Hub : Genes

Mfsd6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000012663 0.03 0.02 6.0e-03 0.01 0.01 0.01 0.01 2.0e-02 1.7e-02 5.6e-02 5.8e-02
2 Brain alternative polyA ENSRNOT00000031267 0.03 0.02 6.1e-04 0.03 0.03 0.03 0.03 7.2e-04 1.2e-03 1.2e-03 1.0e-03
3 Brain gene expression ENSRNOG00000012663 0.46 0.15 0.0e+00 0.25 0.25 0.26 0.25 1.8e-23 8.1e-23 4.7e-24 3.7e-23
4 Brain intron excision ratio chr9:48773600:48793273 0.1 0.07 3.7e-09 0.09 0.09 0.08 0.09 4.9e-09 1.2e-08 6.3e-08 7.1e-09
5 Brain intron excision ratio chr9:48773902:48793273 0.11 0.08 1.3e-09 0.11 0.1 0.1 0.1 5.1e-10 4.2e-09 2.8e-09 2.6e-09
6 Brain mRNA stability ENSRNOG00000012663 0.04 0.03 2.3e-03 0.02 0.03 0.03 0.03 1.2e-02 1.2e-03 1.2e-03 1.9e-03
7 IL gene expression ENSRNOG00000012663 0.31 0.16 2.3e-03 0.02 0.03 0.03 0.03 9.1e-02 6.7e-02 7.8e-02 5.2e-02
8 Liver intron excision ratio chr9:48773600:48793273 0.44 0.2 1.8e-05 0.02 0.01 0.02 0.02 3.4e-03 1.5e-02 1.3e-03 1.3e-03
9 Liver intron excision ratio chr9:48773902:48793273 0.54 0.16 4.1e-09 0.05 0.04 0.04 0.05 2.4e-06 7.1e-05 4.6e-05 6.1e-06
10 NAcc intron excision ratio chr9:48773600:48793273 0.06 0.04 6.3e-05 0.03 0.03 -0 0.03 5.4e-03 1.7e-03 4.3e-01 1.8e-03
11 NAcc intron excision ratio chr9:48773902:48793273 0.06 0.04 7.9e-05 0.02 0.03 0 0.03 6.4e-03 2.1e-03 1.4e-01 2.4e-03
12 PL gene expression ENSRNOG00000012663 0.05 0.04 5.7e-03 0.01 0 -0 0 3.9e-02 1.4e-01 6.3e-01 1.4e-01
13 PL intron excision ratio chr9:48773600:48793273 0.43 0.19 2.6e-06 0.01 0.08 0.09 0.08 7.4e-02 1.5e-06 1.6e-07 5.6e-07
14 PL intron excision ratio chr9:48773902:48793273 0.43 0.19 1.5e-06 0.01 0.08 0.1 0.09 5.5e-02 7.4e-07 6.2e-08 3.6e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail4.715.421.0-4.44.63.6-4.64.6-3.90.8-4.64.6-4.54.52.7-2.82.6
BMI without tail1.22.63.7-1.91.91.2-1.91.9-1.9-0.4-1.91.9-1.71.70.9-1.21.1
Body weight0.10.62.8-0.30.31.3-0.20.20.10.8-0.20.2-0.20.21.71.1-1.2
Epididymis fat weight0.61.33.11.0-0.90.41.1-1.11.20.61.1-1.11.0-1.00.91.7-1.8
Glucose0.61.02.7-1.21.00.3-1.01.0-1.6-1.4-1.01.0-0.90.8-0.0-0.70.7
Heart weight0.40.50.80.9-0.7-0.80.9-0.90.90.30.9-0.90.7-0.7-0.70.2-0.2
Left kidney weight0.10.30.90.2-0.10.60.1-0.10.60.90.1-0.10.1-0.11.00.7-0.7
Right kidney weight0.30.94.0-0.30.61.5-0.50.50.52.0-0.50.5-0.60.61.80.4-0.5
Tail length3.510.613.93.6-3.7-2.03.7-3.73.3-0.23.7-3.73.7-3.7-0.93.5-3.3
Length with tail3.813.918.04.2-4.2-1.84.2-4.24.20.84.2-4.24.1-4.1-0.54.1-4.0
Length without tail0.71.44.71.0-0.80.80.8-0.81.72.20.8-0.80.6-0.61.21.6-1.7
Liver weight, left0.40.65.20.6-0.20.30.3-0.31.32.30.4-0.4-0.00.10.1-0.20.2
Liver weight, right0.30.42.00.5-0.40.50.5-0.50.91.40.5-0.50.2-0.20.60.7-0.7
Parametrial fat weight0.10.20.5-0.40.10.6-0.20.2-0.3-0.1-0.20.2-0.20.20.70.7-0.7
Retroperitoneal fat weight0.20.72.7-0.10.11.3-0.20.20.41.3-0.20.2-0.30.31.61.2-1.3
Intraocular pressure0.20.30.8-0.70.70.4-0.60.6-0.9-0.7-0.60.6-0.50.50.3-0.40.4
Extensor digitorum longus weight3.915.831.9-3.64.15.6-4.14.1-1.44.9-4.14.1-4.44.55.2-0.40.0
Soleus weight0.41.15.6-0.40.81.5-0.80.80.52.4-0.70.7-1.01.01.4-0.30.1
Tibialis anterior weight2.48.211.6-2.93.23.4-3.23.2-1.82.5-3.23.2-3.43.42.7-1.51.3
Tibia length3.810.719.14.0-3.8-2.03.8-3.84.41.83.8-3.83.5-3.5-1.22.2-2.2
Number of licking bursts0.50.63.0-0.70.3-0.5-0.50.5-1.3-1.7-0.50.5-0.30.3-0.7-0.70.7
Food consumed during 24 hour testing period0.50.61.61.0-0.8-0.30.8-0.81.31.10.8-0.80.6-0.6-0.30.5-0.5
Times rat made contact with spout0.60.63.5-0.50.3-0.9-0.20.2-1.1-1.9-0.20.2-0.10.1-1.1-0.80.9
Mean time between licks in bursts1.21.73.6-1.01.21.4-1.41.4-0.31.9-1.41.4-1.51.51.1-1.21.0
Mean num. licks in bursts0.00.00.40.10.10.10.1-0.10.30.60.1-0.1-0.00.00.1-0.10.1
Std. dev. time between licks in bursts4.85.88.0-2.72.72.3-2.82.8-2.20.7-2.82.8-2.82.81.7-1.71.5
Water consumed over 24 hours0.70.81.2-1.11.10.6-1.01.0-1.1-0.2-1.01.0-1.01.00.3-0.80.7
Indifference point 0 sec4.16.715.1-2.32.61.1-2.82.8-2.00.9-2.82.8-2.72.70.1-3.93.8
Indifference point AUC0.70.83.6-0.10.40.0-0.40.40.21.4-0.40.4-0.60.6-0.4-1.91.9
Indifference point function ln k0.91.23.1-1.31.10.3-1.21.2-1.7-1.6-1.21.2-0.90.90.2-0.70.7
Indifference point function log k0.91.23.1-1.31.10.3-1.21.2-1.7-1.6-1.21.2-0.90.90.2-0.70.7
Delay discounting total patch changes 0 sec4.26.816.9-2.32.60.9-2.72.7-2.00.9-2.72.7-2.72.7-0.1-4.14.0
Delay discounting total patch changes 12 sec1.01.35.7-0.50.80.2-0.90.9-0.31.1-0.90.9-1.01.0-0.2-2.42.3
Delay discounting total patch changes 18 sec2.33.09.7-1.31.50.4-1.61.6-1.10.9-1.61.6-1.71.7-0.4-3.13.1
Delay discounting total patch changes 24 sec1.62.17.8-0.91.10.1-1.31.3-0.70.8-1.31.3-1.31.3-0.6-2.82.7
Delay discounting total patch changes 6 sec3.65.414.1-2.02.20.9-2.42.4-1.61.1-2.42.4-2.52.5-0.0-3.73.7
Delay discounting time to switch 0 sec0.91.42.61.0-1.3-0.71.2-1.20.8-0.71.2-1.21.3-1.3-0.31.6-1.5
Delay discounting water rate 0 sec0.81.22.1-1.21.51.0-1.21.2-0.80.6-1.21.2-1.31.30.8-1.00.9
Delay discounting water rate 12 sec0.40.61.2-0.90.80.2-0.80.8-1.1-0.8-0.80.8-0.70.70.1-0.70.7
Delay discounting water rate 18 sec0.20.21.6-0.40.2-0.0-0.20.2-0.8-1.3-0.20.2-0.0-0.00.10.4-0.4
Delay discounting water rate 24 sec0.20.31.3-0.00.00.70.1-0.10.10.10.1-0.10.1-0.11.01.1-1.1
Delay discounting water rate 6 sec1.11.63.0-1.41.40.4-1.51.5-1.7-1.1-1.51.5-1.21.20.1-1.11.1
Locomotor activity0.10.10.5-0.10.10.1-0.40.4-0.10.2-0.40.4-0.20.2-0.0-0.70.7
Locomotor testing distance0.30.62.20.1-0.2-1.0-0.10.1-0.3-0.8-0.10.10.1-0.1-1.4-1.41.5
Locomotor testing rearing0.50.82.1-1.00.70.1-1.01.0-1.4-1.4-1.01.0-0.60.6-0.1-0.80.8
Light reinforcement 13.36.08.6-2.42.72.8-2.82.8-1.52.3-2.82.8-2.92.92.2-1.41.2
Light reinforcement 20.60.71.2-0.81.00.7-1.01.0-0.41.0-1.01.0-1.11.10.3-0.60.6
Reaction time number correct1.31.82.6-1.51.61.6-1.51.5-1.10.6-1.51.5-1.51.51.4-0.60.5
Reaction time mean minus median2.43.14.81.9-1.9-2.21.9-1.91.6-0.71.9-1.91.9-2.0-2.10.8-0.7
Reaction time mean minus median AUC1.72.23.21.5-1.6-1.81.6-1.61.2-0.91.6-1.61.7-1.7-1.71.1-1.0
Reaction time num false alarms3.04.28.3-2.12.12.9-2.12.1-1.31.6-2.12.1-2.32.32.80.0-0.2
Reaction time num false alarms AUC3.04.27.8-2.12.12.8-2.22.2-1.12.0-2.22.2-2.42.42.6-0.30.1
Reaction time trials correct on left1.31.82.6-1.51.61.6-1.51.5-1.10.6-1.51.5-1.51.51.4-0.60.5
Reaction time trials on left1.21.72.4-1.41.61.5-1.51.5-1.00.6-1.51.5-1.51.51.4-0.50.4
Reaction time mean6.99.512.93.2-3.5-2.53.4-3.42.6-1.43.4-3.43.6-3.6-1.73.3-3.1
Reaction time mean AUC6.18.211.12.9-3.2-2.43.1-3.12.3-1.53.1-3.13.3-3.3-1.63.2-3.0
Median of all reaction times6.89.213.63.0-3.4-2.13.3-3.32.4-1.53.3-3.33.5-3.5-1.23.7-3.5
Reaction time omissions0.40.61.50.4-0.6-0.50.7-0.7-0.1-1.20.7-0.70.8-0.8-0.31.1-1.1
Reaction time false alarm rate1.11.53.1-1.21.11.8-1.31.3-0.61.4-1.31.3-1.41.51.6-0.0-0.1
Reaction time premature initiation rate0.00.00.20.0-0.1-0.1-0.00.0-0.1-0.3-0.00.00.1-0.1-0.1-0.40.4
Reaction time premature initiations0.30.50.6-0.70.80.7-0.80.8-0.7-0.1-0.80.8-0.70.70.7-0.60.5
Std. dev. reaction times5.98.110.63.1-3.2-3.13.2-3.22.5-1.13.2-3.23.3-3.3-2.62.0-1.8
Reaction time trials completed1.21.72.4-1.41.61.5-1.51.5-1.00.6-1.51.5-1.51.51.4-0.50.4
Reaction time trials AUC1.21.62.4-1.41.51.5-1.51.5-1.10.5-1.51.5-1.41.41.3-0.50.4
Social response proportion0.80.91.80.8-0.9-0.41.1-1.10.7-0.41.1-1.11.0-1.0-0.01.3-1.3
Social responses0.10.20.7-0.00.20.60.1-0.10.20.20.1-0.1-0.00.00.80.8-0.8
Social time0.60.72.00.6-0.7-1.10.9-0.90.1-1.40.9-0.90.9-1.0-0.90.6-0.5
Conditioned locomotion0.20.21.00.0-0.20.40.1-0.1-0.0-0.30.1-0.10.2-0.20.81.0-1.0
Cocaine response after cond. corrected0.70.82.40.2-0.11.30.0-0.00.81.50.0-0.0-0.00.01.61.4-1.5
Cocaine response after cond. not corrected1.61.84.51.2-1.00.70.9-0.91.81.80.9-0.90.9-0.91.22.0-2.1
Cocaine response before conditioning0.81.01.91.3-1.2-0.81.1-1.11.40.51.1-1.11.1-1.1-0.50.6-0.6
Saline control response0.30.41.3-0.40.3-0.6-0.40.4-0.8-1.0-0.40.4-0.30.3-0.8-1.11.1
Condit. Reinf. active minus inactive responses3.34.15.72.3-2.3-1.42.4-2.42.1-0.22.4-2.42.4-2.4-0.91.8-1.7
Condit. Reinf. active-inactive response ratio2.72.84.21.9-1.9-1.71.9-1.91.4-0.81.9-1.92.0-2.0-1.31.0-0.9
Condit. Reinf. active responses1.01.41.91.3-1.3-0.41.4-1.41.30.41.4-1.41.3-1.30.01.2-1.2
Condit. Reinf. inactive responses0.10.10.90.00.10.60.1-0.10.40.90.1-0.1-0.20.20.60.2-0.3
Condit. Reinf. lever presses0.10.10.20.4-0.3-0.30.3-0.30.50.30.3-0.30.3-0.3-0.4-0.20.2
Condit. Reinf. lever reinforcers received0.91.32.01.2-1.2-0.21.3-1.31.40.61.3-1.31.2-1.20.21.3-1.3
Pavlov. Cond. lever latency0.20.30.6-0.70.70.8-0.50.5-0.7-0.2-0.50.5-0.60.60.70.2-0.3
Pavlov. Cond. magazine entry latency0.30.30.70.8-0.7-0.60.6-0.60.80.30.6-0.60.6-0.6-0.6-0.00.0
Pavlov. Cond. change in total contacts0.91.32.11.4-1.3-1.51.2-1.21.2-0.01.2-1.21.3-1.3-1.4-0.00.1
Pavlov. Cond. index score0.60.81.51.2-1.0-1.01.0-1.01.20.51.0-1.01.0-1.0-0.9-0.10.2
Pavlov. Cond. latency score0.70.81.61.2-1.0-0.90.9-0.91.30.60.9-0.91.0-1.0-0.8-0.00.1
Pavlov. Cond. lever contacts0.50.81.51.0-0.9-1.20.8-0.80.90.10.8-0.80.9-0.9-1.2-0.50.5
Pavlov. Cond. magazine entry number0.80.91.6-1.21.01.3-1.01.0-1.0-0.0-1.01.0-1.01.01.30.2-0.3
Pavlov. Cond. intertrial magazine entries0.70.91.5-1.21.11.1-1.01.0-1.1-0.0-1.01.0-1.11.11.0-0.20.2
Pavlov. Cond. lever-magazine prob. diff.0.40.51.11.0-0.8-0.70.7-0.71.00.60.7-0.70.7-0.7-0.7-0.30.3
Pavlov. Cond. response bias1.01.42.31.5-1.3-1.41.2-1.21.50.51.2-1.21.2-1.2-1.4-0.30.3
Conditioned reinforcement - actives0.40.40.70.6-0.8-0.40.8-0.80.60.00.8-0.80.7-0.7-0.10.6-0.5
Conditioned reinforcement - inactives1.01.11.61.2-1.2-0.81.2-1.21.20.11.3-1.31.2-1.2-0.50.8-0.7
Conditioned locomotion1.41.74.8-1.11.31.5-1.21.2-0.32.2-1.21.2-1.61.61.2-0.60.5
Intermittent access intake day 1-15 change0.70.71.1-0.90.90.6-1.01.0-1.0-0.3-0.90.9-0.80.80.3-0.80.7
Intermittent access intake escalation0.20.20.6-0.60.50.5-0.60.6-0.7-0.5-0.50.5-0.40.40.5-0.10.1
Intermittent access intake escalation 20.10.10.8-0.30.20.1-0.20.2-0.6-0.9-0.20.2-0.00.0-0.0-0.00.0
Intermitt. access day 1 inactive lever presses0.20.20.4-0.40.4-0.2-0.40.4-0.30.1-0.40.4-0.50.5-0.4-0.60.6
Intermitt. access day 15 inactive lever presses0.70.81.10.8-1.1-0.91.0-1.00.7-0.51.1-1.11.0-1.0-0.70.8-0.7
Intermitt. access escalation Index0.90.81.6-1.10.91.1-0.90.9-1.1-0.5-0.90.9-0.80.81.30.5-0.6
Intermittent access day 1 total infusions0.50.51.50.6-0.6-0.90.7-0.70.1-1.20.7-0.70.9-0.9-0.8-0.00.1
Intermittent access day 15 total infusions0.20.31.9-0.40.3-0.1-0.30.3-0.9-1.4-0.30.30.0-0.0-0.2-0.40.4
Intermittent access terminal intake (last 3 days)0.40.41.3-0.60.6-0.1-0.60.6-1.1-1.1-0.60.6-0.30.3-0.3-0.80.8
Intermittent access total infusions0.30.31.50.2-0.2-0.70.3-0.3-0.3-1.20.3-0.30.5-0.5-0.7-0.50.5
Intermittent access day 1 locomotion0.00.00.20.2-0.1-0.40.2-0.20.1-0.20.2-0.20.2-0.2-0.4-0.10.1
Intermittent access day 15 total locomotion0.00.00.00.10.00.10.0-0.00.20.10.1-0.10.1-0.10.10.2-0.2
Intermittent access total locomotion0.10.10.2-0.40.50.1-0.40.4-0.5-0.4-0.40.4-0.30.3-0.1-0.40.3
Intermittent access standard deviation0.30.31.0-0.40.60.1-0.60.6-0.4-0.0-0.60.6-0.40.40.0-1.01.0
Cocaine induced anxiety3.33.88.0-2.02.12.8-2.12.1-1.31.5-2.12.1-2.12.12.70.1-0.3
Post-drug Anxiety1.82.05.2-1.51.42.2-1.41.4-1.10.6-1.41.4-1.41.42.30.3-0.4
Baseline Anxiety2.22.33.91.5-1.7-2.01.7-1.70.8-1.61.7-1.71.8-1.8-1.60.4-0.3
Lifetime Intake0.10.10.50.00.1-0.30.0-0.0-0.3-0.70.1-0.10.2-0.2-0.3-0.40.5
Incentive Sensitization - Responses0.40.40.60.6-0.7-0.20.7-0.70.4-0.40.7-0.70.7-0.70.10.6-0.6
Incentive Sensitization - Breakpoint0.20.20.30.4-0.5-0.10.5-0.50.3-0.40.5-0.50.6-0.60.20.5-0.5
Progressive ratio test 1 active lever presses0.10.10.1-0.10.30.4-0.30.3-0.10.3-0.30.3-0.20.20.3-0.30.2
Progressive ratio test 1 breakpoint0.10.10.2-0.20.40.3-0.30.3-0.00.5-0.30.3-0.20.30.1-0.50.4
Progressive ratio test 1 inactive lever presses0.00.00.30.00.10.2-0.10.10.20.5-0.00.0-0.10.10.20.1-0.1
Progressive ratio test 2 active lever presses0.10.20.40.3-0.3-0.10.4-0.40.1-0.60.4-0.40.6-0.60.10.4-0.4
Progressive ratio test 2 breakpoint0.10.10.7-0.10.1-0.0-0.00.0-0.4-0.80.0-0.00.2-0.20.10.1-0.1
Progressive ratio test 2 inactive lever presses0.20.20.30.4-0.5-0.30.5-0.50.2-0.30.5-0.50.5-0.5-0.20.3-0.3
Total sessions with >9 infusions0.70.83.9-0.30.71.5-0.60.60.32.0-0.50.5-0.80.81.3-0.0-0.1
Short access day 1 total inactive lever presses0.10.11.0-0.10.20.2-0.20.20.31.0-0.20.2-0.30.30.1-0.20.1
Short access day 10 total inactive lever presses0.50.50.70.8-0.9-0.40.8-0.80.80.30.8-0.80.8-0.8-0.20.7-0.7
Short access day 1 total infusions0.20.21.00.20.1-0.2-0.00.00.41.00.0-0.0-0.20.2-0.5-1.01.0
Short access day 10 total infusions0.30.32.9-0.20.2-0.4-0.00.0-0.9-1.7-0.00.00.2-0.2-0.3-0.20.2
Short access total infusions0.10.10.2-0.20.40.2-0.30.3-0.30.0-0.30.3-0.30.30.1-0.40.4
Short access day 1 locomotion0.20.21.60.00.30.2-0.20.20.41.3-0.20.2-0.30.3-0.0-0.10.1
Short access day 10 total locomotion0.20.20.60.5-0.50.20.5-0.50.80.70.5-0.50.4-0.40.30.5-0.5
Short access total locomotion0.40.43.2-0.10.30.9-0.20.20.61.8-0.20.2-0.50.50.80.3-0.3
Compulsive drug intake0.10.10.3-0.50.20.4-0.30.3-0.5-0.4-0.30.3-0.30.30.50.3-0.3
One hour access (0.3 mA shock)0.20.31.90.2-0.4-0.50.4-0.4-0.3-1.40.4-0.40.6-0.6-0.20.3-0.3
One hour access (shock baseline)0.30.31.00.4-0.4-0.70.5-0.50.0-1.00.5-0.50.7-0.7-0.60.2-0.1
Number of responses in last shaping day0.20.20.3-0.40.60.5-0.50.5-0.30.2-0.50.5-0.40.40.3-0.20.2
Context. condit. distance diff. score1.41.74.8-1.61.30.5-1.31.3-2.2-2.0-1.31.3-1.11.00.3-0.70.7
Locomotion velocity, session 10.10.10.3-0.30.20.4-0.20.2-0.4-0.4-0.20.2-0.10.10.60.4-0.5
Locomotion distance, session 10.20.30.8-0.50.50.8-0.50.5-0.30.5-0.50.5-0.60.60.9-0.1-0.0
Locomotion velocity, session 21.41.62.6-1.21.41.6-1.41.4-0.71.3-1.41.4-1.51.51.4-0.50.4
Locomotion distance, session 20.50.81.7-0.70.91.2-0.90.9-0.21.3-0.90.9-1.01.01.1-0.30.2
Locomotion velocity, session 30.10.20.3-0.50.50.3-0.50.5-0.5-0.1-0.50.5-0.50.50.2-0.20.2
Locomotion distance, session 30.50.51.1-0.80.7-0.1-0.80.8-1.0-0.7-0.80.8-0.70.7-0.4-0.80.8
Stereotopy head waving bouts, day 30.40.50.9-0.80.81.0-0.80.8-0.50.5-0.80.8-0.80.80.9-0.20.1
Stereotopy head waving duration, day 30.10.10.4-0.30.20.5-0.20.2-0.2-0.0-0.20.2-0.20.20.70.2-0.3
Locomotion velocity, session 70.50.53.1-0.00.21.0-0.20.20.61.8-0.20.2-0.40.41.20.5-0.6
Locomotion distance, session 70.60.72.2-0.30.31.3-0.30.30.41.5-0.30.3-0.50.51.51.1-1.2
Stereotopy head waving bouts, day 70.20.20.40.3-0.4-0.30.4-0.40.1-0.60.4-0.40.5-0.5-0.20.5-0.5
Stereotopy head waving duration, day 70.50.61.00.9-0.9-0.80.9-0.90.6-0.50.9-0.91.0-1.0-0.70.5-0.5
Locomotion velocity, session 80.50.61.1-0.70.7-0.0-0.70.7-1.0-0.6-0.70.7-0.60.6-0.4-1.01.0
Locomotion distance, session 81.31.93.0-1.71.60.8-1.61.6-1.7-0.6-1.61.6-1.51.50.5-1.21.1
Degree of sensitization distance1.11.13.10.7-0.60.90.6-0.61.31.80.6-0.60.4-0.41.41.6-1.7
Degree of sensitization stereotypy0.30.30.80.4-0.5-0.80.5-0.50.0-0.90.5-0.50.5-0.5-0.9-0.10.2
Condit. Reinf. active minus inactive responses4.34.86.82.2-2.5-1.32.4-2.41.8-1.02.4-2.42.6-2.6-0.32.6-2.5
Condit. Reinf. active-inactive response ratio2.62.84.91.6-1.8-0.81.8-1.81.3-0.91.8-1.81.9-1.9-0.12.2-2.1
Condit. Reinf. active responses3.84.67.12.2-2.4-0.92.4-2.42.1-0.32.4-2.42.5-2.50.12.7-2.6
Condit. Reinf. inactive responses0.30.41.10.3-0.40.60.4-0.40.70.80.4-0.40.3-0.31.01.0-1.0
Incentive salience index mean3.03.65.42.0-2.2-1.62.2-2.21.4-1.32.2-2.22.3-2.3-0.91.7-1.6
Condit. Reinf. lever presses0.60.82.20.6-0.9-1.10.9-0.90.1-1.50.9-0.91.0-1.0-0.70.6-0.5
Time in familiar zone, hab. session 10.50.51.0-0.90.80.6-0.80.8-1.0-0.7-0.80.8-0.60.60.5-0.20.2
Time in novel zone, hab. session 13.23.14.31.9-2.0-2.12.0-2.01.4-1.02.0-2.02.1-2.1-1.80.8-0.7
Total zone transitions, hab. session 10.30.41.90.7-0.50.10.5-0.51.11.40.5-0.50.3-0.30.30.5-0.4
Total locomotion distance, hab. session 11.42.05.21.6-1.30.11.4-1.42.32.31.4-1.41.1-1.00.61.3-1.3
Locomotion velocity, hab. session 10.60.96.10.8-0.50.60.6-0.61.62.50.6-0.60.2-0.20.90.5-0.6
Time in familiar zone, hab. session 20.00.00.3-0.10.0-0.3-0.00.0-0.3-0.6-0.00.00.0-0.1-0.3-0.00.1
Time in novel zone, hab. session 20.00.00.3-0.20.1-0.0-0.10.1-0.3-0.6-0.10.1-0.00.00.0-0.10.1
Total zone transitions, hab. session 20.00.00.1-0.20.2-0.0-0.20.2-0.4-0.4-0.20.2-0.20.10.0-0.20.2
Total locomotion distance, hab. session 20.50.61.10.8-0.80.20.8-0.81.00.70.8-0.80.7-0.70.71.0-1.0
Locomotion velocity, hab. session 20.40.61.10.7-0.70.40.7-0.71.11.00.7-0.70.6-0.50.81.0-1.0
Novel to familiar place preference ratio1.31.32.01.3-1.3-1.41.3-1.30.9-0.71.3-1.31.3-1.3-1.30.2-0.1
Novelty place preference0.91.01.90.9-1.0-1.41.0-1.00.5-1.01.0-1.01.1-1.1-1.3-0.10.2
Time in novel zone, NPP test1.11.12.21.0-1.1-1.51.1-1.10.5-1.11.1-1.11.2-1.2-1.4-0.00.1
Total zone transitions, NPP test0.40.61.7-0.80.71.2-0.70.7-0.60.3-0.70.7-0.70.71.30.5-0.6
Total locomotion distance, NPP test0.20.31.00.6-0.5-0.10.5-0.50.91.00.5-0.50.3-0.30.10.1-0.1
Locomotion velocity, NPP test0.10.21.40.2-0.10.20.0-0.00.61.20.0-0.0-0.10.10.2-0.30.3
Pavlov. Cond. lever latency1.92.43.5-1.51.71.9-1.71.7-0.81.7-1.71.7-1.81.81.5-0.80.7
Pavlov. Cond. magazine entry latency2.22.94.11.8-1.9-1.51.9-1.91.3-1.11.9-1.92.0-2.0-1.01.6-1.5
Pavlov. Cond. change in total contacts1.51.62.41.2-1.4-1.01.4-1.40.7-1.31.4-1.41.5-1.6-0.51.3-1.3
Pavlov. Cond. index score1.82.33.81.4-1.6-1.91.6-1.60.6-2.01.6-1.61.8-1.8-1.60.7-0.6
Pavlov. Cond. latency score2.02.53.71.5-1.7-1.91.7-1.70.7-1.81.7-1.71.9-1.9-1.50.9-0.7
Pavlov. Cond. lever contacts0.91.13.90.7-0.9-1.60.9-0.9-0.1-2.00.9-0.91.1-1.1-1.4-0.10.1
Pavlov. Cond. magazine entry number3.54.36.4-2.12.32.1-2.32.3-1.41.8-2.32.3-2.52.51.5-1.61.5
Pavlov. Cond. intertrial magazine entries0.20.21.0-0.20.20.8-0.20.2-0.00.3-0.20.2-0.10.21.00.6-0.7
Pavlov. Cond. lever-magazine prob. diff.1.51.82.91.2-1.4-1.71.4-1.40.5-1.71.4-1.41.6-1.6-1.30.7-0.6
Pavlov. Cond. response bias1.62.03.71.2-1.5-1.71.5-1.50.5-1.91.5-1.51.6-1.7-1.40.7-0.6
Bone: apparent density2.23.67.72.0-2.0-2.82.0-2.01.3-1.12.0-2.02.0-2.0-2.7-0.60.7
Bone surface0.71.32.31.4-1.3-1.21.2-1.21.50.91.2-1.21.0-1.0-1.2-0.20.3
Bone volume1.93.24.72.1-2.1-2.22.0-2.01.90.02.0-2.01.9-1.9-2.00.00.1
Bone: connectivity density0.40.72.30.7-0.6-1.30.6-0.60.4-0.30.6-0.60.6-0.6-1.5-0.91.0
Bone: cortical apparent density5.47.09.8-2.93.03.1-3.03.0-2.21.4-3.03.0-3.13.12.7-0.70.5
Bone: cortical area0.30.42.50.3-0.20.80.1-0.10.81.60.1-0.1-0.00.01.00.5-0.6
Bone: cortical porosity1.61.74.41.3-1.2-2.01.3-1.30.9-0.71.3-1.31.3-1.3-2.1-0.50.6
Bone: cortical porosity2.02.24.61.7-1.5-2.11.6-1.61.3-0.41.6-1.61.5-1.5-2.1-0.40.6
Bone: cortical thickness1.11.82.6-1.51.51.6-1.51.5-1.10.8-1.51.5-1.61.61.4-0.70.6
Bone: cortical thickness0.10.10.40.3-0.20.10.2-0.20.40.60.2-0.20.1-0.10.10.1-0.1
Bone: cortical tissue density5.36.99.7-2.92.93.1-3.03.0-2.21.4-3.03.0-3.13.12.7-0.60.5
Bone: elastic displacement0.50.62.8-0.1-0.0-1.10.0-0.0-0.8-1.70.0-0.00.2-0.2-1.4-0.80.9
Bone: elastic work1.31.72.31.5-1.5-1.41.5-1.51.3-0.31.5-1.51.5-1.5-1.20.7-0.6
Bone: endosteal estimation3.37.112.73.3-3.1-1.73.1-3.13.61.43.1-3.12.9-2.9-1.11.7-1.6
Bone: endosteal perimeter1.53.15.32.1-2.0-0.62.0-2.02.31.02.0-2.01.9-1.90.01.7-1.7
Bone: final force1.01.64.11.4-1.20.21.2-1.22.02.01.2-1.21.0-0.90.61.2-1.3
Bone: final moment0.60.93.51.0-0.90.30.8-0.81.61.90.8-0.80.6-0.60.60.8-0.8
Bone: marrow area3.16.612.03.2-3.0-1.63.0-3.03.51.43.0-3.02.8-2.8-1.11.7-1.6
Bone: maximum diameter0.10.20.70.2-0.20.50.1-0.10.50.80.1-0.10.1-0.10.70.4-0.5
Bone: maximum force1.93.48.32.3-2.0-0.52.0-2.02.92.32.0-2.01.7-1.7-0.11.3-1.3
Bone: maximum moment1.22.25.91.8-1.6-0.41.5-1.52.42.11.5-1.51.3-1.2-0.20.8-0.8
Bone: minimum diameter0.61.23.61.3-1.1-0.01.0-1.01.91.91.0-1.00.8-0.80.20.5-0.6
Bone: periosteal estimation1.83.87.92.4-2.2-0.82.2-2.22.81.72.2-2.22.0-2.0-0.41.3-1.3
Bone: periosteal perimeter0.81.42.51.4-1.4-0.31.3-1.31.60.81.3-1.31.2-1.20.21.1-1.1
Bone: post-yield work1.31.73.51.6-1.5-0.61.5-1.51.91.11.5-1.51.3-1.3-0.21.1-1.1
Bone: stiffness1.82.87.01.9-1.70.11.7-1.72.62.41.7-1.71.4-1.40.51.6-1.6
Bone: tissue strength0.00.00.20.1-0.0-0.0-0.00.00.20.5-0.00.0-0.10.1-0.1-0.10.1
Bone: trabecular number1.11.72.91.5-1.5-1.71.4-1.41.1-0.31.4-1.41.4-1.4-1.6-0.20.3
Bone: trabecular spacing0.70.93.4-0.50.51.6-0.40.4-0.00.9-0.40.4-0.50.51.81.4-1.5
Bone: trabecular thickness3.13.78.31.9-2.0-2.92.0-2.01.0-1.72.0-2.02.0-2.0-2.8-0.40.6
Bone: trabecular tissue density0.50.62.30.5-0.60.50.6-0.60.80.50.6-0.60.5-0.50.91.5-1.5
Breakpoint value in progressive ratio session0.91.02.40.8-1.0-0.21.1-1.10.6-0.61.1-1.11.1-1.10.21.5-1.5
Distance traveled before self-admin5.25.68.32.8-2.8-2.12.8-2.82.90.72.9-2.92.5-2.5-1.41.1-1.0
Distance traveled after self-admin1.31.42.11.3-1.4-0.51.4-1.41.50.41.4-1.41.2-1.2-0.11.2-1.2
Delta time in closed arm before/after self-admin0.80.81.1-0.81.01.0-1.01.0-0.41.0-1.01.0-1.01.00.7-0.70.7
Delta time in open arm before/after self-admin3.43.25.31.9-2.0-2.32.1-2.11.4-1.02.0-2.02.0-2.0-2.10.5-0.3
Diff in mean of infusions in LGA sessions1.31.52.21.2-1.4-1.01.4-1.40.8-0.91.4-1.41.5-1.5-0.90.9-0.9
Extinction: sum of active levers before priming1.61.62.61.3-1.4-0.61.4-1.41.1-0.21.4-1.41.4-1.4-0.11.6-1.6
Active lever presses in extinction session 60.50.51.30.4-0.7-0.60.7-0.70.1-1.10.7-0.70.8-0.8-0.40.7-0.7
Delta distance traveled before/after self-admin0.91.01.9-1.21.01.4-1.01.0-1.0-0.1-1.01.0-1.01.01.20.4-0.5
Delta ambulatory time before/after self-admin1.11.22.4-1.31.21.5-1.21.2-1.1-0.0-1.21.2-1.11.11.40.4-0.5
Time in closed arm before self-admin2.32.73.71.9-1.9-1.91.9-1.91.5-0.41.9-1.91.8-1.8-1.70.3-0.2
Time in closed arm after self-admin0.20.20.50.6-0.5-0.20.5-0.50.70.60.5-0.50.4-0.4-0.2-0.10.1
Time in open arm before self-admin2.72.87.0-1.81.82.5-1.71.7-1.40.5-1.71.7-1.61.62.60.4-0.6
Time in open arm after self-admin2.22.43.51.7-1.8-1.51.9-1.91.3-0.71.8-1.81.8-1.8-1.01.1-1.0
Sum of active levers in priming session hrs 5-62.42.45.31.4-1.6-0.41.6-1.61.2-0.61.6-1.61.7-1.70.12.3-2.3
Time to tail flick, vehicle, before self-admin0.50.60.8-0.90.90.6-0.90.9-0.9-0.1-0.90.9-0.80.80.3-0.30.3
Time to tail flick, vehicle, after self-admin0.10.20.30.3-0.4-0.10.4-0.40.1-0.50.4-0.40.5-0.50.00.6-0.5
Time to tail flick, test, before self-admin1.21.23.4-1.01.01.8-1.01.0-0.50.9-1.01.0-1.11.11.80.5-0.7
Time to tail flick, test, after self-admin1.61.62.4-1.31.41.4-1.41.4-0.71.3-1.41.4-1.51.51.0-1.00.9
Delta time to tail flick, vehicle, before/after SA0.70.71.11.0-1.0-0.61.0-1.00.9-0.11.0-1.01.0-1.0-0.40.5-0.4
Delta time to tail flick, test, before/after SA0.80.73.4-0.10.3-1.0-0.30.3-0.30.0-0.20.2-0.30.3-1.5-1.81.8
Ambulatory time before self-admin4.14.36.22.4-2.4-1.82.5-2.52.50.52.5-2.52.2-2.2-1.21.3-1.2
Ambulatory time after self-admin0.30.30.60.4-0.50.20.5-0.50.70.70.5-0.50.4-0.30.40.8-0.8
Total heroin consumption0.70.82.20.7-0.9-1.30.9-0.90.3-1.00.9-0.90.9-0.9-1.5-0.10.2
Area under the delay curve0.00.00.2-0.1-0.00.10.0-0.0-0.2-0.40.0-0.00.1-0.10.30.3-0.3
Delay disc. indifference point, 0s delay0.10.10.50.1-0.1-0.60.1-0.1-0.0-0.30.1-0.10.1-0.1-0.6-0.70.7
Delay disc. indifference point, 16s delay0.50.50.70.6-0.8-0.40.8-0.80.4-0.60.8-0.80.8-0.80.00.8-0.8
Delay disc. indifference point, 2s delay0.00.00.20.1-0.0-0.30.0-0.00.10.10.0-0.00.00.0-0.3-0.40.5
Delay disc. indifference point, 24s delay0.20.21.1-0.40.20.2-0.20.2-0.7-1.0-0.20.2-0.10.10.40.5-0.5
Delay disc. indifference point, 4s delay0.30.30.4-0.60.60.5-0.60.6-0.50.1-0.60.6-0.60.60.5-0.50.4
Delay disc. indifference point, 8s delay0.40.41.00.6-0.7-0.10.7-0.70.5-0.20.7-0.70.7-0.70.31.0-1.0
Delay discount exponential model param0.00.00.30.1-0.0-0.00.0-0.00.30.60.0-0.0-0.10.1-0.3-0.20.2
Delay discount hyperbolic model param0.00.00.10.2-0.2-0.20.2-0.20.30.30.2-0.20.1-0.1-0.4-0.10.1
Fecal boli incidents, locomotor time 10.10.10.2-0.20.3-0.2-0.30.3-0.3-0.1-0.30.3-0.30.3-0.5-0.30.4
Change in fecal boli incidents, locomotor task0.10.10.5-0.30.20.1-0.10.1-0.5-0.7-0.10.1-0.10.10.2-0.10.1
Time >=10cm from walls, locomotor time 10.40.42.00.2-0.00.9-0.00.00.71.4-0.00.0-0.10.11.10.4-0.5
Bouts of movement, locomotor time 10.91.01.4-1.21.20.8-1.21.2-1.10.1-1.21.2-1.21.20.4-0.60.6
Total resting periods, locomotor time 11.21.42.1-1.31.41.1-1.41.4-1.10.5-1.41.4-1.41.40.7-0.70.6
Rest time, locomotor task time 10.70.81.4-1.00.90.1-1.01.0-1.1-0.5-0.90.9-0.90.9-0.3-1.21.2
Distance moved, locomotor task time 10.40.51.90.3-0.50.50.4-0.40.3-0.20.4-0.40.5-0.51.11.3-1.4
Vertical activity count, locomotor time 10.10.10.60.1-0.10.40.1-0.10.20.20.1-0.10.1-0.10.80.6-0.7
Time >=10cm from walls, locomotor time 21.11.21.91.1-1.2-1.41.2-1.20.7-1.01.2-1.21.3-1.3-1.10.4-0.3
Bouts of movement, locomotor time 22.83.14.7-2.12.02.2-2.02.0-1.60.5-1.91.9-2.02.02.0-0.30.1
Total resting periods, locomotor time 22.93.04.2-2.12.11.9-2.02.0-1.70.5-1.91.9-2.02.01.7-0.70.6
Rest time, locomotor task time 21.61.95.3-1.31.30.1-1.31.3-1.4-0.3-1.31.3-1.31.3-0.5-2.32.3
Distance moved, locomotor task time 20.91.03.00.9-1.00.11.0-1.00.90.00.9-0.91.0-1.00.81.7-1.7
Vertical activity count, locomotor time 20.20.20.7-0.20.10.6-0.10.1-0.3-0.4-0.20.2-0.00.00.80.8-0.9
Weight adjusted by age0.70.82.80.9-0.80.40.8-0.81.41.70.8-0.80.6-0.50.60.9-0.9
Seeking ratio, delayed vs. immediate footshock2.02.33.31.8-1.8-1.31.8-1.81.7-0.01.8-1.81.8-1.8-0.90.8-0.7
Locomotion in novel chamber1.31.65.9-0.81.11.8-1.11.10.02.4-1.11.1-1.31.31.4-0.50.3
Locomotion in novel chamber post-restriction0.80.93.5-0.60.81.3-0.80.80.21.9-0.80.8-1.01.01.4-0.30.2
Progressive ratio0.50.62.8-0.30.21.4-0.20.20.10.7-0.20.2-0.20.21.71.1-1.2
Food seeking constrained by brief footshock0.40.51.80.1-0.01.00.0-0.00.61.30.0-0.0-0.00.11.11.0-1.1
Seeking ratio, punishment vs. effort0.10.10.40.3-0.2-0.40.1-0.10.40.50.2-0.20.1-0.1-0.6-0.50.5
Run reversals in cocaine runway, females0.40.41.7-0.00.11.0-0.10.10.51.3-0.10.1-0.30.31.20.7-0.7
Run reversals in cocaine runway, males0.90.92.7-0.70.81.5-0.70.7-0.21.3-0.80.8-0.80.81.70.5-0.5
Latency to leave start box in cocaine runway5.05.58.1-2.62.71.9-2.72.7-2.10.9-2.72.7-2.82.81.1-2.01.8
Latency to leave start box in cocaine runway, F3.84.17.4-2.12.20.6-2.22.2-1.90.2-2.22.2-2.32.3-0.3-2.72.7
Latency to leave start box in cocaine runway, M2.22.15.8-1.21.32.3-1.31.3-0.41.7-1.31.3-1.41.42.40.6-0.8
Cd content in liver0.91.02.01.1-1.0-0.01.0-1.01.41.01.0-1.00.9-0.90.41.3-1.3
Co content in liver0.40.42.60.2-0.5-0.70.5-0.5-0.3-1.60.5-0.50.6-0.7-0.60.5-0.4
Cu content in liver1.62.03.11.4-1.6-1.31.6-1.60.9-1.21.5-1.51.8-1.8-0.81.2-1.1
Fe content in liver2.63.14.41.9-2.0-1.82.0-2.01.3-1.12.0-2.02.1-2.1-1.51.3-1.2
K content in liver1.31.33.3-0.71.00.4-1.11.1-0.31.3-1.11.1-1.21.2-0.3-1.81.8
Mg content in liver1.01.02.3-0.91.00.4-1.11.1-0.70.6-1.11.1-1.11.1-0.2-1.51.5
Mn content in liver1.01.14.0-0.80.8-0.5-0.80.8-1.1-0.7-0.80.8-0.80.8-1.2-2.02.0
Na content in liver0.30.31.3-0.20.3-0.3-0.40.4-0.30.2-0.40.4-0.40.4-0.6-1.11.1
Rb content in liver1.11.34.3-0.80.92.0-0.90.9-0.11.6-0.80.8-1.01.02.10.9-1.0
Se content in liver0.10.10.4-0.20.30.0-0.30.3-0.10.4-0.30.3-0.30.3-0.0-0.60.6
Sr content in liver0.20.20.4-0.50.40.5-0.40.4-0.6-0.4-0.40.4-0.30.30.60.1-0.1
Zn content in liver0.60.71.2-0.90.91.1-1.01.0-0.70.4-1.01.0-0.90.91.0-0.30.3