Igf1r

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000014187 0.03 0.02 4.1e-03 0.02 0.02 0.01 0.02 9.7e-04 6.3e-03 1.2e-02 4.1e-03
2 Adipose mRNA stability ENSRNOG00000014187 0.05 0.03 6.8e-05 0.04 0.04 0.04 0.04 8.1e-06 7.8e-05 9.1e-05 9.5e-06
3 BLA gene expression ENSRNOG00000014187 0.63 0.12 0.0e+00 0.31 0.3 0.33 0.34 2.6e-17 2.8e-16 2.5e-18 1.4e-18
4 Brain gene expression ENSRNOG00000014187 0.32 0.1 0.0e+00 0.28 0.3 0.32 0.31 4.5e-26 1.2e-27 1.6e-30 1.7e-29
5 Brain mRNA stability ENSRNOG00000014187 0.63 0.09 0.0e+00 0.56 0.5 0.57 0.57 1.9e-62 2.6e-53 1.1e-64 7.1e-64
6 Eye gene expression ENSRNOG00000014187 0.4 0.17 6.1e-03 0.16 0.1 0.11 0.14 2.2e-03 1.3e-02 1.1e-02 4.1e-03
7 IL gene expression ENSRNOG00000014187 0.19 0.11 5.4e-03 0.07 -0.01 -0.01 0.02 9.4e-03 5.1e-01 6.1e-01 1.2e-01
8 LHb gene expression ENSRNOG00000014187 0.18 0.1 4.4e-03 -0.01 0.04 0 -0 7.8e-01 5.1e-02 2.6e-01 4.5e-01
9 NAcc gene expression ENSRNOG00000014187 0.14 0.07 7.3e-10 0.08 0.09 0.13 0.1 1.5e-06 4.5e-07 5.4e-10 5.2e-08
10 OFC gene expression ENSRNOG00000014187 0.36 0.15 6.9e-05 0.08 0.13 0.13 0.12 5.6e-03 6.2e-04 6.0e-04 7.6e-04
11 PL gene expression ENSRNOG00000014187 0.33 0.12 2.9e-14 0.15 0.18 0.18 0.16 9.6e-12 1.1e-13 1.9e-13 1.7e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail1.03.110.10.0-3.2-1.6-2.1-1.4-1.8-2.00.2-2.3-1.3-1.1
BMI without tail1.22.56.40.0-2.5-1.4-1.8-1.3-1.7-1.9-0.1-2.0-1.4-1.1
Body weight2.08.326.20.3-5.1-2.4-3.4-1.7-3.2-3.8-0.3-3.5-2.2-1.7
Epididymis fat weight0.30.73.40.9-1.8-0.1-0.5-0.1-0.3-0.11.5-0.60.50.5
Glucose1.32.03.2-0.3-1.7-1.5-1.6-1.3-1.8-1.0-1.11.3-1.3-1.8
Heart weight0.00.00.2-0.1-0.3-0.1-0.1-0.1-0.40.00.4-0.10.20.1
Left kidney weight0.30.92.2-1.2-0.30.60.90.41.01.01.5-0.41.01.5
Right kidney weight0.41.03.4-1.2-0.50.20.7-0.30.91.41.80.41.01.2
Tail length0.82.66.10.1-2.3-1.3-1.9-0.9-1.9-2.5-0.9-1.5-1.6-1.3
Length with tail1.24.513.50.7-3.7-1.4-2.4-0.5-2.6-3.4-0.6-2.4-1.6-1.1
Length without tail1.22.77.60.0-2.8-1.3-1.9-0.7-2.0-2.3-0.6-1.8-1.3-1.1
Liver weight, left0.40.62.8-1.7-1.0-0.8-0.6-0.7-0.1-0.5-0.3-1.1-0.5-0.2
Liver weight, right0.30.52.00.1-1.4-0.0-0.50.4-1.1-1.1-0.4-0.1-0.30.1
Parametrial fat weight1.22.38.30.2-2.6-1.0-1.5-0.5-1.2-2.10.3-2.9-1.0-0.4
Retroperitoneal fat weight0.61.96.32.5-1.11.00.31.30.40.12.3-0.81.51.5
Intraocular pressure0.10.20.50.7-0.5-0.3-0.2-0.40.10.20.70.10.3-0.1
Extensor digitorum longus weight0.31.45.60.0-2.4-0.4-0.9-0.4-0.9-1.30.9-2.2-0.30.2
Soleus weight0.10.41.10.6-1.00.3-0.10.3-0.4-0.60.8-1.10.30.6
Tibialis anterior weight0.62.04.42.0-0.21.61.11.60.60.72.10.91.71.8
Tibia length3.710.416.3-1.0-3.5-3.3-3.9-2.6-4.0-4.0-2.6-2.2-3.5-3.4
Number of licking bursts0.60.71.8-1.3-0.6-0.9-0.6-1.3-0.5-0.3-0.6-0.3-0.9-1.0
Food consumed during 24 hour testing period0.40.52.81.7-0.10.50.20.9-0.10.00.50.70.60.4
Times rat made contact with spout0.20.20.6-0.80.00.10.5-0.30.50.70.80.20.30.4
Mean time between licks in bursts2.73.89.4-0.52.41.92.31.81.72.20.23.11.71.8
Mean num. licks in bursts0.60.71.30.50.70.80.91.00.80.80.80.41.01.2
Std. dev. time between licks in bursts0.50.63.3-0.90.70.30.6-0.10.41.0-0.01.80.30.2
Water consumed over 24 hours0.30.41.00.90.10.60.50.40.30.51.00.60.70.6
Indifference point 0 sec1.72.73.8-0.7-1.6-1.9-1.8-1.5-1.9-1.9-1.4-1.1-1.8-1.8
Indifference point AUC4.04.77.8-1.3-2.8-2.0-2.4-1.8-2.3-2.6-1.5-2.5-2.4-1.9
Indifference point function ln k0.50.81.50.61.20.60.80.31.21.20.90.80.90.5
Indifference point function log k0.50.81.50.61.20.60.80.31.21.20.90.80.90.5
Delay discounting total patch changes 0 sec1.62.53.9-0.7-1.5-1.8-1.8-1.4-1.9-2.0-1.4-1.0-1.7-1.8
Delay discounting total patch changes 12 sec1.62.14.9-0.3-1.7-1.3-1.7-0.7-2.2-1.9-1.5-0.6-1.5-1.4
Delay discounting total patch changes 18 sec0.40.50.7-0.7-0.8-0.6-0.6-0.7-0.8-0.8-0.4-0.7-0.8-0.6
Delay discounting total patch changes 24 sec0.50.61.80.8-1.2-0.3-0.8-0.0-1.3-1.2-0.2-0.7-0.6-0.3
Delay discounting total patch changes 6 sec2.94.47.7-0.1-2.5-1.9-2.5-1.5-2.6-2.8-1.5-1.9-2.3-2.0
Delay discounting time to switch 0 sec3.24.96.51.92.52.52.52.61.92.11.51.92.42.4
Delay discounting water rate 0 sec0.40.61.0-0.1-0.9-0.8-1.0-0.7-0.6-0.9-0.5-0.9-0.8-0.9
Delay discounting water rate 12 sec0.50.81.7-0.3-0.5-1.0-1.0-1.0-0.7-0.9-0.9-0.5-1.1-1.3
Delay discounting water rate 18 sec0.30.42.30.8-0.20.20.1-0.30.50.61.50.10.70.3
Delay discounting water rate 24 sec0.20.21.40.5-0.20.10.1-0.20.40.51.20.20.50.2
Delay discounting water rate 6 sec0.20.41.41.20.30.70.40.50.30.40.80.20.60.5
Locomotor activity0.40.71.51.21.00.90.61.10.20.4-0.11.20.50.6
Locomotor testing distance0.60.92.21.51.21.20.91.20.60.60.40.90.80.8
Locomotor testing rearing0.40.62.30.51.50.40.60.30.30.8-0.21.50.3-0.1
Light reinforcement 10.61.22.2-1.0-1.0-0.9-1.0-0.8-1.2-1.5-1.4-0.2-1.3-1.0
Light reinforcement 20.40.53.0-1.7-0.8-0.1-0.0-0.30.0-0.20.0-1.0-0.30.4
Reaction time number correct2.53.68.4-1.3-2.9-2.0-2.2-2.3-1.8-1.8-0.4-1.5-1.9-1.7
Reaction time mean minus median0.30.41.80.50.10.70.41.3-0.1-0.6-0.6-0.20.30.7
Reaction time mean minus median AUC0.10.10.4-0.1-0.40.2-0.10.6-0.4-0.6-0.6-0.1-0.10.3
Reaction time num false alarms3.64.97.41.91.72.72.42.72.01.92.11.42.52.7
Reaction time num false alarms AUC3.44.87.71.71.62.62.42.62.11.92.11.22.52.8
Reaction time trials correct on left2.53.68.4-1.3-2.9-2.0-2.2-2.3-1.8-1.8-0.4-1.5-1.9-1.7
Reaction time trials on left2.43.47.9-1.3-2.8-2.0-2.2-2.2-1.8-1.8-0.4-1.4-1.9-1.7
Reaction time mean1.01.42.50.31.41.41.61.31.21.40.50.81.31.4
Reaction time mean AUC0.91.22.3-0.21.31.01.40.81.31.50.50.71.11.2
Median of all reaction times1.31.83.8-0.11.61.31.80.91.51.90.71.11.41.3
Reaction time omissions0.71.03.4-1.21.40.61.00.10.81.2-0.51.80.30.4
Reaction time false alarm rate6.18.712.42.32.93.43.43.52.92.62.31.63.33.5
Reaction time premature initiation rate0.30.41.51.20.90.50.40.80.20.00.10.60.40.2
Reaction time premature initiations0.20.30.70.3-0.5-0.5-0.7-0.4-0.7-0.9-0.30.0-0.6-0.7
Std. dev. reaction times0.60.82.00.61.01.11.11.40.70.40.00.10.91.1
Reaction time trials completed2.43.47.9-1.3-2.8-2.0-2.2-2.2-1.8-1.8-0.4-1.4-1.9-1.7
Reaction time trials AUC2.13.07.1-1.2-2.7-1.8-2.1-2.1-1.6-1.6-0.3-1.4-1.7-1.5
Social response proportion0.50.50.90.30.70.40.50.50.90.61.0-0.60.90.9
Social responses0.50.61.40.9-0.4-0.7-1.1-0.0-0.8-1.2-0.7-0.5-0.7-0.8
Social time0.30.41.3-0.40.0-0.7-0.6-0.2-0.6-0.8-1.1-0.1-0.7-0.8
Conditioned locomotion1.01.23.1-1.8-0.2-1.2-0.9-1.2-0.7-0.7-1.60.0-1.2-1.4
Cocaine response after cond. corrected0.50.52.1-0.1-0.2-0.6-0.7-0.2-0.9-0.9-1.40.1-0.8-0.9
Cocaine response after cond. not corrected1.41.53.5-0.6-1.0-1.1-1.3-0.6-1.6-1.6-1.9-0.4-1.4-1.3
Cocaine response before conditioning0.30.41.1-0.5-1.1-0.4-0.6-0.2-0.9-0.8-0.5-0.4-0.6-0.2
Saline control response0.20.20.80.40.30.30.10.5-0.4-0.3-0.90.8-0.2-0.2
Condit. Reinf. active minus inactive responses0.20.21.2-0.4-0.00.00.00.2-0.4-0.0-0.71.1-0.3-0.1
Condit. Reinf. active-inactive response ratio0.10.10.7-0.80.10.10.20.10.00.4-0.50.6-0.10.1
Condit. Reinf. active responses0.20.30.70.1-0.4-0.2-0.40.4-0.8-0.8-0.80.2-0.6-0.2
Condit. Reinf. inactive responses1.21.54.11.0-1.1-0.9-1.4-0.1-1.6-2.0-1.1-0.9-1.2-1.1
Condit. Reinf. lever presses1.01.42.70.5-1.6-1.1-1.5-0.8-1.5-1.6-0.5-1.1-1.2-1.1
Condit. Reinf. lever reinforcers received0.30.41.20.1-0.5-0.4-0.60.1-1.0-1.0-1.10.4-0.8-0.5
Pavlov. Cond. lever latency0.30.41.8-1.30.2-0.00.5-0.50.70.90.7-0.00.40.4
Pavlov. Cond. magazine entry latency3.94.47.2-0.8-1.9-2.0-2.4-1.4-2.5-2.7-2.5-1.2-2.5-2.2
Pavlov. Cond. change in total contacts0.50.72.51.6-0.6-0.3-0.90.3-1.0-1.2-0.70.0-0.6-0.7
Pavlov. Cond. index score0.81.02.31.0-0.7-0.6-1.10.0-1.4-1.5-1.3-0.2-1.0-1.0
Pavlov. Cond. latency score0.81.12.20.5-0.8-0.8-1.2-0.3-1.3-1.5-1.3-0.3-1.2-1.1
Pavlov. Cond. lever contacts0.30.51.91.4-0.3-0.0-0.60.4-0.8-1.0-0.7-0.2-0.5-0.5
Pavlov. Cond. magazine entry number0.81.03.2-0.10.40.81.10.21.31.31.8-0.01.21.1
Pavlov. Cond. intertrial magazine entries1.21.63.10.90.81.21.30.71.41.71.81.01.51.3
Pavlov. Cond. lever-magazine prob. diff.0.81.12.41.0-0.8-0.6-1.20.0-1.4-1.6-1.4-0.2-1.1-1.0
Pavlov. Cond. response bias0.71.02.51.4-0.5-0.3-1.00.4-1.4-1.6-1.4-0.3-0.9-0.8
Conditioned reinforcement - actives0.50.51.40.7-0.00.70.40.60.70.31.2-0.90.81.0
Conditioned reinforcement - inactives1.11.24.20.60.30.60.70.11.51.12.0-1.61.11.0
Conditioned locomotion0.40.51.80.4-1.0-0.1-0.50.3-0.6-1.2-0.2-1.3-0.20.1
Intermittent access intake day 1-15 change2.42.44.31.52.11.61.61.51.81.21.40.71.61.7
Intermittent access intake escalation1.21.22.01.01.41.11.11.11.40.81.00.51.11.2
Intermittent access intake escalation 20.90.91.90.91.40.91.00.81.20.80.80.70.90.9
Intermitt. access day 1 inactive lever presses0.50.53.20.2-0.4-0.2-0.3-0.60.60.31.3-1.80.10.1
Intermitt. access day 15 inactive lever presses0.30.31.1-0.20.2-0.3-0.0-0.90.80.71.1-0.50.2-0.0
Intermitt. access escalation Index0.30.31.20.5-0.20.80.51.1-0.1-0.2-0.10.40.50.7
Intermittent access day 1 total infusions1.61.84.70.11.41.01.50.41.82.21.50.71.41.2
Intermittent access day 15 total infusions1.71.93.60.51.71.31.61.01.91.71.40.81.51.4
Intermittent access terminal intake (last 3 days)1.41.53.3-0.11.51.01.40.51.61.81.11.11.21.1
Intermittent access total infusions1.11.22.7-0.21.20.91.30.41.51.71.10.51.11.1
Intermittent access day 1 locomotion0.90.92.8-1.1-1.2-1.2-0.7-1.7-0.2-0.00.5-1.2-0.6-0.7
Intermittent access day 15 total locomotion0.60.62.1-1.4-0.1-0.6-0.0-1.10.70.40.6-1.4-0.1-0.1
Intermittent access total locomotion0.40.52.2-1.1-0.6-0.6-0.3-0.90.1-0.20.1-1.5-0.4-0.2
Intermittent access standard deviation3.73.96.82.02.41.91.91.72.61.72.2-0.72.12.0
Cocaine induced anxiety0.70.81.90.90.51.10.91.40.70.30.9-0.21.01.3
Post-drug Anxiety0.50.61.80.80.3-0.2-0.60.5-0.9-1.3-1.2-0.0-0.7-0.6
Baseline Anxiety1.92.14.4-0.1-0.3-1.3-1.6-1.1-1.8-1.3-1.91.2-1.6-2.1
Lifetime Intake0.91.02.3-0.00.80.81.10.21.41.51.40.21.01.0
Incentive Sensitization - Responses1.61.63.9-0.72.00.81.30.22.01.91.1-0.21.11.0
Incentive Sensitization - Breakpoint2.02.05.2-0.82.30.91.50.22.22.11.00.01.21.1
Progressive ratio test 1 active lever presses0.70.73.80.3-0.7-0.10.1-0.60.90.71.9-1.10.80.5
Progressive ratio test 1 breakpoint0.70.83.90.2-0.7-0.00.2-0.61.00.82.0-1.00.80.6
Progressive ratio test 1 inactive lever presses1.01.14.0-0.5-1.0-0.6-0.3-1.50.91.02.0-1.50.30.1
Progressive ratio test 2 active lever presses0.90.92.6-0.90.90.20.7-0.51.61.41.2-0.90.70.6
Progressive ratio test 2 breakpoint0.70.72.0-0.70.90.10.5-0.51.41.21.1-1.10.60.5
Progressive ratio test 2 inactive lever presses2.32.76.70.51.61.01.40.12.62.22.6-0.91.71.5
Total sessions with >9 infusions0.40.41.8-0.4-0.50.00.2-0.50.60.91.3-0.10.60.5
Short access day 1 total inactive lever presses0.30.31.0-0.4-0.3-0.7-0.5-1.0-0.10.10.5-0.8-0.3-0.4
Short access day 10 total inactive lever presses1.01.12.8-0.2-1.1-1.2-1.3-1.3-0.7-1.00.1-1.7-0.8-1.0
Short access day 1 total infusions1.51.63.31.30.61.21.20.91.21.51.80.51.51.5
Short access day 10 total infusions1.92.04.70.81.01.21.40.71.91.92.2-0.31.61.6
Short access total infusions0.50.51.50.30.30.50.70.00.91.21.2-0.00.70.7
Short access day 1 locomotion0.50.62.30.8-1.30.1-0.40.2-0.5-0.60.6-1.50.00.4
Short access day 10 total locomotion0.20.21.10.3-0.6-0.0-0.1-0.0-0.0-0.10.6-1.10.00.2
Short access total locomotion0.60.62.9-0.2-1.3-0.5-0.5-0.7-0.2-0.40.8-1.7-0.20.0
Compulsive drug intake2.12.16.7-0.7-0.6-1.1-1.3-0.5-1.7-2.0-2.6-0.0-1.8-1.6
One hour access (0.3 mA shock)0.70.81.30.21.21.01.10.91.10.90.60.10.91.0
One hour access (shock baseline)1.01.11.80.40.71.11.20.81.21.31.40.21.21.3
Number of responses in last shaping day0.20.20.9-0.9-1.0-0.3-0.3-0.5-0.30.10.30.10.00.1
Context. condit. distance diff. score1.21.52.31.51.01.21.01.20.91.31.21.41.41.1
Locomotion velocity, session 11.21.33.6-1.00.0-1.1-0.9-1.2-0.8-0.9-1.9-0.6-1.6-1.5
Locomotion distance, session 10.91.12.0-0.3-1.0-0.8-1.1-0.7-1.2-1.4-1.0-1.4-1.2-1.0
Locomotion velocity, session 20.30.40.8-0.2-0.5-0.6-0.6-0.7-0.9-0.8-0.4-0.6-0.7-0.6
Locomotion distance, session 20.20.30.60.80.50.70.60.70.20.10.4-0.10.50.6
Locomotion velocity, session 32.52.97.1-0.5-0.8-1.5-1.8-1.0-2.0-2.0-2.7-0.2-2.1-2.1
Locomotion distance, session 30.80.92.4-0.1-0.0-0.9-1.0-0.7-0.8-0.9-1.5-0.2-1.3-1.4
Stereotopy head waving bouts, day 31.41.62.70.81.21.61.51.61.11.00.81.11.41.5
Stereotopy head waving duration, day 30.10.20.30.50.10.50.40.40.30.30.50.30.40.5
Locomotion velocity, session 72.93.25.2-0.7-1.5-2.0-2.2-1.8-1.8-1.9-1.5-1.1-2.1-2.3
Locomotion distance, session 70.00.00.10.3-0.1-0.1-0.3-0.0-0.2-0.3-0.2-0.0-0.2-0.3
Stereotopy head waving bouts, day 70.30.31.5-0.60.2-0.2-0.10.1-0.4-0.4-1.20.7-0.6-0.4
Stereotopy head waving duration, day 70.50.61.3-1.1-0.4-0.8-0.6-0.7-0.8-0.7-1.10.0-1.0-0.7
Locomotion velocity, session 80.91.02.00.9-0.4-0.8-1.2-0.4-1.4-1.2-1.30.2-1.1-1.4
Locomotion distance, session 81.11.63.31.81.21.41.21.41.01.11.20.61.41.3
Degree of sensitization distance0.70.72.10.60.10.80.70.60.80.81.4-0.01.11.0
Degree of sensitization stereotypy1.51.74.8-1.3-0.6-1.1-1.0-0.8-1.3-1.4-2.2-0.1-1.7-1.4
Condit. Reinf. active minus inactive responses3.13.46.70.7-2.5-2.0-2.4-1.6-1.7-2.1-0.2-2.6-1.6-1.5
Condit. Reinf. active-inactive response ratio1.82.04.10.5-2.0-1.7-1.9-1.6-1.3-1.4-0.0-1.3-1.2-1.4
Condit. Reinf. active responses1.51.83.50.7-1.8-1.4-1.7-1.1-1.3-1.5-0.2-1.9-1.2-1.1
Condit. Reinf. inactive responses0.10.10.50.30.70.50.30.4-0.00.2-0.30.50.10.1
Incentive salience index mean1.51.85.10.5-1.7-1.4-1.6-1.2-1.1-1.5-0.0-2.3-1.1-0.9
Condit. Reinf. lever presses0.30.41.60.1-0.6-0.5-0.6-0.4-0.6-0.8-0.2-1.2-0.6-0.3
Time in familiar zone, hab. session 11.31.22.01.00.61.31.11.20.90.91.40.51.31.4
Time in novel zone, hab. session 10.60.61.9-0.3-0.7-0.5-0.7-0.1-1.0-1.1-1.4-0.4-0.9-0.6
Total zone transitions, hab. session 11.62.24.70.6-1.1-1.2-1.7-0.5-2.0-2.2-1.9-1.1-1.6-1.6
Total locomotion distance, hab. session 10.30.51.20.5-0.20.3-0.11.0-0.8-1.1-1.1-0.8-0.30.1
Locomotion velocity, hab. session 10.20.30.90.80.10.40.11.0-0.3-0.6-0.4-0.80.10.3
Time in familiar zone, hab. session 20.90.91.70.71.31.11.01.11.00.90.50.81.00.9
Time in novel zone, hab. session 20.70.71.6-0.4-1.3-1.0-0.9-1.0-0.8-0.8-0.3-0.8-0.9-0.7
Total zone transitions, hab. session 20.81.12.51.4-1.0-0.4-1.00.1-1.4-1.6-0.9-0.9-0.9-0.7
Total locomotion distance, hab. session 20.70.92.81.50.31.20.81.70.2-0.10.4-0.30.91.1
Locomotion velocity, hab. session 20.50.72.21.40.21.00.71.50.1-0.20.3-0.40.71.0
Novel to familiar place preference ratio0.30.30.7-0.30.60.50.70.40.70.70.20.80.40.5
Novelty place preference0.50.51.1-0.00.80.80.90.70.70.80.21.00.60.7
Time in novel zone, NPP test0.40.40.90.00.60.70.70.60.60.70.20.90.50.6
Total zone transitions, NPP test0.71.02.00.8-0.9-0.8-1.2-0.5-1.2-1.4-1.1-0.9-1.1-1.1
Total locomotion distance, NPP test0.81.12.10.61.01.31.31.51.10.80.6-0.01.11.4
Locomotion velocity, NPP test0.81.12.00.31.21.31.41.41.20.80.5-0.21.11.4
Pavlov. Cond. lever latency0.50.61.40.30.60.80.80.50.91.20.90.71.00.7
Pavlov. Cond. magazine entry latency1.21.53.61.71.91.31.21.50.90.80.20.91.11.0
Pavlov. Cond. change in total contacts0.20.20.60.20.60.70.70.80.20.10.10.20.40.7
Pavlov. Cond. index score0.30.41.20.71.10.70.61.00.30.1-0.30.40.40.5
Pavlov. Cond. latency score0.30.31.00.61.00.60.60.90.20.0-0.40.50.30.5
Pavlov. Cond. lever contacts0.10.20.70.20.2-0.1-0.20.1-0.5-0.7-0.8-0.0-0.5-0.3
Pavlov. Cond. magazine entry number0.20.31.0-0.7-1.0-0.5-0.5-0.7-0.3-0.10.1-0.2-0.4-0.4
Pavlov. Cond. intertrial magazine entries0.20.20.9-0.2-0.3-0.2-0.4-0.2-0.7-0.1-0.61.0-0.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.40.51.30.71.10.80.81.00.50.2-0.00.30.60.7
Pavlov. Cond. response bias0.20.20.80.90.90.50.40.60.2-0.0-0.20.00.20.3
Bone: apparent density0.00.10.4-0.10.70.20.30.00.40.20.10.10.20.1
Bone surface0.20.30.9-0.9-0.0-0.4-0.3-0.4-0.5-0.4-1.00.4-0.6-0.6
Bone volume0.20.41.3-0.70.1-0.5-0.5-0.4-0.6-0.6-1.10.1-0.7-0.8
Bone: connectivity density0.10.10.2-0.50.20.20.3-0.10.40.40.40.10.30.3
Bone: cortical apparent density0.71.01.70.90.61.11.00.81.21.01.3-0.21.21.1
Bone: cortical area0.50.73.71.9-0.60.2-0.60.8-1.2-1.1-0.40.2-0.2-0.3
Bone: cortical porosity0.20.20.7-0.50.4-0.30.1-0.60.30.60.10.90.0-0.3
Bone: cortical porosity0.20.20.7-0.40.5-0.4-0.1-0.50.00.2-0.40.9-0.3-0.5
Bone: cortical thickness1.52.59.63.10.81.81.12.20.60.41.40.71.71.5
Bone: cortical thickness0.20.20.90.6-0.0-0.1-0.30.1-0.5-0.1-0.50.9-0.2-0.5
Bone: cortical tissue density0.60.81.40.70.61.00.90.71.10.91.2-0.21.11.0
Bone: elastic displacement0.30.30.70.40.50.50.60.40.80.60.8-0.10.70.6
Bone: elastic work1.11.47.22.70.31.20.61.60.3-0.11.2-0.51.11.1
Bone: endosteal estimation2.86.110.0-2.1-2.2-2.5-2.6-1.9-2.9-2.6-3.2-0.4-2.9-2.7
Bone: endosteal perimeter0.91.93.4-0.8-1.6-1.3-1.6-0.9-1.8-1.7-1.4-0.6-1.6-1.3
Bone: final force0.30.41.50.4-1.2-0.1-0.60.1-1.2-1.0-0.30.0-0.4-0.3
Bone: final moment0.30.51.60.4-1.2-0.1-0.70.2-1.2-1.1-0.40.0-0.4-0.3
Bone: marrow area2.65.69.8-2.0-2.0-2.3-2.4-1.8-2.8-2.5-3.1-0.3-2.8-2.5
Bone: maximum diameter1.12.04.40.1-1.3-1.1-1.6-0.5-2.1-2.0-1.7-0.3-1.6-1.5
Bone: maximum force0.40.61.80.6-1.1-0.2-0.80.2-1.3-1.3-0.6-0.2-0.5-0.4
Bone: maximum moment0.40.62.00.6-1.1-0.2-0.80.3-1.3-1.4-0.7-0.3-0.6-0.4
Bone: minimum diameter2.13.98.20.2-2.0-1.6-2.3-0.8-2.9-2.8-2.4-0.3-2.0-2.1
Bone: periosteal estimation1.63.37.1-0.2-1.8-1.4-2.1-0.7-2.7-2.5-2.3-0.2-2.0-1.9
Bone: periosteal perimeter1.32.15.10.4-1.5-1.0-1.6-0.3-2.3-2.1-1.8-0.0-1.5-1.4
Bone: post-yield work2.23.04.9-0.6-1.4-1.6-2.0-1.2-2.1-2.2-2.1-1.3-2.0-1.9
Bone: stiffness0.00.10.30.0-0.60.20.00.2-0.3-0.20.30.30.10.3
Bone: tissue strength0.70.61.5-0.10.20.70.80.41.00.51.2-1.10.81.1
Bone: trabecular number0.50.81.9-0.61.20.81.10.11.41.20.90.00.80.8
Bone: trabecular spacing3.34.35.6-1.4-2.2-2.3-2.4-1.9-2.3-2.2-1.9-1.3-2.3-2.2
Bone: trabecular thickness0.10.10.20.50.20.1-0.20.1-0.2-0.1-0.40.4-0.2-0.3
Bone: trabecular tissue density0.10.10.90.90.40.20.10.3-0.00.10.00.30.1-0.1
Breakpoint value in progressive ratio session0.10.10.3-0.1-0.00.20.20.10.1-0.00.4-0.60.30.3
Distance traveled before self-admin0.30.31.90.90.30.20.10.2-0.3-0.1-0.31.4-0.0-0.3
Distance traveled after self-admin0.10.10.30.4-0.30.1-0.0-0.00.2-0.40.50.00.30.1
Delta time in closed arm before/after self-admin0.30.31.20.2-1.10.1-0.20.4-1.0-0.6-0.1-0.1-0.10.2
Delta time in open arm before/after self-admin1.51.42.4-0.5-1.0-1.5-1.5-1.3-0.8-1.3-0.6-1.5-1.1-1.2
Diff in mean of infusions in LGA sessions0.30.31.91.4-0.20.50.00.6-0.4-0.70.2-0.10.20.2
Extinction: sum of active levers before priming2.42.45.3-0.0-2.2-1.5-1.8-1.6-1.3-1.7-0.2-2.3-1.4-1.3
Active lever presses in extinction session 60.60.62.00.2-1.3-0.3-0.7-0.3-0.8-1.00.4-1.4-0.3-0.2
Delta distance traveled before/after self-admin0.60.72.2-0.7-1.3-0.6-0.8-0.5-0.5-1.20.0-1.5-0.5-0.2
Delta ambulatory time before/after self-admin0.70.73.4-0.6-1.3-0.6-0.8-0.7-0.1-0.70.6-1.8-0.2-0.0
Time in closed arm before self-admin0.10.10.50.30.7-0.2-0.1-0.30.60.3-0.10.00.1-0.4
Time in closed arm after self-admin0.50.61.71.30.40.80.60.80.50.50.70.60.90.8
Time in open arm before self-admin0.30.31.01.00.30.80.60.9-0.10.20.00.70.30.5
Time in open arm after self-admin0.50.62.10.1-0.8-0.7-0.8-0.4-0.6-1.1-0.3-1.4-0.7-0.5
Sum of active levers in priming session hrs 5-60.10.10.3-0.1-0.5-0.1-0.30.1-0.4-0.5-0.1-0.5-0.10.0
Time to tail flick, vehicle, before self-admin0.80.82.8-0.50.8-0.30.4-1.11.11.71.01.20.5-0.1
Time to tail flick, vehicle, after self-admin1.81.95.60.1-1.1-1.6-1.6-1.4-1.0-1.4-0.8-2.4-1.4-1.4
Time to tail flick, test, before self-admin0.70.71.8-1.30.0-0.9-0.7-0.9-0.7-0.1-1.20.7-0.9-1.0
Time to tail flick, test, after self-admin0.20.30.5-0.60.3-0.40.2-0.70.60.70.5-0.70.10.1
Delta time to tail flick, vehicle, before/after SA1.31.36.30.8-1.2-0.5-0.90.1-0.9-1.6-0.4-2.5-0.8-0.4
Delta time to tail flick, test, before/after SA0.10.10.90.2-0.10.00.20.20.2-0.10.2-0.90.10.3
Ambulatory time before self-admin0.20.21.70.60.20.20.10.2-0.4-0.1-0.31.3-0.0-0.2
Ambulatory time after self-admin0.10.10.40.3-0.6-0.2-0.3-0.3-0.1-0.50.4-0.50.0-0.1
Total heroin consumption0.70.92.60.60.20.80.90.61.00.71.6-0.71.21.1
Area under the delay curve0.30.40.70.30.70.60.70.70.70.70.3-0.20.50.8
Delay disc. indifference point, 0s delay0.40.51.30.41.00.60.71.00.40.5-0.31.10.40.4
Delay disc. indifference point, 16s delay0.20.21.41.20.50.40.20.50.20.1-0.1-0.00.10.1
Delay disc. indifference point, 2s delay0.91.01.6-1.1-0.7-1.3-1.0-1.0-0.8-0.6-1.0-0.7-1.2-1.0
Delay disc. indifference point, 24s delay0.10.10.30.00.10.50.40.30.30.20.2-0.50.10.5
Delay disc. indifference point, 4s delay0.20.20.60.7-0.10.30.20.70.20.10.4-0.60.40.7
Delay disc. indifference point, 8s delay1.31.32.40.51.51.31.51.11.31.40.50.51.01.4
Delay discount exponential model param0.40.40.8-0.3-0.7-0.6-0.7-0.7-0.8-0.8-0.40.3-0.5-0.9
Delay discount hyperbolic model param0.20.20.5-0.1-0.5-0.4-0.5-0.5-0.5-0.6-0.30.4-0.3-0.7
Fecal boli incidents, locomotor time 11.01.13.3-1.31.80.21.0-0.30.91.6-0.61.50.10.1
Change in fecal boli incidents, locomotor task2.12.03.20.41.21.51.61.41.71.41.60.41.71.8
Time >=10cm from walls, locomotor time 10.20.20.80.90.30.1-0.20.4-0.1-0.6-0.5-0.9-0.2-0.2
Bouts of movement, locomotor time 10.10.10.50.10.7-0.10.1-0.20.20.2-0.30.6-0.2-0.2
Total resting periods, locomotor time 10.10.10.50.20.70.00.1-0.10.20.1-0.30.5-0.2-0.1
Rest time, locomotor task time 11.31.45.1-1.40.5-0.9-0.5-0.8-1.0-0.5-2.31.2-1.3-1.4
Distance moved, locomotor task time 11.01.13.80.6-0.10.60.50.51.20.61.9-1.31.31.3
Vertical activity count, locomotor time 10.30.31.40.2-0.20.20.00.20.60.30.9-1.20.60.6
Time >=10cm from walls, locomotor time 21.11.25.3-0.30.1-0.7-0.8-0.1-1.2-1.2-2.30.4-1.3-1.4
Bouts of movement, locomotor time 20.91.04.1-2.0-0.3-1.1-0.8-1.3-0.3-0.5-0.9-0.8-1.0-0.9
Total resting periods, locomotor time 21.21.34.6-2.1-0.4-1.2-0.9-1.3-0.5-0.7-1.2-0.8-1.2-1.0
Rest time, locomotor task time 20.40.51.9-0.9-0.2-0.6-0.4-0.5-0.5-0.8-1.4-0.1-0.9-0.7
Distance moved, locomotor task time 20.20.21.80.4-0.1-0.3-0.5-0.0-0.1-0.50.2-1.3-0.1-0.2
Vertical activity count, locomotor time 20.00.00.1-0.30.3-0.10.1-0.10.00.4-0.10.2-0.0-0.1
Weight adjusted by age1.61.83.50.1-1.6-1.0-1.6-0.4-1.9-1.8-1.6-0.8-1.4-1.3
Seeking ratio, delayed vs. immediate footshock1.01.12.41.50.41.40.91.60.70.31.0-0.61.01.5
Locomotion in novel chamber2.83.45.41.31.62.01.82.01.51.71.52.32.12.0
Locomotion in novel chamber post-restriction0.81.02.50.40.21.11.01.11.00.61.30.21.31.6
Progressive ratio1.31.53.7-1.6-0.6-1.7-1.1-1.9-0.7-0.4-0.90.3-1.3-1.6
Food seeking constrained by brief footshock0.20.20.90.2-0.2-0.7-0.5-1.0-0.00.40.60.30.1-0.5
Seeking ratio, punishment vs. effort0.91.12.71.70.61.20.91.10.90.71.20.01.31.1
Run reversals in cocaine runway, females0.40.40.80.00.40.50.70.70.40.70.70.60.80.9
Run reversals in cocaine runway, males1.11.13.20.4-1.4-1.1-1.1-1.4-0.3-0.70.9-1.8-0.5-0.6
Latency to leave start box in cocaine runway0.91.04.40.70.31.40.92.1-0.3-0.5-0.70.70.51.2
Latency to leave start box in cocaine runway, F0.10.20.5-0.10.10.40.40.7-0.2-0.2-0.50.70.10.3
Latency to leave start box in cocaine runway, M1.31.25.50.90.41.71.12.3-0.0-0.3-0.40.20.71.5
Cd content in liver0.50.62.41.00.40.90.61.5-0.00.0-0.10.60.80.9
Co content in liver1.41.74.0-2.01.70.31.2-0.41.82.00.51.10.70.5
Cu content in liver0.30.30.60.40.70.80.70.80.40.40.60.10.70.7
Fe content in liver3.74.47.0-1.6-2.7-2.3-2.2-2.4-2.1-2.0-1.2-2.1-2.2-1.9
K content in liver0.30.31.2-1.10.4-0.20.2-0.60.60.50.4-0.60.10.0
Mg content in liver0.30.32.1-1.40.4-0.30.1-0.80.40.70.20.1-0.1-0.2
Mn content in liver0.30.31.0-0.30.80.00.5-0.50.81.00.70.30.30.1
Na content in liver6.46.89.9-2.3-2.1-3.1-2.9-3.2-2.4-2.3-2.1-1.7-2.9-3.1
Rb content in liver0.10.10.4-0.60.1-0.10.2-0.10.50.40.5-0.40.20.3
Se content in liver2.22.74.40.51.71.92.11.71.81.51.30.61.82.1
Sr content in liver3.33.04.51.21.81.71.91.32.12.02.00.71.91.8
Zn content in liver1.51.63.91.41.01.11.00.81.51.32.0-0.11.61.3