Hub : Genes

Mecom

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000095020 0.06 0.04 4.7e-04 0.01 0.01 0.01 0.01 2.1e-02 5.5e-02 1.8e-02 3.8e-02
2 Adipose alternative polyA ENSRNOT00000107461 0.07 0.04 3.2e-04 0.01 0.01 0.01 0.01 1.4e-02 5.3e-02 2.6e-02 3.4e-02
3 Adipose alternative polyA ENSRNOT00000095020 0.06 0.04 4.2e-04 0.01 0.01 0.01 0.01 2.3e-02 6.0e-02 1.7e-02 4.2e-02
4 Adipose alternative polyA ENSRNOT00000107461 0.07 0.04 3.1e-04 0.01 0.01 0.01 0.01 1.3e-02 5.5e-02 1.7e-02 3.0e-02
5 Adipose alternative TSS ENSRNOT00000095020 0.04 0.03 6.3e-03 0.01 0.01 0.01 0.01 2.0e-02 4.2e-02 8.4e-03 8.7e-03
6 Adipose alternative TSS ENSRNOT00000107461 0.04 0.03 3.4e-03 0.01 0.01 0.01 0.01 1.3e-02 1.6e-02 7.3e-03 8.7e-03
7 Adipose alternative TSS ENSRNOT00000095020 0.04 0.03 3.4e-03 0 0.01 0.02 0.01 1.1e-01 2.5e-02 6.0e-03 7.5e-03
8 Adipose alternative TSS ENSRNOT00000107461 0.04 0.03 3.0e-03 0.01 0.01 0.02 0.01 4.5e-02 2.2e-02 6.3e-03 8.2e-03
9 Adipose gene expression ENSRNOG00000012645 0.08 0.05 7.6e-04 0.01 0.01 0.02 0.02 1.5e-02 2.1e-02 3.0e-03 1.9e-03
10 Adipose isoform ratio ENSRNOT00000095020 0.04 0.03 1.0e-02 0.02 0 0.01 0.01 5.6e-03 1.1e-01 7.0e-02 7.1e-03
11 Adipose mRNA stability ENSRNOG00000012645 0.11 0.06 3.6e-06 0.02 0.04 0.05 0.04 5.6e-03 1.9e-05 4.2e-06 9.3e-06
12 Brain gene expression ENSRNOG00000012645 0.06 0.03 3.6e-04 0.04 0.03 0.02 0.03 2.9e-04 6.1e-04 7.2e-03 1.3e-03
13 Eye alternative TSS ENSRNOT00000107461 0.32 0.15 7.0e-03 0.01 0 -0.02 0.01 2.0e-01 3.1e-01 9.0e-01 2.0e-01
14 LHb alternative TSS ENSRNOT00000068381 0.27 0.14 3.8e-03 0.01 0.1 0.12 0.06 1.6e-01 1.8e-03 8.3e-04 1.6e-02
15 LHb isoform ratio ENSRNOT00000099354 0.31 0.19 5.8e-03 0.04 0.13 0.09 0.05 5.3e-02 6.2e-04 4.9e-03 2.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.92.85.3-0.61.5-0.81.51.8-1.81.8-1.81.31.02.21.7-1.82.0-2.3
BMI without tail0.20.54.10.30.30.30.30.1-0.2-0.10.1-0.7-0.90.00.5-0.30.9-2.0
Body weight0.73.16.2-1.00.9-1.20.92.0-2.02.3-2.21.92.02.51.4-1.61.7-1.4
Epididymis fat weight0.10.20.7-0.60.8-0.70.8-0.10.10.00.0-0.00.40.7-0.50.60.30.0
Glucose1.21.87.2-0.20.2-0.30.2-1.51.6-1.51.6-1.3-0.2-0.3-2.02.7-0.61.7
Heart weight0.40.51.60.6-0.10.5-0.10.7-0.80.6-0.70.40.00.51.2-0.91.2-1.1
Left kidney weight0.10.20.5-0.40.5-0.40.5-0.40.5-0.40.4-0.7-0.70.0-0.40.2-0.20.0
Right kidney weight0.10.30.8-0.60.7-0.60.7-0.20.2-0.20.2-0.4-0.8-0.10.1-0.40.3-0.9
Tail length0.20.51.91.0-1.41.0-1.40.4-0.40.3-0.3-0.10.1-0.10.30.00.5-0.7
Length with tail0.41.54.30.3-1.20.2-1.21.4-1.41.7-1.61.52.11.30.9-0.60.9-0.1
Length without tail1.12.58.2-0.2-0.5-0.3-0.51.8-1.82.2-2.12.32.92.11.1-0.71.00.7
Liver weight, left1.42.29.2-2.92.2-3.02.2-0.70.7-0.60.7-0.30.00.6-1.30.8-0.81.2
Liver weight, right0.81.32.70.3-0.60.4-0.6-1.31.3-1.41.4-1.4-1.4-1.5-1.11.1-1.60.7
Parametrial fat weight0.20.40.70.30.30.30.3-0.70.7-0.80.8-0.8-0.4-0.7-0.60.80.4-0.8
Retroperitoneal fat weight0.20.81.8-0.61.3-0.71.3-1.11.1-1.01.0-1.0-0.6-0.4-1.00.80.0-0.2
Intraocular pressure0.10.10.50.0-0.30.0-0.3-0.20.2-0.10.2-0.10.10.2-0.50.7-0.30.7
Extensor digitorum longus weight0.93.511.00.2-0.1-0.1-0.12.3-2.22.0-2.11.52.22.81.9-0.63.3-2.1
Soleus weight3.08.830.42.7-2.52.7-2.53.0-3.02.3-2.50.8-0.21.14.3-2.34.3-5.5
Tibialis anterior weight0.72.58.90.7-0.30.5-0.31.8-1.81.6-1.60.91.52.11.6-0.53.0-2.4
Tibia length1.74.810.6-0.90.7-0.90.7-2.72.8-2.62.7-1.9-0.9-1.3-3.23.0-2.23.3
Number of licking bursts0.91.13.7-1.61.9-1.61.90.1-0.10.1-0.20.1-0.20.40.2-0.90.6-1.5
Food consumed during 24 hour testing period1.21.43.2-1.30.8-1.40.81.3-1.31.2-1.21.21.21.81.2-0.91.2-0.6
Times rat made contact with spout1.21.35.8-2.31.9-2.41.9-0.20.3-0.10.20.30.30.7-0.40.10.00.7
Mean time between licks in bursts0.50.71.51.2-1.21.1-1.20.5-0.40.3-0.30.41.20.70.10.91.00.8
Mean num. licks in bursts0.20.32.2-0.2-0.6-0.2-0.60.1-0.00.1-0.10.50.60.1-0.10.3-0.31.5
Std. dev. time between licks in bursts0.40.41.1-0.90.8-1.00.80.1-0.00.2-0.10.50.81.1-0.30.4-0.01.1
Water consumed over 24 hours0.50.62.2-1.41.3-1.51.30.3-0.30.3-0.30.30.30.90.2-0.20.5-0.2
Indifference point 0 sec0.20.41.8-0.30.4-0.30.40.6-0.60.4-0.4-0.30.11.10.10.41.0-1.4
Indifference point AUC1.41.64.1-1.62.0-1.52.0-1.00.9-0.80.7-0.7-1.9-1.0-0.5-0.9-1.6-0.2
Indifference point function ln k1.01.54.11.5-1.71.4-1.71.0-0.90.9-0.90.72.01.00.21.11.4-0.1
Indifference point function log k1.01.54.11.5-1.71.4-1.71.0-0.90.9-0.90.72.01.00.21.11.4-0.1
Delay discounting total patch changes 0 sec0.20.41.8-0.40.6-0.40.60.5-0.40.3-0.3-0.4-0.11.00.00.50.8-1.3
Delay discounting total patch changes 12 sec0.91.33.5-1.71.9-1.61.9-0.60.6-0.60.6-0.7-1.6-0.3-0.6-0.4-1.20.0
Delay discounting total patch changes 18 sec0.50.62.0-1.41.3-1.41.30.3-0.40.3-0.30.1-0.50.60.1-0.60.2-0.3
Delay discounting total patch changes 24 sec0.70.92.8-1.21.5-1.11.50.1-0.20.1-0.1-0.2-1.3-0.00.4-1.30.1-1.7
Delay discounting total patch changes 6 sec0.40.73.4-0.70.9-0.50.9-0.50.4-0.60.5-1.1-1.9-0.4-0.3-0.2-0.5-1.3
Delay discounting time to switch 0 sec0.30.51.71.3-1.21.2-1.20.2-0.10.2-0.10.10.50.00.20.30.60.1
Delay discounting water rate 0 sec0.50.82.1-0.70.8-0.60.8-0.90.9-1.01.0-1.2-1.4-0.9-0.80.5-0.7-0.6
Delay discounting water rate 12 sec0.91.32.41.4-1.41.6-1.4-0.90.9-0.90.9-1.4-0.9-1.2-1.11.5-1.00.2
Delay discounting water rate 18 sec0.81.04.0-2.01.5-1.91.5-0.50.4-0.20.30.40.00.0-0.7-0.5-1.10.8
Delay discounting water rate 24 sec0.60.82.2-1.51.2-1.41.2-0.60.5-0.60.6-0.8-1.3-0.6-0.4-0.4-0.4-1.0
Delay discounting water rate 6 sec0.10.20.50.6-0.10.7-0.1-0.40.4-0.50.4-0.6-0.5-0.6-0.20.50.2-0.6
Locomotor activity0.50.84.0-0.1-1.0-0.2-1.00.5-0.50.6-0.61.31.40.60.0-0.0-0.42.0
Locomotor testing distance0.91.54.20.4-1.30.4-1.31.3-1.31.4-1.42.01.81.00.7-1.1-0.31.3
Locomotor testing rearing0.20.42.10.3-0.80.4-0.8-0.20.2-0.20.20.1-0.1-0.2-0.50.3-1.01.4
Light reinforcement 10.50.82.31.2-1.51.2-1.5-0.00.1-0.10.1-0.50.10.3-0.61.4-0.61.5
Light reinforcement 20.10.10.5-0.30.2-0.40.20.00.0-0.00.0-0.2-0.20.7-0.00.40.30.5
Reaction time number correct0.81.12.5-0.4-0.1-0.3-0.1-1.31.3-1.21.3-1.1-0.6-0.6-1.61.5-1.31.0
Reaction time mean minus median4.76.111.50.50.40.30.43.2-3.23.3-3.33.03.33.42.4-1.62.8-1.4
Reaction time mean minus median AUC3.14.06.90.50.40.30.42.5-2.52.6-2.62.42.42.62.1-1.32.4-1.5
Reaction time num false alarms0.40.51.1-0.4-0.0-0.4-0.00.9-0.81.0-0.91.10.70.90.6-0.9-0.20.9
Reaction time num false alarms AUC0.20.21.6-0.2-0.4-0.1-0.40.1-0.10.2-0.20.40.10.1-0.1-0.3-1.01.3
Reaction time trials correct on left0.81.12.5-0.4-0.1-0.3-0.1-1.31.3-1.21.3-1.1-0.6-0.6-1.61.5-1.31.0
Reaction time trials on left0.71.02.4-0.3-0.1-0.3-0.1-1.21.2-1.21.2-1.1-0.5-0.5-1.61.5-1.21.0
Reaction time mean3.34.512.20.5-0.60.3-0.62.6-2.62.9-2.92.93.53.01.6-1.11.70.4
Reaction time mean AUC3.54.612.00.8-0.90.6-0.92.7-2.62.9-2.92.93.52.91.7-1.01.70.3
Median of all reaction times2.02.87.80.5-0.80.4-0.82.0-2.02.3-2.22.42.82.21.2-0.91.10.7
Reaction time omissions3.85.111.71.2-1.11.0-1.12.9-2.82.9-2.92.73.33.41.9-0.92.20.2
Reaction time false alarm rate0.30.41.30.1-0.20.1-0.20.8-0.80.9-0.80.90.40.40.8-1.1-0.20.5
Reaction time premature initiation rate1.92.65.90.9-0.81.2-0.8-1.81.7-2.01.9-2.0-2.4-2.4-1.30.9-1.9-0.2
Reaction time premature initiations2.94.16.90.4-0.50.7-0.5-2.52.5-2.62.6-2.6-2.6-2.6-2.21.8-2.50.6
Std. dev. reaction times5.37.214.30.10.3-0.20.33.5-3.43.7-3.63.63.83.72.5-1.92.6-0.7
Reaction time trials completed0.71.02.4-0.3-0.1-0.3-0.1-1.21.2-1.21.2-1.1-0.5-0.5-1.61.5-1.21.0
Reaction time trials AUC0.81.12.6-0.2-0.2-0.2-0.2-1.31.3-1.31.3-1.2-0.6-0.6-1.61.6-1.31.1
Social response proportion0.10.10.4-0.30.4-0.30.4-0.20.2-0.10.20.20.60.1-0.60.40.10.6
Social responses0.20.21.5-0.30.4-0.20.4-0.20.2-0.20.2-0.3-0.6-0.40.0-0.70.3-1.2
Social time0.81.04.70.8-1.70.9-1.7-0.30.3-0.20.20.20.7-0.2-0.80.9-1.02.2
Conditioned locomotion0.91.13.71.7-1.91.8-1.9-0.00.0-0.10.1-0.5-0.3-1.10.30.70.4-0.3
Cocaine response after cond. corrected0.70.81.41.0-0.60.9-0.61.0-1.01.0-1.01.11.20.80.9-0.70.9-0.1
Cocaine response after cond. not corrected0.60.61.21.0-1.11.1-1.10.6-0.60.7-0.70.91.00.40.4-0.3-0.20.9
Cocaine response before conditioning0.60.72.90.3-1.20.5-1.2-0.60.6-0.60.6-0.6-0.7-1.0-0.60.3-1.71.1
Saline control response0.91.24.31.3-1.51.2-1.5-0.50.6-0.80.8-1.0-0.4-0.3-0.62.1-0.41.4
Condit. Reinf. active minus inactive responses1.11.44.4-0.4-0.8-0.4-0.81.2-1.21.4-1.41.82.11.40.6-0.50.21.4
Condit. Reinf. active-inactive response ratio2.22.36.60.1-0.8-0.0-0.81.9-1.82.0-2.02.12.61.91.3-0.91.20.4
Condit. Reinf. active responses0.60.96.9-0.9-0.0-0.9-0.0-0.30.4-0.10.20.60.90.5-0.90.7-1.12.6
Condit. Reinf. inactive responses2.12.66.0-1.00.6-0.90.6-1.91.9-1.81.9-1.3-1.0-1.0-2.21.8-2.12.4
Condit. Reinf. lever presses1.42.04.7-0.4-0.8-0.5-0.81.7-1.71.9-1.92.02.21.91.0-0.90.40.7
Condit. Reinf. lever reinforcers received0.60.86.3-1.00.1-1.00.1-0.30.3-0.10.20.60.90.4-0.80.5-1.02.5
Pavlov. Cond. lever latency0.40.50.80.50.80.40.8-0.70.7-0.80.8-0.9-0.6-0.5-0.60.90.8-0.5
Pavlov. Cond. magazine entry latency0.20.30.6-0.80.5-0.70.50.3-0.30.5-0.50.60.50.60.1-0.8-0.4-0.0
Pavlov. Cond. change in total contacts1.52.04.8-1.2-0.2-1.2-0.21.4-1.41.7-1.72.22.01.70.8-1.3-0.81.7
Pavlov. Cond. index score0.60.81.9-0.8-0.1-0.7-0.11.0-1.01.2-1.21.41.21.10.8-1.2-0.30.3
Pavlov. Cond. latency score0.60.81.8-1.00.2-1.00.20.9-0.91.1-1.11.41.21.10.6-1.3-0.20.2
Pavlov. Cond. lever contacts0.20.30.7-0.4-0.9-0.3-0.90.5-0.60.6-0.60.50.20.30.6-0.7-0.70.4
Pavlov. Cond. magazine entry number1.01.22.41.1-0.51.1-0.5-1.11.2-1.41.3-1.4-1.1-1.4-1.01.6-0.30.4
Pavlov. Cond. intertrial magazine entries0.30.31.90.5-0.20.4-0.2-0.50.5-0.70.6-0.5-0.1-0.3-0.61.40.30.5
Pavlov. Cond. lever-magazine prob. diff.0.50.71.6-0.8-0.0-0.8-0.00.8-0.81.0-1.01.31.11.00.6-1.1-0.40.4
Pavlov. Cond. response bias0.60.81.4-0.5-0.8-0.4-0.81.0-1.01.1-1.11.20.80.90.9-1.1-0.50.6
Conditioned reinforcement - actives0.10.10.3-0.20.3-0.20.3-0.10.1-0.00.00.10.4-0.0-0.1-0.10.10.6
Conditioned reinforcement - inactives0.30.31.1-1.00.8-1.00.8-0.0-0.10.1-0.10.3-0.1-0.20.1-0.7-0.50.5
Conditioned locomotion0.81.01.9-0.80.9-1.00.91.0-1.01.1-1.11.21.31.40.7-0.81.2-0.1
Intermittent access intake day 1-15 change0.50.51.8-0.60.3-0.60.3-0.80.8-0.90.8-1.0-1.4-1.1-0.20.3-0.3-0.1
Intermittent access intake escalation0.10.10.7-0.2-0.1-0.3-0.1-0.30.3-0.40.3-0.5-0.8-0.70.20.00.0-0.1
Intermittent access intake escalation 20.20.20.6-0.60.3-0.70.3-0.30.4-0.30.3-0.2-0.2-0.2-0.30.5-0.30.8
Intermitt. access day 1 inactive lever presses0.40.41.51.2-0.91.2-0.9-0.40.4-0.40.4-0.4-0.4-0.6-0.30.70.00.2
Intermitt. access day 15 inactive lever presses2.62.95.2-0.61.3-0.51.3-2.22.2-2.12.1-1.5-1.6-1.9-2.31.3-2.01.6
Intermitt. access escalation Index1.21.13.4-1.71.8-1.71.8-0.80.7-0.80.8-0.3-0.7-0.6-0.3-0.2-0.80.2
Intermittent access day 1 total infusions0.91.12.8-1.21.7-1.21.7-0.70.8-0.50.6-0.10.50.4-1.20.6-1.01.6
Intermittent access day 15 total infusions1.01.13.6-1.71.9-1.71.9-0.70.7-0.70.7-0.4-0.5-0.3-0.5-0.1-0.50.5
Intermittent access terminal intake (last 3 days)2.12.35.8-2.02.4-2.02.4-1.41.4-1.21.3-0.8-0.6-0.5-1.30.9-1.21.6
Intermittent access total infusions1.51.64.7-1.62.2-1.62.2-1.11.1-0.91.0-0.7-0.3-0.3-1.20.7-1.01.2
Intermittent access day 1 locomotion0.50.51.3-0.71.2-0.71.20.4-0.40.6-0.50.71.01.10.1-0.4-0.00.4
Intermittent access day 15 total locomotion0.30.31.1-0.20.7-0.20.70.4-0.40.4-0.40.1-0.00.50.7-0.80.7-1.1
Intermittent access total locomotion0.30.31.4-0.41.2-0.41.20.3-0.30.4-0.30.20.50.80.3-0.30.5-0.6
Intermittent access standard deviation0.30.31.0-0.70.5-0.70.5-0.50.5-0.50.5-0.6-1.0-0.5-0.20.2-0.20.5
Cocaine induced anxiety1.01.22.4-1.40.9-1.40.91.1-1.11.3-1.21.31.21.50.4-1.00.40.2
Post-drug Anxiety1.01.12.7-0.90.8-0.90.81.2-1.11.3-1.21.31.61.60.3-0.61.0-0.0
Baseline Anxiety0.20.20.40.6-0.30.7-0.3-0.30.4-0.40.4-0.5-0.2-0.4-0.40.50.1-0.2
Lifetime Intake1.51.74.1-1.62.0-1.62.0-1.21.2-1.01.1-0.7-0.2-0.3-1.40.7-1.31.5
Incentive Sensitization - Responses0.60.61.7-1.01.3-1.01.30.4-0.40.5-0.50.90.90.70.2-0.60.30.1
Incentive Sensitization - Breakpoint0.60.62.0-1.01.4-1.01.40.4-0.40.5-0.50.91.00.70.1-0.50.30.2
Progressive ratio test 1 active lever presses0.40.41.4-0.71.2-0.71.2-0.60.6-0.50.5-0.5-0.1-0.0-0.70.2-0.70.7
Progressive ratio test 1 breakpoint0.40.41.3-0.71.1-0.71.1-0.50.5-0.40.4-0.4-0.00.1-0.60.2-0.60.7
Progressive ratio test 1 inactive lever presses0.70.81.6-0.50.3-0.40.3-1.21.2-1.01.1-0.8-0.6-0.9-1.00.7-1.31.2
Progressive ratio test 2 active lever presses1.21.35.3-1.82.3-1.92.3-0.30.3-0.20.20.20.30.4-0.5-0.3-0.50.8
Progressive ratio test 2 breakpoint1.21.45.8-1.92.4-1.92.4-0.40.4-0.30.30.10.20.2-0.5-0.3-0.50.5
Progressive ratio test 2 inactive lever presses1.11.34.4-1.32.1-1.22.1-1.01.0-0.90.9-0.5-0.5-0.6-1.10.3-0.90.9
Total sessions with >9 infusions0.10.10.5-0.00.4-0.00.4-0.20.2-0.00.1-0.20.50.5-0.20.4-0.20.7
Short access day 1 total inactive lever presses0.20.31.2-0.61.1-0.71.1-0.30.3-0.40.4-0.1-0.2-0.3-0.40.10.00.3
Short access day 10 total inactive lever presses0.30.30.90.9-1.00.9-1.0-0.00.1-0.20.2-0.6-0.8-0.40.00.30.4-0.6
Short access day 1 total infusions0.60.71.1-0.60.8-0.50.8-1.01.0-0.90.9-0.8-0.4-0.7-1.00.5-1.10.8
Short access day 10 total infusions0.60.61.5-0.91.1-0.91.1-0.70.7-0.50.6-0.30.2-0.0-0.90.5-1.21.2
Short access total infusions1.21.32.8-1.11.2-1.01.2-1.21.2-1.11.1-0.8-0.2-0.4-1.40.9-1.51.7
Short access day 1 locomotion0.90.93.7-1.41.9-1.41.90.1-0.20.2-0.20.5-0.10.40.4-1.3-0.3-0.2
Short access day 10 total locomotion1.82.03.40.40.00.30.01.7-1.81.8-1.81.71.61.81.7-1.61.3-0.9
Short access total locomotion0.30.41.6-0.81.2-0.81.2-0.10.10.1-0.00.10.30.4-0.1-0.2-0.50.6
Compulsive drug intake1.21.22.00.5-1.20.4-1.21.4-1.41.4-1.41.11.31.20.9-0.41.1-0.4
One hour access (0.3 mA shock)0.50.62.0-1.41.4-1.41.40.2-0.20.3-0.30.40.40.7-0.2-0.5-0.30.5
One hour access (shock baseline)2.12.54.4-1.62.1-1.52.1-1.61.6-1.51.5-1.2-1.1-0.9-1.70.7-2.01.5
Number of responses in last shaping day1.71.74.1-1.72.0-1.62.0-1.31.2-1.21.2-1.1-1.2-1.0-1.00.1-1.40.1
Context. condit. distance diff. score0.70.94.2-0.10.6-0.10.6-0.10.0-0.30.3-0.5-1.8-0.81.0-1.30.8-2.0
Locomotion velocity, session 12.72.97.4-2.72.2-2.72.2-1.51.6-1.51.5-1.0-0.9-0.3-1.80.9-1.31.2
Locomotion distance, session 11.01.34.6-2.11.7-2.11.7-0.70.6-0.50.5-0.2-0.30.2-1.10.1-1.10.7
Locomotion velocity, session 21.61.84.4-1.21.2-1.11.2-1.61.6-1.41.5-1.4-0.7-0.6-2.11.6-1.50.7
Locomotion distance, session 20.60.92.2-1.20.8-1.20.8-0.80.9-0.80.8-0.6-0.1-0.1-1.51.1-1.31.2
Locomotion velocity, session 30.10.10.3-0.20.1-0.20.1-0.50.5-0.50.5-0.3-0.2-0.4-0.50.3-0.40.4
Locomotion distance, session 30.20.20.9-0.60.4-0.50.4-0.10.10.1-0.10.60.5-0.1-0.5-0.6-0.90.6
Stereotopy head waving bouts, day 30.60.81.5-0.30.3-0.30.3-1.11.1-1.21.2-1.1-0.9-0.8-0.81.2-0.50.8
Stereotopy head waving duration, day 30.20.20.90.2-0.10.2-0.1-0.40.4-0.70.6-0.9-1.0-0.50.10.50.4-0.4
Locomotion velocity, session 70.20.20.8-0.50.3-0.50.3-0.50.5-0.40.5-0.2-0.1-0.4-0.70.4-0.70.9
Locomotion distance, session 70.40.51.1-0.10.30.00.3-0.90.9-0.80.8-0.6-0.4-1.0-0.90.3-1.00.6
Stereotopy head waving bouts, day 71.31.55.0-2.22.0-2.22.00.1-0.20.2-0.30.5-0.40.50.6-1.6-0.2-0.9
Stereotopy head waving duration, day 71.11.44.8-2.12.0-2.22.00.1-0.20.2-0.20.4-0.50.50.5-1.30.0-0.9
Locomotion velocity, session 80.30.33.20.40.10.40.10.3-0.30.2-0.3-0.2-0.3-0.20.3-0.50.6-1.8
Locomotion distance, session 80.20.31.2-0.40.6-0.40.6-0.40.3-0.50.5-0.7-1.1-0.5-0.1-0.2-0.0-0.8
Degree of sensitization distance0.40.40.90.4-0.10.4-0.1-0.80.8-0.80.8-0.9-0.6-0.7-0.61.0-0.30.5
Degree of sensitization stereotypy1.61.85.3-1.81.7-1.81.70.8-0.91.0-1.01.20.10.91.1-2.30.2-1.6
Condit. Reinf. active minus inactive responses1.01.25.00.4-0.80.3-0.81.0-1.01.3-1.21.32.21.50.10.30.31.3
Condit. Reinf. active-inactive response ratio1.61.76.20.6-1.00.5-1.01.4-1.31.5-1.51.72.51.70.80.10.91.1
Condit. Reinf. active responses0.81.02.81.0-1.31.0-1.30.9-0.81.0-0.90.61.71.2-0.00.80.41.1
Condit. Reinf. inactive responses0.40.41.30.6-0.40.6-0.4-0.50.5-0.60.6-1.2-0.9-0.6-0.80.9-0.40.2
Incentive salience index mean1.21.45.71.1-1.21.1-1.21.1-1.01.3-1.21.12.41.50.20.60.60.9
Condit. Reinf. lever presses0.60.82.21.5-1.31.5-1.30.6-0.50.6-0.60.21.30.7-0.00.90.60.0
Time in familiar zone, hab. session 11.31.24.2-2.01.9-2.11.90.2-0.20.3-0.30.60.20.80.1-1.00.4-0.3
Time in novel zone, hab. session 10.60.61.81.0-0.91.1-0.9-0.30.3-0.50.5-0.6-1.4-1.20.6-0.3-0.3-0.5
Total zone transitions, hab. session 10.91.32.80.1-0.3-0.0-0.31.6-1.61.5-1.51.21.21.71.2-0.51.3-0.5
Total locomotion distance, hab. session 10.91.22.11.2-1.31.2-1.31.3-1.31.0-1.00.30.10.61.4-0.61.4-1.4
Locomotion velocity, hab. session 11.31.92.81.6-1.71.5-1.71.7-1.61.3-1.40.60.50.91.6-0.61.6-1.4
Time in familiar zone, hab. session 20.40.41.3-0.1-0.1-0.1-0.1-0.90.9-1.01.0-0.7-0.9-1.2-0.40.2-0.40.4
Time in novel zone, hab. session 21.41.42.6-0.60.5-0.70.51.5-1.51.6-1.61.60.91.41.3-1.60.6-0.6
Total zone transitions, hab. session 20.20.30.9-0.80.2-0.80.2-0.30.3-0.20.2-0.30.10.3-1.00.7-0.70.8
Total locomotion distance, hab. session 20.10.10.5-0.3-0.1-0.4-0.10.5-0.50.4-0.50.20.30.70.10.00.30.0
Locomotion velocity, hab. session 20.00.10.3-0.1-0.3-0.1-0.30.2-0.10.1-0.1-0.20.10.3-0.30.60.00.2
Novel to familiar place preference ratio2.22.47.10.5-0.20.4-0.21.8-1.91.5-1.60.8-0.41.12.5-2.02.0-2.7
Novelty place preference2.62.78.60.7-0.30.6-0.31.9-1.91.5-1.60.8-0.60.92.7-2.22.1-2.9
Time in novel zone, NPP test2.62.88.70.6-0.20.5-0.21.9-2.01.5-1.60.8-0.70.92.8-2.42.1-3.0
Total zone transitions, NPP test0.50.82.9-0.60.3-0.50.3-0.80.8-0.60.6-0.40.3-0.1-1.71.1-1.51.3
Total locomotion distance, NPP test0.40.51.8-0.40.0-0.40.0-0.60.7-0.60.6-0.50.0-0.1-1.31.1-1.01.2
Locomotion velocity, NPP test0.40.62.1-0.1-0.3-0.0-0.3-0.70.7-0.60.6-0.50.1-0.2-1.41.3-1.31.4
Pavlov. Cond. lever latency0.20.21.9-0.3-0.0-0.3-0.0-0.20.2-0.40.4-0.3-1.4-0.70.3-0.4-0.30.2
Pavlov. Cond. magazine entry latency1.31.73.2-0.71.0-0.71.01.3-1.31.6-1.51.51.81.80.9-1.31.1-1.2
Pavlov. Cond. change in total contacts0.10.20.5-0.00.3-0.10.3-0.10.10.1-0.0-0.20.70.5-0.50.60.5-0.7
Pavlov. Cond. index score0.50.71.6-0.91.3-0.91.30.4-0.40.6-0.60.51.31.1-0.1-0.20.7-1.0
Pavlov. Cond. latency score0.40.51.6-0.61.1-0.71.10.1-0.10.4-0.30.31.31.0-0.30.10.5-0.6
Pavlov. Cond. lever contacts0.20.21.30.30.20.30.2-0.10.10.1-0.0-0.21.10.5-0.50.90.6-0.5
Pavlov. Cond. magazine entry number1.51.94.21.6-2.11.6-2.1-0.80.8-1.01.0-1.1-1.2-1.6-0.51.3-1.21.8
Pavlov. Cond. intertrial magazine entries0.50.62.30.9-1.31.0-1.30.2-0.20.3-0.30.30.60.0-0.40.5-0.91.5
Pavlov. Cond. lever-magazine prob. diff.0.50.61.4-0.71.1-0.71.10.3-0.30.6-0.50.41.21.1-0.0-0.10.8-1.0
Pavlov. Cond. response bias1.01.33.0-0.71.3-0.81.30.9-0.91.1-1.10.91.41.50.6-0.91.3-1.7
Bone: apparent density0.81.45.81.7-1.01.7-1.00.7-0.70.3-0.4-0.5-1.0-0.41.5-0.61.1-2.4
Bone surface0.10.20.80.9-0.60.9-0.60.2-0.20.1-0.1-0.2-0.20.00.40.10.2-0.3
Bone volume0.20.41.41.2-0.61.1-0.6-0.00.0-0.30.3-0.7-0.6-0.20.30.70.5-0.5
Bone: connectivity density0.50.82.70.9-1.01.1-1.00.7-0.80.6-0.70.1-0.6-0.51.2-1.30.1-1.6
Bone: cortical apparent density1.72.25.10.5-0.10.5-0.1-1.81.8-2.12.1-2.2-2.3-1.8-1.01.6-0.70.1
Bone: cortical area0.50.72.61.6-1.21.6-1.20.2-0.1-0.20.1-0.6-0.20.10.11.20.80.2
Bone: cortical porosity1.61.76.31.6-2.51.7-2.51.1-1.11.1-1.11.01.10.00.9-0.3-0.10.5
Bone: cortical porosity2.02.18.62.1-2.92.3-2.90.9-0.90.8-0.80.60.8-0.20.80.20.00.5
Bone: cortical thickness0.91.45.32.3-2.02.3-2.00.3-0.2-0.10.1-0.7-0.3-0.10.31.30.9-0.0
Bone: cortical thickness0.20.30.7-0.50.8-0.60.8-0.30.4-0.40.5-0.6-0.30.4-0.10.70.4-0.3
Bone: cortical tissue density1.72.25.20.4-0.00.5-0.0-1.81.9-2.12.1-2.2-2.3-1.8-1.01.5-0.60.1
Bone: elastic displacement0.91.02.81.1-1.71.2-1.71.1-1.01.1-1.10.81.00.60.6-0.40.30.1
Bone: elastic work0.50.72.31.2-1.51.2-1.50.10.0-0.10.1-0.30.30.1-0.31.00.01.1
Bone: endosteal estimation0.20.41.4-0.60.7-0.80.70.3-0.20.3-0.30.41.21.00.10.71.00.5
Bone: endosteal perimeter0.20.30.8-0.60.7-0.60.7-0.40.5-0.40.4-0.20.30.1-0.80.7-0.20.9
Bone: final force0.60.92.61.5-1.61.4-1.60.7-0.60.5-0.50.10.80.50.61.00.70.5
Bone: final moment0.61.03.11.5-1.81.4-1.80.8-0.70.5-0.60.10.70.40.70.90.60.5
Bone: marrow area0.20.51.4-0.70.8-0.90.80.4-0.30.4-0.30.41.21.10.20.51.20.2
Bone: maximum diameter0.20.41.10.30.10.30.1-0.60.6-0.80.8-1.0-0.8-0.5-0.60.9-0.10.2
Bone: maximum force0.50.92.81.5-1.41.4-1.40.4-0.30.1-0.1-0.30.60.60.21.71.00.9
Bone: maximum moment0.50.92.41.5-1.51.3-1.50.5-0.40.2-0.2-0.20.60.60.31.50.91.0
Bone: minimum diameter0.50.92.91.0-0.90.9-0.90.9-0.80.8-0.70.71.71.20.20.81.20.9
Bone: periosteal estimation0.20.31.70.4-0.00.2-0.00.4-0.30.2-0.1-0.10.70.80.21.11.30.4
Bone: periosteal perimeter0.30.51.31.0-0.71.0-0.7-0.40.4-0.60.6-0.7-0.3-0.3-0.61.1-0.21.0
Bone: post-yield work0.60.83.2-0.70.7-0.80.70.6-0.60.8-0.81.21.81.40.10.20.21.2
Bone: stiffness0.30.52.31.2-0.71.0-0.7-0.20.4-0.50.5-0.70.00.0-0.01.50.70.5
Bone: tissue strength2.12.07.91.7-2.81.8-2.80.8-0.80.7-0.70.70.90.00.30.5-0.52.1
Bone: trabecular number1.11.89.51.4-1.01.6-1.00.5-0.70.3-0.4-0.6-1.7-1.01.7-1.30.6-3.1
Bone: trabecular spacing1.72.27.6-2.11.6-2.11.6-1.11.2-0.91.00.00.30.1-1.70.7-1.72.8
Bone: trabecular thickness0.50.71.41.2-0.81.1-0.8-0.40.5-0.70.7-1.2-0.9-0.6-0.10.90.5-1.0
Bone: trabecular tissue density1.01.56.20.10.00.00.0-1.31.4-1.61.6-1.6-0.9-0.3-1.22.5-0.31.1
Breakpoint value in progressive ratio session1.82.06.20.10.3-0.00.31.6-1.61.6-1.61.10.41.01.9-2.11.7-2.5
Distance traveled before self-admin1.21.34.1-2.02.0-2.02.0-0.50.4-0.40.4-0.2-1.1-0.4-0.1-0.6-0.7-0.1
Distance traveled after self-admin0.70.82.5-1.61.2-1.61.20.3-0.40.4-0.40.60.10.30.5-1.50.1-0.9
Delta time in closed arm before/after self-admin2.62.54.10.7-1.20.5-1.21.9-2.01.8-1.91.81.61.42.0-1.52.0-1.3
Delta time in open arm before/after self-admin0.90.92.7-1.61.6-1.61.60.1-0.10.3-0.20.10.21.0-0.6-0.0-0.60.6
Diff in mean of infusions in LGA sessions0.60.72.4-0.10.0-0.10.00.9-1.01.0-1.00.90.60.61.1-1.50.7-1.1
Extinction: sum of active levers before priming2.93.04.71.4-1.51.4-1.52.0-2.02.2-2.11.92.11.91.7-1.31.4-0.3
Active lever presses in extinction session 61.81.83.9-0.3-0.2-0.6-0.21.6-1.51.6-1.62.01.91.71.4-1.41.3-0.1
Delta distance traveled before/after self-admin0.10.10.3-0.0-0.2-0.0-0.20.2-0.10.1-0.10.40.50.20.3-0.60.3-0.4
Delta ambulatory time before/after self-admin0.20.20.70.3-0.40.3-0.40.3-0.20.2-0.20.30.50.30.3-0.40.6-0.8
Time in closed arm before self-admin3.23.66.3-0.30.7-0.10.7-2.52.5-2.52.5-2.2-2.3-2.3-2.21.5-2.11.1
Time in closed arm after self-admin1.11.22.00.9-0.50.9-0.5-1.31.3-1.41.4-1.4-1.4-1.4-0.81.0-0.60.2
Time in open arm before self-admin4.24.57.90.6-0.90.5-0.92.5-2.72.4-2.62.41.91.82.8-2.52.4-2.4
Time in open arm after self-admin2.32.54.1-1.30.9-1.30.91.9-1.92.0-2.01.91.52.01.4-1.91.1-0.9
Sum of active levers in priming session hrs 5-62.72.74.8-1.71.3-1.91.31.8-1.71.9-1.82.01.82.21.3-1.61.20.1
Time to tail flick, vehicle, before self-admin1.31.32.90.4-0.30.4-0.3-1.31.4-1.31.4-1.1-0.7-1.1-1.41.6-1.01.7
Time to tail flick, vehicle, after self-admin1.01.13.4-1.81.2-1.81.20.3-0.30.5-0.51.11.10.9-0.2-0.4-0.51.7
Time to tail flick, test, before self-admin1.21.23.21.4-0.91.3-0.91.1-1.10.9-1.00.40.00.61.2-1.01.5-1.8
Time to tail flick, test, after self-admin0.91.05.31.3-0.51.3-0.50.6-0.60.3-0.4-0.1-0.8-0.11.1-1.11.0-2.3
Delta time to tail flick, vehicle, before/after SA0.70.71.3-1.00.3-1.10.30.8-0.80.9-0.91.01.11.10.4-0.4-0.31.0
Delta time to tail flick, test, before/after SA0.40.41.0-0.60.9-0.60.9-0.40.4-0.50.5-0.5-1.0-0.5-0.1-0.3-0.2-0.8
Ambulatory time before self-admin1.31.43.2-1.51.8-1.51.8-1.01.0-1.01.0-0.7-1.5-0.9-0.5-0.2-1.40.6
Ambulatory time after self-admin0.50.62.6-1.60.8-1.50.8-0.0-0.00.1-0.10.3-0.2-0.10.3-1.3-0.5-0.4
Total heroin consumption0.70.83.1-0.81.2-0.81.20.2-0.30.1-0.20.1-1.0-0.21.1-1.50.7-1.8
Area under the delay curve4.64.99.02.3-1.72.1-1.72.5-2.52.4-2.41.61.72.02.7-1.33.0-2.7
Delay disc. indifference point, 0s delay0.10.10.4-0.00.20.00.2-0.20.3-0.20.2-0.00.20.0-0.60.5-0.30.6
Delay disc. indifference point, 16s delay6.06.011.23.4-3.13.2-3.12.3-2.32.2-2.31.21.51.62.6-0.92.8-2.7
Delay disc. indifference point, 2s delay2.52.84.62.0-1.22.0-1.21.9-1.91.8-1.81.21.31.41.7-1.02.1-2.0
Delay disc. indifference point, 24s delay3.43.35.62.4-1.92.2-1.92.0-2.01.7-1.80.80.81.42.3-0.72.3-2.0
Delay disc. indifference point, 4s delay1.31.34.30.8-0.30.8-0.31.3-1.31.2-1.20.70.61.11.4-1.01.7-2.1
Delay disc. indifference point, 8s delay1.81.84.10.9-0.60.8-0.61.6-1.61.6-1.61.11.41.51.6-0.62.0-1.7
Delay discount exponential model param4.75.09.0-2.31.8-2.21.8-2.52.5-2.42.4-1.5-1.6-1.9-2.71.3-3.02.8
Delay discount hyperbolic model param4.44.68.4-2.31.7-2.11.7-2.42.4-2.32.4-1.5-1.6-1.9-2.61.3-2.92.6
Fecal boli incidents, locomotor time 10.30.31.00.4-0.70.3-0.70.1-0.00.1-0.00.41.00.3-0.20.70.30.9
Change in fecal boli incidents, locomotor task0.50.52.3-1.10.0-1.00.00.7-0.70.7-0.70.5-0.00.30.7-1.5-0.1-0.4
Time >=10cm from walls, locomotor time 10.70.73.1-1.81.3-1.81.3-0.10.1-0.20.2-0.0-0.40.3-0.4-0.2-0.30.5
Bouts of movement, locomotor time 11.41.63.71.7-1.61.9-1.6-0.90.9-1.01.0-1.3-1.0-1.4-1.21.0-1.00.0
Total resting periods, locomotor time 11.01.12.91.6-1.41.7-1.4-0.60.7-0.80.8-0.9-0.7-1.1-1.00.9-0.70.1
Rest time, locomotor task time 10.20.20.5-0.30.2-0.40.20.4-0.30.3-0.3-0.00.60.7-0.50.70.10.5
Distance moved, locomotor task time 10.50.61.7-0.81.2-0.71.2-0.30.2-0.30.3-0.4-1.1-0.30.5-0.90.1-1.3
Vertical activity count, locomotor time 10.30.31.3-0.70.5-0.70.5-0.0-0.0-0.0-0.00.0-0.6-0.30.7-1.10.3-1.1
Time >=10cm from walls, locomotor time 20.90.92.3-1.50.8-1.50.80.7-0.70.7-0.71.31.31.10.4-0.4-0.20.9
Bouts of movement, locomotor time 22.72.97.40.8-1.40.8-1.4-2.02.0-2.12.1-2.0-2.3-2.7-1.00.9-1.80.5
Total resting periods, locomotor time 22.62.86.80.8-1.40.9-1.4-1.91.9-2.02.0-2.0-2.3-2.6-1.11.0-1.70.5
Rest time, locomotor task time 20.20.30.70.7-0.60.7-0.6-0.10.2-0.20.2-0.8-0.5-0.2-0.50.9-0.0-0.5
Distance moved, locomotor task time 20.40.41.4-0.71.2-0.71.20.3-0.30.3-0.30.50.50.70.5-0.70.2-0.4
Vertical activity count, locomotor time 20.30.41.1-1.01.1-1.01.10.00.00.1-0.10.40.80.50.0-0.00.20.2
Weight adjusted by age2.02.24.70.00.40.10.4-1.81.8-1.81.8-1.5-1.0-1.3-2.22.0-1.42.0
Seeking ratio, delayed vs. immediate footshock0.20.30.70.1-0.50.0-0.50.7-0.70.5-0.60.5-0.20.10.9-0.80.6-0.2
Locomotion in novel chamber0.30.41.6-0.81.2-0.91.20.1-0.10.2-0.20.30.40.7-0.0-0.00.4-0.2
Locomotion in novel chamber post-restriction0.70.82.31.5-1.31.5-1.3-0.50.6-0.50.5-0.9-0.7-0.7-0.60.7-0.40.4
Progressive ratio0.30.32.3-0.9-0.0-0.8-0.0-0.00.00.0-0.00.30.2-0.1-0.20.0-0.81.5
Food seeking constrained by brief footshock2.32.75.01.3-1.11.2-1.12.1-2.11.9-2.01.51.61.81.7-1.02.2-1.5
Seeking ratio, punishment vs. effort1.92.36.31.7-0.81.5-0.81.6-1.61.5-1.50.91.11.51.5-0.82.3-2.5
Run reversals in cocaine runway, females1.61.63.5-0.91.2-0.81.2-1.41.4-1.51.5-1.8-1.9-1.4-0.70.9-0.4-0.6
Run reversals in cocaine runway, males0.50.51.21.1-1.01.0-1.00.5-0.50.5-0.50.41.10.20.50.40.8-0.4
Latency to leave start box in cocaine runway0.40.40.80.7-0.90.7-0.90.5-0.60.6-0.70.60.6-0.10.6-0.60.2-0.6
Latency to leave start box in cocaine runway, F0.10.10.6-0.30.3-0.20.3-0.40.3-0.30.2-0.1-0.3-0.8-0.1-0.4-0.5-0.0
Latency to leave start box in cocaine runway, M2.01.94.31.8-2.11.7-2.11.3-1.31.4-1.40.91.40.71.2-0.41.0-0.8
Cd content in liver0.91.02.0-0.30.2-0.30.2-1.31.3-1.21.3-1.0-0.8-1.0-1.41.0-1.11.1
Co content in liver1.21.55.0-2.12.1-2.22.10.0-0.10.3-0.20.90.60.80.1-1.20.10.2
Cu content in liver0.80.92.9-1.51.2-1.41.2-0.10.00.2-0.20.90.40.2-0.5-0.9-1.71.3
Fe content in liver0.70.82.31.2-1.51.2-1.50.7-0.60.7-0.70.81.10.10.40.0-0.10.9
K content in liver0.30.30.60.7-0.70.8-0.7-0.30.3-0.50.4-0.6-0.8-0.6-0.00.4-0.5-0.1
Mg content in liver0.60.61.00.7-0.80.7-0.80.9-0.91.0-1.00.90.60.30.9-1.0-0.1-0.1
Mn content in liver0.20.20.70.8-0.70.8-0.70.1-0.1-0.0-0.00.10.0-0.50.4-0.00.4-0.2
Na content in liver1.01.13.60.10.20.10.2-1.21.1-1.41.4-1.6-1.9-1.3-0.50.7-0.5-0.7
Rb content in liver1.11.42.90.5-1.10.5-1.11.4-1.51.5-1.61.71.10.51.4-1.70.20.1
Se content in liver0.70.93.90.1-0.20.3-0.2-1.11.0-0.90.9-0.6-0.6-1.5-1.10.3-2.01.0
Sr content in liver0.40.41.4-0.81.2-0.81.2-0.20.1-0.10.1-0.1-0.4-0.2-0.0-0.8-0.1-0.9
Zn content in liver0.30.30.9-0.40.2-0.40.20.6-0.60.7-0.70.80.90.80.4-0.30.10.5