Hub : Genes

Ints9

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000013459 0.09 0.07 2.2e-08 0.08 0.06 0.06 0.06 5.4e-09 1.0e-07 2.1e-07 9.5e-08
2 LHb isoform ratio ENSRNOT00000096924 0.41 0.2 2.5e-03 -0.01 0.06 0.06 0.01 9.9e-01 1.5e-02 1.5e-02 2.3e-01
3 LHb isoform ratio ENSRNOT00000119472 0.23 0.15 5.2e-03 0.05 0.1 0.07 0.03 2.4e-02 2.6e-03 1.2e-02 7.1e-02
4 Liver alternative TSS ENSRNOT00000096924 0.02 0.02 4.0e-03 0.02 0.02 0.01 0.01 5.2e-03 6.3e-03 3.9e-02 2.8e-02
5 Liver alternative TSS ENSRNOT00000096924 0.02 0.02 4.0e-03 0.02 0.01 0 0.01 5.4e-03 7.5e-03 7.8e-02 3.3e-02
6 Liver gene expression ENSRNOG00000013459 0.15 0.07 1.2e-13 0.1 0.1 0.1 0.1 3.3e-11 6.3e-11 7.0e-11 5.4e-11
7 NAcc alternative TSS ENSRNOT00000096924 0.03 0.02 9.9e-03 0.02 0.02 0.01 0.01 2.1e-02 1.2e-02 4.5e-02 4.0e-02
8 OFC alternative polyA ENSRNOT00000119472 0.42 0.2 6.9e-04 0.03 0.07 0.08 0.07 6.5e-02 1.1e-02 5.4e-03 8.6e-03
9 OFC alternative polyA ENSRNOT00000018071 0.28 0.17 3.0e-03 0.04 0.04 0.08 0.04 4.9e-02 4.7e-02 6.6e-03 4.3e-02
10 OFC alternative polyA ENSRNOT00000119472 0.4 0.2 8.9e-04 0.04 0.06 0.05 0.06 3.9e-02 1.2e-02 2.5e-02 1.3e-02
11 PL intron excision ratio chr15:39234621:39237155 0.05 0.04 5.9e-03 0.03 0.01 0.01 0.02 2.1e-03 6.2e-02 8.8e-02 2.1e-02
12 PL intron excision ratio chr15:39237294:39239666 0.06 0.05 5.1e-03 0.03 0.01 0.01 0.01 3.0e-03 6.1e-02 2.7e-02 3.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail1.23.88.5-1.70.9-0.8-2.2-1.3-0.6-2.22.5-2.92.4-2.22.2
BMI without tail0.20.41.00.8-1.00.90.40.40.70.40.6-0.7-0.10.4-0.4
Body weight1.25.27.8-2.22.8-2.6-2.6-1.2-2.1-2.41.3-1.82.1-2.72.7
Epididymis fat weight0.10.31.20.30.7-0.10.11.10.60.20.7-0.60.20.1-0.1
Glucose0.50.82.3-0.4-1.21.0-0.3-0.30.9-0.61.4-1.50.9-0.30.3
Heart weight0.10.10.3-0.40.6-0.5-0.0-0.5-0.20.0-0.50.4-0.30.0-0.0
Left kidney weight1.02.95.6-2.21.9-2.3-1.7-2.1-2.4-1.5-0.5-0.10.7-1.61.6
Right kidney weight1.74.915.3-1.93.9-3.7-2.0-0.8-3.2-1.3-1.10.60.5-2.02.0
Tail length0.61.94.01.3-0.1-0.01.31.2-0.21.6-2.02.0-1.81.3-1.3
Length with tail0.41.65.3-0.82.3-2.2-0.70.1-1.9-0.3-1.21.0-0.3-0.70.7
Length without tail2.75.89.3-3.03.0-3.0-2.6-1.9-2.7-2.50.5-0.81.8-2.72.7
Liver weight, left1.93.16.1-2.50.8-1.3-2.0-2.3-1.6-2.10.8-1.31.6-1.91.9
Liver weight, right1.42.34.2-2.0-0.2-0.3-1.6-2.0-1.0-1.91.1-1.21.7-1.71.7
Parametrial fat weight2.44.68.92.4-2.22.62.42.43.02.2-0.10.8-1.42.3-2.3
Retroperitoneal fat weight0.51.75.51.1-1.31.71.21.52.31.00.9-0.6-0.31.3-1.3
Intraocular pressure1.92.74.51.9-0.60.71.71.10.82.0-1.71.9-2.12.0-2.0
Extensor digitorum longus weight5.522.039.9-5.81.4-2.4-5.6-6.3-3.4-5.92.9-3.35.0-5.65.6
Soleus weight0.41.22.3-1.2-0.20.1-1.0-1.20.1-1.21.4-1.51.4-1.11.1
Tibialis anterior weight5.619.228.9-5.32.2-3.0-5.3-5.4-3.8-5.32.2-2.84.5-5.35.3
Tibia length1.54.214.5-0.43.8-3.5-1.30.1-3.1-0.4-2.22.0-0.4-1.31.3
Number of licking bursts0.50.62.2-0.40.2-0.1-0.7-0.10.1-0.71.2-1.51.0-0.70.7
Food consumed during 24 hour testing period0.20.20.9-0.3-0.1-0.2-0.0-0.7-0.6-0.1-0.80.9-0.3-0.00.0
Times rat made contact with spout0.10.10.80.0-0.90.70.3-0.20.40.20.0-0.0-0.10.3-0.3
Mean time between licks in bursts3.54.98.32.3-0.20.42.52.30.52.8-2.62.6-2.92.5-2.5
Mean num. licks in bursts0.60.71.90.4-0.90.60.9-0.00.20.7-1.11.4-1.00.9-0.9
Std. dev. time between licks in bursts2.02.45.41.40.8-0.41.51.70.01.8-2.02.3-1.91.5-1.5
Water consumed over 24 hours0.80.92.5-1.30.3-0.7-1.1-1.6-1.1-1.1-0.0-0.00.8-1.11.1
Indifference point 0 sec0.60.93.00.31.7-1.3-0.10.7-0.90.3-1.31.7-0.5-0.20.2
Indifference point AUC1.41.76.6-0.2-2.62.0-0.1-1.41.1-0.61.6-1.60.9-0.10.1
Indifference point function ln k0.81.14.4-0.62.1-1.8-0.60.4-1.3-0.3-0.90.9-0.0-0.70.7
Indifference point function log k0.81.14.4-0.62.1-1.8-0.60.4-1.3-0.3-0.90.9-0.0-0.70.7
Delay discounting total patch changes 0 sec0.60.93.3-0.11.8-1.4-0.50.4-1.1-0.1-1.11.4-0.2-0.50.5
Delay discounting total patch changes 12 sec0.10.10.30.20.00.1-0.6-0.2-0.1-0.40.5-0.30.6-0.50.5
Delay discounting total patch changes 18 sec0.30.41.40.7-1.21.10.40.20.90.30.4-0.2-0.00.4-0.4
Delay discounting total patch changes 24 sec0.10.20.8-0.5-0.0-0.1-0.3-0.9-0.5-0.3-0.30.70.1-0.30.3
Delay discounting total patch changes 6 sec0.00.00.10.30.2-0.1-0.1-0.1-0.2-0.10.2-0.30.2-0.30.3
Delay discounting time to switch 0 sec0.20.31.70.80.6-0.20.31.30.50.7-0.10.2-0.40.4-0.4
Delay discounting water rate 0 sec0.71.11.9-1.00.5-0.7-1.2-1.2-1.2-1.30.3-0.41.0-1.41.4
Delay discounting water rate 12 sec0.30.40.6-0.50.7-0.7-0.7-0.6-0.8-0.6-0.40.60.3-0.70.7
Delay discounting water rate 18 sec2.83.67.1-2.70.9-1.3-2.2-2.2-1.8-2.50.9-1.12.0-2.22.2
Delay discounting water rate 24 sec0.10.20.5-0.3-0.50.5-0.1-0.70.4-0.40.7-0.70.4-0.20.2
Delay discounting water rate 6 sec0.71.12.5-1.40.2-0.7-1.1-1.6-1.2-1.2-0.30.50.7-1.21.2
Locomotor activity2.43.87.3-2.32.7-2.7-2.0-1.3-2.6-1.7-0.81.00.9-2.02.0
Locomotor testing distance1.11.87.0-0.32.0-1.7-0.10.7-1.50.2-2.12.7-0.8-0.10.1
Locomotor testing rearing2.94.516.80.72.4-2.10.71.5-1.81.3-3.64.1-2.10.8-0.8
Light reinforcement 10.10.21.60.80.00.20.31.30.10.50.1-0.1-0.10.2-0.2
Light reinforcement 20.40.61.90.7-1.41.10.80.70.70.60.3-0.5-0.30.7-0.7
Reaction time number correct0.40.61.00.7-0.60.40.90.40.20.9-0.90.8-1.00.9-0.9
Reaction time mean minus median0.70.92.8-1.11.7-1.6-0.9-0.3-1.1-0.6-0.30.30.3-1.01.0
Reaction time mean minus median AUC0.40.61.9-0.51.4-1.4-0.40.1-1.0-0.2-0.70.5-0.2-0.50.5
Reaction time num false alarms0.50.72.2-0.41.2-1.3-0.8-0.0-1.5-0.5-0.50.30.3-0.80.8
Reaction time num false alarms AUC0.40.51.7-0.60.8-1.0-0.8-0.4-1.3-0.6-0.30.20.4-0.80.8
Reaction time trials correct on left0.40.61.00.7-0.60.40.90.40.20.9-0.90.8-1.00.9-0.9
Reaction time trials on left0.50.71.30.8-0.70.51.00.50.21.0-1.00.9-1.11.0-1.0
Reaction time mean0.30.51.5-0.40.7-0.90.2-0.4-0.90.3-1.21.0-0.80.0-0.0
Reaction time mean AUC0.60.82.1-0.61.1-1.30.0-0.6-1.30.1-1.41.2-0.8-0.20.2
Median of all reaction times0.40.51.90.00.4-0.60.6-0.3-0.60.6-1.41.1-1.10.4-0.4
Reaction time omissions2.23.05.61.8-0.30.22.01.70.22.1-2.22.0-2.41.9-1.9
Reaction time false alarm rate0.70.91.4-0.81.1-1.1-1.2-0.5-1.1-1.00.4-0.51.0-1.21.2
Reaction time premature initiation rate0.50.61.2-0.90.5-0.3-0.8-0.7-0.1-0.91.0-1.11.0-0.70.7
Reaction time premature initiations0.10.10.3-0.4-0.10.1-0.2-0.40.1-0.30.5-0.60.4-0.10.1
Std. dev. reaction times0.10.20.5-0.50.6-0.7-0.1-0.2-0.5-0.1-0.50.4-0.3-0.20.2
Reaction time trials completed0.50.71.30.8-0.70.51.00.50.21.0-1.00.9-1.11.0-1.0
Reaction time trials AUC0.60.91.50.9-0.80.61.10.50.31.1-1.11.1-1.21.1-1.1
Social response proportion2.02.13.91.5-1.31.32.01.21.51.7-0.50.4-1.51.9-1.9
Social responses2.83.77.02.3-0.30.92.32.61.72.4-1.11.4-2.02.2-2.2
Social time1.21.55.20.41.0-1.20.50.3-1.50.8-2.32.2-1.40.5-0.5
Conditioned locomotion0.30.40.80.4-0.70.80.80.40.90.60.2-0.3-0.40.7-0.7
Cocaine response after cond. corrected0.91.03.8-0.2-1.11.20.10.11.3-0.21.7-2.00.80.0-0.0
Cocaine response after cond. not corrected0.60.72.7-0.0-0.80.9-0.10.41.0-0.31.5-1.70.8-0.20.2
Cocaine response before conditioning0.50.61.70.31.3-1.2-0.50.6-1.0-0.1-0.91.1-0.1-0.40.4
Saline control response0.10.10.40.10.5-0.4-0.1-0.0-0.30.0-0.50.6-0.1-0.00.0
Condit. Reinf. active minus inactive responses0.10.20.70.2-0.30.60.4-0.00.80.30.4-0.1-0.00.4-0.4
Condit. Reinf. active-inactive response ratio0.20.20.4-0.3-0.60.50.2-0.60.50.00.5-0.60.10.2-0.2
Condit. Reinf. active responses0.20.30.70.7-0.40.70.60.30.80.50.10.2-0.20.6-0.6
Condit. Reinf. inactive responses1.01.22.81.7-0.30.71.11.71.01.2-0.50.9-0.91.2-1.2
Condit. Reinf. lever presses0.40.52.10.20.7-0.8-0.0-0.4-1.00.1-1.31.4-0.5-0.10.1
Condit. Reinf. lever reinforcers received0.10.10.30.4-0.20.40.2-0.10.50.20.20.0-0.00.3-0.3
Pavlov. Cond. lever latency1.21.74.21.2-1.41.81.11.62.01.01.0-1.0-0.21.2-1.2
Pavlov. Cond. magazine entry latency1.61.83.5-1.21.9-1.6-1.7-0.9-1.2-1.30.5-0.51.2-1.61.6
Pavlov. Cond. change in total contacts2.83.86.8-2.21.9-2.3-2.1-2.6-2.6-2.0-0.30.11.1-2.12.1
Pavlov. Cond. index score2.12.75.0-1.52.2-2.2-1.9-1.7-2.1-1.5-0.30.30.9-1.81.8
Pavlov. Cond. latency score2.12.65.5-1.42.3-2.4-1.7-1.5-2.2-1.3-0.50.50.7-1.71.7
Pavlov. Cond. lever contacts1.11.53.7-1.01.2-1.6-1.0-1.4-1.9-0.8-1.31.40.0-1.01.0
Pavlov. Cond. magazine entry number0.60.81.40.7-1.10.91.20.50.50.9-0.60.4-1.01.1-1.1
Pavlov. Cond. intertrial magazine entries7.49.514.13.7-1.92.23.83.12.23.7-2.22.6-3.43.6-3.6
Pavlov. Cond. lever-magazine prob. diff.2.12.74.5-1.52.1-2.1-1.9-1.7-2.0-1.6-0.10.11.0-1.91.9
Pavlov. Cond. response bias1.41.93.1-1.51.5-1.7-1.6-1.6-1.7-1.4-0.40.50.8-1.61.6
Conditioned reinforcement - actives6.46.310.32.5-3.22.92.91.32.42.6-1.51.7-2.42.9-2.9
Conditioned reinforcement - inactives2.02.24.32.10.10.11.42.00.41.9-1.61.7-1.81.4-1.4
Conditioned locomotion1.72.05.11.6-1.82.01.31.22.31.10.8-0.7-0.41.4-1.4
Intermittent access intake day 1-15 change0.60.61.10.6-0.30.40.90.60.71.0-0.70.8-1.11.0-1.0
Intermittent access intake escalation0.60.61.20.5-0.70.80.90.31.00.9-0.40.5-0.91.1-1.1
Intermittent access intake escalation 20.30.30.70.2-0.00.10.60.20.30.7-0.60.6-0.80.8-0.8
Intermitt. access day 1 inactive lever presses1.11.22.91.41.1-0.61.01.70.21.5-0.90.6-1.41.0-1.0
Intermitt. access day 15 inactive lever presses0.91.03.10.01.2-1.50.1-0.2-1.50.4-1.81.3-1.10.0-0.0
Intermitt. access escalation Index0.80.72.00.6-1.21.30.70.51.40.50.6-0.5-0.10.8-0.8
Intermittent access day 1 total infusions0.80.94.30.4-2.11.80.6-0.41.30.10.7-0.50.20.5-0.5
Intermittent access day 15 total infusions1.61.84.40.9-2.02.01.40.32.11.10.20.0-0.81.5-1.5
Intermittent access terminal intake (last 3 days)1.61.86.50.5-2.62.21.2-0.51.90.70.3-0.2-0.61.3-1.3
Intermittent access total infusions1.92.16.31.1-2.52.41.30.32.30.90.7-0.5-0.41.3-1.3
Intermittent access day 1 locomotion0.20.20.7-0.2-0.30.4-0.30.20.4-0.30.8-0.70.7-0.30.3
Intermittent access day 15 total locomotion0.30.31.00.3-0.70.80.50.21.00.50.2-0.1-0.20.6-0.6
Intermittent access total locomotion0.10.20.5-0.1-0.20.40.00.30.7-0.00.7-0.60.30.1-0.1
Intermittent access standard deviation1.01.12.40.2-1.61.21.1-1.10.80.6-0.81.2-1.01.1-1.1
Cocaine induced anxiety0.40.51.2-0.61.1-1.0-0.5-0.7-0.9-0.3-0.71.00.0-0.50.5
Post-drug Anxiety1.41.65.2-0.32.3-2.1-0.50.5-1.90.2-1.51.5-0.6-0.50.5
Baseline Anxiety0.20.32.00.60.5-0.30.11.4-0.10.4-0.30.2-0.20.1-0.1
Lifetime Intake2.22.46.31.3-2.52.41.60.42.31.20.20.2-0.81.6-1.6
Incentive Sensitization - Responses2.42.44.41.4-1.30.91.80.50.81.7-1.71.5-2.12.0-2.0
Incentive Sensitization - Breakpoint2.62.64.91.4-1.20.91.90.60.71.8-1.91.7-2.22.0-2.0
Progressive ratio test 1 active lever presses1.51.55.40.1-2.32.10.4-0.61.7-0.21.5-1.40.60.3-0.3
Progressive ratio test 1 breakpoint1.61.65.30.0-2.32.10.3-0.51.8-0.21.7-1.60.70.3-0.3
Progressive ratio test 1 inactive lever presses0.90.91.31.1-0.60.61.10.90.81.2-0.80.9-1.01.1-1.1
Progressive ratio test 2 active lever presses2.72.97.61.2-2.82.41.80.22.11.4-0.20.1-1.22.0-2.0
Progressive ratio test 2 breakpoint2.02.25.81.0-2.42.01.60.21.71.3-0.40.3-1.21.8-1.8
Progressive ratio test 2 inactive lever presses1.51.82.51.5-1.31.11.60.71.11.6-1.11.0-1.51.6-1.6
Total sessions with >9 infusions1.31.52.31.1-1.00.91.51.01.01.4-1.01.0-1.41.5-1.5
Short access day 1 total inactive lever presses0.70.83.30.4-1.81.50.8-0.71.10.40.2-0.1-0.30.8-0.8
Short access day 10 total inactive lever presses0.60.61.71.2-0.10.30.91.30.71.0-0.1-0.1-0.70.9-0.9
Short access day 1 total infusions3.03.25.41.6-2.32.12.10.42.11.7-0.70.8-1.62.2-2.2
Short access day 10 total infusions0.80.83.0-0.1-1.71.6-0.0-0.51.2-0.41.1-0.60.8-0.10.1
Short access total infusions0.80.92.80.5-1.71.51.0-0.01.40.6-0.10.4-0.51.0-1.0
Short access day 1 locomotion0.40.41.80.00.1-0.20.40.0-0.30.5-1.21.3-0.80.5-0.5
Short access day 10 total locomotion0.50.62.3-0.51.5-1.3-0.60.7-1.0-0.3-0.0-0.10.3-0.60.6
Short access total locomotion0.30.31.2-0.21.1-1.0-0.30.6-0.80.0-0.60.6-0.1-0.20.2
Compulsive drug intake0.20.20.80.10.10.2-0.30.90.2-0.20.8-0.80.6-0.30.3
One hour access (0.3 mA shock)1.31.54.80.7-2.22.10.90.22.00.50.8-0.4-0.01.0-1.0
One hour access (shock baseline)1.51.85.10.8-2.32.11.4-0.31.90.90.10.3-0.71.4-1.4
Number of responses in last shaping day0.10.10.2-0.40.2-0.2-0.1-0.50.0-0.3-0.20.40.1-0.00.0
Context. condit. distance diff. score2.12.55.81.5-2.12.21.21.02.40.91.7-1.9-0.11.2-1.2
Locomotion velocity, session 10.10.10.2-0.10.2-0.1-0.40.1-0.1-0.30.30.00.4-0.40.4
Locomotion distance, session 10.10.10.90.0-0.30.30.0-0.20.00.0-0.40.9-0.00.1-0.1
Locomotion velocity, session 20.20.20.5-0.40.20.1-0.50.10.3-0.50.6-0.20.7-0.50.5
Locomotion distance, session 20.30.42.70.3-0.10.10.30.3-0.10.4-1.01.6-0.50.4-0.4
Locomotion velocity, session 30.70.81.6-1.10.6-1.0-1.1-1.0-1.3-1.00.1-0.60.6-1.01.0
Locomotion distance, session 30.50.61.0-0.90.3-0.4-0.9-0.4-0.5-0.80.7-1.00.9-0.90.9
Stereotopy head waving bouts, day 30.50.62.2-0.10.6-0.80.4-0.5-0.90.5-1.51.3-1.00.4-0.4
Stereotopy head waving duration, day 30.91.12.6-1.30.9-1.3-0.8-1.5-1.6-0.8-0.90.70.1-0.80.8
Locomotion velocity, session 71.92.14.71.6-1.31.61.21.62.21.21.4-1.7-0.31.2-1.2
Locomotion distance, session 72.43.05.82.4-1.72.01.82.12.31.80.6-0.6-0.91.7-1.7
Stereotopy head waving bouts, day 71.21.42.9-1.71.1-1.3-1.4-1.0-1.5-1.30.1-0.30.9-1.31.3
Stereotopy head waving duration, day 72.22.75.0-2.21.6-2.0-1.8-1.6-2.2-1.7-0.1-0.41.0-1.71.7
Locomotion velocity, session 80.30.41.1-0.0-0.90.8-0.2-0.30.6-0.41.0-1.00.6-0.20.2
Locomotion distance, session 80.60.92.31.1-1.41.50.70.71.50.60.8-0.6-0.10.7-0.7
Degree of sensitization distance5.55.69.83.1-2.22.62.72.43.02.60.10.2-1.62.6-2.6
Degree of sensitization stereotypy1.21.32.8-1.70.7-0.8-1.4-0.8-1.0-1.40.7-0.81.2-1.31.3
Condit. Reinf. active minus inactive responses0.30.40.8-0.60.9-0.8-0.5-0.8-0.7-0.4-0.30.40.1-0.60.6
Condit. Reinf. active-inactive response ratio0.10.10.4-0.20.0-0.20.2-0.7-0.30.1-0.50.4-0.40.1-0.1
Condit. Reinf. active responses0.40.41.5-0.51.2-0.9-0.7-0.5-0.6-0.4-0.10.40.4-0.70.7
Condit. Reinf. inactive responses0.30.42.10.31.4-0.9-0.40.8-0.4-0.0-0.30.60.1-0.40.4
Incentive salience index mean1.31.63.2-1.31.8-1.5-1.5-1.1-1.2-1.20.3-0.11.0-1.51.5
Condit. Reinf. lever presses1.62.24.6-1.32.1-1.7-1.8-0.8-1.2-1.50.7-0.31.5-1.91.9
Time in familiar zone, hab. session 10.50.51.40.4-1.01.20.40.61.20.20.7-0.40.20.4-0.4
Time in novel zone, hab. session 11.31.32.3-1.50.7-0.9-1.3-1.2-1.0-1.30.7-1.11.0-1.31.3
Total zone transitions, hab. session 10.40.51.2-0.6-0.40.4-0.8-0.70.1-0.90.9-0.41.1-0.80.8
Total locomotion distance, hab. session 10.10.10.30.1-0.20.4-0.20.40.5-0.20.50.10.5-0.20.2
Locomotion velocity, hab. session 10.10.10.50.40.3-0.0-0.20.40.1-0.1-0.10.70.3-0.20.2
Time in familiar zone, hab. session 20.20.20.50.4-0.70.60.40.20.50.30.1-0.2-0.20.4-0.4
Time in novel zone, hab. session 20.00.00.1-0.30.10.0-0.2-0.10.1-0.20.10.00.3-0.20.2
Total zone transitions, hab. session 20.30.30.9-0.70.1-0.3-0.7-0.9-0.6-0.7-0.00.30.5-0.70.7
Total locomotion distance, hab. session 20.10.10.3-0.1-0.10.2-0.4-0.20.2-0.40.4-0.10.6-0.40.4
Locomotion velocity, hab. session 20.20.30.7-0.4-0.00.0-0.7-0.5-0.0-0.70.5-0.10.8-0.70.7
Novel to familiar place preference ratio0.30.30.90.6-0.70.90.60.61.00.40.20.1-0.20.5-0.5
Novelty place preference0.30.30.70.6-0.50.70.60.70.80.5-0.00.3-0.30.5-0.5
Time in novel zone, NPP test0.20.20.40.5-0.30.50.40.50.60.4-0.10.3-0.20.4-0.4
Total zone transitions, NPP test0.00.00.30.20.10.1-0.00.00.10.0-0.10.60.1-0.00.0
Total locomotion distance, NPP test1.31.83.61.9-0.20.51.41.70.81.6-1.21.7-1.41.4-1.4
Locomotion velocity, NPP test1.31.83.51.9-0.40.71.41.70.91.6-1.11.6-1.31.4-1.4
Pavlov. Cond. lever latency0.60.71.80.7-1.41.01.00.40.50.8-0.60.5-0.91.0-1.0
Pavlov. Cond. magazine entry latency0.60.82.7-0.81.7-1.4-0.9-0.4-1.0-0.60.1-0.30.4-0.90.9
Pavlov. Cond. change in total contacts2.12.33.6-1.71.1-1.1-1.9-1.6-1.0-1.91.0-0.81.7-1.91.9
Pavlov. Cond. index score2.12.65.2-1.52.3-2.0-1.9-0.9-1.5-1.60.7-0.91.4-1.91.9
Pavlov. Cond. latency score1.51.94.3-1.32.1-1.8-1.6-0.7-1.3-1.30.6-0.71.1-1.61.6
Pavlov. Cond. lever contacts1.11.33.5-1.01.9-1.6-1.3-0.5-1.1-1.10.4-0.50.9-1.31.3
Pavlov. Cond. magazine entry number1.41.72.61.5-1.61.61.51.01.41.3-0.40.6-1.01.5-1.5
Pavlov. Cond. intertrial magazine entries0.20.20.90.30.4-0.4-0.00.1-0.50.1-0.70.9-0.2-0.10.1
Pavlov. Cond. lever-magazine prob. diff.2.63.25.3-1.72.3-2.1-2.1-1.1-1.7-1.80.9-1.11.6-2.12.1
Pavlov. Cond. response bias2.12.53.9-1.72.0-1.9-1.8-1.3-1.5-1.60.7-0.91.3-1.91.9
Bone: apparent density0.61.12.01.4-0.20.21.01.0-0.11.2-1.31.4-1.21.1-1.1
Bone surface0.40.62.00.9-0.10.10.70.5-0.10.8-1.11.4-0.90.8-0.8
Bone volume0.10.20.80.6-0.40.40.40.30.20.4-0.50.9-0.30.5-0.5
Bone: connectivity density2.43.76.52.20.6-0.51.92.2-0.42.3-2.52.3-2.51.9-1.9
Bone: cortical apparent density0.30.41.9-0.4-0.30.2-0.4-0.10.1-0.51.0-1.40.7-0.50.5
Bone: cortical area1.21.83.9-1.3-0.50.6-1.3-1.20.5-1.52.0-1.71.9-1.31.3
Bone: cortical porosity1.81.92.9-1.61.5-1.5-1.7-1.1-1.4-1.50.5-0.51.2-1.71.7
Bone: cortical porosity1.31.42.2-1.51.1-1.1-1.4-1.2-1.1-1.30.4-0.31.1-1.41.4
Bone: cortical thickness2.13.57.1-1.8-0.00.1-2.0-1.40.2-2.12.7-2.62.6-2.02.0
Bone: cortical thickness3.54.113.0-1.1-1.41.7-1.2-0.21.9-1.63.6-3.42.7-1.21.2
Bone: cortical tissue density0.30.41.8-0.4-0.40.2-0.4-0.20.1-0.51.0-1.30.7-0.40.4
Bone: elastic displacement0.30.31.6-0.00.4-0.20.30.6-0.00.4-0.81.3-0.50.3-0.3
Bone: elastic work0.40.61.1-1.10.9-0.8-0.8-0.4-0.8-0.6-0.51.00.4-0.80.8
Bone: endosteal estimation0.10.20.80.3-0.30.30.5-0.20.10.4-0.60.9-0.40.4-0.4
Bone: endosteal perimeter0.51.13.60.8-0.50.51.10.30.31.0-1.41.9-1.21.1-1.1
Bone: final force1.01.63.0-1.50.3-0.1-1.4-1.2-0.0-1.51.6-1.51.7-1.41.4
Bone: final moment0.81.32.3-1.50.4-0.4-1.3-1.3-0.4-1.41.0-0.91.5-1.41.4
Bone: marrow area0.10.30.90.3-0.40.40.5-0.10.30.4-0.60.9-0.50.5-0.5
Bone: maximum diameter0.61.12.4-0.9-1.11.0-0.7-1.20.8-1.11.5-1.21.4-0.70.7
Bone: maximum force1.22.14.2-1.7-0.20.2-1.6-1.50.1-1.81.7-1.42.1-1.61.6
Bone: maximum moment1.01.73.1-1.70.1-0.1-1.5-1.5-0.3-1.71.2-0.91.7-1.51.5
Bone: minimum diameter0.30.61.3-0.9-0.30.4-0.8-1.00.3-1.00.9-0.41.2-0.80.8
Bone: periosteal estimation0.10.30.5-0.5-0.70.7-0.3-0.70.5-0.50.7-0.30.7-0.30.3
Bone: periosteal perimeter0.00.10.20.1-0.30.50.0-0.10.4-0.10.20.20.30.0-0.0
Bone: post-yield work3.04.09.7-0.2-3.03.0-0.1-0.62.7-0.93.1-2.81.9-0.20.2
Bone: stiffness0.71.22.0-1.10.2-0.3-1.2-1.0-0.3-1.31.2-1.31.4-1.31.3
Bone: tissue strength0.60.62.10.1-0.50.20.7-0.1-0.30.6-1.31.4-0.90.7-0.7
Bone: trabecular number1.01.62.31.5-0.10.21.31.50.11.5-1.41.4-1.51.4-1.4
Bone: trabecular spacing2.02.64.7-1.90.3-0.3-1.9-1.4-0.3-2.01.8-1.82.2-1.81.8
Bone: trabecular thickness0.20.30.7-0.30.5-0.4-0.7-0.1-0.3-0.60.4-0.30.7-0.80.8
Bone: trabecular tissue density1.92.64.2-1.61.3-1.3-2.0-1.2-1.2-1.91.2-1.41.8-2.02.0
Breakpoint value in progressive ratio session0.70.72.4-0.40.6-0.1-0.70.90.5-0.61.6-1.41.2-0.60.6
Distance traveled before self-admin0.20.30.80.1-0.80.40.4-0.6-0.30.2-0.80.9-0.40.2-0.2
Distance traveled after self-admin0.20.31.6-0.1-1.30.80.1-0.50.0-0.1-0.40.6-0.10.2-0.2
Delta time in closed arm before/after self-admin0.50.51.11.10.2-0.00.70.80.20.9-0.80.8-0.90.6-0.6
Delta time in open arm before/after self-admin0.10.00.20.10.2-0.10.20.00.30.20.3-0.4-0.00.2-0.2
Diff in mean of infusions in LGA sessions3.94.410.5-2.63.2-2.8-2.3-0.8-2.1-2.00.7-0.91.7-2.22.2
Extinction: sum of active levers before priming0.30.31.50.90.10.30.11.20.70.50.3-0.10.00.3-0.3
Active lever presses in extinction session 60.40.41.40.9-0.60.70.61.20.80.60.2-0.2-0.30.4-0.4
Delta distance traveled before/after self-admin0.20.20.4-0.5-0.30.1-0.6-0.4-0.0-0.60.5-0.50.6-0.50.5
Delta ambulatory time before/after self-admin0.20.20.4-0.5-0.60.5-0.4-0.60.4-0.50.6-0.40.5-0.30.3
Time in closed arm before self-admin2.32.63.8-1.71.7-1.9-2.0-1.6-1.9-1.60.6-1.11.3-1.71.7
Time in closed arm after self-admin0.80.93.2-0.31.8-1.5-1.1-0.3-1.1-0.50.0-0.20.4-0.90.9
Time in open arm before self-admin1.11.22.41.0-1.61.31.20.40.80.9-1.01.4-1.01.1-1.1
Time in open arm after self-admin0.60.71.30.8-0.60.41.10.50.31.0-0.90.8-1.01.0-1.0
Sum of active levers in priming session hrs 5-60.60.61.61.0-1.01.00.81.30.90.70.1-0.1-0.30.6-0.6
Time to tail flick, vehicle, before self-admin1.91.93.8-0.81.9-1.7-1.7-0.1-1.6-1.30.6-0.81.3-1.71.7
Time to tail flick, vehicle, after self-admin1.81.92.8-1.60.6-0.7-1.6-1.4-0.9-1.51.2-1.51.5-1.71.7
Time to tail flick, test, before self-admin0.30.31.0-0.3-0.1-0.3-0.4-0.7-0.9-0.3-0.91.0-0.1-0.20.2
Time to tail flick, test, after self-admin3.94.06.62.6-1.11.22.22.01.32.4-1.61.7-2.22.4-2.4
Delta time to tail flick, vehicle, before/after SA0.50.52.2-0.1-1.51.10.6-0.70.80.3-0.10.1-0.50.7-0.7
Delta time to tail flick, test, before/after SA3.63.25.72.4-1.31.42.22.01.52.2-0.80.7-1.82.1-2.1
Ambulatory time before self-admin0.10.10.6-0.1-0.80.50.1-0.50.1-0.1-0.10.30.1-0.00.0
Ambulatory time after self-admin0.40.41.1-0.9-0.70.4-0.7-1.1-0.2-0.90.3-0.10.7-0.60.6
Total heroin consumption0.50.61.4-1.0-0.0-0.2-0.9-1.2-0.4-0.90.5-0.60.8-0.80.8
Area under the delay curve4.54.89.2-2.40.9-0.5-2.4-1.3-0.3-2.52.9-2.83.0-2.42.4
Delay disc. indifference point, 0s delay0.10.10.50.20.7-0.20.30.70.40.20.10.30.10.0-0.0
Delay disc. indifference point, 16s delay3.53.57.1-1.70.3-0.1-2.1-1.3-0.1-2.12.7-2.62.7-2.02.0
Delay disc. indifference point, 2s delay0.40.40.9-0.80.4-0.2-0.7-0.90.1-0.70.6-0.30.8-0.60.6
Delay disc. indifference point, 24s delay4.24.110.6-1.80.20.2-1.9-0.90.4-2.13.3-3.12.9-2.02.0
Delay disc. indifference point, 4s delay3.13.25.1-2.10.9-0.8-2.1-1.5-0.8-2.11.8-1.82.3-2.12.1
Delay disc. indifference point, 8s delay5.65.89.6-2.91.3-1.0-2.6-1.4-0.7-2.82.9-3.13.1-2.62.6
Delay discount exponential model param5.15.410.02.6-0.80.52.51.60.32.7-3.03.0-3.22.5-2.5
Delay discount hyperbolic model param5.05.39.52.7-0.90.72.61.80.52.7-2.82.7-3.12.5-2.5
Fecal boli incidents, locomotor time 10.70.73.1-1.1-1.40.9-0.1-1.80.4-0.80.7-0.60.6-0.00.0
Change in fecal boli incidents, locomotor task0.40.41.60.51.3-1.00.20.8-0.60.4-0.70.4-0.5-0.00.0
Time >=10cm from walls, locomotor time 10.91.02.90.31.3-1.30.10.3-1.20.4-1.71.7-0.90.1-0.1
Bouts of movement, locomotor time 10.30.30.7-0.3-0.80.70.3-0.70.8-0.20.7-0.80.20.3-0.3
Total resting periods, locomotor time 10.80.92.0-0.1-1.41.30.4-0.71.3-0.21.3-1.40.40.4-0.4
Rest time, locomotor task time 10.70.82.6-0.2-1.41.2-0.3-0.20.7-0.61.5-1.60.9-0.20.2
Distance moved, locomotor task time 10.50.51.70.60.6-0.40.40.6-0.20.8-1.11.3-0.90.5-0.5
Vertical activity count, locomotor time 10.80.83.8-0.20.7-0.9-0.3-0.8-1.1-0.1-1.51.9-0.4-0.30.3
Time >=10cm from walls, locomotor time 20.80.93.40.40.3-0.60.40.0-1.00.5-1.91.8-1.10.3-0.3
Bouts of movement, locomotor time 21.82.04.9-1.70.2-0.1-1.1-1.00.2-1.62.1-2.21.8-1.31.3
Total resting periods, locomotor time 22.62.87.2-2.0-0.00.0-1.4-1.30.2-1.92.4-2.72.1-1.51.5
Rest time, locomotor task time 23.54.110.6-1.8-2.01.4-1.4-2.00.6-2.13.0-3.32.4-1.31.3
Distance moved, locomotor task time 21.31.54.81.30.8-0.50.81.2-0.41.2-1.82.2-1.30.8-0.8
Vertical activity count, locomotor time 20.70.74.60.50.3-0.30.10.5-0.70.4-1.52.1-0.70.2-0.2
Weight adjusted by age1.71.94.8-1.31.9-2.1-1.1-1.2-2.2-0.8-1.21.0-0.0-1.11.1
Seeking ratio, delayed vs. immediate footshock0.50.52.40.61.6-1.00.11.3-0.20.5-0.50.6-0.40.2-0.2
Locomotion in novel chamber0.60.71.3-1.00.5-0.6-1.2-0.7-0.9-0.90.5-0.70.9-1.11.1
Locomotion in novel chamber post-restriction0.50.61.2-0.4-1.00.8-0.5-1.00.5-0.91.1-0.90.9-0.50.5
Progressive ratio0.80.92.5-1.30.7-1.2-0.8-1.1-1.6-1.0-0.60.50.4-0.90.9
Food seeking constrained by brief footshock0.30.41.70.5-0.60.60.30.60.70.10.9-1.30.20.1-0.1
Seeking ratio, punishment vs. effort0.50.61.70.8-0.71.00.40.71.30.51.1-1.20.10.4-0.4
Run reversals in cocaine runway, females0.20.21.01.0-0.30.30.00.5-0.20.5-0.50.7-0.30.1-0.1
Run reversals in cocaine runway, males3.13.06.8-2.2-0.2-0.2-1.8-2.6-0.8-2.21.5-1.52.1-1.91.9
Latency to leave start box in cocaine runway1.01.12.00.9-1.10.91.4-0.50.81.0-0.91.1-1.21.3-1.3
Latency to leave start box in cocaine runway, F0.20.31.20.3-0.40.20.6-1.10.10.2-0.50.5-0.50.5-0.5
Latency to leave start box in cocaine runway, M1.71.63.31.1-0.50.31.40.70.11.5-1.81.7-1.81.4-1.4
Cd content in liver0.40.51.20.30.1-0.20.70.3-0.20.8-1.11.1-1.00.7-0.7
Co content in liver1.31.63.1-1.2-1.10.9-0.9-1.60.7-1.31.7-1.61.6-0.90.9
Cu content in liver0.20.30.8-0.70.2-0.4-0.6-0.9-0.6-0.60.1-0.30.4-0.60.6
Fe content in liver0.91.12.01.20.6-0.41.11.4-0.11.3-1.10.9-1.41.0-1.0
K content in liver0.30.30.80.8-0.40.70.50.80.90.50.4-0.4-0.10.4-0.4
Mg content in liver0.60.61.00.8-0.91.01.00.60.90.9-0.20.2-0.70.9-0.9
Mn content in liver1.11.22.91.4-0.61.11.21.71.41.2-0.10.5-0.71.2-1.2
Na content in liver4.64.98.2-2.22.6-2.8-2.6-1.9-2.9-2.2-0.30.31.5-2.62.6
Rb content in liver0.81.01.81.3-0.50.41.30.80.41.2-0.90.7-1.31.3-1.3
Se content in liver0.81.03.60.61.9-1.30.11.3-0.60.6-1.11.4-0.70.1-0.1
Sr content in liver1.91.73.01.5-0.10.11.51.2-0.01.6-1.61.5-1.71.5-1.5
Zn content in liver1.61.84.4-1.41.7-1.9-1.2-1.1-2.1-0.9-1.01.00.2-1.21.2