Hub : Genes

Extl3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression ENSRNOG00000013581 0.18 0.09 1.2e-13 0.14 0.16 0.16 0.15 4.3e-13 1.3e-14 2.5e-14 1.4e-13
2 Liver gene expression ENSRNOG00000013581 0.05 0.03 2.2e-07 0.06 0.05 0.05 0.05 6.2e-07 1.5e-06 1.2e-06 1.9e-06
3 NAcc alternative TSS ENSRNOT00000018583 0.08 0.05 2.2e-03 0.06 0.04 0.05 0.06 2.4e-05 8.9e-04 7.1e-05 4.3e-05
4 NAcc alternative TSS ENSRNOT00000077197 0.07 0.05 4.0e-03 0.06 0.03 0.04 0.05 5.6e-05 3.1e-03 3.4e-04 1.7e-04
5 NAcc gene expression ENSRNOG00000013581 0.06 0.03 3.8e-05 0.05 0.06 0.06 0.05 2.3e-04 2.4e-05 4.4e-05 7.8e-05
6 PL gene expression ENSRNOG00000013581 0.06 0.03 9.0e-04 0.05 0.05 0.05 0.05 7.5e-05 2.0e-04 2.0e-04 1.4e-04
7 PL mRNA stability ENSRNOG00000013581 0.08 0.05 1.4e-03 0.02 0.03 0.03 0.03 1.1e-02 1.5e-03 2.4e-03 2.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail0.51.54.91.6-2.2-0.00.01.40.61.0
BMI without tail0.81.64.2-0.60.5-2.12.1-0.9-0.71.0
Body weight1.14.89.02.8-3.01.6-1.62.52.2-0.6
Epididymis fat weight0.10.20.4-0.3-0.2-0.00.0-0.5-0.70.6
Glucose0.30.51.5-0.4-0.4-0.70.7-0.2-0.81.2
Heart weight0.30.41.1-0.0-0.11.0-1.00.30.3-0.8
Left kidney weight1.74.76.01.8-1.92.3-2.32.52.4-2.0
Right kidney weight2.57.110.52.7-2.12.6-2.62.83.2-2.5
Tail length0.20.51.6-0.51.3-0.40.4-0.80.2-0.9
Length with tail0.83.14.11.6-1.02.0-2.01.51.9-1.9
Length without tail3.88.310.82.9-3.03.3-3.33.12.6-1.6
Liver weight, left2.23.65.11.5-2.22.2-2.22.31.6-0.8
Liver weight, right0.81.32.91.4-1.70.6-0.61.50.90.3
Parametrial fat weight3.46.69.6-2.42.4-2.52.5-3.1-3.01.9
Retroperitoneal fat weight0.72.45.3-1.60.7-1.01.0-1.9-2.31.5
Intraocular pressure1.01.43.5-1.41.9-0.60.6-1.4-0.9-0.7
Extensor digitorum longus weight4.015.930.84.8-5.53.1-3.15.23.4-0.2
Soleus weight0.20.41.10.7-1.1-0.40.40.5-0.21.0
Tibialis anterior weight4.615.727.55.0-5.22.9-2.95.13.8-0.5
Tibia length2.15.89.62.5-1.32.4-2.42.23.1-2.7
Number of licking bursts0.50.61.20.5-0.8-1.11.10.2-0.10.9
Food consumed during 24 hour testing period0.30.30.50.40.10.7-0.70.50.6-0.7
Times rat made contact with spout0.30.30.8-0.30.4-0.90.9-0.4-0.40.5
Mean time between licks in bursts1.52.16.2-1.72.5-0.70.7-1.7-0.4-1.2
Mean num. licks in bursts0.30.41.1-0.71.10.4-0.4-0.5-0.3-0.5
Std. dev. time between licks in bursts0.50.61.9-0.51.40.1-0.1-0.9-0.1-1.0
Water consumed over 24 hours0.80.91.61.3-1.10.6-0.61.21.1-0.4
Indifference point 0 sec0.50.71.31.1-0.21.0-1.00.40.9-1.0
Indifference point AUC0.91.13.0-0.70.2-1.11.1-0.5-1.11.7
Indifference point function ln k1.11.51.81.3-0.81.3-1.31.11.3-1.3
Indifference point function log k1.11.51.81.3-0.81.3-1.31.11.3-1.3
Delay discounting total patch changes 0 sec0.61.02.11.4-0.51.1-1.10.71.0-0.9
Delay discounting total patch changes 12 sec0.20.20.60.8-0.4-0.50.50.10.10.7
Delay discounting total patch changes 18 sec0.50.60.9-0.50.6-0.80.8-0.8-0.90.9
Delay discounting total patch changes 24 sec0.10.10.60.8-0.30.1-0.10.30.5-0.1
Delay discounting total patch changes 6 sec0.10.10.20.3-0.2-0.40.40.00.10.2
Delay discounting time to switch 0 sec0.20.20.5-0.20.2-0.70.7-0.6-0.50.2
Delay discounting water rate 0 sec0.60.92.01.4-0.90.6-0.61.21.1-0.1
Delay discounting water rate 12 sec0.40.61.30.6-0.21.1-1.10.80.7-0.6
Delay discounting water rate 18 sec2.53.36.12.1-2.51.3-1.32.41.7-0.5
Delay discounting water rate 24 sec0.10.10.3-0.50.00.1-0.1-0.0-0.50.3
Delay discounting water rate 6 sec1.11.62.51.3-0.81.6-1.61.51.2-0.8
Locomotor activity3.96.37.82.8-2.22.7-2.72.62.5-1.9
Locomotor testing distance1.11.83.01.3-0.41.6-1.60.91.4-1.7
Locomotor testing rearing1.72.77.91.00.51.7-1.70.61.8-2.8
Light reinforcement 10.40.82.5-0.10.2-1.61.6-0.6-0.10.6
Light reinforcement 20.81.12.2-1.00.6-1.51.5-0.9-0.70.7
Reaction time number correct0.20.30.7-0.80.7-0.40.4-0.6-0.3-0.4
Reaction time mean minus median1.11.42.01.1-0.81.4-1.41.21.1-1.1
Reaction time mean minus median AUC0.60.81.40.8-0.40.8-0.80.91.0-1.2
Reaction time num false alarms0.81.12.61.6-1.10.1-0.11.01.5-0.6
Reaction time num false alarms AUC0.70.92.31.5-1.20.1-0.11.01.3-0.5
Reaction time trials correct on left0.20.30.7-0.80.7-0.40.4-0.6-0.3-0.4
Reaction time trials on left0.30.40.9-0.90.8-0.40.4-0.7-0.3-0.5
Reaction time mean0.81.12.4-0.10.41.4-1.40.60.8-1.6
Reaction time mean AUC1.31.73.60.30.11.7-1.71.01.3-1.9
Median of all reaction times0.70.92.3-0.50.81.2-1.20.30.6-1.5
Reaction time omissions0.81.13.1-1.31.7-0.30.3-1.1-0.2-1.2
Reaction time false alarm rate0.71.02.81.7-1.40.1-0.11.11.2-0.0
Reaction time premature initiation rate0.30.40.80.3-0.70.9-0.90.60.00.3
Reaction time premature initiations0.10.10.3-0.3-0.20.5-0.50.1-0.20.1
Std. dev. reaction times0.40.51.10.20.11.0-1.00.50.5-0.9
Reaction time trials completed0.30.40.9-0.90.8-0.40.4-0.7-0.3-0.5
Reaction time trials AUC0.30.41.1-1.00.9-0.40.4-0.7-0.4-0.5
Social response proportion1.92.15.8-2.41.9-0.10.1-1.6-1.6-0.1
Social responses2.02.54.8-2.22.2-0.60.6-2.1-1.7-0.0
Social time1.01.23.70.40.51.1-1.10.51.4-1.9
Conditioned locomotion0.50.61.0-1.00.7-0.70.7-0.9-0.90.5
Cocaine response after cond. corrected0.91.12.3-0.80.0-1.01.0-0.7-1.31.5
Cocaine response after cond. not corrected0.80.92.1-0.4-0.2-1.11.1-0.6-1.11.4
Cocaine response before conditioning0.40.51.31.1-0.40.4-0.40.61.1-0.7
Saline control response0.00.10.20.40.00.2-0.20.20.3-0.3
Condit. Reinf. active minus inactive responses0.30.30.7-0.50.5-0.50.5-0.7-0.80.6
Condit. Reinf. active-inactive response ratio0.10.10.3-0.50.2-0.10.1-0.3-0.50.4
Condit. Reinf. active responses0.40.50.7-0.50.7-0.70.7-0.8-0.90.6
Condit. Reinf. inactive responses0.81.01.7-0.81.3-1.01.0-1.3-1.00.4
Condit. Reinf. lever presses0.40.61.30.60.10.8-0.80.61.0-1.1
Condit. Reinf. lever reinforcers received0.10.20.3-0.20.4-0.40.4-0.4-0.50.4
Pavlov. Cond. lever latency2.63.55.1-1.50.9-2.32.3-1.9-2.11.8
Pavlov. Cond. magazine entry latency1.41.63.21.8-1.60.8-0.81.51.3-0.3
Pavlov. Cond. change in total contacts4.25.87.72.3-2.02.6-2.62.82.6-1.8
Pavlov. Cond. index score2.93.84.92.1-1.72.0-2.02.22.2-1.4
Pavlov. Cond. latency score3.03.95.12.1-1.62.0-2.02.22.2-1.6
Pavlov. Cond. lever contacts2.13.04.01.5-0.82.0-2.01.72.0-1.7
Pavlov. Cond. magazine entry number0.40.51.6-1.31.1-0.20.2-0.8-0.6-0.2
Pavlov. Cond. intertrial magazine entries5.57.113.2-3.13.6-2.32.3-3.4-2.20.2
Pavlov. Cond. lever-magazine prob. diff.2.73.54.72.1-1.71.8-1.82.22.1-1.2
Pavlov. Cond. response bias2.02.83.82.0-1.41.7-1.71.91.8-1.1
Conditioned reinforcement - actives5.85.79.0-2.93.0-2.02.0-2.8-2.40.7
Conditioned reinforcement - inactives1.11.23.2-1.11.8-1.01.0-1.2-0.4-0.4
Conditioned locomotion2.73.25.0-1.71.5-1.61.6-2.0-2.21.7
Intermittent access intake day 1-15 change0.40.40.9-1.00.70.4-0.4-0.8-0.8-0.4
Intermittent access intake escalation0.50.51.1-1.10.70.2-0.2-0.8-1.0-0.1
Intermittent access intake escalation 20.50.50.9-0.70.60.9-0.9-0.4-0.4-0.5
Intermitt. access day 1 inactive lever presses0.50.51.2-1.11.00.3-0.3-0.8-0.2-0.8
Intermitt. access day 15 inactive lever presses1.11.33.90.20.21.0-1.00.81.5-2.0
Intermitt. access escalation Index1.91.73.4-0.90.3-1.91.9-1.2-1.31.2
Intermittent access day 1 total infusions1.11.21.7-0.90.6-1.21.2-1.0-1.31.3
Intermittent access day 15 total infusions1.92.14.4-1.91.3-0.80.8-1.7-2.10.9
Intermittent access terminal intake (last 3 days)1.41.63.4-1.81.1-0.50.5-1.4-1.90.8
Intermittent access total infusions2.62.95.2-2.01.4-1.31.3-1.9-2.31.6
Intermittent access day 1 locomotion0.60.61.40.3-0.2-1.21.2-0.2-0.41.1
Intermittent access day 15 total locomotion0.40.41.0-0.90.6-0.30.3-0.7-1.00.5
Intermittent access total locomotion0.20.20.6-0.20.0-0.40.4-0.4-0.70.8
Intermittent access standard deviation1.21.32.6-1.31.11.6-1.6-0.6-0.8-0.4
Cocaine induced anxiety0.70.81.40.6-0.31.2-1.20.80.9-0.8
Post-drug Anxiety1.11.23.41.0-0.20.6-0.61.01.9-1.6
Baseline Anxiety0.40.51.50.40.1-1.21.2-0.30.10.2
Lifetime Intake2.62.95.3-2.11.6-1.21.2-1.9-2.31.3
Incentive Sensitization - Responses1.21.23.0-1.51.7-0.10.1-1.1-0.7-1.1
Incentive Sensitization - Breakpoint1.21.23.1-1.51.8-0.10.1-1.1-0.7-1.2
Progressive ratio test 1 active lever presses1.71.83.3-1.10.4-1.41.4-1.0-1.71.8
Progressive ratio test 1 breakpoint1.81.93.8-1.20.3-1.31.3-1.1-1.81.9
Progressive ratio test 1 inactive lever presses0.60.61.1-0.91.1-0.50.5-1.0-0.80.1
Progressive ratio test 2 active lever presses2.72.85.5-2.31.8-1.21.2-1.9-2.10.7
Progressive ratio test 2 breakpoint1.82.03.9-2.01.5-1.01.0-1.6-1.70.5
Progressive ratio test 2 inactive lever presses1.11.32.9-1.71.7-0.60.6-1.3-1.0-0.2
Total sessions with >9 infusions0.91.01.7-1.31.0-1.01.0-1.2-1.0-0.2
Short access day 1 total inactive lever presses0.60.72.0-1.40.7-0.00.0-0.8-1.20.6
Short access day 10 total inactive lever presses0.80.81.5-0.90.9-1.21.2-0.9-0.70.2
Short access day 1 total infusions2.62.76.6-2.61.8-0.70.7-1.9-2.00.3
Short access day 10 total infusions1.01.22.8-0.20.1-1.31.3-0.7-1.21.7
Short access total infusions0.80.91.8-1.20.7-0.60.6-1.1-1.40.6
Short access day 1 locomotion0.20.20.6-0.00.30.6-0.60.00.3-0.8
Short access day 10 total locomotion0.50.51.21.1-0.8-0.10.10.71.0-0.4
Short access total locomotion0.30.30.70.8-0.40.1-0.10.40.8-0.5
Compulsive drug intake1.31.33.50.5-0.4-1.91.9-0.3-0.21.1
One hour access (0.3 mA shock)2.12.44.1-1.30.7-1.61.6-1.6-2.01.7
One hour access (shock baseline)1.41.63.7-1.81.2-0.30.3-1.5-1.90.8
Number of responses in last shaping day0.50.51.30.4-0.51.1-1.10.3-0.1-0.4
Context. condit. distance diff. score3.64.35.3-2.21.2-2.32.3-2.1-2.32.1
Locomotion velocity, session 10.20.20.50.7-0.4-0.50.50.10.10.4
Locomotion distance, session 10.20.20.60.7-0.0-0.80.8-0.10.00.3
Locomotion velocity, session 20.20.20.50.7-0.5-0.30.30.0-0.30.7
Locomotion distance, session 20.20.30.70.60.3-0.80.8-0.30.1-0.1
Locomotion velocity, session 30.91.01.80.9-0.90.9-0.91.31.4-0.8
Locomotion distance, session 30.30.30.70.7-0.8-0.40.40.70.50.2
Stereotopy head waving bouts, day 31.01.22.5-0.00.41.6-1.60.40.9-1.6
Stereotopy head waving duration, day 32.12.54.21.1-0.82.1-2.11.51.6-1.5
Locomotion velocity, session 73.84.26.3-2.01.2-2.52.5-2.0-2.01.8
Locomotion distance, session 75.06.411.3-2.21.8-3.43.4-2.5-2.21.8
Stereotopy head waving bouts, day 71.71.92.61.6-1.41.3-1.31.61.5-0.7
Stereotopy head waving duration, day 73.84.76.31.9-1.82.5-2.52.42.3-1.5
Locomotion velocity, session 80.40.51.1-0.2-0.1-1.11.1-0.3-0.61.0
Locomotion distance, session 81.62.44.6-0.90.8-2.12.1-1.4-1.41.5
Degree of sensitization distance8.08.110.8-3.02.6-2.92.9-3.3-3.01.8
Degree of sensitization stereotypy1.11.22.01.3-1.40.9-0.91.31.0-0.2
Condit. Reinf. active minus inactive responses0.40.50.60.7-0.50.8-0.80.70.7-0.7
Condit. Reinf. active-inactive response ratio0.20.20.5-0.20.10.6-0.60.20.3-0.7
Condit. Reinf. active responses0.30.41.11.0-0.70.4-0.40.60.6-0.3
Condit. Reinf. inactive responses0.20.21.11.0-0.4-0.00.00.20.4-0.1
Incentive salience index mean1.41.62.71.6-1.51.2-1.21.41.2-0.5
Condit. Reinf. lever presses1.41.84.52.1-1.80.8-0.81.51.2-0.1
Time in familiar zone, hab. session 11.11.01.6-0.50.4-1.21.2-0.9-1.11.3
Time in novel zone, hab. session 11.21.21.91.0-1.31.2-1.21.41.0-0.4
Total zone transitions, hab. session 10.40.61.11.0-0.8-0.70.70.2-0.21.1
Total locomotion distance, hab. session 10.30.50.90.5-0.2-0.90.9-0.3-0.51.0
Locomotion velocity, hab. session 10.30.40.80.8-0.3-0.90.9-0.2-0.10.6
Time in familiar zone, hab. session 20.30.30.5-0.70.4-0.60.6-0.5-0.50.3
Time in novel zone, hab. session 20.00.00.20.4-0.2-0.10.10.1-0.00.2
Total zone transitions, hab. session 20.30.41.21.1-0.70.2-0.20.70.6-0.1
Total locomotion distance, hab. session 20.10.20.40.6-0.3-0.40.40.0-0.10.6
Locomotion velocity, hab. session 20.20.30.90.9-0.6-0.30.30.30.10.6
Novel to familiar place preference ratio0.40.51.0-0.50.5-0.50.5-0.8-1.00.7
Novelty place preference0.30.30.8-0.50.5-0.30.3-0.7-0.90.5
Time in novel zone, NPP test0.10.20.4-0.30.4-0.10.1-0.5-0.60.3
Total zone transitions, NPP test0.10.20.40.6-0.1-0.60.6-0.2-0.10.4
Total locomotion distance, NPP test1.01.42.6-0.51.3-1.61.6-1.5-0.80.3
Locomotion velocity, NPP test1.21.73.1-0.61.4-1.71.7-1.5-0.90.4
Pavlov. Cond. lever latency0.60.71.0-1.01.0-1.01.0-0.8-0.50.1
Pavlov. Cond. magazine entry latency0.91.22.00.8-0.81.4-1.41.11.0-0.9
Pavlov. Cond. change in total contacts2.02.13.31.8-1.81.5-1.51.61.0-0.0
Pavlov. Cond. index score2.02.63.61.9-1.91.5-1.51.81.6-0.6
Pavlov. Cond. latency score1.62.02.61.6-1.61.5-1.51.51.3-0.6
Pavlov. Cond. lever contacts1.51.82.81.3-1.31.7-1.71.41.2-0.7
Pavlov. Cond. magazine entry number1.51.92.6-1.41.5-1.41.4-1.6-1.40.8
Pavlov. Cond. intertrial magazine entries0.10.10.40.7-0.0-0.20.20.10.5-0.3
Pavlov. Cond. lever-magazine prob. diff.2.63.24.42.1-2.11.7-1.72.01.7-0.6
Pavlov. Cond. response bias2.12.63.61.6-1.81.7-1.71.91.6-0.8
Bone: apparent density0.30.51.1-0.31.0-1.01.0-0.70.1-0.4
Bone surface0.10.10.5-0.10.7-0.30.3-0.50.1-0.3
Bone volume0.30.41.20.20.4-1.11.1-0.5-0.20.4
Bone: connectivity density0.81.23.6-1.11.9-0.30.3-1.00.4-1.6
Bone: cortical apparent density0.10.20.4-0.1-0.4-0.60.60.1-0.10.6
Bone: cortical area0.81.23.21.1-1.3-0.90.90.3-0.51.8
Bone: cortical porosity2.12.33.31.8-1.71.5-1.51.71.3-0.5
Bone: cortical porosity1.51.72.41.5-1.51.4-1.41.41.0-0.4
Bone: cortical thickness1.01.74.01.5-2.0-0.80.80.8-0.21.9
Bone: cortical thickness3.23.711.50.3-1.2-2.12.1-0.5-2.03.4
Bone: cortical tissue density0.10.20.4-0.1-0.4-0.60.60.1-0.10.5
Bone: elastic displacement0.20.20.50.10.30.7-0.7-0.10.0-0.5
Bone: elastic work0.70.92.01.4-0.80.9-0.90.80.9-0.4
Bone: endosteal estimation0.00.10.2-0.20.4-0.10.1-0.3-0.2-0.1
Bone: endosteal perimeter0.20.31.1-0.51.1-0.20.2-0.7-0.4-0.4
Bone: final force0.40.71.91.2-1.4-0.10.10.70.01.1
Bone: final moment0.40.71.91.4-1.30.2-0.20.90.30.7
Bone: marrow area0.00.10.2-0.30.5-0.10.1-0.4-0.3-0.1
Bone: maximum diameter0.40.72.40.3-0.7-0.80.8-0.0-0.91.6
Bone: maximum force0.61.12.61.4-1.6-0.40.40.8-0.11.4
Bone: maximum moment0.61.02.61.6-1.6-0.10.11.00.20.9
Bone: minimum diameter0.20.30.90.8-0.8-0.10.10.3-0.30.9
Bone: periosteal estimation0.20.41.00.3-0.3-0.70.7-0.2-0.61.0
Bone: periosteal perimeter0.20.20.50.2-0.0-0.70.7-0.3-0.50.7
Bone: post-yield work4.76.413.2-0.9-0.1-3.23.2-1.5-2.83.6
Bone: stiffness0.30.51.61.0-1.3-0.20.20.80.30.7
Bone: tissue strength0.10.10.4-0.10.6-0.20.2-0.20.3-0.6
Bone: trabecular number0.50.71.7-0.71.3-0.90.9-1.0-0.1-0.5
Bone: trabecular spacing0.91.23.61.4-1.90.2-0.21.20.31.0
Bone: trabecular thickness0.30.40.91.0-0.6-0.80.80.40.30.5
Bone: trabecular tissue density1.21.73.61.8-1.90.8-0.81.71.20.1
Breakpoint value in progressive ratio session0.60.71.80.6-0.7-1.01.0-0.1-0.41.4
Distance traveled before self-admin0.10.10.2-0.00.4-0.10.10.00.3-0.3
Distance traveled after self-admin0.00.00.1-0.10.2-0.20.2-0.0-0.00.1
Delta time in closed arm before/after self-admin0.30.31.0-0.81.00.1-0.1-0.5-0.2-0.5
Delta time in open arm before/after self-admin0.00.00.1-0.3-0.0-0.10.1-0.2-0.30.1
Diff in mean of infusions in LGA sessions4.44.96.22.4-2.52.3-2.32.52.1-1.1
Extinction: sum of active levers before priming0.90.92.1-0.20.4-1.51.5-0.8-0.50.9
Active lever presses in extinction session 60.70.70.9-0.70.8-0.90.9-0.9-0.80.7
Delta distance traveled before/after self-admin0.10.10.20.2-0.50.5-0.50.30.00.2
Delta ambulatory time before/after self-admin0.10.10.20.1-0.30.4-0.40.1-0.40.5
Time in closed arm before self-admin2.12.44.32.1-1.80.9-0.91.91.8-0.7
Time in closed arm after self-admin0.60.61.31.1-0.60.4-0.40.91.0-0.6
Time in open arm before self-admin0.80.81.5-0.91.2-1.01.0-1.0-0.70.2
Time in open arm after self-admin0.30.30.7-0.80.7-0.50.5-0.7-0.3-0.3
Sum of active levers in priming session hrs 5-61.11.11.9-0.80.8-1.41.4-1.0-0.80.9
Time to tail flick, vehicle, before self-admin1.31.43.01.7-1.40.2-0.21.41.6-0.1
Time to tail flick, vehicle, after self-admin0.80.81.61.1-1.20.6-0.61.20.90.2
Time to tail flick, test, before self-admin0.40.40.91.0-0.3-0.60.60.50.9-0.4
Time to tail flick, test, after self-admin3.73.85.8-2.22.4-2.22.2-2.0-1.3-0.1
Delta time to tail flick, vehicle, before/after SA0.50.41.4-1.20.80.4-0.4-0.5-0.70.0
Delta time to tail flick, test, before/after SA3.73.36.6-2.62.3-1.41.4-2.0-1.60.2
Ambulatory time before self-admin0.10.10.2-0.00.3-0.40.4-0.10.00.3
Ambulatory time after self-admin0.20.20.30.6-0.50.4-0.40.50.20.3
Total heroin consumption0.30.40.60.7-0.70.6-0.60.80.50.0
Area under the delay curve2.42.57.42.3-2.7-0.30.31.20.21.8
Delay disc. indifference point, 0s delay0.20.20.30.5-0.3-0.30.3-0.4-0.50.5
Delay disc. indifference point, 16s delay1.71.73.71.7-1.9-0.70.70.90.11.9
Delay disc. indifference point, 2s delay0.40.41.31.2-1.10.0-0.00.3-0.10.6
Delay disc. indifference point, 24s delay2.32.35.81.5-2.1-1.21.20.6-0.52.4
Delay disc. indifference point, 4s delay1.71.84.71.9-2.20.6-0.61.50.70.8
Delay disc. indifference point, 8s delay2.72.89.32.3-3.00.3-0.31.70.71.3
Delay discount exponential model param2.52.78.2-2.32.90.1-0.1-1.4-0.3-1.8
Delay discount hyperbolic model param2.62.78.4-2.42.9-0.10.1-1.5-0.4-1.6
Fecal boli incidents, locomotor time 10.30.40.80.0-0.80.9-0.90.3-0.40.2
Change in fecal boli incidents, locomotor task0.20.20.8-0.10.30.4-0.40.20.6-0.9
Time >=10cm from walls, locomotor time 10.80.82.30.40.10.9-0.90.61.1-1.5
Bouts of movement, locomotor time 10.20.30.5-0.70.10.6-0.6-0.2-0.70.2
Total resting periods, locomotor time 10.50.61.6-1.00.30.1-0.1-0.6-1.30.9
Rest time, locomotor task time 10.40.41.6-0.3-0.1-0.60.6-0.3-0.61.3
Distance moved, locomotor task time 10.10.10.4-0.20.5-0.00.0-0.20.1-0.6
Vertical activity count, locomotor time 10.60.61.21.0-0.20.6-0.60.81.0-1.1
Time >=10cm from walls, locomotor time 20.80.82.00.00.51.1-1.10.41.0-1.4
Bouts of movement, locomotor time 20.60.72.30.7-1.50.3-0.30.7-0.31.0
Total resting periods, locomotor time 20.80.93.00.8-1.70.3-0.30.9-0.31.1
Rest time, locomotor task time 20.80.93.70.3-1.4-0.30.30.5-0.61.9
Distance moved, locomotor task time 20.30.31.2-0.01.1-0.20.2-0.50.4-0.8
Vertical activity count, locomotor time 20.20.20.50.70.4-0.30.30.00.7-0.5
Weight adjusted by age4.34.88.21.4-1.22.9-2.92.02.2-2.2
Seeking ratio, delayed vs. immediate footshock0.10.20.40.10.20.6-0.6-0.10.1-0.6
Locomotion in novel chamber0.60.81.41.2-1.0-0.90.90.90.90.1
Locomotion in novel chamber post-restriction0.30.40.70.1-0.5-0.90.90.1-0.40.9
Progressive ratio1.41.62.61.4-1.10.9-0.91.51.6-1.1
Food seeking constrained by brief footshock0.40.40.9-0.90.6-0.50.5-0.5-0.70.7
Seeking ratio, punishment vs. effort0.80.91.7-1.30.8-0.40.4-1.0-1.31.1
Run reversals in cocaine runway, females0.70.71.7-0.21.0-1.31.3-0.50.20.5
Run reversals in cocaine runway, males1.51.53.01.4-1.71.0-1.01.60.80.5
Latency to leave start box in cocaine runway0.70.82.2-1.51.10.4-0.4-0.7-0.8-0.6
Latency to leave start box in cocaine runway, F0.40.40.9-0.60.31.0-1.00.1-0.1-0.8
Latency to leave start box in cocaine runway, M0.70.71.6-1.11.3-0.00.0-0.8-0.1-1.0
Cd content in liver0.30.30.8-0.50.70.5-0.5-0.20.2-0.9
Co content in liver0.60.72.30.3-0.9-0.80.80.2-0.71.5
Cu content in liver0.30.40.60.4-0.60.8-0.80.70.6-0.4
Fe content in liver0.60.71.3-1.01.10.7-0.7-0.50.1-1.2
K content in liver0.90.91.6-0.50.5-1.21.2-0.9-0.90.9
Mg content in liver0.90.91.3-0.91.0-1.11.1-1.1-0.90.6
Mn content in liver1.82.13.0-1.01.2-1.71.7-1.7-1.41.1
Na content in liver6.97.310.63.3-2.62.7-2.72.92.9-1.5
Rb content in liver0.60.72.1-1.41.3-0.20.2-0.8-0.4-0.6
Se content in liver0.50.61.10.50.21.1-1.10.10.6-1.0
Sr content in liver0.70.72.2-1.01.50.1-0.1-0.90.0-0.9
Zn content in liver2.73.04.41.7-1.21.8-1.81.82.1-1.6