Hub : Genes

Cpt1a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000014254 0.05 0.03 1.1e-04 0.01 0.02 0.03 0.02 1.1e-02 9.8e-04 8.4e-04 1.8e-03
2 BLA gene expression ENSRNOG00000014254 0.13 0.08 8.9e-05 0.06 0.04 0.06 0.05 2.7e-04 2.6e-03 6.7e-04 8.0e-04
3 BLA mRNA stability ENSRNOG00000014254 0.05 0.04 7.4e-03 0.02 -0 0.04 -0 4.5e-02 4.5e-01 5.4e-03 3.6e-01
4 Brain gene expression ENSRNOG00000014254 0.22 0.09 0.0e+00 0.24 0.23 0.26 0.24 2.0e-22 3.7e-21 6.4e-24 6.3e-22
5 LHb gene expression ENSRNOG00000014254 0.66 0.21 6.0e-04 0.16 0.11 0.08 0.09 1.5e-04 1.3e-03 5.1e-03 3.3e-03
6 Liver mRNA stability ENSRNOG00000014254 0.17 0.08 1.5e-15 0.11 0.1 0.1 0.1 6.3e-12 2.3e-11 2.9e-11 2.4e-11
7 NAcc gene expression ENSRNOG00000014254 0.08 0.06 1.4e-04 0.05 0.05 0.04 0.04 1.5e-04 2.2e-04 2.7e-04 4.1e-04
8 NAcc isoform ratio ENSRNOT00000019652 0.04 0.03 2.1e-03 0.03 0.03 0.02 0.03 1.5e-03 4.8e-03 1.2e-02 4.3e-03
9 NAcc isoform ratio ENSRNOT00000094391 0.06 0.04 2.0e-04 0.05 0.05 0.05 0.04 1.1e-04 1.3e-04 1.9e-04 2.8e-04
10 OFC gene expression ENSRNOG00000014254 0.19 0.12 3.0e-03 0.12 0.05 0.09 0.07 1.1e-03 2.1e-02 3.9e-03 7.9e-03
11 PL gene expression ENSRNOG00000014254 0.08 0.06 2.9e-04 0.03 0.03 0.04 0.03 4.6e-03 2.2e-03 7.0e-04 2.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail1.24.011.1-3.2-1.1-2.6-1.3-0.2-0.2-0.43.3-3.3-0.21.3
BMI without tail0.91.96.2-2.5-1.3-1.3-0.7-0.0-0.2-0.12.2-2.20.00.7
Body weight1.14.69.2-2.61.2-0.31.42.42.32.32.1-2.12.43.0
Epididymis fat weight1.73.99.02.4-1.90.9-1.7-2.1-2.0-2.3-0.90.9-2.3-3.0
Glucose2.43.76.00.2-1.5-1.6-2.4-2.4-2.3-2.41.0-1.0-2.4-2.1
Heart weight0.81.23.20.9-0.40.1-1.1-1.4-1.4-1.4-0.10.1-1.3-1.8
Left kidney weight0.51.44.62.1-0.41.6-0.1-0.5-0.4-0.7-1.51.5-0.4-1.5
Right kidney weight0.61.85.92.40.32.30.60.10.2-0.0-1.81.80.2-1.1
Tail length1.23.56.7-0.11.91.82.32.32.22.6-0.70.72.41.6
Length with tail1.97.012.9-0.93.31.53.13.33.23.6-0.30.33.23.0
Length without tail1.43.05.6-0.82.20.61.92.12.12.20.2-0.22.12.4
Liver weight, left0.10.21.01.0-0.30.5-0.3-0.2-0.4-0.4-0.20.2-0.3-0.6
Liver weight, right0.50.84.81.3-0.22.20.40.50.40.0-0.90.90.5-0.5
Parametrial fat weight1.73.46.41.1-1.9-0.8-2.1-2.2-2.4-2.40.2-0.2-2.3-2.5
Retroperitoneal fat weight2.68.519.93.8-2.70.8-2.5-3.2-3.1-3.3-1.31.3-3.3-4.5
Intraocular pressure0.40.51.50.30.31.20.50.50.50.3-1.11.10.6-0.5
Extensor digitorum longus weight3.012.026.8-2.33.50.73.54.34.44.30.7-0.74.25.2
Soleus weight1.33.79.93.1-0.71.0-0.5-1.5-1.4-1.2-2.72.7-1.5-2.6
Tibialis anterior weight5.819.835.2-1.33.53.05.05.95.95.6-0.80.85.85.8
Tibia length0.92.46.61.51.22.61.51.51.51.4-1.61.61.50.6
Number of licking bursts0.10.20.6-0.6-0.7-0.8-0.3-0.3-0.2-0.3-0.10.1-0.2-0.0
Food consumed during 24 hour testing period0.30.30.80.5-0.90.8-0.0-0.1-0.1-0.2-0.90.9-0.1-0.5
Times rat made contact with spout0.40.41.6-1.3-0.7-0.8-0.5-0.1-0.1-0.30.9-0.9-0.10.2
Mean time between licks in bursts0.60.91.6-1.01.20.11.01.11.01.10.5-0.51.01.2
Mean num. licks in bursts0.10.10.5-0.00.10.2-0.3-0.1-0.2-0.20.7-0.7-0.2-0.2
Std. dev. time between licks in bursts1.72.04.30.12.11.51.61.71.61.4-0.80.81.61.2
Water consumed over 24 hours0.30.31.5-1.2-0.5-0.9-0.10.10.20.30.7-0.70.10.5
Indifference point 0 sec0.10.20.6-0.10.0-0.8-0.3-0.6-0.6-0.30.1-0.1-0.6-0.5
Indifference point AUC1.01.23.6-0.41.90.91.01.31.31.10.1-0.11.41.2
Indifference point function ln k1.42.14.51.9-1.2-0.0-1.0-1.6-1.6-1.5-1.01.0-1.6-2.1
Indifference point function log k1.42.14.51.9-1.2-0.0-1.0-1.6-1.6-1.5-1.01.0-1.6-2.1
Delay discounting total patch changes 0 sec0.10.10.8-0.10.9-0.30.4-0.00.00.4-0.30.30.0-0.1
Delay discounting total patch changes 12 sec1.21.62.8-1.71.7-0.30.91.21.31.40.9-0.91.31.6
Delay discounting total patch changes 18 sec0.20.31.3-0.61.2-0.60.10.10.20.30.6-0.60.20.5
Delay discounting total patch changes 24 sec0.91.12.3-0.81.50.31.21.21.21.5-0.10.11.21.0
Delay discounting total patch changes 6 sec0.50.83.3-1.80.3-1.1-0.30.10.10.21.3-1.30.10.6
Delay discounting time to switch 0 sec1.42.15.0-1.9-1.7-2.2-1.1-0.7-0.6-0.62.0-2.0-0.70.7
Delay discounting water rate 0 sec2.13.48.72.91.12.51.00.20.00.3-2.92.90.2-1.7
Delay discounting water rate 12 sec2.84.111.23.3-0.33.00.4-0.2-0.2-0.3-3.23.2-0.1-2.0
Delay discounting water rate 18 sec0.60.81.81.3-0.31.1-0.3-0.4-0.4-0.5-1.31.3-0.4-1.3
Delay discounting water rate 24 sec1.72.35.82.41.02.31.00.50.40.5-2.32.30.5-0.8
Delay discounting water rate 6 sec1.42.14.92.11.22.01.10.50.50.7-2.22.20.6-0.7
Locomotor activity0.61.04.81.1-0.72.2-0.1-0.1-0.2-0.4-1.11.1-0.0-1.3
Locomotor testing distance0.50.83.21.2-0.61.80.0-0.2-0.2-0.3-1.21.2-0.2-1.0
Locomotor testing rearing0.81.22.70.4-1.70.4-1.3-1.3-1.2-1.50.0-0.0-1.2-1.5
Light reinforcement 10.20.30.70.7-0.20.1-0.2-0.5-0.2-0.4-0.80.8-0.6-0.7
Light reinforcement 21.01.45.22.3-0.60.7-0.6-0.9-0.6-1.0-1.31.3-1.0-1.5
Reaction time number correct0.60.92.60.11.01.60.71.31.20.8-0.30.31.20.4
Reaction time mean minus median0.50.73.5-1.9-0.30.30.00.70.40.10.9-0.90.80.7
Reaction time mean minus median AUC0.60.82.0-1.4-0.01.30.41.20.90.40.4-0.41.20.6
Reaction time num false alarms0.81.11.60.51.21.01.31.11.01.0-1.21.21.00.8
Reaction time num false alarms AUC1.01.42.9-0.11.70.81.51.51.31.4-0.70.71.31.3
Reaction time trials correct on left0.60.92.60.11.01.60.71.31.20.8-0.30.31.20.4
Reaction time trials on left0.81.13.00.11.11.70.91.41.41.0-0.40.41.40.5
Reaction time mean0.40.51.2-1.1-1.1-0.5-0.6-0.7-0.7-0.70.5-0.5-0.6-0.5
Reaction time mean AUC0.50.61.3-0.9-1.1-0.5-0.7-0.8-0.8-0.80.5-0.5-0.7-0.7
Median of all reaction times0.70.91.5-0.9-1.2-1.1-0.8-1.1-1.0-0.90.6-0.6-1.1-0.7
Reaction time omissions0.71.02.0-1.30.70.90.81.41.30.80.3-0.31.41.1
Reaction time false alarm rate0.40.61.20.11.10.11.10.70.60.9-0.70.70.61.0
Reaction time premature initiation rate1.41.85.1-1.11.4-0.11.21.61.61.60.4-0.41.62.3
Reaction time premature initiations2.53.66.4-1.02.01.01.82.52.42.30.0-0.02.52.5
Std. dev. reaction times0.20.31.9-1.4-0.50.0-0.20.3-0.1-0.20.7-0.70.30.2
Reaction time trials completed0.81.13.00.11.11.70.91.41.41.0-0.40.41.40.5
Reaction time trials AUC0.50.82.20.10.91.50.71.21.10.8-0.30.31.20.4
Social response proportion0.50.53.3-1.80.1-0.6-0.30.2-0.1-0.30.8-0.80.20.6
Social responses0.40.51.1-1.10.40.90.61.00.70.4-0.20.20.90.3
Social time0.30.41.2-1.10.50.20.20.70.60.40.6-0.60.60.7
Conditioned locomotion3.44.16.10.02.52.02.42.42.42.2-1.21.22.42.1
Cocaine response after cond. corrected0.10.20.50.7-0.2-0.1-0.3-0.5-0.5-0.4-0.20.2-0.5-0.4
Cocaine response after cond. not corrected0.40.50.90.5-0.9-0.5-0.8-0.8-0.8-0.90.2-0.2-0.8-0.7
Cocaine response before conditioning0.30.41.9-0.7-1.4-0.4-0.7-0.2-0.2-0.50.7-0.7-0.2-0.2
Saline control response1.11.53.5-1.91.3-0.50.81.31.21.30.9-0.91.21.7
Condit. Reinf. active minus inactive responses1.82.24.4-0.5-1.2-0.6-1.9-1.6-1.6-2.11.3-1.3-1.7-1.7
Condit. Reinf. active-inactive response ratio2.02.14.90.4-1.20.2-1.8-1.7-1.6-2.20.5-0.5-1.7-2.2
Condit. Reinf. active responses1.62.23.2-1.3-0.8-1.6-1.8-1.4-1.4-1.71.8-1.8-1.5-1.0
Condit. Reinf. inactive responses0.91.13.8-1.7-0.1-1.9-0.5-0.2-0.2-0.01.5-1.5-0.20.6
Condit. Reinf. lever presses0.60.93.0-1.3-0.9-0.5-0.8-0.2-0.2-0.51.7-1.7-0.30.0
Condit. Reinf. lever reinforcers received1.52.13.7-1.5-0.6-1.7-1.7-1.3-1.2-1.51.9-1.9-1.3-0.7
Pavlov. Cond. lever latency0.20.31.00.10.9-1.00.40.10.10.5-0.70.70.10.4
Pavlov. Cond. magazine entry latency1.41.65.2-2.0-0.1-1.1-0.40.30.30.02.3-2.30.31.0
Pavlov. Cond. change in total contacts0.71.03.0-1.0-0.8-0.7-0.9-0.5-0.5-0.71.7-1.7-0.5-0.3
Pavlov. Cond. index score0.60.73.1-1.0-0.7-0.2-0.5-0.00.0-0.31.8-1.8-0.00.2
Pavlov. Cond. latency score0.50.62.6-0.8-0.7-0.0-0.5-0.0-0.0-0.31.6-1.6-0.10.1
Pavlov. Cond. lever contacts0.20.32.40.3-0.31.60.00.30.3-0.20.2-0.20.3-0.3
Pavlov. Cond. magazine entry number1.61.96.62.30.30.90.5-0.4-0.4-0.1-2.62.6-0.4-1.0
Pavlov. Cond. intertrial magazine entries0.40.61.80.70.2-0.50.1-0.7-0.6-0.1-1.31.3-0.7-0.7
Pavlov. Cond. lever-magazine prob. diff.0.60.83.2-1.2-0.5-0.3-0.40.10.2-0.21.8-1.80.10.4
Pavlov. Cond. response bias0.30.51.7-0.9-0.30.6-0.30.30.2-0.31.3-1.30.20.1
Conditioned reinforcement - actives0.30.30.90.40.80.60.60.20.40.3-0.90.90.2-0.3
Conditioned reinforcement - inactives2.62.96.22.2-1.40.5-1.2-1.7-1.8-1.9-1.41.4-1.9-2.5
Conditioned locomotion3.03.68.92.7-1.41.7-0.5-1.3-1.1-1.4-2.42.4-1.4-3.0
Intermittent access intake day 1-15 change0.90.93.41.80.30.9-0.1-0.5-0.4-0.6-1.31.3-0.5-1.2
Intermittent access intake escalation0.80.82.51.6-0.00.4-0.5-0.9-0.7-0.9-0.90.9-0.9-1.1
Intermittent access intake escalation 20.50.52.41.60.70.8-0.0-0.4-0.2-0.4-0.80.8-0.3-0.6
Intermitt. access day 1 inactive lever presses0.70.81.41.2-0.9-0.2-0.7-0.9-1.0-1.0-0.50.5-1.0-1.0
Intermitt. access day 15 inactive lever presses1.41.62.81.3-1.7-0.5-1.2-1.5-1.4-1.5-0.50.5-1.6-1.4
Intermitt. access escalation Index1.00.92.41.5-0.40.4-0.6-0.9-1.0-0.9-0.70.7-0.8-1.6
Intermittent access day 1 total infusions5.05.79.90.1-2.5-2.3-2.8-2.9-2.8-3.01.1-1.1-3.1-2.3
Intermittent access day 15 total infusions4.55.19.12.0-2.0-0.8-2.3-2.8-2.6-2.9-0.50.5-3.0-3.0
Intermittent access terminal intake (last 3 days)3.84.28.11.7-1.6-1.1-2.2-2.7-2.4-2.7-0.10.1-2.9-2.5
Intermittent access total infusions3.13.46.90.8-1.6-1.6-2.1-2.4-2.1-2.40.3-0.3-2.6-2.0
Intermittent access day 1 locomotion2.93.05.3-0.5-1.6-2.3-2.1-2.0-1.9-2.11.2-1.2-2.2-1.1
Intermittent access day 15 total locomotion2.62.85.81.5-1.3-0.2-1.7-2.1-1.9-2.2-0.50.5-2.2-2.4
Intermittent access total locomotion5.15.810.51.1-2.4-1.5-2.7-3.1-2.9-3.20.4-0.4-3.2-2.8
Intermittent access standard deviation0.30.30.90.9-0.50.1-0.3-0.7-0.3-0.7-0.70.7-0.7-0.5
Cocaine induced anxiety0.10.10.60.2-0.80.4-0.1-0.0-0.4-0.20.0-0.00.0-0.2
Post-drug Anxiety1.01.12.2-0.11.00.81.21.41.31.3-0.20.21.51.4
Baseline Anxiety1.92.04.7-1.02.20.11.41.51.81.60.2-0.21.71.8
Lifetime Intake2.52.85.60.5-1.4-1.6-1.9-2.2-1.9-2.20.4-0.4-2.4-1.7
Incentive Sensitization - Responses0.20.20.40.2-0.70.1-0.3-0.5-0.5-0.5-0.30.3-0.4-0.6
Incentive Sensitization - Breakpoint0.30.30.70.3-0.80.1-0.4-0.6-0.7-0.7-0.40.4-0.6-0.8
Progressive ratio test 1 active lever presses0.50.50.90.8-0.3-0.1-0.3-0.7-0.6-0.7-0.90.9-0.9-1.0
Progressive ratio test 1 breakpoint0.40.41.00.8-0.10.1-0.2-0.5-0.4-0.5-1.01.0-0.7-0.9
Progressive ratio test 1 inactive lever presses0.20.20.40.5-0.4-0.3-0.5-0.6-0.5-0.7-0.30.3-0.6-0.4
Progressive ratio test 2 active lever presses1.31.42.91.2-1.1-0.1-0.9-1.4-1.2-1.3-0.90.9-1.5-1.7
Progressive ratio test 2 breakpoint1.41.63.41.7-0.90.5-0.6-1.2-1.1-1.1-1.41.4-1.3-1.8
Progressive ratio test 2 inactive lever presses4.35.08.72.4-2.2-0.4-2.0-2.7-2.5-2.7-1.11.1-2.8-3.0
Total sessions with >9 infusions0.40.50.90.2-0.3-0.7-0.7-1.0-0.8-0.90.1-0.1-1.0-0.8
Short access day 1 total inactive lever presses1.31.42.70.7-1.5-0.2-1.1-1.4-1.3-1.5-0.60.6-1.5-1.6
Short access day 10 total inactive lever presses1.01.12.11.4-1.40.2-0.8-1.0-1.2-1.1-0.60.6-1.1-1.2
Short access day 1 total infusions1.71.83.70.5-0.9-1.3-1.6-1.9-1.6-1.80.3-0.3-1.8-1.2
Short access day 10 total infusions3.33.78.0-1.0-1.3-2.8-2.2-2.1-1.9-2.11.7-1.7-2.3-1.2
Short access total infusions1.31.43.6-0.4-0.7-1.9-1.3-1.5-1.2-1.40.8-0.8-1.5-0.8
Short access day 1 locomotion1.92.03.2-0.1-1.1-1.3-1.7-1.8-1.6-1.80.7-0.7-1.7-1.8
Short access day 10 total locomotion1.11.21.8-0.7-1.0-1.1-1.3-1.3-1.1-1.30.7-0.7-1.3-1.0
Short access total locomotion0.91.02.2-0.5-0.5-1.5-1.1-1.1-1.0-1.20.8-0.8-1.2-0.8
Compulsive drug intake3.43.36.2-1.31.40.82.02.42.22.3-0.10.12.42.5
One hour access (0.3 mA shock)3.64.18.32.1-2.3-0.1-1.8-2.4-2.1-2.4-0.80.8-2.5-2.9
One hour access (shock baseline)4.35.09.72.6-2.1-0.1-1.9-2.7-2.4-2.7-1.01.0-2.8-3.1
Number of responses in last shaping day0.20.20.70.9-0.00.3-0.1-0.3-0.3-0.3-0.80.8-0.4-0.4
Context. condit. distance diff. score0.70.91.50.8-0.9-1.2-0.9-1.2-1.1-0.90.1-0.1-1.2-0.8
Locomotion velocity, session 10.10.10.6-0.8-0.00.0-0.1-0.10.0-0.30.1-0.1-0.1-0.2
Locomotion distance, session 11.01.32.9-1.2-1.4-1.1-1.2-0.8-0.6-1.01.7-1.7-0.8-0.3
Locomotion velocity, session 21.11.32.2-1.40.80.21.11.31.41.30.7-0.71.31.5
Locomotion distance, session 20.30.51.5-1.0-0.9-0.1-0.40.20.4-0.31.2-1.20.00.3
Locomotion velocity, session 31.51.72.7-1.6-1.4-1.3-1.4-1.1-1.0-1.21.7-1.7-1.1-0.8
Locomotion distance, session 30.10.10.4-0.4-0.3-0.3-0.3-0.3-0.3-0.20.6-0.6-0.3-0.2
Stereotopy head waving bouts, day 31.51.82.8-0.7-1.3-1.7-1.5-1.4-1.3-1.21.4-1.4-1.5-0.9
Stereotopy head waving duration, day 31.21.52.40.0-1.3-1.1-1.5-1.5-1.4-1.40.6-0.6-1.6-1.4
Locomotion velocity, session 70.91.02.7-0.7-0.3-1.6-0.8-1.0-0.9-0.61.2-1.2-1.1-0.3
Locomotion distance, session 70.10.20.4-0.50.3-0.50.10.1-0.00.30.7-0.70.00.5
Stereotopy head waving bouts, day 71.51.72.6-0.4-1.6-1.1-1.6-1.4-1.4-1.51.0-1.0-1.5-1.4
Stereotopy head waving duration, day 71.21.43.3-1.8-0.8-1.6-1.1-0.6-0.6-0.71.7-1.7-0.7-0.1
Locomotion velocity, session 80.91.02.1-1.41.0-0.50.60.90.91.01.2-1.20.91.2
Locomotion distance, session 80.50.71.60.3-1.3-0.5-1.0-0.9-0.8-1.00.7-0.7-1.0-0.9
Degree of sensitization distance0.10.10.4-0.50.2-0.6-0.1-0.1-0.20.10.5-0.5-0.20.3
Degree of sensitization stereotypy0.50.51.0-1.0-0.8-0.7-0.7-0.4-0.5-0.71.0-1.0-0.4-0.3
Condit. Reinf. active minus inactive responses0.30.40.80.1-0.6-0.3-0.9-0.4-0.4-0.80.8-0.8-0.6-0.5
Condit. Reinf. active-inactive response ratio0.40.41.00.7-1.0-0.0-0.8-0.6-0.5-0.80.2-0.2-0.6-0.8
Condit. Reinf. active responses0.10.10.30.4-0.30.2-0.5-0.2-0.1-0.60.4-0.4-0.3-0.4
Condit. Reinf. inactive responses0.00.00.1-0.00.30.30.1-0.00.1-0.00.1-0.10.3-0.0
Incentive salience index mean0.20.30.50.3-0.30.3-0.7-0.3-0.2-0.70.7-0.7-0.4-0.5
Condit. Reinf. lever presses0.20.21.20.80.51.10.10.20.3-0.1-0.00.00.3-0.2
Time in familiar zone, hab. session 11.00.93.10.3-1.8-0.2-1.0-0.9-1.0-0.90.7-0.7-1.0-1.0
Time in novel zone, hab. session 10.30.31.1-0.21.1-0.20.60.40.50.5-0.40.40.40.5
Total zone transitions, hab. session 10.20.31.3-0.2-1.20.6-0.20.30.3-0.10.8-0.80.20.1
Total locomotion distance, hab. session 10.60.92.20.9-1.50.8-0.9-0.9-0.8-1.1-0.30.3-0.9-1.2
Locomotion velocity, hab. session 10.30.41.00.7-1.01.0-0.6-0.4-0.3-0.7-0.50.5-0.5-0.8
Time in familiar zone, hab. session 20.80.91.6-0.40.90.61.11.21.01.2-0.40.41.31.1
Time in novel zone, hab. session 21.01.02.3-0.5-0.8-1.5-1.1-1.1-1.0-1.01.0-1.0-1.2-0.7
Total zone transitions, hab. session 22.63.49.1-2.3-1.8-2.0-1.6-1.0-0.8-1.13.0-3.0-1.0-0.0
Total locomotion distance, hab. session 21.11.52.1-0.7-1.4-1.1-1.5-1.2-1.0-1.41.3-1.3-1.3-0.8
Locomotion velocity, hab. session 21.21.62.6-0.4-1.6-0.8-1.6-1.4-1.2-1.61.1-1.1-1.5-1.1
Novel to familiar place preference ratio0.40.52.0-0.9-0.2-1.4-0.4-0.4-0.2-0.20.9-0.9-0.40.2
Novelty place preference0.50.52.1-0.7-0.4-1.4-0.6-0.7-0.5-0.40.8-0.8-0.6-0.1
Time in novel zone, NPP test0.50.52.1-0.8-0.3-1.5-0.7-0.7-0.5-0.40.9-0.9-0.6-0.1
Total zone transitions, NPP test0.60.83.0-1.7-0.9-0.7-0.6-0.2-0.1-0.31.4-1.4-0.20.2
Total locomotion distance, NPP test0.30.41.0-0.3-1.0-0.3-0.8-0.8-0.6-0.90.2-0.2-0.9-0.7
Locomotion velocity, NPP test0.20.31.0-0.3-1.0-0.0-0.6-0.6-0.5-0.80.1-0.1-0.7-0.6
Pavlov. Cond. lever latency0.10.10.30.0-0.0-0.30.1-0.00.10.0-0.60.60.00.2
Pavlov. Cond. magazine entry latency1.11.42.7-0.7-0.7-1.6-1.3-1.3-1.3-1.01.3-1.3-1.3-0.8
Pavlov. Cond. change in total contacts0.80.91.50.5-0.7-0.3-1.1-1.1-1.2-1.10.8-0.8-1.1-1.2
Pavlov. Cond. index score0.10.20.50.6-0.30.4-0.4-0.4-0.5-0.40.2-0.2-0.4-0.7
Pavlov. Cond. latency score0.20.20.40.3-0.30.0-0.5-0.5-0.6-0.50.4-0.4-0.5-0.6
Pavlov. Cond. lever contacts0.10.10.30.3-0.10.4-0.3-0.2-0.3-0.30.6-0.6-0.2-0.5
Pavlov. Cond. magazine entry number0.00.00.2-0.40.1-0.00.20.20.30.1-0.00.00.20.3
Pavlov. Cond. intertrial magazine entries0.40.51.60.70.10.90.60.40.50.3-1.31.30.50.1
Pavlov. Cond. lever-magazine prob. diff.0.10.20.40.5-0.30.5-0.3-0.3-0.4-0.40.3-0.3-0.3-0.6
Pavlov. Cond. response bias0.10.10.40.5-0.30.3-0.3-0.3-0.4-0.30.2-0.2-0.3-0.6
Bone: apparent density1.62.64.6-1.3-2.1-1.6-1.8-1.4-1.5-1.61.9-1.9-1.4-0.6
Bone surface1.32.36.2-2.2-1.8-1.3-1.3-0.5-0.6-0.82.5-2.5-0.50.3
Bone volume1.22.14.2-1.2-2.0-1.3-1.6-1.1-1.2-1.22.0-2.0-1.1-0.4
Bone: connectivity density1.42.35.4-2.2-1.6-1.6-1.3-0.6-0.7-0.92.3-2.3-0.60.3
Bone: cortical apparent density0.60.82.2-0.21.5-0.40.90.90.91.0-0.10.10.91.4
Bone: cortical area0.60.92.30.80.21.50.91.21.20.9-0.30.31.20.9
Bone: cortical porosity0.20.20.90.1-0.5-0.1-0.4-0.3-0.2-0.40.9-0.9-0.2-0.2
Bone: cortical porosity0.20.20.8-0.2-0.00.00.20.30.40.30.9-0.90.40.5
Bone: cortical thickness3.76.211.10.02.12.52.63.33.32.8-0.70.73.33.0
Bone: cortical thickness1.61.93.2-0.61.21.21.51.71.81.50.1-0.11.81.7
Bone: cortical tissue density0.81.02.6-0.31.6-0.41.01.01.11.1-0.10.11.11.6
Bone: elastic displacement2.32.66.31.71.32.51.61.41.31.3-2.02.01.40.4
Bone: elastic work2.02.64.5-0.41.12.01.82.12.01.9-0.80.82.11.6
Bone: endosteal estimation1.83.98.60.4-2.9-1.0-2.1-2.4-2.5-2.10.7-0.7-2.3-2.4
Bone: endosteal perimeter3.47.112.00.9-2.8-1.6-3.0-3.4-3.5-3.11.0-1.0-3.3-3.3
Bone: final force0.40.71.8-1.30.3-0.40.30.70.80.71.1-1.10.71.2
Bone: final moment0.40.61.2-1.10.2-0.20.20.70.80.61.1-1.10.71.1
Bone: marrow area1.83.98.50.4-2.9-0.9-2.1-2.4-2.5-2.10.7-0.7-2.3-2.4
Bone: maximum diameter0.20.41.31.1-0.91.0-0.1-0.1-0.1-0.2-0.50.5-0.1-0.6
Bone: maximum force0.91.64.3-2.0-1.4-1.3-1.0-0.4-0.3-0.52.1-2.1-0.30.5
Bone: maximum moment0.81.43.9-1.7-1.4-1.0-0.9-0.3-0.3-0.42.0-2.0-0.20.4
Bone: minimum diameter2.24.16.30.3-2.5-1.1-2.4-2.3-2.4-2.41.7-1.7-2.3-2.1
Bone: periosteal estimation0.30.52.50.8-1.60.3-0.6-0.7-0.7-0.60.1-0.1-0.6-0.8
Bone: periosteal perimeter0.40.61.00.2-0.9-0.6-1.0-0.9-1.0-0.90.4-0.4-0.9-0.9
Bone: post-yield work6.58.912.7-1.4-3.5-3.0-3.6-3.2-3.2-3.22.9-2.9-3.1-2.2
Bone: stiffness1.01.63.7-1.6-1.2-1.8-1.1-0.7-0.6-0.71.9-1.9-0.70.2
Bone: tissue strength0.70.72.70.5-1.60.7-1.0-0.6-0.7-1.00.2-0.2-0.6-1.0
Bone: trabecular number1.21.92.6-1.3-1.6-1.5-1.6-1.3-1.3-1.41.5-1.5-1.2-0.5
Bone: trabecular spacing0.40.51.21.01.10.40.90.50.60.9-0.40.40.50.4
Bone: trabecular thickness1.72.14.2-0.4-2.0-0.8-1.7-1.7-1.7-1.70.9-0.9-1.7-1.5
Bone: trabecular tissue density2.12.912.13.50.01.2-0.2-1.1-1.1-0.8-2.32.3-1.1-2.0
Breakpoint value in progressive ratio session0.91.02.8-0.91.2-0.80.61.01.00.90.7-0.70.91.7
Distance traveled before self-admin0.10.10.3-0.5-0.3-0.1-0.3-0.0-0.2-0.20.6-0.6-0.10.1
Distance traveled after self-admin0.20.20.9-0.6-0.90.2-0.4-0.1-0.2-0.30.4-0.4-0.2-0.3
Delta time in closed arm before/after self-admin1.00.91.6-0.40.90.41.21.31.11.1-0.40.41.21.2
Delta time in open arm before/after self-admin0.30.30.70.1-0.8-0.2-0.6-0.5-0.7-0.70.4-0.4-0.6-0.7
Diff in mean of infusions in LGA sessions0.30.30.8-0.40.6-0.20.60.60.60.6-0.30.30.60.9
Extinction: sum of active levers before priming1.01.03.1-1.20.5-0.70.30.80.70.71.2-1.20.91.7
Active lever presses in extinction session 61.81.73.0-0.11.41.31.51.71.61.5-0.50.51.71.2
Delta distance traveled before/after self-admin0.00.00.2-0.3-0.50.3-0.00.1-0.0-0.1-0.10.10.1-0.2
Delta ambulatory time before/after self-admin0.10.10.2-0.5-0.10.40.30.40.40.3-0.20.20.40.0
Time in closed arm before self-admin0.30.41.1-0.7-0.6-1.1-0.6-0.6-0.5-0.60.2-0.2-0.8-0.2
Time in closed arm after self-admin0.30.30.9-0.50.9-0.10.60.60.50.5-0.50.50.40.7
Time in open arm before self-admin0.50.50.70.80.70.80.70.70.60.7-0.50.50.70.9
Time in open arm after self-admin0.10.10.70.8-0.00.60.20.20.20.2-0.10.10.10.2
Sum of active levers in priming session hrs 5-63.23.17.81.31.32.81.91.81.71.7-1.91.91.80.8
Time to tail flick, vehicle, before self-admin1.91.95.3-1.6-0.5-2.3-1.3-0.9-0.9-0.91.9-1.9-1.1-0.2
Time to tail flick, vehicle, after self-admin0.80.92.0-1.40.4-0.60.30.80.70.71.2-1.20.81.4
Time to tail flick, test, before self-admin1.71.62.4-1.0-1.0-1.5-1.6-1.2-1.3-1.31.5-1.5-1.2-0.9
Time to tail flick, test, after self-admin0.10.10.3-0.50.5-0.30.20.30.10.30.1-0.10.30.3
Delta time to tail flick, vehicle, before/after SA0.50.51.1-0.40.30.80.70.90.80.90.2-0.21.10.9
Delta time to tail flick, test, before/after SA3.43.05.00.21.81.12.22.02.02.2-1.41.41.91.7
Ambulatory time before self-admin0.20.20.5-0.3-0.1-0.1-0.6-0.4-0.5-0.50.7-0.7-0.4-0.3
Ambulatory time after self-admin1.41.62.7-0.4-1.6-0.7-1.5-1.4-1.5-1.50.9-0.9-1.4-1.3
Total heroin consumption2.02.45.8-1.51.8-0.61.31.71.71.80.5-0.51.82.4
Area under the delay curve0.91.01.9-0.5-1.0-1.4-1.1-1.0-0.8-0.91.1-1.1-1.2-0.5
Delay disc. indifference point, 0s delay1.71.82.5-1.2-1.4-1.5-1.6-1.3-1.2-1.51.5-1.5-1.2-1.1
Delay disc. indifference point, 16s delay1.01.12.11.0-1.4-0.1-0.9-1.2-1.1-1.1-0.20.2-1.4-1.3
Delay disc. indifference point, 2s delay0.70.81.4-0.1-0.8-0.7-1.0-1.0-1.1-1.00.6-0.6-1.1-1.2
Delay disc. indifference point, 24s delay0.40.30.80.00.20.20.80.60.70.9-0.50.50.60.8
Delay disc. indifference point, 4s delay0.30.30.6-0.5-0.0-0.8-0.6-0.5-0.4-0.60.8-0.8-0.5-0.3
Delay disc. indifference point, 8s delay0.40.41.6-0.5-0.5-1.2-0.4-0.4-0.2-0.20.8-0.8-0.70.3
Delay discount exponential model param0.60.71.40.40.81.20.80.80.70.7-0.90.90.90.4
Delay discount hyperbolic model param0.60.61.30.50.71.10.80.80.70.7-0.90.90.90.4
Fecal boli incidents, locomotor time 10.10.10.20.1-0.5-0.2-0.2-0.1-0.2-0.4-0.10.1-0.1-0.5
Change in fecal boli incidents, locomotor task0.20.20.8-0.90.2-0.7-0.00.10.10.20.6-0.60.10.5
Time >=10cm from walls, locomotor time 13.83.86.7-0.6-2.6-1.9-2.2-2.2-2.2-2.21.3-1.3-2.1-2.0
Bouts of movement, locomotor time 11.21.32.7-0.41.60.11.41.21.31.6-0.40.41.11.6
Total resting periods, locomotor time 10.80.91.9-0.11.40.41.21.01.01.3-0.50.50.81.2
Rest time, locomotor task time 10.90.92.61.6-0.21.50.4-0.30.10.1-1.61.6-0.0-0.3
Distance moved, locomotor task time 10.91.01.9-0.7-0.4-1.4-1.1-0.7-0.8-1.01.3-1.3-0.8-0.6
Vertical activity count, locomotor time 11.11.12.00.6-0.9-0.9-1.2-1.3-1.2-1.40.3-0.3-1.4-1.3
Time >=10cm from walls, locomotor time 20.10.10.20.30.20.30.2-0.10.10.2-0.50.50.0-0.1
Bouts of movement, locomotor time 20.50.51.7-0.10.80.10.60.90.80.80.1-0.10.71.3
Total resting periods, locomotor time 20.20.21.0-0.10.4-0.20.30.50.40.40.2-0.20.21.0
Rest time, locomotor task time 21.92.24.50.5-2.1-0.7-1.7-1.9-1.7-1.90.4-0.4-1.8-1.6
Distance moved, locomotor task time 21.01.22.7-0.21.60.71.31.21.31.4-0.50.51.30.9
Vertical activity count, locomotor time 22.42.63.71.11.71.91.91.61.61.6-1.71.71.70.8
Weight adjusted by age0.70.81.9-0.91.0-0.20.81.01.01.00.4-0.41.01.4
Seeking ratio, delayed vs. immediate footshock0.70.82.8-1.1-0.3-1.7-0.8-0.7-0.6-0.61.2-1.2-0.70.0
Locomotion in novel chamber3.54.39.81.8-2.1-0.5-2.0-2.5-2.5-2.5-0.40.4-2.5-3.1
Locomotion in novel chamber post-restriction1.31.53.51.9-1.10.3-1.0-1.3-1.2-1.4-0.90.9-1.3-1.5
Progressive ratio2.63.07.4-2.7-0.6-2.7-1.2-0.6-0.7-0.62.7-2.7-0.60.4
Food seeking constrained by brief footshock0.20.20.6-0.70.4-0.40.30.40.50.70.4-0.40.40.7
Seeking ratio, punishment vs. effort1.62.05.22.10.52.01.10.60.70.7-2.32.30.6-0.2
Run reversals in cocaine runway, females1.41.44.9-2.2-1.0-1.9-0.7-0.3-0.3-0.31.5-1.5-0.30.8
Run reversals in cocaine runway, males0.90.91.30.21.01.00.91.11.20.6-0.90.91.10.9
Latency to leave start box in cocaine runway0.91.01.8-0.5-1.1-1.0-1.1-1.2-1.3-0.90.9-0.9-1.2-0.7
Latency to leave start box in cocaine runway, F0.60.71.0-0.6-1.0-1.0-0.9-0.9-1.0-0.80.7-0.7-0.9-0.2
Latency to leave start box in cocaine runway, M0.00.00.20.10.00.1-0.1-0.3-0.3-0.00.1-0.1-0.3-0.4
Cd content in liver0.50.61.20.8-0.60.2-0.4-0.7-0.7-0.6-1.11.1-0.6-1.1
Co content in liver0.60.81.71.20.71.10.70.60.60.5-1.31.30.60.1
Cu content in liver0.20.20.50.2-0.00.40.60.50.50.7-0.10.10.50.5
Fe content in liver0.10.10.40.4-0.20.6-0.20.10.2-0.1-0.20.20.1-0.2
K content in liver1.21.23.7-1.2-1.6-0.8-0.7-0.2-0.3-0.41.9-1.9-0.30.3
Mg content in liver3.43.58.2-1.3-2.9-1.6-2.0-1.6-1.7-1.72.3-2.3-1.6-1.0
Mn content in liver0.40.40.8-0.80.20.40.30.80.70.60.9-0.90.70.6
Na content in liver0.30.30.70.4-0.10.90.70.60.60.6-0.40.40.50.2
Rb content in liver2.63.35.4-0.1-2.0-1.8-2.3-2.2-2.2-2.30.9-0.9-2.1-1.7
Se content in liver0.80.91.6-0.3-0.6-1.1-1.1-1.1-1.1-0.90.9-0.9-1.3-1.0
Sr content in liver1.91.73.1-0.41.10.61.51.81.81.6-0.30.31.71.7
Zn content in liver0.40.51.50.1-0.20.50.70.80.80.80.1-0.10.91.2