1.6-1.61.4-1.51.5-1.41.50.7-1.5-1.8-1.3-1.7-1.4-1.6
Locomotion velocity, session 82.32.83.31.7-1.6-1.7-1.7-1.8-1.11.6-1.7-1.8-1.71.7-1.81.8-1.71.71.1-1.8-1.8-1.7-1.8-1.7-1.7
Locomotion distance, session 80.40.61.20.8-0.8-0.8-0.8-1.1-0.50.7-1.0-1.0-0.90.8-0.80.8-0.80.80.6-0.8-0.8-0.8-0.7-0.8-0.8
Degree of sensitization distance0.20.20.5-0.50.40.50.40.50.6-0.20.40.70.7-0.40.4-0.40.5-0.4-0.60.50.10.60.10.60.5
Degree of sensitization stereotypy1.11.21.71.1-1.1-1.1-1.1-1.2-0.61.2-1.2-1.1-1.21.1-1.11.1-1.11.10.6-1.1-1.3-1.0-1.3-1.1-1.2
Condit. Reinf. active minus inactive responses0.30.30.9-0.50.60.60.60.41.0-0.70.50.40.5-0.60.5-0.50.5-0.6-0.80.40.50.40.20.40.4
Condit. Reinf. active-inactive response ratio1.71.93.7-1.41.51.41.41.21.9-1.51.41.31.4-1.41.2-1.21.4-1.4-1.81.21.01.20.61.31.2
Condit. Reinf. active responses0.10.10.30.2-0.0-0.2-0.2-0.30.5-0.2-0.1-0.4-0.40.2-0.30.4-0.30.0-0.3-0.4-0.2-0.5-0.5-0.4-0.4
Condit. Reinf. inactive responses2.22.63.61.7-1.6-1.6-1.6-1.7-1.41.3-1.6-1.9-1.91.6-1.71.7-1.71.51.4-1.7-1.3-1.8-1.3-1.8-1.7
Incentive salience index mean0.10.10.8-0.00.20.10.0-0.20.9-0.40.1-0.2-0.2-0.0-0.20.2-0.0-0.2-0.8-0.3-0.2-0.4-0.6-0.2-0.2
Condit. Reinf. lever presses0.30.31.30.4-0.2-0.4-0.5-0.60.50.1-0.3-0.6-0.60.5-0.70.7-0.50.3-0.4-0.8-0.7-0.8-1.1-0.6-0.6
Time in familiar zone, hab. session 10.00.00.2-0.10.00.10.1-0.30.20.1-0.4-0.1-0.1-0.10.1-0.10.10.0-0.30.1-0.20.2-0.20.1-0.1
Time in novel zone, hab. session 10.90.91.8-0.80.90.80.91.20.3-1.11.21.01.1-0.90.9-0.90.9-1.0-0.30.91.30.71.30.81.1
Total zone transitions, hab. session 10.60.81.4-0.90.70.80.91.00.2-0.60.81.01.0-0.81.0-1.00.9-0.8-0.11.01.01.11.21.01.1
Total locomotion distance, hab. session 10.10.21.20.1-0.4-0.2-0.10.2-1.10.5-0.10.10.20.20.1-0.1-0.10.31.10.20.20.20.70.10.2
Locomotion velocity, hab. session 10.40.51.80.7-0.9-0.8-0.7-0.4-1.31.1-0.7-0.5-0.50.7-0.60.5-0.70.81.4-0.4-0.5-0.4-0.0-0.6-0.5
Time in familiar zone, hab. session 20.60.62.20.6-0.4-0.5-0.6-1.00.50.3-0.8-0.9-0.80.6-0.80.8-0.70.5-0.5-0.9-1.1-0.8-1.5-0.7-0.7
Time in novel zone, hab. session 21.11.12.5-0.90.80.91.01.30.1-0.81.11.11.1-1.01.1-1.11.0-0.9-0.11.21.41.11.61.01.1
Total zone transitions, hab. session 20.20.20.8-0.40.60.50.50.30.7-0.90.50.30.3-0.50.4-0.40.4-0.6-0.70.30.50.20.20.30.3
Total locomotion distance, hab. session 20.20.31.00.6-0.6-0.6-0.5-0.4-1.00.4-0.5-0.6-0.50.5-0.40.4-0.50.51.0-0.4-0.0-0.50.1-0.5-0.5
Locomotion velocity, hab. session 20.40.51.30.8-0.8-0.7-0.7-0.6-1.10.7-0.7-0.7-0.70.7-0.60.6-0.70.71.2-0.6-0.3-0.6-0.1-0.7-0.6
Novel to familiar place preference ratio0.80.81.0-0.90.91.01.00.90.7-0.80.80.90.8-1.01.0-1.00.9-0.9-0.81.01.01.01.01.00.8
Novelty place preference0.91.01.5-1.00.91.01.01.00.5-0.80.91.00.9-1.01.1-1.11.0-0.9-0.61.11.11.11.21.10.9
Time in novel zone, NPP test0.40.40.6-0.60.60.60.60.60.3-0.50.50.60.6-0.60.7-0.70.6-0.6-0.40.70.70.70.70.60.5
Total zone transitions, NPP test0.40.61.60.9-0.6-0.8-0.7-0.8-0.50.2-0.4-1.0-0.90.8-0.90.9-0.90.50.5-1.0-0.4-1.3-0.6-1.0-0.9
Total locomotion distance, NPP test0.30.50.80.8-0.7-0.7-0.7-0.6-0.80.5-0.4-0.7-0.60.7-0.70.7-0.70.60.8-0.7-0.3-0.9-0.3-0.8-0.7
Locomotion velocity, NPP test0.20.30.70.6-0.6-0.6-0.5-0.4-0.80.4-0.4-0.5-0.50.5-0.50.5-0.50.50.8-0.5-0.1-0.6-0.0-0.6-0.5
Pavlov. Cond. lever latency0.10.21.00.2-0.5-0.3-0.2-0.2-1.00.6-0.6-0.2-0.00.20.1-0.1-0.10.40.90.20.00.30.50.00.0
Pavlov. Cond. magazine entry latency0.10.10.6-0.20.10.20.1-0.20.80.2-0.30.20.1-0.10.1-0.10.10.1-0.70.1-0.70.4-0.80.30.1
Pavlov. Cond. change in total contacts0.00.00.30.00.0-0.0-0.1-0.10.4-0.00.0-0.0-0.30.1-0.20.2-0.10.0-0.3-0.2-0.3-0.2-0.5-0.1-0.2
Pavlov. Cond. index score0.10.11.0-0.30.40.30.10.01.0-0.20.20.20.0-0.20.0-0.00.2-0.2-0.9-0.0-0.40.1-0.80.10.0
Pavlov. Cond. latency score0.10.10.8-0.20.30.20.10.00.9-0.20.20.20.0-0.20.00.00.1-0.2-0.8-0.0-0.30.0-0.70.10.0
Pavlov. Cond. lever contacts0.30.41.5-0.60.80.70.60.51.2-0.90.80.60.4-0.60.4-0.40.6-0.7-1.20.30.30.3-0.10.50.5
Pavlov. Cond. magazine entry number0.10.11.00.1-0.1-0.10.10.3-0.8-0.10.2-0.10.10.00.1-0.10.0-0.10.80.20.8-0.01.0-0.00.1
Pavlov. Cond. intertrial magazine entries8.610.312.03.3-3.2-3.2-3.2-3.4-2.53.1-3.3-3.5-3.53.2-3.33.3-3.33.22.7-3.3-2.9-3.3-2.7-3.3-3.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.8-0.20.30.20.1-0.00.9-0.10.10.2-0.0-0.20.0-0.00.1-0.1-0.8-0.0-0.50.1-0.80.10.0
Pavlov. Cond. response bias0.10.21.2-0.10.20.1-0.1-0.31.0-0.1-0.0-0.0-0.10.0-0.20.2-0.1-0.0-0.9-0.3-0.7-0.2-1.1-0.1-0.2
Bone: apparent density0.00.00.10.2-0.2-0.2-0.2-0.3-0.20.2-0.3-0.2-0.20.2-0.20.2-0.20.20.1-0.2-0.2-0.1-0.2-0.2-0.2
Bone surface0.20.40.9-0.60.40.60.60.60.0-0.40.30.60.6-0.60.8-0.80.6-0.5-0.10.80.70.90.90.70.8
Bone volume0.20.30.9-0.50.30.40.50.5-0.2-0.20.20.60.6-0.50.7-0.70.5-0.30.20.70.60.80.90.60.7
Bone: connectivity density0.40.60.60.8-0.8-0.8-0.8-0.8-0.70.8-0.8-0.8-0.80.8-0.80.8-0.80.80.7-0.8-0.7-0.8-0.7-0.8-0.8
Bone: cortical apparent density4.25.48.42.5-2.5-2.5-2.4-2.0-2.92.6-2.1-2.2-2.22.5-2.32.3-2.42.42.9-2.2-1.8-2.3-1.2-2.3-2.3
Bone: cortical area0.20.41.40.5-0.7-0.5-0.5-0.9-0.50.9-1.2-0.7-0.60.5-0.30.3-0.50.70.7-0.2-0.7-0.0-0.3-0.3-0.4
Bone: cortical porosity0.20.30.70.5-0.6-0.5-0.5-0.4-0.80.7-0.5-0.4-0.50.5-0.40.4-0.50.60.8-0.3-0.4-0.3-0.1-0.4-0.4
Bone: cortical porosity0.20.20.40.4-0.5-0.5-0.5-0.5-0.30.6-0.6-0.5-0.50.5-0.50.5-0.50.50.3-0.5-0.6-0.4-0.6-0.4-0.4
Bone: cortical thickness0.71.22.61.0-1.1-1.0-1.1-1.5-0.41.3-1.6-1.3-1.21.0-1.01.0-1.01.20.5-1.0-1.4-0.8-1.3-0.9-1.1
Bone: cortical thickness0.70.81.80.9-1.1-0.9-0.8-1.0-1.21.2-1.2-1.0-0.90.8-0.70.6-0.81.01.3-0.6-0.6-0.5-0.2-0.7-0.9
Bone: cortical tissue density4.15.38.72.5-2.5-2.5-2.4-2.0-2.92.5-2.1-2.1-2.12.5-2.32.2-2.42.42.9-2.2-1.7-2.3-1.2-2.3-2.3
Bone: elastic displacement0.20.21.0-0.0-0.2-0.00.10.4-0.90.40.10.30.3-0.00.3-0.30.10.11.00.40.40.50.90.30.1
Bone: elastic work0.81.03.0-0.90.60.80.91.2-0.2-0.50.91.11.1-0.91.2-1.21.0-0.70.31.31.31.31.71.11.1
Bone: endosteal estimation1.42.96.3-1.61.31.51.71.90.2-1.11.41.81.8-1.62.0-2.01.7-1.4-0.12.12.02.12.51.92.0
Bone: endosteal perimeter0.20.40.8-0.60.50.60.60.40.2-0.40.20.50.5-0.60.8-0.80.7-0.5-0.20.80.60.90.80.70.8
Bone: final force0.20.31.1-0.4-0.00.30.30.3-0.50.3-0.20.50.5-0.40.7-0.70.4-0.00.60.80.31.01.00.70.6
Bone: final moment0.10.20.7-0.2-0.20.10.10.0-0.70.6-0.40.30.3-0.10.4-0.50.20.20.80.60.10.90.70.50.4
Bone: marrow area1.42.96.4-1.61.21.51.61.90.1-1.11.41.81.8-1.62.0-2.01.7-1.4-0.12.12.02.12.51.91.9
Bone: maximum diameter0.10.20.6-0.50.40.50.50.10.5-0.3-0.00.30.3-0.60.6-0.60.5-0.4-0.40.60.30.80.40.60.5
Bone: maximum force0.10.10.3-0.0-0.3-0.0-0.0-0.1-0.40.5-0.50.10.1-0.00.2-0.20.10.30.60.3-0.10.50.30.20.3
Bone: maximum moment0.10.10.50.2-0.4-0.2-0.2-0.3-0.50.7-0.7-0.1-0.10.20.0-0.0-0.10.50.60.1-0.40.40.00.00.1
Bone: minimum diameter0.51.02.00.9-1.2-1.0-1.0-1.1-1.31.4-1.4-0.9-0.90.9-0.70.7-0.91.21.3-0.6-0.9-0.4-0.4-0.7-0.7
Bone: periosteal estimation0.30.72.2-0.70.30.70.70.7-0.3-0.10.20.80.8-0.81.1-1.10.8-0.40.41.20.91.41.51.01.0
Bone: periosteal perimeter0.00.00.1-0.1-0.00.10.1-0.10.10.1-0.30.00.0-0.10.2-0.20.10.00.00.2-0.10.40.10.20.2
Bone: post-yield work2.12.83.81.7-1.8-1.7-1.7-1.8-1.42.0-2.0-1.6-1.61.7-1.61.6-1.71.81.4-1.6-1.9-1.4-1.6-1.6-1.6
Bone: stiffness1.01.62.91.3-1.4-1.3-1.3-1.5-1.21.5-1.7-1.4-1.31.2-1.11.1-1.21.41.3-1.1-1.2-1.0-0.9-1.2-1.1
Bone: tissue strength0.30.30.6-0.50.30.40.40.60.0-0.10.30.70.7-0.50.6-0.60.5-0.3-0.00.70.40.80.60.60.7
Bone: trabecular number0.30.40.60.7-0.7-0.7-0.7-0.7-0.80.7-0.7-0.7-0.70.7-0.60.6-0.70.70.7-0.6-0.5-0.6-0.4-0.7-0.7
Bone: trabecular spacing0.00.10.1-0.30.20.20.20.20.3-0.00.10.30.3-0.20.2-0.20.2-0.1-0.30.3-0.00.40.00.30.2
Bone: trabecular thickness0.00.10.10.3-0.2-0.3-0.2-0.1-0.30.1-0.0-0.2-0.20.3-0.30.3-0.30.20.3-0.3-0.1-0.4-0.1-0.3-0.2
Bone: trabecular tissue density0.00.00.1-0.0-0.0-0.0-0.0-0.10.20.1-0.2-0.1-0.00.0-0.00.0-0.00.1-0.1-0.0-0.20.1-0.20.0-0.0
Breakpoint value in progressive ratio session0.10.11.0-0.00.20.1-0.0-0.41.0-0.3-0.2-0.2-0.2-0.0-0.10.2-0.0-0.1-0.8-0.2-0.5-0.2-0.8-0.1-0.1
Distance traveled before self-admin0.91.01.5-0.91.11.01.01.01.0-1.21.20.90.9-1.00.9-0.91.0-1.1-0.80.91.20.81.00.91.0
Distance traveled after self-admin0.10.10.70.3-0.5-0.4-0.3-0.2-0.80.5-0.3-0.2-0.20.3-0.20.2-0.30.40.8-0.1-0.0-0.10.3-0.2-0.1
Delta time in closed arm before/after self-admin0.10.10.20.3-0.2-0.3-0.3-0.2-0.20.0-0.1-0.2-0.30.3-0.30.3-0.30.20.2-0.3-0.2-0.4-0.3-0.3-0.0
Delta time in open arm before/after self-admin1.11.11.71.0-1.0-1.0-1.0-1.2-0.61.1-1.2-1.1-1.11.0-1.01.0-1.01.00.3-1.0-1.2-0.9-1.1-1.0-1.3
Diff in mean of infusions in LGA sessions0.91.03.70.7-0.5-0.6-0.8-1.40.60.5-1.2-1.2-1.10.7-1.01.0-0.80.7-0.4-1.1-1.5-1.0-1.9-0.9-1.0
Extinction: sum of active levers before priming0.10.10.4-0.10.10.10.0-0.20.60.1-0.2-0.1-0.0-0.10.0-0.00.1-0.0-0.6-0.0-0.30.1-0.40.1-0.2
Active lever presses in extinction session 61.51.41.91.2-1.2-1.2-1.2-1.3-1.01.3-1.4-1.2-1.11.2-1.21.1-1.21.21.1-1.1-1.2-1.1-1.0-1.2-1.3
Delta distance traveled before/after self-admin0.50.51.30.7-0.9-0.7-0.7-0.7-1.21.1-1.0-0.6-0.60.7-0.60.5-0.70.90.9-0.5-0.8-0.3-0.4-0.5-0.6
Delta ambulatory time before/after self-admin1.21.33.51.1-1.4-1.2-1.2-1.0-1.91.7-1.4-0.9-0.91.2-0.90.9-1.11.41.6-0.8-1.0-0.7-0.5-0.9-1.0
Time in closed arm before self-admin7.99.110.2-3.13.03.03.13.02.3-3.03.03.13.1-3.13.1-3.13.1-3.0-2.23.13.23.13.03.13.0
Time in closed arm after self-admin6.77.011.4-2.52.32.52.63.01.0-2.42.82.82.8-2.52.8-2.82.6-2.5-0.92.93.22.73.42.72.9
Time in open arm before self-admin6.16.57.72.7-2.6-2.7-2.6-2.2-2.62.4-2.3-2.5-2.62.7-2.72.7-2.72.52.6-2.7-2.2-2.8-1.9-2.7-2.4
Time in open arm after self-admin10.411.414.13.4-3.2-3.3-3.4-3.7-1.93.2-3.5-3.6-3.63.4-3.63.6-3.53.31.8-3.6-3.7-3.5-3.8-3.5-3.5
Sum of active levers in priming session hrs 5-60.30.31.0-0.50.60.60.50.21.0-0.60.30.30.4-0.50.4-0.40.5-0.5-1.00.40.20.5-0.00.50.4
Time to tail flick, vehicle, before self-admin2.32.44.21.6-1.3-1.5-1.5-1.6-0.91.2-1.3-1.7-1.61.5-1.71.7-1.61.30.8-1.8-1.3-1.9-1.6-1.8-2.1
Time to tail flick, vehicle, after self-admin0.90.91.60.9-0.8-0.9-1.0-1.0-0.20.6-0.8-1.0-1.10.9-1.11.1-1.00.80.3-1.2-1.1-1.2-1.3-1.1-1.0
Time to tail flick, test, before self-admin0.10.10.4-0.30.20.20.30.2-0.0-0.20.20.30.4-0.30.4-0.40.3-0.20.20.40.40.40.60.30.3
Time to tail flick, test, after self-admin5.05.16.42.3-2.1-2.3-2.3-2.2-1.52.0-2.1-2.4-2.42.3-2.52.5-2.32.21.6-2.5-2.4-2.5-2.5-2.4-2.3
Delta time to tail flick, vehicle, before/after SA0.20.20.80.4-0.5-0.4-0.5-0.6-0.00.5-0.7-0.4-0.50.4-0.40.4-0.40.60.2-0.4-0.9-0.2-0.8-0.3-0.2
Delta time to tail flick, test, before/after SA5.14.66.02.2-2.0-2.2-2.2-2.1-1.31.9-1.9-2.2-2.32.2-2.32.4-2.22.01.5-2.4-2.2-2.4-2.3-2.3-2.2
Ambulatory time before self-admin1.21.32.8-1.11.31.21.21.01.4-1.71.30.91.0-1.11.0-1.01.1-1.3-1.20.91.30.80.91.01.2
Ambulatory time after self-admin0.20.20.4-0.40.30.30.40.40.0-0.30.40.40.4-0.40.4-0.40.4-0.3-0.10.50.50.50.70.40.6
Total heroin consumption2.53.05.21.6-1.5-1.6-1.7-2.0-0.31.5-1.8-2.0-2.01.6-1.81.8-1.71.60.5-1.9-2.0-1.8-2.3-1.8-1.7
Area under the delay curve1.31.43.1-1.11.01.11.21.40.4-0.91.41.41.3-1.11.3-1.31.2-1.1-0.41.31.61.21.81.20.9
Delay disc. indifference point, 0s delay0.40.40.70.7-0.7-0.7-0.6-0.6-0.60.8-0.6-0.6-0.70.7-0.60.6-0.70.60.4-0.6-0.5-0.7-0.4-0.6-0.8
Delay disc. indifference point, 16s delay1.61.63.0-1.21.11.21.31.40.7-1.11.51.41.4-1.21.3-1.31.3-1.3-0.41.41.61.31.71.31.1
Delay disc. indifference point, 2s delay3.84.27.1-2.01.81.92.12.30.8-1.72.02.22.2-2.02.2-2.22.1-1.9-0.82.32.42.32.72.22.0
Delay disc. indifference point, 24s delay1.31.32.5-1.01.01.01.11.20.6-1.21.41.21.1-1.11.2-1.21.1-1.2-0.51.21.61.01.61.11.0
Delay disc. indifference point, 4s delay0.60.62.7-0.50.40.50.61.0-0.5-0.50.90.80.7-0.50.7-0.70.6-0.60.60.81.30.61.70.70.6
Delay disc. indifference point, 8s delay0.50.51.2-0.60.60.60.70.90.1-0.60.90.80.7-0.60.7-0.70.6-0.7-0.40.71.00.61.10.70.4
Delay discount exponential model param1.11.22.71.0-0.9-0.9-1.1-1.3-0.20.9-1.3-1.2-1.11.0-1.11.1-1.01.00.2-1.2-1.5-1.0-1.7-1.1-0.8
Delay discount hyperbolic model param1.41.53.31.1-1.1-1.1-1.2-1.4-0.41.0-1.4-1.4-1.31.2-1.31.3-1.21.20.3-1.3-1.7-1.2-1.8-1.2-1.0
Fecal boli incidents, locomotor time 10.40.52.9-0.70.80.70.50.31.7-0.70.40.50.4-0.60.4-0.40.5-0.6-1.40.3-0.10.4-0.60.50.2
Change in fecal boli incidents, locomotor task1.81.74.41.4-1.4-1.4-1.3-1.1-2.11.2-1.0-1.2-1.21.4-1.21.2-1.31.31.8-1.2-0.6-1.4-0.3-1.3-1.1
Time >=10cm from walls, locomotor time 12.82.87.81.5-1.1-1.4-1.6-2.00.40.8-1.4-1.8-1.81.5-1.91.9-1.61.3-0.3-2.1-2.1-2.1-2.8-1.9-1.7
Bouts of movement, locomotor time 11.11.21.9-1.21.31.31.21.01.4-1.10.91.01.0-1.21.1-1.11.2-1.2-1.41.10.91.10.61.20.9
Total resting periods, locomotor time 11.31.41.8-1.31.31.31.31.11.3-1.01.01.21.1-1.31.3-1.31.3-1.2-1.31.21.01.30.81.31.0
Rest time, locomotor task time 10.40.51.6-0.60.50.60.70.8-0.2-0.50.70.50.7-0.60.8-0.70.7-0.7-0.10.81.10.61.30.60.5
Distance moved, locomotor task time 10.91.01.4-1.10.91.01.01.00.8-0.90.91.11.2-1.01.1-1.11.0-0.9-0.71.10.81.20.91.11.2
Vertical activity count, locomotor time 10.10.10.2-0.30.20.20.20.4-0.0-0.30.40.40.3-0.20.3-0.30.2-0.20.10.30.30.30.30.30.4
Time >=10cm from walls, locomotor time 22.52.75.11.6-1.4-1.5-1.6-1.7-0.51.3-1.6-1.7-1.81.6-1.81.8-1.61.50.5-1.9-2.0-1.8-2.3-1.8-1.9
Bouts of movement, locomotor time 20.40.42.70.1-0.5-0.2-0.00.1-1.70.9-0.30.10.20.10.3-0.30.00.31.30.50.50.51.40.20.0
Total resting periods, locomotor time 20.40.42.4-0.0-0.3-0.10.10.3-1.40.60.00.30.4-0.10.5-0.50.20.11.20.60.80.61.50.40.2
Rest time, locomotor task time 20.10.10.8-0.10.10.10.30.3-0.1-0.20.40.10.3-0.20.3-0.30.2-0.30.30.30.80.10.90.20.0
Distance moved, locomotor task time 20.40.40.8-0.70.70.70.70.50.9-0.80.50.70.6-0.70.7-0.70.7-0.6-0.80.60.30.70.20.70.8
Vertical activity count, locomotor time 20.10.10.20.2-0.2-0.2-0.2-0.3-0.30.2-0.4-0.3-0.30.2-0.20.2-0.20.30.0-0.2-0.4-0.2-0.4-0.2-0.1
Weight adjusted by age0.10.10.30.5-0.4-0.4-0.4-0.3-0.30.3-0.1-0.3-0.40.4-0.40.4-0.40.30.6-0.40.0-0.50.1-0.5-0.3
Seeking ratio, delayed vs. immediate footshock0.40.40.60.7-0.6-0.6-0.6-0.8-0.50.7-0.7-0.8-0.60.6-0.60.6-0.60.60.4-0.6-0.6-0.6-0.6-0.7-0.6
Locomotion in novel chamber3.13.99.22.1-2.3-2.2-2.0-1.5-2.92.2-1.7-1.8-1.72.1-1.81.8-2.02.13.0-1.7-1.1-1.8-0.4-1.9-1.8
Locomotion in novel chamber post-restriction0.20.20.6-0.40.30.40.40.6-0.2-0.30.30.60.5-0.40.5-0.50.4-0.40.00.60.60.60.80.50.5
Progressive ratio1.61.85.6-1.10.81.01.21.7-0.7-0.51.21.41.5-1.11.5-1.51.2-1.00.41.61.81.62.41.41.4
Food seeking constrained by brief footshock0.10.10.40.2-0.3-0.2-0.1-0.1-0.50.5-0.4-0.2-0.10.10.0-0.0-0.10.30.70.10.10.10.4-0.0-0.2
Seeking ratio, punishment vs. effort1.01.32.81.0-0.9-0.9-1.1-1.50.20.7-1.2-1.2-1.31.0-1.21.2-1.11.00.2-1.3-1.4-1.2-1.7-1.2-1.3
Run reversals in cocaine runway, females2.82.73.9-1.71.51.71.71.80.9-1.21.41.71.8-1.71.8-1.91.8-1.5-0.91.91.62.01.71.91.7
Run reversals in cocaine runway, males0.10.10.2-0.10.10.10.10.5-0.1-0.20.30.30.3-0.10.2-0.20.2-0.10.20.20.30.20.40.20.4
Latency to leave start box in cocaine runway0.80.91.7-0.90.80.91.01.00.2-0.80.91.01.0-1.01.1-1.11.0-0.9-0.41.11.21.11.31.01.0
Latency to leave start box in cocaine runway, F0.30.30.4-0.60.60.60.60.40.5-0.60.50.50.5-0.60.5-0.50.6-0.6-0.70.50.50.50.30.60.5
Latency to leave start box in cocaine runway, M0.70.71.3-0.80.70.80.90.80.4-0.70.70.80.8-0.91.0-1.00.9-0.8-0.41.01.01.01.20.90.8
Cd content in liver0.70.82.61.0-1.0-1.0-0.8-0.5-1.60.8-0.5-0.7-0.70.9-0.70.8-0.90.81.6-0.7-0.1-0.90.2-0.9-0.7
Co content in liver1.01.21.61.2-1.2-1.1-1.1-1.2-1.11.1-1.3-1.3-1.31.1-1.01.0-1.11.11.1-1.1-0.9-1.1-0.7-1.1-1.2
Cu content in liver2.53.03.7-1.81.81.81.81.61.7-1.91.61.71.7-1.81.8-1.81.8-1.8-1.81.71.61.71.31.81.8
Fe content in liver1.01.21.8-1.21.01.11.11.00.9-0.90.91.21.2-1.11.2-1.21.1-1.0-0.91.20.81.30.91.21.2
K content in liver1.01.01.91.0-0.8-0.9-1.0-1.0-0.20.6-0.7-1.1-1.11.0-1.21.2-1.00.80.2-1.2-1.1-1.3-1.4-1.1-1.1
Mg content in liver0.10.10.30.4-0.4-0.4-0.4-0.2-0.30.3-0.1-0.3-0.30.4-0.50.5-0.40.30.3-0.4-0.3-0.5-0.3-0.4-0.3
Mn content in liver0.20.31.00.4-0.7-0.5-0.5-0.3-1.00.9-0.6-0.2-0.20.5-0.30.3-0.40.70.9-0.2-0.5-0.1-0.1-0.3-0.3
Na content in liver0.10.10.7-0.10.30.20.1-0.10.8-0.30.1-0.0-0.0-0.1-0.10.10.1-0.1-0.8-0.2-0.3-0.1-0.7-0.0-0.1
Rb content in liver0.30.41.30.7-0.7-0.7-0.5-0.5-1.00.6-0.6-0.6-0.60.6-0.40.4-0.60.61.1-0.4-0.0-0.50.3-0.6-0.5
Se content in liver0.00.00.1-0.10.20.10.10.20.1-0.40.30.10.0-0.10.0-0.00.1-0.2-0.2-0.00.3-0.10.10.00.1
Sr content in liver0.20.21.2-0.00.00.10.20.2-0.6-0.30.20.00.0-0.20.3-0.30.2-0.20.60.30.90.21.10.20.2
Zn content in liver0.10.10.5-0.1-0.00.10.10.2-0.4-0.00.10.20.1-0.10.2-0.20.1-0.10.50.30.50.20.70.20.1