Hub : Genes

Cacng3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000012362 0.27 0.11 2.0e-09 0.04 0.09 0.08 0.09 4.1e-03 9.8e-06 6.4e-05 1.0e-05
2 Brain gene expression ENSRNOG00000012362 0.4 0.12 0.0e+00 0.22 0.25 0.26 0.23 6.1e-20 1.1e-22 6.2e-24 1.3e-21
3 Brain mRNA stability ENSRNOG00000012362 0.09 0.04 1.4e-08 0.09 0.08 0.07 0.07 2.8e-08 9.2e-08 5.4e-07 3.0e-07
4 IL gene expression ENSRNOG00000012362 0.34 0.15 5.2e-05 0.15 0.14 0.12 0.1 1.6e-04 2.4e-04 7.9e-04 1.9e-03
5 IL mRNA stability ENSRNOG00000012362 0.29 0.14 4.3e-04 0.1 0.09 0.1 0.08 2.3e-03 3.0e-03 2.6e-03 5.8e-03
6 NAcc gene expression ENSRNOG00000012362 0.2 0.09 1.2e-10 0.11 0.13 0.12 0.11 2.3e-08 6.1e-10 2.0e-09 9.7e-09
7 OFC mRNA stability ENSRNOG00000012362 0.58 0.14 5.2e-11 0.36 0.34 0.37 0.39 2.0e-09 7.1e-09 1.3e-09 3.6e-10
8 PL gene expression ENSRNOG00000012362 0.12 0.06 3.4e-09 0.1 0.1 0.09 0.08 7.7e-08 5.9e-08 4.3e-07 6.6e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.51.62.8-1.1-0.90.9-1.21.5-1.31.7-1.3
BMI without tail1.63.45.0-1.9-1.71.4-1.91.3-2.21.9-2.2
Body weight0.93.97.9-2.4-1.40.8-2.11.1-2.41.8-2.8
Epididymis fat weight0.10.20.50.30.2-0.70.6-0.40.2-0.3-0.0
Glucose0.50.72.20.4-0.21.4-0.51.50.21.00.2
Heart weight2.02.96.32.22.5-0.61.80.52.1-0.31.9
Left kidney weight0.92.58.0-1.80.00.1-1.51.0-1.81.5-2.8
Right kidney weight0.92.67.9-1.8-0.4-0.1-1.51.1-1.81.6-2.8
Tail length0.72.14.2-1.6-1.21.3-1.60.6-1.61.2-2.1
Length with tail0.41.54.4-1.6-0.80.3-1.4-0.1-1.50.5-2.1
Length without tail0.20.30.9-0.9-0.1-0.5-0.5-0.3-0.6-0.1-0.9
Liver weight, left0.50.81.61.30.81.20.31.01.00.60.5
Liver weight, right0.30.61.4-0.0-1.01.2-0.41.0-0.20.9-0.4
Parametrial fat weight0.61.33.4-0.1-0.21.4-1.11.8-0.41.6-0.9
Retroperitoneal fat weight0.62.14.42.11.8-0.51.7-0.11.9-0.71.4
Intraocular pressure0.00.00.00.00.00.1-0.10.10.10.10.1
Extensor digitorum longus weight3.112.522.1-4.3-3.71.9-3.81.5-4.12.8-4.7
Soleus weight1.33.95.9-1.5-1.62.4-2.02.0-1.82.3-2.0
Tibialis anterior weight5.318.428.0-4.7-3.93.1-4.83.0-4.84.2-5.3
Tibia length0.00.10.20.10.2-0.30.00.40.10.40.1
Number of licking bursts5.05.910.42.72.2-1.52.6-1.72.7-2.23.2
Food consumed during 24 hour testing period2.42.93.7-1.6-1.91.7-1.81.6-1.81.9-1.4
Times rat made contact with spout1.41.63.0-1.7-1.70.3-1.20.7-1.71.0-1.1
Mean time between licks in bursts0.20.30.80.7-0.6-0.10.3-0.20.6-0.40.9
Mean num. licks in bursts7.18.511.9-3.4-3.01.6-3.12.1-3.42.7-3.5
Std. dev. time between licks in bursts0.20.20.50.5-0.40.7-0.30.20.40.10.5
Water consumed over 24 hours0.40.51.4-0.40.0-1.20.7-1.1-0.1-0.80.2
Indifference point 0 sec1.32.13.7-0.8-1.91.6-1.41.7-1.01.8-0.9
Indifference point AUC0.80.93.20.50.31.3-0.51.80.31.30.1
Indifference point function ln k0.71.12.2-1.5-1.2-0.0-0.8-0.2-1.40.4-1.4
Indifference point function log k0.71.12.2-1.5-1.2-0.0-0.8-0.2-1.40.4-1.4
Delay discounting total patch changes 0 sec1.11.93.3-0.5-1.81.7-1.21.7-0.81.7-0.7
Delay discounting total patch changes 12 sec0.40.51.60.0-0.60.8-0.51.3-0.11.00.2
Delay discounting total patch changes 18 sec0.20.30.50.7-0.60.50.20.40.60.20.7
Delay discounting total patch changes 24 sec0.70.82.30.4-1.01.5-0.41.30.11.10.3
Delay discounting total patch changes 6 sec1.52.36.20.5-1.22.5-1.02.40.12.00.2
Delay discounting time to switch 0 sec1.62.55.70.50.4-2.41.9-2.20.8-2.11.0
Delay discounting water rate 0 sec0.40.61.4-0.4-0.21.0-0.81.2-0.51.2-0.4
Delay discounting water rate 12 sec0.10.20.90.20.90.6-0.30.00.10.1-0.0
Delay discounting water rate 18 sec0.10.20.60.40.80.7-0.10.00.30.1-0.3
Delay discounting water rate 24 sec0.00.00.2-0.00.00.4-0.10.1-0.20.3-0.1
Delay discounting water rate 6 sec0.50.72.20.80.21.5-0.11.20.50.80.7
Locomotor activity0.30.51.3-0.7-1.10.7-0.90.3-0.50.5-0.9
Locomotor testing distance0.10.20.40.2-0.60.5-0.00.60.20.50.0
Locomotor testing rearing0.81.32.71.60.8-0.01.3-0.11.5-0.51.7
Light reinforcement 10.40.71.20.71.1-0.90.7-0.90.9-0.90.4
Light reinforcement 20.10.10.40.0-0.60.5-0.40.2-0.00.1-0.2
Reaction time number correct1.31.82.41.31.5-0.81.3-1.21.5-1.51.4
Reaction time mean minus median0.00.00.1-0.10.30.2-0.20.2-0.10.2-0.2
Reaction time mean minus median AUC0.10.10.30.30.50.3-0.10.20.30.00.2
Reaction time num false alarms0.10.10.30.5-0.10.20.4-0.20.4-0.20.6
Reaction time num false alarms AUC0.00.00.10.2-0.30.00.1-0.20.0-0.10.0
Reaction time trials correct on left1.31.82.41.31.5-0.81.3-1.21.5-1.51.4
Reaction time trials on left1.31.82.41.31.5-0.81.3-1.31.5-1.61.3
Reaction time mean0.20.30.7-0.7-0.20.1-0.80.4-0.60.5-0.8
Reaction time mean AUC0.20.30.8-0.80.00.0-0.70.4-0.60.4-0.9
Median of all reaction times0.40.61.1-0.9-0.60.3-0.90.5-0.90.6-1.1
Reaction time omissions0.40.61.6-0.70.0-1.1-0.0-1.2-0.3-0.9-0.7
Reaction time false alarm rate0.20.31.0-0.4-1.00.3-0.30.2-0.60.5-0.4
Reaction time premature initiation rate0.81.12.8-1.20.2-1.3-0.0-1.7-0.7-1.1-1.2
Reaction time premature initiations1.42.05.9-0.51.1-1.90.7-2.40.1-2.0-0.5
Std. dev. reaction times0.00.00.10.00.3-0.10.00.10.10.0-0.2
Reaction time trials completed1.31.82.41.31.5-0.81.3-1.31.5-1.61.3
Reaction time trials AUC1.11.62.11.21.4-0.71.2-1.21.4-1.51.2
Social response proportion0.70.81.31.10.7-0.61.0-0.41.1-0.71.1
Social responses0.70.91.91.11.4-0.71.0-0.51.1-0.71.0
Social time0.91.22.71.60.8-0.31.1-0.21.6-0.51.4
Conditioned locomotion0.30.30.9-0.70.2-0.60.2-1.0-0.5-0.5-0.6
Cocaine response after cond. corrected1.21.32.31.50.6-0.61.5-0.71.4-0.91.5
Cocaine response after cond. not corrected0.30.30.60.70.1-0.40.8-0.30.7-0.40.5
Cocaine response before conditioning1.51.94.4-1.7-1.10.4-1.50.8-1.51.2-2.1
Saline control response0.81.02.70.2-1.11.6-0.71.60.01.20.3
Condit. Reinf. active minus inactive responses1.41.84.7-0.3-0.92.2-1.42.0-0.61.6-0.1
Condit. Reinf. active-inactive response ratio1.41.54.30.5-0.62.1-0.82.00.01.40.8
Condit. Reinf. active responses0.91.32.2-0.7-1.11.5-1.41.3-0.91.2-0.5
Condit. Reinf. inactive responses0.70.81.9-1.3-0.9-0.5-0.7-0.5-1.1-0.1-1.4
Condit. Reinf. lever presses1.82.43.7-1.3-1.91.8-1.81.3-1.41.5-1.3
Condit. Reinf. lever reinforcers received0.60.82.0-0.4-0.91.4-1.11.1-0.50.9-0.2
Pavlov. Cond. lever latency0.30.51.00.60.8-1.00.9-0.30.6-0.50.6
Pavlov. Cond. magazine entry latency3.03.54.31.71.9-1.62.1-1.82.0-2.01.8
Pavlov. Cond. change in total contacts0.30.41.00.60.21.0-0.40.80.50.40.6
Pavlov. Cond. index score0.50.61.00.90.7-0.20.7-0.61.0-0.81.0
Pavlov. Cond. latency score0.40.50.80.80.8-0.20.7-0.60.9-0.80.8
Pavlov. Cond. lever contacts0.60.82.1-0.6-0.91.4-1.20.6-0.70.8-0.9
Pavlov. Cond. magazine entry number2.02.53.3-1.6-1.71.2-1.61.2-1.71.6-1.8
Pavlov. Cond. intertrial magazine entries2.32.94.6-2.0-1.51.3-1.81.1-2.01.6-2.2
Pavlov. Cond. lever-magazine prob. diff.0.60.71.11.00.8-0.40.8-0.81.0-0.91.1
Pavlov. Cond. response bias0.10.10.20.40.10.40.0-0.20.4-0.30.4
Conditioned reinforcement - actives0.10.10.3-0.2-0.50.40.10.4-0.20.6-0.1
Conditioned reinforcement - inactives0.70.82.1-0.1-1.41.3-0.41.1-0.31.00.1
Conditioned locomotion0.50.61.6-0.10.2-1.30.9-1.10.1-0.80.2
Intermittent access intake day 1-15 change0.30.30.90.6-1.00.50.20.20.40.10.7
Intermittent access intake escalation0.30.30.80.8-0.50.30.40.10.6-0.10.9
Intermittent access intake escalation 21.11.12.41.50.2-0.31.1-0.61.5-0.81.5
Intermitt. access day 1 inactive lever presses0.30.31.00.8-0.20.10.70.20.60.11.0
Intermitt. access day 15 inactive lever presses1.11.22.4-1.5-1.50.1-0.80.3-1.50.6-1.3
Intermitt. access escalation Index0.40.30.8-0.5-0.10.8-0.90.3-0.40.4-0.6
Intermittent access day 1 total infusions1.92.13.5-0.8-1.91.9-1.11.7-1.11.8-0.9
Intermittent access day 15 total infusions0.60.61.40.4-1.11.2-0.01.00.10.90.4
Intermittent access terminal intake (last 3 days)1.31.43.60.1-1.81.9-0.61.4-0.31.30.1
Intermittent access total infusions2.72.95.4-1.0-2.32.2-1.51.9-1.22.0-1.1
Intermittent access day 1 locomotion1.71.73.7-0.5-1.31.6-0.91.9-0.91.8-0.5
Intermittent access day 15 total locomotion1.21.32.61.3-0.51.60.31.50.81.11.2
Intermittent access total locomotion2.52.85.9-0.5-1.62.3-1.32.4-0.92.3-0.6
Intermittent access standard deviation0.70.81.91.40.10.20.80.71.20.31.2
Cocaine induced anxiety0.10.10.30.3-0.00.10.40.50.30.10.4
Post-drug Anxiety0.40.51.40.91.20.50.30.50.9-0.10.5
Baseline Anxiety0.10.10.3-0.00.20.6-0.6-0.1-0.00.0-0.5
Lifetime Intake2.12.44.4-1.0-2.11.9-1.31.6-1.21.7-1.0
Incentive Sensitization - Responses0.30.31.5-0.6-1.2-0.30.1-0.3-0.60.1-0.3
Incentive Sensitization - Breakpoint0.50.51.9-0.8-1.4-0.1-0.2-0.1-0.80.3-0.6
Progressive ratio test 1 active lever presses1.41.43.0-0.6-1.01.5-1.01.7-0.81.6-0.6
Progressive ratio test 1 breakpoint1.61.63.4-0.6-1.01.7-1.11.8-0.91.7-0.6
Progressive ratio test 1 inactive lever presses1.51.63.2-1.4-1.80.6-1.01.1-1.51.2-1.1
Progressive ratio test 2 active lever presses0.20.20.4-0.1-0.70.50.10.5-0.20.60.2
Progressive ratio test 2 breakpoint0.30.30.7-0.3-0.60.6-0.30.7-0.50.8-0.1
Progressive ratio test 2 inactive lever presses0.20.20.9-0.2-1.00.5-0.20.3-0.20.3-0.3
Total sessions with >9 infusions1.82.04.5-1.6-2.11.1-1.20.7-1.71.1-1.3
Short access day 1 total inactive lever presses0.30.30.8-0.5-0.4-0.7-0.2-0.9-0.1-0.6-0.8
Short access day 10 total inactive lever presses0.20.20.40.50.1-0.20.60.00.6-0.30.6
Short access day 1 total infusions0.10.10.3-0.4-0.50.00.1-0.4-0.3-0.1-0.2
Short access day 10 total infusions1.41.54.9-1.0-2.21.0-0.61.0-1.31.3-0.5
Short access total infusions1.41.62.6-1.0-1.61.4-1.11.2-1.21.4-1.0
Short access day 1 locomotion0.50.52.1-0.8-1.40.2-0.3-0.2-0.90.2-0.3
Short access day 10 total locomotion1.71.83.9-0.9-2.01.2-0.81.7-1.21.8-0.5
Short access total locomotion2.82.95.6-0.7-1.92.2-1.22.4-1.12.3-0.7
Compulsive drug intake0.20.20.40.20.6-0.70.2-0.60.2-0.50.0
One hour access (0.3 mA shock)0.91.12.90.6-0.91.7-0.21.50.21.40.6
One hour access (shock baseline)0.80.92.20.9-0.41.40.11.50.61.00.9
Number of responses in last shaping day0.60.61.9-0.8-1.40.5-0.60.1-0.80.4-0.8
Context. condit. distance diff. score1.92.33.01.51.7-1.31.6-1.31.6-1.51.6
Locomotion velocity, session 10.40.41.2-0.6-1.10.4-0.80.4-0.70.5-0.5
Locomotion distance, session 10.00.00.10.0-0.30.1-0.20.3-0.10.20.1
Locomotion velocity, session 20.10.10.4-0.2-0.60.1-0.10.1-0.30.2-0.1
Locomotion distance, session 20.40.51.1-0.7-1.00.7-0.70.4-0.90.6-0.6
Locomotion velocity, session 30.70.82.2-1.2-0.20.4-1.00.2-1.10.7-1.5
Locomotion distance, session 30.60.61.5-1.2-0.60.2-0.80.0-1.10.4-1.1
Stereotopy head waving bouts, day 31.21.54.2-0.5-0.92.0-1.51.4-0.71.3-0.5
Stereotopy head waving duration, day 31.11.33.4-0.6-1.01.8-1.41.2-0.81.2-0.8
Locomotion velocity, session 71.11.23.5-0.8-0.3-1.70.4-1.9-0.5-1.3-0.6
Locomotion distance, session 71.21.54.20.50.3-1.41.1-2.00.6-1.80.8
Stereotopy head waving bouts, day 70.50.51.0-0.9-0.10.5-0.80.4-0.90.6-1.0
Stereotopy head waving duration, day 70.91.12.0-1.4-0.40.6-1.10.7-1.31.0-1.4
Locomotion velocity, session 80.10.10.2-0.20.10.3-0.40.3-0.20.3-0.3
Locomotion distance, session 80.20.30.50.40.5-0.70.7-0.70.4-0.70.6
Degree of sensitization distance2.32.34.22.01.0-0.61.6-1.01.8-1.42.0
Degree of sensitization stereotypy0.40.41.1-1.00.1-0.3-0.4-0.1-0.90.3-1.0
Condit. Reinf. active minus inactive responses0.00.00.1-0.1-0.2-0.30.2-0.30.0-0.20.2
Condit. Reinf. active-inactive response ratio0.10.10.3-0.3-0.6-0.1-0.0-0.2-0.1-0.1-0.2
Condit. Reinf. active responses0.10.10.20.1-0.20.4-0.00.40.00.30.5
Condit. Reinf. inactive responses0.20.30.80.60.30.40.10.70.30.30.9
Incentive salience index mean0.30.40.9-0.9-0.9-0.2-0.4-0.1-0.80.2-0.7
Condit. Reinf. lever presses0.71.01.8-1.4-1.40.1-0.90.2-1.30.6-1.2
Time in familiar zone, hab. session 11.11.02.31.51.10.50.70.91.20.31.4
Time in novel zone, hab. session 12.12.04.4-1.8-0.9-1.4-0.4-2.1-1.3-1.2-1.6
Total zone transitions, hab. session 10.91.32.4-0.6-0.31.5-1.21.6-0.81.5-0.9
Total locomotion distance, hab. session 11.42.13.1-1.5-1.01.1-1.51.2-1.71.5-1.8
Locomotion velocity, hab. session 11.21.82.5-1.2-0.91.2-1.31.4-1.41.6-1.4
Time in familiar zone, hab. session 21.21.22.5-0.3-1.31.5-0.81.6-0.51.4-0.1
Time in novel zone, hab. session 21.41.52.50.61.5-1.61.0-1.60.8-1.50.5
Total zone transitions, hab. session 21.11.42.3-0.9-0.51.3-1.21.5-1.01.5-1.1
Total locomotion distance, hab. session 20.91.21.8-1.2-0.90.7-1.11.0-1.31.2-1.3
Locomotion velocity, hab. session 21.72.33.2-1.7-1.30.9-1.51.3-1.81.6-1.8
Novel to familiar place preference ratio0.20.20.70.40.3-0.20.4-0.30.4-0.30.8
Novelty place preference0.20.20.70.50.2-0.10.4-0.20.4-0.30.9
Time in novel zone, NPP test0.30.31.20.70.3-0.10.5-0.30.6-0.41.1
Total zone transitions, NPP test0.50.71.2-0.70.10.7-0.91.0-0.71.0-1.1
Total locomotion distance, NPP test0.10.10.3-0.30.1-0.2-0.20.1-0.40.2-0.5
Locomotion velocity, NPP test0.10.20.6-0.50.3-0.2-0.30.1-0.50.2-0.8
Pavlov. Cond. lever latency1.31.73.21.81.2-0.21.3-0.41.7-0.91.8
Pavlov. Cond. magazine entry latency0.30.40.8-0.90.1-0.90.0-0.8-0.7-0.3-0.8
Pavlov. Cond. change in total contacts1.21.22.8-1.7-1.1-0.9-0.6-0.8-1.3-0.2-1.5
Pavlov. Cond. index score0.40.61.4-1.2-0.5-0.5-0.4-0.4-1.10.1-1.1
Pavlov. Cond. latency score0.50.71.6-1.3-0.5-0.2-0.7-0.1-1.10.4-1.3
Pavlov. Cond. lever contacts1.11.32.9-1.7-1.1-0.3-1.0-0.0-1.60.5-1.6
Pavlov. Cond. magazine entry number0.40.51.30.8-0.21.1-0.31.10.50.60.5
Pavlov. Cond. intertrial magazine entries0.60.71.41.20.60.90.10.81.00.21.2
Pavlov. Cond. lever-magazine prob. diff.0.60.82.0-1.4-0.7-0.3-0.6-0.2-1.30.3-1.2
Pavlov. Cond. response bias0.50.61.6-0.9-0.2-1.20.2-1.1-0.7-0.6-0.7
Bone: apparent density0.81.32.3-0.8-0.81.4-1.21.5-0.91.5-0.9
Bone surface1.62.83.7-1.8-1.51.3-1.91.4-1.81.6-1.8
Bone volume1.62.73.3-1.6-1.51.6-1.81.5-1.71.7-1.6
Bone: connectivity density0.40.71.1-0.7-0.70.9-0.91.1-0.71.0-0.6
Bone: cortical apparent density0.20.30.90.7-0.2-0.10.50.50.60.11.0
Bone: cortical area2.13.14.3-1.5-1.51.9-1.91.8-1.62.1-1.9
Bone: cortical porosity1.01.13.7-1.40.10.2-1.0-0.2-1.20.3-1.9
Bone: cortical porosity1.01.03.5-1.50.00.0-0.9-0.4-1.30.1-1.9
Bone: cortical thickness1.11.82.8-0.8-1.41.6-1.21.7-1.01.7-1.1
Bone: cortical thickness0.10.20.50.3-0.20.7-0.20.70.20.50.0
Bone: cortical tissue density0.20.30.90.7-0.2-0.20.50.40.60.00.9
Bone: elastic displacement0.10.10.60.20.30.8-0.20.50.20.3-0.1
Bone: elastic work1.62.03.3-1.1-1.51.8-1.61.5-1.21.5-1.1
Bone: endosteal estimation0.71.52.4-1.4-0.71.1-1.50.8-1.41.2-1.5
Bone: endosteal perimeter0.30.61.5-1.2-0.40.1-0.9-0.1-1.00.3-1.2
Bone: final force5.99.712.4-2.8-2.73.3-3.53.1-3.03.5-2.9
Bone: final moment5.38.711.1-2.5-2.53.3-3.33.0-2.83.3-2.7
Bone: marrow area0.71.52.3-1.4-0.71.0-1.50.7-1.41.1-1.5
Bone: maximum diameter1.22.23.0-1.4-0.81.6-1.71.4-1.41.7-1.7
Bone: maximum force4.98.510.8-2.6-2.73.0-3.32.8-2.93.2-2.8
Bone: maximum moment4.27.39.3-2.4-2.42.9-3.02.7-2.63.0-2.5
Bone: minimum diameter1.22.22.8-1.6-1.61.1-1.71.0-1.61.4-1.7
Bone: periosteal estimation1.93.95.0-1.9-1.51.9-2.21.7-2.02.1-2.2
Bone: periosteal perimeter0.40.71.8-1.0-0.30.6-0.90.4-0.90.7-1.3
Bone: post-yield work1.62.24.6-1.7-1.00.9-1.70.7-1.71.4-2.1
Bone: stiffness4.46.99.0-2.3-2.22.6-3.02.7-2.53.0-2.7
Bone: tissue strength0.50.50.9-1.0-0.30.3-0.80.1-0.90.4-0.9
Bone: trabecular number0.40.71.6-0.3-0.21.2-0.71.3-0.41.1-0.5
Bone: trabecular spacing0.81.03.00.00.2-1.50.7-1.70.3-1.40.1
Bone: trabecular thickness0.91.13.30.1-0.11.8-0.71.7-0.11.4-0.2
Bone: trabecular tissue density0.20.20.4-0.30.10.4-0.70.7-0.20.5-0.6
Breakpoint value in progressive ratio session0.40.41.50.5-0.71.2-0.50.50.30.30.3
Distance traveled before self-admin0.40.40.8-0.7-0.90.5-0.90.2-0.90.4-0.3
Distance traveled after self-admin1.92.15.1-1.7-2.30.8-1.60.1-1.90.7-1.1
Delta time in closed arm before/after self-admin2.42.36.60.30.8-2.61.5-2.10.7-2.00.6
Delta time in open arm before/after self-admin7.77.416.1-1.0-2.14.0-2.83.6-1.73.5-1.3
Diff in mean of infusions in LGA sessions0.60.71.41.10.11.20.11.00.70.51.1
Extinction: sum of active levers before priming0.20.20.90.2-0.90.6-0.10.40.10.30.4
Active lever presses in extinction session 60.40.41.30.1-0.30.9-0.71.10.00.8-0.2
Delta distance traveled before/after self-admin0.40.41.1-0.8-1.1-0.2-0.4-0.5-0.8-0.2-0.5
Delta ambulatory time before/after self-admin0.50.51.3-1.0-1.10.1-0.60.1-0.90.3-0.6
Time in closed arm before self-admin0.80.91.81.30.6-0.11.4-0.41.1-0.41.4
Time in closed arm after self-admin7.17.410.72.72.5-2.53.3-2.52.9-2.82.5
Time in open arm before self-admin0.40.40.8-0.30.3-0.9-0.5-0.80.1-0.9-0.7
Time in open arm after self-admin8.39.113.6-2.3-3.33.5-3.73.0-2.63.2-2.4
Sum of active levers in priming session hrs 5-61.31.33.0-1.4-0.70.5-1.70.5-1.20.6-1.7
Time to tail flick, vehicle, before self-admin0.10.10.20.2-0.20.4-0.30.10.3-0.0-0.1
Time to tail flick, vehicle, after self-admin1.11.14.71.12.2-0.50.6-0.51.1-0.80.8
Time to tail flick, test, before self-admin0.80.81.4-1.2-1.10.2-1.0-0.0-1.00.3-1.1
Time to tail flick, test, after self-admin1.91.93.61.11.1-1.71.9-1.21.2-1.21.4
Delta time to tail flick, vehicle, before/after SA0.10.10.60.10.8-0.0-0.00.3-0.00.10.1
Delta time to tail flick, test, before/after SA1.21.12.41.01.4-1.01.5-0.40.9-0.51.2
Ambulatory time before self-admin0.20.20.6-0.3-0.50.6-0.80.1-0.50.2-0.0
Ambulatory time after self-admin1.92.16.0-1.7-2.40.7-1.6-0.1-1.80.4-1.1
Total heroin consumption0.40.41.50.2-0.91.2-0.60.70.10.60.0
Area under the delay curve0.10.10.20.50.0-0.10.3-0.20.5-0.10.3
Delay disc. indifference point, 0s delay0.00.00.1-0.2-0.0-0.3-0.10.1-0.20.3-0.2
Delay disc. indifference point, 16s delay3.43.56.12.51.8-0.81.8-1.32.5-1.71.9
Delay disc. indifference point, 2s delay4.55.06.8-2.4-2.61.8-2.41.6-2.52.1-2.1
Delay disc. indifference point, 24s delay1.31.32.41.50.5-0.71.3-0.91.5-1.01.3
Delay disc. indifference point, 4s delay0.10.10.10.20.0-0.30.40.30.20.20.2
Delay disc. indifference point, 8s delay0.10.10.3-0.5-0.4-0.2-0.1-0.5-0.4-0.1-0.4
Delay discount exponential model param0.10.10.2-0.40.00.3-0.50.4-0.50.3-0.4
Delay discount hyperbolic model param0.00.00.1-0.00.30.0-0.00.1-0.0-0.1-0.0
Fecal boli incidents, locomotor time 12.02.23.61.20.6-1.61.9-1.81.4-1.71.1
Change in fecal boli incidents, locomotor task1.91.83.8-0.7-0.81.6-1.42.0-0.91.7-1.3
Time >=10cm from walls, locomotor time 11.71.73.7-1.9-1.90.3-0.90.4-1.80.8-1.2
Bouts of movement, locomotor time 11.41.62.21.31.4-1.11.5-0.91.4-1.31.2
Total resting periods, locomotor time 11.21.31.91.11.1-1.21.4-0.91.2-1.21.0
Rest time, locomotor task time 10.91.02.60.50.4-1.61.0-1.40.7-1.30.4
Distance moved, locomotor task time 11.92.14.0-0.7-1.32.0-1.12.0-1.02.0-0.5
Vertical activity count, locomotor time 12.52.65.1-1.1-1.32.1-1.42.2-1.42.1-0.7
Time >=10cm from walls, locomotor time 22.22.34.6-2.1-2.1-0.1-1.40.1-2.00.8-1.7
Bouts of movement, locomotor time 20.40.41.1-1.1-0.7-0.7-0.3-0.3-1.00.2-0.3
Total resting periods, locomotor time 20.30.31.0-1.0-0.2-0.8-0.2-0.3-0.90.0-0.3
Rest time, locomotor task time 20.40.52.00.61.4-0.70.8-0.10.6-0.30.1
Distance moved, locomotor task time 21.21.44.8-1.1-2.20.9-1.00.9-1.31.2-0.3
Vertical activity count, locomotor time 21.11.23.2-0.9-1.81.2-0.81.1-1.11.2-0.2
Weight adjusted by age0.10.20.7-0.00.20.30.40.8-0.10.50.2
Seeking ratio, delayed vs. immediate footshock1.11.32.90.21.6-1.30.5-1.70.6-1.60.0
Locomotion in novel chamber0.60.72.11.1-0.51.40.01.00.90.50.6
Locomotion in novel chamber post-restriction1.72.05.52.20.70.81.00.31.8-0.42.3
Progressive ratio0.40.42.20.71.5-0.30.40.10.7-0.20.4
Food seeking constrained by brief footshock0.00.00.10.30.00.20.1-0.10.20.10.1
Seeking ratio, punishment vs. effort0.70.92.6-1.1-1.60.6-1.0-0.1-1.10.4-0.9
Run reversals in cocaine runway, females2.22.25.1-2.0-0.60.6-1.70.7-1.81.2-2.3
Run reversals in cocaine runway, males0.40.40.8-0.80.2-0.1-0.9-0.5-0.7-0.3-0.7
Latency to leave start box in cocaine runway0.40.40.90.60.91.0-0.50.80.20.50.2
Latency to leave start box in cocaine runway, F0.70.81.21.10.9-0.60.7-0.80.9-0.91.0
Latency to leave start box in cocaine runway, M1.21.22.8-0.20.61.6-1.11.7-0.51.4-0.7
Cd content in liver1.92.13.41.51.4-1.11.7-1.01.5-1.41.8
Co content in liver1.51.83.5-0.8-0.21.5-1.51.9-1.01.8-1.1
Cu content in liver3.23.95.8-2.1-2.01.2-2.41.8-2.22.0-1.7
Fe content in liver1.21.43.41.80.70.40.90.41.7-0.41.8
K content in liver3.83.85.6-2.3-2.01.0-2.21.2-2.31.7-2.4
Mg content in liver0.90.91.8-1.3-0.90.1-1.10.2-1.20.5-1.3
Mn content in liver0.10.20.5-0.4-0.3-0.2-0.30.2-0.40.5-0.7
Na content in liver3.03.27.6-2.5-1.40.2-1.90.2-2.31.1-2.8
Rb content in liver0.91.13.2-0.10.11.6-1.01.8-0.31.4-0.2
Se content in liver0.20.30.7-0.1-0.80.8-0.50.7-0.20.6-0.1
Sr content in liver0.10.10.60.00.70.1-0.10.00.0-0.0-0.1
Zn content in liver2.42.65.8-2.4-1.4-0.1-1.60.1-2.30.9-2.0