Ints4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000012552 0.03 0.02 4.3e-03 0.02 0.01 0 0.01 3.3e-03 1.2e-02 1.6e-01 8.8e-03
2 Adipose mRNA stability ENSRNOG00000012552 0.03 0.02 1.8e-03 0.02 0.02 0.01 0.02 1.3e-03 1.7e-03 8.1e-03 2.2e-03
3 Brain gene expression ENSRNOG00000012552 0.04 0.03 3.8e-04 0.03 0.04 0.03 0.03 2.0e-03 3.4e-04 1.0e-03 3.5e-04
4 Brain mRNA stability ENSRNOG00000012552 0.11 0.06 4.4e-08 0.08 0.09 0.08 0.08 3.5e-08 8.0e-09 5.9e-08 4.9e-08
5 LHb gene expression ENSRNOG00000012552 0.22 0.14 5.4e-03 0.01 -0.01 -0.01 -0.01 2.0e-01 4.6e-01 9.4e-01 7.2e-01
6 Liver gene expression ENSRNOG00000012552 0.51 0.14 0.0e+00 0.23 0.37 0.36 0.36 9.1e-25 1.8e-42 6.2e-41 4.9e-42
7 Liver mRNA stability ENSRNOG00000012552 0.16 0.07 5.6e-17 0.11 0.14 0.12 0.13 5.3e-12 3.7e-15 1.9e-13 3.1e-14
8 NAcc gene expression ENSRNOG00000012552 0.07 0.05 1.0e-03 0.04 0.04 0.03 0.03 5.7e-04 9.9e-04 3.3e-03 1.6e-03
9 PL mRNA stability ENSRNOG00000012552 0.05 0.03 9.4e-04 0.04 0.03 0.03 0.03 4.4e-04 1.2e-03 2.9e-03 1.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail0.62.06.72.6-0.51.6-1.20.30.40.1-2.5-0.8
BMI without tail2.96.119.24.4-0.63.0-1.90.91.30.7-4.3-1.0
Body weight1.04.213.63.7-0.42.5-1.60.31.30.7-3.6-0.5
Epididymis fat weight1.12.58.42.9-0.52.0-0.90.41.10.9-2.5-0.7
Glucose0.40.61.4-0.80.9-1.00.8-1.20.40.40.60.8
Heart weight0.91.31.7-1.11.1-1.21.3-1.21.11.11.00.9
Left kidney weight0.51.44.00.81.10.30.4-1.12.01.8-0.71.3
Right kidney weight0.20.61.80.80.40.7-0.1-0.61.31.2-0.70.7
Tail length1.13.47.62.61.01.5-0.2-0.62.82.3-2.50.8
Length with tail0.62.46.52.50.21.8-0.9-0.11.71.2-2.50.3
Length without tail0.10.30.7-0.1-0.60.2-0.70.3-0.7-0.90.0-0.3
Liver weight, left0.50.92.81.7-0.31.0-0.70.50.20.0-1.6-0.8
Liver weight, right3.05.010.73.3-1.73.0-2.21.9-0.2-0.5-3.2-2.0
Parametrial fat weight1.83.57.62.8-1.52.1-1.81.6-0.4-0.8-2.7-1.9
Retroperitoneal fat weight3.210.731.55.6-1.54.1-2.81.81.00.3-5.4-2.0
Intraocular pressure3.65.19.0-2.42.4-3.02.5-2.41.01.22.32.4
Extensor digitorum longus weight0.20.71.51.10.50.10.1-1.11.10.8-1.20.8
Soleus weight0.30.92.51.6-0.01.2-0.6-0.01.00.7-1.60.3
Tibialis anterior weight0.10.51.71.3-0.20.6-0.5-0.10.30.1-1.3-0.0
Tibia length0.51.32.2-1.51.0-1.51.4-0.90.50.71.40.8
Number of licking bursts2.32.73.61.6-1.91.9-1.91.5-1.3-1.4-1.7-1.5
Food consumed during 24 hour testing period1.51.83.4-1.91.5-1.51.1-0.90.20.51.71.8
Times rat made contact with spout0.70.71.51.2-0.61.2-1.00.9-0.3-0.4-1.2-0.2
Mean time between licks in bursts2.53.57.1-0.72.1-0.81.7-2.02.62.70.82.2
Mean num. licks in bursts1.92.23.4-1.21.8-1.61.7-1.41.21.41.31.7
Std. dev. time between licks in bursts0.60.82.41.60.21.0-0.30.11.10.9-1.20.1
Water consumed over 24 hours1.01.22.00.6-1.11.2-1.41.3-1.2-1.3-0.8-0.7
Indifference point 0 sec1.11.73.0-0.61.5-1.31.3-1.71.51.30.41.7
Indifference point AUC0.20.20.40.30.5-0.20.5-0.50.70.6-0.40.5
Indifference point function ln k0.50.72.6-1.60.2-0.70.2-0.3-0.4-0.41.60.4
Indifference point function log k0.50.72.6-1.60.2-0.70.2-0.3-0.4-0.41.60.4
Delay discounting total patch changes 0 sec1.01.62.8-0.51.4-1.31.3-1.71.31.30.41.6
Delay discounting total patch changes 12 sec0.71.02.00.50.9-0.41.0-0.91.41.4-0.61.2
Delay discounting total patch changes 18 sec1.41.83.4-0.21.6-0.91.3-1.51.71.70.01.8
Delay discounting total patch changes 24 sec0.81.02.10.61.0-0.41.0-0.91.41.4-0.80.9
Delay discounting total patch changes 6 sec0.00.00.1-0.10.1-0.3-0.0-0.2-0.0-0.20.00.1
Delay discounting time to switch 0 sec2.53.85.51.2-2.42.0-2.12.2-2.0-2.0-0.9-2.2
Delay discounting water rate 0 sec1.93.04.0-1.32.0-1.91.9-2.01.61.61.11.9
Delay discounting water rate 12 sec1.11.62.6-1.31.6-1.61.2-1.30.90.81.21.2
Delay discounting water rate 18 sec0.81.11.6-0.41.3-1.11.0-1.31.21.10.41.2
Delay discounting water rate 24 sec0.91.32.6-1.61.1-1.61.0-1.00.10.21.41.0
Delay discounting water rate 6 sec0.60.82.2-1.50.8-1.20.7-0.50.10.11.30.9
Locomotor activity0.20.30.90.4-0.50.9-0.90.7-0.0-0.3-0.4-0.2
Locomotor testing distance0.40.72.20.20.70.10.4-0.61.51.3-0.40.9
Locomotor testing rearing0.81.34.21.80.11.2-0.4-0.01.41.1-2.10.1
Light reinforcement 11.63.04.92.2-1.71.9-1.61.7-0.9-1.0-2.1-2.0
Light reinforcement 20.40.51.30.8-0.80.5-0.40.8-0.6-0.5-0.7-1.1
Reaction time number correct0.81.12.20.2-1.20.6-1.11.2-1.4-1.5-0.1-1.1
Reaction time mean minus median0.20.20.70.30.5-0.10.2-0.40.80.7-0.20.6
Reaction time mean minus median AUC0.10.10.20.20.4-0.20.2-0.20.40.30.00.3
Reaction time num false alarms0.81.23.21.8-0.71.0-0.90.7-0.3-0.5-1.8-0.9
Reaction time num false alarms AUC0.20.30.80.9-0.30.4-0.30.4-0.3-0.3-0.8-0.4
Reaction time trials correct on left0.81.12.20.2-1.20.6-1.11.2-1.4-1.5-0.1-1.1
Reaction time trials on left0.81.12.20.2-1.30.6-1.11.2-1.4-1.5-0.0-1.0
Reaction time mean0.20.30.60.8-0.80.7-0.50.4-0.1-0.2-0.6-0.5
Reaction time mean AUC0.20.30.60.6-0.80.6-0.50.4-0.3-0.3-0.5-0.5
Median of all reaction times0.30.41.00.5-1.00.7-0.50.6-0.4-0.4-0.4-0.6
Reaction time omissions0.10.10.50.1-0.0-0.10.2-0.50.70.60.10.5
Reaction time false alarm rate0.10.20.70.80.20.10.2-0.10.30.4-0.8-0.1
Reaction time premature initiation rate0.81.02.81.30.30.9-0.0-0.21.71.4-1.30.3
Reaction time premature initiations0.30.51.11.0-0.30.9-0.40.30.90.7-0.9-0.0
Std. dev. reaction times0.30.41.10.80.30.30.1-0.41.00.8-0.60.4
Reaction time trials completed0.81.12.20.2-1.30.6-1.11.2-1.4-1.5-0.0-1.0
Reaction time trials AUC0.71.01.80.4-1.20.7-1.11.1-1.2-1.3-0.2-1.0
Social response proportion2.02.23.41.5-1.71.9-1.61.7-1.0-1.0-1.4-1.3
Social responses1.31.73.61.9-1.21.8-1.51.0-0.1-0.4-1.9-0.8
Social time2.22.84.71.2-2.01.7-1.72.2-1.3-1.4-1.2-2.1
Conditioned locomotion0.10.20.4-0.5-0.2-0.2-0.3-0.0-0.6-0.60.50.1
Cocaine response after cond. corrected0.10.20.4-0.10.1-0.30.6-0.40.60.60.00.4
Cocaine response after cond. not corrected0.10.10.3-0.4-0.1-0.40.6-0.10.20.30.40.1
Cocaine response before conditioning0.50.61.2-0.4-0.90.3-0.50.9-1.1-0.90.5-0.8
Saline control response0.40.51.40.20.9-0.30.4-0.81.20.9-0.40.9
Condit. Reinf. active minus inactive responses3.94.87.9-0.52.4-1.82.3-2.62.82.70.62.5
Condit. Reinf. active-inactive response ratio2.32.43.3-0.61.7-1.51.7-1.81.71.70.61.8
Condit. Reinf. active responses4.66.311.6-0.52.8-1.82.5-3.03.43.20.62.8
Condit. Reinf. inactive responses1.01.23.4-0.01.2-0.20.7-1.31.81.70.11.2
Condit. Reinf. lever presses9.112.518.2-2.93.8-3.63.6-4.33.23.22.84.2
Condit. Reinf. lever reinforcers received5.17.212.3-0.83.0-2.12.8-3.23.53.40.82.9
Pavlov. Cond. lever latency11.315.521.73.3-4.14.3-4.14.7-3.5-3.4-3.2-4.5
Pavlov. Cond. magazine entry latency4.34.98.2-2.32.2-2.92.5-2.51.41.52.22.1
Pavlov. Cond. change in total contacts6.79.312.9-2.53.2-3.33.2-3.62.82.82.43.4
Pavlov. Cond. index score9.612.616.8-3.23.7-4.03.8-4.13.03.03.03.9
Pavlov. Cond. latency score8.811.115.0-3.13.5-3.83.6-3.92.72.72.93.6
Pavlov. Cond. lever contacts10.114.119.7-3.24.0-4.03.8-4.43.43.33.14.3
Pavlov. Cond. magazine entry number10.212.618.23.1-3.84.3-4.04.1-2.7-2.8-3.0-3.8
Pavlov. Cond. intertrial magazine entries1.31.74.92.2-0.71.9-1.10.90.50.4-1.9-0.5
Pavlov. Cond. lever-magazine prob. diff.9.111.816.0-3.03.6-3.83.7-4.03.03.02.83.8
Pavlov. Cond. response bias12.016.621.8-3.54.3-4.44.3-4.73.63.63.44.6
Conditioned reinforcement - actives2.72.74.7-2.21.4-2.02.1-1.40.61.12.11.0
Conditioned reinforcement - inactives0.10.10.2-0.4-0.3-0.00.0-0.1-0.3-0.20.5-0.1
Conditioned locomotion2.02.44.5-2.11.3-1.91.9-1.10.40.82.11.2
Intermittent access intake day 1-15 change2.12.14.8-2.21.2-1.71.4-1.20.40.62.21.1
Intermittent access intake escalation2.62.55.2-2.31.4-1.81.6-1.40.60.82.31.3
Intermittent access intake escalation 20.60.60.8-0.80.7-0.70.9-0.70.60.70.80.7
Intermitt. access day 1 inactive lever presses0.30.40.80.4-0.80.8-0.50.9-0.5-0.4-0.4-0.6
Intermitt. access day 15 inactive lever presses0.10.10.3-0.5-0.2-0.1-0.0-0.1-0.3-0.20.5-0.0
Intermitt. access escalation Index0.30.30.50.0-0.60.4-0.70.6-0.7-0.7-0.1-0.4
Intermittent access day 1 total infusions1.21.31.9-0.81.3-1.21.3-1.41.11.20.81.2
Intermittent access day 15 total infusions3.84.27.2-2.71.9-2.32.2-1.91.01.32.71.9
Intermittent access terminal intake (last 3 days)2.32.53.8-1.91.5-1.61.7-1.60.91.21.91.6
Intermittent access total infusions1.71.82.5-1.41.3-1.31.6-1.40.91.21.41.4
Intermittent access day 1 locomotion0.30.30.6-0.80.4-0.70.7-0.2-0.20.10.80.3
Intermittent access day 15 total locomotion1.51.62.1-1.41.3-1.41.5-1.20.91.11.41.2
Intermittent access total locomotion0.80.91.3-0.91.0-0.91.1-0.80.70.90.81.0
Intermittent access standard deviation0.10.10.2-0.30.2-0.10.4-0.30.30.50.40.5
Cocaine induced anxiety1.41.62.20.9-1.41.3-1.41.5-1.1-1.2-0.9-1.4
Post-drug Anxiety0.10.10.2-0.0-0.50.3-0.40.3-0.2-0.30.0-0.4
Baseline Anxiety2.52.63.3-1.61.6-1.81.7-1.81.31.41.61.7
Lifetime Intake1.92.12.9-1.61.3-1.51.7-1.51.01.31.61.4
Incentive Sensitization - Responses3.43.45.7-0.92.0-1.52.0-2.42.02.20.92.0
Incentive Sensitization - Breakpoint3.23.25.5-1.01.9-1.51.9-2.31.92.10.91.9
Progressive ratio test 1 active lever presses0.10.10.2-0.4-0.30.1-0.10.2-0.4-0.30.4-0.3
Progressive ratio test 1 breakpoint0.10.10.2-0.2-0.40.2-0.10.4-0.5-0.40.2-0.4
Progressive ratio test 1 inactive lever presses0.10.10.3-0.50.1-0.20.3-0.20.20.30.50.3
Progressive ratio test 2 active lever presses2.82.94.7-1.01.9-1.52.0-2.21.82.01.01.8
Progressive ratio test 2 breakpoint2.02.23.6-0.81.6-1.21.7-1.91.61.80.81.5
Progressive ratio test 2 inactive lever presses1.21.42.0-1.11.0-1.01.3-1.41.11.21.11.3
Total sessions with >9 infusions1.11.22.4-1.50.7-1.11.2-1.10.50.81.51.0
Short access day 1 total inactive lever presses0.40.40.6-0.80.5-0.70.7-0.70.40.50.70.5
Short access day 10 total inactive lever presses1.21.31.90.9-1.21.2-1.41.1-1.0-1.1-0.9-1.3
Short access day 1 total infusions1.51.62.3-1.21.0-1.11.5-1.41.21.41.21.3
Short access day 10 total infusions1.51.62.6-0.81.3-1.21.6-1.41.31.50.81.4
Short access total infusions0.80.91.5-0.90.7-0.81.2-1.00.91.10.90.9
Short access day 1 locomotion2.12.25.1-2.21.0-1.81.6-1.10.30.62.31.0
Short access day 10 total locomotion0.10.10.3-0.30.5-0.30.4-0.10.40.40.30.5
Short access total locomotion0.10.10.1-0.3-0.30.00.20.3-0.3-0.10.3-0.2
Compulsive drug intake0.00.00.10.2-0.30.1-0.00.1-0.1-0.0-0.2-0.1
One hour access (0.3 mA shock)2.73.24.2-1.31.8-1.52.0-2.11.82.01.32.0
One hour access (shock baseline)1.61.82.2-1.31.4-1.31.4-1.51.11.31.31.4
Number of responses in last shaping day0.50.51.11.0-0.10.70.2-0.01.01.1-1.0-0.1
Context. condit. distance diff. score2.73.35.6-1.51.8-2.42.3-2.11.11.41.51.8
Locomotion velocity, session 10.60.61.7-1.30.4-1.00.7-0.3-0.3-0.11.30.6
Locomotion distance, session 10.30.41.0-0.70.2-0.80.8-0.50.20.31.00.2
Locomotion velocity, session 20.70.81.3-0.91.1-0.91.0-1.00.70.80.51.2
Locomotion distance, session 20.00.00.00.1-0.10.1-0.20.00.0-0.1-0.0-0.1
Locomotion velocity, session 30.30.40.7-0.70.6-0.70.6-0.60.20.30.70.8
Locomotion distance, session 31.71.93.4-1.41.4-1.91.6-1.40.50.81.51.2
Stereotopy head waving bouts, day 32.42.95.01.5-1.82.2-2.02.0-1.2-1.2-1.3-1.6
Stereotopy head waving duration, day 30.30.40.8-0.1-0.60.5-0.90.7-0.8-0.90.2-0.4
Locomotion velocity, session 70.30.30.7-0.50.6-0.70.7-0.60.20.30.80.6
Locomotion distance, session 70.91.22.2-0.11.2-1.11.3-1.51.11.20.31.0
Stereotopy head waving bouts, day 70.10.20.6-0.80.1-0.30.20.1-0.4-0.20.60.4
Stereotopy head waving duration, day 70.40.51.2-1.00.6-0.60.5-0.60.20.30.91.1
Locomotion velocity, session 85.46.511.1-2.72.7-3.32.8-2.71.21.42.52.8
Locomotion distance, session 81.31.93.0-1.21.4-1.71.6-1.70.81.01.31.4
Degree of sensitization distance0.70.72.11.5-0.20.9-0.2-0.10.90.7-1.4-0.2
Degree of sensitization stereotypy1.92.03.8-2.01.3-1.71.5-1.20.30.61.71.6
Condit. Reinf. active minus inactive responses0.80.93.11.60.20.5-0.0-0.31.00.8-1.8-0.1
Condit. Reinf. active-inactive response ratio0.70.72.41.50.00.6-0.2-0.40.90.6-1.50.1
Condit. Reinf. active responses0.60.83.41.5-0.10.7-0.40.10.50.3-1.8-0.4
Condit. Reinf. inactive responses0.10.10.40.30.00.2-0.10.1-0.1-0.1-0.7-0.1
Incentive salience index mean0.50.61.40.90.7-0.00.5-0.61.21.1-1.00.4
Condit. Reinf. lever presses0.50.71.5-0.51.2-0.91.0-0.60.80.90.50.8
Time in familiar zone, hab. session 10.00.00.10.00.3-0.20.20.00.10.2-0.30.2
Time in novel zone, hab. session 10.20.20.50.7-0.60.7-0.60.00.1-0.1-0.3-0.2
Total zone transitions, hab. session 10.81.12.4-0.1-1.00.4-1.01.1-1.4-1.60.3-1.4
Total locomotion distance, hab. session 15.17.312.23.5-2.63.4-2.72.5-0.9-1.1-3.4-2.8
Locomotion velocity, hab. session 14.66.611.03.3-2.53.2-2.52.4-0.9-1.1-3.2-2.8
Time in familiar zone, hab. session 20.90.92.4-0.01.3-0.70.7-1.20.90.90.31.6
Time in novel zone, hab. session 20.10.10.2-0.3-0.2-0.20.40.00.10.20.0-0.4
Total zone transitions, hab. session 20.30.30.9-0.1-0.5-0.1-0.40.2-0.8-0.90.3-0.9
Total locomotion distance, hab. session 23.24.28.32.9-1.92.6-2.01.6-0.3-0.6-2.8-2.1
Locomotion velocity, hab. session 23.64.89.53.1-2.02.8-2.11.7-0.3-0.7-3.0-2.3
Novel to familiar place preference ratio0.20.20.60.3-0.50.3-0.30.6-0.3-0.4-0.2-0.8
Novelty place preference0.00.00.20.1-0.30.1-0.10.3-0.1-0.1-0.1-0.4
Time in novel zone, NPP test0.00.00.0-0.10.0-0.20.10.00.10.00.1-0.2
Total zone transitions, NPP test0.30.41.0-1.00.0-0.80.3-0.3-0.4-0.41.0-0.3
Total locomotion distance, NPP test2.12.96.52.5-1.72.1-1.21.2-0.0-0.1-2.5-1.9
Locomotion velocity, NPP test2.84.18.12.9-2.02.5-1.51.5-0.3-0.4-2.8-2.3
Pavlov. Cond. lever latency1.21.52.61.1-1.31.1-1.21.3-1.0-1.2-1.1-1.6
Pavlov. Cond. magazine entry latency1.21.52.5-0.31.4-1.01.4-1.51.61.60.41.3
Pavlov. Cond. change in total contacts1.81.93.1-0.71.4-1.21.7-1.71.41.60.61.8
Pavlov. Cond. index score2.02.64.1-0.81.8-1.21.6-1.81.91.90.92.0
Pavlov. Cond. latency score1.82.43.7-0.81.7-1.21.6-1.81.71.80.91.9
Pavlov. Cond. lever contacts1.41.63.0-0.91.5-0.91.3-1.31.41.50.91.7
Pavlov. Cond. magazine entry number1.72.23.30.7-1.61.2-1.51.7-1.7-1.7-0.7-1.8
Pavlov. Cond. intertrial magazine entries0.81.01.50.9-1.01.1-1.01.2-0.7-0.7-1.2-1.0
Pavlov. Cond. lever-magazine prob. diff.1.82.33.8-0.81.7-1.21.5-1.71.61.71.01.9
Pavlov. Cond. response bias0.70.91.5-0.51.1-0.60.9-0.91.21.20.41.2
Bone: apparent density0.10.10.3-0.2-0.1-0.1-0.10.5-0.5-0.50.2-0.3
Bone surface1.42.43.3-1.11.7-1.71.8-1.71.31.41.11.8
Bone volume0.81.42.3-0.61.5-1.21.3-1.21.21.20.61.4
Bone: connectivity density0.40.61.6-1.20.4-1.00.8-0.1-0.4-0.11.30.3
Bone: cortical apparent density0.30.30.70.8-0.40.6-0.70.4-0.3-0.5-0.8-0.4
Bone: cortical area0.71.02.00.91.0-0.51.0-1.11.41.3-0.80.8
Bone: cortical porosity0.30.41.4-1.2-0.40.0-0.10.3-0.5-0.41.00.0
Bone: cortical porosity0.30.31.0-1.0-0.50.2-0.20.5-0.6-0.40.9-0.0
Bone: cortical thickness0.20.31.41.2-0.30.3-0.10.10.10.0-1.1-0.2
Bone: cortical thickness0.91.12.4-0.50.8-1.21.5-1.21.01.10.70.8
Bone: cortical tissue density0.30.30.60.7-0.50.7-0.80.4-0.4-0.5-0.7-0.4
Bone: elastic displacement0.30.40.8-0.3-0.70.2-0.50.5-0.9-0.90.3-0.8
Bone: elastic work0.70.92.0-1.3-0.8-0.2-0.40.4-1.4-1.31.3-0.6
Bone: endosteal estimation1.02.24.5-0.11.9-0.91.5-1.52.12.10.11.5
Bone: endosteal perimeter2.04.07.1-0.72.7-1.82.2-2.22.42.40.72.0
Bone: final force0.10.20.5-0.30.3-0.70.6-0.60.10.20.30.3
Bone: final moment0.10.20.5-0.30.4-0.70.7-0.60.20.30.30.4
Bone: marrow area0.81.83.90.01.7-0.81.4-1.32.01.90.01.3
Bone: maximum diameter1.42.64.0-0.22.0-1.41.8-1.92.02.00.21.7
Bone: maximum force0.30.61.3-0.70.7-1.11.0-1.00.20.30.80.6
Bone: maximum moment0.40.71.3-0.80.8-1.21.0-1.00.30.40.80.7
Bone: minimum diameter0.81.53.51.41.1-0.00.8-0.91.91.7-1.30.7
Bone: periosteal estimation1.63.35.90.12.1-1.32.0-2.02.42.4-0.11.8
Bone: periosteal perimeter1.11.83.5-0.01.9-1.11.2-1.51.71.60.11.5
Bone: post-yield work0.00.10.2-0.1-0.1-0.20.0-0.0-0.4-0.30.3-0.1
Bone: stiffness0.00.10.20.4-0.2-0.20.0-0.2-0.3-0.3-0.4-0.3
Bone: tissue strength1.81.84.3-0.6-1.50.6-1.11.2-2.1-1.90.6-1.4
Bone: trabecular number0.30.51.2-0.4-0.60.1-0.41.0-1.1-1.00.4-0.8
Bone: trabecular spacing0.30.40.6-0.50.6-0.60.8-0.50.70.80.60.5
Bone: trabecular thickness0.10.20.60.70.20.1-0.3-0.30.30.1-0.80.2
Bone: trabecular tissue density2.02.85.72.3-1.42.1-1.91.3-0.5-0.9-2.4-1.3
Breakpoint value in progressive ratio session0.10.10.2-0.10.1-0.50.3-0.4-0.2-0.10.00.2
Distance traveled before self-admin0.10.10.30.4-0.40.3-0.30.1-0.2-0.2-0.4-0.6
Distance traveled after self-admin1.51.73.10.2-1.51.0-1.41.4-1.5-1.6-0.2-1.7
Delta time in closed arm before/after self-admin0.40.41.10.40.7-0.20.1-0.71.10.7-0.40.8
Delta time in open arm before/after self-admin1.11.01.7-0.21.2-0.91.2-1.21.21.30.31.0
Diff in mean of infusions in LGA sessions2.42.73.81.8-1.61.7-1.91.5-1.4-1.6-1.8-1.2
Extinction: sum of active levers before priming0.30.30.50.20.7-0.30.4-0.70.70.7-0.20.5
Active lever presses in extinction session 60.30.30.8-0.90.2-0.70.6-0.4-0.10.10.90.5
Delta distance traveled before/after self-admin0.60.71.2-0.4-0.80.6-1.01.0-1.0-1.10.5-0.6
Delta ambulatory time before/after self-admin0.80.81.9-0.7-0.80.3-0.90.9-1.3-1.40.7-0.7
Time in closed arm before self-admin0.70.82.7-1.6-0.2-0.60.20.1-0.8-0.61.60.2
Time in closed arm after self-admin0.90.93.0-1.70.1-1.00.4-0.0-0.8-0.71.70.4
Time in open arm before self-admin1.21.31.91.4-1.01.3-1.21.1-0.6-0.8-1.4-1.2
Time in open arm after self-admin0.60.72.21.50.10.7-0.2-0.10.70.6-1.5-0.1
Sum of active levers in priming session hrs 5-60.30.30.60.8-0.40.7-0.70.4-0.3-0.3-0.8-0.3
Time to tail flick, vehicle, before self-admin0.30.30.70.4-0.50.8-0.80.5-0.2-0.4-0.4-0.6
Time to tail flick, vehicle, after self-admin1.61.73.1-1.81.3-1.51.2-1.10.60.61.81.3
Time to tail flick, test, before self-admin0.60.61.00.61.0-0.80.9-0.80.80.8-0.60.5
Time to tail flick, test, after self-admin1.01.12.10.21.3-0.81.1-1.01.51.4-0.21.0
Delta time to tail flick, vehicle, before/after SA2.52.44.9-2.21.3-2.01.6-1.20.40.62.21.4
Delta time to tail flick, test, before/after SA0.20.10.2-0.1-0.50.4-0.50.5-0.3-0.30.1-0.5
Ambulatory time before self-admin0.00.00.1-0.1-0.1-0.30.1-0.1-0.3-0.20.1-0.2
Ambulatory time after self-admin1.21.32.8-0.4-1.20.4-1.11.1-1.7-1.70.4-1.3
Total heroin consumption0.00.00.2-0.00.1-0.20.0-0.2-0.1-0.1-0.00.4
Area under the delay curve0.90.91.9-1.30.9-1.10.8-0.90.30.41.41.0
Delay disc. indifference point, 0s delay0.50.51.0-0.30.8-0.50.8-0.70.91.00.30.8
Delay disc. indifference point, 16s delay0.70.72.4-1.50.4-0.90.3-0.3-0.3-0.31.50.5
Delay disc. indifference point, 2s delay0.80.81.3-0.81.0-1.01.0-1.00.60.80.81.1
Delay disc. indifference point, 24s delay0.10.10.2-0.4-0.0-0.3-0.20.0-0.4-0.50.5-0.2
Delay disc. indifference point, 4s delay1.61.72.9-0.81.5-1.21.3-1.51.31.40.81.7
Delay disc. indifference point, 8s delay1.21.32.8-1.70.9-1.31.0-1.00.40.41.71.1
Delay discount exponential model param0.80.81.71.3-0.81.1-0.80.8-0.3-0.3-1.3-0.9
Delay discount hyperbolic model param1.01.11.61.3-1.01.2-1.01.0-0.5-0.6-1.3-1.1
Fecal boli incidents, locomotor time 12.52.84.8-1.71.6-2.02.2-1.51.11.41.71.5
Change in fecal boli incidents, locomotor task2.22.13.50.7-1.61.5-1.91.6-1.4-1.7-0.7-1.5
Time >=10cm from walls, locomotor time 10.70.71.5-1.10.7-1.20.9-0.80.00.21.10.8
Bouts of movement, locomotor time 10.30.30.7-0.30.7-0.80.4-0.90.40.30.30.6
Total resting periods, locomotor time 10.30.30.7-0.70.5-0.90.3-0.6-0.0-0.10.60.4
Rest time, locomotor task time 10.30.30.9-0.90.3-0.90.4-0.3-0.2-0.20.90.3
Distance moved, locomotor task time 10.50.61.50.60.60.20.4-0.71.21.2-0.50.8
Vertical activity count, locomotor time 10.30.30.80.40.50.10.3-0.60.90.9-0.30.5
Time >=10cm from walls, locomotor time 20.80.91.4-0.11.2-0.91.1-0.91.11.20.11.0
Bouts of movement, locomotor time 20.20.20.6-0.60.3-0.00.1-0.40.40.40.60.8
Total resting periods, locomotor time 20.20.20.4-0.60.2-0.00.1-0.30.30.20.70.7
Rest time, locomotor task time 21.41.62.30.7-1.51.1-1.21.5-1.4-1.4-0.8-1.5
Distance moved, locomotor task time 22.63.15.3-0.42.0-1.21.8-1.92.22.30.52.1
Vertical activity count, locomotor time 21.61.83.70.11.5-0.61.3-1.51.91.90.01.5
Weight adjusted by age0.91.02.40.41.1-0.10.8-1.01.51.6-0.51.0
Seeking ratio, delayed vs. immediate footshock0.00.00.2-0.1-0.30.00.10.1-0.2-0.00.1-0.4
Locomotion in novel chamber0.60.71.8-1.30.5-1.20.9-0.3-0.3-0.11.30.5
Locomotion in novel chamber post-restriction2.42.95.9-2.11.6-2.41.9-1.40.20.52.21.6
Progressive ratio0.60.71.9-0.90.7-1.41.0-0.80.20.20.90.4
Food seeking constrained by brief footshock0.40.41.60.60.50.10.3-0.51.31.0-0.50.4
Seeking ratio, punishment vs. effort0.60.71.91.3-0.31.4-0.60.30.80.7-1.20.0
Run reversals in cocaine runway, females1.41.43.01.70.60.60.0-0.81.71.4-1.70.8
Run reversals in cocaine runway, males1.61.53.3-1.81.1-1.61.0-1.00.20.31.81.2
Latency to leave start box in cocaine runway1.31.42.11.1-1.41.5-1.21.2-0.8-0.8-1.1-1.3
Latency to leave start box in cocaine runway, F0.70.81.91.4-0.91.2-0.60.7-0.00.0-1.4-0.7
Latency to leave start box in cocaine runway, M1.11.02.0-0.2-1.20.7-1.01.1-1.4-1.30.3-1.1
Cd content in liver0.40.51.71.1-0.50.7-0.50.40.0-0.1-1.3-0.5
Co content in liver1.51.83.2-0.31.7-0.91.4-1.41.81.80.31.4
Cu content in liver0.70.82.40.20.9-0.00.5-1.01.51.4-0.01.0
Fe content in liver0.70.91.3-0.80.8-0.81.1-1.10.91.00.91.0
K content in liver0.60.61.20.4-0.81.1-1.01.1-0.6-0.6-0.2-0.7
Mg content in liver0.00.00.1-0.20.2-0.10.10.00.20.20.30.2
Mn content in liver0.91.02.3-0.1-1.10.5-0.81.4-1.5-1.40.2-1.0
Na content in liver0.40.40.8-0.8-0.70.2-0.20.8-0.9-0.60.8-0.0
Rb content in liver0.50.71.3-0.21.1-0.70.6-1.11.10.90.40.8
Se content in liver1.92.23.70.3-1.91.4-1.51.9-1.7-1.6-0.6-1.6
Sr content in liver0.60.50.9-0.80.7-1.00.8-0.70.30.40.80.7
Zn content in liver1.51.72.7-0.51.4-1.01.3-1.51.71.60.71.4