Hub : Genes

Tex2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000013659 0.25 0.08 9.1e-13 0.06 0.09 0.08 0.1 2.6e-07 5.0e-10 1.6e-09 9.8e-11
2 Adipose mRNA stability ENSRNOG00000013659 0.04 0.03 2.3e-03 0.01 0.01 0 0.01 4.4e-02 7.9e-03 7.3e-02 1.9e-02
3 BLA gene expression ENSRNOG00000013659 0.4 0.11 0.0e+00 0.37 0.38 0.4 0.4 7.3e-21 1.3e-21 1.0e-22 1.0e-22
4 Brain gene expression ENSRNOG00000013659 0.22 0.07 0.0e+00 0.25 0.26 0.24 0.25 7.8e-23 1.1e-23 2.6e-22 2.4e-23
5 Brain mRNA stability ENSRNOG00000013659 0.15 0.07 7.0e-06 0.07 0.05 0.05 0.06 9.3e-07 1.5e-05 2.6e-05 3.9e-06
6 IL gene expression ENSRNOG00000013659 0.22 0.11 6.3e-04 0.1 0.13 0.09 0.09 2.5e-03 6.4e-04 3.3e-03 4.6e-03
7 LHb gene expression ENSRNOG00000013659 0.3 0.12 2.8e-05 0.26 0.14 0.04 0.22 7.5e-07 2.7e-04 4.1e-02 7.3e-06
8 Liver gene expression ENSRNOG00000013659 0.09 0.04 2.7e-08 0.09 0.08 0.09 0.09 2.7e-10 3.4e-09 9.8e-10 2.5e-10
9 Liver intron excision ratio chr10:91499042:91517657 0.42 0.09 0.0e+00 0.44 0.44 0.45 0.46 1.5e-53 2.0e-54 1.6e-55 2.8e-56
10 Liver intron excision ratio chr10:91499042:91546090 0.21 0.07 0.0e+00 0.18 0.17 0.18 0.18 1.1e-19 1.0e-18 1.8e-19 1.1e-19
11 Liver mRNA stability ENSRNOG00000013659 0.16 0.07 6.9e-05 0.04 0.04 0.03 0.04 9.4e-06 2.6e-05 1.2e-04 2.9e-05
12 NAcc gene expression ENSRNOG00000013659 0.35 0.11 0.0e+00 0.22 0.28 0.28 0.28 5.5e-16 1.2e-20 6.5e-21 2.3e-21
13 OFC gene expression ENSRNOG00000013659 0.59 0.13 3.3e-08 0.23 0.2 0.17 0.22 3.3e-06 1.9e-05 8.5e-05 6.2e-06
14 PL gene expression ENSRNOG00000013659 0.3 0.09 0.0e+00 0.35 0.34 0.36 0.36 2.5e-27 8.3e-27 1.7e-28 1.6e-28

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.30.94.3-0.21.5-0.01.02.1-0.70.9-1.3-0.0-0.31.0-1.00.60.3
BMI without tail1.02.15.90.40.71.52.32.40.72.0-0.3-1.51.10.90.42.21.4
Body weight1.35.511.11.6-0.72.83.30.92.03.02.1-2.62.3-0.42.63.12.7
Epididymis fat weight0.71.64.40.10.51.51.22.11.41.7-0.1-1.20.90.80.41.71.7
Glucose0.60.91.60.20.6-1.1-1.0-0.7-1.2-1.1-0.31.1-1.0-0.7-0.8-1.2-1.3
Heart weight0.20.31.61.30.7-0.30.1-0.5-0.50.20.30.2-0.3-0.90.20.1-0.2
Left kidney weight0.82.35.01.91.9-1.8-0.8-1.5-2.2-1.1-0.11.6-1.7-1.7-0.5-1.3-1.7
Right kidney weight0.61.74.32.11.4-1.2-0.7-1.7-1.6-0.90.61.1-1.2-2.00.0-1.0-1.2
Tail length1.54.67.81.0-1.32.72.40.62.52.41.9-2.62.4-0.22.52.82.5
Length with tail1.76.112.52.0-1.82.82.3-1.22.72.33.4-2.52.4-1.53.52.52.5
Length without tail0.51.24.21.0-0.90.80.3-1.61.00.52.0-0.60.6-1.31.70.40.8
Liver weight, left1.22.05.61.5-1.21.31.1-1.51.10.72.4-1.11.2-1.62.01.11.1
Liver weight, right1.32.26.52.52.0-1.0-1.0-1.7-1.3-1.10.81.4-1.5-2.50.1-1.1-1.0
Parametrial fat weight0.50.91.91.00.21.20.1-0.21.30.81.0-1.00.8-0.81.11.41.2
Retroperitoneal fat weight1.03.27.1-0.1-0.92.71.81.62.22.50.8-1.91.81.01.42.12.2
Intraocular pressure0.60.94.4-0.10.70.61.02.10.41.4-0.5-0.70.51.1-0.11.20.9
Extensor digitorum longus weight1.35.417.9-2.92.1-0.8-1.23.5-1.1-0.8-4.21.3-1.63.1-3.6-0.7-0.8
Soleus weight0.10.30.80.5-0.3-0.20.9-0.6-0.10.20.7-0.60.5-0.40.80.50.4
Tibialis anterior weight0.72.67.9-2.4-0.11.01.32.80.81.3-1.6-1.10.92.8-0.81.41.4
Tibia length0.72.07.62.81.2-0.8-0.3-2.2-1.0-0.21.50.8-0.9-2.61.0-0.6-0.6
Number of licking bursts0.30.31.30.9-0.3-0.0-0.1-1.1-0.1-0.30.70.1-0.1-1.10.5-0.0-0.2
Food consumed during 24 hour testing period2.53.05.4-0.4-1.02.32.11.51.82.20.8-2.12.01.01.22.32.1
Times rat made contact with spout0.50.61.00.1-0.81.00.70.01.00.80.6-1.00.9-0.10.80.90.9
Mean time between licks in bursts0.10.20.70.90.40.40.3-0.30.30.40.6-0.1-0.0-0.50.60.30.4
Mean num. licks in bursts0.50.52.0-0.80.10.50.51.40.60.9-0.6-0.60.61.2-0.10.70.8
Std. dev. time between licks in bursts0.10.20.8-0.50.30.10.10.90.1-0.1-0.6-0.1-0.10.7-0.40.30.2
Water consumed over 24 hours0.00.00.40.30.60.10.10.2-0.10.2-0.20.0-0.1-0.1-0.10.20.0
Indifference point 0 sec3.25.110.20.8-1.22.73.20.92.23.22.1-2.52.30.42.62.62.7
Indifference point AUC1.21.43.10.1-0.91.41.80.11.11.51.0-1.31.40.21.41.21.5
Indifference point function ln k0.40.61.20.80.9-1.1-0.8-0.3-1.1-0.9-0.00.7-0.9-0.9-0.5-0.4-0.9
Indifference point function log k0.40.61.20.80.9-1.1-0.8-0.3-1.1-0.9-0.00.7-0.9-0.9-0.5-0.4-0.9
Delay discounting total patch changes 0 sec3.35.411.00.9-1.22.73.10.72.33.32.2-2.52.30.32.72.72.7
Delay discounting total patch changes 12 sec5.16.811.50.6-2.13.33.30.42.93.42.4-2.82.80.33.12.73.1
Delay discounting total patch changes 18 sec2.43.16.2-0.1-1.52.02.50.81.82.51.3-2.02.10.81.81.82.0
Delay discounting total patch changes 24 sec2.93.76.71.4-0.81.92.6-0.01.72.62.2-2.01.9-0.52.62.12.2
Delay discounting total patch changes 6 sec1.82.75.30.6-1.01.92.30.41.62.31.6-1.81.7-0.02.01.82.0
Delay discounting time to switch 0 sec0.30.51.3-1.2-0.2-0.5-1.00.6-0.1-0.7-1.00.5-0.30.9-0.9-0.8-0.6
Delay discounting water rate 0 sec0.91.43.90.3-0.11.41.60.71.12.00.7-1.31.00.61.11.61.5
Delay discounting water rate 12 sec1.62.43.81.62.0-1.8-1.5-1.0-1.9-1.4-0.41.7-1.8-1.7-1.0-1.5-1.7
Delay discounting water rate 18 sec0.70.92.91.60.8-0.8-0.4-1.6-0.9-0.40.90.6-0.7-1.70.3-0.5-0.7
Delay discounting water rate 24 sec0.40.52.11.50.3-0.2-0.4-1.3-0.4-0.20.80.4-0.5-1.40.3-0.4-0.4
Delay discounting water rate 6 sec0.40.62.01.11.4-0.9-0.7-0.6-0.9-0.4-0.00.6-0.9-0.9-0.2-0.3-0.6
Locomotor activity0.50.82.7-0.4-1.20.71.60.20.11.00.8-1.11.20.60.71.10.3
Locomotor testing distance1.62.65.9-1.3-1.81.22.41.40.91.90.4-2.02.11.80.91.91.2
Locomotor testing rearing2.33.78.7-2.7-2.61.41.92.41.31.7-0.5-2.02.12.90.11.61.1
Light reinforcement 10.30.51.60.30.80.11.30.9-0.11.0-0.1-0.60.50.50.21.00.7
Light reinforcement 20.40.51.50.10.70.21.00.60.30.80.3-0.80.70.50.51.20.8
Reaction time number correct1.41.95.32.31.6-1.0-1.1-1.6-1.3-1.30.61.3-1.4-2.2-0.1-1.0-1.2
Reaction time mean minus median0.50.61.5-0.90.5-0.5-0.91.2-0.2-0.6-1.20.6-0.70.8-0.9-0.6-0.5
Reaction time mean minus median AUC0.91.22.00.41.2-1.2-1.3-0.2-1.2-1.4-0.71.3-1.4-0.5-0.9-1.3-1.3
Reaction time num false alarms2.53.46.81.0-1.81.82.4-0.81.61.62.3-2.12.3-0.62.62.01.7
Reaction time num false alarms AUC2.83.97.61.1-1.82.02.4-0.81.91.72.5-2.32.4-0.62.82.11.9
Reaction time trials correct on left1.41.95.32.31.6-1.0-1.1-1.6-1.3-1.30.61.3-1.4-2.2-0.1-1.0-1.2
Reaction time trials on left1.42.05.42.31.7-1.0-1.2-1.6-1.3-1.30.61.3-1.4-2.2-0.1-1.0-1.2
Reaction time mean0.60.82.0-0.40.4-1.1-1.3-0.1-0.7-1.1-0.91.1-1.00.1-0.9-1.4-1.1
Reaction time mean AUC0.81.12.2-0.80.3-1.2-1.40.1-0.9-1.3-1.21.2-1.10.4-1.2-1.5-1.2
Median of all reaction times0.60.82.1-0.30.3-1.1-1.2-0.5-0.8-1.1-0.71.1-0.90.0-0.8-1.4-1.1
Reaction time omissions0.20.20.90.30.9-0.2-0.80.60.1-0.6-0.50.4-0.50.0-0.2-0.3-0.1
Reaction time false alarm rate2.94.07.1-0.4-2.52.12.50.12.22.01.7-2.52.70.72.32.12.1
Reaction time premature initiation rate0.70.92.0-0.7-0.20.61.21.20.61.40.0-1.10.91.20.41.41.1
Reaction time premature initiations0.20.30.90.70.60.20.70.2-0.00.70.5-0.50.2-0.10.41.00.5
Std. dev. reaction times0.40.61.4-0.70.4-0.6-1.20.8-0.2-0.8-1.00.8-0.80.6-0.8-0.9-0.6
Reaction time trials completed1.42.05.42.31.7-1.0-1.2-1.6-1.3-1.30.61.3-1.4-2.2-0.1-1.0-1.2
Reaction time trials AUC1.41.95.42.31.7-0.9-1.2-1.5-1.3-1.30.51.3-1.4-2.2-0.2-1.0-1.2
Social response proportion0.20.20.40.50.6-0.4-0.5-0.2-0.5-0.4-0.20.5-0.6-0.5-0.5-0.3-0.5
Social responses0.00.10.30.2-0.40.20.6-0.0-0.10.20.2-0.30.3-0.10.10.20.0
Social time0.10.10.2-0.1-0.4-0.0-0.30.30.40.30.1-0.30.30.1-0.10.30.2
Conditioned locomotion0.70.91.9-0.5-0.70.91.11.11.01.40.2-1.01.00.90.51.11.2
Cocaine response after cond. corrected0.70.81.81.20.8-0.7-1.1-1.3-0.5-0.60.70.9-0.9-1.30.1-0.8-0.7
Cocaine response after cond. not corrected1.21.34.41.00.2-1.2-1.5-2.1-0.8-0.90.91.1-0.9-1.60.1-1.2-1.1
Cocaine response before conditioning0.20.31.5-0.1-0.6-0.8-0.3-1.2-0.5-0.40.20.2-0.1-0.60.1-0.5-0.6
Saline control response2.33.16.1-2.0-1.61.22.22.31.32.1-0.2-1.92.02.50.51.71.7
Condit. Reinf. active minus inactive responses4.96.013.01.8-2.42.12.7-1.62.12.33.5-2.62.6-1.43.62.52.2
Condit. Reinf. active-inactive response ratio2.62.75.50.7-2.01.31.5-1.01.71.52.1-1.91.9-0.62.31.81.5
Condit. Reinf. active responses5.27.212.31.0-2.62.53.4-0.42.63.13.0-3.13.2-0.33.52.92.9
Condit. Reinf. inactive responses1.92.46.20.1-1.01.62.51.01.32.31.0-1.71.80.81.51.71.8
Condit. Reinf. lever presses1.21.63.5-0.3-1.51.01.90.51.11.60.9-1.61.70.61.31.31.2
Condit. Reinf. lever reinforcers received4.25.910.31.0-2.32.33.1-0.32.42.92.8-2.82.9-0.33.22.72.6
Pavlov. Cond. lever latency0.40.51.2-0.50.9-0.4-0.90.6-0.3-0.7-1.10.7-0.70.6-1.1-0.5-0.4
Pavlov. Cond. magazine entry latency1.82.03.70.70.5-1.4-1.5-1.7-1.6-1.7-0.21.7-1.5-1.5-0.8-1.9-1.7
Pavlov. Cond. change in total contacts0.70.92.30.3-1.50.91.2-0.60.80.81.3-1.01.1-0.31.30.70.7
Pavlov. Cond. index score0.20.31.00.6-0.7-0.20.1-1.0-0.2-0.10.80.10.1-0.90.5-0.4-0.3
Pavlov. Cond. latency score0.30.31.40.6-0.6-0.4-0.0-1.2-0.4-0.20.70.2-0.0-1.00.4-0.5-0.5
Pavlov. Cond. lever contacts0.20.30.70.4-0.60.30.8-0.20.30.60.7-0.50.6-0.30.80.40.4
Pavlov. Cond. magazine entry number2.32.85.4-0.7-0.71.91.81.72.01.90.4-2.01.81.61.12.32.1
Pavlov. Cond. intertrial magazine entries10.213.122.5-0.6-2.24.34.02.34.44.62.0-4.44.12.03.14.74.6
Pavlov. Cond. lever-magazine prob. diff.0.30.41.30.7-0.6-0.30.0-1.2-0.3-0.20.80.2-0.0-1.20.5-0.5-0.4
Pavlov. Cond. response bias0.10.20.70.8-0.30.00.3-0.7-0.10.10.70.00.1-0.80.6-0.2-0.1
Conditioned reinforcement - actives0.60.61.1-0.1-0.60.81.00.50.71.00.4-0.90.90.50.81.00.9
Conditioned reinforcement - inactives0.70.81.50.1-0.51.21.20.51.01.10.7-1.01.00.40.91.11.0
Conditioned locomotion1.72.03.4-0.2-0.71.41.60.71.61.81.1-1.71.61.01.61.81.7
Intermittent access intake day 1-15 change0.60.61.5-1.1-1.20.90.21.11.00.5-0.3-0.70.80.7-0.10.50.6
Intermittent access intake escalation0.30.31.1-1.0-0.80.6-0.11.10.60.1-0.6-0.30.40.6-0.50.10.2
Intermittent access intake escalation 20.90.81.8-1.1-1.21.20.31.21.30.7-0.1-0.91.00.90.10.70.8
Intermitt. access day 1 inactive lever presses3.53.86.90.4-2.01.72.5-0.31.92.12.3-2.32.20.12.62.22.0
Intermitt. access day 15 inactive lever presses2.02.24.5-1.5-0.91.01.22.11.51.8-0.5-1.71.72.10.31.81.6
Intermitt. access escalation Index2.82.56.11.30.4-1.4-1.6-2.5-1.6-1.90.31.7-1.5-2.0-0.5-2.0-1.8
Intermittent access day 1 total infusions0.60.71.51.00.20.61.1-0.50.40.91.1-0.80.6-0.41.21.20.7
Intermittent access day 15 total infusions0.40.51.10.1-0.41.10.80.50.80.90.2-0.80.70.10.51.00.8
Intermittent access terminal intake (last 3 days)1.92.13.9-0.0-1.12.01.60.71.71.80.9-1.81.60.51.31.91.7
Intermittent access total infusions2.12.34.10.5-1.01.92.00.31.51.91.4-1.81.70.11.82.01.7
Intermittent access day 1 locomotion2.32.34.70.5-0.61.61.90.41.51.91.5-1.81.60.41.92.21.7
Intermittent access day 15 total locomotion3.84.06.2-0.1-1.52.52.40.72.32.41.7-2.42.20.92.22.52.3
Intermittent access total locomotion5.25.810.0-0.0-1.42.73.01.32.63.01.9-2.92.71.12.63.22.8
Intermittent access standard deviation1.21.22.8-0.9-0.61.11.01.71.11.3-0.3-1.31.21.30.31.41.1
Cocaine induced anxiety0.40.51.30.41.0-1.1-0.90.3-0.8-0.6-0.60.7-0.8-0.4-0.7-0.6-0.6
Post-drug Anxiety0.70.81.90.41.4-1.3-1.30.1-0.8-0.8-0.70.9-1.0-0.5-0.9-0.8-0.7
Baseline Anxiety0.80.91.60.31.3-1.1-1.1-0.5-1.0-1.0-0.61.1-1.1-0.5-0.8-1.1-0.9
Lifetime Intake2.42.75.30.4-1.01.82.30.41.52.11.4-2.01.80.31.82.21.8
Incentive Sensitization - Responses2.92.94.40.4-1.42.01.70.12.02.11.9-1.91.90.12.01.92.1
Incentive Sensitization - Breakpoint2.72.74.10.5-1.41.91.6-0.12.01.92.0-1.81.9-0.12.01.82.0
Progressive ratio test 1 active lever presses3.73.86.71.1-1.31.92.6-0.31.72.32.3-2.22.1-0.32.62.42.1
Progressive ratio test 1 breakpoint4.74.99.30.8-1.52.23.00.12.02.72.3-2.62.40.12.72.92.5
Progressive ratio test 1 inactive lever presses4.14.49.20.9-1.62.03.0-0.41.72.42.5-2.42.3-0.12.72.52.2
Progressive ratio test 2 active lever presses3.84.16.60.7-1.22.22.40.32.22.62.1-2.42.20.22.52.52.5
Progressive ratio test 2 breakpoint4.34.87.90.5-1.52.42.50.32.42.72.2-2.62.50.32.62.82.7
Progressive ratio test 2 inactive lever presses3.33.86.70.6-0.92.32.50.72.02.61.7-2.32.10.42.22.62.4
Total sessions with >9 infusions0.40.41.51.20.6-0.11.0-0.3-0.40.60.7-0.30.1-0.60.70.70.2
Short access day 1 total inactive lever presses0.40.40.80.4-0.30.50.9-0.30.40.70.8-0.80.7-0.30.90.90.5
Short access day 10 total inactive lever presses0.70.71.3-0.4-0.51.11.00.90.91.00.0-1.00.90.80.41.11.0
Short access day 1 total infusions0.90.93.50.8-0.20.61.9-0.20.21.20.9-1.10.9-0.21.11.40.8
Short access day 10 total infusions4.44.88.9-0.0-1.42.53.01.12.22.71.5-2.72.51.02.13.02.5
Short access total infusions2.52.76.70.0-1.31.62.60.61.32.01.2-2.12.00.71.72.31.6
Short access day 1 locomotion2.32.46.00.4-0.11.32.41.21.12.11.0-1.91.60.81.62.41.8
Short access day 10 total locomotion8.18.914.3-0.8-2.13.33.62.53.23.61.7-3.63.41.92.73.83.5
Short access total locomotion3.83.98.3-0.5-1.11.92.91.71.72.41.0-2.52.21.51.82.72.2
Compulsive drug intake1.51.52.70.90.7-1.3-1.5-1.6-1.3-1.40.11.4-1.2-1.4-0.5-1.5-1.4
One hour access (0.3 mA shock)1.01.22.0-0.0-1.31.31.4-0.11.11.11.2-1.31.30.21.21.31.1
One hour access (shock baseline)1.71.93.4-0.6-1.21.71.91.01.51.60.7-1.71.51.01.11.81.6
Number of responses in last shaping day0.40.41.10.2-0.30.20.90.20.40.80.5-0.90.80.20.71.00.6
Context. condit. distance diff. score0.10.10.4-0.6-0.50.20.40.1-0.20.2-0.4-0.00.10.5-0.3-0.0-0.1
Locomotion velocity, session 10.30.40.80.4-0.20.60.4-0.10.70.70.7-0.70.6-0.10.90.80.6
Locomotion distance, session 10.20.21.11.10.90.10.1-0.2-0.20.50.30.3-0.4-0.50.4-0.1-0.1
Locomotion velocity, session 20.50.62.5-0.7-1.60.50.7-0.20.70.60.6-0.81.10.50.70.30.4
Locomotion distance, session 20.10.20.40.6-0.30.20.3-0.6-0.20.10.70.00.1-0.50.6-0.2-0.3
Locomotion velocity, session 30.40.51.40.40.5-1.1-0.3-0.9-1.2-0.7-0.10.7-0.7-0.6-0.3-0.8-0.8
Locomotion distance, session 30.30.31.40.7-0.2-0.20.0-1.2-0.2-0.20.70.1-0.0-0.90.5-0.3-0.2
Stereotopy head waving bouts, day 30.40.51.30.11.1-1.2-0.9-0.2-0.8-0.5-0.40.8-0.9-0.2-0.6-0.6-0.6
Stereotopy head waving duration, day 30.20.30.70.50.9-0.8-0.4-0.5-0.8-0.40.10.6-0.7-0.4-0.2-0.3-0.5
Locomotion velocity, session 70.40.40.8-0.70.4-0.5-0.80.2-0.6-0.6-0.90.7-0.60.5-0.9-0.7-0.6
Locomotion distance, session 70.00.00.20.3-0.00.30.20.30.00.5-0.20.1-0.00.1-0.0-0.1-0.0
Stereotopy head waving bouts, day 70.40.41.50.00.3-1.2-0.6-0.7-1.0-0.5-0.10.7-0.6-0.3-0.4-0.8-0.8
Stereotopy head waving duration, day 71.21.43.3-0.00.3-1.8-1.3-1.4-1.5-1.4-0.21.3-1.1-0.8-0.8-1.5-1.5
Locomotion velocity, session 80.70.92.0-0.6-1.41.30.9-0.31.01.00.6-1.01.10.50.80.80.9
Locomotion distance, session 80.20.20.8-0.2-0.90.60.9-0.10.10.60.3-0.40.50.30.40.30.2
Degree of sensitization distance0.40.41.20.2-0.11.10.60.80.80.9-0.0-0.50.40.40.30.60.6
Degree of sensitization stereotypy0.80.92.1-0.30.1-1.5-0.8-0.7-1.3-1.0-0.51.0-0.8-0.2-0.8-1.3-1.3
Condit. Reinf. active minus inactive responses2.32.54.2-0.5-1.91.31.90.61.62.01.1-2.02.01.01.61.81.7
Condit. Reinf. active-inactive response ratio1.11.22.8-0.6-1.70.91.20.31.11.30.7-1.31.40.81.01.21.1
Condit. Reinf. active responses2.93.65.8-0.1-2.01.82.40.62.02.21.6-2.32.40.72.12.22.2
Condit. Reinf. inactive responses1.01.22.21.2-0.31.21.3-0.21.01.11.4-1.11.0-0.71.51.31.2
Incentive salience index mean1.82.24.0-0.4-1.91.11.70.31.51.61.3-1.92.00.61.61.61.6
Condit. Reinf. lever presses0.20.31.1-0.3-1.00.20.60.20.50.20.5-0.81.0-0.00.60.60.5
Time in familiar zone, hab. session 11.21.12.6-0.3-1.01.61.00.71.41.50.5-1.01.10.70.80.91.2
Time in novel zone, hab. session 11.61.63.4-0.11.2-1.8-1.3-0.2-1.7-1.6-1.21.3-1.4-0.3-1.4-1.2-1.5
Total zone transitions, hab. session 10.10.10.50.40.20.60.60.3-0.00.70.1-0.20.10.00.30.30.2
Total locomotion distance, hab. session 10.20.21.10.40.40.60.60.40.21.00.4-0.40.30.10.60.50.4
Locomotion velocity, hab. session 10.40.61.70.60.11.00.90.20.61.30.8-0.70.6-0.01.00.80.7
Time in familiar zone, hab. session 22.02.14.7-0.5-2.21.91.80.41.61.60.9-1.71.80.61.21.51.4
Time in novel zone, hab. session 22.42.45.80.92.4-1.7-1.9-0.5-1.5-1.6-0.91.8-2.0-0.9-1.2-1.5-1.5
Total zone transitions, hab. session 20.10.10.5-0.0-0.30.50.70.40.00.60.1-0.30.20.10.20.30.2
Total locomotion distance, hab. session 20.40.51.60.20.31.00.91.00.51.30.1-0.50.40.40.40.80.7
Locomotion velocity, hab. session 20.30.41.50.50.41.00.90.70.41.20.3-0.50.30.10.60.70.7
Novel to familiar place preference ratio0.10.10.30.30.00.30.4-0.00.30.10.5-0.40.4-0.40.40.50.5
Novelty place preference0.00.00.10.20.00.10.3-0.10.1-0.20.3-0.20.2-0.30.20.20.3
Time in novel zone, NPP test0.00.00.10.2-0.0-0.10.1-0.2-0.0-0.30.3-0.10.1-0.40.10.00.1
Total zone transitions, NPP test0.20.31.61.30.70.00.5-0.4-0.50.50.60.1-0.3-0.80.60.1-0.1
Total locomotion distance, NPP test0.20.30.80.70.40.80.60.40.40.90.5-0.30.2-0.10.70.50.4
Locomotion velocity, NPP test0.30.41.00.80.90.70.70.70.21.00.3-0.30.1-0.00.60.70.6
Pavlov. Cond. lever latency1.01.22.6-0.01.4-0.6-1.40.2-0.9-0.9-1.31.5-1.60.1-1.5-1.2-1.0
Pavlov. Cond. magazine entry latency2.33.05.50.1-2.01.52.10.11.81.71.7-2.32.30.02.12.11.9
Pavlov. Cond. change in total contacts2.02.24.3-1.0-1.80.91.90.51.31.50.9-2.02.11.01.31.81.6
Pavlov. Cond. index score2.02.64.80.1-1.91.22.1-0.21.51.31.7-2.12.2-0.12.01.91.7
Pavlov. Cond. latency score1.72.24.10.1-1.91.12.0-0.31.21.21.7-1.92.0-0.11.91.71.5
Pavlov. Cond. lever contacts1.01.22.7-0.7-1.60.61.30.31.00.90.8-1.51.60.51.11.21.1
Pavlov. Cond. magazine entry number1.72.24.10.21.7-1.0-1.8-0.0-1.4-1.3-1.52.0-2.0-0.2-1.8-1.9-1.6
Pavlov. Cond. intertrial magazine entries1.31.53.80.9-0.11.41.90.51.02.01.0-1.21.00.21.31.41.5
Pavlov. Cond. lever-magazine prob. diff.1.72.14.10.1-1.71.01.9-0.21.31.21.6-1.92.0-0.11.91.71.5
Pavlov. Cond. response bias1.82.24.4-0.0-1.70.91.7-0.11.41.31.6-2.02.10.01.91.81.6
Bone: apparent density0.50.92.31.2-0.00.40.4-1.00.90.51.5-0.80.7-1.01.51.01.0
Bone surface3.46.114.02.1-1.92.41.9-1.72.71.93.7-2.42.4-1.73.72.32.4
Bone volume2.74.510.51.9-1.31.91.8-1.32.31.73.2-2.12.1-1.43.22.22.2
Bone: connectivity density1.11.74.11.4-0.71.00.8-1.01.41.01.9-1.21.2-1.22.01.21.2
Bone: cortical apparent density3.54.68.90.23.0-2.6-1.9-0.0-2.8-2.0-2.22.4-2.6-0.4-2.6-2.0-2.3
Bone: cortical area0.71.12.61.40.20.51.4-0.20.40.91.6-1.00.8-1.01.51.21.0
Bone: cortical porosity4.24.59.6-1.0-3.11.61.90.12.51.82.0-2.73.00.82.32.22.2
Bone: cortical porosity2.12.34.3-0.0-2.01.01.5-0.61.51.31.9-1.92.1-0.02.01.61.4
Bone: cortical thickness4.67.716.90.94.1-3.9-2.2-0.4-3.9-2.6-2.13.0-3.3-1.2-2.7-2.5-2.9
Bone: cortical thickness4.04.78.6-0.12.4-2.9-2.0-0.1-2.9-2.3-2.12.4-2.4-0.3-2.4-2.3-2.6
Bone: cortical tissue density3.44.48.1-0.02.8-2.5-1.90.1-2.7-1.9-2.22.4-2.5-0.2-2.6-2.0-2.2
Bone: elastic displacement1.92.14.30.11.4-2.1-1.6-1.1-1.9-1.5-0.91.7-1.6-0.5-1.2-1.7-1.7
Bone: elastic work0.20.31.0-0.11.0-0.8-0.5-0.1-0.6-0.5-0.50.4-0.5-0.0-0.5-0.3-0.4
Bone: endosteal estimation11.524.938.50.3-5.76.15.20.46.24.95.1-5.86.00.85.95.35.5
Bone: endosteal perimeter13.327.343.51.5-5.46.25.6-0.36.25.16.0-6.06.0-0.46.65.65.7
Bone: final force0.71.24.22.10.20.40.6-1.40.20.21.7-0.30.2-1.91.50.40.3
Bone: final moment0.71.13.71.90.20.30.6-1.40.20.11.7-0.30.3-1.81.50.50.4
Bone: marrow area11.224.137.50.2-5.76.05.10.46.14.85.0-5.75.90.85.85.25.4
Bone: maximum diameter3.66.614.52.0-1.92.52.7-1.12.62.33.8-2.62.6-1.53.72.62.6
Bone: maximum force1.12.06.22.50.31.11.4-0.80.81.02.1-0.90.7-1.82.11.21.1
Bone: maximum moment1.01.84.92.20.21.11.3-0.80.81.02.0-1.00.8-1.62.01.21.1
Bone: minimum diameter9.317.225.81.1-3.64.74.70.44.74.44.5-4.94.8-0.05.14.84.9
Bone: periosteal estimation6.413.222.01.2-3.34.04.1-0.04.13.64.3-4.24.2-0.34.74.14.1
Bone: periosteal perimeter3.96.415.22.0-2.22.22.6-1.42.32.03.9-2.62.6-1.73.72.52.5
Bone: post-yield work1.72.34.00.7-1.52.01.6-0.11.81.51.9-1.61.7-0.42.01.51.6
Bone: stiffness1.42.26.62.6-0.41.31.4-1.30.70.62.4-0.80.7-2.12.10.80.8
Bone: tissue strength1.71.63.21.81.3-1.0-1.0-1.5-1.3-1.10.41.4-1.4-1.8-0.2-1.3-1.3
Bone: trabecular number1.32.05.31.8-0.50.91.0-1.31.31.12.3-1.21.2-1.42.31.31.3
Bone: trabecular spacing0.30.41.6-1.2-0.40.0-0.10.8-0.3-0.4-0.90.2-0.10.9-1.0-0.3-0.4
Bone: trabecular thickness0.91.12.30.90.20.60.7-0.11.21.21.4-1.10.9-0.51.51.41.5
Bone: trabecular tissue density1.92.76.92.42.6-1.4-1.2-1.1-1.8-0.90.11.8-2.1-2.1-0.5-1.4-1.4
Breakpoint value in progressive ratio session1.01.13.1-0.7-1.80.81.30.21.00.80.9-1.31.40.70.91.20.9
Distance traveled before self-admin1.11.14.21.4-0.0-0.8-0.8-2.1-0.7-0.91.10.7-0.7-1.90.3-0.7-0.8
Distance traveled after self-admin0.50.52.70.5-1.1-0.40.0-1.6-0.2-0.51.10.10.1-0.90.7-0.4-0.4
Delta time in closed arm before/after self-admin0.20.21.10.3-0.30.0-0.5-1.00.1-0.40.70.2-0.0-0.70.3-0.4-0.3
Delta time in open arm before/after self-admin0.30.31.0-0.30.6-0.20.10.9-0.40.0-1.00.1-0.40.5-0.80.2-0.2
Diff in mean of infusions in LGA sessions0.91.02.0-0.90.7-1.0-0.70.8-1.1-1.1-1.40.9-0.90.8-1.3-0.9-0.9
Extinction: sum of active levers before priming0.60.61.3-0.1-0.60.91.20.40.60.60.5-1.00.90.30.61.10.8
Active lever presses in extinction session 61.81.82.8-0.9-1.31.21.51.11.41.70.6-1.61.61.00.91.61.6
Delta distance traveled before/after self-admin0.30.30.9-0.9-0.2-0.60.10.4-0.6-0.5-0.90.20.00.8-0.5-0.4-0.5
Delta ambulatory time before/after self-admin0.10.10.3-0.4-0.30.00.50.30.10.1-0.2-0.30.40.50.20.10.1
Time in closed arm before self-admin1.11.22.5-0.50.6-1.4-1.0-0.2-1.5-1.3-1.41.1-1.00.1-1.3-1.2-1.6
Time in closed arm after self-admin0.90.92.30.0-0.2-0.7-1.2-1.5-0.8-1.5-0.11.0-0.7-0.8-0.6-1.4-1.3
Time in open arm before self-admin0.50.51.30.00.4-0.8-1.1-0.6-0.6-0.9-0.00.9-0.6-0.3-0.4-1.1-0.7
Time in open arm after self-admin0.30.31.1-0.20.20.40.51.10.40.8-0.1-0.40.20.60.00.70.7
Sum of active levers in priming session hrs 5-60.10.10.2-0.3-0.5-0.20.30.2-0.4-0.2-0.2-0.1-0.00.3-0.30.1-0.2
Time to tail flick, vehicle, before self-admin1.21.24.11.70.4-0.6-1.2-2.0-0.2-0.71.20.7-0.7-1.90.6-0.8-0.5
Time to tail flick, vehicle, after self-admin0.90.92.41.30.10.90.7-0.90.90.91.5-0.70.4-0.91.41.11.0
Time to tail flick, test, before self-admin0.60.61.5-1.00.1-0.5-1.20.3-0.2-0.7-1.20.7-0.60.6-1.1-1.0-0.6
Time to tail flick, test, after self-admin0.30.30.70.80.8-0.7-0.5-0.4-0.5-0.4-0.00.5-0.5-0.8-0.1-0.4-0.4
Delta time to tail flick, vehicle, before/after SA2.02.03.5-0.6-0.71.81.61.31.61.80.4-1.61.41.10.91.91.7
Delta time to tail flick, test, before/after SA0.50.42.11.50.2-0.00.3-1.0-0.2-0.00.9-0.0-0.1-1.30.70.2-0.0
Ambulatory time before self-admin0.80.83.71.3-0.3-0.4-0.5-1.9-0.4-0.61.10.4-0.4-1.70.5-0.5-0.6
Ambulatory time after self-admin0.30.31.40.3-0.8-0.20.3-1.2-0.0-0.11.0-0.20.4-0.50.8-0.0-0.1
Total heroin consumption0.50.61.80.5-1.10.10.7-1.00.40.41.4-0.70.8-0.51.20.50.5
Area under the delay curve0.40.42.31.50.8-0.10.1-0.6-0.00.20.8-0.0-0.0-1.10.80.20.3
Delay disc. indifference point, 0s delay0.50.61.21.00.9-0.7-0.7-0.8-0.7-0.8-0.00.8-0.9-1.1-0.1-0.7-0.6
Delay disc. indifference point, 16s delay0.40.41.61.30.6-0.10.5-0.10.10.60.8-0.40.2-0.70.90.60.6
Delay disc. indifference point, 2s delay1.82.07.82.80.50.70.4-1.80.60.52.1-0.30.2-2.41.90.60.8
Delay disc. indifference point, 24s delay1.41.42.51.20.21.11.60.40.91.61.2-1.21.0-0.31.41.61.4
Delay disc. indifference point, 4s delay0.91.01.61.00.9-1.3-1.1-1.1-0.9-1.0-0.01.1-1.0-1.3-0.2-1.1-0.9
Delay disc. indifference point, 8s delay0.50.52.01.31.4-0.7-0.5-0.5-0.6-0.30.20.6-0.6-1.00.1-0.4-0.2
Delay discount exponential model param0.50.52.2-1.5-0.5-0.2-0.30.5-0.3-0.5-1.00.3-0.21.1-1.0-0.4-0.5
Delay discount hyperbolic model param0.50.62.7-1.7-0.7-0.1-0.20.7-0.1-0.3-1.00.1-0.01.3-1.0-0.3-0.4
Fecal boli incidents, locomotor time 10.10.10.30.2-0.20.20.1-0.30.20.20.5-0.1-0.0-0.20.30.10.3
Change in fecal boli incidents, locomotor task0.40.41.90.41.4-0.5-0.40.8-0.5-0.4-0.90.5-0.4-0.2-0.8-0.3-0.3
Time >=10cm from walls, locomotor time 12.22.23.80.90.4-1.5-1.4-1.9-1.6-1.9-0.31.7-1.6-1.6-0.8-1.9-1.8
Bouts of movement, locomotor time 10.91.03.0-1.11.1-0.6-0.81.6-0.6-0.4-1.70.6-0.71.2-1.4-0.5-0.5
Total resting periods, locomotor time 11.01.13.1-1.01.3-0.7-1.01.6-0.6-0.5-1.70.8-0.91.1-1.4-0.7-0.5
Rest time, locomotor task time 10.20.20.7-0.20.5-0.5-0.80.1-0.2-0.5-0.60.4-0.30.0-0.5-0.3-0.3
Distance moved, locomotor task time 10.30.30.6-0.1-0.40.70.80.60.60.70.5-0.60.70.30.60.50.7
Vertical activity count, locomotor time 10.10.10.40.4-0.30.30.4-0.20.30.20.6-0.30.4-0.20.60.20.3
Time >=10cm from walls, locomotor time 20.30.30.9-0.5-0.5-0.5-1.0-0.1-0.2-0.9-0.40.4-0.3-0.1-0.6-0.6-0.7
Bouts of movement, locomotor time 20.70.72.5-1.00.7-0.7-0.31.5-0.5-0.1-1.60.4-0.61.2-1.1-0.2-0.3
Total resting periods, locomotor time 20.80.92.8-0.90.9-1.0-0.51.2-0.8-0.4-1.70.7-0.91.0-1.3-0.5-0.6
Rest time, locomotor task time 22.52.94.30.71.8-2.0-2.1-1.2-1.8-1.9-1.41.9-2.1-1.3-1.5-1.8-1.8
Distance moved, locomotor task time 20.60.72.3-1.5-0.90.60.41.40.70.4-0.2-0.60.81.5-0.00.20.5
Vertical activity count, locomotor time 22.52.85.8-2.0-1.71.51.61.81.71.60.3-1.92.02.40.71.61.5
Weight adjusted by age0.40.40.80.90.7-0.7-0.4-0.7-0.7-0.7-0.10.7-0.8-0.9-0.1-0.6-0.5
Seeking ratio, delayed vs. immediate footshock0.40.51.8-1.00.00.30.51.30.10.4-1.0-0.30.21.3-0.50.30.3
Locomotion in novel chamber0.60.83.01.3-0.2-0.3-0.5-1.7-0.1-0.41.20.4-0.3-1.60.8-0.8-0.3
Locomotion in novel chamber post-restriction2.32.77.02.2-0.81.81.2-1.41.51.12.6-1.21.0-1.82.41.31.4
Progressive ratio0.50.52.11.30.10.2-0.4-1.30.1-0.31.00.3-0.4-1.40.6-0.3-0.1
Food seeking constrained by brief footshock3.64.37.7-1.1-2.82.82.10.92.62.21.3-2.42.61.11.72.12.3
Seeking ratio, punishment vs. effort1.72.13.2-1.6-1.61.31.61.61.31.60.0-1.61.81.80.61.31.4
Run reversals in cocaine runway, females1.91.96.0-1.71.4-0.9-1.42.0-0.6-0.5-2.40.7-0.81.9-1.9-0.4-0.7
Run reversals in cocaine runway, males0.30.20.60.50.5-0.6-0.5-0.6-0.4-0.40.20.5-0.6-0.8-0.0-0.5-0.3
Latency to leave start box in cocaine runway0.30.30.6-0.20.2-0.8-0.6-0.4-0.7-0.7-0.50.7-0.7-0.1-0.5-0.7-0.7
Latency to leave start box in cocaine runway, F1.01.12.30.50.6-1.5-0.9-1.0-1.4-1.2-0.41.1-1.1-0.8-0.6-1.3-1.2
Latency to leave start box in cocaine runway, M0.30.31.1-1.0-0.40.5-0.20.50.40.1-0.7-0.20.20.9-0.50.30.1
Cd content in liver1.61.83.0-0.80.7-1.2-1.7-0.0-1.3-1.2-1.61.7-1.70.3-1.7-1.7-1.4
Co content in liver0.50.53.4-1.8-1.0-0.2-0.20.3-0.10.2-0.80.10.01.3-0.8-0.4-0.1
Cu content in liver0.30.41.1-0.8-0.10.30.30.90.60.7-0.3-0.60.61.0-0.10.70.8
Fe content in liver0.10.10.3-0.1-0.1-0.50.0-0.0-0.5-0.5-0.20.3-0.20.1-0.1-0.4-0.4
K content in liver2.02.06.21.5-1.31.11.1-1.71.10.62.5-1.01.0-1.72.10.91.1
Mg content in liver0.30.40.90.4-0.70.60.4-0.60.70.10.9-0.50.5-0.60.70.50.6
Mn content in liver1.11.24.42.00.1-0.10.1-2.1-0.1-0.41.80.2-0.2-1.91.3-0.2-0.2
Na content in liver1.21.33.80.6-1.60.41.4-1.40.50.22.0-1.11.2-1.01.70.90.7
Rb content in liver1.72.14.20.80.8-1.5-1.5-1.6-1.6-1.6-0.21.8-1.7-1.3-0.9-2.0-1.7
Se content in liver0.70.81.81.00.7-1.0-0.5-1.3-1.1-0.50.41.0-1.0-1.3-0.2-0.9-0.8
Sr content in liver0.10.10.40.40.10.10.2-0.60.10.60.6-0.20.2-0.30.50.30.2
Zn content in liver1.21.46.11.70.0-0.20.3-2.5-0.20.52.0-0.00.0-1.91.30.20.2