Hub : Genes

Ighmbp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000013456 0.14 0.08 3.7e-06 0.02 0.02 0.01 0.02 4.8e-03 1.1e-03 8.6e-03 4.5e-03
2 BLA mRNA stability ENSRNOG00000013456 0.14 0.09 2.5e-05 0.09 0.09 0.08 0.08 2.2e-05 2.3e-05 5.2e-05 3.5e-05
3 Brain mRNA stability ENSRNOG00000013456 0.5 0.11 0.0e+00 0.46 0.46 0.49 0.46 7.9e-47 2.4e-47 5.2e-51 9.3e-48
4 IL mRNA stability ENSRNOG00000013456 0.28 0.17 8.2e-04 0.14 0.05 0.11 0.1 2.5e-04 2.1e-02 1.4e-03 1.8e-03
5 Liver gene expression ENSRNOG00000013456 0.07 0.04 4.8e-07 0.04 0.05 0.04 0.05 1.4e-05 2.1e-06 1.6e-05 4.2e-06
6 NAcc mRNA stability ENSRNOG00000013456 0.19 0.12 2.1e-08 0.1 0.09 0.09 0.09 4.1e-08 5.9e-07 3.6e-07 1.7e-07
7 OFC mRNA stability ENSRNOG00000013456 0.24 0.16 2.1e-03 0.05 0.07 0.05 0.06 2.9e-02 9.5e-03 2.3e-02 1.6e-02
8 PL mRNA stability ENSRNOG00000013456 0.21 0.1 8.1e-13 0.14 0.16 0.15 0.16 3.7e-11 4.7e-12 9.2e-12 5.5e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail1.13.56.5-1.3-0.2-1.5-2.32.5-2.5-0.9-2.3
BMI without tail0.71.62.8-0.90.1-1.0-1.71.7-1.5-0.7-1.6
Body weight2.410.416.1-3.4-1.4-3.3-4.00.5-3.9-3.2-4.0
Epididymis fat weight3.99.013.43.13.73.33.10.63.22.93.2
Glucose2.33.54.92.11.52.11.81.71.82.21.7
Heart weight1.42.02.71.51.21.61.50.51.61.51.5
Left kidney weight0.92.74.91.52.21.71.9-0.51.71.31.8
Right kidney weight0.71.92.81.01.71.41.5-1.21.70.81.5
Tail length1.23.55.1-2.2-1.6-1.9-2.0-1.6-1.5-2.3-1.8
Length with tail2.810.113.4-3.6-2.5-3.3-3.5-1.7-3.1-3.7-3.4
Length without tail2.35.16.6-2.5-1.6-2.4-2.5-0.8-2.5-2.5-2.6
Liver weight, left0.30.41.50.61.20.70.50.20.50.50.6
Liver weight, right0.30.51.50.41.20.70.7-0.50.90.20.6
Parametrial fat weight2.24.35.62.31.52.32.11.32.12.42.1
Retroperitoneal fat weight5.417.921.84.44.74.74.50.74.64.24.6
Intraocular pressure0.40.51.60.3-0.20.40.9-1.31.00.10.8
Extensor digitorum longus weight5.421.729.0-5.2-2.8-5.0-5.4-1.2-5.4-5.1-5.3
Soleus weight2.47.011.52.71.62.73.2-1.23.22.43.4
Tibialis anterior weight7.024.233.4-5.7-2.1-5.3-5.4-2.8-5.5-5.8-5.4
Tibia length0.20.51.9-0.70.5-0.5-0.3-1.4-0.4-1.0-0.4
Number of licking bursts0.00.00.20.10.0-0.00.00.5-0.20.20.0
Food consumed during 24 hour testing period0.30.40.60.60.70.60.7-0.20.70.50.8
Times rat made contact with spout0.30.40.9-0.3-0.8-0.5-0.50.9-0.7-0.2-0.7
Mean time between licks in bursts1.31.82.6-1.4-1.6-1.5-1.4-0.4-1.3-1.4-1.4
Mean num. licks in bursts0.00.00.2-0.1-0.4-0.1-0.10.3-0.0-0.0-0.2
Std. dev. time between licks in bursts1.21.42.5-1.3-1.5-1.1-0.8-1.6-0.6-1.4-0.9
Water consumed over 24 hours0.60.71.4-0.6-0.4-0.9-1.00.7-1.2-0.5-1.0
Indifference point 0 sec0.10.10.20.4-0.30.40.20.10.30.40.4
Indifference point AUC1.11.31.7-1.3-1.2-1.3-1.0-0.7-1.1-1.3-1.2
Indifference point function ln k2.94.15.92.21.62.12.3-0.02.32.02.4
Indifference point function log k2.94.15.92.21.62.12.3-0.02.32.02.4
Delay discounting total patch changes 0 sec0.10.10.8-0.2-0.9-0.2-0.1-0.5-0.0-0.2-0.0
Delay discounting total patch changes 12 sec2.22.93.9-1.9-1.8-1.7-2.0-0.3-1.6-1.8-2.0
Delay discounting total patch changes 18 sec0.30.40.8-0.6-0.6-0.7-0.80.2-0.9-0.5-0.8
Delay discounting total patch changes 24 sec1.41.82.3-1.4-1.5-1.4-1.4-0.7-1.2-1.4-1.4
Delay discounting total patch changes 6 sec0.60.91.5-0.8-0.7-0.9-1.20.8-1.1-0.7-1.2
Delay discounting time to switch 0 sec0.71.13.8-0.50.4-0.5-1.41.9-1.2-0.2-1.2
Delay discounting water rate 0 sec1.93.05.11.30.11.32.2-2.22.20.92.2
Delay discounting water rate 12 sec4.06.09.72.21.72.33.1-2.03.01.83.1
Delay discounting water rate 18 sec1.31.72.71.30.81.31.6-0.51.51.11.6
Delay discounting water rate 24 sec1.21.73.70.80.61.01.5-1.91.60.51.6
Delay discounting water rate 6 sec0.71.03.30.50.40.61.1-1.81.10.21.2
Locomotor activity0.91.52.41.11.51.31.4-0.41.50.91.3
Locomotor testing distance0.91.52.21.11.31.21.4-0.61.50.91.4
Locomotor testing rearing1.52.32.81.61.71.61.60.91.51.61.5
Light reinforcement 10.50.81.50.90.20.91.2-0.41.20.81.1
Light reinforcement 22.12.84.21.71.21.72.0-0.42.01.62.0
Reaction time number correct0.20.30.6-0.7-0.0-0.4-0.4-0.7-0.3-0.8-0.6
Reaction time mean minus median0.60.71.5-0.9-0.1-0.7-1.00.7-1.0-0.8-1.2
Reaction time mean minus median AUC0.50.61.3-1.0-0.3-0.6-0.80.1-0.6-0.9-1.1
Reaction time num false alarms0.30.41.3-0.6-0.5-0.7-0.2-1.1-0.5-0.7-0.3
Reaction time num false alarms AUC0.91.31.7-1.3-1.2-1.3-0.9-1.0-1.1-1.3-1.0
Reaction time trials correct on left0.20.30.6-0.7-0.0-0.4-0.4-0.7-0.3-0.8-0.6
Reaction time trials on left0.30.40.9-0.8-0.1-0.5-0.5-0.8-0.4-0.9-0.7
Reaction time mean0.20.31.10.41.10.40.10.80.00.40.1
Reaction time mean AUC0.30.41.60.61.20.50.30.90.10.60.3
Median of all reaction times0.30.41.20.71.10.50.30.90.20.70.4
Reaction time omissions1.01.42.3-1.4-0.7-1.2-1.3-0.1-1.2-1.3-1.5
Reaction time false alarm rate0.40.50.8-0.7-0.9-0.9-0.5-0.8-0.8-0.8-0.5
Reaction time premature initiation rate2.43.24.5-2.0-0.9-2.0-2.1-0.4-2.1-1.9-2.1
Reaction time premature initiations3.34.66.4-2.5-1.1-2.3-2.4-1.0-2.3-2.5-2.5
Std. dev. reaction times0.10.20.3-0.30.1-0.3-0.40.5-0.5-0.3-0.6
Reaction time trials completed0.30.40.9-0.8-0.1-0.5-0.5-0.8-0.4-0.9-0.7
Reaction time trials AUC0.20.30.6-0.7-0.1-0.5-0.5-0.6-0.3-0.8-0.6
Social response proportion0.50.51.4-0.6-1.2-0.6-0.60.6-0.6-0.4-0.8
Social responses0.30.40.6-0.7-0.8-0.6-0.4-0.4-0.5-0.7-0.6
Social time0.30.40.7-0.7-0.8-0.6-0.70.0-0.5-0.7-0.8
Conditioned locomotion2.52.94.3-2.0-1.5-1.8-1.5-1.9-1.3-2.1-1.5
Cocaine response after cond. corrected0.10.10.20.4-0.20.40.30.30.40.40.4
Cocaine response after cond. not corrected0.30.30.80.6-0.00.50.40.90.50.70.4
Cocaine response before conditioning0.10.10.70.20.20.10.10.8-0.10.3-0.0
Saline control response2.53.34.6-1.8-1.5-2.0-2.10.1-2.1-1.8-2.1
Condit. Reinf. active minus inactive responses1.51.82.61.50.71.51.31.61.31.61.1
Condit. Reinf. active-inactive response ratio3.43.64.52.01.82.12.01.12.02.01.8
Condit. Reinf. active responses0.50.73.00.8-0.30.60.51.70.41.00.3
Condit. Reinf. inactive responses0.91.12.0-0.7-1.4-1.0-1.11.0-1.2-0.5-1.1
Condit. Reinf. lever presses0.30.41.8-0.2-0.5-0.3-0.61.3-0.6-0.0-0.7
Condit. Reinf. lever reinforcers received0.40.63.00.6-0.60.40.21.70.10.8-0.0
Pavlov. Cond. lever latency0.10.10.3-0.3-0.5-0.4-0.3-0.5-0.3-0.3-0.2
Pavlov. Cond. magazine entry latency1.61.93.0-1.2-1.3-1.2-1.61.3-1.5-0.9-1.7
Pavlov. Cond. change in total contacts0.20.21.50.1-0.10.0-0.31.2-0.20.2-0.3
Pavlov. Cond. index score0.30.31.1-0.3-0.2-0.3-0.71.0-0.5-0.2-0.7
Pavlov. Cond. latency score0.20.20.9-0.20.1-0.2-0.51.0-0.4-0.1-0.6
Pavlov. Cond. lever contacts0.00.00.20.2-0.00.20.30.00.40.10.2
Pavlov. Cond. magazine entry number1.82.24.01.30.81.31.9-1.51.71.12.0
Pavlov. Cond. intertrial magazine entries0.50.61.20.80.10.70.9-0.60.80.71.1
Pavlov. Cond. lever-magazine prob. diff.0.40.51.1-0.6-0.4-0.6-0.91.0-0.8-0.4-1.0
Pavlov. Cond. response bias0.20.20.5-0.3-0.5-0.3-0.40.7-0.3-0.2-0.6
Conditioned reinforcement - actives0.30.30.70.20.80.20.6-0.90.40.00.5
Conditioned reinforcement - inactives4.95.67.62.61.92.42.70.22.72.42.8
Conditioned locomotion6.98.312.02.82.92.93.5-1.03.32.53.4
Intermittent access intake day 1-15 change1.11.12.11.10.50.91.5-0.51.21.01.4
Intermittent access intake escalation1.31.32.11.30.71.11.5-0.11.21.21.4
Intermittent access intake escalation 20.50.51.00.70.20.61.0-0.40.80.61.0
Intermitt. access day 1 inactive lever presses1.21.31.81.31.01.21.30.21.21.21.3
Intermitt. access day 15 inactive lever presses2.12.32.81.71.41.61.50.71.51.71.7
Intermitt. access escalation Index2.01.82.91.51.21.41.7-0.21.41.31.6
Intermittent access day 1 total infusions4.04.56.82.51.72.21.82.31.82.61.9
Intermittent access day 15 total infusions7.07.910.43.22.23.03.01.22.93.23.1
Intermittent access terminal intake (last 3 days)5.15.57.52.71.92.52.41.42.32.72.5
Intermittent access total infusions3.33.65.32.31.42.01.91.51.82.32.0
Intermittent access day 1 locomotion1.51.53.31.50.71.10.91.80.81.61.0
Intermittent access day 15 total locomotion4.34.56.02.41.52.22.30.82.42.42.4
Intermittent access total locomotion6.16.99.53.12.12.72.61.92.53.12.7
Intermittent access standard deviation0.60.71.10.90.60.81.0-0.10.80.81.0
Cocaine induced anxiety0.10.10.40.20.60.20.20.10.10.20.2
Post-drug Anxiety1.11.21.7-1.3-0.6-1.2-1.1-0.9-1.1-1.3-1.1
Baseline Anxiety2.72.93.9-1.8-2.0-1.9-1.5-1.0-1.6-1.8-1.7
Lifetime Intake2.52.84.12.01.31.81.71.41.52.01.7
Incentive Sensitization - Responses0.40.40.80.60.90.60.50.20.60.60.6
Incentive Sensitization - Breakpoint0.60.61.10.81.00.80.80.20.80.80.8
Progressive ratio test 1 active lever presses1.01.01.71.10.61.01.3-0.21.11.01.2
Progressive ratio test 1 breakpoint0.80.81.41.00.50.91.2-0.31.00.81.1
Progressive ratio test 1 inactive lever presses0.40.50.60.70.80.70.70.20.70.70.8
Progressive ratio test 2 active lever presses2.72.83.71.81.81.71.90.21.81.71.9
Progressive ratio test 2 breakpoint3.13.44.61.92.01.92.1-0.22.01.72.2
Progressive ratio test 2 inactive lever presses7.48.510.63.22.83.13.11.03.03.13.3
Total sessions with >9 infusions0.60.60.90.90.70.80.90.50.70.90.8
Short access day 1 total inactive lever presses2.12.43.01.71.11.71.70.51.71.71.7
Short access day 10 total inactive lever presses1.51.62.11.41.21.41.30.51.41.41.4
Short access day 1 total infusions1.92.12.81.71.51.51.41.11.21.71.4
Short access day 10 total infusions1.11.24.31.30.10.90.62.10.41.50.7
Short access total infusions0.60.61.41.00.40.70.61.20.41.10.6
Short access day 1 locomotion1.61.72.51.51.01.41.21.31.11.61.2
Short access day 10 total locomotion0.60.71.11.00.30.70.71.00.81.00.7
Short access total locomotion0.40.40.90.80.20.60.50.90.40.90.5
Compulsive drug intake4.24.16.0-2.4-1.4-2.1-2.2-1.2-1.9-2.4-2.2
One hour access (0.3 mA shock)6.98.010.33.12.73.03.10.72.93.03.2
One hour access (shock baseline)8.39.712.93.52.93.23.50.63.13.33.6
Number of responses in last shaping day0.50.50.80.60.90.70.8-0.20.70.60.8
Context. condit. distance diff. score0.80.91.31.10.91.01.00.40.81.11.1
Locomotion velocity, session 10.00.00.00.1-0.20.10.20.10.10.10.0
Locomotion distance, session 10.40.53.10.30.80.2-0.31.8-0.40.4-0.4
Locomotion velocity, session 22.22.53.5-1.7-1.2-1.8-1.8-0.1-1.9-1.6-1.8
Locomotion distance, session 20.30.41.2-0.30.3-0.4-0.61.1-0.8-0.2-0.8
Locomotion velocity, session 30.40.52.90.50.30.40.11.70.00.7-0.0
Locomotion distance, session 30.10.10.30.10.50.1-0.00.4-0.10.1-0.0
Stereotopy head waving bouts, day 30.50.72.40.90.50.70.31.50.41.00.4
Stereotopy head waving duration, day 31.11.31.91.30.91.21.01.21.01.41.0
Locomotion velocity, session 70.20.21.10.20.40.1-0.21.1-0.30.3-0.1
Locomotion distance, session 70.20.30.6-0.50.1-0.5-0.70.3-0.8-0.4-0.6
Stereotopy head waving bouts, day 71.01.12.11.20.91.10.81.50.91.30.8
Stereotopy head waving duration, day 70.40.52.4-0.2-0.5-0.2-0.61.5-0.50.0-0.7
Locomotion velocity, session 81.61.92.7-1.4-1.3-1.5-1.5-0.0-1.6-1.3-1.6
Locomotion distance, session 80.60.82.00.91.40.90.70.90.50.90.7
Degree of sensitization distance0.20.20.3-0.3-0.4-0.4-0.60.4-0.5-0.3-0.5
Degree of sensitization stereotypy0.10.21.00.10.20.1-0.11.0-0.10.2-0.3
Condit. Reinf. active minus inactive responses0.20.20.80.30.70.50.20.90.20.40.0
Condit. Reinf. active-inactive response ratio0.60.62.30.61.50.80.40.80.40.70.4
Condit. Reinf. active responses0.10.20.30.30.50.50.30.40.40.40.2
Condit. Reinf. inactive responses0.10.10.30.1-0.50.00.2-0.30.30.00.2
Incentive salience index mean0.20.20.60.30.70.40.20.80.10.40.0
Condit. Reinf. lever presses0.00.00.00.10.20.20.2-0.10.10.00.1
Time in familiar zone, hab. session 10.90.81.21.00.80.90.80.90.81.10.8
Time in novel zone, hab. session 10.30.30.5-0.5-0.7-0.5-0.4-0.6-0.4-0.5-0.4
Total zone transitions, hab. session 10.20.31.2-0.11.1-0.1-0.40.8-0.4-0.1-0.4
Total locomotion distance, hab. session 11.31.94.81.42.21.41.20.81.21.31.2
Locomotion velocity, hab. session 10.71.03.10.91.81.00.80.50.80.90.8
Time in familiar zone, hab. session 20.90.91.4-1.1-1.2-1.0-0.8-0.9-0.7-1.1-0.8
Time in novel zone, hab. session 20.30.31.40.60.20.40.21.20.10.70.2
Total zone transitions, hab. session 21.01.26.6-0.10.1-0.3-1.02.6-1.10.2-1.0
Total locomotion distance, hab. session 20.50.72.80.80.80.70.31.70.20.90.3
Locomotion velocity, hab. session 20.81.12.81.11.21.00.61.70.61.20.6
Novel to familiar place preference ratio0.20.20.4-0.2-0.3-0.3-0.50.6-0.5-0.1-0.4
Novelty place preference0.10.10.50.1-0.1-0.0-0.20.7-0.20.2-0.1
Time in novel zone, NPP test0.10.10.60.1-0.1-0.0-0.20.7-0.30.2-0.2
Total zone transitions, NPP test0.50.71.9-0.4-0.1-0.6-1.01.4-1.0-0.3-1.0
Total locomotion distance, NPP test0.20.30.90.60.50.50.30.90.30.70.3
Locomotion velocity, NPP test0.20.30.60.60.50.50.40.80.30.60.4
Pavlov. Cond. lever latency0.10.10.30.1-0.20.10.4-0.50.40.10.3
Pavlov. Cond. magazine entry latency0.30.41.80.6-0.00.40.11.30.10.70.2
Pavlov. Cond. change in total contacts0.70.81.11.00.51.00.80.90.81.00.8
Pavlov. Cond. index score0.20.20.30.50.50.50.40.40.40.50.4
Pavlov. Cond. latency score0.10.20.30.50.40.40.20.60.20.50.3
Pavlov. Cond. lever contacts0.10.10.20.30.40.20.00.50.00.20.1
Pavlov. Cond. magazine entry number0.10.10.1-0.30.0-0.3-0.30.0-0.3-0.3-0.4
Pavlov. Cond. intertrial magazine entries0.10.20.70.1-0.40.10.4-0.80.5-0.00.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.40.40.40.30.40.30.40.3
Pavlov. Cond. response bias0.10.10.20.40.30.40.30.30.30.40.4
Bone: apparent density0.71.17.30.60.20.2-0.42.7-0.40.8-0.3
Bone surface1.01.86.9-0.5-0.0-0.8-1.52.6-1.5-0.2-1.5
Bone volume0.61.06.10.30.30.0-0.62.5-0.60.5-0.5
Bone: connectivity density1.11.76.7-0.5-0.3-0.7-1.42.6-1.4-0.1-1.4
Bone: cortical apparent density1.11.43.1-1.2-1.8-1.3-1.0-0.7-1.0-1.2-1.1
Bone: cortical area0.30.40.6-0.7-0.4-0.7-0.6-0.6-0.6-0.8-0.6
Bone: cortical porosity0.10.10.40.30.60.30.20.40.20.30.2
Bone: cortical porosity0.10.10.3-0.40.1-0.4-0.50.1-0.5-0.4-0.5
Bone: cortical thickness3.35.57.8-2.8-1.9-2.6-2.2-1.9-2.2-2.8-2.4
Bone: cortical thickness1.82.12.8-1.7-1.4-1.6-1.4-0.9-1.4-1.6-1.5
Bone: cortical tissue density1.31.73.6-1.4-1.9-1.4-1.1-0.8-1.1-1.3-1.2
Bone: elastic displacement0.50.63.8-0.40.4-0.10.2-2.00.3-0.60.3
Bone: elastic work1.41.93.0-1.6-0.3-1.4-1.4-1.3-1.3-1.7-1.4
Bone: endosteal estimation1.73.75.12.32.12.01.51.91.52.21.8
Bone: endosteal perimeter3.57.210.03.12.32.82.52.42.43.22.6
Bone: final force1.11.82.7-1.3-1.0-1.4-1.60.6-1.6-1.2-1.6
Bone: final moment0.91.52.3-1.2-0.8-1.3-1.50.5-1.5-1.1-1.5
Bone: marrow area1.83.85.12.32.12.01.51.91.52.21.8
Bone: maximum diameter0.20.30.50.60.50.50.60.00.70.50.6
Bone: maximum force0.81.44.4-0.6-0.0-0.8-1.42.1-1.4-0.3-1.4
Bone: maximum moment0.71.23.8-0.50.1-0.7-1.32.0-1.4-0.3-1.3
Bone: minimum diameter1.73.15.52.01.31.81.42.31.32.21.4
Bone: periosteal estimation0.20.50.90.80.90.70.50.70.50.80.6
Bone: periosteal perimeter0.20.40.90.80.10.60.51.00.40.80.5
Bone: post-yield work3.14.216.32.11.71.70.84.00.72.40.8
Bone: stiffness0.71.14.4-0.3-0.4-0.6-1.12.1-1.1-0.0-1.1
Bone: tissue strength1.01.02.01.01.41.00.90.90.81.00.8
Bone: trabecular number0.50.85.60.4-0.00.1-0.42.4-0.40.6-0.4
Bone: trabecular spacing0.20.21.6-0.20.1-0.1-0.0-1.3-0.0-0.40.2
Bone: trabecular thickness1.21.43.41.30.61.10.91.80.91.50.8
Bone: trabecular tissue density3.44.87.62.11.52.22.7-1.12.71.92.8
Breakpoint value in progressive ratio session1.92.23.0-1.5-1.5-1.6-1.60.0-1.7-1.4-1.7
Distance traveled before self-admin0.20.21.2-0.01.10.1-0.20.4-0.10.0-0.2
Distance traveled after self-admin0.10.10.20.20.50.40.00.40.30.30.1
Delta time in closed arm before/after self-admin1.01.01.4-1.1-0.1-1.1-1.0-0.8-1.1-1.2-1.0
Delta time in open arm before/after self-admin0.40.30.60.60.20.70.60.40.80.70.6
Diff in mean of infusions in LGA sessions0.40.40.6-0.8-0.3-0.7-0.6-0.4-0.7-0.7-0.7
Extinction: sum of active levers before priming2.22.23.9-1.5-0.5-1.4-2.00.6-1.9-1.3-1.9
Active lever presses in extinction session 61.31.32.1-1.4-0.3-1.0-1.1-1.2-0.9-1.5-1.1
Delta distance traveled before/after self-admin0.00.00.30.1-0.50.00.10.00.10.10.1
Delta ambulatory time before/after self-admin0.20.21.0-0.3-1.0-0.3-0.2-0.2-0.1-0.3-0.3
Time in closed arm before self-admin0.20.20.30.5-0.60.20.40.40.20.50.4
Time in closed arm after self-admin0.40.41.2-0.5-1.1-0.7-0.2-0.6-0.6-0.5-0.3
Time in open arm before self-admin0.30.30.4-0.60.5-0.4-0.6-0.4-0.5-0.6-0.5
Time in open arm after self-admin0.10.10.5-0.00.70.20.0-0.30.3-0.00.1
Sum of active levers in priming session hrs 5-60.70.73.5-0.9-0.3-0.3-0.3-1.90.2-1.0-0.3
Time to tail flick, vehicle, before self-admin0.60.62.6-0.1-1.1-0.3-0.61.6-0.50.1-0.7
Time to tail flick, vehicle, after self-admin1.82.02.9-1.4-1.2-1.4-1.70.4-1.6-1.3-1.7
Time to tail flick, test, before self-admin0.50.52.70.7-0.30.40.21.60.40.80.1
Time to tail flick, test, after self-admin0.40.42.1-0.4-1.4-0.5-0.4-0.1-0.4-0.4-0.4
Delta time to tail flick, vehicle, before/after SA0.70.71.1-1.0-0.3-0.8-1.1-0.3-0.8-0.9-1.0
Delta time to tail flick, test, before/after SA2.72.44.3-1.6-1.8-1.5-1.0-2.1-1.2-1.8-1.1
Ambulatory time before self-admin0.30.31.60.21.30.50.00.60.30.30.0
Ambulatory time after self-admin1.21.31.91.21.21.30.81.41.11.30.8
Total heroin consumption3.94.76.0-2.4-2.3-2.2-2.4-0.5-2.2-2.3-2.4
Area under the delay curve0.30.31.40.50.40.4-0.01.20.00.60.1
Delay disc. indifference point, 0s delay0.60.63.00.70.70.60.21.70.00.80.1
Delay disc. indifference point, 16s delay1.71.72.41.41.51.41.20.61.51.41.3
Delay disc. indifference point, 2s delay0.50.50.90.80.70.70.50.90.50.80.5
Delay disc. indifference point, 24s delay0.30.30.4-0.6-0.4-0.6-0.5-0.6-0.5-0.6-0.4
Delay disc. indifference point, 4s delay0.10.10.40.1-0.30.1-0.10.70.00.2-0.1
Delay disc. indifference point, 8s delay0.10.10.4-0.00.1-0.2-0.40.6-0.6-0.0-0.3
Delay discount exponential model param0.20.21.0-0.3-0.2-0.20.1-1.00.1-0.40.0
Delay discount hyperbolic model param0.20.21.0-0.3-0.1-0.20.1-1.00.0-0.40.0
Fecal boli incidents, locomotor time 10.10.10.20.4-0.10.20.40.20.10.30.3
Change in fecal boli incidents, locomotor task0.30.30.5-0.5-0.6-0.4-0.70.2-0.3-0.5-0.7
Time >=10cm from walls, locomotor time 12.02.03.81.70.81.41.11.91.11.81.1
Bouts of movement, locomotor time 11.61.82.3-1.4-1.5-1.5-1.2-1.1-1.4-1.5-1.2
Total resting periods, locomotor time 10.91.01.2-1.0-1.1-1.1-0.9-1.0-1.0-1.1-0.8
Rest time, locomotor task time 11.01.11.80.91.01.11.2-1.01.20.71.3
Distance moved, locomotor task time 10.20.21.40.2-0.10.2-0.11.20.10.4-0.2
Vertical activity count, locomotor time 11.11.21.51.21.11.11.10.81.01.21.1
Time >=10cm from walls, locomotor time 20.10.10.20.10.00.10.3-0.40.30.10.3
Bouts of movement, locomotor time 20.60.60.8-0.9-0.8-0.8-0.8-0.4-0.8-0.8-0.8
Total resting periods, locomotor time 20.20.20.4-0.5-0.5-0.5-0.5-0.1-0.6-0.5-0.5
Rest time, locomotor task time 22.42.83.81.91.41.91.61.21.51.91.7
Distance moved, locomotor task time 20.91.01.6-1.2-0.5-1.1-1.0-1.0-0.8-1.3-1.0
Vertical activity count, locomotor time 20.70.83.4-0.9-0.0-0.8-0.3-1.9-0.3-1.1-0.4
Weight adjusted by age1.21.31.8-1.3-0.6-1.3-1.3-0.3-1.3-1.3-1.3
Seeking ratio, delayed vs. immediate footshock0.20.20.90.1-0.3-0.2-0.21.0-0.60.2-0.3
Locomotion in novel chamber5.36.58.72.91.92.72.90.92.72.82.9
Locomotion in novel chamber post-restriction2.83.44.72.02.01.92.10.11.71.92.2
Progressive ratio1.71.94.3-0.8-1.4-1.0-1.62.1-1.5-0.4-1.6
Food seeking constrained by brief footshock0.30.40.8-0.7-0.7-0.6-0.90.0-0.4-0.6-0.8
Seeking ratio, punishment vs. effort1.01.22.90.50.90.81.1-1.71.40.31.2
Run reversals in cocaine runway, females0.80.81.6-0.6-0.9-0.7-1.11.3-0.9-0.3-1.0
Run reversals in cocaine runway, males0.40.41.2-0.6-0.6-0.6-0.1-1.1-0.5-0.7-0.3
Latency to leave start box in cocaine runway0.50.61.80.70.90.70.11.30.30.80.3
Latency to leave start box in cocaine runway, F0.30.31.20.50.60.40.01.10.10.60.2
Latency to leave start box in cocaine runway, M0.00.00.10.20.20.30.00.20.30.20.1
Cd content in liver1.11.22.11.10.61.11.4-0.41.41.01.4
Co content in liver0.30.41.60.0-0.40.20.8-1.30.8-0.00.6
Cu content in liver0.20.20.4-0.50.6-0.3-0.5-0.3-0.4-0.5-0.4
Fe content in liver0.10.10.50.00.70.10.10.20.00.0-0.1
K content in liver0.60.62.3-0.30.5-0.3-0.81.5-0.7-0.1-0.9
Mg content in liver1.41.55.31.01.51.00.42.30.31.20.4
Mn content in liver0.70.81.5-1.0-0.3-0.9-1.20.3-0.9-0.9-1.2
Na content in liver0.20.20.8-0.30.9-0.1-0.1-0.5-0.2-0.3-0.1
Rb content in liver2.12.63.91.80.81.71.51.81.52.01.4
Se content in liver0.60.72.40.71.50.70.31.10.30.70.4
Sr content in liver2.62.43.1-1.7-1.1-1.7-1.6-1.0-1.6-1.8-1.6
Zn content in liver0.50.60.9-0.90.1-0.7-1.0-0.1-0.9-0.8-0.9