Hub : Genes

Znrd2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr1:203018382:203018914 0.05 0.03 4.5e-04 0.01 0.01 0.01 0.01 5.8e-02 1.4e-02 1.6e-02 4.7e-02
2 BLA gene expression ENSRNOG00000012736 0.29 0.11 0.0e+00 0.32 0.32 0.32 0.32 1.9e-17 1.9e-17 2.2e-17 1.4e-17
3 BLA mRNA stability ENSRNOG00000012736 0.14 0.09 7.1e-06 0.1 0.11 0.11 0.11 5.2e-06 1.9e-06 1.2e-06 1.3e-06
4 Brain gene expression ENSRNOG00000012736 0.32 0.11 0.0e+00 0.37 0.38 0.37 0.38 1.9e-35 1.4e-36 4.6e-36 1.4e-36
5 Brain intron excision ratio chr1:203018382:203018677 0.23 0.09 0.0e+00 0.3 0.28 0.3 0.3 1.2e-27 4.3e-26 8.9e-28 7.1e-28
6 Brain intron excision ratio chr1:203018382:203018914 0.34 0.1 0.0e+00 0.43 0.43 0.44 0.44 2.8e-43 7.6e-43 2.9e-44 9.4e-45
7 Brain mRNA stability ENSRNOG00000012736 0.07 0.04 1.1e-05 0.04 0.06 0.05 0.06 3.3e-04 6.3e-06 3.3e-05 6.0e-06
8 IL gene expression ENSRNOG00000012736 0.67 0.15 2.8e-08 0.23 0.29 0.22 0.21 3.5e-06 1.4e-07 6.9e-06 8.9e-06
9 LHb gene expression ENSRNOG00000012736 0.27 0.12 5.4e-06 0.16 0.2 0.18 0.17 1.2e-04 1.6e-05 4.9e-05 7.4e-05
10 Liver gene expression ENSRNOG00000012736 0.05 0.03 2.2e-03 0.02 0.01 0.01 0.01 1.0e-03 2.0e-02 1.5e-02 1.3e-02
11 NAcc gene expression ENSRNOG00000012736 0.24 0.11 4.4e-16 0.18 0.2 0.19 0.2 2.8e-13 6.6e-15 2.0e-14 1.3e-14
12 OFC gene expression ENSRNOG00000012736 0.34 0.15 3.3e-06 0.17 0.14 0.17 0.12 7.2e-05 3.8e-04 8.9e-05 1.1e-03
13 OFC intron excision ratio chr1:203018382:203018914 0.19 0.11 4.4e-03 0.09 0.09 0.08 0.09 3.1e-03 4.5e-03 6.0e-03 3.4e-03
14 PL gene expression ENSRNOG00000012736 0.34 0.12 0.0e+00 0.41 0.41 0.4 0.42 1.2e-33 4.9e-33 1.4e-32 1.4e-34

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail3.210.328.25.1-2.54.1-2.3-2.82.94.7-1.8-0.75.3-1.30.93.0-2.9
BMI without tail1.53.19.42.8-1.52.3-1.2-1.31.32.6-0.7-0.53.1-0.70.61.5-1.6
Body weight3.615.422.24.7-4.04.5-4.0-4.14.24.4-3.9-3.13.0-3.5-2.14.3-4.2
Epididymis fat weight2.55.88.1-1.92.8-2.42.72.8-2.8-1.72.22.7-0.32.72.3-2.52.7
Glucose2.13.15.7-0.71.9-1.22.01.9-1.9-0.61.92.30.92.22.4-1.91.8
Heart weight3.34.76.7-1.82.4-2.12.62.4-2.4-1.92.32.2-0.32.32.0-2.32.5
Left kidney weight0.61.63.1-1.21.4-1.81.21.4-1.4-1.01.21.4-0.61.40.1-1.51.4
Right kidney weight0.20.51.7-0.90.6-1.30.10.6-0.5-0.6-0.10.4-1.00.3-1.1-0.60.5
Tail length0.82.66.80.2-1.70.8-1.6-1.31.30.1-1.9-2.3-1.4-2.1-2.61.4-1.5
Length with tail2.28.112.11.8-3.02.4-3.2-3.03.01.7-3.5-3.4-0.5-3.4-3.43.1-3.0
Length without tail2.55.58.31.9-2.22.3-2.5-2.72.71.8-2.9-2.40.2-2.6-2.12.7-2.4
Liver weight, left0.00.10.2-0.10.4-0.50.30.4-0.3-0.10.00.30.20.20.2-0.40.2
Liver weight, right0.00.10.2-0.00.4-0.10.40.3-0.3-0.3-0.40.0-0.0-0.00.3-0.30.3
Parametrial fat weight2.44.88.2-0.92.3-1.72.32.5-2.4-0.82.42.90.92.72.6-2.52.1
Retroperitoneal fat weight5.116.823.2-3.44.8-4.24.64.6-4.5-3.34.04.5-0.74.53.5-4.44.6
Intraocular pressure1.01.43.9-1.80.8-1.80.71.2-1.1-1.40.40.6-2.00.7-0.4-1.41.0
Extensor digitorum longus weight7.228.935.55.7-5.85.7-5.8-6.05.95.5-5.3-4.82.8-5.2-3.95.9-5.9
Soleus weight3.811.014.6-3.13.7-3.73.73.8-3.8-3.13.13.2-1.33.32.0-3.83.7
Tibialis anterior weight10.636.648.45.2-6.65.6-6.8-6.76.65.1-7.0-6.20.9-6.5-5.86.6-6.6
Tibia length1.13.27.01.0-1.70.9-2.3-1.91.91.4-2.6-1.6-0.7-1.8-2.51.9-1.8
Number of licking bursts0.20.30.40.5-0.50.5-0.7-0.70.70.6-0.5-0.40.2-0.4-0.40.6-0.6
Food consumed during 24 hour testing period0.20.32.2-0.5-0.3-0.2-0.4-0.20.2-0.3-0.4-0.4-1.5-0.4-0.70.2-0.3
Times rat made contact with spout0.40.41.10.7-0.81.1-0.6-0.70.70.70.0-0.60.7-0.50.10.7-0.8
Mean time between licks in bursts0.50.71.70.7-0.91.0-0.6-0.80.80.2-0.9-1.30.2-1.2-0.50.8-0.9
Mean num. licks in bursts0.20.20.7-0.40.4-0.20.60.5-0.5-0.40.80.30.10.50.8-0.50.5
Std. dev. time between licks in bursts0.10.10.6-0.30.2-0.20.30.3-0.2-0.8-0.2-0.5-0.2-0.4-0.3-0.30.2
Water consumed over 24 hours0.60.81.30.5-1.11.1-1.0-1.01.00.6-0.5-1.1-0.3-1.0-0.41.0-1.1
Indifference point 0 sec0.00.10.1-0.10.2-0.30.30.2-0.2-0.10.40.30.00.30.4-0.30.2
Indifference point AUC3.33.95.61.6-2.21.8-2.3-2.22.21.8-2.0-1.90.5-2.0-1.72.4-2.3
Indifference point function ln k7.710.815.1-2.93.7-3.43.93.8-3.8-3.33.32.9-1.03.12.2-3.83.8
Indifference point function log k7.710.815.1-2.93.7-3.43.93.8-3.8-3.33.32.9-1.03.12.2-3.83.8
Delay discounting total patch changes 0 sec0.00.00.1-0.20.1-0.30.20.2-0.1-0.30.1-0.0-0.30.0-0.0-0.20.1
Delay discounting total patch changes 12 sec4.45.98.12.4-2.72.6-2.7-2.82.92.5-2.1-2.11.3-2.2-1.52.9-2.8
Delay discounting total patch changes 18 sec0.50.71.31.0-0.90.9-0.9-0.90.91.1-0.6-0.40.8-0.5-0.21.0-1.0
Delay discounting total patch changes 24 sec2.53.14.21.3-2.01.6-2.0-2.02.01.3-2.0-1.9-0.1-2.0-1.61.8-2.0
Delay discounting total patch changes 6 sec0.91.42.41.3-1.21.3-1.1-1.51.51.2-1.0-1.00.8-1.1-0.41.5-1.3
Delay discounting time to switch 0 sec1.82.86.52.5-1.32.1-1.5-1.71.72.5-0.9-0.42.3-0.70.21.6-1.7
Delay discounting water rate 0 sec3.96.211.4-3.42.2-3.22.42.7-2.7-3.31.61.3-2.91.60.1-2.62.6
Delay discounting water rate 12 sec8.012.020.0-4.33.4-3.93.73.9-3.9-4.52.72.0-3.22.41.3-3.93.8
Delay discounting water rate 18 sec2.83.85.8-2.22.0-2.02.32.1-2.1-2.41.61.3-1.51.51.0-2.22.3
Delay discounting water rate 24 sec3.85.38.1-2.82.3-2.72.52.6-2.6-2.81.51.4-2.11.60.5-2.72.6
Delay discounting water rate 6 sec3.55.19.9-2.82.2-2.62.52.4-2.4-3.11.51.1-2.41.40.4-2.52.5
Locomotor activity1.62.55.8-2.11.7-1.81.81.6-1.6-2.41.00.7-1.70.90.2-1.61.9
Locomotor testing distance2.23.67.9-2.42.0-2.02.22.0-2.1-2.81.30.8-1.81.00.5-1.92.3
Locomotor testing rearing2.03.25.1-2.01.9-1.52.11.9-2.0-2.31.61.0-1.41.31.6-1.72.1
Light reinforcement 10.20.30.6-0.80.4-0.60.50.6-0.6-0.80.50.1-0.70.30.3-0.50.4
Light reinforcement 20.91.22.6-1.31.2-1.60.81.2-1.2-0.90.41.1-1.11.00.3-1.11.2
Reaction time number correct0.50.71.60.2-0.80.5-0.8-0.60.60.3-1.2-1.1-0.6-1.1-1.30.8-0.7
Reaction time mean minus median2.83.75.51.9-2.11.9-2.4-2.12.22.1-1.9-1.50.9-1.6-1.42.1-2.2
Reaction time mean minus median AUC1.62.13.21.1-1.61.2-1.8-1.61.61.2-1.6-1.30.2-1.4-1.61.6-1.6
Reaction time num false alarms0.20.31.0-0.50.5-0.60.70.5-0.4-1.00.5-0.0-0.30.1-0.3-0.40.6
Reaction time num false alarms AUC0.10.10.50.1-0.20.00.0-0.20.3-0.4-0.1-0.60.1-0.5-0.70.3-0.1
Reaction time trials correct on left0.50.71.60.2-0.80.5-0.8-0.60.60.3-1.2-1.1-0.6-1.1-1.30.8-0.7
Reaction time trials on left0.60.82.00.3-0.90.5-0.9-0.70.70.3-1.3-1.2-0.7-1.2-1.40.9-0.8
Reaction time mean0.00.00.20.0-0.3-0.1-0.4-0.20.20.30.10.10.10.1-0.10.1-0.4
Reaction time mean AUC0.00.10.20.1-0.3-0.1-0.3-0.10.10.40.30.20.30.20.00.0-0.3
Median of all reaction times0.10.10.4-0.30.1-0.40.10.3-0.30.00.60.50.10.50.4-0.40.1
Reaction time omissions1.21.62.41.2-1.51.2-1.5-1.41.41.3-1.0-1.20.6-1.2-1.21.5-1.3
Reaction time false alarm rate0.20.20.6-0.30.6-0.50.70.4-0.3-0.80.60.20.20.30.0-0.40.6
Reaction time premature initiation rate2.33.15.41.5-2.12.0-1.8-1.81.81.0-1.8-2.30.3-2.2-1.31.7-2.0
Reaction time premature initiations3.85.59.51.6-2.82.3-2.5-2.32.31.3-2.6-3.1-0.1-3.0-2.22.4-2.5
Std. dev. reaction times0.70.91.80.8-1.20.8-1.3-1.11.11.1-0.9-0.70.4-0.8-0.81.0-1.2
Reaction time trials completed0.60.82.00.3-0.90.5-0.9-0.70.70.3-1.3-1.2-0.7-1.2-1.40.9-0.8
Reaction time trials AUC0.40.51.30.2-0.70.4-0.7-0.50.50.2-1.1-1.0-0.6-1.0-1.10.7-0.6
Social response proportion0.80.81.30.9-1.01.1-1.1-1.01.10.9-1.0-0.80.5-0.8-0.20.9-1.1
Social responses0.30.30.60.2-0.50.5-0.6-0.60.60.1-0.8-0.8-0.5-0.7-0.40.7-0.5
Social time0.40.51.10.3-0.70.8-0.7-0.80.70.2-1.0-1.0-0.5-1.0-0.60.7-0.6
Conditioned locomotion1.72.02.81.3-1.61.4-1.5-1.51.51.1-1.7-1.50.1-1.6-1.41.4-1.5
Cocaine response after cond. corrected1.31.42.4-1.01.4-1.11.61.4-1.4-1.31.11.0-0.21.10.8-1.41.4
Cocaine response after cond. not corrected1.01.11.9-0.81.2-1.01.41.2-1.2-1.10.90.9-0.20.90.9-1.31.3
Cocaine response before conditioning0.60.71.10.7-1.00.7-1.0-0.91.00.9-0.9-0.70.1-0.7-0.51.0-0.9
Saline control response3.95.27.02.3-2.52.7-2.3-2.52.52.0-2.4-2.30.7-2.4-1.22.5-2.6
Condit. Reinf. active minus inactive responses0.10.10.5-0.20.3-0.30.30.2-0.3-0.00.40.7-0.00.60.5-0.30.4
Condit. Reinf. active-inactive response ratio0.50.61.7-0.50.8-1.00.70.7-0.7-0.20.41.30.11.10.4-0.70.9
Condit. Reinf. active responses0.10.20.60.4-0.20.5-0.1-0.30.20.50.40.30.50.30.80.3-0.1
Condit. Reinf. inactive responses0.40.51.60.8-0.51.3-0.4-0.60.60.70.3-0.30.8-0.21.00.6-0.6
Condit. Reinf. lever presses2.02.84.41.6-1.71.6-1.9-2.12.01.8-1.8-1.20.5-1.4-1.02.1-1.8
Condit. Reinf. lever reinforcers received0.20.30.70.6-0.60.8-0.5-0.70.60.8-0.0-0.10.4-0.10.40.6-0.5
Pavlov. Cond. lever latency0.50.71.2-0.80.7-0.71.01.0-0.9-0.91.10.5-0.20.70.6-0.90.8
Pavlov. Cond. magazine entry latency3.54.05.92.2-2.02.3-2.1-2.42.32.2-1.5-1.51.7-1.6-1.02.4-2.1
Pavlov. Cond. change in total contacts1.72.34.01.6-1.61.5-1.9-1.91.82.0-1.2-0.81.2-1.0-0.81.9-1.6
Pavlov. Cond. index score2.33.04.51.9-1.71.7-2.0-2.12.02.0-1.6-1.11.2-1.3-1.12.1-1.8
Pavlov. Cond. latency score1.92.43.61.7-1.51.5-1.8-1.91.81.9-1.5-1.01.2-1.2-1.01.9-1.6
Pavlov. Cond. lever contacts0.50.71.60.5-0.80.5-1.0-1.00.90.6-1.3-0.8-0.4-0.9-1.01.0-0.9
Pavlov. Cond. magazine entry number6.07.410.6-2.82.9-3.03.13.2-3.2-3.02.22.1-1.82.31.6-3.23.0
Pavlov. Cond. intertrial magazine entries1.11.52.0-1.21.3-1.41.31.4-1.4-1.20.91.1-0.81.10.7-1.41.4
Pavlov. Cond. lever-magazine prob. diff.2.83.65.32.0-1.92.0-2.2-2.32.22.2-1.7-1.31.3-1.5-1.22.3-2.0
Pavlov. Cond. response bias1.72.33.41.4-1.61.4-1.8-1.81.81.5-1.6-1.20.4-1.4-1.11.8-1.7
Conditioned reinforcement - actives0.30.30.8-0.80.4-0.80.20.3-0.4-0.7-0.20.3-0.90.3-0.2-0.30.5
Conditioned reinforcement - inactives5.86.69.8-3.02.7-3.12.62.7-2.6-2.62.42.5-1.82.61.5-2.52.8
Conditioned locomotion7.89.314.4-3.63.1-3.83.13.3-3.3-3.42.62.6-2.42.81.4-3.23.3
Intermittent access intake day 1-15 change0.80.82.2-1.40.7-1.40.50.7-0.7-1.30.20.4-1.50.5-0.6-0.70.8
Intermittent access intake escalation0.60.61.4-1.20.7-1.20.60.6-0.7-1.10.40.6-1.00.6-0.3-0.70.8
Intermittent access intake escalation 20.40.41.5-1.00.1-0.90.00.4-0.4-0.8-0.00.0-1.20.1-0.8-0.40.3
Intermitt. access day 1 inactive lever presses2.52.73.7-1.61.9-1.81.71.8-1.7-1.31.81.7-0.61.81.1-1.81.8
Intermitt. access day 15 inactive lever presses2.32.53.9-1.82.0-2.01.61.4-1.4-1.51.41.8-1.01.80.6-1.51.8
Intermitt. access escalation Index3.53.15.4-1.02.0-1.32.21.8-1.8-1.12.32.00.42.12.2-1.71.8
Intermittent access day 1 total infusions5.86.512.9-1.22.9-1.93.02.4-2.5-1.32.73.40.73.33.6-2.42.6
Intermittent access day 15 total infusions7.58.411.4-2.73.2-3.23.22.9-3.0-2.62.63.4-1.03.32.5-2.93.3
Intermittent access terminal intake (last 3 days)5.25.79.0-2.02.7-2.52.62.3-2.4-1.92.03.0-0.62.92.3-2.42.6
Intermittent access total infusions4.44.99.2-1.52.5-2.02.62.0-2.1-1.52.23.00.12.92.7-2.02.4
Intermittent access day 1 locomotion4.24.29.3-0.72.3-1.32.51.8-1.9-0.92.32.81.02.63.1-1.82.1
Intermittent access day 15 total locomotion4.75.07.3-2.02.4-2.42.52.1-2.2-1.92.22.7-0.62.72.0-2.12.5
Intermittent access total locomotion6.27.013.2-1.62.9-2.33.02.5-2.6-1.42.73.60.43.43.3-2.52.8
Intermittent access standard deviation1.21.32.2-1.51.1-1.51.01.1-1.1-1.40.70.9-1.21.00.2-1.11.2
Cocaine induced anxiety0.00.00.2-0.10.0-0.2-0.20.1-0.1-0.1-0.4-0.0-0.3-0.1-0.3-0.10.1
Post-drug Anxiety1.41.53.80.7-1.20.7-1.5-1.11.20.8-2.0-1.4-0.4-1.5-1.61.1-1.2
Baseline Anxiety2.62.83.71.3-1.71.4-1.8-1.91.91.2-1.9-1.90.2-1.9-1.91.8-1.7
Lifetime Intake3.94.48.3-1.22.4-1.82.51.8-2.0-1.32.12.90.42.72.7-1.82.3
Incentive Sensitization - Responses0.40.40.9-0.60.7-0.70.60.4-0.5-0.50.60.9-0.10.90.4-0.40.7
Incentive Sensitization - Breakpoint0.60.61.2-0.80.9-1.00.80.6-0.7-0.70.71.1-0.31.00.4-0.50.8
Progressive ratio test 1 active lever presses2.82.93.7-1.71.9-1.81.91.6-1.7-1.71.71.8-0.81.91.5-1.61.9
Progressive ratio test 1 breakpoint2.52.63.2-1.71.8-1.81.81.5-1.6-1.71.51.7-0.91.71.3-1.51.8
Progressive ratio test 1 inactive lever presses1.31.42.4-1.01.3-1.11.41.1-1.1-1.11.51.3-0.21.31.3-1.11.2
Progressive ratio test 2 active lever presses4.04.25.9-2.12.2-2.32.31.9-2.1-2.01.92.4-0.92.41.7-1.92.3
Progressive ratio test 2 breakpoint5.05.67.9-2.62.5-2.82.62.3-2.4-2.52.12.5-1.42.51.5-2.32.6
Progressive ratio test 2 inactive lever presses8.59.813.2-2.93.4-3.33.43.1-3.2-2.73.33.6-1.03.63.0-3.13.3
Total sessions with >9 infusions1.71.83.2-0.61.6-1.11.81.2-1.3-0.81.31.80.51.71.8-1.21.5
Short access day 1 total inactive lever presses3.64.05.5-1.72.1-2.02.42.1-2.1-1.52.32.3-0.32.31.9-2.02.2
Short access day 10 total inactive lever presses3.53.95.3-1.92.2-2.12.32.1-2.1-1.92.31.8-0.81.91.4-2.12.2
Short access day 1 total infusions3.23.36.9-0.61.9-1.22.21.7-1.8-0.62.22.50.92.42.6-1.51.8
Short access day 10 total infusions2.22.47.90.21.6-0.41.70.8-1.00.11.72.41.72.12.8-0.71.4
Short access total infusions1.61.74.9-0.11.4-0.71.61.0-1.1-0.31.41.91.01.82.2-0.91.3
Short access day 1 locomotion2.42.54.8-0.71.7-1.12.11.2-1.3-0.81.82.20.72.12.2-1.31.8
Short access day 10 total locomotion1.92.04.3-0.41.6-0.81.71.1-1.2-0.41.82.00.91.92.1-1.11.5
Short access total locomotion1.61.63.9-0.21.3-0.71.60.9-1.0-0.31.61.80.91.72.0-0.91.3
Compulsive drug intake2.42.44.61.1-1.71.7-1.6-1.61.61.0-1.2-2.10.1-2.0-1.31.6-1.7
One hour access (0.3 mA shock)9.711.213.9-3.43.7-3.73.73.4-3.5-3.43.03.5-1.73.62.6-3.43.7
One hour access (shock baseline)8.49.713.3-3.23.3-3.63.33.2-3.3-2.92.73.5-1.53.52.2-3.23.5
Number of responses in last shaping day1.21.22.0-1.31.0-1.31.31.1-1.1-1.41.00.8-0.90.90.6-1.11.3
Context. condit. distance diff. score1.92.33.1-1.21.7-1.51.81.7-1.6-1.21.71.5-0.31.61.2-1.81.6
Locomotion velocity, session 10.10.10.2-0.0-0.20.1-0.0-0.00.0-0.2-0.4-0.5-0.2-0.4-0.50.1-0.1
Locomotion distance, session 10.70.92.61.5-0.61.4-0.4-0.90.81.3-0.3-0.21.6-0.30.50.8-0.7
Locomotion velocity, session 22.83.25.12.3-1.72.1-1.8-2.01.92.1-1.6-1.41.7-1.5-0.92.0-1.9
Locomotion distance, session 20.81.22.81.6-0.81.7-0.7-1.11.01.4-0.4-0.51.7-0.60.21.1-0.9
Locomotion velocity, session 30.20.31.30.50.6-0.00.60.2-0.20.30.30.71.10.60.7-0.20.4
Locomotion distance, session 30.00.00.1-0.10.2-0.10.20.1-0.1-0.20.10.20.10.10.1-0.10.2
Stereotopy head waving bouts, day 30.70.82.20.20.9-0.21.11.0-1.0-0.10.61.01.00.91.5-1.00.8
Stereotopy head waving duration, day 30.81.02.1-0.31.0-0.61.11.2-1.2-0.40.81.10.41.11.5-1.21.0
Locomotion velocity, session 70.80.92.90.50.9-0.10.90.4-0.50.51.21.41.71.31.3-0.50.8
Locomotion distance, session 70.20.21.30.50.30.20.50.0-0.10.30.60.51.20.40.60.00.3
Stereotopy head waving bouts, day 70.20.30.8-0.00.4-0.30.30.5-0.50.20.50.80.50.80.9-0.50.4
Stereotopy head waving duration, day 70.81.02.41.4-1.01.3-1.0-1.01.01.5-0.6-0.31.3-0.40.30.9-1.1
Locomotion velocity, session 81.01.22.20.8-1.01.1-1.0-1.21.20.5-1.5-1.4-0.1-1.5-0.81.2-1.1
Locomotion distance, session 80.20.30.70.30.7-0.20.70.5-0.50.20.50.80.80.70.7-0.50.5
Degree of sensitization distance0.20.21.10.60.20.40.3-0.00.00.40.20.41.10.30.60.00.1
Degree of sensitization stereotypy0.40.41.00.8-0.60.6-0.8-0.70.71.0-0.4-0.10.7-0.2-0.10.7-0.7
Condit. Reinf. active minus inactive responses0.20.20.40.6-0.50.6-0.3-0.50.50.50.0-0.20.5-0.2-0.20.5-0.4
Condit. Reinf. active-inactive response ratio0.00.00.10.1-0.30.2-0.1-0.20.20.10.4-0.10.10.0-0.10.1-0.1
Condit. Reinf. active responses0.10.10.40.6-0.20.2-0.1-0.40.30.50.00.20.70.1-0.20.4-0.2
Condit. Reinf. inactive responses0.10.10.50.40.4-0.20.20.1-0.10.4-0.00.60.70.40.10.10.2
Incentive salience index mean0.40.51.21.1-0.60.8-0.5-0.70.61.0-0.2-0.11.0-0.2-0.20.7-0.6
Condit. Reinf. lever presses0.40.51.11.0-0.60.5-0.7-0.70.71.0-0.8-0.30.5-0.5-0.70.7-0.7
Time in familiar zone, hab. session 10.30.30.5-0.00.6-0.40.60.5-0.4-0.10.50.70.40.60.6-0.40.5
Time in novel zone, hab. session 10.20.20.8-0.80.2-0.40.40.5-0.5-0.90.2-0.2-0.8-0.1-0.1-0.50.4
Total zone transitions, hab. session 10.70.91.51.1-1.01.1-1.0-1.21.21.1-0.5-0.70.8-0.7-0.61.2-1.0
Total locomotion distance, hab. session 10.30.40.90.00.6-0.40.70.7-0.70.00.81.00.70.90.6-0.70.6
Locomotion velocity, hab. session 10.10.10.60.40.20.10.20.2-0.20.40.30.50.80.40.2-0.20.2
Time in familiar zone, hab. session 20.10.10.4-0.30.1-0.00.20.1-0.1-0.6-0.4-0.5-0.5-0.5-0.3-0.10.1
Time in novel zone, hab. session 20.20.21.00.5-0.30.4-0.3-0.20.20.70.50.31.00.30.40.2-0.2
Total zone transitions, hab. session 21.92.46.42.3-1.22.4-0.9-1.31.32.2-0.4-0.32.5-0.51.31.3-1.3
Total locomotion distance, hab. session 20.50.73.51.10.20.80.40.2-0.20.90.60.81.90.71.4-0.20.1
Locomotion velocity, hab. session 20.50.73.00.90.40.50.60.4-0.40.80.71.01.70.91.5-0.40.3
Novel to familiar place preference ratio0.90.92.01.0-1.20.9-1.3-1.11.11.4-0.7-0.50.7-0.6-0.51.1-1.2
Novelty place preference0.40.41.10.7-0.70.5-0.9-0.60.61.0-0.3-0.10.6-0.2-0.10.6-0.7
Time in novel zone, NPP test0.30.30.80.6-0.60.4-0.7-0.50.50.9-0.2-0.10.5-0.2-0.00.5-0.6
Total zone transitions, NPP test2.23.15.22.3-1.92.3-1.8-1.91.92.2-1.3-1.21.6-1.4-0.41.9-1.9
Total locomotion distance, NPP test0.20.31.70.9-0.10.6-0.1-0.20.20.80.20.21.30.10.20.2-0.2
Locomotion velocity, NPP test0.20.31.60.9-0.20.6-0.2-0.20.20.90.20.21.30.10.10.3-0.3
Pavlov. Cond. lever latency0.30.30.9-0.90.5-0.70.50.5-0.5-0.80.50.2-0.60.30.2-0.50.6
Pavlov. Cond. magazine entry latency0.30.41.71.0-0.50.8-0.3-0.30.31.10.30.31.30.20.60.2-0.5
Pavlov. Cond. change in total contacts0.10.10.50.5-0.20.1-0.3-0.10.10.70.30.40.70.3-0.00.2-0.2
Pavlov. Cond. index score0.10.10.30.5-0.50.4-0.5-0.30.30.6-0.2-0.10.2-0.2-0.30.3-0.4
Pavlov. Cond. latency score0.10.10.30.5-0.30.4-0.3-0.10.10.5-0.00.00.4-0.0-0.00.1-0.3
Pavlov. Cond. lever contacts0.00.00.20.4-0.10.2-0.10.00.00.3-0.00.10.20.0-0.00.0-0.1
Pavlov. Cond. magazine entry number0.20.20.6-0.30.6-0.30.80.5-0.5-0.50.30.30.10.40.7-0.50.6
Pavlov. Cond. intertrial magazine entries0.50.61.4-1.20.7-1.20.60.5-0.5-1.10.60.5-1.00.6-0.4-0.40.8
Pavlov. Cond. lever-magazine prob. diff.0.30.30.80.8-0.70.6-0.7-0.50.50.9-0.3-0.30.5-0.3-0.40.5-0.7
Pavlov. Cond. response bias0.10.10.20.2-0.40.1-0.5-0.30.30.4-0.1-0.1-0.1-0.2-0.50.3-0.3
Bone: apparent density0.71.13.81.6-0.21.4-0.4-0.80.81.6-0.20.31.90.11.30.8-0.6
Bone surface3.76.510.43.1-2.53.1-2.7-2.82.93.2-2.6-1.51.9-1.9-0.42.8-2.7
Bone volume1.42.35.22.1-1.21.8-1.5-1.61.72.3-1.3-0.31.7-0.70.41.6-1.5
Bone: connectivity density2.13.36.52.5-1.52.5-1.6-2.02.02.5-1.3-0.82.1-1.00.62.0-1.8
Bone: cortical apparent density0.20.30.60.3-0.80.5-0.6-0.60.60.30.1-0.60.5-0.5-0.60.6-0.7
Bone: cortical area0.81.12.20.8-0.80.6-1.2-1.31.20.9-1.5-0.9-0.1-1.1-1.51.3-0.9
Bone: cortical porosity0.20.20.90.7-0.20.7-0.1-0.20.20.70.10.20.90.10.70.2-0.2
Bone: cortical porosity0.60.61.51.1-0.71.2-0.7-0.70.71.0-0.4-0.41.0-0.50.30.7-0.8
Bone: cortical thickness2.94.99.31.3-2.21.6-2.4-2.52.51.2-2.3-2.6-0.4-2.6-3.12.5-2.2
Bone: cortical thickness0.80.92.40.2-0.80.5-0.8-1.00.90.0-0.9-1.4-0.5-1.3-1.51.0-0.8
Bone: cortical tissue density0.30.40.90.3-0.90.6-0.7-0.70.70.40.0-0.70.5-0.6-0.60.6-0.8
Bone: elastic displacement1.11.33.5-1.61.0-1.21.11.0-1.0-1.90.50.0-1.80.2-0.5-1.01.2
Bone: elastic work0.81.12.30.5-1.00.8-0.9-1.11.10.2-1.2-1.5-0.5-1.5-1.51.1-0.9
Bone: endosteal estimation0.92.04.50.01.7-0.81.51.4-1.4-0.00.92.01.21.82.1-1.41.5
Bone: endosteal perimeter1.12.35.5-0.31.9-1.01.61.5-1.5-0.10.92.30.82.02.4-1.51.6
Bone: final force2.84.65.82.3-2.22.3-2.3-2.42.42.3-2.4-1.81.0-2.0-1.52.3-2.3
Bone: final moment2.44.05.32.2-2.02.1-2.2-2.22.22.2-2.3-1.71.0-1.9-1.42.2-2.2
Bone: marrow area1.02.14.80.01.7-0.81.61.5-1.5-0.10.92.11.31.82.2-1.51.5
Bone: maximum diameter0.20.41.90.4-0.30.1-0.7-0.50.50.5-1.4-0.3-0.4-0.5-0.80.5-0.4
Bone: maximum force3.35.79.53.1-2.22.7-2.4-2.62.63.1-2.3-1.42.1-1.7-0.82.6-2.5
Bone: maximum moment2.84.88.22.9-2.02.5-2.2-2.42.42.9-2.2-1.22.0-1.6-0.82.4-2.3
Bone: minimum diameter1.12.05.10.31.5-0.51.41.1-1.10.31.42.11.81.92.3-1.11.3
Bone: periosteal estimation0.10.20.40.50.5-0.10.10.0-0.10.5-0.50.60.60.40.2-0.00.3
Bone: periosteal perimeter0.10.20.60.7-0.00.4-0.4-0.40.40.8-0.80.10.4-0.10.20.4-0.2
Bone: post-yield work2.12.813.42.6-0.21.4-0.4-0.60.62.80.31.53.71.12.10.6-0.7
Bone: stiffness2.64.17.62.6-1.92.3-2.1-2.22.22.8-1.7-1.02.0-1.3-0.42.2-2.2
Bone: tissue strength0.00.00.10.2-0.10.2-0.2-0.20.20.3-0.10.10.10.00.10.2-0.2
Bone: trabecular number0.60.92.21.3-0.41.3-0.6-0.91.01.5-0.40.21.4-0.01.01.0-0.7
Bone: trabecular spacing0.20.20.6-0.60.3-0.50.60.6-0.6-0.80.60.1-0.10.2-0.0-0.60.5
Bone: trabecular thickness0.70.82.3-0.21.2-0.40.90.6-0.6-0.11.11.30.51.21.5-0.60.9
Bone: trabecular tissue density3.34.66.4-2.42.4-2.52.22.4-2.4-2.31.91.9-1.32.00.6-2.42.3
Breakpoint value in progressive ratio session3.03.34.81.7-1.81.7-2.2-2.02.11.7-1.8-1.60.7-1.8-1.72.2-2.0
Distance traveled before self-admin0.50.50.90.7-0.80.7-1.0-0.70.70.9-0.8-0.50.3-0.6-0.50.7-0.9
Distance traveled after self-admin0.20.20.40.3-0.50.3-0.6-0.50.50.6-0.4-0.40.0-0.4-0.50.5-0.5
Delta time in closed arm before/after self-admin0.10.10.30.2-0.10.50.2-0.20.2-0.3-0.2-0.50.1-0.5-0.10.2-0.0
Delta time in open arm before/after self-admin0.10.10.2-0.2-0.2-0.2-0.5-0.20.20.3-0.2-0.1-0.5-0.1-0.50.1-0.3
Diff in mean of infusions in LGA sessions0.40.51.00.2-0.70.4-0.8-0.70.70.5-0.8-0.9-0.4-0.9-1.00.9-0.6
Extinction: sum of active levers before priming4.44.46.82.5-2.12.3-2.3-2.32.32.6-1.6-1.51.8-1.7-1.22.4-2.3
Active lever presses in extinction session 62.82.75.50.9-1.61.1-2.0-1.61.61.0-2.3-1.8-0.6-1.9-2.21.7-1.6
Delta distance traveled before/after self-admin0.00.00.1-0.30.2-0.20.2-0.00.0-0.20.1-0.1-0.3-0.1-0.1-0.00.3
Delta ambulatory time before/after self-admin0.00.00.1-0.20.1-0.00.1-0.10.1-0.20.0-0.3-0.3-0.2-0.20.00.2
Time in closed arm before self-admin0.00.00.20.2-0.00.0-0.3-0.10.10.5-0.20.20.20.10.10.0-0.2
Time in closed arm after self-admin0.00.00.20.20.3-0.00.30.1-0.1-0.10.20.20.40.10.2-0.10.2
Time in open arm before self-admin0.50.51.5-0.50.5-0.21.10.7-0.7-1.01.20.30.10.50.7-0.60.8
Time in open arm after self-admin0.20.30.8-0.90.2-0.50.30.5-0.5-0.90.5-0.0-0.90.1-0.1-0.50.4
Sum of active levers in priming session hrs 5-62.42.37.50.1-1.40.2-1.8-1.41.40.5-2.2-1.6-1.4-1.6-2.71.4-1.2
Time to tail flick, vehicle, before self-admin0.50.51.11.1-0.80.8-0.6-0.60.60.9-0.6-0.20.9-0.30.10.6-0.8
Time to tail flick, vehicle, after self-admin1.31.43.31.8-1.11.7-0.9-1.21.11.2-0.9-0.81.6-0.90.01.1-1.2
Time to tail flick, test, before self-admin1.00.92.70.21.0-0.11.20.6-0.7-0.21.11.31.21.21.6-0.70.8
Time to tail flick, test, after self-admin0.00.00.2-0.1-0.40.0-0.2-0.00.0-0.2-0.3-0.3-0.3-0.2-0.20.0-0.1
Delta time to tail flick, vehicle, before/after SA0.40.41.10.9-0.51.0-0.4-0.70.70.6-0.4-0.50.9-0.50.00.6-0.6
Delta time to tail flick, test, before/after SA1.91.74.2-0.2-1.50.3-1.6-0.90.9-0.2-1.6-1.8-1.6-1.7-2.00.9-1.1
Ambulatory time before self-admin0.30.30.70.5-0.60.4-0.9-0.70.70.7-0.8-0.30.1-0.4-0.50.3-0.7
Ambulatory time after self-admin0.10.10.4-0.00.3-0.20.10.3-0.20.50.50.70.40.60.5-0.20.3
Total heroin consumption5.46.58.72.5-2.92.7-2.9-2.82.82.5-2.3-2.41.2-2.5-2.03.0-2.8
Area under the delay curve0.40.41.60.40.20.40.50.3-0.30.31.00.61.10.71.3-0.20.3
Delay disc. indifference point, 0s delay0.80.93.10.10.70.11.00.9-1.0-0.11.31.01.21.01.7-0.90.6
Delay disc. indifference point, 16s delay1.11.12.6-0.61.1-0.81.10.9-0.9-0.31.61.40.81.41.2-0.81.1
Delay disc. indifference point, 2s delay0.10.10.4-0.00.2-0.20.40.4-0.4-0.10.30.50.30.40.60.10.4
Delay disc. indifference point, 24s delay0.10.10.2-0.30.1-0.10.30.3-0.3-0.50.5-0.1-0.00.10.2-0.40.4
Delay disc. indifference point, 4s delay0.30.41.60.10.40.20.70.5-0.5-0.10.90.50.70.61.2-0.30.5
Delay disc. indifference point, 8s delay0.20.21.00.20.20.40.40.3-0.30.10.70.30.60.41.0-0.40.2
Delay discount exponential model param0.30.31.1-0.3-0.1-0.4-0.4-0.30.3-0.2-0.8-0.5-0.9-0.5-1.10.1-0.3
Delay discount hyperbolic model param0.20.21.0-0.3-0.0-0.4-0.3-0.20.2-0.2-0.7-0.4-0.9-0.4-1.00.0-0.2
Fecal boli incidents, locomotor time 10.10.10.3-0.0-0.1-0.3-0.5-0.10.10.4-0.50.2-0.20.0-0.60.4-0.1
Change in fecal boli incidents, locomotor task0.10.10.60.60.20.60.3-0.00.00.10.0-0.10.8-0.10.6-0.30.0
Time >=10cm from walls, locomotor time 11.01.03.00.11.0-0.60.90.9-0.80.20.61.70.91.41.6-0.90.8
Bouts of movement, locomotor time 11.21.32.50.7-1.61.3-1.5-1.41.31.1-0.5-1.20.1-1.1-1.11.0-1.3
Total resting periods, locomotor time 10.80.91.80.6-1.41.1-1.3-1.11.11.0-0.3-0.90.2-0.8-0.80.9-1.1
Rest time, locomotor task time 11.21.32.0-1.41.2-1.41.11.3-1.3-1.40.60.8-1.20.80.3-1.21.3
Distance moved, locomotor task time 10.30.31.30.8-0.20.6-0.1-0.50.40.70.20.21.20.10.60.4-0.2
Vertical activity count, locomotor time 11.21.31.7-1.11.2-1.31.31.2-1.2-1.11.21.1-0.41.20.8-1.21.3
Time >=10cm from walls, locomotor time 20.00.00.10.2-0.10.1-0.3-0.10.00.30.00.20.10.2-0.0-0.2-0.2
Bouts of movement, locomotor time 20.40.40.70.5-0.80.8-0.8-0.80.80.70.0-0.60.5-0.5-0.20.6-0.8
Total resting periods, locomotor time 20.20.20.40.4-0.40.6-0.5-0.60.60.50.3-0.20.6-0.20.10.3-0.5
Rest time, locomotor task time 22.32.74.1-1.42.0-1.61.81.9-1.9-1.41.51.7-0.41.71.4-2.01.8
Distance moved, locomotor task time 21.11.31.80.9-1.41.1-1.3-1.41.30.8-1.1-1.20.1-1.2-1.11.3-1.2
Vertical activity count, locomotor time 20.40.41.8-0.7-0.2-0.4-0.0-0.00.1-0.8-0.5-0.8-1.3-0.7-1.1-0.00.1
Weight adjusted by age2.32.63.61.3-1.91.6-1.9-1.91.81.3-1.9-1.60.1-1.7-1.81.5-1.5
Seeking ratio, delayed vs. immediate footshock0.20.31.00.30.20.30.30.1-0.00.31.00.50.90.60.8-0.10.2
Locomotion in novel chamber4.35.37.7-2.42.6-2.82.42.4-2.5-2.11.82.4-1.42.41.3-2.52.6
Locomotion in novel chamber post-restriction2.93.44.8-1.92.2-2.22.01.9-1.9-1.81.71.9-0.81.91.2-1.92.1
Progressive ratio2.42.86.52.5-1.32.4-1.4-1.51.52.4-0.9-0.42.5-0.70.61.5-1.6
Food seeking constrained by brief footshock0.20.20.50.3-0.20.5-0.3-0.60.60.1-0.4-0.70.0-0.7-0.40.7-0.4
Seeking ratio, punishment vs. effort1.82.25.1-2.21.4-1.91.51.4-1.4-2.31.10.4-2.00.6-0.2-1.41.5
Run reversals in cocaine runway, females0.90.94.41.6-0.41.2-0.1-0.60.61.30.10.02.1-0.10.80.6-0.6
Run reversals in cocaine runway, males0.80.83.1-1.20.5-1.10.30.4-0.4-1.4-0.4-0.3-1.8-0.3-1.2-0.10.5
Latency to leave start box in cocaine runway0.20.31.20.50.50.10.3-0.10.00.50.50.71.10.60.8-0.00.2
Latency to leave start box in cocaine runway, F0.10.20.70.40.10.30.0-0.20.20.50.60.40.90.40.50.0-0.0
Latency to leave start box in cocaine runway, M0.00.00.20.30.4-0.10.1-0.10.10.1-0.40.20.3-0.0-0.00.10.2
Cd content in liver1.41.53.0-1.71.2-1.51.01.2-1.2-1.50.70.9-1.61.00.1-1.31.2
Co content in liver1.51.84.0-1.91.0-1.41.31.4-1.4-2.01.50.3-1.60.70.2-1.41.3
Cu content in liver0.30.30.80.7-0.40.5-0.6-0.70.70.80.1-0.20.9-0.2-0.10.7-0.5
Fe content in liver0.20.20.80.3-0.40.1-0.5-0.40.40.2-0.9-0.4-0.3-0.5-0.60.5-0.3
K content in liver1.81.84.12.0-1.11.6-1.1-1.41.41.9-1.0-0.61.8-0.80.11.4-1.3
Mg content in liver0.90.94.51.4-0.11.00.0-0.40.31.30.60.72.10.51.60.4-0.2
Mn content in liver2.42.84.01.5-1.81.6-1.9-1.91.91.7-1.9-1.40.4-1.6-1.22.0-1.8
Na content in liver1.31.42.90.8-1.20.6-1.4-1.11.20.8-1.7-1.2-0.2-1.3-1.61.2-1.2
Rb content in liver1.72.14.7-0.71.6-0.81.71.4-1.4-0.72.01.70.61.82.2-1.41.5
Se content in liver0.10.10.20.00.20.1-0.1-0.20.10.3-0.10.5-0.10.40.50.20.1
Sr content in liver3.22.94.30.8-2.01.3-2.1-1.71.81.0-2.0-2.1-0.6-2.0-2.01.7-1.9
Zn content in liver1.11.21.81.3-1.11.3-1.2-1.21.21.3-0.6-0.81.0-0.8-0.61.2-1.2