Nif3l1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio ENSRNOT00000058667 0.04 0.02 2.5e-04 0.03 0.03 0.03 0.04 1.0e-04 2.7e-04 1.9e-04 6.3e-05
2 Adipose intron excision ratio chr9:59991407:59993506 0.05 0.03 5.4e-05 0.05 0.04 0.04 0.05 3.3e-06 2.7e-05 1.9e-05 6.9e-06
3 BLA gene expression ENSRNOG00000013446 0.06 0.04 3.2e-03 0.06 0.05 0.05 0.06 2.6e-04 9.9e-04 1.4e-03 6.3e-04
4 Brain gene expression ENSRNOG00000013446 0.04 0.03 2.3e-03 0.03 0.02 0.02 0.03 7.9e-04 2.8e-03 9.9e-03 1.5e-03
5 Brain intron excision ratio chr9:59991407:59991902 0.06 0.04 2.3e-04 0.02 0.04 0.03 0.03 7.7e-03 2.4e-04 7.7e-04 1.1e-03
6 Brain intron excision ratio chr9:59991407:59993506 0.11 0.07 5.0e-06 0.06 0.04 0.04 0.04 1.3e-06 1.1e-04 2.8e-04 4.5e-05
7 Liver alternative TSS ENSRNOT00000018014 0.03 0.02 1.9e-03 0.01 0.02 0.01 0.01 1.0e-02 5.5e-03 8.2e-03 8.3e-03
8 Liver alternative TSS ENSRNOT00000058667 0.03 0.02 1.8e-03 0.01 0.02 0.01 0.01 9.8e-03 5.0e-03 7.4e-03 7.3e-03
9 Liver isoform ratio ENSRNOT00000018014 0.07 0.04 2.3e-05 0.03 0.03 0.03 0.02 1.0e-04 1.9e-04 1.6e-04 1.0e-03
10 Liver isoform ratio ENSRNOT00000058667 0.09 0.05 1.1e-06 0.04 0.04 0.04 0.04 9.7e-06 4.1e-05 3.0e-05 4.8e-05
11 OFC intron excision ratio chr9:59991407:59993506 0.3 0.16 4.4e-03 0.05 0.04 0.05 0.05 2.2e-02 3.4e-02 3.0e-02 2.2e-02
12 PL gene expression ENSRNOG00000013446 0.11 0.06 9.6e-07 0.06 0.08 0.07 0.06 3.0e-05 1.7e-06 2.3e-06 1.4e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.72.413.62.3-0.40.6-3.70.6-0.41.7-1.7-0.50.5-0.3-1.7
BMI without tail1.12.23.6-0.11.61.8-1.3-1.51.61.9-1.91.5-1.51.80.0
Body weight0.20.91.9-0.91.21.01.0-0.91.20.1-0.11.0-1.01.40.5
Epididymis fat weight1.33.17.7-1.51.32.61.7-1.71.31.6-1.61.3-1.31.52.8
Glucose0.40.72.51.1-0.50.4-1.60.5-0.51.0-1.1-0.60.6-0.7-0.1
Heart weight0.91.22.2-0.91.2-0.60.7-0.41.2-1.31.41.2-1.21.2-1.5
Left kidney weight0.00.10.3-0.10.10.10.40.30.1-0.50.5-0.00.00.2-0.5
Right kidney weight0.10.40.7-0.60.70.40.6-0.40.7-0.60.60.7-0.70.8-0.4
Tail length2.06.125.1-3.62.10.95.0-2.02.1-1.11.12.0-2.02.22.7
Length with tail1.97.131.4-3.92.10.85.6-1.92.1-1.61.72.0-2.02.22.7
Length without tail0.40.94.1-0.8-0.3-0.62.00.4-0.3-1.61.6-0.40.4-0.40.5
Liver weight, left1.21.93.1-1.41.51.81.1-1.61.51.0-0.91.4-1.41.31.6
Liver weight, right1.72.95.1-2.11.7-0.92.1-0.81.7-2.22.31.6-1.61.6-0.7
Parametrial fat weight0.20.41.4-0.10.11.20.1-0.50.11.0-1.00.1-0.10.21.0
Retroperitoneal fat weight0.31.02.1-0.30.81.5-0.2-1.10.81.4-1.40.7-0.70.91.1
Intraocular pressure2.43.37.62.5-2.0-1.2-2.81.9-2.00.5-0.5-1.91.9-1.9-1.5
Extensor digitorum longus weight0.52.06.61.7-0.71.4-2.60.5-0.72.3-2.3-0.70.7-0.60.1
Soleus weight0.30.92.0-0.81.30.90.0-0.81.30.2-0.11.2-1.21.4-0.3
Tibialis anterior weight0.00.10.20.4-0.30.2-0.40.3-0.30.4-0.4-0.40.4-0.30.2
Tibia length1.13.013.4-2.61.20.23.7-0.91.2-1.81.81.1-1.11.21.4
Number of licking bursts0.40.41.3-0.1-0.2-1.10.30.6-0.2-1.11.1-0.30.3-0.2-0.7
Food consumed during 24 hour testing period0.80.93.31.3-1.0-0.3-1.80.8-1.00.5-0.5-0.80.8-0.9-0.7
Times rat made contact with spout0.60.62.90.9-0.60.4-1.70.1-0.61.1-1.1-0.40.4-0.30.1
Mean time between licks in bursts1.52.06.90.30.02.4-0.6-0.80.02.6-2.60.1-0.10.02.0
Mean num. licks in bursts0.91.13.90.9-0.41.3-1.5-0.3-0.42.0-2.0-0.20.2-0.30.7
Std. dev. time between licks in bursts0.40.51.51.0-0.70.2-1.20.5-0.70.8-0.8-0.60.6-0.6-0.2
Water consumed over 24 hours2.02.46.82.0-1.4-1.3-2.61.6-1.4-0.10.0-1.31.3-1.2-2.1
Indifference point 0 sec0.50.81.31.0-1.1-0.6-0.61.1-1.1-0.20.2-1.01.0-1.1-0.7
Indifference point AUC0.40.51.2-0.1-0.4-1.00.80.8-0.4-1.11.1-0.50.5-0.7-0.3
Indifference point function ln k0.30.40.7-0.30.30.7-0.3-0.80.30.7-0.70.8-0.80.80.2
Indifference point function log k0.30.40.7-0.30.30.7-0.3-0.80.30.7-0.70.8-0.80.80.2
Delay discounting total patch changes 0 sec0.81.32.11.2-1.3-1.1-0.81.5-1.3-0.50.5-1.21.2-1.3-1.2
Delay discounting total patch changes 12 sec1.11.52.91.2-1.4-1.1-0.01.6-1.4-0.60.5-1.61.6-1.7-0.4
Delay discounting total patch changes 18 sec2.93.86.32.2-2.3-1.5-1.62.4-2.3-0.20.2-2.42.4-2.5-1.1
Delay discounting total patch changes 24 sec0.70.81.60.4-0.7-1.30.51.1-0.7-1.11.1-0.90.9-1.0-0.6
Delay discounting total patch changes 6 sec0.30.52.30.40.1-1.1-0.10.80.1-1.01.0-0.20.2-0.3-1.5
Delay discounting time to switch 0 sec0.10.10.30.40.3-0.0-0.50.00.30.2-0.20.0-0.00.1-0.5
Delay discounting water rate 0 sec0.10.10.4-0.5-0.10.40.5-0.3-0.10.0-0.00.3-0.30.10.6
Delay discounting water rate 12 sec0.71.02.1-0.91.3-0.1-0.1-1.01.3-0.40.41.4-1.41.5-0.9
Delay discounting water rate 18 sec0.50.62.0-0.3-0.2-1.40.20.4-0.2-1.41.40.0-0.0-0.0-1.1
Delay discounting water rate 24 sec0.91.33.1-1.21.40.80.2-1.31.4-0.10.11.6-1.61.7-0.1
Delay discounting water rate 6 sec0.10.20.5-0.30.40.4-0.3-0.50.40.3-0.20.7-0.70.6-0.1
Locomotor activity0.20.30.90.6-0.40.5-1.00.3-0.40.7-0.7-0.30.3-0.50.1
Locomotor testing distance0.50.73.11.2-0.7-0.3-1.80.9-0.70.3-0.3-0.60.6-0.7-1.1
Locomotor testing rearing0.00.10.30.0-0.10.4-0.5-0.1-0.10.3-0.30.1-0.1-0.00.2
Light reinforcement 11.32.310.72.0-0.81.1-3.30.5-0.82.0-2.0-0.90.9-0.8-0.5
Light reinforcement 20.30.40.8-0.30.80.90.4-0.60.80.5-0.50.6-0.60.70.3
Reaction time number correct0.30.41.80.20.2-0.8-1.00.30.2-0.60.60.1-0.1-0.1-1.4
Reaction time mean minus median0.00.00.0-0.10.0-0.1-0.1-0.10.0-0.20.20.1-0.10.1-0.1
Reaction time mean minus median AUC0.40.61.40.4-0.6-1.2-0.40.8-0.6-0.90.9-0.60.6-0.6-0.9
Reaction time num false alarms1.01.33.91.2-0.61.4-1.70.0-0.62.0-2.0-0.50.5-0.40.7
Reaction time num false alarms AUC1.01.44.21.2-0.51.4-1.70.0-0.52.1-2.1-0.50.5-0.40.7
Reaction time trials correct on left0.30.41.80.20.2-0.8-1.00.30.2-0.60.60.1-0.1-0.1-1.4
Reaction time trials on left0.20.31.70.20.2-0.8-1.00.30.2-0.60.60.1-0.1-0.0-1.3
Reaction time mean0.60.84.4-0.8-0.31.01.8-0.7-0.30.5-0.50.0-0.00.12.1
Reaction time mean AUC0.50.73.8-0.5-0.40.91.5-0.5-0.40.5-0.5-0.20.2-0.11.9
Median of all reaction times1.01.47.3-0.8-0.51.22.2-0.7-0.50.7-0.6-0.10.1-0.12.7
Reaction time omissions0.20.31.2-0.50.30.90.5-0.60.30.5-0.50.3-0.30.21.1
Reaction time false alarm rate0.91.34.20.8-0.41.7-0.9-0.2-0.42.1-2.1-0.40.4-0.21.3
Reaction time premature initiation rate1.52.04.20.7-1.0-2.0-0.21.6-1.0-1.91.9-1.01.0-0.9-2.0
Reaction time premature initiations1.62.26.70.8-0.8-2.2-0.81.7-0.8-2.02.0-0.80.8-0.9-2.6
Std. dev. reaction times0.20.31.0-0.80.50.21.0-0.50.5-0.40.40.5-0.50.50.6
Reaction time trials completed0.20.31.70.20.2-0.8-1.00.30.2-0.60.60.1-0.1-0.0-1.3
Reaction time trials AUC0.20.31.20.20.1-0.7-0.90.30.1-0.50.50.0-0.0-0.1-1.1
Social response proportion1.01.01.8-1.41.20.51.2-1.01.2-0.50.61.2-1.21.20.3
Social responses0.50.61.5-1.10.70.81.2-0.60.7-0.30.30.6-0.60.61.0
Social time0.10.10.5-0.6-0.0-0.00.7-0.2-0.0-0.50.50.3-0.30.20.2
Conditioned locomotion1.11.32.4-1.21.11.50.9-1.31.10.8-0.81.1-1.11.01.5
Cocaine response after cond. corrected1.41.62.9-1.61.21.11.7-1.61.20.2-0.11.4-1.41.31.2
Cocaine response after cond. not corrected2.12.34.6-2.01.6-0.12.1-1.31.6-1.41.41.7-1.71.6-0.0
Cocaine response before conditioning2.22.78.6-0.20.2-2.50.31.10.2-2.92.9-0.10.1-0.1-2.7
Saline control response0.30.41.0-0.40.6-0.50.2-0.20.6-0.80.80.6-0.60.8-1.0
Condit. Reinf. active minus inactive responses1.41.74.7-1.50.9-1.22.1-0.30.9-2.22.20.8-0.80.8-0.5
Condit. Reinf. active-inactive response ratio1.71.86.0-0.4-0.3-2.21.40.9-0.3-2.42.4-0.30.3-0.3-1.2
Condit. Reinf. active responses0.91.33.7-1.40.6-0.91.8-0.20.6-1.91.90.6-0.60.5-0.2
Condit. Reinf. inactive responses0.10.20.4-0.60.40.50.3-0.40.4-0.00.10.4-0.40.20.5
Condit. Reinf. lever presses1.82.55.31.0-1.4-2.3-0.52.0-1.4-1.81.7-1.61.6-1.7-1.6
Condit. Reinf. lever reinforcers received0.91.34.3-1.30.5-1.11.8-0.00.5-2.12.10.5-0.50.4-0.3
Pavlov. Cond. lever latency2.23.05.8-1.11.92.40.4-2.01.91.8-1.71.8-1.81.81.4
Pavlov. Cond. magazine entry latency1.72.03.41.4-1.8-1.4-0.61.6-1.8-0.50.5-1.91.9-1.8-0.4
Pavlov. Cond. change in total contacts1.72.33.40.5-1.8-1.81.11.7-1.8-1.61.6-1.71.7-1.70.1
Pavlov. Cond. index score2.43.14.81.3-2.1-2.1-0.12.1-2.1-1.41.3-2.22.2-2.2-0.6
Pavlov. Cond. latency score2.43.04.61.2-2.0-2.1-0.12.1-2.0-1.31.3-2.12.1-2.1-0.6
Pavlov. Cond. lever contacts2.33.25.91.0-1.9-2.4-0.12.1-1.9-1.91.9-1.81.8-1.9-1.3
Pavlov. Cond. magazine entry number1.31.62.8-1.01.51.40.1-1.51.50.7-0.71.7-1.71.70.1
Pavlov. Cond. intertrial magazine entries1.11.42.9-1.11.60.50.1-1.21.6-0.20.31.7-1.71.7-0.8
Pavlov. Cond. lever-magazine prob. diff.2.33.04.81.2-2.0-2.00.02.1-2.0-1.31.3-2.22.2-2.2-0.4
Pavlov. Cond. response bias1.72.44.11.0-1.7-2.0-0.01.8-1.7-1.51.4-1.71.7-1.7-0.8
Conditioned reinforcement - actives0.20.20.40.4-0.30.30.20.3-0.30.4-0.4-0.60.6-0.50.5
Conditioned reinforcement - inactives0.80.92.00.2-1.30.51.00.6-1.30.3-0.3-1.11.1-1.31.4
Conditioned locomotion0.10.10.70.40.20.3-0.80.10.20.5-0.5-0.10.10.0-0.1
Intermittent access intake day 1-15 change1.01.05.10.50.1-1.5-0.60.60.1-1.31.3-0.00.00.2-2.3
Intermittent access intake escalation1.31.35.50.5-0.1-1.8-0.40.8-0.1-1.71.7-0.20.2-0.0-2.3
Intermittent access intake escalation 21.11.13.5-0.30.6-1.40.40.10.6-1.61.60.6-0.60.7-1.9
Intermitt. access day 1 inactive lever presses1.82.03.71.6-1.9-0.2-1.21.3-1.90.7-0.7-1.71.7-1.90.1
Intermitt. access day 15 inactive lever presses0.20.20.50.0-0.2-0.60.30.5-0.2-0.70.7-0.20.2-0.2-0.5
Intermitt. access escalation Index1.41.23.30.5-0.71.7-0.3-0.2-0.71.8-1.8-0.50.5-0.61.7
Intermittent access day 1 total infusions0.50.61.10.6-0.90.50.10.4-0.90.7-0.8-0.90.9-1.10.9
Intermittent access day 15 total infusions1.01.11.81.1-1.2-0.9-0.21.3-1.2-0.60.5-1.31.3-1.3-1.0
Intermittent access terminal intake (last 3 days)1.41.62.41.2-1.3-1.4-0.61.5-1.3-0.80.8-1.41.4-1.5-1.3
Intermittent access total infusions1.01.12.31.1-1.3-0.5-0.31.2-1.3-0.10.0-1.41.4-1.5-0.2
Intermittent access day 1 locomotion2.32.45.21.6-2.1-0.2-0.51.5-2.10.4-0.4-2.12.1-2.30.4
Intermittent access day 15 total locomotion1.01.01.80.9-1.3-0.8-0.21.2-1.3-0.60.6-1.31.3-1.3-0.6
Intermittent access total locomotion0.80.91.91.0-1.20.0-0.40.9-1.20.4-0.4-1.31.3-1.40.3
Intermittent access standard deviation1.71.82.71.4-1.6-1.5-0.71.5-1.6-0.70.7-1.51.5-1.7-1.3
Cocaine induced anxiety0.10.10.3-0.10.40.5-0.4-0.30.40.5-0.50.4-0.40.40.0
Post-drug Anxiety0.50.61.4-0.60.90.2-0.2-0.80.90.3-0.31.2-1.21.0-0.3
Baseline Anxiety0.10.10.6-0.60.1-0.30.7-0.40.1-0.40.40.3-0.30.20.3
Lifetime Intake0.80.91.81.1-1.2-0.0-0.60.9-1.20.3-0.4-1.21.2-1.4-0.0
Incentive Sensitization - Responses0.30.31.4-0.2-0.50.80.6-0.0-0.50.6-0.6-0.20.2-0.51.2
Incentive Sensitization - Breakpoint0.40.41.6-0.1-0.50.80.5-0.1-0.50.7-0.7-0.20.2-0.51.2
Progressive ratio test 1 active lever presses2.02.03.91.6-1.9-0.3-0.61.6-1.90.1-0.1-2.02.0-2.0-0.1
Progressive ratio test 1 breakpoint1.92.03.51.6-1.8-0.7-0.51.6-1.8-0.30.3-1.91.9-1.9-0.6
Progressive ratio test 1 inactive lever presses4.14.47.52.7-2.50.4-2.41.7-2.51.7-1.8-2.42.4-2.60.1
Progressive ratio test 2 active lever presses1.11.22.71.0-1.6-0.1-0.21.1-1.60.1-0.1-1.41.4-1.70.1
Progressive ratio test 2 breakpoint1.61.73.81.4-1.9-0.4-0.61.4-1.90.0-0.0-1.61.6-1.9-0.3
Progressive ratio test 2 inactive lever presses1.61.94.01.4-1.90.1-1.01.2-1.90.7-0.8-1.71.7-2.00.5
Total sessions with >9 infusions1.41.52.71.6-1.4-0.2-1.61.2-1.40.5-0.5-1.51.5-1.5-0.4
Short access day 1 total inactive lever presses0.00.00.1-0.10.00.3-0.1-0.10.00.3-0.30.3-0.3-0.00.2
Short access day 10 total inactive lever presses0.10.10.40.1-0.30.1-0.1-0.1-0.30.6-0.60.0-0.0-0.20.5
Short access day 1 total infusions0.70.71.21.1-0.9-0.5-1.00.9-0.90.0-0.0-1.01.0-1.0-0.7
Short access day 10 total infusions0.20.20.40.6-0.5-0.3-0.00.5-0.5-0.00.0-0.60.6-0.6-0.3
Short access total infusions0.80.91.51.2-1.10.1-1.10.7-1.10.6-0.6-1.11.1-1.2-0.1
Short access day 1 locomotion3.13.36.41.9-2.4-0.8-0.52.1-2.4-0.0-0.0-2.52.5-2.5-0.1
Short access day 10 total locomotion1.01.12.11.0-1.2-0.9-0.31.2-1.2-0.50.5-1.51.5-1.4-0.4
Short access total locomotion0.80.81.51.1-1.0-0.2-0.90.9-1.00.4-0.4-1.21.2-1.20.0
Compulsive drug intake1.11.12.20.8-1.2-1.00.11.2-1.2-0.70.7-1.51.5-1.3-0.4
One hour access (0.3 mA shock)2.83.36.01.6-2.4-1.30.12.0-2.4-0.90.8-2.42.4-2.5-0.6
One hour access (shock baseline)0.30.40.80.6-0.8-0.10.20.6-0.80.0-0.1-0.80.8-0.90.1
Number of responses in last shaping day1.11.12.00.9-1.2-1.0-0.41.4-1.2-0.70.7-1.41.4-1.3-0.8
Context. condit. distance diff. score0.20.20.60.7-0.4-0.3-0.8-0.0-0.40.5-0.6-0.40.4-0.30.1
Locomotion velocity, session 10.70.72.30.8-0.30.7-1.2-0.2-0.31.5-1.5-0.40.4-0.60.7
Locomotion distance, session 10.30.31.90.30.40.0-1.4-0.40.40.5-0.50.4-0.40.5-0.7
Locomotion velocity, session 20.40.51.10.00.60.9-0.8-0.70.61.0-1.00.5-0.50.60.4
Locomotion distance, session 21.52.24.4-0.41.42.1-1.1-1.51.41.8-1.81.4-1.41.60.7
Locomotion velocity, session 30.50.61.4-0.00.70.9-0.5-0.90.71.2-1.20.6-0.60.80.5
Locomotion distance, session 30.40.40.6-0.60.70.60.5-0.80.70.3-0.30.7-0.70.70.6
Stereotopy head waving bouts, day 31.01.31.81.3-1.3-0.9-1.21.3-1.3-0.10.1-1.31.3-1.3-0.8
Stereotopy head waving duration, day 30.60.72.61.2-0.5-0.6-1.60.8-0.50.1-0.2-0.60.6-0.6-1.3
Locomotion velocity, session 70.60.61.51.2-0.60.0-1.20.4-0.60.9-0.9-0.70.7-0.7-0.2
Locomotion distance, session 70.40.61.90.30.01.1-0.6-0.50.01.4-1.40.0-0.00.01.0
Stereotopy head waving bouts, day 70.91.01.6-1.31.1-0.41.1-0.81.1-1.11.11.1-1.11.1-0.3
Stereotopy head waving duration, day 70.80.91.7-1.01.3-0.10.3-1.01.3-0.50.51.3-1.31.2-0.6
Locomotion velocity, session 80.30.40.7-0.30.80.4-0.1-0.90.80.5-0.50.7-0.70.70.1
Locomotion distance, session 80.30.41.00.00.50.7-0.5-0.90.51.0-1.00.5-0.50.60.4
Degree of sensitization distance0.20.20.80.7-0.5-0.1-0.90.4-0.50.3-0.3-0.40.4-0.5-0.3
Degree of sensitization stereotypy2.52.84.6-2.02.10.81.4-2.02.1-0.30.32.1-2.12.10.5
Condit. Reinf. active minus inactive responses1.11.33.60.0-0.6-1.70.81.2-0.6-1.91.9-0.60.6-0.7-1.1
Condit. Reinf. active-inactive response ratio0.50.51.30.1-0.4-1.10.20.8-0.4-1.21.2-0.50.5-0.5-0.8
Condit. Reinf. active responses0.70.92.9-0.80.1-1.01.60.40.1-1.71.70.1-0.1-0.0-0.4
Condit. Reinf. inactive responses0.20.21.1-0.60.30.41.0-0.30.3-0.10.10.3-0.30.20.7
Incentive salience index mean1.51.86.0-0.3-0.5-2.01.41.2-0.5-2.42.4-0.50.5-0.6-1.1
Condit. Reinf. lever presses0.60.92.8-0.3-0.3-1.31.30.7-0.3-1.71.7-0.40.4-0.4-0.4
Time in familiar zone, hab. session 11.11.12.4-0.81.1-0.80.3-0.71.1-1.01.01.1-1.11.2-1.5
Time in novel zone, hab. session 11.01.02.20.7-1.10.6-0.10.6-1.10.9-0.9-1.11.1-1.21.5
Total zone transitions, hab. session 10.50.71.1-1.01.10.10.5-0.91.1-0.40.41.1-1.11.00.1
Total locomotion distance, hab. session 10.60.93.3-0.80.2-1.21.10.20.2-1.81.80.3-0.30.2-0.8
Locomotion velocity, hab. session 10.40.62.4-0.70.1-0.91.00.20.1-1.51.50.2-0.20.2-0.5
Time in familiar zone, hab. session 21.41.53.21.0-1.1-1.8-0.41.5-1.1-1.21.2-1.21.2-1.0-1.4
Time in novel zone, hab. session 20.80.82.2-0.10.51.5-0.4-0.80.51.4-1.40.5-0.50.31.0
Total zone transitions, hab. session 20.40.51.70.10.50.7-1.3-0.60.50.9-0.90.6-0.60.7-0.0
Total locomotion distance, hab. session 20.30.40.9-0.10.60.6-0.9-0.60.60.5-0.50.7-0.70.9-0.3
Locomotion velocity, hab. session 20.20.30.9-0.00.50.6-0.9-0.50.50.6-0.60.6-0.60.7-0.1
Novel to familiar place preference ratio0.30.30.4-0.20.70.7-0.6-0.60.70.6-0.60.6-0.60.60.1
Novelty place preference0.20.20.3-0.10.50.5-0.5-0.40.50.4-0.40.5-0.50.5-0.0
Time in novel zone, NPP test0.20.20.4-0.10.60.4-0.6-0.40.60.3-0.30.6-0.60.6-0.3
Total zone transitions, NPP test0.00.10.1-0.10.3-0.2-0.2-0.20.3-0.20.20.2-0.20.3-0.2
Total locomotion distance, NPP test0.50.72.70.3-0.1-1.3-0.60.6-0.1-1.21.2-0.10.10.0-1.6
Locomotion velocity, NPP test0.50.72.20.6-0.5-1.3-0.80.9-0.5-1.01.0-0.50.5-0.4-1.5
Pavlov. Cond. lever latency0.70.82.61.0-0.50.9-1.20.1-0.51.6-1.6-0.50.5-0.40.5
Pavlov. Cond. magazine entry latency1.31.76.1-0.5-0.2-1.91.20.9-0.2-2.52.5-0.20.2-0.3-1.4
Pavlov. Cond. change in total contacts1.11.24.2-0.40.2-1.60.70.60.2-2.12.10.1-0.10.1-1.5
Pavlov. Cond. index score1.31.65.8-0.6-0.1-1.91.30.7-0.1-2.42.4-0.20.2-0.2-1.2
Pavlov. Cond. latency score1.31.76.3-0.90.2-1.81.50.40.2-2.52.50.2-0.20.1-1.2
Pavlov. Cond. lever contacts0.80.93.2-0.3-0.0-1.50.80.5-0.0-1.81.8-0.10.1-0.2-1.1
Pavlov. Cond. magazine entry number0.81.03.80.6-0.11.4-1.1-0.5-0.12.0-2.0-0.10.1-0.01.0
Pavlov. Cond. intertrial magazine entries0.30.40.6-0.60.70.60.5-0.70.70.4-0.40.6-0.60.80.7
Pavlov. Cond. lever-magazine prob. diff.1.41.75.7-0.3-0.4-2.11.01.0-0.4-2.42.4-0.50.5-0.5-1.3
Pavlov. Cond. response bias1.11.34.7-0.4-0.3-1.71.20.8-0.3-2.22.2-0.30.3-0.4-0.9
Bone: apparent density2.13.44.7-2.22.1-0.51.6-1.22.1-2.02.12.1-2.12.2-1.3
Bone surface2.13.78.3-2.62.10.12.9-1.42.1-1.71.82.0-2.02.10.2
Bone volume2.03.35.8-2.42.0-0.22.3-1.32.0-1.91.92.0-2.02.1-0.4
Bone: connectivity density1.93.05.3-1.82.2-0.11.4-1.22.2-1.41.52.1-2.12.3-1.2
Bone: cortical apparent density5.47.011.53.3-3.4-0.8-2.72.7-3.41.2-1.3-3.23.2-3.4-0.2
Bone: cortical area0.50.81.40.2-1.1-0.11.11.0-1.1-0.30.3-1.21.2-1.11.1
Bone: cortical porosity1.11.25.4-1.50.5-0.42.3-0.30.5-1.41.40.5-0.50.60.7
Bone: cortical porosity1.61.76.9-1.80.8-0.52.6-0.40.8-1.71.80.8-0.80.90.5
Bone: cortical thickness1.72.95.21.8-2.3-0.3-0.81.9-2.30.5-0.6-2.32.3-2.30.6
Bone: cortical thickness1.72.03.31.5-1.6-1.6-1.11.8-1.6-0.70.7-1.61.6-1.5-1.3
Bone: cortical tissue density5.06.510.53.2-3.2-0.7-2.82.5-3.21.3-1.4-3.13.1-3.2-0.2
Bone: elastic displacement0.60.73.20.4-0.1-1.4-0.80.5-0.1-1.01.0-0.10.1-0.0-1.8
Bone: elastic work0.20.20.7-0.20.1-0.60.20.20.1-0.90.90.1-0.10.2-0.7
Bone: endosteal estimation1.02.17.5-1.91.0-0.62.7-0.51.0-2.02.10.9-0.91.00.1
Bone: endosteal perimeter1.22.46.3-2.21.6-0.02.5-1.11.6-1.51.61.5-1.51.50.4
Bone: final force0.30.42.3-0.5-0.2-0.11.50.5-0.2-0.80.9-0.30.3-0.20.6
Bone: final moment0.30.41.1-0.2-0.4-0.51.00.8-0.4-1.01.0-0.50.5-0.30.0
Bone: marrow area0.91.97.2-1.80.8-0.72.7-0.30.8-2.12.10.8-0.80.80.1
Bone: maximum diameter0.40.84.6-0.9-0.4-0.22.10.3-0.4-0.90.9-0.40.4-0.41.4
Bone: maximum force0.40.62.4-0.90.4-0.31.60.10.4-1.31.30.3-0.30.6-0.1
Bone: maximum moment0.30.62.0-0.50.2-0.61.00.40.2-1.41.40.2-0.20.4-0.8
Bone: minimum diameter0.40.72.4-0.3-0.6-0.51.60.9-0.6-1.11.1-0.70.7-0.50.5
Bone: periosteal estimation0.61.26.2-1.1-0.1-0.62.50.4-0.1-1.61.6-0.10.1-0.10.7
Bone: periosteal perimeter0.40.73.1-1.00.2-0.41.80.10.2-1.31.30.2-0.20.20.4
Bone: post-yield work0.20.31.80.2-0.0-0.6-0.40.5-0.0-0.70.80.1-0.10.0-1.4
Bone: stiffness1.11.76.6-1.91.10.52.6-0.91.1-0.91.01.1-1.11.21.0
Bone: tissue strength0.40.41.0-0.60.80.60.2-0.60.80.00.00.8-0.81.0-0.1
Bone: trabecular number2.94.57.5-2.52.60.11.8-1.82.6-1.61.62.6-2.62.7-0.9
Bone: trabecular spacing1.11.52.41.1-1.30.7-0.70.4-1.31.5-1.6-1.31.3-1.41.5
Bone: trabecular thickness1.01.22.1-0.91.0-0.70.3-0.41.0-1.41.41.2-1.21.2-1.4
Bone: trabecular tissue density1.92.65.41.2-2.3-0.9-0.11.7-2.3-0.10.1-2.22.2-2.30.7
Breakpoint value in progressive ratio session0.60.72.4-0.2-0.2-1.20.60.7-0.2-1.51.5-0.20.2-0.2-1.1
Distance traveled before self-admin1.51.63.5-1.81.3-0.21.9-0.81.3-1.31.31.3-1.31.30.1
Distance traveled after self-admin0.40.41.2-0.70.61.10.7-0.60.60.2-0.20.6-0.60.60.7
Delta time in closed arm before/after self-admin0.10.10.4-0.1-0.2-0.20.30.2-0.2-0.60.6-0.20.2-0.3-0.0
Delta time in open arm before/after self-admin1.11.04.4-1.50.5-0.72.1-0.30.5-1.31.30.5-0.50.50.6
Diff in mean of infusions in LGA sessions1.61.73.7-1.21.2-1.30.9-0.31.2-1.91.91.2-1.21.3-1.5
Extinction: sum of active levers before priming0.60.61.3-0.70.7-0.70.5-0.10.7-1.11.20.7-0.70.8-1.0
Active lever presses in extinction session 60.20.21.1-0.2-0.00.80.5-0.4-0.00.5-0.5-0.00.0-0.01.1
Delta distance traveled before/after self-admin0.50.51.40.9-0.40.8-1.20.2-0.41.1-1.1-0.40.4-0.50.1
Delta ambulatory time before/after self-admin1.21.32.31.3-1.01.2-1.10.4-1.01.5-1.5-1.01.0-1.00.8
Time in closed arm before self-admin0.80.93.6-1.30.9-0.31.9-0.60.9-0.80.80.9-0.91.00.3
Time in closed arm after self-admin1.01.02.1-1.31.0-0.41.5-0.81.0-1.01.01.0-1.01.10.0
Time in open arm before self-admin2.32.57.02.0-1.31.1-2.70.8-1.32.0-2.0-1.31.3-1.30.2
Time in open arm after self-admin0.30.30.90.0-0.70.00.60.4-0.7-0.10.1-0.70.7-0.80.9
Sum of active levers in priming session hrs 5-60.60.61.3-1.00.71.01.2-0.80.7-0.10.10.7-0.70.70.9
Time to tail flick, vehicle, before self-admin0.30.30.40.6-0.60.6-0.20.3-0.60.5-0.5-0.60.6-0.50.5
Time to tail flick, vehicle, after self-admin0.10.10.30.2-0.10.3-0.1-0.0-0.10.5-0.5-0.10.1-0.10.3
Time to tail flick, test, before self-admin0.50.51.6-0.00.01.20.1-0.50.01.1-1.10.0-0.00.01.3
Time to tail flick, test, after self-admin0.30.31.60.8-0.1-0.3-1.30.2-0.10.2-0.2-0.10.1-0.1-1.2
Delta time to tail flick, vehicle, before/after SA0.20.20.3-0.10.6-0.2-0.5-0.30.60.2-0.20.6-0.60.5-0.6
Delta time to tail flick, test, before/after SA1.21.14.51.0-0.6-1.4-1.21.0-0.6-0.90.9-0.60.6-0.6-2.1
Ambulatory time before self-admin2.22.33.9-2.01.90.51.4-1.51.9-0.60.61.9-1.92.00.3
Ambulatory time after self-admin0.20.21.3-0.30.41.10.0-0.40.40.4-0.40.4-0.40.40.5
Total heroin consumption0.20.20.60.2-0.4-0.50.30.6-0.4-0.80.8-0.40.4-0.3-0.6
Area under the delay curve0.20.20.6-0.40.30.8-0.0-0.50.30.4-0.40.4-0.40.20.5
Delay disc. indifference point, 0s delay0.50.53.70.80.20.3-1.9-0.00.20.7-0.70.1-0.10.0-0.9
Delay disc. indifference point, 16s delay0.40.40.8-0.90.4-0.00.8-0.50.4-0.70.70.8-0.80.5-0.2
Delay disc. indifference point, 2s delay0.40.42.60.30.40.3-1.6-0.30.40.6-0.60.4-0.40.3-0.6
Delay disc. indifference point, 24s delay0.10.10.2-0.3-0.20.10.10.1-0.2-0.50.50.2-0.2-0.2-0.2
Delay disc. indifference point, 4s delay0.30.31.70.5-0.10.5-1.3-0.2-0.10.8-0.8-0.10.1-0.30.1
Delay disc. indifference point, 8s delay1.01.11.9-1.30.81.41.3-1.20.80.3-0.31.0-1.00.81.4
Delay discount exponential model param0.10.20.50.4-0.3-0.7-0.10.5-0.3-0.20.2-0.40.4-0.2-0.4
Delay discount hyperbolic model param0.10.10.50.2-0.2-0.70.20.4-0.2-0.40.4-0.30.3-0.1-0.4
Fecal boli incidents, locomotor time 10.30.31.1-0.2-0.4-0.80.50.5-0.4-1.11.1-0.30.3-0.2-0.3
Change in fecal boli incidents, locomotor task0.10.10.30.3-0.20.6-0.40.0-0.20.4-0.4-0.10.1-0.30.0
Time >=10cm from walls, locomotor time 10.20.20.70.1-0.60.30.30.3-0.60.2-0.2-0.50.5-0.60.9
Bouts of movement, locomotor time 12.62.94.51.2-2.1-2.00.42.0-2.1-1.21.2-2.12.1-2.1-0.7
Total resting periods, locomotor time 13.94.37.81.9-2.8-2.0-0.22.4-2.8-0.70.7-2.72.7-2.8-0.5
Rest time, locomotor task time 14.75.29.42.8-3.0-0.3-0.62.1-3.01.4-1.4-3.13.1-2.90.7
Distance moved, locomotor task time 13.84.17.8-2.82.41.41.3-2.22.4-0.30.42.7-2.72.41.0
Vertical activity count, locomotor time 11.81.83.1-1.61.71.10.4-1.61.70.1-0.11.7-1.71.60.7
Time >=10cm from walls, locomotor time 21.31.43.3-0.51.31.8-0.6-1.31.31.4-1.31.1-1.11.30.8
Bouts of movement, locomotor time 20.10.10.5-0.30.2-0.1-0.0-0.20.2-0.30.30.6-0.60.2-0.7
Total resting periods, locomotor time 20.20.20.60.1-0.5-0.6-0.10.3-0.5-0.50.5-0.00.0-0.4-0.8
Rest time, locomotor task time 23.84.48.42.2-2.9-0.7-0.52.1-2.90.7-0.8-2.92.9-2.80.7
Distance moved, locomotor task time 21.61.93.6-1.61.80.90.6-1.41.8-0.10.21.9-1.91.70.1
Vertical activity count, locomotor time 20.91.01.60.11.21.0-1.2-0.81.20.9-0.91.0-1.01.0-0.7
Weight adjusted by age1.11.31.9-1.11.4-0.80.7-0.41.4-1.31.31.2-1.21.3-1.1
Seeking ratio, delayed vs. immediate footshock2.02.34.7-1.81.81.11.1-1.71.8-0.30.32.2-2.21.80.1
Locomotion in novel chamber2.42.913.31.6-0.9-2.3-1.71.6-0.9-1.61.6-0.80.8-0.8-3.6
Locomotion in novel chamber post-restriction0.70.81.60.1-1.3-1.2-0.10.9-1.3-1.11.1-0.40.4-0.9-0.9
Progressive ratio0.60.72.00.6-0.61.4-0.6-0.3-0.61.4-1.4-0.20.2-0.50.8
Food seeking constrained by brief footshock1.41.72.9-1.61.5-0.30.9-1.01.5-1.01.01.7-1.71.6-0.7
Seeking ratio, punishment vs. effort2.32.94.2-2.12.0-1.01.3-0.92.0-1.81.91.8-1.82.0-0.9
Run reversals in cocaine runway, females0.20.20.40.4-0.3-0.1-0.60.2-0.30.5-0.5-0.40.4-0.50.3
Run reversals in cocaine runway, males1.31.32.40.8-1.6-1.5-0.11.3-1.6-0.70.7-1.31.3-1.3-0.4
Latency to leave start box in cocaine runway1.61.75.82.0-1.00.2-2.40.8-1.01.3-1.3-1.21.2-1.3-0.7
Latency to leave start box in cocaine runway, F1.11.23.71.4-1.10.1-1.90.7-1.11.0-1.0-1.11.1-1.3-0.1
Latency to leave start box in cocaine runway, M0.70.74.41.0-0.0-1.0-0.80.7-0.0-0.60.6-0.30.3-0.1-2.1
Cd content in liver0.20.20.3-0.60.60.10.4-0.50.6-0.20.20.6-0.60.50.1
Co content in liver0.40.51.80.4-0.4-1.4-0.10.5-0.4-0.90.9-0.40.4-0.5-1.0
Cu content in liver0.10.10.3-0.1-0.4-0.00.60.4-0.4-0.20.2-0.40.4-0.50.5
Fe content in liver0.91.03.3-0.50.4-1.20.50.30.4-1.81.80.4-0.40.4-1.6
K content in liver0.20.20.8-0.1-0.5-0.00.70.2-0.5-0.10.1-0.50.5-0.40.9
Mg content in liver0.00.00.1-0.20.1-0.10.20.00.1-0.40.40.1-0.10.1-0.1
Mn content in liver2.52.94.42.1-2.1-1.4-1.71.8-2.10.1-0.1-2.12.1-2.0-0.9
Na content in liver0.40.41.5-0.4-0.4-0.61.20.4-0.4-1.01.0-0.40.4-0.50.2
Rb content in liver1.72.23.5-1.71.71.31.3-1.91.70.5-0.41.7-1.71.61.1
Se content in liver0.20.20.70.2-0.2-0.5-0.30.5-0.2-0.60.6-0.20.2-0.2-0.9
Sr content in liver1.81.62.21.2-1.50.7-0.70.8-1.51.3-1.3-1.51.5-1.51.2
Zn content in liver0.40.41.10.5-0.30.8-0.70.1-0.31.0-1.0-0.30.3-0.40.7