Hub : Genes

Capn5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000014251 0.36 0.11 0.0e+00 0.28 0.29 0.29 0.29 1.8e-31 3.5e-32 5.8e-33 7.8e-33
2 Adipose mRNA stability ENSRNOG00000014251 0.06 0.04 4.1e-04 0.01 0.01 0.01 0.01 3.5e-02 8.8e-03 9.0e-03 3.7e-02
3 BLA gene expression ENSRNOG00000014251 0.1 0.06 6.0e-05 0.08 0.09 0.11 0.09 6.4e-05 1.2e-05 2.4e-06 1.3e-05
4 BLA mRNA stability ENSRNOG00000014251 0.1 0.07 2.0e-04 0.02 0.07 0.05 0.04 2.1e-02 1.8e-04 9.6e-04 4.6e-03
5 Brain gene expression ENSRNOG00000014251 0.27 0.1 0.0e+00 0.18 0.28 0.27 0.27 1.2e-16 1.3e-25 1.9e-25 2.4e-25
6 Brain mRNA stability ENSRNOG00000014251 0.17 0.08 8.8e-15 0.16 0.18 0.18 0.18 4.7e-15 2.7e-16 4.3e-16 2.1e-16
7 IL gene expression ENSRNOG00000014251 0.54 0.16 5.8e-07 0.1 0.09 0.06 0.09 2.3e-03 3.8e-03 1.5e-02 3.7e-03
8 LHb gene expression ENSRNOG00000014251 0.41 0.14 1.3e-07 0.24 0.2 0.23 0.23 1.8e-06 1.5e-05 4.4e-06 4.2e-06
9 Liver gene expression ENSRNOG00000014251 0.5 0.12 0.0e+00 0.23 0.23 0.23 0.23 6.6e-25 2.8e-25 2.5e-25 2.5e-25
10 NAcc gene expression ENSRNOG00000014251 0.15 0.08 1.8e-07 0.09 0.09 0.07 0.09 2.7e-07 1.6e-07 8.5e-06 2.4e-07
11 NAcc mRNA stability ENSRNOG00000014251 0.11 0.11 2.0e-04 0.05 0.04 0.03 0.04 8.3e-05 5.0e-04 1.9e-03 8.2e-04
12 OFC gene expression ENSRNOG00000014251 0.42 0.17 4.5e-06 0.1 0.16 0.18 0.15 2.0e-03 1.0e-04 5.5e-05 1.8e-04
13 OFC mRNA stability ENSRNOG00000014251 0.19 0.11 2.6e-03 0.03 0.09 0.05 0.07 8.6e-02 4.3e-03 2.1e-02 8.5e-03
14 PL gene expression ENSRNOG00000014251 0.41 0.12 0.0e+00 0.34 0.12 0.35 0.02 6.5e-27 1.6e-09 1.3e-27 1.1e-02
15 PL mRNA stability ENSRNOG00000014251 0.11 0.06 4.5e-08 0.04 0.12 0.1 0.1 3.1e-04 2.5e-09 5.1e-08 1.0e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.31.02.7-1.41.51.0-0.90.8-0.4-0.31.40.2-0.00.0-1.7-1.30.2-1.3
BMI without tail1.73.511.7-3.13.00.9-1.40.9-0.1-1.02.60.0-1.11.2-3.4-1.9-0.7-2.1
Body weight0.73.112.6-3.22.90.6-0.80.50.3-1.42.0-0.5-1.21.0-3.5-1.5-0.8-1.5
Epididymis fat weight1.22.77.3-2.32.71.3-1.41.5-0.7-0.12.7-0.10.2-0.3-2.5-2.10.3-1.9
Glucose0.10.20.5-0.20.3-0.60.7-0.30.3-0.3-0.4-0.6-0.10.1-0.20.5-0.30.7
Heart weight0.81.22.5-0.50.1-1.61.3-1.21.2-0.9-1.2-1.2-1.11.3-0.41.2-1.01.3
Left kidney weight1.02.97.9-2.82.0-1.30.9-1.01.4-1.90.4-1.6-2.01.8-2.80.4-1.90.5
Right kidney weight0.61.75.3-2.21.4-1.00.6-0.81.1-1.50.3-1.2-1.61.2-2.30.2-1.50.2
Tail length2.16.319.5-4.33.4-1.60.6-1.01.8-3.01.3-2.0-3.02.9-4.4-0.1-2.7-0.1
Length with tail0.93.312.1-3.32.6-0.50.0-0.41.1-2.01.3-1.2-2.01.6-3.5-0.6-1.8-0.6
Length without tail0.10.31.20.5-0.50.7-0.30.4-0.40.5-0.10.40.7-1.10.5-0.30.6-0.3
Liver weight, left0.30.51.4-1.01.20.5-0.60.6-0.2-0.10.90.1-0.00.2-1.1-0.90.2-0.9
Liver weight, right1.72.86.5-1.51.71.9-2.11.7-1.20.52.41.10.5-0.8-1.7-2.40.9-2.5
Parametrial fat weight0.40.92.6-0.60.81.1-1.40.9-0.60.11.10.80.1-0.0-0.9-1.40.6-1.6
Retroperitoneal fat weight3.511.528.8-3.24.53.3-3.73.8-2.71.25.41.31.6-1.5-3.4-4.81.9-4.5
Intraocular pressure0.81.23.90.30.0-2.01.6-0.80.7-0.4-1.1-1.3-0.00.70.51.4-0.51.9
Extensor digitorum longus weight0.20.94.4-1.42.1-0.0-0.40.7-0.2-0.41.5-0.80.10.4-1.4-0.90.0-0.5
Soleus weight0.51.44.6-1.82.10.2-0.91.0-0.5-0.21.9-0.10.00.1-1.8-1.40.1-1.2
Tibialis anterior weight0.10.41.0-0.90.6-0.20.1-0.30.6-0.90.2-0.4-0.80.6-1.00.0-0.7-0.0
Tibia length0.92.64.50.2-1.1-1.71.9-2.11.9-1.5-2.1-1.2-1.61.50.22.1-1.61.9
Number of licking bursts3.74.36.30.70.52.5-2.42.5-2.32.12.21.92.2-2.30.6-2.52.3-2.4
Food consumed during 24 hour testing period2.42.95.4-0.0-1.2-1.92.0-2.11.8-1.4-2.1-1.0-1.71.20.22.3-2.02.1
Times rat made contact with spout0.40.51.0-0.50.60.8-0.90.8-0.70.41.00.70.3-0.4-0.4-1.00.3-1.0
Mean time between licks in bursts4.66.410.0-3.01.5-2.82.3-2.42.7-3.0-0.9-2.6-3.12.6-2.91.8-3.21.9
Mean num. licks in bursts2.93.55.2-0.9-0.1-2.32.1-2.12.1-1.9-1.8-1.7-2.12.1-0.82.1-2.22.1
Std. dev. time between licks in bursts1.01.23.5-1.81.0-0.80.3-0.70.9-1.30.3-0.6-1.61.2-1.90.2-1.4-0.0
Water consumed over 24 hours1.31.52.60.8-0.31.5-1.51.3-1.41.41.01.61.3-1.20.8-1.21.3-1.3
Indifference point 0 sec4.67.411.4-1.5-0.2-3.02.8-3.33.3-3.1-2.6-2.5-3.43.2-1.52.8-3.12.6
Indifference point AUC0.10.10.4-0.50.6-0.20.2-0.10.2-0.40.3-0.3-0.20.6-0.5-0.0-0.20.1
Indifference point function ln k1.11.63.80.4-1.3-1.11.3-1.61.5-1.0-1.9-0.6-1.20.90.41.7-1.11.4
Indifference point function log k1.11.63.80.4-1.3-1.11.3-1.61.5-1.0-1.9-0.6-1.20.90.41.7-1.11.4
Delay discounting total patch changes 0 sec3.86.29.1-1.3-0.2-2.72.7-3.03.0-2.8-2.4-2.3-3.02.8-1.32.6-2.82.4
Delay discounting total patch changes 12 sec1.11.53.2-1.51.0-1.21.0-1.01.3-1.4-0.2-1.4-1.51.8-1.50.7-1.40.8
Delay discounting total patch changes 18 sec1.92.44.3-1.61.0-1.81.5-1.41.6-1.9-0.6-1.7-1.82.1-1.51.2-1.81.3
Delay discounting total patch changes 24 sec0.70.91.5-1.20.8-1.00.9-0.81.0-1.2-0.2-1.1-1.10.9-1.20.6-1.20.7
Delay discounting total patch changes 6 sec0.81.32.9-0.1-0.6-1.01.1-1.41.4-1.1-1.3-0.7-1.41.7-0.21.2-1.11.0
Delay discounting time to switch 0 sec4.06.18.61.6-0.52.9-2.82.7-2.82.92.12.52.7-2.81.6-2.52.7-2.6
Delay discounting water rate 0 sec3.35.27.4-1.20.1-2.72.6-2.62.7-2.6-2.2-2.2-2.52.3-1.22.5-2.52.5
Delay discounting water rate 12 sec2.13.14.6-0.5-0.4-2.12.0-2.12.0-2.0-2.0-1.5-1.91.8-0.52.1-1.92.1
Delay discounting water rate 18 sec0.81.01.6-0.90.6-1.21.2-1.01.0-1.1-0.7-1.3-0.90.9-0.81.0-1.11.2
Delay discounting water rate 24 sec0.81.12.50.5-0.7-1.31.4-1.20.9-0.7-1.4-0.8-0.60.60.51.5-0.71.6
Delay discounting water rate 6 sec0.60.91.70.4-0.7-1.31.1-1.11.0-0.7-1.3-0.6-0.80.80.41.3-0.71.3
Locomotor activity0.50.82.6-0.7-0.4-0.80.5-1.11.1-1.1-0.7-0.2-1.61.1-0.90.7-1.30.3
Locomotor testing distance1.93.16.1-2.00.7-1.61.4-1.82.1-2.3-0.7-1.5-2.52.0-2.11.2-2.21.0
Locomotor testing rearing0.91.55.3-2.21.4-0.20.2-0.60.9-1.50.5-0.7-1.61.3-2.3-0.2-1.3-0.3
Light reinforcement 11.32.44.80.40.22.2-1.91.8-1.61.41.71.51.4-1.60.3-1.91.6-2.1
Light reinforcement 20.10.20.80.4-0.90.60.0-0.30.4-0.1-0.60.3-0.3-0.30.30.3-0.1-0.1
Reaction time number correct0.50.73.61.3-1.90.8-0.1-0.50.10.3-1.01.1-0.1-0.71.30.50.00.0
Reaction time mean minus median1.11.52.9-1.20.5-1.40.9-1.21.3-1.5-0.7-1.0-1.71.7-1.30.9-1.40.7
Reaction time mean minus median AUC1.31.73.2-0.7-0.2-1.41.1-1.61.5-1.5-1.2-0.9-1.81.7-0.91.2-1.51.0
Reaction time num false alarms2.12.95.10.11.02.0-1.82.2-1.91.72.31.11.9-1.9-0.0-2.11.7-1.9
Reaction time num false alarms AUC1.21.73.30.20.61.5-1.21.7-1.61.41.60.81.6-1.80.2-1.51.4-1.2
Reaction time trials correct on left0.50.73.61.3-1.90.8-0.1-0.50.10.3-1.01.1-0.1-0.71.30.50.00.0
Reaction time trials on left0.50.73.71.3-1.90.7-0.0-0.50.20.2-1.11.0-0.2-0.71.30.60.00.0
Reaction time mean0.10.10.3-0.30.50.2-0.50.3-0.1-0.10.3-0.00.00.1-0.6-0.50.1-0.5
Reaction time mean AUC0.10.20.4-0.00.30.4-0.60.6-0.40.20.40.20.4-0.3-0.2-0.60.4-0.6
Median of all reaction times0.20.30.50.20.20.6-0.70.7-0.50.40.50.30.6-0.5-0.0-0.70.6-0.7
Reaction time omissions0.10.10.4-0.60.7-0.30.1-0.00.2-0.40.2-0.7-0.2-0.0-0.5-0.1-0.20.0
Reaction time false alarm rate1.31.83.9-0.31.41.1-1.21.8-1.61.22.00.31.7-1.4-0.3-1.71.4-1.2
Reaction time premature initiation rate1.72.36.0-2.51.8-1.10.4-0.81.2-1.70.5-1.2-1.92.3-2.40.0-1.40.0
Reaction time premature initiations0.91.33.6-1.60.6-0.80.5-1.11.3-1.5-0.3-0.7-1.91.8-1.50.5-1.30.2
Std. dev. reaction times0.71.02.7-1.51.2-1.00.4-0.60.8-1.20.1-1.0-1.21.4-1.60.2-1.00.2
Reaction time trials completed0.50.73.71.3-1.90.7-0.0-0.50.20.2-1.11.0-0.2-0.71.30.60.00.0
Reaction time trials AUC0.40.63.01.1-1.70.70.0-0.50.20.1-1.00.9-0.3-0.61.00.6-0.10.0
Social response proportion0.70.71.80.1-0.11.3-1.20.8-0.70.60.81.30.4-0.8-0.1-1.00.5-1.3
Social responses0.91.12.7-0.81.01.0-1.41.2-0.90.61.60.80.5-0.6-0.8-1.50.6-1.6
Social time2.53.36.91.1-0.62.4-2.01.9-1.81.91.32.01.9-2.61.0-1.81.9-2.0
Conditioned locomotion0.10.10.50.6-0.60.10.0-0.0-0.20.3-0.30.50.3-0.20.70.20.20.1
Cocaine response after cond. corrected0.60.71.4-0.21.00.6-0.51.1-0.90.71.0-0.11.2-1.1-0.2-1.01.0-0.6
Cocaine response after cond. not corrected0.10.10.40.20.20.3-0.10.4-0.30.20.1-0.20.7-0.60.1-0.20.6-0.0
Cocaine response before conditioning0.81.03.40.9-1.8-0.40.6-1.31.0-0.6-1.60.2-1.00.70.81.2-0.70.7
Saline control response1.82.44.1-1.50.4-1.41.5-1.71.9-2.0-1.1-1.4-2.01.7-1.61.3-2.01.2
Condit. Reinf. active minus inactive responses6.58.112.0-2.61.2-3.03.0-2.93.3-3.5-1.7-3.3-3.33.1-2.62.4-3.22.6
Condit. Reinf. active-inactive response ratio1.31.32.8-1.20.9-1.21.5-1.01.2-1.4-0.6-1.7-0.90.8-1.11.0-1.11.3
Condit. Reinf. active responses9.413.019.7-3.41.5-3.93.6-3.74.1-4.4-2.1-4.1-4.34.1-3.43.0-4.13.1
Condit. Reinf. inactive responses5.67.012.6-2.50.8-2.82.3-2.83.0-3.3-1.5-2.5-3.63.3-2.62.1-3.31.9
Condit. Reinf. lever presses18.525.535.1-2.60.0-5.85.6-5.85.9-5.8-4.6-5.0-5.75.7-2.75.4-5.55.4
Condit. Reinf. lever reinforcers received10.114.321.3-3.41.4-4.13.9-3.94.4-4.6-2.4-4.3-4.54.3-3.43.3-4.33.3
Pavlov. Cond. lever latency18.525.435.72.4-0.05.8-5.95.8-6.05.74.75.15.5-5.22.4-5.65.4-5.7
Pavlov. Cond. magazine entry latency5.05.79.3-0.3-0.5-2.83.0-2.82.8-2.4-2.7-2.4-2.22.6-0.42.9-2.23.0
Pavlov. Cond. change in total contacts12.617.625.3-2.0-0.1-4.64.9-4.95.0-4.9-4.0-4.2-4.74.3-2.14.6-4.64.6
Pavlov. Cond. index score14.518.926.2-1.9-0.0-5.05.1-5.05.1-4.9-4.2-4.5-4.64.6-1.94.9-4.65.0
Pavlov. Cond. latency score13.116.623.5-1.6-0.3-4.74.8-4.84.8-4.5-4.1-4.2-4.34.2-1.64.7-4.24.7
Pavlov. Cond. lever contacts19.126.637.5-2.5-0.1-5.95.9-6.06.1-5.8-4.8-5.2-5.85.5-2.55.6-5.65.6
Pavlov. Cond. magazine entry number7.79.416.41.1-0.33.8-4.03.3-3.43.23.03.82.6-2.91.0-3.62.9-4.0
Pavlov. Cond. intertrial magazine entries0.60.82.5-1.61.10.4-0.70.3-0.0-0.41.10.3-0.80.5-1.6-0.9-0.5-1.1
Pavlov. Cond. lever-magazine prob. diff.13.717.724.8-1.90.0-4.85.0-4.95.0-4.8-4.0-4.4-4.54.4-2.04.7-4.54.8
Pavlov. Cond. response bias19.226.536.5-2.50.0-6.06.0-5.96.0-5.8-4.8-5.3-5.65.5-2.55.7-5.55.8
Conditioned reinforcement - actives2.02.04.00.2-0.8-1.61.9-1.71.5-1.1-1.9-1.2-1.10.80.32.0-1.32.0
Conditioned reinforcement - inactives0.10.10.30.3-0.20.2-0.20.3-0.40.50.00.30.5-0.50.5-0.10.3-0.1
Conditioned locomotion1.72.04.00.2-0.9-1.71.9-1.71.6-1.2-1.9-1.1-1.10.90.22.0-1.32.0
Intermittent access intake day 1-15 change2.12.13.80.2-0.9-1.91.8-1.81.5-1.1-1.9-1.2-1.31.10.32.0-1.31.9
Intermittent access intake escalation2.82.84.80.1-0.9-2.22.1-2.01.8-1.3-2.1-1.5-1.51.30.12.2-1.52.2
Intermittent access intake escalation 20.70.71.1-0.3-0.3-1.11.0-1.01.0-0.7-0.9-0.8-0.90.8-0.21.0-0.80.9
Intermitt. access day 1 inactive lever presses0.40.50.70.2-0.00.6-0.90.8-0.90.70.70.80.7-0.80.2-0.80.6-0.8
Intermitt. access day 15 inactive lever presses0.10.10.30.2-0.3-0.20.10.0-0.10.3-0.20.00.3-0.60.40.10.10.2
Intermitt. access escalation Index0.00.00.10.3-0.40.1-0.2-0.0-0.00.1-0.10.2-0.10.10.2-0.0-0.0-0.1
Intermittent access day 1 total infusions0.70.81.7-0.70.6-1.31.0-0.80.8-0.9-0.5-1.2-0.70.9-0.60.8-0.91.0
Intermittent access day 15 total infusions2.62.96.2-0.2-0.4-2.52.2-1.91.7-1.4-2.0-1.8-1.41.30.02.2-1.52.4
Intermittent access terminal intake (last 3 days)1.61.74.0-0.5-0.0-2.01.6-1.41.3-1.1-1.3-1.5-1.21.2-0.31.5-1.21.7
Intermittent access total infusions0.80.92.1-0.60.3-1.41.2-0.90.9-0.9-0.8-1.2-0.70.8-0.41.0-0.91.2
Intermittent access day 1 locomotion0.10.10.20.3-0.3-0.20.2-0.1-0.00.1-0.3-0.00.2-0.20.40.30.00.4
Intermittent access day 15 total locomotion1.71.93.2-0.5-0.3-1.81.7-1.61.5-1.3-1.5-1.4-1.31.1-0.41.6-1.51.7
Intermittent access total locomotion0.60.71.3-0.70.2-1.11.0-0.90.9-0.9-0.6-1.0-0.80.8-0.60.9-1.01.0
Intermittent access standard deviation0.10.10.2-0.50.3-0.50.3-0.30.3-0.4-0.1-0.3-0.40.2-0.50.3-0.30.3
Cocaine induced anxiety2.22.63.80.8-0.12.0-1.81.8-1.81.71.51.61.7-1.80.8-1.71.8-1.8
Post-drug Anxiety0.40.40.70.4-0.00.6-0.70.8-0.80.80.50.50.8-0.80.5-0.70.9-0.6
Baseline Anxiety2.62.85.5-0.6-0.1-2.32.0-1.91.7-1.6-1.7-1.7-1.61.8-0.41.9-1.62.1
Lifetime Intake1.01.12.6-0.50.2-1.61.4-1.11.0-1.0-1.0-1.3-0.90.9-0.31.2-1.01.4
Incentive Sensitization - Responses3.53.56.0-1.81.1-2.32.0-1.72.0-2.0-1.0-2.4-1.91.9-1.61.6-2.11.9
Incentive Sensitization - Breakpoint3.33.35.7-1.70.9-2.32.0-1.82.0-1.9-1.1-2.4-1.91.9-1.41.6-2.01.9
Progressive ratio test 1 active lever presses0.20.20.30.5-0.30.3-0.30.4-0.50.50.10.50.5-0.50.5-0.20.5-0.2
Progressive ratio test 1 breakpoint0.20.20.30.5-0.30.4-0.40.4-0.50.60.20.60.5-0.50.5-0.30.5-0.3
Progressive ratio test 1 inactive lever presses0.00.00.2-0.20.1-0.40.2-0.20.2-0.1-0.1-0.2-0.20.2-0.10.2-0.20.2
Progressive ratio test 2 active lever presses2.02.24.1-1.51.0-2.01.7-1.31.5-1.6-0.8-2.0-1.41.3-1.21.3-1.61.6
Progressive ratio test 2 breakpoint1.61.83.3-1.40.9-1.81.5-1.21.4-1.4-0.6-1.8-1.31.3-1.21.1-1.51.4
Progressive ratio test 2 inactive lever presses0.81.02.3-0.90.6-1.51.1-0.90.9-1.0-0.5-1.3-0.90.8-0.70.9-1.11.1
Total sessions with >9 infusions1.71.82.9-0.1-0.6-1.61.6-1.71.4-1.3-1.7-1.0-1.41.5-0.01.7-1.21.6
Short access day 1 total inactive lever presses0.10.10.2-0.10.3-0.30.30.0-0.00.0-0.1-0.40.2-0.3-0.00.2-0.20.4
Short access day 10 total inactive lever presses0.30.30.80.3-0.60.8-0.70.4-0.40.50.20.90.3-0.60.3-0.50.4-0.7
Short access day 1 total infusions2.22.33.6-0.80.0-1.91.7-1.81.7-1.7-1.5-1.6-1.71.7-0.71.7-1.61.7
Short access day 10 total infusions0.60.61.2-0.70.7-1.11.0-0.70.7-0.9-0.4-1.1-0.60.9-0.60.7-0.70.9
Short access total infusions0.50.50.9-0.50.2-1.00.9-0.80.7-0.8-0.6-0.8-0.70.8-0.40.8-0.60.9
Short access day 1 locomotion2.22.35.10.6-1.4-1.71.9-1.91.5-1.0-2.2-1.0-1.10.90.72.1-1.12.1
Short access day 10 total locomotion0.20.20.4-0.50.1-0.60.5-0.50.6-0.6-0.2-0.4-0.60.5-0.50.4-0.60.4
Short access total locomotion0.10.10.50.3-0.7-0.10.2-0.40.3-0.1-0.50.2-0.30.10.30.4-0.10.2
Compulsive drug intake0.00.00.1-0.0-0.2-0.00.1-0.20.2-0.1-0.1-0.1-0.2-0.1-0.10.1-0.20.1
One hour access (0.3 mA shock)2.12.44.5-1.40.8-2.11.8-1.51.6-1.6-1.0-1.9-1.51.6-1.11.4-1.61.7
One hour access (shock baseline)1.41.63.0-0.80.2-1.71.5-1.41.4-1.3-1.1-1.4-1.31.3-0.51.4-1.41.5
Number of responses in last shaping day0.30.31.1-1.01.10.1-0.40.3-0.1-0.20.9-0.1-0.20.4-1.0-0.6-0.1-0.6
Context. condit. distance diff. score1.51.83.7-0.0-0.1-1.91.8-1.41.3-1.0-1.4-1.6-0.91.40.11.6-1.11.9
Locomotion velocity, session 10.30.31.10.9-0.8-0.20.4-0.1-0.20.3-0.6-0.10.5-0.91.00.60.10.6
Locomotion distance, session 10.50.71.60.2-0.8-0.61.1-1.10.9-0.7-1.3-0.7-0.60.10.21.2-0.71.1
Locomotion velocity, session 20.30.30.7-0.50.3-0.80.8-0.50.4-0.5-0.4-0.6-0.30.2-0.30.7-0.70.8
Locomotion distance, session 20.20.30.6-0.3-0.3-0.50.6-0.70.6-0.7-0.6-0.3-0.70.2-0.30.6-0.70.5
Locomotion velocity, session 30.20.20.5-0.1-0.2-0.70.6-0.50.4-0.3-0.6-0.5-0.30.0-0.00.6-0.50.7
Locomotion distance, session 30.70.82.10.4-0.4-1.11.3-0.90.8-0.6-1.2-1.1-0.30.10.41.3-0.51.4
Stereotopy head waving bouts, day 30.60.72.30.0-0.41.0-1.30.6-0.80.50.71.50.1-0.6-0.1-1.00.4-1.4
Stereotopy head waving duration, day 30.20.20.60.3-0.8-0.40.2-0.60.4-0.3-0.70.4-0.60.70.20.5-0.50.2
Locomotion velocity, session 70.20.20.80.20.40.1-0.20.7-0.70.60.4-0.20.9-0.60.3-0.40.6-0.1
Locomotion distance, session 70.20.21.4-0.51.2-0.40.20.4-0.2-0.10.4-0.90.4-0.1-0.5-0.20.20.2
Stereotopy head waving bouts, day 71.01.12.20.3-1.3-0.91.0-1.41.2-0.8-1.5-0.3-1.20.50.31.4-1.21.1
Stereotopy head waving duration, day 71.61.93.2-0.3-0.8-1.51.5-1.81.6-1.4-1.6-0.8-1.71.3-0.31.7-1.71.4
Locomotion velocity, session 81.82.25.90.10.1-2.42.1-1.41.2-1.0-1.6-1.7-0.61.40.31.8-1.02.4
Locomotion distance, session 81.31.93.3-0.3-0.3-1.81.8-1.61.5-1.3-1.5-1.5-1.21.1-0.21.7-1.51.8
Degree of sensitization distance0.70.72.5-1.41.60.2-0.60.6-0.3-0.21.2-0.1-0.10.5-1.4-1.00.0-0.9
Degree of sensitization stereotypy3.03.36.10.2-1.4-1.82.2-2.32.1-1.6-2.4-1.4-1.71.10.32.5-1.82.3
Condit. Reinf. active minus inactive responses0.50.51.9-1.31.4-0.1-0.30.3-0.1-0.40.9-0.4-0.40.6-1.3-0.6-0.2-0.5
Condit. Reinf. active-inactive response ratio0.50.61.7-1.31.1-0.60.0-0.20.4-0.70.4-0.5-0.81.2-1.3-0.3-0.5-0.2
Condit. Reinf. active responses0.30.41.0-0.91.00.4-0.50.5-0.40.11.00.00.0-0.0-0.9-0.80.1-0.8
Condit. Reinf. inactive responses0.10.20.6-0.00.10.6-0.40.5-0.40.50.50.20.4-0.80.1-0.40.3-0.4
Incentive salience index mean0.40.42.0-1.21.4-0.3-0.10.3-0.1-0.30.8-0.6-0.10.4-1.2-0.5-0.2-0.3
Condit. Reinf. lever presses0.10.10.5-0.40.7-0.40.20.2-0.20.10.3-0.50.3-0.1-0.3-0.0-0.10.3
Time in familiar zone, hab. session 10.10.00.10.00.20.1-0.10.3-0.30.30.3-0.10.3-0.10.1-0.20.2-0.1
Time in novel zone, hab. session 10.10.10.3-0.50.60.3-0.40.3-0.2-0.10.60.3-0.00.0-0.6-0.50.1-0.5
Total zone transitions, hab. session 10.40.52.81.3-1.70.10.0-0.60.30.1-1.00.6-0.20.31.10.60.10.1
Total locomotion distance, hab. session 11.72.46.7-0.60.52.2-2.21.5-1.20.82.01.90.4-0.7-0.9-2.11.0-2.6
Locomotion velocity, hab. session 11.21.85.3-0.50.31.9-1.91.2-1.00.71.61.70.3-0.5-0.7-1.80.8-2.3
Time in familiar zone, hab. session 20.70.81.8-1.00.7-1.30.8-0.70.7-0.8-0.1-1.0-0.91.3-0.90.6-1.00.8
Time in novel zone, hab. session 20.10.10.60.2-0.10.50.10.10.0-0.1-0.2-0.10.3-0.80.10.00.20.0
Total zone transitions, hab. session 20.91.23.20.7-1.7-0.41.0-1.51.4-0.9-1.8-0.3-1.20.60.51.4-0.80.9
Total locomotion distance, hab. session 20.70.92.9-0.90.51.5-1.20.6-0.30.01.31.0-0.3-0.3-1.1-1.30.2-1.7
Locomotion velocity, hab. session 20.81.13.4-1.00.51.6-1.30.7-0.40.11.41.0-0.2-0.4-1.2-1.40.3-1.8
Novel to familiar place preference ratio0.20.20.50.1-0.5-0.00.3-0.60.6-0.5-0.7-0.1-0.50.0-0.10.5-0.40.2
Novelty place preference0.10.10.3-0.1-0.3-0.00.4-0.50.5-0.4-0.5-0.2-0.4-0.1-0.20.4-0.30.3
Time in novel zone, NPP test0.20.20.5-0.1-0.2-0.30.6-0.60.7-0.6-0.7-0.5-0.50.1-0.20.6-0.50.5
Total zone transitions, NPP test0.30.41.10.9-1.1-0.20.6-0.60.4-0.0-1.0-0.2-0.0-0.30.80.80.00.7
Total locomotion distance, NPP test1.11.63.7-0.70.71.9-1.51.3-0.90.61.81.00.6-1.4-0.8-1.70.8-1.9
Locomotion velocity, NPP test1.62.25.2-0.60.72.3-1.81.5-1.20.82.01.30.9-1.7-0.8-2.01.1-2.2
Pavlov. Cond. lever latency0.70.92.30.8-0.41.5-1.10.9-0.90.90.71.00.9-0.90.6-0.91.1-1.1
Pavlov. Cond. magazine entry latency2.12.74.0-1.60.8-1.91.6-1.71.9-2.0-1.0-1.7-1.91.7-1.61.3-1.91.4
Pavlov. Cond. change in total contacts0.80.91.4-1.00.6-1.01.2-0.81.0-1.1-0.7-1.2-0.80.5-0.80.9-1.01.1
Pavlov. Cond. index score1.92.44.2-1.71.1-2.01.6-1.41.6-1.8-0.7-1.7-1.71.6-1.61.2-1.81.4
Pavlov. Cond. latency score1.82.34.0-1.60.9-2.01.6-1.41.6-1.7-0.8-1.7-1.71.6-1.51.2-1.71.4
Pavlov. Cond. lever contacts0.60.71.7-1.20.9-1.30.8-0.50.7-0.8-0.2-1.1-0.70.7-1.00.5-1.00.8
Pavlov. Cond. magazine entry number2.43.14.71.5-0.72.2-1.81.8-2.02.11.21.92.0-1.91.5-1.52.0-1.7
Pavlov. Cond. intertrial magazine entries1.51.82.90.40.11.7-1.51.5-1.61.41.31.31.5-1.70.5-1.41.3-1.5
Pavlov. Cond. lever-magazine prob. diff.1.51.93.4-1.50.9-1.81.4-1.21.4-1.5-0.7-1.5-1.41.4-1.31.1-1.61.3
Pavlov. Cond. response bias0.50.61.2-1.10.8-1.10.7-0.50.7-0.8-0.1-0.8-0.80.6-1.00.4-0.90.6
Bone: apparent density0.10.20.40.6-0.1-0.1-0.50.5-0.50.60.20.40.5-0.10.6-0.30.5-0.3
Bone surface1.01.84.6-0.80.7-2.11.5-1.21.4-1.4-0.9-1.6-1.31.6-0.81.3-1.31.5
Bone volume0.50.82.6-0.91.0-1.60.8-0.60.7-0.8-0.1-1.2-0.71.1-0.80.6-0.80.9
Bone: connectivity density0.20.31.01.0-0.6-0.70.3-0.20.00.2-0.70.10.20.51.00.50.10.6
Bone: cortical apparent density0.70.91.50.10.50.8-1.11.2-1.21.01.20.61.1-0.80.1-1.21.0-1.0
Bone: cortical area0.61.02.2-1.41.4-0.80.7-0.50.9-1.10.2-1.2-0.91.2-1.50.2-0.80.4
Bone: cortical porosity0.80.92.40.4-1.4-0.80.8-1.31.1-0.7-1.5-0.1-1.00.60.41.2-0.90.9
Bone: cortical porosity0.60.72.00.5-1.4-0.50.6-1.10.8-0.5-1.40.1-0.90.20.41.1-0.70.7
Bone: cortical thickness0.20.30.6-0.10.50.7-0.60.7-0.50.40.80.30.5-0.2-0.2-0.70.6-0.7
Bone: cortical thickness0.20.31.3-0.30.4-0.50.8-0.40.5-0.5-0.5-1.1-0.10.2-0.30.5-0.20.7
Bone: cortical tissue density0.70.91.50.20.40.9-1.11.2-1.21.11.20.61.1-0.90.2-1.21.0-1.0
Bone: elastic displacement1.21.42.51.1-0.11.0-1.11.4-1.41.50.80.91.6-1.41.1-1.11.5-0.9
Bone: elastic work1.72.24.21.9-0.71.1-1.11.4-1.61.90.51.32.1-1.81.9-0.92.0-0.7
Bone: endosteal estimation1.12.44.5-2.11.7-1.81.3-1.11.4-1.8-0.0-1.9-1.61.6-2.10.8-1.71.1
Bone: endosteal perimeter2.04.16.4-2.11.5-2.52.1-1.82.1-2.3-0.9-2.4-2.12.1-2.01.6-2.31.9
Bone: final force0.10.10.30.20.1-0.50.3-0.20.2-0.2-0.4-0.4-0.00.50.10.20.10.4
Bone: final moment0.10.20.50.00.1-0.70.4-0.40.4-0.3-0.4-0.6-0.30.7-0.00.4-0.10.5
Bone: marrow area0.92.04.0-1.91.6-1.61.1-0.91.3-1.70.0-1.7-1.51.5-2.00.6-1.50.9
Bone: maximum diameter2.13.85.8-1.91.3-2.12.0-1.82.2-2.4-0.9-2.1-2.22.4-2.01.5-2.11.8
Bone: maximum force0.10.20.60.3-0.0-0.80.6-0.40.5-0.3-0.6-0.6-0.20.60.20.6-0.00.7
Bone: maximum moment0.20.40.90.10.0-1.00.8-0.60.6-0.5-0.7-0.8-0.40.80.10.7-0.30.9
Bone: minimum diameter0.71.34.7-2.12.2-0.70.2-0.00.5-1.11.1-1.0-0.90.9-2.1-0.4-0.8-0.1
Bone: periosteal estimation1.42.95.0-2.22.0-1.91.5-1.11.6-2.0-0.1-2.2-1.61.8-2.20.8-1.61.2
Bone: periosteal perimeter1.62.64.0-1.71.2-2.01.5-1.41.6-1.9-0.6-1.7-1.82.0-1.71.1-1.81.3
Bone: post-yield work0.20.31.00.3-0.5-0.70.4-0.70.5-0.4-0.8-0.2-0.61.00.30.6-0.50.5
Bone: stiffness0.00.00.30.4-0.10.1-0.10.1-0.10.2-0.10.20.30.20.2-0.10.5-0.1
Bone: tissue strength1.11.13.51.8-1.90.9-0.60.2-0.51.0-0.61.20.7-0.61.8-0.01.0-0.4
Bone: trabecular number1.01.62.81.4-0.31.0-1.31.5-1.51.70.81.21.7-1.01.4-1.11.6-1.0
Bone: trabecular spacing1.21.62.6-0.4-0.6-1.21.4-1.61.6-1.4-1.4-0.9-1.51.0-0.41.5-1.51.3
Bone: trabecular thickness0.30.41.4-0.61.20.1-0.50.8-0.60.21.0-0.10.5-0.3-0.6-0.80.4-0.6
Bone: trabecular tissue density0.71.02.6-0.70.61.5-1.31.0-0.80.51.40.90.3-0.5-0.8-1.40.6-1.6
Breakpoint value in progressive ratio session0.20.20.60.6-0.10.5-0.10.4-0.50.60.10.30.8-0.60.6-0.20.6-0.0
Distance traveled before self-admin0.30.30.50.20.10.6-0.60.6-0.70.60.50.50.6-0.70.3-0.60.7-0.6
Distance traveled after self-admin1.21.42.21.4-1.21.4-1.10.8-1.11.30.21.51.1-1.41.4-0.71.3-1.0
Delta time in closed arm before/after self-admin0.70.73.1-1.01.80.1-0.50.9-0.60.21.4-0.40.50.2-0.9-1.00.2-0.6
Delta time in open arm before/after self-admin2.12.02.9-1.00.3-1.61.5-1.61.7-1.6-1.1-1.5-1.71.5-1.01.4-1.71.4
Diff in mean of infusions in LGA sessions3.33.77.10.80.32.7-2.22.3-2.22.02.01.82.1-2.00.6-2.22.0-2.2
Extinction: sum of active levers before priming0.20.20.8-0.60.9-0.30.10.20.0-0.20.5-0.50.1-0.2-0.6-0.2-0.30.1
Active lever presses in extinction session 62.82.76.70.4-1.8-1.41.8-2.21.9-1.3-2.6-0.7-1.70.80.42.2-1.61.8
Delta distance traveled before/after self-admin0.20.21.40.7-1.20.2-0.1-0.30.10.1-0.70.6-0.2-0.00.70.30.1-0.0
Delta ambulatory time before/after self-admin0.40.42.31.1-1.50.10.0-0.40.10.3-0.90.6-0.0-0.11.10.50.20.2
Time in closed arm before self-admin1.01.13.21.0-1.7-0.81.0-1.30.9-0.5-1.8-0.1-0.70.40.91.5-0.61.2
Time in closed arm after self-admin0.50.62.01.4-0.80.1-0.10.4-0.60.9-0.40.51.1-0.71.40.10.70.3
Time in open arm before self-admin2.62.84.10.40.52.0-1.92.0-2.01.81.81.41.8-1.60.4-2.01.9-1.9
Time in open arm after self-admin0.40.41.5-1.21.0-0.1-0.1-0.10.3-0.60.6-0.4-0.70.6-1.2-0.3-0.5-0.3
Sum of active levers in priming session hrs 5-60.00.00.1-0.2-0.00.2-0.1-0.00.1-0.10.00.1-0.2-0.4-0.3-0.1-0.2-0.2
Time to tail flick, vehicle, before self-admin0.60.61.2-0.00.50.8-1.00.9-0.80.71.10.70.7-0.20.1-1.00.9-1.0
Time to tail flick, vehicle, after self-admin1.41.52.60.1-0.6-1.51.5-1.51.3-1.1-1.6-0.9-1.11.3-0.11.6-1.11.6
Time to tail flick, test, before self-admin0.20.20.8-0.50.9-0.20.4-0.00.2-0.40.2-0.7-0.10.4-0.60.1-0.40.3
Time to tail flick, test, after self-admin0.60.71.5-1.21.2-0.80.7-0.40.6-0.90.1-1.2-0.50.4-1.20.3-0.90.6
Delta time to tail flick, vehicle, before/after SA2.92.85.90.4-1.2-2.02.1-2.01.7-1.3-2.4-1.2-1.41.20.32.3-1.42.2
Delta time to tail flick, test, before/after SA0.10.10.40.2-0.50.1-0.20.0-0.10.1-0.10.30.1-0.60.3-0.00.1-0.2
Ambulatory time before self-admin0.40.41.10.6-0.10.5-0.40.7-0.70.80.40.40.9-1.00.6-0.40.8-0.3
Ambulatory time after self-admin1.11.32.91.6-1.51.1-0.70.6-0.91.3-0.21.31.1-1.41.7-0.31.1-0.5
Total heroin consumption0.00.10.20.2-0.3-0.10.3-0.30.2-0.1-0.40.0-0.00.00.20.3-0.10.3
Area under the delay curve0.10.10.50.20.0-0.30.6-0.30.2-0.2-0.4-0.50.10.00.20.5-0.20.7
Delay disc. indifference point, 0s delay0.70.71.2-0.80.3-0.70.9-0.91.0-1.1-0.6-1.0-1.00.7-0.80.8-1.10.8
Delay disc. indifference point, 16s delay0.20.20.70.8-0.5-0.30.3-0.0-0.20.3-0.60.00.5-0.50.80.40.20.5
Delay disc. indifference point, 2s delay1.21.32.0-0.5-0.2-1.11.4-1.41.4-1.2-1.2-1.2-1.20.9-0.41.4-1.31.4
Delay disc. indifference point, 24s delay0.80.81.70.70.20.8-0.71.0-1.21.00.70.61.3-1.10.7-0.81.1-0.5
Delay disc. indifference point, 4s delay1.11.12.4-1.20.9-0.91.2-0.81.1-1.3-0.4-1.6-0.90.5-1.10.8-1.31.1
Delay disc. indifference point, 8s delay0.30.30.90.3-0.1-0.60.8-0.50.4-0.3-0.7-0.6-0.20.50.30.8-0.31.0
Delay discount exponential model param0.10.10.5-0.30.10.3-0.60.3-0.20.10.50.5-0.10.1-0.3-0.50.2-0.7
Delay discount hyperbolic model param0.20.30.80.0-0.10.5-0.80.5-0.40.40.60.80.2-0.20.0-0.70.5-0.9
Fecal boli incidents, locomotor time 11.11.22.80.1-0.3-1.71.5-1.21.1-0.7-1.2-1.1-0.70.90.21.4-0.91.7
Change in fecal boli incidents, locomotor task1.31.32.10.9-0.61.4-1.41.1-1.31.10.51.51.0-1.10.8-1.11.3-1.3
Time >=10cm from walls, locomotor time 11.51.53.20.4-1.0-1.31.4-1.51.2-0.9-1.8-0.8-1.11.00.31.7-1.11.5
Bouts of movement, locomotor time 10.20.20.6-0.20.1-0.80.7-0.50.4-0.5-0.4-0.7-0.30.0-0.20.6-0.40.7
Total resting periods, locomotor time 10.10.10.40.4-0.3-0.50.5-0.30.1-0.1-0.5-0.30.2-0.30.30.5-0.00.6
Rest time, locomotor task time 10.30.31.80.9-0.60.00.30.1-0.30.3-0.60.00.7-1.40.80.30.40.4
Distance moved, locomotor task time 10.80.92.6-1.61.4-0.40.2-0.20.6-0.80.8-0.9-0.91.5-1.6-0.1-0.90.0
Vertical activity count, locomotor time 10.70.72.7-1.10.9-0.50.4-0.50.8-0.80.4-0.7-1.01.7-1.20.1-0.80.2
Time >=10cm from walls, locomotor time 21.01.11.7-0.80.3-1.01.2-1.11.1-1.3-0.9-1.3-1.10.8-0.81.0-1.31.1
Bouts of movement, locomotor time 20.70.71.3-0.80.1-1.10.8-0.90.9-1.1-0.7-0.8-1.10.6-0.80.8-1.10.7
Total resting periods, locomotor time 20.40.40.9-0.50.0-1.00.6-0.70.7-0.8-0.6-0.6-0.80.3-0.50.6-0.80.5
Rest time, locomotor task time 22.02.33.31.5-0.51.5-1.71.6-1.71.71.11.71.7-1.81.3-1.41.7-1.5
Distance moved, locomotor task time 23.13.65.6-2.21.2-1.62.0-1.82.1-2.2-0.8-2.4-2.12.0-2.01.5-2.31.6
Vertical activity count, locomotor time 21.71.93.7-1.91.5-1.11.1-0.91.3-1.50.0-1.7-1.51.9-1.90.6-1.40.9
Weight adjusted by age1.01.13.6-1.91.8-0.60.4-0.20.6-1.10.8-1.2-0.81.0-1.9-0.1-1.00.1
Seeking ratio, delayed vs. immediate footshock1.51.73.40.60.41.1-1.21.7-1.71.51.30.81.8-1.80.7-1.31.7-1.0
Locomotion in novel chamber0.91.12.40.3-0.8-1.31.2-1.31.2-0.9-1.5-0.7-1.00.80.11.5-0.91.4
Locomotion in novel chamber post-restriction3.44.08.70.4-1.3-2.42.5-2.42.2-1.6-3.0-1.5-1.61.40.32.7-1.62.7
Progressive ratio0.10.20.50.6-0.4-0.20.6-0.20.10.2-0.5-0.20.3-0.00.60.50.20.7
Food seeking constrained by brief footshock1.82.24.5-1.40.3-1.51.2-1.71.8-1.9-1.0-1.4-2.11.6-1.41.2-1.80.9
Seeking ratio, punishment vs. effort1.11.43.4-1.70.6-0.90.4-1.01.2-1.6-0.2-0.8-1.81.4-1.60.4-1.50.0
Run reversals in cocaine runway, females1.71.77.1-2.12.70.2-0.71.1-0.5-0.12.1-0.60.20.6-1.9-1.4-0.0-1.0
Run reversals in cocaine runway, males0.20.20.80.5-0.0-0.60.6-0.10.00.1-0.5-0.40.4-0.10.60.50.00.9
Latency to leave start box in cocaine runway1.81.93.80.6-0.21.9-1.61.5-1.51.41.21.51.4-1.70.7-1.51.5-1.6
Latency to leave start box in cocaine runway, F1.21.32.3-0.10.41.5-1.31.3-1.21.11.41.01.0-1.40.0-1.41.1-1.4
Latency to leave start box in cocaine runway, M0.80.71.61.3-1.21.0-0.70.4-0.70.9-0.21.20.7-0.71.2-0.30.9-0.5
Cd content in liver1.01.12.5-0.31.01.1-1.11.3-1.10.81.60.61.0-0.7-0.3-1.41.0-1.2
Co content in liver0.91.12.5-1.51.6-1.10.8-0.40.7-1.00.3-1.4-0.71.0-1.50.3-1.10.7
Cu content in liver0.91.03.2-1.81.2-0.70.7-0.60.8-1.2-0.1-0.9-1.10.9-1.70.3-1.20.4
Fe content in liver0.10.10.5-0.40.7-0.30.30.10.1-0.20.1-0.60.10.1-0.30.00.00.3
K content in liver0.30.31.00.1-0.10.6-0.80.6-0.70.60.61.00.4-0.30.1-0.70.4-0.8
Mg content in liver0.10.10.3-0.3-0.1-0.40.3-0.40.4-0.4-0.3-0.2-0.50.2-0.20.4-0.50.3
Mn content in liver1.51.73.01.6-1.21.4-1.01.1-1.31.60.21.51.5-1.71.6-0.71.4-0.9
Na content in liver0.60.72.60.8-1.6-0.40.5-1.00.6-0.2-1.50.3-0.70.30.81.0-0.50.6
Rb content in liver0.60.81.3-1.10.8-1.10.8-0.60.8-1.0-0.4-1.1-0.81.1-1.00.5-1.00.7
Se content in liver3.94.77.51.6-0.72.6-2.22.3-2.52.51.42.42.5-2.71.6-2.02.4-2.0
Sr content in liver0.10.10.20.3-0.0-0.40.4-0.00.00.1-0.3-0.20.3-0.30.30.30.10.5
Zn content in liver4.14.57.2-1.50.2-2.32.2-2.52.5-2.5-1.7-2.0-2.72.4-1.62.1-2.52.0