Hub : Genes

Nab1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000012959 0.28 0.1 0.0e+00 0.24 0.25 0.25 0.25 4.7e-26 1.8e-27 1.4e-27 4.9e-27
2 Adipose mRNA stability ENSRNOG00000012959 0.1 0.05 1.0e-13 0.08 0.07 0.07 0.07 4.3e-09 1.3e-08 2.6e-08 1.5e-08
3 BLA gene expression ENSRNOG00000012959 0.14 0.1 6.9e-06 0.04 0.07 0.02 0.07 4.9e-03 1.6e-04 1.8e-02 1.3e-04
4 Brain gene expression ENSRNOG00000012959 0.2 0.11 0.0e+00 0.22 0.24 0.23 0.23 1.8e-20 2.3e-22 3.7e-21 1.2e-21
5 Eye gene expression ENSRNOG00000012959 0.33 0.21 4.4e-03 0.1 0.16 0.1 0.14 1.5e-02 1.8e-03 1.1e-02 4.1e-03
6 LHb gene expression ENSRNOG00000012959 0.35 0.17 1.3e-05 0.13 0.11 0.1 0.08 6.1e-04 1.6e-03 3.0e-03 6.1e-03
7 NAcc gene expression ENSRNOG00000012959 0.14 0.1 4.2e-09 0.1 0.11 0.1 0.11 1.0e-07 1.3e-08 4.1e-08 2.0e-08
8 OFC gene expression ENSRNOG00000012959 0.36 0.16 7.8e-08 0.28 0.24 0.26 0.25 1.7e-07 2.6e-06 8.6e-07 1.3e-06
9 PL gene expression ENSRNOG00000012959 0.09 0.06 1.5e-06 0.08 0.09 0.09 0.08 1.5e-06 4.4e-07 1.8e-07 7.1e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail6.420.622.44.44.64.54.64.44.74.44.74.5
BMI without tail1.63.33.82.01.91.51.91.91.91.81.91.6
Body weight0.00.10.40.00.30.70.3-0.10.2-0.10.20.2
Epididymis fat weight0.41.01.5-1.1-0.9-0.4-0.9-1.2-0.9-1.2-0.9-1.0
Glucose0.71.11.71.31.00.51.01.21.01.21.10.7
Heart weight0.50.70.7-0.8-0.8-0.7-0.8-0.8-0.9-0.8-0.8-0.8
Left kidney weight0.00.10.3-0.5-0.20.3-0.2-0.5-0.3-0.6-0.3-0.2
Right kidney weight0.10.31.6-0.10.51.30.5-0.10.4-0.10.40.5
Tail length4.714.215.5-3.7-3.7-3.4-3.7-3.8-3.9-3.9-3.8-3.9
Length with tail4.817.720.1-4.4-4.1-3.4-4.1-4.5-4.3-4.5-4.4-4.1
Length without tail0.40.91.8-1.3-0.80.2-0.7-1.3-0.9-1.3-0.9-0.5
Liver weight, left0.10.20.5-0.7-0.30.7-0.2-0.6-0.3-0.5-0.30.1
Liver weight, right0.10.10.3-0.5-0.20.3-0.2-0.5-0.2-0.5-0.2-0.2
Parametrial fat weight0.00.00.10.20.20.20.20.10.20.00.2-0.1
Retroperitoneal fat weight0.00.10.40.00.40.70.4-0.10.4-0.10.40.2
Intraocular pressure0.30.40.60.80.50.50.60.70.60.70.60.5
Extensor digitorum longus weight3.815.432.32.84.05.74.22.94.02.94.04.1
Soleus weight0.20.62.70.10.61.60.80.30.60.30.71.0
Tibialis anterior weight2.79.414.22.63.13.83.22.63.12.73.13.3
Tibia length4.913.716.5-4.1-3.8-2.7-3.7-4.0-3.7-3.9-3.8-3.6
Number of licking bursts0.30.40.80.90.5-0.50.40.80.50.80.50.4
Food consumed during 24 hour testing period0.60.71.1-1.1-0.8-0.4-0.8-1.0-0.8-0.9-0.8-0.5
Times rat made contact with spout0.10.20.40.60.2-0.60.10.60.20.50.20.0
Mean time between licks in bursts1.21.73.30.91.31.81.41.01.31.11.31.5
Mean num. licks in bursts0.00.00.1-0.3-0.10.3-0.1-0.2-0.1-0.2-0.1-0.1
Std. dev. time between licks in bursts6.47.68.52.62.82.72.82.62.82.72.82.9
Water consumed over 24 hours0.91.01.21.11.10.71.01.11.01.11.00.9
Indifference point 0 sec4.57.28.22.42.72.62.62.72.72.82.72.9
Indifference point AUC0.30.41.00.30.50.80.50.50.50.60.61.0
Indifference point function ln k0.91.32.21.51.10.41.11.41.21.31.20.9
Indifference point function log k0.91.32.21.51.10.41.11.41.21.31.20.9
Delay discounting total patch changes 0 sec4.47.28.52.42.72.62.62.72.72.82.72.9
Delay discounting total patch changes 12 sec0.70.91.30.70.91.00.90.90.91.00.91.1
Delay discounting total patch changes 18 sec2.22.93.91.51.71.51.71.71.71.91.72.0
Delay discounting total patch changes 24 sec1.31.72.21.11.21.11.21.31.31.41.31.5
Delay discounting total patch changes 6 sec3.95.97.72.22.52.22.42.42.42.52.42.8
Delay discounting time to switch 0 sec1.11.72.2-1.2-1.3-1.3-1.3-1.2-1.3-1.3-1.3-1.5
Delay discounting water rate 0 sec0.91.52.01.11.21.41.21.11.21.11.21.2
Delay discounting water rate 12 sec0.40.61.01.00.70.40.80.90.80.90.70.6
Delay discounting water rate 18 sec0.10.10.30.50.3-0.30.20.40.20.30.3-0.1
Delay discounting water rate 24 sec0.00.10.2-0.1-0.10.2-0.1-0.3-0.1-0.3-0.1-0.5
Delay discounting water rate 6 sec1.32.02.71.71.40.81.41.61.41.61.41.2
Locomotor activity0.00.10.10.20.30.20.20.20.30.20.30.2
Locomotor testing distance0.00.00.30.20.0-0.5-0.10.30.00.30.00.0
Locomotor testing rearing0.50.81.21.10.90.20.81.10.91.10.90.7
Light reinforcement 14.07.410.42.32.83.22.82.32.82.42.82.9
Light reinforcement 20.71.01.40.80.91.11.00.91.00.91.01.2
Reaction time number correct1.52.12.51.41.61.61.51.31.51.31.61.4
Reaction time mean minus median3.24.14.8-1.9-2.1-2.1-2.2-1.8-2.1-1.9-2.2-1.9
Reaction time mean minus median AUC2.33.03.5-1.6-1.8-1.9-1.8-1.5-1.8-1.6-1.9-1.7
Reaction time num false alarms3.24.46.51.82.22.62.31.72.21.72.22.1
Reaction time num false alarms AUC3.34.67.11.82.22.72.31.72.21.72.32.2
Reaction time trials correct on left1.52.12.51.41.61.61.51.31.51.31.61.4
Reaction time trials on left1.42.02.41.31.51.51.51.31.41.21.51.4
Reaction time mean9.012.314.2-3.2-3.6-3.5-3.6-3.3-3.6-3.4-3.6-3.8
Reaction time mean AUC7.910.512.2-2.9-3.3-3.3-3.3-3.0-3.3-3.1-3.3-3.5
Median of all reaction times8.511.514.2-3.1-3.4-3.4-3.4-3.2-3.4-3.3-3.4-3.8
Reaction time omissions0.40.50.8-0.5-0.6-0.9-0.7-0.5-0.7-0.6-0.6-0.9
Reaction time false alarm rate1.21.62.71.01.31.71.41.01.41.01.41.3
Reaction time premature initiation rate0.00.00.0-0.00.0-0.00.00.10.00.00.0-0.1
Reaction time premature initiations0.40.50.70.70.80.70.80.70.80.70.80.6
Std. dev. reaction times7.810.711.8-3.1-3.4-3.3-3.4-3.0-3.4-3.1-3.4-3.3
Reaction time trials completed1.42.02.41.31.51.51.51.31.41.21.51.4
Reaction time trials AUC1.41.92.21.31.51.51.51.31.41.21.51.3
Social response proportion1.11.21.7-1.0-1.2-0.7-1.1-1.1-1.1-1.1-1.2-1.3
Social responses0.00.00.2-0.2-0.10.4-0.1-0.2-0.1-0.3-0.2-0.2
Social time0.60.81.2-0.6-0.9-1.1-0.9-0.6-0.9-0.7-1.0-1.0
Conditioned locomotion0.00.00.1-0.1-0.1-0.2-0.1-0.2-0.1-0.3-0.1-0.3
Cocaine response after cond. corrected0.10.10.5-0.5-0.10.7-0.0-0.5-0.1-0.5-0.1-0.2
Cocaine response after cond. not corrected1.21.42.3-1.5-1.10.0-0.9-1.5-1.0-1.5-1.0-1.1
Cocaine response before conditioning1.11.31.6-1.3-1.2-0.8-1.2-1.2-1.2-1.2-1.2-1.2
Saline control response0.20.20.40.60.3-0.20.30.60.40.60.40.4
Condit. Reinf. active minus inactive responses4.35.35.6-2.3-2.4-2.0-2.3-2.3-2.4-2.4-2.4-2.3
Condit. Reinf. active-inactive response ratio3.43.53.9-1.8-2.0-2.0-1.9-1.8-2.0-1.8-2.0-1.8
Condit. Reinf. active responses1.21.72.0-1.4-1.3-0.8-1.3-1.4-1.3-1.4-1.3-1.3
Condit. Reinf. inactive responses0.00.00.2-0.20.00.50.1-0.20.0-0.20.0-0.0
Condit. Reinf. lever presses0.10.10.2-0.4-0.4-0.1-0.4-0.4-0.4-0.3-0.4-0.2
Condit. Reinf. lever reinforcers received1.11.62.0-1.4-1.2-0.7-1.2-1.4-1.2-1.4-1.2-1.2
Pavlov. Cond. lever latency0.30.40.50.70.70.60.70.60.70.60.70.5
Pavlov. Cond. magazine entry latency0.40.40.5-0.7-0.7-0.5-0.7-0.7-0.7-0.6-0.7-0.5
Pavlov. Cond. change in total contacts1.11.51.7-1.3-1.3-1.2-1.3-1.1-1.3-1.1-1.3-1.0
Pavlov. Cond. index score0.81.01.3-1.1-1.1-0.8-1.1-1.0-1.1-1.0-1.1-0.8
Pavlov. Cond. latency score0.81.01.4-1.2-1.1-0.8-1.0-1.0-1.1-1.0-1.1-0.7
Pavlov. Cond. lever contacts0.60.81.0-1.0-1.0-0.9-1.0-0.8-1.0-0.8-1.0-0.7
Pavlov. Cond. magazine entry number0.81.01.21.11.11.01.10.91.10.91.10.8
Pavlov. Cond. intertrial magazine entries1.01.21.41.21.21.01.21.11.21.11.21.0
Pavlov. Cond. lever-magazine prob. diff.0.40.60.8-0.9-0.9-0.5-0.8-0.8-0.8-0.7-0.8-0.5
Pavlov. Cond. response bias1.21.62.0-1.4-1.4-1.1-1.3-1.3-1.3-1.2-1.3-1.0
Conditioned reinforcement - actives0.60.60.7-0.8-0.8-0.7-0.8-0.8-0.8-0.8-0.8-0.8
Conditioned reinforcement - inactives1.21.41.5-1.2-1.2-1.1-1.2-1.2-1.2-1.2-1.2-1.1
Conditioned locomotion1.51.83.20.91.41.81.41.01.21.11.21.7
Intermittent access intake day 1-15 change1.11.11.21.11.00.71.01.01.11.11.11.1
Intermittent access intake escalation0.40.40.50.70.60.30.60.60.70.60.70.6
Intermittent access intake escalation 20.10.10.20.40.3-0.10.30.40.30.30.30.2
Intermitt. access day 1 inactive lever presses0.10.10.10.20.20.30.30.30.30.30.30.3
Intermitt. access day 15 inactive lever presses1.01.11.4-0.9-1.1-1.2-1.1-1.0-1.1-1.0-1.1-1.2
Intermitt. access escalation Index0.90.81.01.00.90.71.00.91.00.81.00.6
Intermittent access day 1 total infusions0.40.51.2-0.4-0.6-1.1-0.7-0.4-0.8-0.4-0.8-0.6
Intermittent access day 15 total infusions0.20.20.40.60.4-0.20.30.60.30.50.30.4
Intermittent access terminal intake (last 3 days)0.50.50.90.90.70.10.60.90.60.90.60.7
Intermittent access total infusions0.10.10.60.1-0.1-0.7-0.20.1-0.30.1-0.3-0.1
Intermittent access day 1 locomotion0.00.00.1-0.1-0.1-0.3-0.2-0.1-0.3-0.1-0.30.1
Intermittent access day 15 total locomotion0.00.00.1-0.2-0.2-0.1-0.2-0.2-0.4-0.2-0.40.1
Intermittent access total locomotion0.10.10.30.40.30.10.30.40.20.40.20.6
Intermittent access standard deviation0.20.20.40.50.40.50.50.50.50.50.50.6
Cocaine induced anxiety3.54.16.71.72.12.62.21.62.11.62.12.1
Post-drug Anxiety1.61.82.91.21.41.71.51.11.41.01.41.2
Baseline Anxiety2.62.74.6-1.3-1.7-2.1-1.7-1.3-1.7-1.4-1.7-1.8
Lifetime Intake0.00.00.10.20.2-0.30.10.2-0.10.3-0.10.2
Incentive Sensitization - Responses0.40.40.5-0.5-0.6-0.7-0.6-0.6-0.7-0.6-0.7-0.7
Incentive Sensitization - Breakpoint0.30.30.4-0.4-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.6
Progressive ratio test 1 active lever presses0.10.10.10.10.20.40.20.20.20.20.20.3
Progressive ratio test 1 breakpoint0.10.10.20.20.30.40.30.20.20.20.20.5
Progressive ratio test 1 inactive lever presses0.00.00.1-0.20.00.30.0-0.1-0.1-0.1-0.10.2
Progressive ratio test 2 active lever presses0.10.10.2-0.3-0.3-0.5-0.3-0.3-0.4-0.3-0.4-0.4
Progressive ratio test 2 breakpoint0.00.00.10.20.1-0.30.00.1-0.10.1-0.10.0
Progressive ratio test 2 inactive lever presses0.20.20.3-0.5-0.5-0.4-0.5-0.4-0.5-0.5-0.5-0.4
Total sessions with >9 infusions0.50.61.80.30.81.30.80.30.60.40.61.0
Short access day 1 total inactive lever presses0.00.00.2-0.2-0.10.40.0-0.1-0.0-0.1-0.00.3
Short access day 10 total inactive lever presses0.70.81.0-1.0-1.0-0.6-0.9-1.0-0.9-1.0-0.9-0.9
Short access day 1 total infusions0.10.10.30.00.20.30.10.10.10.20.10.6
Short access day 10 total infusions0.10.10.30.50.3-0.60.10.4-0.10.4-0.10.1
Short access total infusions0.20.20.50.50.60.20.50.50.30.50.30.7
Short access day 1 locomotion0.10.10.4-0.00.20.40.20.10.10.10.10.6
Short access day 10 total locomotion0.20.20.4-0.6-0.5-0.1-0.4-0.6-0.5-0.6-0.5-0.3
Short access total locomotion0.10.10.6-0.10.30.80.3-0.00.20.00.20.7
Compulsive drug intake0.10.10.30.40.30.30.40.30.50.30.5-0.0
One hour access (0.3 mA shock)0.10.20.7-0.0-0.3-0.8-0.3-0.2-0.3-0.2-0.3-0.6
One hour access (shock baseline)0.20.30.8-0.3-0.5-0.9-0.5-0.3-0.6-0.3-0.6-0.5
Number of responses in last shaping day0.30.30.50.40.50.60.50.40.40.50.40.7
Context. condit. distance diff. score1.41.72.91.71.30.41.31.61.31.51.30.9
Locomotion velocity, session 10.00.00.10.30.30.20.20.20.20.10.2-0.1
Locomotion distance, session 10.20.30.50.40.60.70.60.40.50.40.50.2
Locomotion velocity, session 21.51.82.91.11.41.71.41.11.41.11.41.4
Locomotion distance, session 20.50.71.90.50.91.40.90.60.90.60.90.8
Locomotion velocity, session 30.20.20.30.50.50.40.50.50.50.50.50.2
Locomotion distance, session 30.50.60.90.90.80.30.70.90.80.90.80.6
Stereotopy head waving bouts, day 30.50.60.70.70.80.80.80.70.80.70.80.7
Stereotopy head waving duration, day 30.00.00.10.20.20.10.20.10.20.10.20.1
Locomotion velocity, session 70.10.10.8-0.20.20.90.3-0.20.2-0.10.20.2
Locomotion distance, session 70.10.20.9-0.00.31.00.4-0.10.3-0.10.30.4
Stereotopy head waving bouts, day 70.20.20.4-0.3-0.4-0.6-0.4-0.3-0.4-0.4-0.4-0.5
Stereotopy head waving duration, day 70.70.81.1-0.8-0.9-1.0-0.9-0.8-0.9-0.8-0.9-1.0
Locomotion velocity, session 80.50.60.80.90.70.30.70.90.70.90.70.7
Locomotion distance, session 81.52.32.71.71.61.21.51.61.61.61.61.2
Degree of sensitization distance0.50.51.0-1.0-0.60.3-0.5-1.0-0.6-1.0-0.6-0.4
Degree of sensitization stereotypy0.20.20.6-0.2-0.4-0.8-0.5-0.2-0.5-0.2-0.5-0.4
Condit. Reinf. active minus inactive responses5.46.07.3-2.3-2.5-2.4-2.4-2.4-2.5-2.5-2.5-2.7
Condit. Reinf. active-inactive response ratio3.13.33.9-1.7-1.9-1.8-1.8-1.8-1.8-1.9-1.8-2.0
Condit. Reinf. active responses4.75.86.7-2.3-2.4-2.0-2.3-2.5-2.4-2.5-2.4-2.6
Condit. Reinf. inactive responses0.20.20.4-0.5-0.30.1-0.3-0.6-0.4-0.6-0.4-0.5
Incentive salience index mean3.84.65.4-1.9-2.2-2.3-2.1-2.0-2.2-2.0-2.2-2.3
Condit. Reinf. lever presses0.50.71.7-0.5-0.9-1.3-0.9-0.6-0.9-0.6-0.9-1.0
Time in familiar zone, hab. session 10.60.60.80.90.80.40.80.80.80.80.80.8
Time in novel zone, hab. session 13.93.84.7-1.7-2.0-2.2-2.1-1.7-2.0-1.8-2.0-2.0
Total zone transitions, hab. session 10.20.30.6-0.8-0.50.1-0.5-0.7-0.5-0.7-0.5-0.6
Total locomotion distance, hab. session 11.42.03.3-1.8-1.3-0.2-1.3-1.8-1.4-1.7-1.4-1.2
Locomotion velocity, hab. session 10.40.51.1-1.1-0.50.5-0.5-1.0-0.6-0.9-0.6-0.4
Time in familiar zone, hab. session 20.00.00.10.10.0-0.2-0.00.10.00.10.00.0
Time in novel zone, hab. session 20.00.00.00.20.1-0.10.10.10.10.10.1-0.1
Total zone transitions, hab. session 20.00.00.10.30.20.10.20.20.20.20.2-0.1
Total locomotion distance, hab. session 20.50.71.1-1.0-0.7-0.2-0.7-1.0-0.8-1.0-0.8-1.0
Locomotion velocity, hab. session 20.40.60.9-0.9-0.6-0.0-0.6-0.9-0.7-1.0-0.7-0.9
Novel to familiar place preference ratio1.51.62.1-1.1-1.3-1.5-1.3-1.1-1.3-1.1-1.3-1.3
Novelty place preference1.01.01.8-0.8-1.0-1.3-1.1-0.8-1.0-0.8-1.0-1.1
Time in novel zone, NPP test1.11.22.1-0.9-1.1-1.4-1.2-0.8-1.1-0.9-1.1-1.2
Total zone transitions, NPP test0.30.50.90.60.81.00.80.50.70.50.70.2
Total locomotion distance, NPP test0.20.30.4-0.7-0.4-0.0-0.4-0.6-0.5-0.6-0.5-0.6
Locomotion velocity, NPP test0.00.00.1-0.30.00.4-0.0-0.2-0.0-0.2-0.0-0.2
Pavlov. Cond. lever latency2.22.84.71.31.82.21.71.41.71.41.71.8
Pavlov. Cond. magazine entry latency2.83.64.2-1.7-1.9-2.0-1.9-1.8-1.9-1.8-1.9-2.0
Pavlov. Cond. change in total contacts1.92.02.8-1.1-1.4-1.7-1.4-1.3-1.4-1.3-1.4-1.5
Pavlov. Cond. index score2.02.54.8-1.2-1.6-2.2-1.7-1.2-1.6-1.3-1.6-1.7
Pavlov. Cond. latency score2.32.94.9-1.3-1.7-2.2-1.8-1.4-1.7-1.4-1.7-1.9
Pavlov. Cond. lever contacts0.80.92.6-0.5-1.0-1.6-1.0-0.5-0.9-0.6-0.9-1.1
Pavlov. Cond. magazine entry number4.25.37.52.02.32.72.42.02.32.12.32.4
Pavlov. Cond. intertrial magazine entries0.00.10.20.20.20.40.30.10.20.10.20.1
Pavlov. Cond. lever-magazine prob. diff.1.62.03.8-1.1-1.5-2.0-1.5-1.1-1.4-1.2-1.4-1.5
Pavlov. Cond. response bias1.72.14.2-1.0-1.5-2.0-1.5-1.1-1.5-1.1-1.5-1.5
Bone: apparent density2.23.65.8-1.6-2.0-2.4-2.0-1.5-2.0-1.5-2.0-1.9
Bone surface0.71.31.7-1.3-1.2-0.9-1.2-1.2-1.2-1.1-1.2-1.0
Bone volume2.13.64.1-1.9-2.0-2.0-2.0-1.8-2.0-1.7-2.0-1.8
Bone: connectivity density0.20.30.8-0.4-0.5-0.9-0.6-0.3-0.6-0.3-0.5-0.4
Bone: cortical apparent density7.19.210.82.83.13.33.22.73.12.73.13.1
Bone: cortical area0.10.10.3-0.4-0.00.5-0.0-0.4-0.0-0.4-0.0-0.0
Bone: cortical porosity1.61.72.3-1.2-1.4-1.5-1.4-1.1-1.4-1.0-1.4-1.4
Bone: cortical porosity2.32.52.9-1.5-1.7-1.6-1.7-1.4-1.6-1.4-1.7-1.7
Bone: cortical thickness1.52.52.81.51.71.71.71.41.61.51.71.6
Bone: cortical thickness0.00.00.0-0.2-0.10.0-0.1-0.2-0.1-0.2-0.1-0.0
Bone: cortical tissue density6.99.010.72.73.13.33.12.73.12.73.13.1
Bone: elastic displacement0.10.10.40.30.0-0.7-0.10.4-0.00.40.0-0.1
Bone: elastic work1.62.12.4-1.4-1.5-1.4-1.5-1.4-1.5-1.4-1.5-1.6
Bone: endosteal estimation4.59.811.8-3.4-3.2-2.2-3.1-3.3-3.1-3.3-3.2-3.1
Bone: endosteal perimeter2.04.15.0-2.2-2.0-1.3-2.0-2.2-2.0-2.2-2.0-2.0
Bone: final force1.01.62.6-1.6-1.2-0.3-1.1-1.6-1.2-1.5-1.2-1.1
Bone: final moment0.50.81.5-1.2-0.8-0.0-0.8-1.2-0.8-1.1-0.8-0.7
Bone: marrow area4.39.211.1-3.3-3.1-2.1-3.0-3.2-3.0-3.2-3.1-3.0
Bone: maximum diameter0.00.00.1-0.3-0.10.2-0.1-0.4-0.1-0.3-0.1-0.1
Bone: maximum force2.33.95.8-2.4-2.0-0.9-1.9-2.3-1.9-2.2-2.0-1.8
Bone: maximum moment1.42.53.8-2.0-1.5-0.6-1.5-1.9-1.5-1.8-1.5-1.4
Bone: minimum diameter0.71.22.2-1.5-1.1-0.2-1.0-1.4-1.1-1.3-1.1-0.8
Bone: periosteal estimation2.44.86.4-2.5-2.2-1.3-2.1-2.5-2.2-2.4-2.2-2.1
Bone: periosteal perimeter1.01.72.2-1.5-1.3-0.8-1.3-1.5-1.3-1.5-1.3-1.3
Bone: post-yield work1.72.33.0-1.7-1.5-0.9-1.5-1.7-1.5-1.7-1.5-1.5
Bone: stiffness1.82.84.4-2.1-1.6-0.5-1.5-2.1-1.6-2.0-1.6-1.5
Bone: tissue strength0.00.00.0-0.1-0.00.1-0.0-0.1-0.0-0.0-0.00.2
Bone: trabecular number1.21.82.5-1.2-1.4-1.6-1.4-1.2-1.4-1.1-1.4-1.3
Bone: trabecular spacing0.10.20.80.20.40.90.50.10.40.00.40.3
Bone: trabecular thickness2.83.46.7-1.4-1.9-2.6-2.0-1.4-1.9-1.4-1.9-1.8
Bone: trabecular tissue density0.30.40.7-0.7-0.6-0.1-0.5-0.8-0.5-0.8-0.6-0.7
Breakpoint value in progressive ratio session0.80.91.3-0.8-1.0-1.0-0.9-1.0-0.9-1.0-0.9-1.2
Distance traveled before self-admin6.87.38.0-2.8-2.8-2.3-2.8-2.8-2.8-2.7-2.8-2.5
Distance traveled after self-admin1.92.12.6-1.6-1.6-0.9-1.4-1.6-1.3-1.6-1.4-1.5
Delta time in closed arm before/after self-admin1.01.01.70.81.01.31.00.81.00.91.01.0
Delta time in open arm before/after self-admin4.13.95.4-1.7-2.1-2.3-2.1-1.7-2.1-1.7-2.0-2.0
Diff in mean of infusions in LGA sessions1.61.72.0-1.2-1.4-1.4-1.4-1.2-1.4-1.2-1.4-1.3
Extinction: sum of active levers before priming2.12.23.0-1.4-1.4-1.3-1.4-1.5-1.4-1.5-1.4-1.7
Active lever presses in extinction session 60.50.41.1-0.4-0.7-1.0-0.7-0.5-0.6-0.5-0.6-0.8
Delta distance traveled before/after self-admin0.70.81.20.80.81.10.90.81.00.71.00.7
Delta ambulatory time before/after self-admin1.01.11.61.00.91.31.10.91.20.81.20.9
Time in closed arm before self-admin2.83.23.5-1.7-1.8-1.9-1.9-1.7-1.9-1.6-1.8-1.7
Time in closed arm after self-admin0.20.20.3-0.5-0.4-0.1-0.4-0.5-0.3-0.5-0.4-0.4
Time in open arm before self-admin2.72.84.11.51.82.01.91.41.81.41.71.5
Time in open arm after self-admin2.93.23.6-1.6-1.8-1.9-1.8-1.6-1.9-1.7-1.8-1.9
Sum of active levers in priming session hrs 5-63.03.04.2-1.6-1.8-1.4-1.7-1.8-1.6-1.9-1.6-2.1
Time to tail flick, vehicle, before self-admin0.70.70.80.90.90.70.90.90.90.90.80.9
Time to tail flick, vehicle, after self-admin0.10.10.3-0.3-0.4-0.4-0.4-0.3-0.4-0.4-0.4-0.5
Time to tail flick, test, before self-admin0.90.92.20.70.91.51.00.61.00.61.00.7
Time to tail flick, test, after self-admin1.81.83.41.11.41.81.41.11.31.21.31.4
Delta time to tail flick, vehicle, before/after SA1.00.91.2-0.9-1.0-0.9-1.0-1.0-1.0-1.0-1.0-1.1
Delta time to tail flick, test, before/after SA0.20.20.50.40.40.00.30.60.30.70.20.6
Ambulatory time before self-admin5.45.66.0-2.5-2.4-2.1-2.4-2.4-2.5-2.4-2.5-2.2
Ambulatory time after self-admin0.30.30.5-0.7-0.60.0-0.5-0.7-0.5-0.7-0.5-0.5
Total heroin consumption0.60.71.3-0.6-0.9-1.2-0.9-0.6-0.8-0.6-0.8-1.0
Area under the delay curve0.00.00.00.2-0.0-0.20.10.0-0.00.1-0.0-0.1
Delay disc. indifference point, 0s delay0.00.00.00.1-0.2-0.2-0.10.1-0.10.1-0.10.0
Delay disc. indifference point, 16s delay0.50.50.8-0.5-0.7-0.8-0.7-0.7-0.8-0.7-0.8-0.9
Delay disc. indifference point, 2s delay0.00.00.00.1-0.1-0.10.00.1-0.00.1-0.0-0.0
Delay disc. indifference point, 24s delay0.10.10.20.50.4-0.10.30.40.20.30.20.1
Delay disc. indifference point, 4s delay0.40.40.60.70.50.60.70.70.60.70.60.8
Delay disc. indifference point, 8s delay0.40.40.6-0.5-0.5-0.6-0.5-0.6-0.7-0.6-0.7-0.8
Delay discount exponential model param0.00.00.1-0.3-0.10.2-0.1-0.1-0.0-0.1-0.00.1
Delay discount hyperbolic model param0.00.10.1-0.4-0.2-0.0-0.3-0.3-0.2-0.3-0.2-0.1
Fecal boli incidents, locomotor time 10.10.10.20.30.30.10.30.40.30.40.30.1
Change in fecal boli incidents, locomotor task0.00.00.10.40.2-0.10.10.20.20.20.20.1
Time >=10cm from walls, locomotor time 10.10.10.3-0.3-0.00.60.1-0.3-0.0-0.2-0.00.1
Bouts of movement, locomotor time 11.21.31.41.21.21.11.21.21.21.21.21.0
Total resting periods, locomotor time 11.61.82.01.31.41.41.41.31.41.31.41.2
Rest time, locomotor task time 10.80.91.21.10.90.60.91.10.91.10.90.9
Distance moved, locomotor task time 10.20.30.6-0.4-0.4-0.4-0.4-0.6-0.4-0.6-0.4-0.8
Vertical activity count, locomotor time 10.00.00.1-0.2-0.10.0-0.1-0.2-0.1-0.3-0.1-0.2
Time >=10cm from walls, locomotor time 21.41.42.0-1.1-1.2-1.4-1.3-1.0-1.2-1.1-1.2-1.1
Bouts of movement, locomotor time 23.33.64.11.92.02.02.01.82.01.72.01.7
Total resting periods, locomotor time 23.53.84.32.02.02.02.11.92.01.92.01.8
Rest time, locomotor task time 21.51.82.41.41.31.01.31.51.31.61.31.3
Distance moved, locomotor task time 20.91.01.5-1.0-0.9-0.7-0.9-1.1-0.9-1.2-0.9-1.1
Vertical activity count, locomotor time 20.00.00.00.10.10.10.10.00.1-0.10.10.1
Weight adjusted by age0.60.71.2-1.1-0.8-0.0-0.7-1.0-0.9-1.0-0.8-0.7
Seeking ratio, delayed vs. immediate footshock2.83.23.4-1.8-1.8-1.6-1.8-1.8-1.8-1.8-1.8-1.9
Locomotion in novel chamber1.01.33.40.61.11.81.20.71.00.71.11.4
Locomotion in novel chamber post-restriction0.50.61.60.40.81.20.80.40.70.40.71.0
Progressive ratio0.10.10.20.00.20.50.3-0.10.3-0.20.2-0.1
Food seeking constrained by brief footshock0.10.10.4-0.4-0.00.6-0.0-0.40.1-0.50.0-0.2
Seeking ratio, punishment vs. effort0.00.00.1-0.3-0.20.1-0.2-0.2-0.2-0.2-0.20.0
Run reversals in cocaine runway, females0.10.10.6-0.20.10.80.2-0.20.1-0.10.10.2
Run reversals in cocaine runway, males0.60.61.70.40.81.30.80.40.80.40.80.8
Latency to leave start box in cocaine runway6.57.28.32.62.72.52.72.62.82.62.72.9
Latency to leave start box in cocaine runway, F4.55.06.42.22.21.82.12.32.32.42.22.5
Latency to leave start box in cocaine runway, M1.61.53.01.01.31.71.40.81.30.81.31.1
Cd content in liver1.01.11.5-1.2-1.0-0.5-1.0-1.2-1.0-1.2-1.0-1.0
Co content in liver0.20.30.9-0.1-0.5-0.9-0.5-0.2-0.5-0.3-0.5-0.7
Cu content in liver2.02.43.3-1.3-1.6-1.8-1.6-1.4-1.5-1.4-1.6-1.8
Fe content in liver3.23.85.2-1.7-2.0-2.3-2.0-1.8-2.0-1.8-2.0-2.0
K content in liver1.21.21.80.81.11.31.01.01.11.11.11.3
Mg content in liver1.21.21.81.01.11.01.01.11.11.21.11.3
Mn content in liver0.60.71.20.90.80.40.71.10.81.10.80.9
Na content in liver0.20.20.40.40.40.20.30.50.40.50.40.6
Rb content in liver0.60.72.30.40.91.50.90.40.80.40.90.8
Se content in liver0.10.10.10.20.30.30.30.30.30.30.30.3
Sr content in liver0.20.20.20.50.40.40.40.40.40.40.40.2
Zn content in liver0.80.91.30.81.01.21.00.81.00.81.00.9