Hub : Genes

Entpd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000014574 0.11 0.06 3.7e-12 0.09 0.08 0.09 0.1 2.0e-10 1.9e-09 1.9e-10 7.9e-11
2 BLA gene expression ENSRNOG00000014574 0.09 0.06 1.6e-03 0.03 0.03 0.02 0.03 9.8e-03 8.7e-03 3.6e-02 7.4e-03
3 Brain alternative TSS ENSRNOT00000019751 0.03 0.02 4.6e-03 0.02 0.02 0.01 0.02 4.2e-03 8.8e-03 8.8e-02 1.0e-02
4 Brain alternative TSS ENSRNOT00000115487 0.03 0.02 7.0e-03 0.02 0.02 0 0.01 5.6e-03 1.2e-02 1.9e-01 1.4e-02
5 Brain gene expression ENSRNOG00000014574 0.09 0.05 5.1e-09 0.07 0.09 0.09 0.09 1.8e-07 1.9e-08 1.8e-08 2.5e-08
6 Liver gene expression ENSRNOG00000014574 0.05 0.04 6.6e-03 0.01 0 0 0 1.4e-02 1.1e-01 1.9e-01 8.3e-02
7 NAcc alternative TSS ENSRNOT00000115487 0.11 0.07 3.4e-08 0.13 0.1 0.13 0.12 6.9e-10 7.6e-08 3.6e-10 1.6e-09
8 NAcc alternative TSS ENSRNOT00000115846 0.03 0.03 6.6e-03 0.02 0.03 0.02 0.02 1.2e-02 4.7e-03 2.2e-02 1.9e-02
9 NAcc alternative TSS ENSRNOT00000019751 0.1 0.06 8.7e-08 0.09 0.08 0.08 0.1 3.0e-07 9.3e-07 2.5e-06 5.2e-08
10 NAcc alternative TSS ENSRNOT00000115487 0.11 0.06 2.7e-08 0.1 0.09 0.08 0.11 8.5e-08 3.8e-07 1.6e-06 2.0e-08
11 NAcc gene expression ENSRNOG00000014574 0.42 0.14 0.0e+00 0.45 0.47 0.47 0.48 9.2e-37 2.2e-39 7.7e-39 2.8e-40
12 NAcc intron excision ratio chr1:239473951:239521887 0.03 0.02 7.2e-03 0.04 0.03 0.03 0.03 1.1e-03 3.7e-03 5.1e-03 3.4e-03
13 NAcc mRNA stability ENSRNOG00000014574 0.07 0.05 4.1e-04 0.05 0.04 0.05 0.06 1.5e-04 8.4e-04 8.2e-05 6.5e-05
14 OFC gene expression ENSRNOG00000014574 0.23 0.12 3.7e-05 0.15 0.19 0.18 0.19 2.0e-04 3.3e-05 4.1e-05 3.0e-05
15 PL mRNA stability ENSRNOG00000014574 0.08 0.05 1.2e-05 0.05 0.07 0.06 0.07 7.3e-05 4.1e-06 1.7e-05 2.8e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.92.84.6-0.82.01.7-1.71.6-1.2-1.61.21.7-1.71.81.6-2.11.7-2.1
BMI without tail1.22.54.3-1.32.11.6-1.61.5-0.8-1.21.51.5-1.62.01.3-1.81.8-1.9
Body weight0.51.93.3-0.31.61.6-1.60.8-0.5-1.81.11.6-1.61.81.4-1.21.6-1.1
Epididymis fat weight1.73.95.0-1.52.22.1-2.11.7-1.6-1.71.92.1-2.12.21.9-2.02.2-2.0
Glucose0.10.21.1-0.60.20.3-0.30.2-1.00.20.60.3-0.30.40.3-0.30.4-0.3
Heart weight0.10.20.7-0.30.10.3-0.3-0.1-0.8-0.30.50.5-0.50.50.4-0.20.40.2
Left kidney weight0.20.73.40.1-0.7-0.10.1-0.91.4-0.60.1-0.20.2-0.0-0.31.70.01.8
Right kidney weight0.41.15.50.8-1.1-0.20.2-1.61.2-0.3-0.3-0.30.3-0.3-0.32.1-0.32.4
Tail length0.10.20.50.00.30.5-0.5-0.50.5-0.30.60.4-0.40.70.20.60.60.6
Length with tail0.20.62.70.8-0.7-0.00.0-1.11.1-0.6-0.1-0.10.1-0.1-0.21.6-0.01.6
Length without tail0.30.72.51.2-1.1-0.30.3-1.10.8-0.5-0.6-0.30.3-0.6-0.21.4-0.51.6
Liver weight, left0.10.20.8-0.90.40.3-0.30.7-0.4-0.50.70.3-0.30.40.2-0.30.5-0.3
Liver weight, right0.71.21.9-0.90.91.2-1.20.9-0.8-1.41.21.3-1.31.21.2-0.71.2-0.5
Parametrial fat weight0.20.30.9-0.50.20.6-0.60.1-0.2-0.40.90.7-0.70.90.50.10.70.4
Retroperitoneal fat weight0.62.13.3-0.61.41.6-1.60.8-1.4-1.31.31.6-1.71.71.5-1.31.8-1.2
Intraocular pressure0.20.21.0-0.50.50.2-0.20.6-0.4-1.00.10.5-0.50.40.5-0.50.2-0.5
Extensor digitorum longus weight0.10.20.90.90.70.5-0.5-0.20.6-0.6-0.00.4-0.40.60.4-0.00.6-0.0
Soleus weight0.71.93.0-1.61.61.3-1.31.7-0.7-1.41.51.4-1.41.51.3-1.11.5-1.3
Tibialis anterior weight0.10.51.10.21.00.8-0.80.30.6-0.90.40.7-0.70.90.6-0.30.9-0.4
Tibia length0.00.00.1-0.0-0.10.0-0.0-0.1-0.40.10.30.0-0.00.2-0.0-0.10.40.1
Number of licking bursts2.22.63.61.4-1.5-1.71.7-1.31.11.8-1.8-1.91.9-1.9-1.81.1-1.80.8
Food consumed during 24 hour testing period0.70.91.70.5-1.2-1.01.0-0.71.10.3-0.7-1.01.0-1.0-0.91.3-1.01.2
Times rat made contact with spout0.40.40.7-0.2-0.6-0.80.8-0.00.80.6-0.4-0.80.8-0.8-0.80.5-0.70.2
Mean time between licks in bursts0.10.10.3-0.50.30.4-0.40.4-0.1-0.20.60.4-0.40.40.3-0.30.4-0.4
Mean num. licks in bursts2.02.43.3-1.81.51.5-1.51.6-0.9-1.61.81.7-1.71.71.6-1.11.7-1.0
Std. dev. time between licks in bursts0.30.30.50.5-0.6-0.60.6-0.50.20.6-0.6-0.70.7-0.7-0.60.2-0.70.2
Water consumed over 24 hours0.30.40.90.0-0.6-0.70.70.11.00.2-0.5-0.70.8-0.8-0.70.5-0.80.2
Indifference point 0 sec0.10.10.5-0.0-0.5-0.30.3-0.4-0.10.4-0.0-0.30.3-0.3-0.30.6-0.30.7
Indifference point AUC3.23.76.51.5-2.5-2.02.0-1.70.92.1-1.8-2.02.1-2.3-1.91.5-2.31.6
Indifference point function ln k2.73.96.4-1.52.52.2-2.21.7-0.7-2.21.72.1-2.22.32.0-1.62.2-1.7
Indifference point function log k2.73.96.4-1.52.52.2-2.21.7-0.7-2.21.72.1-2.22.32.0-1.62.2-1.7
Delay discounting total patch changes 0 sec0.00.10.3-0.2-0.4-0.10.1-0.2-0.10.10.1-0.10.1-0.1-0.10.5-0.10.6
Delay discounting total patch changes 12 sec2.53.35.11.4-2.3-2.02.0-1.61.02.1-1.6-2.02.0-2.1-1.81.5-2.01.7
Delay discounting total patch changes 18 sec0.50.71.40.4-1.1-0.90.9-0.4-0.71.0-0.8-0.90.9-1.2-0.8-0.1-1.20.1
Delay discounting total patch changes 24 sec0.20.30.7-0.1-0.9-0.30.3-0.2-0.70.8-0.1-0.50.5-0.6-0.50.0-0.70.3
Delay discounting total patch changes 6 sec2.64.06.41.5-2.5-2.02.0-2.00.82.1-1.7-2.12.1-2.3-2.01.9-2.22.1
Delay discounting time to switch 0 sec0.50.71.10.6-0.8-1.01.0-0.60.61.0-1.0-1.01.0-0.9-1.00.5-0.90.5
Delay discounting water rate 0 sec1.32.03.0-0.91.31.7-1.71.0-1.5-1.61.31.7-1.71.51.7-1.21.3-1.0
Delay discounting water rate 12 sec0.30.40.8-0.10.60.8-0.80.2-0.2-0.90.60.7-0.70.80.6-0.20.8-0.0
Delay discounting water rate 18 sec0.20.30.5-0.10.50.7-0.70.00.1-0.70.40.7-0.70.70.60.10.50.1
Delay discounting water rate 24 sec0.50.72.2-0.30.81.1-1.10.4-0.2-1.50.51.0-1.00.91.0-0.30.8-0.4
Delay discounting water rate 6 sec0.20.30.5-0.60.50.7-0.70.6-0.6-0.60.50.6-0.50.60.6-0.60.4-0.5
Locomotor activity0.00.00.4-0.20.10.2-0.20.1-0.6-0.20.20.1-0.10.20.1-0.10.20.1
Locomotor testing distance0.10.11.0-0.50.10.3-0.30.3-1.0-0.10.40.2-0.20.30.2-0.30.2-0.1
Locomotor testing rearing0.40.61.4-0.60.80.7-0.70.8-1.2-0.30.70.7-0.70.60.7-1.00.6-1.0
Light reinforcement 10.10.20.4-0.0-0.3-0.40.40.00.70.5-0.3-0.40.4-0.6-0.40.2-0.40.1
Light reinforcement 22.33.04.31.4-1.8-1.81.8-1.51.81.6-1.9-1.81.8-2.1-1.71.6-1.71.4
Reaction time number correct0.81.12.3-0.41.51.2-1.21.0-0.5-1.10.71.1-1.11.10.9-1.10.9-1.4
Reaction time mean minus median0.30.41.1-0.80.40.5-0.50.60.5-0.51.00.6-0.60.60.6-0.10.8-0.1
Reaction time mean minus median AUC0.40.41.0-0.70.60.7-0.70.60.1-0.71.00.7-0.70.70.7-0.41.0-0.3
Reaction time num false alarms0.10.21.51.2-0.10.1-0.1-0.70.00.0-0.30.2-0.20.00.30.2-0.20.3
Reaction time num false alarms AUC0.10.10.70.8-0.00.3-0.3-0.5-0.2-0.2-0.00.4-0.40.20.50.20.10.3
Reaction time trials correct on left0.81.12.3-0.41.51.2-1.21.0-0.5-1.10.71.1-1.11.10.9-1.10.9-1.4
Reaction time trials on left0.81.12.3-0.41.51.1-1.11.0-0.5-1.20.71.1-1.11.10.9-1.01.0-1.3
Reaction time mean0.20.30.90.5-0.7-0.50.5-0.60.90.6-0.2-0.40.5-0.5-0.30.8-0.30.9
Reaction time mean AUC0.50.61.20.8-0.9-0.70.7-0.91.10.9-0.4-0.70.7-0.7-0.61.0-0.51.1
Median of all reaction times0.30.40.80.6-0.8-0.60.6-0.70.70.8-0.4-0.50.6-0.6-0.50.8-0.50.9
Reaction time omissions1.11.42.8-1.41.11.2-1.21.1-0.3-1.31.71.3-1.41.41.2-0.51.4-0.5
Reaction time false alarm rate0.20.31.11.0-0.7-0.20.2-0.90.10.4-0.4-0.10.1-0.3-0.00.6-0.40.9
Reaction time premature initiation rate0.10.10.70.3-0.5-0.20.2-0.40.00.30.0-0.30.3-0.2-0.20.4-0.20.9
Reaction time premature initiations0.10.10.20.10.30.4-0.40.1-0.1-0.30.40.3-0.30.40.3-0.00.30.2
Std. dev. reaction times0.20.20.9-0.60.10.3-0.30.40.6-0.41.00.4-0.40.50.50.20.70.3
Reaction time trials completed0.81.12.3-0.41.51.1-1.11.0-0.5-1.20.71.1-1.11.10.9-1.01.0-1.3
Reaction time trials AUC0.71.02.2-0.21.51.1-1.10.9-0.5-1.20.61.0-1.11.10.9-1.00.9-1.3
Social response proportion1.41.53.8-1.91.50.8-0.81.9-0.4-1.01.10.9-0.91.10.9-1.30.9-1.7
Social responses1.82.35.7-2.41.41.4-1.42.0-1.3-1.01.71.4-1.31.31.4-1.61.2-1.6
Social time0.10.10.5-0.7-0.1-0.00.00.20.50.10.3-0.10.1-0.1-0.10.4-0.20.4
Conditioned locomotion1.61.92.7-0.51.61.6-1.60.8-1.1-1.21.01.6-1.61.61.5-1.41.6-1.5
Cocaine response after cond. corrected0.10.10.30.2-0.3-0.10.1-0.10.4-0.1-0.5-0.10.2-0.4-0.00.1-0.40.1
Cocaine response after cond. not corrected0.30.30.90.3-0.7-0.50.5-0.41.00.0-0.5-0.50.5-0.6-0.40.9-0.60.7
Cocaine response before conditioning1.31.53.30.6-1.3-1.31.3-1.11.51.0-0.7-1.21.2-1.1-1.21.8-1.11.7
Saline control response2.02.64.02.0-1.8-1.61.6-1.90.61.8-1.7-1.61.6-1.7-1.51.2-1.61.6
Condit. Reinf. active minus inactive responses2.02.43.2-0.81.81.7-1.71.3-1.4-1.41.41.8-1.81.71.7-1.51.7-1.5
Condit. Reinf. active-inactive response ratio0.91.01.7-0.41.31.0-1.00.7-0.7-0.90.81.2-1.21.21.1-0.91.2-0.9
Condit. Reinf. active responses1.52.12.9-0.81.41.6-1.61.0-1.7-1.31.41.7-1.71.61.7-1.31.6-1.0
Condit. Reinf. inactive responses0.20.21.0-0.1-0.00.6-0.6-0.1-1.0-0.50.60.5-0.50.50.6-0.10.50.2
Condit. Reinf. lever presses0.10.20.5-0.4-0.5-0.30.3-0.20.60.10.1-0.30.3-0.2-0.20.7-0.20.7
Condit. Reinf. lever reinforcers received0.81.11.6-0.61.01.1-1.10.7-1.3-0.91.11.2-1.21.21.3-0.91.2-0.7
Pavlov. Cond. lever latency0.60.81.90.21.30.8-0.80.6-1.1-0.50.30.8-0.80.90.7-1.40.8-1.3
Pavlov. Cond. magazine entry latency0.50.51.10.1-0.8-0.70.7-0.61.00.7-0.3-0.60.7-0.6-0.61.1-0.61.0
Pavlov. Cond. change in total contacts0.10.20.8-0.9-0.4-0.10.10.10.7-0.10.3-0.10.1-0.1-0.00.7-0.10.6
Pavlov. Cond. index score0.91.22.7-0.1-1.3-1.11.1-0.81.50.7-0.5-1.01.0-1.0-0.91.6-0.91.5
Pavlov. Cond. latency score1.01.22.70.0-1.3-1.11.1-0.91.60.7-0.5-1.01.1-1.0-1.01.6-1.01.6
Pavlov. Cond. lever contacts0.30.51.3-0.3-1.0-0.60.6-0.50.80.3-0.1-0.60.6-0.7-0.51.1-0.61.1
Pavlov. Cond. magazine entry number2.63.25.9-0.92.01.7-1.71.7-2.3-1.41.21.7-1.71.71.6-2.41.6-2.4
Pavlov. Cond. intertrial magazine entries0.60.81.4-0.51.20.9-0.90.9-0.6-0.90.60.9-0.90.90.8-0.90.8-1.2
Pavlov. Cond. lever-magazine prob. diff.0.91.22.8-0.1-1.4-1.11.1-0.91.50.7-0.5-1.01.1-1.0-0.91.7-1.01.6
Pavlov. Cond. response bias0.71.02.4-0.1-1.3-0.90.9-0.81.20.7-0.3-0.90.9-0.9-0.81.6-0.91.5
Conditioned reinforcement - actives0.40.40.80.3-0.6-0.70.7-0.30.90.4-0.5-0.60.6-0.6-0.70.7-0.80.6
Conditioned reinforcement - inactives0.10.10.3-0.0-0.6-0.20.2-0.20.10.3-0.2-0.20.2-0.4-0.20.2-0.50.4
Conditioned locomotion1.01.11.80.4-1.2-1.11.1-0.61.30.7-0.8-1.11.1-1.2-1.01.3-1.31.2
Intermittent access intake day 1-15 change2.12.13.7-1.61.51.3-1.31.8-1.2-0.91.51.4-1.41.41.3-1.81.2-1.9
Intermittent access intake escalation2.32.24.0-1.61.61.3-1.31.8-1.2-0.81.51.5-1.51.41.3-1.91.2-2.0
Intermittent access intake escalation 21.51.53.6-0.91.41.0-1.01.5-1.1-0.81.01.1-1.21.11.0-1.61.0-1.9
Intermitt. access day 1 inactive lever presses0.30.41.6-1.30.40.1-0.10.9-0.70.60.60.1-0.20.30.1-0.70.3-0.9
Intermitt. access day 15 inactive lever presses0.20.20.9-1.00.00.1-0.10.7-0.60.50.50.0-0.00.10.0-0.50.0-0.5
Intermitt. access escalation Index2.21.92.4-1.31.51.4-1.41.4-0.8-1.31.41.5-1.51.51.4-1.31.5-1.5
Intermittent access day 1 total infusions0.20.20.9-0.70.30.4-0.40.30.6-0.90.30.4-0.40.40.40.30.40.2
Intermittent access day 15 total infusions2.22.53.4-1.91.51.6-1.61.7-0.7-1.81.71.7-1.81.61.6-1.31.5-1.3
Intermittent access terminal intake (last 3 days)1.01.12.2-1.51.01.0-1.01.3-0.3-1.41.11.1-1.21.01.0-0.70.9-0.8
Intermittent access total infusions0.80.82.0-1.20.90.9-0.91.0-0.1-1.40.91.0-1.00.90.9-0.40.8-0.5
Intermittent access day 1 locomotion0.40.41.1-1.10.50.6-0.60.80.1-0.80.80.7-0.70.60.6-0.20.5-0.3
Intermittent access day 15 total locomotion1.01.01.30.7-0.9-1.11.1-0.81.10.8-0.9-1.11.0-1.1-1.11.2-1.11.0
Intermittent access total locomotion0.50.50.90.3-0.7-0.80.8-0.50.90.3-0.6-0.70.7-0.8-0.80.9-0.80.8
Intermittent access standard deviation1.41.52.2-1.51.11.2-1.21.5-0.9-0.91.31.3-1.41.11.2-1.21.0-1.4
Cocaine induced anxiety0.00.00.3-0.50.20.1-0.10.2-0.1-0.20.20.1-0.10.20.1-0.30.2-0.0
Post-drug Anxiety0.10.10.50.3-0.1-0.40.4-0.40.70.2-0.4-0.30.3-0.2-0.40.3-0.20.5
Baseline Anxiety0.10.11.10.3-0.1-0.20.2-0.11.1-0.2-0.2-0.10.1-0.1-0.20.4-0.10.1
Lifetime Intake0.30.41.1-0.90.50.6-0.60.60.0-1.10.60.7-0.70.50.6-0.10.5-0.0
Incentive Sensitization - Responses0.30.30.8-0.90.50.4-0.40.8-0.6-0.10.50.4-0.40.30.3-0.50.2-0.6
Incentive Sensitization - Breakpoint0.20.20.6-0.80.40.3-0.30.6-0.5-0.00.40.3-0.40.30.3-0.30.2-0.4
Progressive ratio test 1 active lever presses0.10.10.3-0.50.20.2-0.20.50.0-0.50.10.2-0.20.10.2-0.20.1-0.3
Progressive ratio test 1 breakpoint0.10.10.6-0.80.30.2-0.20.6-0.1-0.60.20.3-0.30.20.2-0.30.1-0.3
Progressive ratio test 1 inactive lever presses3.13.44.9-2.21.71.7-1.72.0-1.7-1.51.81.9-2.01.91.8-1.81.7-1.9
Progressive ratio test 2 active lever presses0.00.00.1-0.40.30.0-0.00.4-0.1-0.10.00.1-0.20.0-0.0-0.1-0.2-0.2
Progressive ratio test 2 breakpoint0.00.00.2-0.40.2-0.00.00.4-0.0-0.20.00.1-0.1-0.0-0.0-0.1-0.2-0.1
Progressive ratio test 2 inactive lever presses0.10.10.3-0.60.2-0.10.10.50.4-0.20.00.0-0.0-0.1-0.10.1-0.2-0.1
Total sessions with >9 infusions0.10.10.3-0.1-0.3-0.30.3-0.20.10.5-0.4-0.30.3-0.5-0.30.4-0.60.5
Short access day 1 total inactive lever presses2.83.14.7-2.11.91.7-1.72.0-1.6-1.21.51.8-1.81.71.7-2.01.6-2.2
Short access day 10 total inactive lever presses0.10.10.3-0.50.10.2-0.20.5-0.40.20.40.3-0.30.30.3-0.40.2-0.6
Short access day 1 total infusions0.30.30.70.4-0.6-0.40.4-0.60.4-0.0-0.7-0.40.5-0.7-0.30.7-0.70.9
Short access day 10 total infusions0.10.20.7-0.2-0.3-0.20.2-0.20.8-0.2-0.1-0.10.1-0.2-0.20.8-0.20.9
Short access total infusions0.10.10.4-0.3-0.10.1-0.1-0.10.3-0.3-0.10.1-0.1-0.00.10.5-0.10.7
Short access day 1 locomotion0.10.10.6-0.80.30.1-0.10.5-0.60.20.10.1-0.1-0.00.2-0.3-0.2-0.2
Short access day 10 total locomotion0.10.10.20.3-0.4-0.30.3-0.30.30.3-0.4-0.30.3-0.3-0.30.2-0.30.4
Short access total locomotion0.10.10.5-0.7-0.2-0.20.20.3-0.00.6-0.1-0.20.2-0.3-0.20.1-0.40.1
Compulsive drug intake4.24.25.8-1.52.02.2-2.21.5-1.7-2.02.12.3-2.42.42.2-1.72.3-1.8
One hour access (0.3 mA shock)0.60.71.2-0.80.90.8-0.80.8-0.1-1.10.71.0-1.00.80.8-0.60.7-0.7
One hour access (shock baseline)0.20.31.0-0.90.40.4-0.40.70.2-1.00.50.4-0.40.20.4-0.30.1-0.3
Number of responses in last shaping day0.10.10.60.30.20.2-0.20.1-0.80.1-0.20.2-0.10.00.2-0.5-0.1-0.4
Context. condit. distance diff. score0.30.40.80.60.60.7-0.7-0.2-0.9-0.00.20.7-0.60.60.7-0.70.6-0.4
Locomotion velocity, session 15.05.37.21.7-2.4-2.42.4-1.92.22.0-2.4-2.52.6-2.7-2.42.2-2.61.9
Locomotion distance, session 11.31.72.80.9-1.5-1.41.4-1.10.71.3-1.4-1.41.5-1.6-1.31.1-1.71.1
Locomotion velocity, session 20.70.81.4-0.6-0.9-1.11.1-0.10.21.2-0.5-1.11.2-1.1-1.10.6-1.00.4
Locomotion distance, session 20.71.01.60.4-1.0-1.21.2-0.60.41.1-1.0-1.21.2-1.3-1.20.7-1.20.5
Locomotion velocity, session 30.10.10.20.2-0.4-0.10.1-0.4-0.10.5-0.1-0.20.2-0.2-0.20.4-0.20.4
Locomotion distance, session 30.10.10.3-0.1-0.10.4-0.4-0.3-0.2-0.10.50.3-0.30.40.30.40.40.5
Stereotopy head waving bouts, day 30.20.30.50.7-0.5-0.50.5-0.60.50.2-0.7-0.50.5-0.5-0.40.5-0.50.6
Stereotopy head waving duration, day 30.30.40.80.8-0.5-0.50.5-0.60.70.3-0.9-0.60.6-0.7-0.50.4-0.70.5
Locomotion velocity, session 70.50.60.9-0.90.70.9-0.90.6-0.5-0.30.90.9-0.90.80.8-0.60.8-0.6
Locomotion distance, session 70.60.71.1-1.00.91.0-1.00.8-0.1-0.51.11.0-1.01.00.9-0.70.9-0.8
Stereotopy head waving bouts, day 71.92.13.21.7-1.7-1.41.4-1.8-0.11.3-1.7-1.41.4-1.6-1.31.2-1.61.4
Stereotopy head waving duration, day 70.40.50.90.9-0.9-0.60.6-1.0-0.70.7-0.9-0.60.6-0.7-0.50.4-0.70.7
Locomotion velocity, session 80.10.10.80.3-0.2-0.00.0-0.4-0.80.9-0.2-0.10.1-0.20.1-0.3-0.1-0.1
Locomotion distance, session 80.10.10.60.8-0.1-0.10.1-0.5-0.40.6-0.5-0.20.2-0.3-0.2-0.1-0.30.0
Degree of sensitization distance0.10.11.00.20.1-0.40.40.11.00.2-0.5-0.30.3-0.3-0.3-0.1-0.3-0.2
Degree of sensitization stereotypy1.51.72.71.6-1.6-1.31.3-1.6-0.51.3-1.5-1.21.2-1.4-1.10.9-1.41.1
Condit. Reinf. active minus inactive responses0.50.50.90.5-1.0-0.60.6-0.60.80.5-0.6-0.70.7-0.8-0.70.9-1.00.9
Condit. Reinf. active-inactive response ratio0.10.10.50.2-0.5-0.10.1-0.30.70.0-0.2-0.20.2-0.4-0.20.6-0.50.6
Condit. Reinf. active responses0.40.50.90.6-0.8-0.60.6-0.61.00.4-0.6-0.70.7-0.8-0.70.9-0.80.8
Condit. Reinf. inactive responses0.50.60.80.9-0.6-0.90.9-0.70.80.6-0.8-0.90.9-0.8-0.90.6-0.70.4
Incentive salience index mean0.40.51.30.4-1.0-0.40.4-0.70.90.4-0.4-0.60.6-0.7-0.61.1-0.81.1
Condit. Reinf. lever presses0.40.51.30.3-0.9-0.50.5-0.81.00.4-0.4-0.60.6-0.6-0.61.1-0.61.2
Time in familiar zone, hab. session 10.40.30.6-0.40.50.7-0.70.6-0.8-0.80.30.6-0.60.40.6-0.60.3-0.8
Time in novel zone, hab. session 10.50.50.80.5-0.8-0.70.7-0.50.80.7-0.6-0.70.7-0.8-0.80.6-0.90.7
Total zone transitions, hab. session 10.10.20.50.3-0.5-0.30.3-0.2-0.20.2-0.5-0.40.4-0.6-0.40.4-0.70.2
Total locomotion distance, hab. session 11.82.63.71.2-1.8-1.61.6-1.41.11.3-1.6-1.81.8-1.8-1.71.7-1.91.7
Locomotion velocity, hab. session 13.14.45.61.8-2.3-2.12.1-1.91.71.6-2.0-2.22.2-2.3-2.12.3-2.32.4
Time in familiar zone, hab. session 20.80.81.4-0.20.91.2-1.20.5-0.6-1.20.61.1-1.11.01.1-0.70.8-0.6
Time in novel zone, hab. session 21.01.01.40.2-1.0-1.21.2-0.60.91.2-0.7-1.21.2-1.1-1.20.9-1.00.8
Total zone transitions, hab. session 20.20.20.40.4-0.5-0.40.4-0.40.30.3-0.5-0.40.4-0.6-0.40.5-0.60.4
Total locomotion distance, hab. session 20.40.61.10.7-0.9-0.70.7-0.80.60.5-0.8-0.70.7-0.8-0.61.1-0.91.0
Locomotion velocity, hab. session 20.60.81.30.8-1.0-0.90.9-1.00.70.6-0.9-0.90.9-1.0-0.81.2-1.01.1
Novel to familiar place preference ratio0.30.31.0-0.3-0.0-0.70.70.31.00.4-0.5-0.70.7-0.6-0.60.0-0.5-0.2
Novelty place preference0.30.31.0-0.40.0-0.60.60.41.00.4-0.4-0.60.6-0.5-0.6-0.0-0.5-0.3
Time in novel zone, NPP test0.30.31.2-0.3-0.0-0.70.70.41.10.4-0.5-0.70.7-0.6-0.70.0-0.5-0.3
Total zone transitions, NPP test0.50.71.80.5-1.0-0.60.6-0.70.90.2-0.6-0.70.7-0.9-0.61.3-0.91.2
Total locomotion distance, NPP test2.94.06.41.4-2.2-1.91.9-1.82.11.3-1.7-2.02.0-2.1-1.92.5-2.12.5
Locomotion velocity, NPP test2.02.95.31.0-2.0-1.61.6-1.61.71.0-1.4-1.71.7-1.7-1.62.3-1.82.3
Pavlov. Cond. lever latency0.10.10.50.10.60.1-0.10.2-0.50.00.00.2-0.20.30.2-0.60.3-0.7
Pavlov. Cond. magazine entry latency0.81.03.0-0.3-1.3-0.70.7-0.61.40.4-0.1-0.90.8-0.8-0.91.7-0.81.7
Pavlov. Cond. change in total contacts0.10.10.6-0.3-0.50.1-0.1-0.20.30.00.3-0.10.0-0.0-0.10.6-0.00.8
Pavlov. Cond. index score0.81.02.50.1-1.3-0.80.8-0.81.10.7-0.4-1.00.9-0.9-1.01.5-0.91.6
Pavlov. Cond. latency score0.40.51.8-0.1-1.0-0.50.5-0.60.80.5-0.2-0.60.6-0.6-0.61.1-0.61.3
Pavlov. Cond. lever contacts0.40.51.50.3-1.0-0.50.5-0.70.70.4-0.3-0.60.6-0.6-0.61.0-0.61.2
Pavlov. Cond. magazine entry number0.20.31.11.10.50.2-0.2-0.2-0.7-0.1-0.50.3-0.30.10.4-0.80.2-0.8
Pavlov. Cond. intertrial magazine entries0.30.40.80.9-0.5-0.50.5-0.60.7-0.1-0.8-0.50.5-0.6-0.40.7-0.70.6
Pavlov. Cond. lever-magazine prob. diff.0.81.02.40.2-1.3-0.80.8-0.81.20.7-0.4-1.01.0-0.9-1.11.5-0.91.6
Pavlov. Cond. response bias0.50.61.9-0.4-1.0-0.50.5-0.31.20.10.0-0.60.6-0.6-0.71.4-0.61.3
Bone: apparent density0.71.11.5-1.01.21.0-1.01.2-1.0-1.00.91.0-1.01.01.0-1.20.9-1.2
Bone surface1.93.45.7-1.91.81.7-1.72.0-2.4-1.41.71.8-1.81.71.8-2.11.6-2.0
Bone volume1.93.24.4-1.61.81.8-1.81.8-2.1-1.61.71.8-1.81.81.8-1.91.7-1.7
Bone: connectivity density2.43.75.7-2.32.11.7-1.72.3-2.2-1.21.81.8-1.81.71.7-2.41.6-2.4
Bone: cortical apparent density2.33.04.02.0-1.6-1.71.7-1.61.81.4-2.0-1.81.8-1.9-1.71.5-1.81.4
Bone: cortical area1.11.62.50.11.01.6-1.60.4-1.4-1.41.11.6-1.61.51.5-0.81.5-0.4
Bone: cortical porosity0.30.40.60.4-0.3-0.80.8-0.10.70.4-0.8-0.70.7-0.7-0.80.1-0.7-0.0
Bone: cortical porosity0.10.10.30.1-0.1-0.40.40.10.50.1-0.4-0.40.4-0.4-0.5-0.0-0.4-0.0
Bone: cortical thickness0.91.45.72.4-1.3-0.60.6-1.90.70.3-1.2-0.80.8-0.8-0.71.4-0.81.9
Bone: cortical thickness2.42.94.62.0-1.9-1.51.5-1.91.71.1-1.7-1.61.6-1.6-1.51.8-1.62.2
Bone: cortical tissue density2.22.83.91.9-1.5-1.71.7-1.51.81.3-2.0-1.81.8-1.9-1.71.5-1.81.3
Bone: elastic displacement0.40.51.7-0.40.90.3-0.30.9-1.0-0.30.10.4-0.40.40.3-1.30.3-1.3
Bone: elastic work0.60.82.2-0.60.90.7-0.70.9-1.5-0.50.50.7-0.70.70.7-1.40.6-1.3
Bone: endosteal estimation3.47.49.7-3.12.72.7-2.72.9-2.3-2.32.82.8-2.82.82.7-2.52.7-2.7
Bone: endosteal perimeter3.47.17.9-2.82.82.7-2.72.7-2.5-2.12.82.8-2.82.82.7-2.52.7-2.6
Bone: final force0.00.00.10.3-0.10.2-0.2-0.2-0.4-0.10.10.2-0.20.20.2-0.10.20.3
Bone: final moment0.10.10.20.10.10.5-0.50.0-0.3-0.30.40.4-0.40.40.4-0.20.40.2
Bone: marrow area3.57.59.5-3.12.82.7-2.72.9-2.4-2.32.82.8-2.92.82.7-2.62.7-2.7
Bone: maximum diameter4.17.59.0-2.02.82.9-2.92.4-2.9-2.52.63.0-3.02.92.9-2.72.8-2.5
Bone: maximum force0.10.20.60.50.30.6-0.6-0.0-0.8-0.50.20.5-0.50.40.5-0.40.4-0.1
Bone: maximum moment0.20.30.60.10.50.8-0.80.2-0.6-0.80.40.7-0.70.70.7-0.50.6-0.2
Bone: minimum diameter7.714.218.1-2.53.74.1-4.13.0-4.3-3.13.64.2-4.24.24.0-3.74.0-3.3
Bone: periosteal estimation2.24.55.7-1.62.12.3-2.31.8-2.0-2.12.12.4-2.42.32.3-1.92.2-1.7
Bone: periosteal perimeter3.05.07.7-1.42.32.4-2.41.8-2.8-1.92.12.5-2.52.42.3-2.22.3-2.0
Bone: post-yield work0.30.40.80.10.50.7-0.70.2-0.4-0.90.50.8-0.80.70.8-0.30.7-0.1
Bone: stiffness0.10.20.60.80.20.5-0.5-0.3-0.4-0.40.20.5-0.50.40.5-0.10.40.2
Bone: tissue strength0.30.30.7-0.70.40.5-0.50.6-0.5-0.80.50.5-0.50.50.5-0.40.4-0.5
Bone: trabecular number0.91.41.9-1.41.21.1-1.11.4-1.1-1.01.11.1-1.11.11.1-1.31.1-1.3
Bone: trabecular spacing0.20.20.70.7-0.6-0.40.4-0.70.40.4-0.2-0.30.3-0.3-0.30.6-0.30.8
Bone: trabecular thickness1.51.83.4-1.51.21.4-1.41.3-1.8-1.01.41.3-1.31.31.3-1.31.2-1.1
Bone: trabecular tissue density0.70.91.3-0.61.11.0-1.00.9-0.5-1.10.71.0-1.01.10.9-1.01.0-1.1
Breakpoint value in progressive ratio session0.40.41.00.4-0.9-0.30.3-0.70.5-0.1-0.7-0.50.5-0.8-0.31.0-0.71.0
Distance traveled before self-admin0.10.10.2-0.5-0.2-0.50.5-0.00.10.4-0.1-0.40.4-0.4-0.40.4-0.30.3
Distance traveled after self-admin0.50.52.6-1.60.70.3-0.31.1-1.0-0.10.90.3-0.40.40.3-0.40.4-0.8
Delta time in closed arm before/after self-admin0.10.10.30.3-0.20.1-0.1-0.5-0.20.10.00.2-0.20.10.10.10.10.5
Delta time in open arm before/after self-admin1.71.62.2-1.41.31.4-1.41.5-0.7-1.31.21.3-1.31.11.4-1.11.1-1.4
Diff in mean of infusions in LGA sessions1.31.52.6-1.61.01.3-1.31.5-0.3-1.41.11.3-1.31.01.4-1.01.0-1.2
Extinction: sum of active levers before priming0.90.91.7-0.90.81.1-1.10.7-1.3-0.90.91.1-1.10.91.1-0.81.0-0.8
Active lever presses in extinction session 60.60.61.6-0.60.90.7-0.70.8-0.2-0.50.40.8-0.80.70.9-1.20.7-1.3
Delta distance traveled before/after self-admin2.42.64.1-1.51.71.6-1.61.7-1.7-1.21.51.6-1.61.71.6-1.71.6-2.0
Delta ambulatory time before/after self-admin3.33.65.2-1.82.01.8-1.82.0-1.8-1.31.91.9-1.92.01.8-2.01.9-2.3
Time in closed arm before self-admin0.10.10.5-0.7-0.0-0.30.30.30.10.3-0.1-0.40.4-0.2-0.40.1-0.2-0.1
Time in closed arm after self-admin1.21.21.61.1-1.0-1.21.2-1.20.71.3-1.1-1.21.1-1.0-1.20.7-1.11.1
Time in open arm before self-admin0.10.10.3-0.30.3-0.10.10.30.10.20.10.0-0.10.1-0.1-0.50.1-0.4
Time in open arm after self-admin1.61.82.2-1.51.31.3-1.31.4-0.9-1.11.41.5-1.51.41.4-1.11.4-1.4
Sum of active levers in priming session hrs 5-60.00.00.2-0.20.10.1-0.10.30.5-0.3-0.00.00.0-0.20.10.00.0-0.3
Time to tail flick, vehicle, before self-admin0.40.40.60.1-0.5-0.70.7-0.40.10.7-0.6-0.70.7-0.8-0.70.7-0.70.4
Time to tail flick, vehicle, after self-admin0.20.20.40.00.60.5-0.50.40.4-0.70.30.4-0.40.50.4-0.20.5-0.4
Time to tail flick, test, before self-admin1.21.24.2-1.30.90.9-0.91.1-2.1-0.41.10.9-1.01.10.8-1.40.8-1.0
Time to tail flick, test, after self-admin0.90.92.2-1.01.00.9-0.91.2-1.0-0.50.80.8-0.70.60.9-1.30.6-1.5
Delta time to tail flick, vehicle, before/after SA0.20.20.50.30.50.6-0.60.30.2-0.70.30.4-0.40.40.5-0.50.5-0.3
Delta time to tail flick, test, before/after SA0.10.11.00.50.0-0.10.1-0.21.00.1-0.3-0.20.2-0.3-0.00.2-0.1-0.1
Ambulatory time before self-admin0.30.30.8-0.0-0.3-0.70.7-0.30.10.9-0.3-0.60.6-0.6-0.70.3-0.60.3
Ambulatory time after self-admin0.50.51.5-1.20.80.3-0.31.1-1.10.20.70.3-0.30.30.3-0.80.3-1.2
Total heroin consumption0.20.31.1-0.6-0.10.7-0.7-0.1-0.0-1.10.20.6-0.50.10.80.50.20.4
Area under the delay curve0.80.91.70.4-1.1-1.01.0-0.60.50.9-1.0-1.01.0-1.2-1.00.7-1.30.8
Delay disc. indifference point, 0s delay0.70.81.8-0.61.10.8-0.80.9-1.4-0.20.60.8-0.80.90.7-1.20.7-1.2
Delay disc. indifference point, 16s delay0.70.71.20.5-1.0-1.11.1-0.70.11.0-0.8-0.80.8-1.0-0.70.6-1.10.8
Delay disc. indifference point, 2s delay0.10.21.0-1.00.10.0-0.00.70.5-0.40.1-0.20.1-0.2-0.30.1-0.3-0.2
Delay disc. indifference point, 24s delay3.93.85.01.7-2.2-2.12.1-1.81.61.6-1.9-2.02.0-2.2-1.81.8-2.22.0
Delay disc. indifference point, 4s delay0.40.51.10.4-0.7-0.60.6-0.50.30.6-0.9-0.80.8-0.9-0.70.5-1.00.6
Delay disc. indifference point, 8s delay2.72.84.60.8-2.0-1.71.7-1.21.21.7-1.7-1.91.9-2.1-1.71.5-2.11.5
Delay discount exponential model param0.91.01.9-0.41.21.0-1.00.6-0.7-0.91.01.1-1.11.31.0-0.81.4-0.9
Delay discount hyperbolic model param0.50.61.3-0.10.90.7-0.70.3-0.6-0.60.80.9-0.91.00.8-0.71.2-0.7
Fecal boli incidents, locomotor time 10.10.10.2-0.1-0.3-0.30.30.20.20.0-0.3-0.20.2-0.5-0.1-0.1-0.3-0.3
Change in fecal boli incidents, locomotor task0.20.20.5-0.2-0.4-0.40.4-0.20.30.7-0.1-0.60.5-0.3-0.60.30.00.4
Time >=10cm from walls, locomotor time 10.90.92.70.3-1.1-0.80.8-0.81.20.4-0.3-1.01.0-0.8-1.01.5-0.61.6
Bouts of movement, locomotor time 12.22.43.51.7-1.4-1.71.7-1.61.91.1-1.5-1.51.5-1.5-1.31.8-1.61.4
Total resting periods, locomotor time 13.43.85.21.9-1.9-2.12.1-1.92.21.3-1.9-1.92.0-1.9-1.82.3-2.11.9
Rest time, locomotor task time 10.80.92.10.7-0.8-1.11.1-0.71.50.3-1.1-0.90.9-1.0-0.81.0-1.10.7
Distance moved, locomotor task time 10.91.01.7-0.70.71.2-1.20.6-0.9-0.81.21.3-1.31.21.1-0.81.1-0.5
Vertical activity count, locomotor time 10.30.30.8-0.50.20.5-0.50.3-0.50.80.90.5-0.50.50.4-0.60.6-0.3
Time >=10cm from walls, locomotor time 20.50.51.00.3-0.8-0.60.6-0.80.70.8-0.4-0.80.7-0.7-0.70.7-0.51.0
Bouts of movement, locomotor time 24.54.96.71.6-2.1-2.32.3-1.82.62.0-2.0-2.52.5-2.4-2.32.2-2.31.8
Total resting periods, locomotor time 25.15.47.41.7-2.2-2.42.4-1.92.71.9-2.2-2.62.6-2.6-2.42.4-2.52.0
Rest time, locomotor task time 21.82.12.61.4-1.5-1.51.5-1.41.11.3-1.6-1.51.5-1.5-1.41.3-1.51.2
Distance moved, locomotor task time 21.11.32.2-0.71.11.4-1.40.6-0.7-1.11.21.5-1.51.41.4-0.81.2-0.5
Vertical activity count, locomotor time 20.30.40.8-0.90.30.6-0.60.5-0.6-0.10.80.8-0.80.50.8-0.50.3-0.5
Weight adjusted by age0.30.30.80.20.90.5-0.50.3-0.9-0.50.10.5-0.50.50.5-0.60.5-0.6
Seeking ratio, delayed vs. immediate footshock0.10.10.5-0.1-0.3-0.30.3-0.2-0.2-0.00.1-0.30.2-0.1-0.30.6-0.00.7
Locomotion in novel chamber1.82.33.7-1.51.91.5-1.51.4-1.2-1.41.31.6-1.61.71.5-1.41.6-1.5
Locomotion in novel chamber post-restriction0.10.10.40.1-0.4-0.20.2-0.40.60.3-0.1-0.30.3-0.3-0.20.7-0.20.6
Progressive ratio0.60.71.5-0.20.90.9-0.90.4-0.5-0.30.80.9-0.91.10.8-0.81.2-0.8
Food seeking constrained by brief footshock0.20.30.90.6-0.6-0.30.3-0.80.40.2-0.4-0.30.3-0.4-0.30.8-0.40.9
Seeking ratio, punishment vs. effort0.91.11.80.5-1.3-1.01.0-0.90.60.5-1.0-1.11.1-1.3-1.01.1-1.31.4
Run reversals in cocaine runway, females0.90.91.40.9-0.8-1.01.0-0.50.71.1-1.1-1.11.2-1.2-1.00.3-1.10.2
Run reversals in cocaine runway, males2.42.33.11.7-1.7-1.41.4-1.81.01.3-1.5-1.51.5-1.5-1.41.6-1.61.7
Latency to leave start box in cocaine runway4.14.55.9-2.22.41.8-1.82.3-2.1-1.72.12.1-2.22.21.9-2.42.0-2.4
Latency to leave start box in cocaine runway, F5.25.78.2-2.62.52.1-2.12.8-2.1-1.92.42.3-2.42.42.2-2.72.2-2.9
Latency to leave start box in cocaine runway, M0.40.41.1-0.70.80.3-0.30.6-1.1-0.40.70.6-0.60.70.4-0.60.6-0.4
Cd content in liver0.40.40.80.1-0.7-0.80.8-0.40.40.9-0.5-0.70.7-0.7-0.70.6-0.80.6
Co content in liver0.40.51.7-1.30.40.6-0.60.8-0.5-0.81.00.7-0.70.60.7-0.20.5-0.4
Cu content in liver5.56.79.81.4-2.7-2.92.9-1.82.12.7-2.4-2.92.9-3.1-2.72.2-3.12.1
Fe content in liver1.01.21.91.0-1.1-1.31.3-0.9-0.41.3-1.2-1.31.3-1.4-1.20.5-1.30.6
K content in liver0.80.82.70.3-0.7-0.90.9-0.61.70.5-0.8-0.90.9-0.9-0.91.1-0.80.8
Mg content in liver0.91.01.40.6-0.8-1.11.1-0.81.20.8-1.2-1.11.1-1.1-1.10.8-1.10.7
Mn content in liver6.77.69.92.4-2.6-3.03.0-2.42.22.6-3.1-3.13.1-3.1-3.02.2-3.02.1
Na content in liver1.51.63.41.9-1.2-1.21.2-1.41.40.5-1.7-1.11.2-1.3-0.91.2-1.31.2
Rb content in liver0.30.30.80.9-0.5-0.50.5-0.6-0.10.6-0.7-0.60.6-0.6-0.60.2-0.60.4
Se content in liver18.822.829.03.7-5.0-5.35.3-4.13.44.5-4.7-5.45.4-5.4-5.14.4-5.24.2
Sr content in liver0.10.10.2-0.5-0.3-0.40.40.1-0.50.50.0-0.30.3-0.3-0.4-0.0-0.30.0
Zn content in liver0.80.91.20.7-1.0-1.01.0-0.80.50.3-1.1-1.01.0-1.1-1.01.1-1.10.8