Csnk1e

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000013076 0.07 0.04 8.6e-07 0.05 0.03 0.03 0.04 2.1e-06 3.2e-04 3.3e-04 1.7e-05
2 BLA gene expression ENSRNOG00000013076 0.05 0.04 6.1e-03 0.01 0.02 0 0.01 1.3e-01 4.3e-02 1.9e-01 1.2e-01
3 BLA intron excision ratio chr7:110984354:110985397 0.09 0.06 1.4e-03 0.06 0.05 0.05 0.06 5.9e-04 9.4e-04 1.1e-03 2.4e-04
4 BLA intron excision ratio chr7:110984585:110985397 0.08 0.05 4.2e-03 0.05 0.04 0.05 0.06 1.6e-03 2.7e-03 1.7e-03 3.3e-04
5 Brain intron excision ratio chr7:110984354:110985397 0.14 0.06 9.9e-10 0.11 0.12 0.12 0.11 4.0e-10 7.5e-11 6.7e-11 1.1e-10
6 Brain intron excision ratio chr7:110984585:110985397 0.12 0.06 3.7e-08 0.1 0.09 0.11 0.1 1.0e-09 5.3e-09 1.5e-10 3.7e-09
7 IL isoform ratio ENSRNOT00000087800 0.31 0.13 6.0e-04 0.04 0.08 0.06 0.09 4.5e-02 5.0e-03 1.2e-02 3.6e-03
8 NAcc gene expression ENSRNOG00000013076 0.06 0.04 5.9e-04 0.02 0.03 0.03 0.03 1.3e-02 3.7e-03 4.5e-03 2.4e-03
9 NAcc intron excision ratio chr7:110984354:110985397 0.24 0.13 2.1e-06 0.1 0.09 0.09 0.11 7.6e-08 3.6e-07 2.5e-07 1.7e-08
10 NAcc intron excision ratio chr7:110984585:110985397 0.22 0.13 2.1e-05 0.09 0.07 0.06 0.1 4.6e-07 3.7e-06 1.4e-05 1.6e-07
11 PL isoform ratio ENSRNOT00000087800 0.04 0.03 7.4e-03 0.02 0.01 0.01 0.01 1.8e-02 6.1e-02 4.8e-02 8.8e-02
12 PL isoform ratio ENSRNOT00000088424 0.07 0.05 1.0e-03 0.03 0.01 0.01 0.01 3.1e-03 3.6e-02 4.8e-02 3.2e-02
13 PL intron excision ratio chr7:110984354:110985397 0.22 0.08 4.3e-11 0.18 0.16 0.18 0.18 2.2e-13 2.7e-12 1.9e-13 1.3e-13
14 PL intron excision ratio chr7:110984585:110985397 0.23 0.09 5.7e-11 0.17 0.16 0.18 0.18 2.8e-13 1.6e-12 2.3e-13 1.2e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.31.02.1-0.0-0.21.3-1.40.8-0.7-1.1-0.31.1-1.1-0.71.21.3-1.3
BMI without tail0.40.82.3-1.1-1.10.9-0.90.20.00.1-1.50.9-0.9-0.31.11.0-1.0
Body weight0.41.67.72.02.60.2-0.3-0.30.5-2.02.80.0-0.00.20.10.2-0.2
Epididymis fat weight0.30.85.21.11.50.10.1-0.20.2-1.32.30.3-0.2-0.20.20.0-0.1
Glucose0.71.02.9-0.00.8-0.90.7-1.61.70.50.6-1.11.01.4-1.0-0.80.8
Heart weight2.23.15.61.62.4-1.71.8-2.12.10.22.1-1.61.62.0-1.5-1.61.6
Left kidney weight1.95.625.04.24.20.4-0.40.8-1.0-3.85.00.4-0.4-0.90.30.4-0.4
Right kidney weight2.36.733.84.35.0-0.80.6-0.60.4-3.35.8-0.91.00.3-1.0-0.80.8
Tail length0.72.24.60.21.1-1.61.7-2.02.10.91.0-1.51.41.5-1.4-1.51.5
Length with tail1.03.713.62.63.5-1.41.3-1.51.6-1.13.7-1.31.31.3-1.4-1.31.3
Length without tail1.32.913.22.73.1-0.90.9-0.50.5-1.73.6-1.01.10.2-1.2-1.01.0
Liver weight, left1.11.84.01.51.11.2-1.21.4-1.1-2.01.21.3-1.3-1.11.41.3-1.3
Liver weight, right0.60.95.21.71.8-0.20.2-0.10.2-1.32.3-0.10.1-0.3-0.1-0.20.2
Parametrial fat weight1.42.75.80.31.0-1.81.8-1.92.01.60.9-1.61.62.4-1.7-1.61.6
Retroperitoneal fat weight0.93.116.03.13.5-0.30.3-0.40.5-2.04.0-0.30.30.8-0.3-0.30.3
Intraocular pressure0.40.51.00.80.50.7-0.60.8-0.9-1.00.80.5-0.5-0.70.50.6-0.6
Extensor digitorum longus weight0.41.77.2-1.8-2.01.0-1.00.6-0.50.5-2.70.8-0.9-1.11.01.0-1.0
Soleus weight1.33.87.7-1.0-0.0-2.11.9-2.22.12.4-0.1-2.02.12.8-2.1-1.92.0
Tibialis anterior weight0.93.013.5-3.4-3.40.4-0.5-0.0-0.01.9-3.70.2-0.2-0.80.30.4-0.4
Tibia length0.51.32.31.41.11.2-1.41.1-1.0-1.51.31.0-1.00.21.01.3-1.2
Number of licking bursts0.20.30.9-0.9-0.90.0-0.20.00.10.9-0.90.2-0.20.70.20.2-0.2
Food consumed during 24 hour testing period0.50.61.00.00.01.0-0.90.6-0.6-1.00.30.9-1.0-0.71.01.0-1.0
Times rat made contact with spout1.92.26.0-0.8-0.1-1.41.4-1.92.32.0-0.3-1.21.22.5-1.2-1.21.2
Mean time between licks in bursts1.62.33.5-0.0-0.81.7-1.91.9-1.7-0.9-1.41.7-1.7-1.11.71.7-1.7
Mean num. licks in bursts0.81.02.00.20.8-1.01.2-1.31.40.50.8-1.11.10.8-1.1-1.11.1
Std. dev. time between licks in bursts0.10.10.60.80.5-0.1-0.00.4-0.4-0.30.0-0.20.10.1-0.1-0.10.1
Water consumed over 24 hours0.30.30.8-0.30.0-0.70.5-0.70.90.6-0.2-0.50.50.8-0.6-0.70.6
Indifference point 0 sec1.11.72.50.50.9-1.61.5-1.41.50.90.3-1.51.51.4-1.4-1.51.5
Indifference point AUC0.40.41.7-1.3-1.30.1-0.10.3-0.40.7-1.30.1-0.1-0.30.00.1-0.1
Indifference point function ln k0.50.72.81.51.60.2-0.0-0.20.3-1.21.70.0-0.10.10.10.1-0.1
Indifference point function log k0.50.72.81.51.60.2-0.0-0.20.3-1.21.70.0-0.10.10.10.1-0.1
Delay discounting total patch changes 0 sec0.91.52.2-0.10.4-1.51.4-1.41.51.1-0.3-1.41.41.2-1.4-1.41.4
Delay discounting total patch changes 12 sec0.00.00.10.1-0.00.0-0.20.2-0.2-0.1-0.2-0.00.00.0-0.00.0-0.0
Delay discounting total patch changes 18 sec0.10.20.6-0.10.0-0.50.2-0.50.30.4-0.2-0.50.50.8-0.5-0.40.4
Delay discounting total patch changes 24 sec1.21.52.7-1.1-0.6-1.41.2-1.21.01.6-0.8-1.31.31.1-1.3-1.31.3
Delay discounting total patch changes 6 sec0.20.20.5-0.4-0.3-0.50.4-0.40.40.6-0.7-0.60.60.5-0.6-0.40.5
Delay discounting time to switch 0 sec1.32.02.90.5-0.31.6-1.61.7-1.7-1.70.01.5-1.5-1.61.61.5-1.5
Delay discounting water rate 0 sec2.84.57.20.71.5-2.42.2-2.32.41.70.9-2.32.32.7-2.4-2.32.3
Delay discounting water rate 12 sec0.61.03.8-0.10.5-0.70.7-1.51.81.0-0.2-0.70.61.9-0.6-0.60.6
Delay discounting water rate 18 sec1.21.54.90.91.4-1.21.1-1.31.40.80.8-1.11.12.2-1.1-1.11.1
Delay discounting water rate 24 sec1.42.05.01.72.2-1.11.1-1.41.6-0.22.0-1.21.21.6-1.1-1.11.1
Delay discounting water rate 6 sec2.13.06.9-0.30.6-1.81.6-2.22.51.90.2-1.71.72.6-1.7-1.71.7
Locomotor activity0.30.42.00.81.20.3-0.3-0.20.3-1.11.40.1-0.10.10.10.3-0.2
Locomotor testing distance0.20.41.5-1.2-0.5-0.30.3-0.91.00.8-0.5-0.40.40.7-0.4-0.30.4
Locomotor testing rearing0.20.20.80.20.30.6-0.70.2-0.1-0.90.60.5-0.5-0.20.50.5-0.5
Light reinforcement 10.10.30.40.40.00.6-0.60.6-0.5-0.5-0.30.6-0.6-0.30.60.6-0.6
Light reinforcement 20.50.71.20.1-0.11.0-0.90.6-0.6-1.0-0.21.0-1.0-1.11.11.0-1.0
Reaction time number correct0.30.41.3-1.1-1.20.3-0.30.3-0.20.8-1.00.5-0.5-0.10.50.4-0.4
Reaction time mean minus median0.00.00.10.20.2-0.10.10.0-0.1-0.30.3-0.20.2-0.3-0.2-0.10.1
Reaction time mean minus median AUC0.20.20.60.20.5-0.50.5-0.40.2-0.20.8-0.60.6-0.1-0.6-0.50.6
Reaction time num false alarms0.00.00.2-0.20.0-0.1-0.1-0.50.5-0.0-0.2-0.10.10.1-0.1-0.10.1
Reaction time num false alarms AUC0.00.10.2-0.3-0.2-0.20.1-0.50.40.1-0.3-0.10.1-0.0-0.1-0.20.2
Reaction time trials correct on left0.30.41.3-1.1-1.20.3-0.30.3-0.20.8-1.00.5-0.5-0.10.50.4-0.4
Reaction time trials on left0.40.51.6-1.2-1.30.4-0.40.3-0.30.8-1.10.6-0.6-0.20.60.5-0.5
Reaction time mean0.20.30.70.70.8-0.40.2-0.30.2-0.40.8-0.70.60.3-0.6-0.40.4
Reaction time mean AUC0.10.20.50.40.6-0.30.2-0.30.1-0.30.7-0.60.60.2-0.5-0.30.4
Median of all reaction times0.10.20.50.70.7-0.20.0-0.20.0-0.40.6-0.50.40.4-0.4-0.20.2
Reaction time omissions2.93.95.4-1.8-2.32.2-2.31.8-1.9-0.7-1.82.0-2.0-2.22.02.2-2.1
Reaction time false alarm rate0.10.10.40.10.3-0.40.3-0.60.5-0.10.1-0.50.40.0-0.4-0.40.4
Reaction time premature initiation rate0.10.10.50.50.60.1-0.00.1-0.3-0.50.70.3-0.30.10.30.2-0.2
Reaction time premature initiations0.00.00.2-0.10.10.00.10.0-0.2-0.00.40.2-0.20.10.20.1-0.1
Std. dev. reaction times0.20.31.10.50.8-0.40.4-0.40.2-0.41.1-0.60.5-0.0-0.5-0.40.5
Reaction time trials completed0.40.51.6-1.2-1.30.4-0.40.3-0.30.8-1.10.6-0.6-0.20.60.5-0.5
Reaction time trials AUC0.20.41.1-1.0-1.10.4-0.30.3-0.30.6-0.90.6-0.5-0.20.50.4-0.4
Social response proportion4.44.76.20.6-0.32.5-2.42.4-2.4-2.5-0.82.3-2.4-2.52.52.5-2.5
Social responses1.21.62.8-0.3-0.81.3-1.41.6-1.7-0.7-1.11.3-1.3-1.21.31.3-1.3
Social time0.81.14.0-1.4-1.70.9-0.90.6-0.50.5-2.00.8-0.9-0.40.90.9-0.9
Conditioned locomotion0.40.41.81.31.30.1-0.20.3-0.1-0.71.00.2-0.20.70.20.2-0.2
Cocaine response after cond. corrected1.01.21.90.80.31.1-1.01.3-1.1-1.10.31.4-1.4-0.81.41.2-1.2
Cocaine response after cond. not corrected0.91.01.70.3-0.01.2-1.11.1-0.9-1.0-0.11.3-1.3-0.91.31.2-1.2
Cocaine response before conditioning0.30.41.3-1.2-0.9-0.20.0-0.60.60.8-0.9-0.40.40.2-0.4-0.20.3
Saline control response0.30.40.90.30.6-0.70.5-0.50.6-0.10.2-0.90.90.0-0.9-0.70.8
Condit. Reinf. active minus inactive responses0.20.21.0-0.4-0.60.3-0.30.6-1.0-0.2-0.20.2-0.2-1.00.10.2-0.2
Condit. Reinf. active-inactive response ratio0.10.10.50.20.10.2-0.20.5-0.7-0.50.20.2-0.1-0.70.10.2-0.2
Condit. Reinf. active responses0.50.82.9-0.2-0.50.8-0.81.1-1.4-0.90.10.7-0.6-1.70.60.7-0.7
Condit. Reinf. inactive responses0.50.71.1-0.3-0.60.9-1.11.0-1.0-0.60.00.8-0.8-0.90.80.9-0.9
Condit. Reinf. lever presses0.40.50.9-0.9-0.7-0.70.6-0.60.30.9-0.5-0.90.90.0-0.9-0.80.8
Condit. Reinf. lever reinforcers received0.40.52.30.1-0.30.6-0.61.0-1.3-0.90.30.5-0.4-1.50.40.5-0.5
Pavlov. Cond. lever latency0.40.61.0-0.6-0.71.0-0.90.7-0.5-0.3-0.31.0-0.9-0.60.90.9-0.9
Pavlov. Cond. magazine entry latency0.50.61.0-0.8-0.7-0.80.8-0.70.41.0-1.0-0.90.80.3-0.8-0.80.8
Pavlov. Cond. change in total contacts0.70.94.72.22.0-0.30.10.1-0.3-1.01.5-0.40.30.6-0.3-0.20.2
Pavlov. Cond. index score0.60.71.40.20.3-1.10.9-0.80.50.7-0.1-1.21.20.7-1.1-1.01.1
Pavlov. Cond. latency score0.91.12.00.20.3-1.31.2-0.90.70.9-0.1-1.41.41.0-1.3-1.31.3
Pavlov. Cond. lever contacts0.60.81.40.40.7-1.11.0-0.90.80.60.2-1.21.10.9-1.1-1.11.1
Pavlov. Cond. magazine entry number0.60.81.6-0.1-0.11.1-1.00.8-0.5-0.7-0.01.3-1.3-0.61.21.1-1.1
Pavlov. Cond. intertrial magazine entries0.20.21.1-0.10.3-0.30.2-0.40.30.31.0-0.40.50.8-0.5-0.30.4
Pavlov. Cond. lever-magazine prob. diff.0.40.61.20.20.2-0.90.8-0.70.40.6-0.2-1.11.00.6-1.0-0.90.9
Pavlov. Cond. response bias0.10.10.40.40.3-0.50.4-0.30.10.1-0.0-0.60.50.3-0.5-0.40.4
Conditioned reinforcement - actives1.00.92.8-1.7-1.60.7-0.60.7-0.90.1-1.00.7-0.7-1.40.60.7-0.7
Conditioned reinforcement - inactives1.01.13.7-1.9-1.3-0.80.8-1.10.81.7-1.1-0.80.80.3-0.8-0.80.8
Conditioned locomotion1.01.24.4-1.3-1.01.0-0.90.8-0.9-1.0-0.71.1-1.1-2.10.91.0-1.0
Intermittent access intake day 1-15 change0.40.41.2-0.8-0.6-0.50.5-0.60.71.1-0.9-0.30.40.6-0.5-0.50.4
Intermittent access intake escalation0.50.51.4-1.1-0.9-0.40.4-0.70.71.2-1.1-0.20.30.5-0.3-0.30.3
Intermittent access intake escalation 20.60.61.4-0.9-0.5-0.70.7-1.01.01.2-0.7-0.60.60.8-0.7-0.70.7
Intermitt. access day 1 inactive lever presses0.40.41.21.11.0-0.50.4-0.30.1-0.21.1-0.70.60.4-0.4-0.50.5
Intermitt. access day 15 inactive lever presses0.20.20.50.40.4-0.50.4-0.30.10.20.7-0.30.40.6-0.4-0.40.4
Intermitt. access escalation Index0.30.30.9-0.7-0.90.5-0.50.3-0.40.3-1.00.5-0.5-0.10.40.5-0.5
Intermittent access day 1 total infusions1.61.84.3-0.6-0.81.4-1.31.3-1.5-1.4-0.11.4-1.4-2.11.31.4-1.4
Intermittent access day 15 total infusions0.40.51.0-1.0-1.00.6-0.60.4-0.5-0.2-0.70.7-0.7-0.90.60.6-0.6
Intermittent access terminal intake (last 3 days)0.40.40.8-0.8-0.90.6-0.60.6-0.7-0.2-0.60.6-0.6-0.90.50.6-0.6
Intermittent access total infusions1.51.73.3-0.9-1.21.4-1.31.3-1.5-1.0-0.61.4-1.4-1.81.31.3-1.4
Intermittent access day 1 locomotion0.20.21.1-0.5-0.30.4-0.40.3-0.4-0.6-0.10.4-0.5-1.10.40.4-0.4
Intermittent access day 15 total locomotion0.10.10.6-0.8-0.3-0.20.2-0.40.40.2-0.0-0.10.1-0.2-0.2-0.20.2
Intermittent access total locomotion0.10.10.4-0.40.1-0.30.3-0.60.5-0.10.5-0.10.1-0.3-0.3-0.20.2
Intermittent access standard deviation0.10.20.4-0.6-0.40.4-0.40.1-0.1-0.5-0.10.3-0.3-0.60.40.4-0.4
Cocaine induced anxiety0.20.20.80.60.60.2-0.20.2-0.2-0.90.60.1-0.2-0.70.20.2-0.2
Post-drug Anxiety1.71.86.52.52.5-1.01.0-0.30.4-0.92.2-1.01.00.7-0.9-1.01.0
Baseline Anxiety2.32.55.21.01.2-1.81.7-1.31.41.30.8-1.71.72.3-1.7-1.71.7
Lifetime Intake1.61.83.2-0.7-1.01.5-1.41.4-1.6-1.2-0.41.5-1.5-1.81.41.4-1.5
Incentive Sensitization - Responses0.70.71.7-0.9-0.6-0.90.8-1.10.81.3-0.2-0.70.80.6-0.8-0.80.8
Incentive Sensitization - Breakpoint0.70.71.6-1.0-0.6-0.90.8-1.10.81.3-0.1-0.80.80.5-0.8-0.80.8
Progressive ratio test 1 active lever presses0.60.71.2-0.9-1.00.7-0.70.8-1.0-0.3-0.50.9-0.9-1.10.60.7-0.8
Progressive ratio test 1 breakpoint0.20.30.5-0.6-0.70.4-0.30.5-0.7-0.1-0.30.5-0.5-0.70.30.4-0.4
Progressive ratio test 1 inactive lever presses0.70.71.7-1.3-1.30.7-0.60.5-0.9-0.2-1.00.6-0.7-1.30.60.7-0.7
Progressive ratio test 2 active lever presses0.40.42.2-1.5-1.2-0.30.3-0.40.11.0-0.5-0.10.2-0.1-0.3-0.30.3
Progressive ratio test 2 breakpoint0.20.21.0-1.0-0.9-0.10.1-0.1-0.20.6-0.20.1-0.1-0.2-0.1-0.00.0
Progressive ratio test 2 inactive lever presses0.50.63.0-1.7-1.70.1-0.1-0.0-0.31.0-1.20.2-0.1-0.30.00.1-0.1
Total sessions with >9 infusions0.20.20.5-0.10.00.4-0.30.3-0.4-0.60.50.4-0.4-0.70.30.4-0.4
Short access day 1 total inactive lever presses0.30.41.20.60.50.3-0.20.6-0.8-1.10.50.5-0.5-0.90.20.3-0.4
Short access day 10 total inactive lever presses2.93.25.31.62.2-1.81.7-1.81.60.52.3-1.91.92.0-1.7-1.81.8
Short access day 1 total infusions0.10.10.30.30.20.2-0.10.1-0.2-0.60.50.5-0.6-0.40.10.3-0.4
Short access day 10 total infusions1.92.14.0-0.3-0.51.6-1.51.4-1.7-1.70.01.6-1.6-2.01.51.6-1.6
Short access total infusions1.31.42.60.2-0.11.3-1.21.3-1.5-1.60.51.3-1.3-1.51.21.2-1.3
Short access day 1 locomotion0.30.31.4-0.7-0.50.5-0.40.4-0.5-0.6-0.50.5-0.5-1.20.40.5-0.5
Short access day 10 total locomotion0.80.92.4-1.2-0.5-0.80.9-1.51.51.1-0.5-0.80.70.5-0.9-0.80.8
Short access total locomotion0.10.10.2-0.30.2-0.20.3-0.40.2-0.30.2-0.20.1-0.5-0.3-0.20.2
Compulsive drug intake2.42.45.8-1.5-0.9-1.61.5-1.41.52.4-0.9-1.61.61.6-1.5-1.61.6
One hour access (0.3 mA shock)2.02.37.8-2.6-2.81.2-1.20.9-0.90.7-2.31.1-1.1-1.01.11.1-1.1
One hour access (shock baseline)1.11.32.0-1.1-1.31.3-1.20.9-1.0-0.6-1.01.2-1.2-1.41.21.2-1.3
Number of responses in last shaping day4.04.16.0-2.0-2.52.1-2.11.8-2.0-0.8-2.21.9-2.0-2.32.12.1-2.1
Context. condit. distance diff. score1.62.06.31.72.2-1.21.2-0.90.8-0.72.5-1.41.40.2-1.4-1.31.3
Locomotion velocity, session 11.11.23.71.30.60.8-0.81.8-1.9-1.40.80.9-0.8-1.00.70.8-0.8
Locomotion distance, session 12.22.95.2-1.4-2.31.5-1.42.1-2.00.2-2.11.8-1.7-1.41.61.5-1.5
Locomotion velocity, session 22.83.34.70.4-0.42.2-2.12.2-2.0-1.9-0.12.1-2.1-1.62.12.1-2.1
Locomotion distance, session 21.82.65.9-1.8-2.41.4-1.31.7-1.70.2-2.21.6-1.5-1.31.51.4-1.4
Locomotion velocity, session 30.30.31.20.90.9-0.40.4-0.00.1-0.61.1-0.40.4-0.3-0.4-0.40.4
Locomotion distance, session 30.40.51.8-1.1-1.1-0.40.3-0.30.41.3-0.9-0.40.40.5-0.5-0.40.4
Stereotopy head waving bouts, day 30.40.51.51.21.20.2-0.30.3-0.3-1.21.20.2-0.2-0.20.20.2-0.2
Stereotopy head waving duration, day 31.72.07.22.72.50.5-0.60.7-0.7-2.32.50.5-0.5-0.30.60.6-0.6
Locomotion velocity, session 70.30.41.71.21.1-0.30.30.10.1-0.11.30.1-0.00.9-0.0-0.20.1
Locomotion distance, session 70.91.11.60.80.9-1.31.2-0.40.20.71.2-1.11.21.1-1.2-1.21.2
Stereotopy head waving bouts, day 72.22.57.62.72.21.1-1.11.4-1.3-2.62.01.1-1.1-0.81.11.1-1.1
Stereotopy head waving duration, day 71.51.85.12.11.61.1-1.21.1-0.9-2.31.21.0-1.0-1.01.11.1-1.1
Locomotion velocity, session 81.31.64.21.91.50.7-0.71.3-1.6-2.12.00.7-0.6-1.10.60.6-0.6
Locomotion distance, session 80.10.20.40.70.5-0.10.20.5-0.6-0.60.6-0.00.0-0.6-0.1-0.10.1
Degree of sensitization distance1.91.96.02.32.5-1.11.2-0.30.0-0.92.4-1.11.10.6-1.1-1.11.1
Degree of sensitization stereotypy2.32.55.82.21.41.4-1.51.7-1.6-2.41.21.4-1.4-1.31.41.5-1.5
Condit. Reinf. active minus inactive responses1.21.32.0-0.30.0-1.41.4-1.11.01.3-0.2-1.31.31.2-1.3-1.41.4
Condit. Reinf. active-inactive response ratio1.01.11.70.10.4-1.31.3-1.01.00.90.3-1.31.31.0-1.3-1.31.3
Condit. Reinf. active responses3.44.16.0-1.0-0.2-2.42.4-2.12.02.4-0.7-2.32.31.7-2.3-2.42.4
Condit. Reinf. inactive responses4.04.76.8-1.4-0.5-2.52.6-2.42.32.6-0.9-2.42.41.5-2.4-2.52.5
Incentive salience index mean1.72.04.3-0.40.2-1.61.6-1.51.41.8-0.2-1.41.52.1-1.5-1.51.5
Condit. Reinf. lever presses1.52.06.2-0.60.1-1.51.3-1.61.61.9-0.4-1.31.32.5-1.3-1.31.3
Time in familiar zone, hab. session 10.70.61.10.70.30.8-0.91.0-0.9-0.50.21.0-1.00.20.90.9-0.9
Time in novel zone, hab. session 10.10.10.50.30.60.1-0.0-0.30.3-0.70.5-0.10.1-0.5-0.00.0-0.0
Total zone transitions, hab. session 10.70.93.7-1.9-1.9-0.20.20.3-0.21.4-1.90.2-0.1-0.3-0.0-0.10.1
Total locomotion distance, hab. session 10.30.41.5-1.2-1.0-0.50.5-0.20.31.1-0.9-0.20.30.2-0.3-0.40.4
Locomotion velocity, hab. session 10.40.61.9-1.4-1.2-0.50.6-0.30.41.2-1.1-0.30.40.3-0.4-0.50.5
Time in familiar zone, hab. session 20.10.10.7-0.2-0.20.0-0.2-0.50.80.5-0.30.1-0.10.50.10.1-0.1
Time in novel zone, hab. session 20.20.20.4-0.5-0.2-0.30.40.1-0.5-0.10.1-0.40.4-0.6-0.4-0.40.4
Total zone transitions, hab. session 20.10.20.7-0.7-0.8-0.10.10.3-0.40.7-0.70.3-0.20.30.20.0-0.1
Total locomotion distance, hab. session 20.30.40.9-0.4-0.70.4-0.40.8-0.9-0.1-0.80.7-0.7-0.40.70.5-0.5
Locomotion velocity, hab. session 20.20.30.7-0.3-0.70.3-0.20.7-0.80.2-0.80.6-0.60.00.50.4-0.4
Novel to familiar place preference ratio0.30.31.00.81.0-0.20.30.2-0.4-0.90.9-0.20.3-0.6-0.3-0.30.3
Novelty place preference0.30.31.20.81.1-0.30.40.0-0.2-0.91.1-0.30.3-0.5-0.3-0.30.3
Time in novel zone, NPP test0.40.41.40.81.2-0.40.5-0.1-0.2-0.81.2-0.50.5-0.5-0.5-0.50.5
Total zone transitions, NPP test0.50.73.1-1.4-1.7-0.10.10.5-0.51.3-1.80.3-0.1-0.10.1-0.0-0.0
Total locomotion distance, NPP test0.20.21.1-0.2-0.60.00.10.9-1.00.3-0.70.3-0.2-0.20.10.0-0.0
Locomotion velocity, NPP test0.30.41.4-0.5-1.00.2-0.10.9-1.00.6-1.20.5-0.4-0.10.30.2-0.2
Pavlov. Cond. lever latency0.10.10.60.10.20.10.00.0-0.0-0.50.50.1-0.1-0.80.10.0-0.0
Pavlov. Cond. magazine entry latency1.21.62.5-0.9-1.41.4-1.51.2-1.2-0.1-1.61.3-1.3-0.31.31.5-1.4
Pavlov. Cond. change in total contacts0.90.92.5-1.0-1.50.9-0.90.8-0.80.4-1.61.0-0.9-0.20.90.9-0.9
Pavlov. Cond. index score0.20.30.5-0.2-0.40.6-0.70.6-0.50.0-0.50.6-0.60.40.60.7-0.7
Pavlov. Cond. latency score0.10.20.3-0.1-0.30.5-0.60.4-0.40.0-0.40.4-0.40.40.40.5-0.5
Pavlov. Cond. lever contacts0.10.10.8-0.1-0.3-0.10.00.1-0.00.6-0.60.0-0.00.90.00.0-0.0
Pavlov. Cond. magazine entry number0.60.81.40.81.1-0.90.9-0.90.9-0.21.2-0.90.90.0-0.9-0.90.9
Pavlov. Cond. intertrial magazine entries2.32.84.9-0.10.4-2.12.2-1.61.51.70.3-1.81.91.5-1.9-2.12.1
Pavlov. Cond. lever-magazine prob. diff.0.30.30.5-0.4-0.60.6-0.70.5-0.50.2-0.70.6-0.60.50.60.6-0.6
Pavlov. Cond. response bias0.40.40.9-0.5-0.80.6-0.70.6-0.60.4-0.90.6-0.60.50.60.7-0.7
Bone: apparent density0.00.00.1-0.1-0.1-0.20.1-0.20.30.2-0.3-0.20.20.1-0.2-0.20.2
Bone surface0.40.61.20.1-0.21.0-1.10.7-0.4-0.7-0.31.0-1.0-0.61.01.0-1.0
Bone volume0.00.10.2-0.2-0.20.2-0.2-0.20.50.0-0.30.2-0.20.00.20.2-0.2
Bone: connectivity density0.10.20.40.50.6-0.40.3-0.20.40.00.4-0.50.50.5-0.5-0.40.4
Bone: cortical apparent density0.81.02.8-0.6-0.1-1.01.0-1.11.11.5-0.2-0.90.91.7-1.0-1.01.0
Bone: cortical area0.50.81.60.60.41.1-1.20.8-0.6-1.00.31.1-1.10.11.11.2-1.2
Bone: cortical porosity1.51.63.60.90.71.4-1.41.3-1.4-1.90.71.1-1.2-1.21.21.3-1.3
Bone: cortical porosity2.62.86.11.10.71.8-1.91.7-1.9-2.50.81.6-1.6-1.61.71.8-1.8
Bone: cortical thickness0.40.62.6-1.6-1.40.5-0.70.00.10.7-1.30.4-0.40.20.40.5-0.5
Bone: cortical thickness0.60.72.5-1.6-1.60.6-0.80.2-0.30.7-1.50.6-0.5-0.00.50.6-0.6
Bone: cortical tissue density0.81.12.8-0.50.0-1.11.0-1.11.21.5-0.1-0.91.01.7-1.0-1.01.0
Bone: elastic displacement0.30.41.71.31.10.1-0.30.5-0.5-0.91.00.1-0.20.00.20.2-0.2
Bone: elastic work1.72.35.82.41.71.3-1.31.5-1.4-2.41.31.2-1.2-0.81.21.3-1.3
Bone: endosteal estimation1.22.56.42.41.91.2-1.21.4-1.4-2.52.01.2-1.3-0.81.31.2-1.2
Bone: endosteal perimeter1.83.88.02.51.91.8-1.91.5-1.2-2.82.12.0-2.0-0.62.01.9-1.9
Bone: final force1.11.92.71.10.61.6-1.61.5-1.4-1.60.61.5-1.5-0.51.51.6-1.6
Bone: final moment1.01.72.91.40.81.5-1.51.4-1.3-1.70.81.3-1.4-0.41.41.5-1.4
Bone: marrow area1.32.77.02.52.01.3-1.21.4-1.4-2.62.11.3-1.3-0.91.31.3-1.3
Bone: maximum diameter1.83.27.72.32.01.6-1.71.4-1.3-2.82.01.7-1.7-0.51.71.7-1.7
Bone: maximum force1.42.43.81.30.81.7-1.81.8-1.7-1.90.91.6-1.6-0.71.61.7-1.7
Bone: maximum moment1.42.44.31.51.01.6-1.71.7-1.7-2.11.01.6-1.6-0.71.61.7-1.6
Bone: minimum diameter0.30.51.40.70.50.7-0.70.7-0.8-1.20.80.7-0.7-0.70.70.7-0.7
Bone: periosteal estimation1.32.65.71.91.41.6-1.71.4-1.3-2.41.51.6-1.6-0.71.61.6-1.6
Bone: periosteal perimeter2.03.47.22.52.11.7-1.81.2-1.0-2.72.21.8-1.8-0.11.81.8-1.8
Bone: post-yield work1.11.52.40.3-0.21.4-1.51.4-1.4-0.9-0.21.6-1.5-0.41.51.5-1.5
Bone: stiffness0.71.11.91.41.10.9-1.01.1-1.0-1.41.00.9-1.00.21.01.0-1.0
Bone: tissue strength0.10.10.20.50.50.1-0.10.3-0.4-0.50.40.1-0.1-0.10.10.1-0.1
Bone: trabecular number0.00.10.10.30.4-0.20.1-0.10.20.00.4-0.20.20.4-0.2-0.10.1
Bone: trabecular spacing0.60.81.10.80.60.8-1.00.7-0.8-0.80.91.1-1.00.51.01.0-1.0
Bone: trabecular thickness1.01.21.7-0.4-0.0-1.21.3-1.31.31.0-0.1-1.31.30.5-1.3-1.31.3
Bone: trabecular tissue density0.81.11.9-0.10.4-1.21.1-1.11.21.1-0.4-1.31.21.4-1.2-1.11.2
Breakpoint value in progressive ratio session0.30.31.4-1.2-0.9-0.00.1-0.50.40.7-0.9-0.10.0-0.00.1-0.10.0
Distance traveled before self-admin1.41.53.0-1.2-1.71.2-1.11.2-1.2-0.3-1.71.0-1.1-1.51.21.1-1.1
Distance traveled after self-admin0.20.20.70.80.80.2-0.20.0-0.1-0.60.80.1-0.10.3-0.00.2-0.2
Delta time in closed arm before/after self-admin0.10.10.4-0.7-0.50.2-0.20.2-0.2-0.0-0.30.2-0.1-0.60.10.1-0.1
Delta time in open arm before/after self-admin0.10.10.2-0.2-0.3-0.00.10.2-0.20.1-0.4-0.20.2-0.40.2-0.10.1
Diff in mean of infusions in LGA sessions0.30.30.8-0.5-0.3-0.70.6-0.60.60.9-0.1-0.50.50.5-0.5-0.60.6
Extinction: sum of active levers before priming2.12.13.8-1.2-2.01.4-1.41.4-1.50.1-1.61.5-1.5-1.21.71.5-1.5
Active lever presses in extinction session 60.10.10.30.30.00.3-0.30.5-0.6-0.20.00.4-0.4-0.10.50.3-0.4
Delta distance traveled before/after self-admin2.22.48.12.12.6-1.21.1-1.11.1-0.42.8-1.11.11.7-1.2-1.11.1
Delta ambulatory time before/after self-admin1.92.18.32.52.7-0.80.7-0.70.7-0.72.9-0.70.81.5-0.8-0.80.8
Time in closed arm before self-admin0.30.31.9-0.7-0.7-0.10.1-0.50.50.7-1.4-0.20.20.3-0.2-0.10.1
Time in closed arm after self-admin0.50.61.10.20.7-0.70.7-1.00.90.20.5-0.90.80.7-0.9-0.70.8
Time in open arm before self-admin0.60.61.00.70.8-0.90.9-0.70.80.41.0-0.70.80.9-0.7-0.80.8
Time in open arm after self-admin0.30.40.9-0.4-0.3-0.60.6-0.60.81.0-0.5-0.60.60.5-0.4-0.60.6
Sum of active levers in priming session hrs 5-60.10.10.1-0.2-0.30.2-0.20.3-0.4-0.0-0.30.2-0.2-0.40.30.2-0.2
Time to tail flick, vehicle, before self-admin0.10.10.3-0.4-0.0-0.20.2-0.1-0.0-0.10.5-0.10.1-0.5-0.0-0.20.2
Time to tail flick, vehicle, after self-admin0.60.71.10.30.7-1.01.0-1.00.90.60.5-0.90.90.9-0.8-0.90.9
Time to tail flick, test, before self-admin0.60.62.1-1.5-1.40.4-0.40.6-0.60.4-1.30.4-0.4-0.80.40.4-0.4
Time to tail flick, test, after self-admin0.30.31.0-0.4-0.3-0.40.3-0.40.41.0-0.8-0.30.30.9-0.7-0.30.3
Delta time to tail flick, vehicle, before/after SA0.10.10.20.40.2-0.20.2-0.00.00.2-0.4-0.30.20.2-0.1-0.20.2
Delta time to tail flick, test, before/after SA1.00.92.0-0.20.0-0.90.8-1.21.21.3-0.5-0.90.81.4-1.0-0.80.8
Ambulatory time before self-admin0.70.83.1-1.7-1.80.3-0.30.2-0.20.7-1.70.2-0.2-0.70.40.3-0.3
Ambulatory time after self-admin0.10.10.50.50.5-0.10.0-0.20.2-0.10.5-0.10.10.7-0.1-0.00.1
Total heroin consumption0.91.12.1-1.1-1.41.0-1.01.0-0.9-0.1-1.21.1-1.1-1.21.21.0-1.0
Area under the delay curve1.31.45.0-1.6-2.20.8-0.61.0-1.00.7-2.00.7-0.7-1.20.60.7-0.7
Delay disc. indifference point, 0s delay0.10.10.4-0.4-0.30.4-0.3-0.00.0-0.3-0.30.2-0.3-0.70.30.4-0.4
Delay disc. indifference point, 16s delay1.81.84.9-1.6-2.21.2-1.21.4-1.40.4-2.01.1-1.1-1.01.01.1-1.1
Delay disc. indifference point, 2s delay5.56.211.7-2.6-3.42.5-2.32.4-2.5-0.3-2.82.4-2.4-3.02.22.4-2.4
Delay disc. indifference point, 24s delay0.30.30.80.60.20.4-0.50.7-0.60.10.20.6-0.50.90.30.5-0.5
Delay disc. indifference point, 4s delay1.11.22.3-0.9-1.51.1-0.91.4-1.4-0.2-1.30.9-0.9-1.50.70.9-0.9
Delay disc. indifference point, 8s delay0.80.93.0-1.4-1.6-0.60.7-0.40.41.7-1.5-0.50.50.1-0.5-0.60.6
Delay discount exponential model param1.31.45.21.72.3-0.80.6-1.01.0-0.72.0-0.70.71.2-0.6-0.70.7
Delay discount hyperbolic model param1.71.86.11.82.5-1.10.8-1.31.2-0.62.1-1.00.91.5-0.8-1.01.0
Fecal boli incidents, locomotor time 10.10.10.90.50.5-0.1-0.1-0.00.00.10.3-0.10.10.9-0.2-0.00.0
Change in fecal boli incidents, locomotor task0.10.10.40.30.40.1-0.1-0.10.1-0.10.60.2-0.10.30.10.1-0.1
Time >=10cm from walls, locomotor time 10.40.41.30.70.90.5-0.50.5-0.5-1.10.90.5-0.5-0.10.60.5-0.5
Bouts of movement, locomotor time 10.00.00.20.20.4-0.0-0.0-0.10.1-0.10.40.0-0.00.3-0.10.0-0.0
Total resting periods, locomotor time 10.10.10.20.40.50.1-0.20.0-0.1-0.20.40.1-0.10.40.00.2-0.2
Rest time, locomotor task time 10.40.41.20.71.0-0.50.4-0.60.40.11.1-0.60.61.0-0.7-0.50.5
Distance moved, locomotor task time 10.10.10.30.30.40.1-0.10.3-0.1-0.60.30.2-0.2-0.40.40.2-0.2
Vertical activity count, locomotor time 12.32.44.10.51.2-1.91.7-1.92.01.11.0-1.61.61.7-1.5-1.71.7
Time >=10cm from walls, locomotor time 20.80.93.61.91.8-0.2-0.1-0.10.2-0.31.3-0.0-0.01.80.00.1-0.1
Bouts of movement, locomotor time 21.51.63.8-2.0-1.91.3-1.30.5-0.6-0.0-1.51.2-1.3-1.41.01.3-1.3
Total resting periods, locomotor time 22.12.24.5-2.1-2.11.5-1.50.9-1.0-0.1-1.71.4-1.5-1.71.21.5-1.5
Rest time, locomotor task time 20.00.00.1-0.3-0.30.1-0.20.1-0.30.2-0.10.00.00.2-0.20.0-0.0
Distance moved, locomotor task time 20.40.41.81.41.3-0.50.6-0.20.4-0.20.9-0.30.30.50.0-0.40.4
Vertical activity count, locomotor time 21.51.73.21.21.7-1.31.2-1.51.70.61.5-1.11.11.8-0.8-1.11.1
Weight adjusted by age0.40.52.21.51.20.2-0.20.4-0.3-0.81.10.5-0.50.40.40.3-0.4
Seeking ratio, delayed vs. immediate footshock0.30.40.9-0.2-0.60.5-0.60.9-0.9-0.2-0.80.5-0.5-0.90.40.5-0.5
Locomotion in novel chamber1.51.94.4-1.6-1.0-1.41.4-1.41.42.1-1.5-1.21.20.8-1.3-1.31.3
Locomotion in novel chamber post-restriction1.21.45.0-2.1-2.20.8-0.70.3-0.40.8-2.00.9-0.9-0.70.70.8-0.8
Progressive ratio0.10.10.70.0-0.0-0.40.50.1-0.2-0.10.1-0.40.4-0.9-0.2-0.50.4
Food seeking constrained by brief footshock0.70.91.7-0.2-0.51.1-1.11.0-0.9-0.7-0.51.2-1.2-0.71.31.1-1.1
Seeking ratio, punishment vs. effort0.40.50.9-0.0-0.30.9-1.00.6-0.5-0.2-0.40.9-0.90.40.90.9-0.9
Run reversals in cocaine runway, females0.30.31.40.30.6-0.50.4-0.70.70.50.2-0.50.51.2-0.5-0.40.5
Run reversals in cocaine runway, males0.20.20.50.20.2-0.40.60.5-0.5-0.20.5-0.40.4-0.7-0.1-0.60.5
Latency to leave start box in cocaine runway1.92.14.01.00.31.7-1.71.7-1.7-2.00.41.4-1.5-1.51.31.6-1.6
Latency to leave start box in cocaine runway, F3.03.35.10.5-0.32.2-2.32.1-2.0-1.8-0.52.0-2.0-1.41.92.2-2.2
Latency to leave start box in cocaine runway, M0.40.41.60.50.50.5-0.40.4-0.7-1.30.90.3-0.3-1.30.20.4-0.3
Cd content in liver0.70.81.5-0.6-0.71.2-1.00.8-0.9-0.8-0.70.8-0.8-1.20.81.1-1.0
Co content in liver0.30.40.7-0.4-0.40.8-0.80.1-0.1-0.3-0.80.7-0.7-0.20.60.9-0.8
Cu content in liver1.01.26.2-1.9-2.00.2-0.10.00.11.5-2.50.3-0.30.00.40.2-0.3
Fe content in liver1.01.25.02.22.20.0-0.10.2-0.5-1.71.90.3-0.3-0.00.40.1-0.2
K content in liver0.40.40.90.1-0.50.7-0.60.6-0.6-0.4-0.40.9-0.9-0.80.90.7-0.7
Mg content in liver0.20.20.50.2-0.20.4-0.30.3-0.2-0.3-0.20.6-0.6-0.50.70.4-0.5
Mn content in liver0.40.41.8-1.3-1.30.4-0.30.2-0.20.3-0.80.5-0.4-0.70.10.4-0.4
Na content in liver0.20.20.5-0.0-0.2-0.40.5-0.50.70.5-0.5-0.30.30.40.0-0.40.4
Rb content in liver0.10.10.40.10.2-0.40.4-0.20.20.40.1-0.10.10.6-0.2-0.30.3
Se content in liver0.50.62.9-1.3-1.30.5-0.40.2-0.20.6-1.70.5-0.5-0.50.60.4-0.5
Sr content in liver1.81.75.8-2.4-2.2-0.60.6-0.60.62.0-2.4-0.60.60.0-0.6-0.70.7
Zn content in liver0.60.61.4-0.6-0.91.0-0.90.5-0.2-0.1-1.20.8-0.8-0.50.81.0-0.9