Hub : Genes

Polm

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000013647 0.02 0.02 3.5e-03 0 -0 -0 -0 3.3e-01 6.9e-01 3.7e-01 3.8e-01
2 BLA gene expression ENSRNOG00000013647 0.06 0.05 5.4e-03 0.02 0.03 0.02 0.02 1.8e-02 1.2e-02 3.5e-02 2.9e-02
3 Brain gene expression ENSRNOG00000013647 0.52 0.16 0.0e+00 0.45 0.46 0.46 0.46 2.6e-45 6.1e-47 1.5e-47 6.2e-47
4 Brain intron excision ratio chr14:80715168:80716216 0.04 0.03 4.0e-04 0.03 0.02 0.02 0.01 1.3e-03 3.2e-03 1.1e-02 1.3e-02
5 Brain intron excision ratio chr14:80715168:80716383 0.05 0.04 1.7e-04 0.02 0.04 0.03 0.02 2.8e-03 3.4e-04 8.6e-04 3.3e-03
6 IL gene expression ENSRNOG00000013647 0.91 0.09 4.5e-09 0.21 0.18 0.31 0.29 1.1e-05 3.4e-05 3.0e-08 1.2e-07
7 LHb gene expression ENSRNOG00000013647 0.42 0.17 1.8e-08 0.22 0.26 0.26 0.26 4.5e-06 8.5e-07 8.5e-07 8.3e-07
8 Liver gene expression ENSRNOG00000013647 0.04 0.03 3.5e-03 0.02 0.01 0.01 0.01 1.2e-03 2.7e-02 4.5e-02 2.3e-02
9 Liver intron excision ratio chr14:80715168:80716383 0.02 0.02 8.8e-03 0.01 0.01 0 0 6.4e-02 2.5e-02 1.6e-01 1.4e-01
10 NAcc gene expression ENSRNOG00000013647 0.16 0.1 5.1e-09 0.08 0.1 0.09 0.08 1.0e-06 3.0e-08 6.7e-07 7.5e-07
11 OFC gene expression ENSRNOG00000013647 0.24 0.15 1.6e-04 0.07 0.13 0.12 0.13 8.3e-03 5.1e-04 7.8e-04 4.6e-04
12 PL gene expression ENSRNOG00000013647 0.42 0.15 0.0e+00 0.41 0.44 0.44 0.43 1.0e-33 6.2e-37 6.9e-36 1.5e-35

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.00.00.1-0.3-0.2-0.3-0.20.00.0-0.1-0.20.2-0.3-0.0-0.1
BMI without tail0.10.22.3-0.1-0.0-0.1-0.0-0.11.50.20.1-0.0-0.10.20.1
Body weight1.35.67.3-2.3-2.5-2.7-2.31.6-1.7-2.2-2.62.6-2.7-2.3-2.4
Epididymis fat weight0.30.70.90.90.90.90.9-0.9-0.50.90.9-0.90.80.80.9
Glucose13.821.139.3-5.1-4.4-4.8-5.06.3-3.7-5.3-1.23.9-3.4-4.8-5.1
Heart weight0.40.63.20.40.60.50.40.1-1.80.40.9-0.80.80.60.5
Left kidney weight0.10.20.90.50.20.20.4-1.00.20.4-0.90.1-0.10.40.4
Right kidney weight0.82.44.61.71.51.51.6-2.21.71.80.2-1.21.11.71.7
Tail length1.23.55.0-2.0-2.0-2.2-2.01.30.2-1.8-2.12.1-2.1-1.9-1.9
Length with tail1.86.68.7-2.5-2.7-2.9-2.51.7-1.4-2.5-3.02.9-2.9-2.6-2.6
Length without tail1.22.64.1-1.4-1.6-1.7-1.41.1-2.0-1.6-1.81.7-1.6-1.6-1.6
Liver weight, left2.74.310.92.11.91.92.0-2.33.32.11.4-1.71.62.02.0
Liver weight, right4.47.412.93.02.52.73.0-3.63.53.00.7-1.91.92.72.8
Parametrial fat weight1.53.03.9-1.8-1.9-2.0-1.91.70.3-1.9-1.31.9-1.7-1.7-1.9
Retroperitoneal fat weight0.00.10.2-0.0-0.2-0.1-0.0-0.40.50.1-0.50.3-0.4-0.0-0.0
Intraocular pressure0.50.71.8-0.7-0.7-0.8-0.70.8-1.4-0.8-1.10.6-0.6-0.7-0.7
Extensor digitorum longus weight3.012.214.3-3.7-3.6-3.8-3.63.2-2.8-3.7-2.73.6-3.5-3.7-3.7
Soleus weight0.71.94.9-1.1-1.4-1.5-1.10.4-1.2-1.1-2.21.7-1.7-1.2-1.3
Tibialis anterior weight1.13.75.1-2.1-2.0-2.3-2.12.0-1.4-2.0-1.31.9-1.8-2.0-2.1
Tibia length0.20.51.60.60.3-0.00.6-1.11.30.7-0.9-0.10.00.50.5
Number of licking bursts3.13.76.2-1.8-1.9-2.0-1.81.6-2.5-1.9-1.91.9-1.8-2.0-1.9
Food consumed during 24 hour testing period2.12.54.4-1.7-1.5-1.6-1.71.9-2.1-1.7-0.51.3-1.2-1.7-1.7
Times rat made contact with spout0.80.94.3-0.20.30.1-0.21.4-1.8-0.32.1-0.70.9-0.1-0.2
Mean time between licks in bursts0.40.61.4-0.7-0.6-0.9-0.71.2-1.1-0.8-0.30.4-0.3-0.6-0.8
Mean num. licks in bursts2.42.98.41.41.71.71.4-0.51.11.42.9-2.02.01.61.5
Std. dev. time between licks in bursts0.10.11.0-0.1-0.1-0.2-0.20.3-1.0-0.1-0.30.0-0.0-0.0-0.1
Water consumed over 24 hours1.41.73.6-1.3-1.1-1.2-1.31.8-1.9-1.40.00.9-0.8-1.3-1.4
Indifference point 0 sec2.03.25.4-2.1-1.7-2.0-2.02.3-2.0-1.8-0.71.4-1.4-1.7-1.9
Indifference point AUC0.20.20.9-0.4-0.3-0.4-0.40.7-0.9-0.50.20.2-0.1-0.4-0.4
Indifference point function ln k0.00.10.20.1-0.10.00.1-0.50.40.1-0.40.3-0.30.00.1
Indifference point function log k0.00.10.20.1-0.10.00.1-0.50.40.1-0.40.3-0.30.00.1
Delay discounting total patch changes 0 sec2.23.56.1-2.2-1.8-2.1-2.12.5-2.1-1.9-0.61.4-1.4-1.8-2.0
Delay discounting total patch changes 12 sec1.21.63.4-1.4-1.2-1.5-1.41.8-1.4-1.3-0.00.9-0.9-1.2-1.4
Delay discounting total patch changes 18 sec2.12.75.7-1.8-1.5-1.9-1.82.4-2.0-1.7-0.51.1-1.1-1.5-1.7
Delay discounting total patch changes 24 sec0.60.82.40.50.90.60.50.30.00.71.6-1.31.21.00.7
Delay discounting total patch changes 6 sec2.43.65.8-2.2-1.8-2.1-2.12.4-2.2-2.0-0.61.5-1.5-1.9-2.0
Delay discounting time to switch 0 sec0.50.81.40.90.90.80.9-1.11.21.00.4-0.80.70.90.9
Delay discounting water rate 0 sec2.33.65.7-2.0-1.8-2.0-2.02.2-2.4-2.0-1.21.6-1.6-1.8-1.9
Delay discounting water rate 12 sec0.20.31.6-0.5-0.5-0.5-0.40.4-1.3-0.4-0.60.4-0.4-0.4-0.4
Delay discounting water rate 18 sec0.30.42.00.30.00.10.3-1.11.40.4-1.00.3-0.40.30.3
Delay discounting water rate 24 sec0.10.10.2-0.3-0.3-0.3-0.30.20.2-0.3-0.50.3-0.3-0.1-0.2
Delay discounting water rate 6 sec0.30.51.6-0.5-0.8-0.7-0.40.20.2-0.6-1.30.9-0.9-0.7-0.6
Locomotor activity0.40.62.1-0.9-0.6-0.9-0.81.5-0.6-0.90.00.4-0.3-0.8-0.9
Locomotor testing distance0.30.52.7-0.5-0.5-0.6-0.40.3-1.6-0.3-0.80.5-0.5-0.4-0.5
Locomotor testing rearing2.03.27.6-1.7-1.6-1.9-1.72.0-2.8-1.7-1.21.5-1.4-1.7-1.8
Light reinforcement 10.20.41.6-0.4-0.5-0.4-0.40.1-1.3-0.4-1.00.6-0.6-0.4-0.4
Light reinforcement 20.30.42.00.1-0.20.00.0-0.91.00.1-1.40.6-0.60.00.0
Reaction time number correct0.10.20.9-0.4-0.2-0.2-0.40.7-0.9-0.40.20.1-0.1-0.2-0.3
Reaction time mean minus median1.72.24.41.41.71.61.3-0.60.11.32.1-1.91.91.41.4
Reaction time mean minus median AUC1.51.93.31.31.51.41.2-0.6-0.71.21.8-1.71.81.31.3
Reaction time num false alarms0.81.13.4-0.9-1.0-0.9-0.80.3-1.8-0.7-1.21.0-1.2-0.8-0.8
Reaction time num false alarms AUC0.70.92.5-0.8-1.0-0.8-0.80.0-1.6-0.6-1.31.0-1.2-0.8-0.7
Reaction time trials correct on left0.10.20.9-0.4-0.2-0.2-0.40.7-0.9-0.40.20.1-0.1-0.2-0.3
Reaction time trials on left0.10.10.8-0.3-0.2-0.1-0.40.6-0.9-0.30.20.0-0.0-0.2-0.3
Reaction time mean0.91.22.70.91.11.10.9-0.91.71.10.9-1.11.01.11.1
Reaction time mean AUC1.41.93.51.31.41.41.2-1.31.91.41.0-1.31.31.41.4
Median of all reaction times0.70.95.40.70.70.80.6-0.92.30.80.4-0.60.60.80.8
Reaction time omissions0.91.21.51.01.11.21.0-1.01.01.21.1-1.21.11.21.2
Reaction time false alarm rate0.50.71.9-0.6-0.8-0.7-0.5-0.3-1.1-0.4-1.40.9-1.2-0.7-0.5
Reaction time premature initiation rate2.43.24.32.01.92.02.0-2.10.81.91.3-1.71.71.82.0
Reaction time premature initiations1.11.62.21.41.41.51.3-1.20.11.21.2-1.31.31.21.4
Std. dev. reaction times1.31.82.81.21.51.41.2-0.80.41.31.7-1.61.61.41.3
Reaction time trials completed0.10.10.8-0.3-0.2-0.1-0.40.6-0.9-0.30.20.0-0.0-0.2-0.3
Reaction time trials AUC0.10.20.9-0.4-0.3-0.3-0.50.7-0.9-0.40.10.2-0.1-0.3-0.4
Social response proportion1.51.62.3-1.2-1.4-1.3-1.21.1-0.6-1.5-0.81.5-1.4-1.4-1.4
Social responses2.43.13.9-1.9-1.9-1.9-1.81.8-1.0-2.0-1.11.8-1.8-1.9-1.9
Social time0.30.40.6-0.7-0.8-0.7-0.70.7-0.1-0.7-0.30.7-0.8-0.7-0.7
Conditioned locomotion0.70.82.71.00.70.91.0-1.70.51.1-0.3-0.50.30.91.1
Cocaine response after cond. corrected1.61.75.1-1.1-1.2-1.2-1.11.1-2.3-1.2-1.41.2-1.1-1.3-1.2
Cocaine response after cond. not corrected1.71.95.2-1.1-1.2-1.3-1.11.0-2.3-1.2-1.51.3-1.2-1.3-1.3
Cocaine response before conditioning0.30.40.60.70.60.60.7-0.80.70.70.2-0.50.50.70.7
Saline control response0.30.41.40.50.60.60.5-0.3-1.20.50.5-0.80.70.60.6
Condit. Reinf. active minus inactive responses0.30.40.50.60.60.70.7-0.60.50.60.5-0.60.60.70.7
Condit. Reinf. active-inactive response ratio0.00.00.3-0.1-0.1-0.1-0.1-0.20.10.0-0.50.2-0.30.0-0.0
Condit. Reinf. active responses0.50.70.90.90.91.00.9-0.80.80.80.7-0.80.80.80.9
Condit. Reinf. inactive responses1.01.22.11.11.21.21.2-0.60.70.91.5-1.21.31.01.0
Condit. Reinf. lever presses0.30.40.60.70.70.80.7-0.6-0.10.60.4-0.70.60.60.7
Condit. Reinf. lever reinforcers received0.40.50.70.80.70.90.8-0.70.60.70.6-0.70.70.70.8
Pavlov. Cond. lever latency3.24.47.1-2.0-2.3-2.3-2.01.2-0.9-1.9-2.72.5-2.5-2.1-2.1
Pavlov. Cond. magazine entry latency0.10.21.70.10.10.30.10.1-1.3-0.10.1-0.20.2-0.10.1
Pavlov. Cond. change in total contacts0.30.40.50.60.70.70.7-0.40.70.50.6-0.70.70.60.6
Pavlov. Cond. index score1.21.52.31.31.41.51.3-0.80.31.11.4-1.41.51.21.3
Pavlov. Cond. latency score1.21.52.21.21.31.51.2-0.90.31.11.3-1.41.41.21.3
Pavlov. Cond. lever contacts2.83.95.61.92.22.21.9-1.20.71.82.2-2.42.42.02.0
Pavlov. Cond. magazine entry number0.10.20.80.0-0.2-0.30.0-0.50.70.1-0.90.4-0.50.0-0.0
Pavlov. Cond. intertrial magazine entries0.00.10.3-0.1-0.2-0.3-0.2-0.0-0.5-0.0-0.30.2-0.3-0.1-0.1
Pavlov. Cond. lever-magazine prob. diff.1.21.52.21.31.41.51.3-0.80.21.11.4-1.41.41.21.3
Pavlov. Cond. response bias1.31.73.11.21.51.51.2-0.50.21.11.8-1.71.71.31.3
Conditioned reinforcement - actives0.00.00.10.0-0.00.00.0-0.10.30.0-0.10.0-0.10.10.1
Conditioned reinforcement - inactives0.10.10.7-0.2-0.1-0.1-0.20.10.8-0.20.10.2-0.1-0.2-0.1
Conditioned locomotion0.10.10.4-0.1-0.3-0.2-0.1-0.10.1-0.1-0.70.3-0.50.1-0.1
Intermittent access intake day 1-15 change0.40.41.4-0.6-0.6-0.7-0.71.20.0-0.6-0.10.3-0.3-0.5-0.7
Intermittent access intake escalation0.20.21.0-0.5-0.4-0.5-0.51.00.4-0.50.10.1-0.1-0.4-0.5
Intermittent access intake escalation 20.20.21.1-0.4-0.2-0.5-0.41.10.6-0.40.4-0.10.1-0.3-0.4
Intermitt. access day 1 inactive lever presses0.50.61.60.80.70.90.8-1.30.80.70.0-0.40.40.80.9
Intermitt. access day 15 inactive lever presses1.21.31.7-1.3-1.2-1.3-1.31.3-0.5-1.2-0.91.1-1.2-1.2-1.2
Intermitt. access escalation Index0.30.30.9-0.6-0.4-0.6-0.61.0-0.6-0.50.20.2-0.2-0.4-0.5
Intermittent access day 1 total infusions0.40.41.50.60.60.70.6-0.81.20.60.3-0.40.40.60.6
Intermittent access day 15 total infusions0.10.20.7-0.3-0.3-0.3-0.30.50.9-0.3-0.10.2-0.2-0.3-0.3
Intermittent access terminal intake (last 3 days)0.10.10.8-0.2-0.1-0.3-0.20.70.9-0.20.3-0.10.1-0.0-0.2
Intermittent access total infusions0.10.11.3-0.1-0.0-0.0-0.10.11.2-0.10.10.00.00.0-0.1
Intermittent access day 1 locomotion1.41.44.21.11.01.31.1-1.52.11.10.5-0.70.71.21.2
Intermittent access day 15 total locomotion0.30.42.5-0.3-0.5-0.3-0.30.01.6-0.3-0.50.6-0.6-0.3-0.3
Intermittent access total locomotion0.40.42.7-0.4-0.5-0.3-0.4-0.11.6-0.4-0.70.7-0.7-0.3-0.3
Intermittent access standard deviation1.51.72.91.11.31.21.0-0.41.71.11.6-1.51.51.31.1
Cocaine induced anxiety3.03.54.6-2.0-2.0-2.1-2.01.8-0.9-1.9-1.51.9-1.9-2.0-2.0
Post-drug Anxiety0.91.01.3-1.1-1.0-1.1-1.11.1-0.2-1.2-0.61.0-0.9-1.2-1.1
Baseline Anxiety0.30.30.50.70.60.70.6-0.50.10.40.4-0.50.60.50.6
Lifetime Intake0.10.10.9-0.1-0.1-0.1-0.10.11.0-0.1-0.00.1-0.10.0-0.1
Incentive Sensitization - Responses0.00.00.40.00.0-0.10.00.30.6-0.00.2-0.10.20.0-0.1
Incentive Sensitization - Breakpoint0.10.10.40.10.10.00.10.30.60.00.3-0.20.30.10.0
Progressive ratio test 1 active lever presses0.10.11.70.00.00.10.0-0.11.30.00.00.0-0.00.10.1
Progressive ratio test 1 breakpoint0.40.42.40.40.40.50.4-0.51.60.40.3-0.30.30.60.5
Progressive ratio test 1 inactive lever presses2.42.64.1-1.6-1.8-1.6-1.50.7-0.7-1.5-2.02.0-2.0-1.6-1.6
Progressive ratio test 2 active lever presses0.10.11.60.10.10.00.00.11.30.00.2-0.10.20.10.0
Progressive ratio test 2 breakpoint0.10.10.7-0.0-0.0-0.1-0.10.30.80.00.2-0.10.10.0-0.1
Progressive ratio test 2 inactive lever presses0.50.60.9-0.7-0.9-0.7-0.70.50.7-0.8-1.00.9-0.9-0.7-0.7
Total sessions with >9 infusions0.00.00.10.20.20.20.2-0.10.00.20.2-0.20.20.20.2
Short access day 1 total inactive lever presses2.93.34.4-1.8-2.0-2.0-1.81.2-0.8-1.7-2.12.1-2.1-1.9-1.8
Short access day 10 total inactive lever presses0.10.10.30.30.30.40.3-0.6-0.10.4-0.0-0.20.10.30.4
Short access day 1 total infusions0.40.40.80.80.60.80.7-0.90.40.70.2-0.50.40.70.7
Short access day 10 total infusions0.40.50.90.70.70.70.7-0.81.00.70.4-0.60.60.70.7
Short access total infusions0.50.50.60.80.70.80.7-0.70.70.80.6-0.70.70.80.7
Short access day 1 locomotion1.51.62.91.41.21.51.4-1.7-0.11.40.5-1.11.01.41.4
Short access day 10 total locomotion1.61.811.21.00.81.20.9-1.73.30.90.3-0.50.51.01.1
Short access total locomotion3.94.05.12.12.02.22.0-2.22.32.01.4-1.81.72.12.1
Compulsive drug intake2.02.02.31.51.51.51.5-1.3-0.01.51.3-1.51.51.51.5
One hour access (0.3 mA shock)0.40.44.50.20.20.20.2-0.32.10.20.1-0.10.20.30.2
One hour access (shock baseline)0.60.73.9-0.7-0.7-0.6-0.70.52.0-0.7-0.60.8-0.6-0.6-0.7
Number of responses in last shaping day0.10.11.10.1-0.1-0.10.1-0.4-1.10.2-0.50.1-0.20.20.1
Context. condit. distance diff. score2.83.44.81.82.02.01.7-1.50.12.01.7-2.22.02.12.0
Locomotion velocity, session 10.10.10.40.30.30.20.20.30.00.10.6-0.30.50.20.1
Locomotion distance, session 10.50.72.31.00.60.91.0-1.50.50.9-0.4-0.30.30.80.9
Locomotion velocity, session 20.30.32.0-0.10.10.1-0.20.9-1.4-0.30.8-0.30.4-0.1-0.2
Locomotion distance, session 20.91.32.71.21.01.31.2-1.21.61.10.8-1.00.91.21.2
Locomotion velocity, session 31.61.82.41.51.41.41.5-1.5-0.31.50.4-1.41.31.51.5
Locomotion distance, session 30.70.83.4-0.8-0.8-0.8-0.70.6-1.8-0.7-1.00.7-0.8-0.7-0.7
Stereotopy head waving bouts, day 30.50.60.90.70.80.90.8-0.90.70.80.4-0.70.60.80.9
Stereotopy head waving duration, day 32.02.43.51.51.61.71.5-1.41.91.61.2-1.51.51.61.6
Locomotion velocity, session 70.40.41.7-0.6-0.5-0.5-0.50.6-1.3-0.5-0.40.4-0.5-0.6-0.5
Locomotion distance, session 70.10.20.50.30.40.40.3-0.2-0.30.40.7-0.50.40.40.4
Stereotopy head waving bouts, day 70.60.71.20.81.01.00.8-0.5-0.00.80.2-1.01.10.90.9
Stereotopy head waving duration, day 70.20.31.70.20.20.40.2-0.4-1.30.3-0.9-0.20.20.30.3
Locomotion velocity, session 81.21.42.01.01.21.31.0-0.4-1.41.01.1-1.41.41.21.1
Locomotion distance, session 86.19.111.23.03.23.33.0-2.72.03.22.7-3.33.13.33.2
Degree of sensitization distance2.92.95.11.71.81.81.6-1.11.41.62.3-1.91.91.71.6
Degree of sensitization stereotypy0.00.00.4-0.1-0.0-0.1-0.10.1-0.3-0.1-0.70.00.1-0.0-0.1
Condit. Reinf. active minus inactive responses1.41.62.2-1.5-1.3-1.4-1.41.4-1.2-1.3-0.81.1-1.1-1.2-1.3
Condit. Reinf. active-inactive response ratio0.20.31.2-0.5-0.1-0.3-0.51.10.1-0.40.9-0.30.3-0.2-0.3
Condit. Reinf. active responses0.91.12.7-1.0-1.0-1.0-1.00.9-1.7-0.9-1.10.9-0.9-0.9-0.9
Condit. Reinf. inactive responses0.81.04.9-0.5-0.8-0.6-0.60.0-2.2-0.5-1.60.9-1.0-0.6-0.6
Incentive salience index mean2.02.42.9-1.7-1.6-1.6-1.61.3-1.3-1.5-1.61.5-1.6-1.5-1.5
Condit. Reinf. lever presses0.81.03.8-0.8-1.1-0.8-0.70.0-0.7-0.7-2.01.2-1.3-0.9-0.8
Time in familiar zone, hab. session 10.20.21.90.10.10.10.2-0.2-1.40.3-0.6-0.20.10.30.2
Time in novel zone, hab. session 10.30.31.2-0.5-0.3-0.3-0.30.61.1-0.50.60.3-0.2-0.6-0.5
Total zone transitions, hab. session 10.00.00.1-0.1-0.10.1-0.10.0-0.3-0.1-0.20.1-0.1-0.2-0.1
Total locomotion distance, hab. session 10.30.42.0-0.1-0.4-0.2-0.1-0.2-1.3-0.2-1.40.6-0.5-0.4-0.3
Locomotion velocity, hab. session 10.10.10.90.2-0.10.10.2-0.3-0.50.0-0.90.2-0.2-0.10.0
Time in familiar zone, hab. session 21.81.83.71.31.31.21.3-1.21.91.51.0-1.31.21.51.4
Time in novel zone, hab. session 22.42.43.3-1.6-1.5-1.5-1.61.8-1.7-1.8-0.41.4-1.3-1.8-1.7
Total zone transitions, hab. session 20.81.01.7-0.9-1.2-0.8-0.80.5-0.5-1.0-1.21.3-1.3-1.0-1.0
Total locomotion distance, hab. session 21.11.52.4-1.0-1.4-1.0-1.00.6-1.1-1.2-1.51.5-1.5-1.2-1.2
Locomotion velocity, hab. session 21.41.83.8-1.1-1.5-1.2-1.10.6-1.0-1.3-1.91.7-1.7-1.3-1.3
Novel to familiar place preference ratio0.30.30.9-0.5-0.4-0.3-0.50.90.3-0.70.30.4-0.1-0.6-0.6
Novelty place preference0.30.31.0-0.5-0.4-0.3-0.51.00.2-0.80.50.4-0.1-0.7-0.7
Time in novel zone, NPP test0.30.31.1-0.5-0.4-0.3-0.51.1-0.1-0.80.60.3-0.1-0.7-0.7
Total zone transitions, NPP test0.30.41.50.70.40.60.7-1.20.60.7-0.4-0.20.00.60.7
Total locomotion distance, NPP test0.20.31.00.4-0.10.10.4-1.00.80.3-1.00.3-0.40.20.2
Locomotion velocity, NPP test0.20.31.50.2-0.3-0.10.2-0.81.10.1-1.20.6-0.6-0.00.0
Pavlov. Cond. lever latency0.30.41.2-0.7-0.5-0.7-0.71.1-0.0-0.70.20.4-0.3-0.7-0.7
Pavlov. Cond. magazine entry latency1.31.72.21.41.41.51.4-1.40.41.50.8-1.41.31.41.5
Pavlov. Cond. change in total contacts1.92.14.6-1.4-1.4-1.3-1.41.0-2.1-1.3-1.61.3-1.4-1.4-1.3
Pavlov. Cond. index score1.31.62.71.41.31.51.4-1.60.51.50.4-1.21.01.41.5
Pavlov. Cond. latency score1.11.42.51.31.21.31.3-1.60.51.40.3-1.10.91.31.4
Pavlov. Cond. lever contacts0.30.41.20.60.50.70.6-1.10.10.7-0.1-0.40.30.70.8
Pavlov. Cond. magazine entry number1.21.52.1-1.2-1.3-1.5-1.31.2-0.1-1.4-0.81.4-1.3-1.3-1.4
Pavlov. Cond. intertrial magazine entries0.40.52.3-0.2-0.7-0.5-0.2-0.40.8-0.3-1.51.0-1.0-0.4-0.4
Pavlov. Cond. lever-magazine prob. diff.1.51.93.11.51.41.61.5-1.80.71.60.5-1.31.11.51.6
Pavlov. Cond. response bias0.30.40.90.60.60.80.6-0.9-0.40.7-0.1-0.60.40.70.8
Bone: apparent density0.10.21.90.20.10.20.1-0.3-1.40.3-0.1-0.10.10.10.2
Bone surface0.50.96.2-0.6-0.6-0.5-0.70.7-2.5-0.7-0.50.5-0.5-0.7-0.7
Bone volume0.50.95.9-0.6-0.6-0.6-0.70.6-2.4-0.7-0.50.6-0.6-0.7-0.7
Bone: connectivity density0.10.20.30.40.50.50.4-0.4-0.50.50.5-0.50.40.40.5
Bone: cortical apparent density0.60.81.3-1.0-0.9-1.1-0.90.9-0.3-0.9-0.80.9-0.9-0.9-1.0
Bone: cortical area2.74.15.2-1.9-2.1-2.2-1.91.6-1.9-2.0-2.32.2-2.1-2.2-2.1
Bone: cortical porosity0.00.00.4-0.1-0.2-0.1-0.1-0.00.6-0.1-0.00.2-0.2-0.2-0.1
Bone: cortical porosity0.20.20.70.40.40.40.4-0.50.90.40.5-0.30.30.30.4
Bone: cortical thickness1.83.03.9-1.6-1.8-1.9-1.61.2-1.6-1.7-2.01.9-1.9-1.9-1.7
Bone: cortical thickness0.40.51.20.80.60.60.8-1.10.60.8-0.1-0.40.40.60.7
Bone: cortical tissue density0.60.81.3-1.0-1.0-1.2-1.01.0-0.2-1.0-0.70.9-0.9-0.9-1.0
Bone: elastic displacement0.91.03.30.90.90.90.9-0.81.80.90.9-0.90.90.90.9
Bone: elastic work0.10.21.6-0.2-0.2-0.2-0.1-0.31.3-0.0-0.30.3-0.4-0.2-0.1
Bone: endosteal estimation0.00.10.1-0.3-0.2-0.3-0.30.3-0.0-0.2-0.30.2-0.2-0.1-0.3
Bone: endosteal perimeter0.51.02.7-0.8-1.1-1.1-0.90.5-0.3-0.9-1.61.2-1.2-0.9-1.0
Bone: final force0.40.71.0-0.9-0.9-1.0-0.90.9-0.3-0.9-0.50.7-0.8-0.8-0.9
Bone: final moment0.50.91.4-1.1-1.0-1.2-1.11.0-0.4-1.0-0.60.9-0.9-0.9-1.0
Bone: marrow area0.00.00.1-0.2-0.1-0.2-0.20.20.1-0.1-0.30.1-0.1-0.0-0.2
Bone: maximum diameter4.68.410.2-2.9-2.9-3.0-2.92.7-3.2-3.0-2.62.9-2.7-3.0-3.0
Bone: maximum force0.30.50.7-0.7-0.8-0.8-0.70.6-0.7-0.7-0.80.7-0.7-0.7-0.7
Bone: maximum moment0.50.81.0-0.9-0.9-1.0-0.90.7-0.8-0.8-0.90.9-0.9-0.9-0.9
Bone: minimum diameter0.00.10.30.20.00.00.2-0.4-0.30.2-0.50.1-0.10.10.1
Bone: periosteal estimation0.81.62.3-1.2-1.3-1.4-1.21.0-1.1-1.2-1.51.4-1.3-1.3-1.3
Bone: periosteal perimeter1.62.65.2-1.4-1.7-1.8-1.41.0-1.0-1.5-2.31.9-1.8-1.6-1.6
Bone: post-yield work0.20.31.8-0.4-0.4-0.3-0.40.4-1.3-0.5-0.70.5-0.4-0.5-0.5
Bone: stiffness0.00.10.60.20.10.10.20.0-0.80.2-0.1-0.20.20.20.1
Bone: tissue strength0.20.20.9-0.10.2-0.1-0.10.8-0.5-0.10.9-0.40.50.1-0.1
Bone: trabecular number0.10.21.70.10.20.10.0-0.2-1.30.20.0-0.20.10.10.2
Bone: trabecular spacing0.70.91.2-1.0-1.0-1.1-1.00.9-0.1-1.1-0.81.1-1.0-1.1-1.1
Bone: trabecular thickness0.70.92.01.10.90.91.0-1.40.21.20.2-0.70.61.01.1
Bone: trabecular tissue density0.50.71.90.60.70.80.7-0.11.30.51.4-0.80.90.70.6
Breakpoint value in progressive ratio session1.01.21.5-1.1-1.1-1.2-1.10.9-0.0-1.2-1.01.2-1.1-1.2-1.2
Distance traveled before self-admin0.20.20.4-0.5-0.3-0.5-0.40.6-0.6-0.4-0.00.2-0.2-0.4-0.4
Distance traveled after self-admin0.20.30.6-0.5-0.6-0.5-0.50.20.2-0.4-0.80.6-0.7-0.5-0.5
Delta time in closed arm before/after self-admin6.86.68.62.82.72.92.8-2.81.92.71.7-2.42.42.72.8
Delta time in open arm before/after self-admin7.26.89.7-2.8-2.7-3.1-2.82.9-1.0-2.8-1.92.6-2.5-2.8-2.9
Diff in mean of infusions in LGA sessions0.30.30.70.40.50.50.4-0.80.90.6-0.0-0.30.30.50.6
Extinction: sum of active levers before priming0.60.61.3-0.8-0.8-0.8-0.80.61.1-0.8-0.60.8-0.8-0.7-0.7
Active lever presses in extinction session 60.10.10.2-0.2-0.2-0.2-0.1-0.20.4-0.1-0.50.3-0.3-0.3-0.2
Delta distance traveled before/after self-admin0.30.31.30.50.30.50.5-0.91.10.4-0.2-0.10.00.40.5
Delta ambulatory time before/after self-admin0.40.51.70.70.50.70.6-1.01.30.60.1-0.30.30.60.7
Time in closed arm before self-admin0.30.40.7-0.7-0.6-0.8-0.70.8-0.3-0.7-0.20.5-0.5-0.7-0.7
Time in closed arm after self-admin2.12.23.11.51.41.61.5-1.41.81.51.2-1.41.31.51.5
Time in open arm before self-admin2.52.73.71.71.71.91.6-1.71.41.61.3-1.61.61.71.8
Time in open arm after self-admin0.10.10.2-0.4-0.4-0.4-0.40.40.4-0.4-0.30.3-0.3-0.3-0.4
Sum of active levers in priming session hrs 5-61.31.21.6-1.1-1.2-1.2-1.10.6-1.2-1.1-1.21.2-1.3-1.1-1.0
Time to tail flick, vehicle, before self-admin0.20.20.8-0.0-0.00.30.0-0.90.90.1-0.60.3-0.30.00.2
Time to tail flick, vehicle, after self-admin0.20.20.4-0.4-0.3-0.2-0.4-0.3-0.4-0.2-0.60.5-0.6-0.3-0.1
Time to tail flick, test, before self-admin0.90.92.10.81.10.80.8-0.1-0.40.81.4-1.31.30.90.8
Time to tail flick, test, after self-admin3.13.24.6-1.7-1.9-1.8-1.81.0-0.8-1.8-2.12.2-2.1-1.9-1.8
Delta time to tail flick, vehicle, before/after SA0.00.00.10.10.10.00.1-0.1-0.40.10.0-0.00.0-0.00.0
Delta time to tail flick, test, before/after SA2.82.53.9-1.5-1.8-1.6-1.50.8-0.8-1.5-2.01.9-2.0-1.6-1.5
Ambulatory time before self-admin0.60.62.2-0.7-0.7-0.8-0.70.7-1.5-0.7-0.60.6-0.6-0.7-0.7
Ambulatory time after self-admin0.30.30.6-0.4-0.6-0.5-0.50.00.4-0.5-0.80.7-0.7-0.5-0.5
Total heroin consumption0.20.32.2-0.5-0.2-0.3-0.50.21.5-0.30.20.2-0.2-0.4-0.2
Area under the delay curve3.13.35.0-1.8-2.0-1.8-1.81.1-0.1-1.8-2.22.2-2.1-1.9-1.8
Delay disc. indifference point, 0s delay0.60.70.9-0.8-0.8-0.9-0.80.6-0.8-0.8-0.90.9-0.8-1.0-0.9
Delay disc. indifference point, 16s delay2.42.43.0-1.7-1.7-1.6-1.71.30.3-1.7-1.51.7-1.7-1.7-1.6
Delay disc. indifference point, 2s delay1.21.43.1-1.0-1.2-1.1-1.00.2-0.5-1.0-1.71.5-1.5-1.2-1.0
Delay disc. indifference point, 24s delay1.61.62.0-1.4-1.3-1.3-1.40.90.4-1.3-1.11.4-1.4-1.3-1.3
Delay disc. indifference point, 4s delay3.03.25.8-1.7-1.9-1.8-1.70.9-0.6-1.7-2.42.2-2.2-1.8-1.7
Delay disc. indifference point, 8s delay1.01.02.2-0.9-1.1-0.9-0.90.40.1-1.0-1.51.3-1.3-1.1-1.0
Delay discount exponential model param2.83.04.51.71.91.71.7-1.0-0.01.72.1-2.12.01.81.7
Delay discount hyperbolic model param3.03.25.01.81.91.81.7-1.00.21.82.2-2.22.11.91.8
Fecal boli incidents, locomotor time 10.20.20.30.50.40.60.5-0.6-0.50.40.2-0.40.40.40.5
Change in fecal boli incidents, locomotor task0.20.20.7-0.4-0.2-0.4-0.40.80.7-0.30.5-0.00.0-0.1-0.3
Time >=10cm from walls, locomotor time 10.40.40.70.80.60.80.8-0.3-0.20.40.7-0.60.80.40.5
Bouts of movement, locomotor time 10.40.51.8-0.8-0.5-0.6-0.71.30.1-0.80.50.3-0.2-0.7-0.8
Total resting periods, locomotor time 10.20.20.9-0.5-0.3-0.3-0.51.00.1-0.50.60.1-0.0-0.4-0.4
Rest time, locomotor task time 10.10.10.50.10.10.30.10.30.1-0.20.7-0.10.3-0.1-0.0
Distance moved, locomotor task time 10.30.41.0-0.6-0.6-0.7-0.60.00.5-0.4-1.00.7-0.8-0.4-0.5
Vertical activity count, locomotor time 10.10.10.2-0.3-0.3-0.4-0.30.10.5-0.1-0.40.3-0.3-0.2-0.2
Time >=10cm from walls, locomotor time 20.90.91.51.20.91.11.2-1.11.20.90.1-0.60.80.80.9
Bouts of movement, locomotor time 20.50.62.7-0.5-0.7-0.5-0.5-0.60.5-0.1-1.60.9-1.2-0.2-0.3
Total resting periods, locomotor time 20.50.62.4-0.6-0.8-0.6-0.6-0.40.4-0.3-1.50.9-1.2-0.3-0.4
Rest time, locomotor task time 20.10.10.80.00.20.2-0.00.3-0.9-0.10.7-0.30.30.00.1
Distance moved, locomotor task time 20.20.30.80.60.40.50.6-0.50.90.50.2-0.30.40.50.4
Vertical activity count, locomotor time 20.40.40.70.80.70.80.8-0.60.60.60.5-0.50.70.50.6
Weight adjusted by age0.40.41.4-0.5-0.6-0.7-0.50.4-1.2-0.6-0.70.6-0.6-0.7-0.6
Seeking ratio, delayed vs. immediate footshock0.91.07.30.70.40.60.6-1.22.70.7-0.5-0.20.10.70.7
Locomotion in novel chamber4.96.17.82.72.72.82.7-2.30.52.62.1-2.62.62.52.6
Locomotion in novel chamber post-restriction3.13.74.62.02.02.12.0-1.91.32.01.6-1.81.92.12.0
Progressive ratio0.70.98.10.40.50.50.3-0.82.80.50.3-0.30.40.40.5
Food seeking constrained by brief footshock1.92.35.4-1.2-1.6-1.4-1.20.3-1.5-1.2-2.31.9-1.9-1.4-1.3
Seeking ratio, punishment vs. effort2.12.612.3-1.1-1.4-1.3-1.00.8-3.5-1.1-1.71.5-1.5-1.3-1.3
Run reversals in cocaine runway, females0.40.40.70.60.50.70.6-0.90.80.60.1-0.50.40.60.7
Run reversals in cocaine runway, males0.20.20.5-0.5-0.5-0.5-0.50.7-0.3-0.6-0.20.4-0.3-0.6-0.6
Latency to leave start box in cocaine runway0.30.41.8-0.5-0.5-0.6-0.5-0.0-1.3-0.1-0.80.5-0.7-0.2-0.3
Latency to leave start box in cocaine runway, F1.21.37.4-0.9-0.9-1.0-0.90.4-2.7-0.6-1.00.9-1.0-0.8-0.8
Latency to leave start box in cocaine runway, M0.60.62.10.60.60.60.7-0.71.40.80.3-0.70.50.90.7
Cd content in liver0.20.20.60.40.40.40.4-0.60.80.50.1-0.40.30.50.5
Co content in liver0.10.20.4-0.6-0.4-0.4-0.60.5-0.2-0.4-0.30.2-0.4-0.3-0.3
Cu content in liver0.40.50.9-0.8-0.7-0.8-0.80.9-0.5-0.8-0.10.6-0.6-0.7-0.8
Fe content in liver0.30.30.90.40.50.50.4-0.30.90.50.9-0.50.60.50.5
K content in liver0.70.73.0-0.3-0.8-0.7-0.3-0.2-0.6-0.5-1.71.1-1.1-0.7-0.6
Mg content in liver0.50.51.4-0.5-0.7-0.6-0.60.4-1.2-0.7-0.80.7-0.7-0.7-0.6
Mn content in liver0.30.42.2-0.2-0.5-0.3-0.2-0.40.1-0.3-1.50.7-0.8-0.3-0.3
Na content in liver3.53.74.6-2.0-2.0-2.0-2.02.0-1.4-2.1-1.41.9-1.8-2.1-2.1
Rb content in liver2.63.33.7-1.8-1.9-1.9-1.81.6-1.6-1.9-1.61.9-1.9-1.9-1.9
Se content in liver1.72.12.8-1.4-1.6-1.5-1.41.0-0.9-1.5-1.41.6-1.7-1.6-1.5
Sr content in liver1.71.52.1-1.4-1.3-1.5-1.41.2-0.0-1.3-0.81.3-1.3-1.3-1.4
Zn content in liver0.50.61.9-0.4-0.7-0.7-0.40.0-1.0-0.5-1.40.9-0.9-0.6-0.6