Hub : Genes

Wdr18

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000016733 0.03 0.02 3.1e-04 0.03 0.02 0.03 0.02 7.2e-04 1.4e-03 5.7e-04 1.6e-03
2 Adipose alternative polyA ENSRNOT00000093580 0.03 0.02 9.1e-04 0.02 0.01 0.02 0.01 2.9e-03 8.1e-03 4.3e-03 7.9e-03
3 Adipose isoform ratio ENSRNOT00000016733 0.03 0.02 4.2e-04 0.02 0.02 0.02 0.02 9.1e-04 1.5e-03 2.3e-03 1.6e-03
4 Adipose isoform ratio ENSRNOT00000093580 0.04 0.03 9.5e-05 0.03 0.03 0.03 0.03 1.4e-04 2.6e-04 1.7e-04 1.9e-04
5 Adipose isoform ratio ENSRNOT00000093997 0.12 0.08 3.6e-14 0.11 0.11 0.11 0.11 2.1e-12 3.1e-12 1.3e-12 2.8e-12
6 BLA isoform ratio ENSRNOT00000016733 0.05 0.04 1.5e-03 0.07 0.04 0.03 0.04 1.7e-04 5.0e-03 7.1e-03 2.9e-03
7 Brain isoform ratio ENSRNOT00000016733 0.04 0.03 3.9e-03 0 0.01 0.02 0.01 1.6e-01 3.9e-02 4.1e-03 6.4e-02
8 LHb isoform ratio ENSRNOT00000093997 0.11 0.08 5.4e-03 0.2 0.09 0.12 0.17 1.7e-05 4.6e-03 1.0e-03 8.0e-05
9 Liver alternative polyA ENSRNOT00000016733 0.03 0.02 1.3e-03 0.03 0.03 0.03 0.03 5.4e-04 5.3e-04 4.8e-04 5.9e-04
10 Liver alternative polyA ENSRNOT00000093580 0.02 0.02 5.9e-03 0.02 0.02 0.02 0.02 3.3e-03 4.7e-03 3.3e-03 5.0e-03
11 Liver gene expression ENSRNOG00000012379 0.11 0.07 9.6e-14 0.12 0.11 0.11 0.12 9.0e-13 1.6e-12 1.2e-12 1.1e-12
12 Liver isoform ratio ENSRNOT00000016733 0.02 0.02 2.2e-03 0.02 0.02 0.02 0.02 2.1e-03 6.4e-03 4.4e-03 5.8e-03
13 PL isoform ratio ENSRNOT00000016733 0.05 0.04 2.4e-04 0.04 0.05 0.05 0.05 5.3e-04 2.0e-04 1.1e-04 2.1e-04
14 PL isoform ratio ENSRNOT00000093580 0.05 0.04 3.6e-03 0.03 0.02 0.01 0.02 1.7e-03 1.0e-02 3.5e-02 6.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail6.621.323.2-4.54.6-4.64.64.8-4.64.14.8-4.54.6-4.5-4.6-4.84.7
BMI without tail2.34.99.0-2.12.1-2.12.12.1-2.11.73.0-2.12.1-1.8-2.1-2.62.6
Body weight1.25.26.1-2.32.3-2.32.32.3-2.32.12.5-2.32.3-2.1-2.3-2.32.3
Epididymis fat weight0.30.70.90.9-0.90.9-0.9-0.80.9-0.2-0.60.9-0.90.90.90.6-0.7
Glucose1.52.33.2-1.51.4-1.41.41.8-1.41.01.6-1.51.4-1.6-1.4-1.81.8
Heart weight0.30.40.70.8-0.80.8-0.8-0.20.80.1-0.20.8-0.80.30.8-0.10.0
Left kidney weight0.00.10.6-0.00.0-0.00.0-0.2-0.0-0.8-0.5-0.10.00.1-0.00.5-0.3
Right kidney weight1.23.64.11.8-1.91.9-1.9-2.01.9-2.0-2.01.8-1.91.91.92.0-1.8
Tail length3.09.011.43.0-3.13.1-3.1-3.43.1-2.3-2.53.0-3.13.43.12.9-2.8
Length with tail1.76.27.72.4-2.42.4-2.4-2.72.4-1.6-2.62.4-2.42.52.42.8-2.8
Length without tail0.10.20.90.1-0.00.0-0.0-0.30.00.3-0.90.1-0.00.10.00.8-0.9
Liver weight, left2.03.34.0-1.81.8-1.81.81.8-1.81.62.0-1.81.8-1.7-1.8-1.91.9
Liver weight, right1.52.53.2-1.71.8-1.81.81.4-1.81.21.4-1.71.8-1.4-1.8-1.21.2
Parametrial fat weight0.30.50.90.8-0.80.8-0.8-0.90.80.1-0.40.8-0.80.90.80.6-0.5
Retroperitoneal fat weight0.20.61.0-0.80.8-0.80.80.7-0.80.21.0-0.80.8-0.7-0.8-0.80.9
Intraocular pressure0.30.41.30.5-0.50.5-0.50.30.51.00.70.5-0.5-0.00.5-1.01.1
Extensor digitorum longus weight4.216.824.1-4.14.1-4.14.14.0-4.13.24.9-4.04.1-3.6-4.1-4.44.5
Soleus weight9.026.128.3-5.25.2-5.25.25.3-5.23.65.2-5.25.2-5.1-5.2-5.35.2
Tibialis anterior weight1.13.94.6-2.12.1-2.12.11.8-2.11.72.1-2.12.1-1.6-2.1-1.81.7
Tibia length0.92.52.91.7-1.71.7-1.7-1.61.7-0.7-1.41.7-1.71.61.71.5-1.4
Number of licking bursts0.10.20.70.1-0.20.2-0.20.20.20.40.70.2-0.20.10.2-0.60.9
Food consumed during 24 hour testing period0.60.71.9-0.70.7-0.70.70.9-0.7-0.61.1-0.70.7-0.8-0.7-1.01.4
Times rat made contact with spout0.20.31.3-0.30.3-0.30.30.4-0.3-0.60.9-0.30.3-0.2-0.3-0.81.1
Mean time between licks in bursts4.15.76.62.5-2.62.6-2.6-2.42.6-0.9-2.22.6-2.62.52.62.2-2.2
Mean num. licks in bursts0.10.10.6-0.30.4-0.40.40.1-0.4-0.80.0-0.30.4-0.2-0.4-0.00.1
Std. dev. time between licks in bursts0.60.71.00.8-0.80.8-0.8-0.90.80.2-1.00.8-0.80.90.81.0-1.0
Water consumed over 24 hours0.60.81.0-1.01.0-1.01.00.8-1.0-0.70.5-1.01.0-0.9-1.0-0.50.7
Indifference point 0 sec0.20.30.9-0.60.5-0.50.50.5-0.51.00.3-0.60.5-0.6-0.5-0.30.3
Indifference point AUC0.60.80.90.9-0.90.9-0.9-0.80.9-0.6-0.80.9-0.90.80.90.8-0.7
Indifference point function ln k0.20.30.7-0.50.4-0.40.40.6-0.40.80.8-0.50.4-0.5-0.4-0.70.8
Indifference point function log k0.20.30.7-0.50.4-0.40.40.6-0.40.80.8-0.50.4-0.5-0.4-0.70.8
Delay discounting total patch changes 0 sec0.10.21.0-0.50.4-0.40.40.4-0.41.00.3-0.50.4-0.4-0.4-0.30.3
Delay discounting total patch changes 12 sec0.40.51.0-0.60.6-0.60.60.7-0.61.00.9-0.50.6-0.5-0.6-0.80.8
Delay discounting total patch changes 18 sec0.91.21.41.2-1.11.1-1.1-1.21.10.0-1.21.2-1.11.21.11.2-1.1
Delay discounting total patch changes 24 sec0.00.00.10.2-0.20.2-0.2-0.10.2-0.0-0.40.2-0.20.00.20.2-0.2
Delay discounting total patch changes 6 sec0.20.20.50.5-0.50.5-0.5-0.30.5-0.2-0.70.5-0.50.30.50.5-0.4
Delay discounting time to switch 0 sec1.32.03.0-1.71.7-1.71.70.9-1.7-1.50.2-1.71.7-1.3-1.7-0.2-0.1
Delay discounting water rate 0 sec0.61.08.50.4-0.40.4-0.40.10.42.91.10.4-0.40.50.4-0.81.1
Delay discounting water rate 12 sec1.42.16.2-0.80.9-0.90.91.5-0.92.52.2-0.80.9-1.0-0.9-2.12.4
Delay discounting water rate 18 sec0.81.14.10.9-0.90.9-0.9-0.00.92.01.30.9-0.90.70.9-1.11.4
Delay discounting water rate 24 sec1.11.59.20.0-0.00.0-0.00.70.03.02.00.1-0.0-0.10.0-1.82.0
Delay discounting water rate 6 sec0.50.71.71.0-0.90.9-0.9-0.40.91.30.51.0-0.90.70.9-0.40.7
Locomotor activity2.84.57.31.9-1.91.9-1.9-2.21.9-2.1-2.71.8-1.91.91.92.6-2.7
Locomotor testing distance1.62.74.11.6-1.61.6-1.6-1.71.6-1.5-2.01.5-1.61.41.61.9-2.0
Locomotor testing rearing0.10.21.20.3-0.30.3-0.3-0.10.31.10.30.3-0.30.20.3-0.30.3
Light reinforcement 15.810.613.93.2-3.23.2-3.2-3.43.2-2.8-3.73.1-3.23.03.23.6-3.7
Light reinforcement 22.12.84.21.6-1.61.6-1.6-1.61.6-1.5-2.01.6-1.61.41.61.7-2.0
Reaction time number correct0.71.04.7-0.40.4-0.40.40.8-0.42.21.6-0.40.4-0.4-0.4-1.41.7
Reaction time mean minus median0.70.91.31.0-1.11.1-1.1-0.81.1-0.6-0.51.1-1.11.01.10.6-0.6
Reaction time mean minus median AUC0.10.11.0-0.20.1-0.10.1-0.1-0.1-1.0-0.3-0.20.1-0.0-0.10.3-0.4
Reaction time num false alarms0.30.43.4-0.10.1-0.10.10.3-0.11.91.1-0.00.10.0-0.1-0.90.8
Reaction time num false alarms AUC0.40.64.1-0.10.1-0.10.10.4-0.12.01.3-0.10.10.0-0.1-1.00.9
Reaction time trials correct on left0.71.04.7-0.40.4-0.40.40.8-0.42.21.6-0.40.4-0.4-0.4-1.41.7
Reaction time trials on left0.71.04.3-0.40.4-0.40.40.8-0.42.11.6-0.40.4-0.4-0.4-1.41.7
Reaction time mean0.00.00.1-0.20.1-0.10.10.3-0.1-0.1-0.1-0.20.1-0.3-0.1-0.10.1
Reaction time mean AUC0.10.10.2-0.30.2-0.20.20.5-0.2-0.4-0.0-0.30.2-0.5-0.2-0.30.2
Median of all reaction times0.30.40.8-0.70.7-0.70.70.8-0.70.20.3-0.70.7-0.9-0.7-0.50.5
Reaction time omissions0.40.53.70.5-0.50.5-0.5-0.20.5-1.9-0.80.5-0.50.10.50.4-0.4
Reaction time false alarm rate0.00.00.3-0.10.1-0.10.10.1-0.10.60.4-0.10.1-0.0-0.1-0.2-0.0
Reaction time premature initiation rate1.01.42.01.4-1.41.4-1.4-0.91.4-0.2-0.81.4-1.41.11.40.6-0.5
Reaction time premature initiations0.81.11.71.3-1.31.3-1.3-0.61.31.00.01.3-1.31.01.3-0.10.4
Std. dev. reaction times0.20.20.40.5-0.60.6-0.6-0.30.6-0.3-0.30.5-0.60.40.60.3-0.2
Reaction time trials completed0.71.04.3-0.40.4-0.40.40.8-0.42.11.6-0.40.4-0.4-0.4-1.41.7
Reaction time trials AUC0.71.04.7-0.30.3-0.30.30.8-0.32.21.7-0.30.3-0.3-0.3-1.51.8
Social response proportion0.80.92.00.7-0.80.8-0.8-0.80.8-1.4-1.40.7-0.80.70.81.2-1.2
Social responses6.38.110.52.7-2.82.8-2.8-3.02.8-2.3-3.22.7-2.82.82.83.2-3.2
Social time0.60.81.1-0.90.9-0.90.91.0-0.90.80.6-0.90.9-1.1-0.9-0.70.6
Conditioned locomotion1.51.86.2-1.00.9-0.90.91.3-0.92.51.9-0.90.9-1.0-0.9-1.71.7
Cocaine response after cond. corrected5.05.711.6-2.12.0-2.02.02.7-2.00.93.4-2.02.0-2.3-2.0-3.23.4
Cocaine response after cond. not corrected5.35.911.8-2.12.1-2.12.12.6-2.11.63.4-2.12.1-2.2-2.1-3.33.4
Cocaine response before conditioning0.60.71.80.7-0.60.6-0.6-1.00.61.4-0.80.7-0.61.00.61.0-1.1
Saline control response0.10.11.4-0.20.2-0.20.20.3-0.21.20.3-0.20.2-0.2-0.2-0.30.3
Condit. Reinf. active minus inactive responses2.12.63.61.9-1.91.9-1.9-1.41.90.9-1.11.9-1.91.61.90.9-0.8
Condit. Reinf. active-inactive response ratio0.40.51.80.6-0.70.7-0.70.30.71.30.30.6-0.7-0.10.7-0.80.8
Condit. Reinf. active responses1.92.63.31.8-1.81.8-1.8-1.51.81.0-1.31.8-1.81.71.81.2-1.0
Condit. Reinf. inactive responses1.01.22.21.1-1.11.1-1.1-1.41.10.5-1.01.1-1.11.51.11.2-1.0
Condit. Reinf. lever presses2.12.93.81.9-1.91.9-1.9-1.61.91.1-1.21.9-1.91.71.91.2-1.2
Condit. Reinf. lever reinforcers received1.52.12.81.6-1.71.7-1.7-1.21.71.4-0.91.7-1.71.51.70.8-0.6
Pavlov. Cond. lever latency0.60.81.1-0.91.0-1.01.00.8-1.0-1.10.6-0.91.0-0.8-1.0-0.60.6
Pavlov. Cond. magazine entry latency0.40.50.70.6-0.60.6-0.6-0.80.6-0.8-0.50.6-0.60.90.60.7-0.7
Pavlov. Cond. change in total contacts0.60.81.21.0-1.11.1-1.1-0.61.10.9-0.61.1-1.10.71.10.4-0.4
Pavlov. Cond. index score0.60.81.01.0-1.01.0-1.0-0.91.00.6-0.61.0-1.01.01.00.7-0.6
Pavlov. Cond. latency score0.50.70.80.9-0.90.9-0.9-0.80.90.3-0.70.9-0.90.80.90.7-0.7
Pavlov. Cond. lever contacts0.60.91.71.0-1.01.0-1.0-0.81.01.3-0.41.0-1.00.91.00.4-0.4
Pavlov. Cond. magazine entry number0.60.81.2-0.90.9-0.90.91.0-0.90.10.7-0.90.9-1.1-0.9-0.91.0
Pavlov. Cond. intertrial magazine entries0.30.41.3-0.40.4-0.40.40.6-0.41.10.9-0.40.4-0.4-0.4-0.91.0
Pavlov. Cond. lever-magazine prob. diff.0.60.81.01.0-1.01.0-1.0-0.91.00.5-0.71.0-1.01.01.00.8-0.8
Pavlov. Cond. response bias1.52.02.61.6-1.61.6-1.6-1.41.60.9-0.91.6-1.61.51.61.0-0.9
Conditioned reinforcement - actives1.81.72.61.4-1.31.3-1.3-1.51.3-0.6-1.41.4-1.31.41.31.4-1.6
Conditioned reinforcement - inactives0.50.61.9-0.50.7-0.70.70.6-0.71.41.1-0.50.7-0.5-0.7-0.80.8
Conditioned locomotion6.88.18.92.9-2.92.9-2.9-2.92.9-2.1-2.82.9-2.92.82.92.8-3.0
Intermittent access intake day 1-15 change6.05.97.62.6-2.52.5-2.5-2.72.5-0.8-2.22.6-2.52.82.52.5-2.3
Intermittent access intake escalation5.75.67.82.6-2.62.6-2.6-2.62.6-0.3-1.72.6-2.62.82.62.0-1.9
Intermittent access intake escalation 26.96.98.72.9-2.92.9-2.9-2.82.9-0.2-2.02.9-2.92.92.92.2-2.1
Intermitt. access day 1 inactive lever presses0.10.10.20.4-0.40.4-0.4-0.30.40.40.30.5-0.40.40.4-0.10.1
Intermitt. access day 15 inactive lever presses0.50.60.80.8-0.80.8-0.8-0.80.80.2-0.50.8-0.80.90.80.6-0.6
Intermitt. access escalation Index0.40.40.6-0.70.8-0.80.80.4-0.8-0.1-0.1-0.70.8-0.6-0.8-0.00.1
Intermittent access day 1 total infusions0.00.00.1-0.20.1-0.10.10.3-0.10.10.2-0.20.1-0.4-0.1-0.20.1
Intermittent access day 15 total infusions1.82.02.61.6-1.61.6-1.6-1.51.60.1-1.01.6-1.61.61.61.2-1.1
Intermittent access terminal intake (last 3 days)0.91.01.41.0-1.01.0-1.0-1.21.00.1-0.81.0-1.01.21.01.0-1.0
Intermittent access total infusions0.20.20.30.5-0.50.5-0.5-0.50.50.5-0.20.5-0.50.50.50.3-0.3
Intermittent access day 1 locomotion0.40.40.60.8-0.70.7-0.7-0.70.70.1-0.50.8-0.70.70.70.6-0.5
Intermittent access day 15 total locomotion3.33.54.42.0-1.91.9-1.9-2.11.9-0.5-1.82.0-1.92.11.92.0-1.9
Intermittent access total locomotion0.80.91.21.0-0.90.9-0.9-1.10.90.1-1.01.0-0.91.00.91.1-1.1
Intermittent access standard deviation2.32.53.21.8-1.71.7-1.7-1.71.7-0.2-1.21.8-1.71.81.71.3-1.3
Cocaine induced anxiety0.50.51.60.4-0.40.4-0.4-0.70.4-0.9-1.30.4-0.40.40.41.2-1.2
Post-drug Anxiety0.50.61.60.5-0.50.5-0.5-0.70.5-1.2-1.30.4-0.50.50.51.2-1.3
Baseline Anxiety0.30.30.40.6-0.60.6-0.6-0.50.6-0.20.00.7-0.60.60.60.1-0.0
Lifetime Intake0.10.10.10.3-0.30.3-0.3-0.30.30.2-0.10.3-0.30.30.30.3-0.3
Incentive Sensitization - Responses0.10.11.00.3-0.20.2-0.2-0.20.21.00.20.3-0.20.30.2-0.00.1
Incentive Sensitization - Breakpoint0.10.10.80.4-0.30.3-0.3-0.30.30.90.10.4-0.30.40.30.1-0.0
Progressive ratio test 1 active lever presses0.10.10.5-0.00.1-0.10.10.1-0.10.70.5-0.00.10.0-0.1-0.30.5
Progressive ratio test 1 breakpoint0.10.10.6-0.20.2-0.20.20.2-0.20.80.6-0.20.2-0.0-0.2-0.30.6
Progressive ratio test 1 inactive lever presses0.00.10.40.2-0.10.1-0.1-0.30.1-0.6-0.20.2-0.10.20.10.3-0.1
Progressive ratio test 2 active lever presses0.20.20.90.5-0.40.4-0.4-0.40.40.90.10.5-0.40.50.40.10.0
Progressive ratio test 2 breakpoint0.20.20.40.5-0.40.4-0.4-0.50.40.7-0.20.5-0.40.50.40.3-0.3
Progressive ratio test 2 inactive lever presses0.00.00.10.1-0.00.0-0.0-0.20.00.1-0.20.1-0.00.10.00.3-0.4
Total sessions with >9 infusions0.10.10.1-0.30.3-0.30.30.1-0.3-0.40.0-0.30.3-0.2-0.30.00.0
Short access day 1 total inactive lever presses0.10.21.30.2-0.20.2-0.2-0.30.2-1.1-0.30.2-0.20.30.20.4-0.4
Short access day 10 total inactive lever presses0.00.00.30.0-0.20.2-0.20.00.2-0.60.20.0-0.2-0.00.2-0.20.2
Short access day 1 total infusions0.30.31.20.2-0.10.1-0.1-0.50.1-1.1-0.80.2-0.10.30.10.8-0.9
Short access day 10 total infusions0.10.10.20.3-0.30.3-0.3-0.30.30.30.20.3-0.30.40.30.10.1
Short access total infusions0.00.00.0-0.10.1-0.10.1-0.1-0.1-0.2-0.0-0.10.1-0.0-0.10.1-0.1
Short access day 1 locomotion0.80.91.60.8-0.80.8-0.8-1.10.8-1.1-1.20.8-0.80.90.81.3-1.2
Short access day 10 total locomotion3.53.84.72.1-2.12.1-2.1-2.12.1-0.4-1.72.1-2.12.22.11.8-1.8
Short access total locomotion0.70.71.10.8-0.80.8-0.8-1.00.8-0.5-0.90.8-0.80.90.81.0-1.0
Compulsive drug intake1.31.31.8-1.31.3-1.31.31.3-1.3-0.20.8-1.31.3-1.4-1.3-1.00.8
One hour access (0.3 mA shock)0.20.21.7-0.30.3-0.30.30.4-0.31.30.5-0.30.3-0.3-0.3-0.40.3
One hour access (shock baseline)0.40.43.20.6-0.50.5-0.5-0.40.51.80.20.6-0.50.60.50.10.0
Number of responses in last shaping day0.10.10.20.3-0.20.2-0.2-0.40.20.0-0.20.3-0.20.30.20.4-0.4
Context. condit. distance diff. score0.20.20.6-0.60.6-0.60.60.1-0.6-0.10.8-0.60.6-0.0-0.6-0.30.3
Locomotion velocity, session 10.50.51.60.5-0.50.5-0.5-0.60.5-0.8-1.30.5-0.50.30.51.1-1.2
Locomotion distance, session 10.50.73.6-0.10.1-0.10.1-0.8-0.1-0.8-1.4-0.20.10.3-0.11.7-1.9
Locomotion velocity, session 24.35.011.31.7-1.71.7-1.7-2.61.7-2.0-3.01.7-1.72.11.73.2-3.4
Locomotion distance, session 21.52.16.81.0-1.01.0-1.0-1.41.0-1.3-2.60.9-1.00.81.02.3-2.5
Locomotion velocity, session 36.67.69.92.9-2.92.9-2.9-3.12.9-1.0-2.52.9-2.93.12.92.8-2.7
Locomotion distance, session 30.10.10.8-0.00.0-0.00.0-0.2-0.00.90.3-0.00.00.3-0.0-0.00.0
Stereotopy head waving bouts, day 35.26.39.32.3-2.32.3-2.3-2.92.3-1.7-2.72.3-2.32.72.33.1-3.0
Stereotopy head waving duration, day 36.37.69.42.7-2.72.7-2.7-3.02.7-2.4-2.82.7-2.72.92.73.1-3.0
Locomotion velocity, session 70.60.71.80.7-0.70.7-0.7-1.20.7-0.5-0.40.7-0.71.40.71.0-1.0
Locomotion distance, session 70.20.21.0-0.20.2-0.20.20.2-0.20.71.0-0.20.20.0-0.2-0.70.7
Stereotopy head waving bouts, day 70.10.10.8-0.10.1-0.10.1-0.3-0.1-0.3-0.6-0.20.10.1-0.10.7-0.9
Stereotopy head waving duration, day 70.30.41.40.2-0.20.2-0.2-0.60.2-0.9-1.00.2-0.20.30.21.0-1.2
Locomotion velocity, session 80.91.03.90.4-0.40.4-0.4-1.20.4-1.0-1.60.4-0.41.00.41.9-2.0
Locomotion distance, session 80.30.41.50.2-0.20.2-0.2-0.80.2-1.0-0.80.2-0.20.60.21.1-1.2
Degree of sensitization distance0.30.30.4-0.70.7-0.70.70.5-0.7-0.30.6-0.70.7-0.5-0.7-0.50.5
Degree of sensitization stereotypy1.92.02.5-1.61.6-1.61.61.5-1.61.11.0-1.61.6-1.6-1.6-1.10.9
Condit. Reinf. active minus inactive responses4.55.16.42.3-2.32.3-2.3-2.52.3-1.2-2.22.2-2.32.52.32.4-2.4
Condit. Reinf. active-inactive response ratio2.12.33.01.7-1.71.7-1.7-1.51.7-0.6-1.11.7-1.71.51.71.1-1.0
Condit. Reinf. active responses3.94.88.52.0-2.02.0-2.0-2.42.0-1.1-2.72.0-2.02.22.02.8-2.9
Condit. Reinf. inactive responses1.01.24.30.7-0.70.7-0.7-1.10.7-0.6-1.80.7-0.70.80.71.8-2.1
Incentive salience index mean2.53.05.81.5-1.51.5-1.5-2.01.5-0.9-2.01.5-1.51.81.52.3-2.4
Condit. Reinf. lever presses0.30.42.0-0.30.3-0.30.3-0.2-0.3-0.4-1.1-0.30.3-0.2-0.31.1-1.4
Time in familiar zone, hab. session 12.42.32.81.7-1.71.7-1.7-1.51.7-1.1-1.11.7-1.71.51.71.1-1.0
Time in novel zone, hab. session 11.31.31.7-1.31.3-1.31.31.1-1.30.60.6-1.31.3-1.2-1.3-0.70.6
Total zone transitions, hab. session 11.01.43.80.8-0.80.8-0.8-1.30.8-0.6-1.90.8-0.81.00.81.9-2.0
Total locomotion distance, hab. session 11.31.86.40.7-0.70.7-0.7-1.60.7-0.4-2.20.7-0.71.20.72.4-2.5
Locomotion velocity, hab. session 11.72.57.41.0-1.01.0-1.0-1.91.0-0.6-2.41.0-1.01.51.02.6-2.7
Time in familiar zone, hab. session 26.26.47.92.8-2.82.8-2.8-2.52.8-1.9-1.92.8-2.82.62.82.0-1.7
Time in novel zone, hab. session 24.74.75.8-2.42.4-2.42.42.2-2.40.31.7-2.42.4-2.3-2.4-1.71.8
Total zone transitions, hab. session 20.50.72.3-0.70.7-0.70.70.2-0.7-1.5-1.0-0.80.7-0.6-0.70.9-0.8
Total locomotion distance, hab. session 21.31.85.20.8-0.80.8-0.8-1.30.8-2.3-2.00.8-0.80.90.82.0-1.8
Locomotion velocity, hab. session 21.41.96.90.7-0.70.7-0.7-1.30.7-2.6-2.20.7-0.70.80.72.2-2.0
Novel to familiar place preference ratio4.54.86.0-2.42.4-2.42.42.2-2.41.31.5-2.52.4-2.4-2.4-1.61.4
Novelty place preference2.82.93.8-1.91.9-1.91.91.7-1.90.71.1-1.91.9-1.9-1.9-1.11.0
Time in novel zone, NPP test3.13.24.2-2.02.0-2.02.01.8-2.00.81.3-2.02.0-1.9-2.0-1.31.2
Total zone transitions, NPP test0.20.21.0-0.20.2-0.20.2-0.0-0.2-0.5-1.0-0.30.2-0.3-0.20.8-0.9
Total locomotion distance, NPP test0.20.31.0-0.40.4-0.40.4-0.2-0.4-0.2-0.8-0.40.4-0.2-0.40.9-1.0
Locomotion velocity, NPP test0.20.31.5-0.10.1-0.10.1-0.4-0.1-0.5-1.1-0.20.10.0-0.11.1-1.2
Pavlov. Cond. lever latency0.20.31.20.3-0.30.3-0.30.50.3-0.10.50.3-0.3-0.30.3-1.01.1
Pavlov. Cond. magazine entry latency3.54.56.52.1-2.12.1-2.1-2.52.1-1.4-1.92.1-2.12.52.12.3-2.4
Pavlov. Cond. change in total contacts0.20.30.80.2-0.20.2-0.2-0.80.2-0.4-0.40.2-0.20.80.20.9-0.9
Pavlov. Cond. index score0.81.03.00.6-0.60.6-0.6-1.40.6-0.6-1.10.6-0.61.30.61.6-1.7
Pavlov. Cond. latency score0.81.03.60.5-0.50.5-0.5-1.40.5-0.7-1.20.5-0.51.20.51.8-1.9
Pavlov. Cond. lever contacts0.30.41.8-0.10.1-0.10.1-0.7-0.1-0.1-0.8-0.20.10.5-0.11.2-1.3
Pavlov. Cond. magazine entry number1.11.42.3-1.01.0-1.01.01.5-1.01.21.0-1.01.0-1.4-1.0-1.41.5
Pavlov. Cond. intertrial magazine entries0.20.30.40.6-0.60.6-0.6-0.20.60.50.00.6-0.60.30.6-0.20.3
Pavlov. Cond. lever-magazine prob. diff.1.11.43.60.9-0.90.9-0.9-1.60.9-0.8-1.30.9-0.91.50.91.8-1.9
Pavlov. Cond. response bias1.51.83.21.2-1.21.2-1.2-1.71.2-0.6-1.31.2-1.21.71.21.7-1.8
Bone: apparent density0.30.51.1-0.60.6-0.60.60.4-0.6-1.1-1.0-0.60.6-1.0-0.60.5-0.8
Bone surface0.71.26.4-0.20.2-0.20.2-0.3-0.2-2.5-2.0-0.30.2-0.5-0.21.4-1.8
Bone volume0.61.05.1-0.30.3-0.30.3-0.1-0.3-2.2-1.9-0.30.3-0.6-0.31.2-1.7
Bone: connectivity density0.40.61.2-0.80.8-0.80.80.6-0.8-0.9-0.3-0.90.8-1.1-0.8-0.0-0.3
Bone: cortical apparent density0.91.22.2-0.91.0-1.01.01.4-1.0-0.60.9-0.91.0-1.4-1.0-1.31.5
Bone: cortical area0.60.91.3-1.11.1-1.11.10.9-1.10.00.5-1.11.1-1.0-1.1-0.50.3
Bone: cortical porosity0.40.51.20.5-0.60.6-0.6-0.70.6-0.1-1.00.5-0.60.50.60.9-1.1
Bone: cortical porosity0.10.10.7-0.20.1-0.10.1-0.1-0.1-0.2-0.7-0.20.1-0.1-0.10.6-0.8
Bone: cortical thickness1.22.02.4-1.51.5-1.51.51.5-1.50.91.0-1.51.5-1.5-1.5-1.21.0
Bone: cortical thickness0.30.43.50.2-0.20.2-0.20.20.21.90.60.3-0.20.10.2-0.60.8
Bone: cortical tissue density0.60.81.8-0.70.8-0.80.81.2-0.8-0.70.7-0.70.8-1.2-0.8-1.21.3
Bone: elastic displacement0.10.10.40.5-0.40.4-0.4-0.10.4-0.2-0.60.5-0.40.00.40.2-0.2
Bone: elastic work0.30.40.8-0.70.6-0.60.60.8-0.60.30.5-0.70.6-0.9-0.6-0.70.7
Bone: endosteal estimation0.20.30.5-0.70.7-0.70.70.4-0.7-0.70.4-0.70.7-0.4-0.7-0.30.3
Bone: endosteal perimeter0.30.72.40.5-0.60.6-0.6-0.90.6-1.6-0.90.5-0.60.70.61.1-1.2
Bone: final force1.21.92.7-1.61.5-1.51.51.3-1.50.41.2-1.61.5-1.4-1.5-1.11.0
Bone: final moment0.91.52.1-1.51.4-1.41.41.2-1.40.31.0-1.41.4-1.3-1.4-1.01.0
Bone: marrow area0.20.40.6-0.70.7-0.70.70.4-0.7-0.70.5-0.70.7-0.4-0.7-0.30.3
Bone: maximum diameter0.71.32.90.8-0.80.8-0.8-1.20.8-1.7-1.50.8-0.81.00.81.6-1.7
Bone: maximum force1.22.02.6-1.61.5-1.51.51.4-1.50.61.4-1.61.5-1.3-1.5-1.21.2
Bone: maximum moment0.91.62.1-1.51.4-1.41.41.3-1.40.41.2-1.41.4-1.3-1.4-1.11.1
Bone: minimum diameter0.00.10.2-0.20.2-0.20.2-0.2-0.2-0.2-0.1-0.20.20.2-0.20.4-0.5
Bone: periosteal estimation0.30.71.0-1.01.0-1.01.00.6-1.0-0.70.3-1.01.0-0.7-1.0-0.20.2
Bone: periosteal perimeter0.10.21.0-0.0-0.10.1-0.1-0.40.1-1.0-0.5-0.0-0.10.20.10.7-0.9
Bone: post-yield work0.40.61.2-0.80.7-0.70.70.5-0.71.11.1-0.80.7-0.3-0.7-0.60.6
Bone: stiffness2.64.25.5-2.32.3-2.32.31.9-2.30.62.1-2.32.3-1.8-2.3-1.71.6
Bone: tissue strength1.71.72.2-1.41.4-1.41.41.4-1.40.31.0-1.41.4-1.5-1.4-1.21.1
Bone: trabecular number0.60.92.70.6-0.60.6-0.6-1.00.6-1.3-1.60.6-0.60.60.61.4-1.7
Bone: trabecular spacing0.81.04.5-0.10.1-0.10.10.7-0.12.11.8-0.10.1-0.1-0.1-1.51.9
Bone: trabecular thickness0.81.04.4-0.80.7-0.70.70.4-0.7-2.1-1.4-0.80.7-1.1-0.70.8-1.2
Bone: trabecular tissue density1.31.82.5-1.41.3-1.31.31.3-1.31.21.6-1.41.3-1.1-1.3-1.41.6
Breakpoint value in progressive ratio session5.25.86.82.6-2.52.5-2.5-2.52.5-1.2-2.12.6-2.52.62.52.2-2.1
Distance traveled before self-admin0.60.61.0-0.90.9-0.90.90.8-0.9-0.50.5-0.90.9-1.0-0.9-0.60.5
Distance traveled after self-admin0.50.51.00.6-0.60.6-0.6-0.70.6-1.0-0.90.6-0.60.60.60.9-0.9
Delta time in closed arm before/after self-admin1.11.13.6-0.40.4-0.40.40.8-0.41.91.8-0.40.4-0.4-0.4-1.61.9
Delta time in open arm before/after self-admin1.11.01.8-1.11.1-1.11.11.2-1.1-0.30.8-1.11.1-1.3-1.1-0.90.8
Diff in mean of infusions in LGA sessions2.12.32.41.5-1.51.5-1.5-1.51.5-1.6-1.51.5-1.51.51.51.4-1.5
Extinction: sum of active levers before priming1.11.11.51.2-1.11.1-1.1-1.11.10.2-0.61.2-1.11.21.10.7-0.8
Active lever presses in extinction session 62.12.02.71.4-1.41.4-1.4-1.41.4-1.3-1.61.4-1.41.21.41.5-1.6
Delta distance traveled before/after self-admin1.61.82.21.3-1.31.3-1.3-1.51.3-0.5-1.41.3-1.31.51.31.5-1.5
Delta ambulatory time before/after self-admin1.82.02.81.4-1.41.4-1.4-1.61.4-0.5-1.51.4-1.41.61.41.7-1.6
Time in closed arm before self-admin0.70.81.2-1.11.1-1.11.10.8-1.1-0.70.1-1.11.1-1.0-1.1-0.2-0.1
Time in closed arm after self-admin0.00.00.10.2-0.20.2-0.2-0.10.20.1-0.00.2-0.20.20.20.1-0.0
Time in open arm before self-admin0.60.71.00.9-0.90.9-0.9-0.90.90.5-0.60.9-0.91.00.90.7-0.4
Time in open arm after self-admin0.70.81.1-0.90.8-0.80.81.0-0.80.51.0-0.90.8-1.0-0.8-1.01.1
Sum of active levers in priming session hrs 5-60.00.00.1-0.10.1-0.10.10.0-0.1-0.2-0.1-0.10.1-0.1-0.10.0-0.1
Time to tail flick, vehicle, before self-admin0.60.62.80.5-0.50.5-0.5-0.50.5-1.7-1.10.5-0.50.30.50.9-1.1
Time to tail flick, vehicle, after self-admin0.50.52.30.7-0.70.7-0.7-0.50.71.50.20.7-0.70.70.70.00.1
Time to tail flick, test, before self-admin0.20.20.70.2-0.20.2-0.2-0.40.2-0.3-0.80.2-0.20.20.20.7-0.8
Time to tail flick, test, after self-admin0.50.50.70.6-0.70.7-0.7-0.70.7-0.7-0.80.6-0.70.70.70.9-0.8
Delta time to tail flick, vehicle, before/after SA0.60.64.1-0.20.2-0.20.20.3-0.22.01.3-0.20.20.0-0.2-0.91.1
Delta time to tail flick, test, before/after SA0.30.30.50.6-0.60.6-0.6-0.50.6-0.3-0.00.6-0.60.70.60.2-0.2
Ambulatory time before self-admin0.60.61.0-0.80.8-0.80.80.9-0.8-0.50.5-0.80.8-1.0-0.8-0.70.6
Ambulatory time after self-admin0.20.20.50.4-0.40.4-0.4-0.50.4-0.6-0.70.4-0.40.40.40.7-0.7
Total heroin consumption1.92.22.41.5-1.51.5-1.5-1.51.5-0.9-1.61.5-1.51.41.51.5-1.5
Area under the delay curve2.22.32.9-1.61.5-1.51.51.6-1.50.51.6-1.61.5-1.6-1.5-1.51.7
Delay disc. indifference point, 0s delay6.97.510.2-3.13.0-3.03.02.8-3.01.01.7-3.23.0-3.2-3.0-1.91.7
Delay disc. indifference point, 16s delay0.20.20.3-0.30.4-0.40.40.4-0.4-0.50.3-0.30.4-0.4-0.4-0.40.6
Delay disc. indifference point, 2s delay5.46.07.3-2.72.6-2.62.62.5-2.61.42.1-2.72.6-2.6-2.6-2.12.1
Delay disc. indifference point, 24s delay1.01.01.7-0.91.0-1.01.01.1-1.00.41.1-0.91.0-1.0-1.0-1.21.3
Delay disc. indifference point, 4s delay0.80.81.1-1.01.0-1.01.01.0-1.00.00.8-1.01.0-1.0-1.0-0.80.8
Delay disc. indifference point, 8s delay1.21.32.6-1.10.9-0.90.91.1-0.90.91.6-1.10.9-1.0-0.9-1.41.6
Delay discount exponential model param2.12.22.81.5-1.51.5-1.5-1.51.5-0.5-1.61.5-1.51.51.51.5-1.7
Delay discount hyperbolic model param2.83.03.51.8-1.81.8-1.8-1.81.8-0.8-1.81.8-1.81.81.81.7-1.9
Fecal boli incidents, locomotor time 12.12.32.8-1.51.7-1.71.71.3-1.71.21.6-1.51.7-1.2-1.7-1.31.4
Change in fecal boli incidents, locomotor task0.10.10.30.1-0.10.1-0.1-0.40.1-0.6-0.40.1-0.10.40.10.4-0.4
Time >=10cm from walls, locomotor time 11.01.01.4-1.11.2-1.21.20.9-1.2-0.80.4-1.11.2-1.2-1.2-0.50.4
Bouts of movement, locomotor time 10.30.30.90.5-0.50.5-0.5-0.80.5-0.6-0.20.5-0.50.90.50.6-0.3
Total resting periods, locomotor time 10.30.40.90.5-0.50.5-0.5-0.90.5-0.9-0.40.5-0.50.90.50.7-0.5
Rest time, locomotor task time 10.50.61.40.5-0.40.4-0.4-1.20.4-1.1-0.70.5-0.41.20.41.2-1.0
Distance moved, locomotor task time 11.01.02.1-1.11.1-1.11.11.2-1.1-0.20.3-1.11.1-1.5-1.1-0.80.6
Vertical activity count, locomotor time 10.50.51.7-0.30.3-0.30.31.1-0.30.40.9-0.30.3-1.0-0.3-1.31.2
Time >=10cm from walls, locomotor time 21.61.72.8-1.31.2-1.21.21.4-1.20.71.7-1.31.2-1.2-1.2-1.51.6
Bouts of movement, locomotor time 20.90.94.60.6-0.70.7-0.7-0.70.7-2.1-1.30.6-0.70.50.71.2-1.1
Total resting periods, locomotor time 20.80.94.40.5-0.70.7-0.7-0.70.7-2.1-1.30.5-0.70.40.71.1-1.1
Rest time, locomotor task time 20.80.94.30.7-0.70.7-0.7-0.90.7-2.1-1.10.7-0.70.80.71.2-1.0
Distance moved, locomotor task time 20.80.93.2-0.80.8-0.80.80.9-0.81.81.1-0.80.8-0.8-0.8-1.10.9
Vertical activity count, locomotor time 21.01.14.5-0.70.7-0.70.70.9-0.72.11.5-0.70.7-0.8-0.7-1.31.2
Weight adjusted by age0.50.61.7-0.40.5-0.50.50.8-0.50.91.2-0.40.5-0.5-0.5-1.21.3
Seeking ratio, delayed vs. immediate footshock4.14.75.82.1-2.12.1-2.1-2.32.1-1.8-2.42.1-2.12.12.12.4-2.2
Locomotion in novel chamber0.20.20.40.5-0.50.5-0.5-0.30.5-0.6-0.30.5-0.50.50.50.20.2
Locomotion in novel chamber post-restriction1.01.22.11.1-1.11.1-1.1-1.31.1-0.2-0.71.1-1.11.51.11.0-0.8
Progressive ratio0.10.10.2-0.30.3-0.30.30.1-0.3-0.10.4-0.30.3-0.1-0.3-0.20.2
Food seeking constrained by brief footshock0.50.61.60.4-0.40.4-0.4-1.10.4-1.0-0.90.4-0.41.00.41.3-1.1
Seeking ratio, punishment vs. effort0.20.30.70.4-0.30.3-0.3-0.70.3-0.5-0.80.4-0.30.50.30.9-0.8
Run reversals in cocaine runway, females0.40.40.70.6-0.60.6-0.6-0.80.6-0.6-0.70.6-0.60.80.60.9-0.7
Run reversals in cocaine runway, males1.61.62.21.2-1.21.2-1.2-1.41.2-0.9-1.51.2-1.21.21.21.4-1.4
Latency to leave start box in cocaine runway0.40.42.00.5-0.50.5-0.5-0.30.50.2-1.40.5-0.50.00.50.8-1.1
Latency to leave start box in cocaine runway, F0.40.51.2-0.70.7-0.70.70.7-0.70.9-0.7-0.70.7-1.1-0.70.1-0.4
Latency to leave start box in cocaine runway, M2.82.63.51.9-1.91.9-1.9-1.61.90.0-1.01.9-1.91.81.91.1-1.1
Cd content in liver0.50.53.4-0.50.5-0.50.50.7-0.51.80.3-0.50.5-0.7-0.5-0.60.5
Co content in liver0.60.70.90.8-0.90.9-0.9-0.90.90.9-0.70.8-0.90.90.90.8-0.9
Cu content in liver0.20.20.4-0.60.6-0.60.60.2-0.6-0.2-0.2-0.60.6-0.4-0.60.2-0.3
Fe content in liver0.30.32.50.3-0.30.3-0.3-0.60.31.60.10.3-0.30.80.30.4-0.6
K content in liver0.30.31.2-0.40.3-0.30.3-0.4-0.30.3-0.6-0.40.30.3-0.30.9-1.1
Mg content in liver0.20.20.8-0.40.4-0.40.4-0.2-0.40.2-0.6-0.40.40.1-0.40.7-0.9
Mn content in liver1.31.55.50.5-0.50.5-0.5-1.40.5-1.6-1.90.4-0.51.00.52.1-2.3
Na content in liver0.91.01.5-1.21.2-1.21.20.5-1.20.70.3-1.21.2-0.7-1.20.0-0.4
Rb content in liver0.50.61.0-1.00.9-0.90.90.5-0.9-0.4-0.0-1.00.9-0.8-0.9-0.0-0.1
Se content in liver0.40.41.20.4-0.40.4-0.4-1.10.40.2-0.60.4-0.41.00.41.1-1.1
Sr content in liver0.10.10.20.3-0.30.3-0.30.00.30.30.40.3-0.30.20.3-0.40.4
Zn content in liver1.92.13.21.8-1.81.8-1.8-1.21.80.5-0.51.8-1.81.51.80.5-0.3