Hub : Genes

Casp8

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000012331 0.09 0.06 4.9e-03 0.01 0.01 0.02 0.02 1.1e-02 7.8e-03 1.5e-03 1.7e-03
2 BLA gene expression ENSRNOG00000012331 0.05 0.04 5.6e-03 0.03 0.01 0 0.01 8.8e-03 7.9e-02 2.2e-01 1.1e-01
3 Brain gene expression ENSRNOG00000012331 0.04 0.02 1.5e-03 0.03 0.01 0.02 0.01 5.9e-04 1.3e-02 8.7e-03 1.4e-02
4 Brain mRNA stability ENSRNOG00000012331 0.04 0.02 7.6e-04 0.01 0.02 0.02 0.01 6.7e-02 3.6e-03 5.9e-03 3.4e-02
5 IL mRNA stability ENSRNOG00000012331 0.44 0.16 3.3e-03 -0 0.03 0.05 0.01 3.7e-01 8.5e-02 2.4e-02 2.1e-01
6 Liver gene expression ENSRNOG00000012331 0.12 0.06 7.9e-10 0.04 0.09 0.09 0.09 1.5e-05 5.0e-10 5.4e-10 1.0e-09
7 Liver mRNA stability ENSRNOG00000012331 0.03 0.02 1.7e-03 0 0.02 0.01 0.01 7.5e-02 4.2e-03 3.9e-02 3.7e-02
8 NAcc gene expression ENSRNOG00000012331 0.05 0.03 1.2e-03 0.01 0.03 0.02 0.01 5.6e-02 5.7e-03 7.5e-03 5.9e-02
9 PL gene expression ENSRNOG00000012331 0.04 0.03 2.3e-03 0.02 0.02 0.02 0.02 6.6e-03 6.0e-03 1.4e-02 7.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail0.92.914.33.80.50.51.2-1.41.7-1.31.90.3
BMI without tail1.02.05.72.01.21.2-0.8-1.20.70.32.41.7
Body weight0.10.30.8-0.90.20.3-0.60.0-0.70.20.50.6
Epididymis fat weight1.84.16.8-1.32.32.3-2.61.60.22.32.02.4
Glucose0.40.71.41.11.01.00.10.41.2-0.01.00.4
Heart weight1.31.83.2-0.5-1.5-1.51.3-0.5-1.8-1.8-1.1-1.3
Left kidney weight0.30.83.1-0.6-0.2-0.20.91.8-0.9-1.2-0.1-0.7
Right kidney weight0.20.61.6-1.0-0.4-0.40.60.7-1.3-0.9-0.3-0.6
Tail length1.64.823.3-4.80.30.3-2.41.7-2.22.0-0.90.9
Length with tail1.65.730.0-5.5-0.2-0.1-2.21.6-2.71.9-1.50.5
Length without tail0.81.76.7-2.6-0.9-0.80.21.2-1.3-0.1-1.8-1.0
Liver weight, left0.81.32.8-0.71.31.2-1.70.30.01.41.11.5
Liver weight, right2.13.47.5-2.7-2.0-1.90.7-0.1-2.7-1.1-2.1-1.5
Parametrial fat weight0.30.71.10.30.91.0-0.90.10.70.91.01.0
Retroperitoneal fat weight0.51.62.80.71.31.4-1.5-0.80.91.41.51.7
Intraocular pressure0.81.13.82.00.40.21.40.31.4-1.00.5-0.6
Extensor digitorum longus weight0.83.17.21.92.12.2-0.11.51.90.02.71.2
Soleus weight0.10.20.60.00.20.10.20.6-0.8-0.70.70.2
Tibialis anterior weight0.00.20.50.20.50.5-0.10.70.40.10.50.2
Tibia length1.33.716.9-4.1-0.6-0.6-0.72.4-2.50.4-1.7-0.6
Number of licking bursts0.70.81.2-0.8-1.0-1.00.80.4-0.9-0.8-1.1-1.0
Food consumed during 24 hour testing period0.30.41.81.40.20.10.7-0.20.9-0.50.4-0.2
Times rat made contact with spout0.80.92.81.70.80.7-0.3-0.81.30.51.10.8
Mean time between licks in bursts3.54.87.41.32.72.7-2.10.52.12.12.72.5
Mean num. licks in bursts1.92.33.81.91.61.6-0.9-0.41.81.01.91.5
Std. dev. time between licks in bursts0.40.51.91.40.70.70.20.30.9-0.10.80.3
Water consumed over 24 hours1.31.64.92.2-0.6-0.61.9-0.30.7-1.80.1-1.1
Indifference point 0 sec0.20.30.80.3-0.2-0.20.90.90.4-0.7-0.2-0.7
Indifference point AUC0.91.02.4-1.5-0.6-0.60.71.5-0.7-0.6-1.2-1.1
Indifference point function ln k0.40.62.20.90.30.3-0.6-1.50.30.50.70.8
Indifference point function log k0.40.62.20.90.30.3-0.6-1.50.30.50.70.8
Delay discounting total patch changes 0 sec0.40.61.80.5-0.5-0.51.40.70.3-1.1-0.4-1.1
Delay discounting total patch changes 12 sec0.50.73.3-0.6-0.1-0.10.91.80.3-0.6-0.7-1.0
Delay discounting total patch changes 18 sec0.81.13.30.4-0.1-0.11.61.81.0-1.1-0.3-1.2
Delay discounting total patch changes 24 sec0.80.91.5-1.0-0.9-0.81.01.1-0.5-0.8-1.2-1.2
Delay discounting total patch changes 6 sec0.71.12.60.0-1.1-0.91.50.5-0.6-1.6-0.7-1.3
Delay discounting time to switch 0 sec0.20.31.71.3-0.1-0.10.3-0.60.2-0.40.3-0.0
Delay discounting water rate 0 sec0.10.20.8-0.90.20.3-0.50.5-0.10.5-0.00.3
Delay discounting water rate 12 sec0.40.73.00.5-0.9-0.80.3-1.7-0.8-0.7-0.1-0.2
Delay discounting water rate 18 sec1.01.32.1-0.8-1.4-1.31.0-0.1-1.1-1.1-1.4-1.3
Delay discounting water rate 24 sec0.20.31.60.1-0.3-0.3-0.2-1.2-0.8-0.20.20.3
Delay discounting water rate 6 sec0.10.10.30.3-0.00.0-0.2-0.6-0.00.10.40.3
Locomotor activity0.30.51.30.60.70.8-0.01.10.70.00.90.4
Locomotor testing distance0.30.51.20.80.10.11.10.80.4-1.10.6-0.4
Locomotor testing rearing0.10.10.2-0.20.30.3-0.30.20.20.30.40.4
Light reinforcement 11.32.49.13.01.41.30.3-0.32.0-0.32.10.8
Light reinforcement 20.10.20.4-0.10.50.5-0.40.3-0.10.10.70.5
Reaction time number correct0.60.91.80.9-1.0-0.91.2-0.6-0.4-1.3-0.6-1.0
Reaction time mean minus median0.00.10.2-0.5-0.2-0.30.1-0.1-0.2-0.1-0.2-0.1
Reaction time mean minus median AUC0.50.71.0-0.5-1.0-1.00.9-0.3-0.4-0.8-1.0-1.0
Reaction time num false alarms1.52.14.11.71.91.8-0.70.61.50.72.01.4
Reaction time num false alarms AUC1.72.44.71.82.01.9-0.70.81.50.72.21.4
Reaction time trials correct on left0.60.91.80.9-1.0-0.91.2-0.6-0.4-1.3-0.6-1.0
Reaction time trials on left0.60.81.60.8-1.0-0.81.2-0.6-0.4-1.3-0.6-1.0
Reaction time mean1.11.54.1-1.60.80.8-1.80.30.32.00.31.2
Reaction time mean AUC1.01.33.5-1.40.90.8-1.70.40.51.90.41.2
Median of all reaction times1.82.46.7-1.91.11.1-2.30.60.62.60.41.6
Reaction time omissions0.40.51.3-0.10.50.6-1.1-0.40.41.10.60.9
Reaction time false alarm rate1.92.75.01.02.22.1-1.31.01.41.32.21.8
Reaction time premature initiation rate2.43.25.8-0.6-1.7-1.82.41.1-1.2-2.4-1.7-2.4
Reaction time premature initiations2.84.08.30.1-2.0-2.02.80.6-1.2-2.9-1.8-2.6
Std. dev. reaction times0.20.31.8-1.3-0.2-0.2-0.60.0-0.60.5-0.30.2
Reaction time trials completed0.60.81.60.8-1.0-0.81.2-0.6-0.4-1.3-0.6-1.0
Reaction time trials AUC0.40.61.20.8-0.9-0.71.0-0.5-0.4-1.1-0.5-0.9
Social response proportion0.40.51.7-1.3-0.3-0.2-0.20.7-1.3-0.2-0.5-0.2
Social responses0.81.04.0-1.80.40.4-0.62.0-0.90.4-0.20.1
Social time0.30.31.5-1.2-0.1-0.1-0.10.9-0.6-0.0-0.4-0.2
Conditioned locomotion0.91.12.4-0.61.11.1-1.50.7-0.11.30.91.3
Cocaine response after cond. corrected0.60.72.0-0.90.20.1-1.4-0.9-0.51.30.10.9
Cocaine response after cond. not corrected1.31.53.6-1.8-1.3-1.4-0.1-0.9-1.9-0.2-1.4-0.6
Cocaine response before conditioning5.46.69.5-1.5-2.8-2.82.80.6-2.5-3.1-2.8-3.1
Saline control response0.50.71.1-0.5-1.1-1.00.7-0.7-1.1-1.0-0.7-0.7
Condit. Reinf. active minus inactive responses2.22.76.1-2.5-1.8-1.80.50.2-2.2-0.7-2.1-1.4
Condit. Reinf. active-inactive response ratio3.13.36.5-1.8-2.2-2.21.3-0.2-1.7-1.2-2.6-2.0
Condit. Reinf. active responses1.62.36.4-2.5-1.5-1.40.40.6-1.9-0.5-2.0-1.2
Condit. Reinf. inactive responses0.20.20.9-1.00.20.2-0.30.9-0.30.2-0.10.0
Condit. Reinf. lever presses1.72.34.5-0.7-1.6-1.62.00.7-0.5-1.6-1.9-2.1
Condit. Reinf. lever reinforcers received1.82.66.6-2.6-1.7-1.60.60.6-2.0-0.7-2.1-1.4
Pavlov. Cond. lever latency1.62.24.30.71.51.6-1.8-0.50.41.42.02.1
Pavlov. Cond. magazine entry latency0.30.30.7-0.3-0.3-0.40.70.40.6-0.2-0.9-0.8
Pavlov. Cond. change in total contacts1.31.85.2-2.3-0.9-1.00.61.5-0.5-0.1-2.0-1.4
Pavlov. Cond. index score1.01.33.2-1.2-0.9-1.01.11.00.0-0.5-1.8-1.6
Pavlov. Cond. latency score1.01.33.1-1.1-0.9-1.01.21.10.0-0.6-1.8-1.6
Pavlov. Cond. lever contacts1.82.54.8-1.2-1.5-1.61.80.9-0.5-1.4-2.2-2.2
Pavlov. Cond. magazine entry number0.30.41.10.80.40.4-0.5-0.8-0.20.11.10.9
Pavlov. Cond. intertrial magazine entries0.40.51.30.5-0.6-0.60.4-0.8-1.1-1.00.1-0.2
Pavlov. Cond. lever-magazine prob. diff.0.91.22.9-1.3-0.8-0.91.01.20.1-0.4-1.7-1.4
Pavlov. Cond. response bias1.01.43.2-1.1-1.2-1.21.30.8-0.3-0.9-1.8-1.7
Conditioned reinforcement - actives0.20.20.40.10.60.5-0.30.60.60.40.40.3
Conditioned reinforcement - inactives1.01.14.7-1.20.80.8-0.82.20.61.10.00.4
Conditioned locomotion0.20.31.01.00.40.40.00.20.70.00.70.3
Intermittent access intake day 1-15 change2.52.55.00.3-1.7-1.82.0-1.3-1.1-2.2-1.2-1.7
Intermittent access intake escalation3.13.15.7-0.1-2.0-2.02.2-1.1-1.3-2.4-1.5-2.0
Intermittent access intake escalation 22.72.63.7-0.7-1.8-1.91.7-1.5-1.6-1.9-1.5-1.7
Intermitt. access day 1 inactive lever presses0.50.61.80.90.70.70.21.11.30.20.50.1
Intermitt. access day 15 inactive lever presses0.40.40.7-0.6-0.4-0.50.70.7-0.5-0.7-0.7-0.8
Intermitt. access escalation Index3.02.74.40.72.12.0-1.51.51.41.61.81.7
Intermittent access day 1 total infusions0.50.51.70.60.70.6-0.6-0.01.31.10.30.6
Intermittent access day 15 total infusions0.60.61.60.5-0.7-0.81.3-0.10.4-0.9-0.8-1.1
Intermittent access terminal intake (last 3 days)0.91.02.40.3-0.9-1.11.6-0.10.3-1.2-1.1-1.4
Intermittent access total infusions0.20.20.80.3-0.1-0.20.60.30.9-0.1-0.4-0.5
Intermittent access day 1 locomotion0.50.52.30.60.40.40.21.01.50.5-0.0-0.1
Intermittent access day 15 total locomotion0.40.40.9-0.2-0.4-0.50.90.70.2-0.6-0.7-0.9
Intermittent access total locomotion0.20.21.30.60.40.30.10.31.20.40.10.0
Intermittent access standard deviation0.91.01.70.2-1.1-1.11.3-0.80.4-0.9-1.1-1.2
Cocaine induced anxiety0.20.20.60.20.60.6-0.10.80.0-0.10.80.4
Post-drug Anxiety0.20.20.90.60.10.1-0.3-1.0-0.3-0.00.60.5
Baseline Anxiety0.40.41.9-0.4-0.5-0.5-0.5-1.4-0.30.6-0.60.1
Lifetime Intake0.20.21.10.60.20.10.30.11.10.1-0.0-0.2
Incentive Sensitization - Responses0.60.61.1-0.41.00.8-0.90.90.71.10.50.7
Incentive Sensitization - Breakpoint0.80.81.4-0.41.20.9-1.00.90.71.10.60.8
Progressive ratio test 1 active lever presses0.40.41.90.50.20.10.71.40.9-0.3-0.2-0.6
Progressive ratio test 1 breakpoint0.60.61.30.4-0.3-0.41.11.10.6-0.8-0.6-1.0
Progressive ratio test 1 inactive lever presses2.22.46.82.61.41.40.21.32.50.31.50.6
Progressive ratio test 2 active lever presses0.20.21.20.10.30.10.41.10.8-0.1-0.1-0.3
Progressive ratio test 2 breakpoint0.30.31.00.40.2-0.10.81.00.9-0.4-0.2-0.6
Progressive ratio test 2 inactive lever presses0.60.72.30.50.90.8-0.11.31.50.60.40.2
Total sessions with >9 infusions0.40.41.51.20.20.20.60.41.2-0.30.3-0.2
Short access day 1 total inactive lever presses0.10.10.2-0.00.40.3-0.20.40.20.20.30.2
Short access day 10 total inactive lever presses0.40.40.70.20.70.7-0.80.00.60.80.60.8
Short access day 1 total infusions0.20.30.60.7-0.3-0.30.8-0.30.6-0.5-0.2-0.5
Short access day 10 total infusions0.10.10.20.4-0.2-0.20.4-0.20.4-0.2-0.2-0.3
Short access total infusions0.30.31.51.10.20.20.2-0.31.20.10.30.1
Short access day 1 locomotion0.80.85.0-0.10.30.30.72.21.1-0.2-0.2-0.6
Short access day 10 total locomotion0.30.30.80.1-0.5-0.60.70.20.4-0.3-0.9-0.8
Short access total locomotion0.20.21.10.70.20.30.20.41.10.20.20.0
Compulsive drug intake0.40.40.9-0.4-0.6-0.50.70.90.1-0.4-0.9-0.9
One hour access (0.3 mA shock)0.80.92.0-0.3-1.0-0.91.30.60.6-0.6-1.4-1.4
One hour access (shock baseline)0.00.00.2-0.00.0-0.10.20.00.50.1-0.2-0.2
Number of responses in last shaping day0.70.72.7-0.3-0.2-0.41.21.70.0-1.0-0.6-1.0
Context. condit. distance diff. score0.60.84.80.7-0.0-0.1-0.5-2.20.90.80.10.5
Locomotion velocity, session 11.61.73.21.41.01.1-1.0-1.41.81.31.31.3
Locomotion distance, session 10.50.73.81.3-0.2-0.20.1-1.90.3-0.20.40.3
Locomotion velocity, session 20.60.71.30.80.70.7-0.8-1.10.60.71.11.1
Locomotion distance, session 21.21.74.60.91.51.5-1.1-0.50.50.72.11.7
Locomotion velocity, session 31.11.34.01.00.60.6-1.0-2.00.71.01.21.3
Locomotion distance, session 30.30.30.6-0.60.20.2-0.8-0.7-0.10.70.20.6
Stereotopy head waving bouts, day 30.30.41.31.1-0.2-0.10.90.50.7-0.7-0.1-0.6
Stereotopy head waving duration, day 30.70.84.02.0-0.3-0.21.1-0.50.6-1.10.4-0.5
Locomotion velocity, session 70.60.61.71.30.50.50.0-0.91.30.20.80.4
Locomotion distance, session 70.91.11.60.31.31.3-1.1-0.11.01.21.21.3
Stereotopy head waving bouts, day 70.80.91.7-0.8-1.2-1.20.1-1.2-1.3-0.3-0.9-0.4
Stereotopy head waving duration, day 70.50.63.00.3-0.9-0.90.2-1.7-0.9-0.5-0.2-0.1
Locomotion velocity, session 80.60.85.00.6-0.1-0.0-0.6-2.20.30.60.40.7
Locomotion distance, session 80.60.93.80.50.40.4-0.9-2.00.60.90.71.1
Degree of sensitization distance0.20.20.80.90.20.20.30.00.6-0.20.3-0.0
Degree of sensitization stereotypy0.70.83.1-0.8-0.5-0.5-1.0-1.7-1.30.5-0.10.6
Condit. Reinf. active minus inactive responses2.22.54.1-1.7-1.5-1.51.51.2-1.2-1.4-2.0-1.9
Condit. Reinf. active-inactive response ratio0.91.01.6-0.9-1.0-1.01.10.8-0.7-1.0-1.1-1.3
Condit. Reinf. active responses1.72.15.6-2.4-1.2-1.20.81.2-1.5-0.8-1.8-1.4
Condit. Reinf. inactive responses0.30.31.6-1.30.20.2-0.50.8-0.30.5-0.10.2
Incentive salience index mean3.34.06.5-2.4-1.9-1.91.71.5-1.8-1.6-2.5-2.3
Condit. Reinf. lever presses1.41.93.8-2.0-1.2-1.20.91.1-1.3-0.8-1.8-1.5
Time in familiar zone, hab. session 12.22.07.30.6-1.7-1.80.9-2.7-1.1-1.2-0.7-0.8
Time in novel zone, hab. session 11.51.53.4-0.51.51.5-1.01.81.11.40.60.8
Total zone transitions, hab. session 10.30.41.0-0.9-0.6-0.6-0.4-1.0-0.80.2-0.50.0
Total locomotion distance, hab. session 11.62.24.1-2.0-1.7-1.60.90.1-1.6-1.0-2.0-1.5
Locomotion velocity, hab. session 11.21.74.1-2.0-1.2-1.20.80.7-1.4-0.8-1.6-1.3
Time in familiar zone, hab. session 21.21.22.3-0.3-1.2-1.31.50.1-0.4-1.3-1.2-1.5
Time in novel zone, hab. session 21.21.31.90.91.31.4-1.1-0.10.91.01.41.3
Total zone transitions, hab. session 20.30.41.00.70.40.3-0.4-1.00.40.30.80.7
Total locomotion distance, hab. session 20.10.20.40.60.10.1-0.1-0.7-0.1-0.20.60.4
Locomotion velocity, hab. session 20.10.10.50.60.30.2-0.1-0.40.0-0.10.70.4
Novel to familiar place preference ratio0.20.20.50.50.30.4-0.4-0.40.10.30.70.6
Novelty place preference0.10.10.30.40.20.3-0.2-0.30.10.10.50.4
Time in novel zone, NPP test0.10.10.20.50.00.1-0.1-0.5-0.1-0.10.40.3
Total zone transitions, NPP test0.10.10.4-0.0-0.4-0.40.0-0.6-0.3-0.1-0.4-0.2
Total locomotion distance, NPP test1.21.62.8-0.4-1.4-1.41.5-0.2-1.1-1.7-1.2-1.5
Locomotion velocity, NPP test0.91.22.4-0.3-1.2-1.21.50.1-0.7-1.5-1.1-1.4
Pavlov. Cond. lever latency1.21.63.01.41.41.5-0.70.21.50.81.71.2
Pavlov. Cond. magazine entry latency2.93.76.1-1.6-2.1-2.11.80.8-1.9-1.8-2.5-2.3
Pavlov. Cond. change in total contacts2.82.94.5-1.3-1.9-1.91.60.2-1.8-1.7-2.1-2.0
Pavlov. Cond. index score2.73.56.9-1.7-2.1-2.11.50.3-1.9-1.5-2.6-2.2
Pavlov. Cond. latency score2.93.77.2-1.7-2.2-2.31.4-0.1-2.0-1.5-2.7-2.2
Pavlov. Cond. lever contacts1.72.14.0-1.1-1.6-1.71.3-0.2-1.3-1.2-2.0-1.7
Pavlov. Cond. magazine entry number1.92.44.01.41.61.7-1.3-0.61.71.42.01.8
Pavlov. Cond. intertrial magazine entries0.30.30.7-0.50.30.4-0.8-0.5-0.00.80.40.8
Pavlov. Cond. lever-magazine prob. diff.2.83.56.9-1.5-2.1-2.11.70.3-1.7-1.6-2.6-2.3
Pavlov. Cond. response bias2.42.95.4-1.9-1.7-1.71.41.0-1.7-1.3-2.3-2.0
Bone: apparent density1.83.07.9-1.3-2.0-2.01.0-0.6-2.8-1.7-1.6-1.4
Bone surface1.32.37.7-2.6-1.1-1.1-0.01.0-2.8-0.6-1.3-0.7
Bone volume1.42.47.9-2.2-1.5-1.50.40.4-2.8-1.1-1.4-1.0
Bone: connectivity density1.21.96.3-0.7-1.5-1.51.0-0.3-2.5-1.8-0.8-1.0
Bone: cortical apparent density1.41.97.81.71.31.20.71.42.80.20.8-0.0
Bone: cortical area1.11.610.2-1.70.60.7-0.23.2-0.10.5-0.4-0.3
Bone: cortical porosity1.31.56.0-2.4-0.8-0.8-0.31.1-1.60.2-1.4-0.6
Bone: cortical porosity2.02.28.1-2.8-1.0-1.0-0.11.3-2.1-0.1-1.7-0.8
Bone: cortical thickness0.91.58.40.11.21.20.22.91.30.30.4-0.1
Bone: cortical thickness0.80.92.30.5-0.7-0.71.50.80.2-1.2-0.9-1.4
Bone: cortical tissue density1.51.97.81.81.31.30.61.22.80.20.90.1
Bone: elastic displacement1.51.72.50.8-1.6-1.61.5-1.6-0.6-1.5-1.1-1.3
Bone: elastic work0.40.50.7-0.3-0.8-0.80.80.1-0.8-0.8-0.8-0.8
Bone: endosteal estimation1.43.010.9-3.3-1.3-1.20.31.4-2.5-0.6-1.9-1.2
Bone: endosteal perimeter1.02.18.3-2.9-1.0-1.0-0.30.9-2.3-0.1-1.4-0.6
Bone: final force1.01.78.8-2.10.10.10.13.0-1.1-0.2-0.6-0.5
Bone: final moment1.01.67.6-1.7-0.3-0.20.72.8-1.1-0.7-0.8-1.0
Bone: marrow area1.53.211.4-3.4-1.3-1.30.41.5-2.4-0.6-1.9-1.3
Bone: maximum diameter1.01.87.4-2.70.10.1-0.62.3-0.80.8-1.1-0.3
Bone: maximum force1.01.85.6-1.8-0.6-0.60.62.4-1.8-1.0-0.9-1.0
Bone: maximum moment1.11.94.3-1.3-0.9-0.91.22.1-1.7-1.5-1.0-1.4
Bone: minimum diameter1.32.411.8-2.5-0.10.00.43.4-1.1-0.4-1.0-0.9
Bone: periosteal estimation1.42.910.6-3.3-0.5-0.50.12.9-1.7-0.2-1.5-1.0
Bone: periosteal perimeter0.91.55.4-2.3-0.6-0.60.11.7-1.4-0.2-1.3-0.8
Bone: post-yield work0.71.02.70.2-0.8-0.81.40.7-0.7-1.7-0.5-1.1
Bone: stiffness0.91.55.8-2.4-0.2-0.2-0.61.8-1.80.2-0.7-0.1
Bone: tissue strength0.20.20.6-0.30.10.10.10.8-0.8-0.50.40.1
Bone: trabecular number1.32.17.5-1.1-1.7-1.70.5-1.0-2.7-1.3-1.0-0.8
Bone: trabecular spacing1.51.94.40.61.61.6-1.30.02.11.81.11.3
Bone: trabecular thickness1.51.83.6-0.5-1.5-1.61.2-0.1-1.9-1.7-1.1-1.3
Bone: trabecular tissue density0.50.73.1-0.70.50.50.11.81.10.6-0.5-0.3
Breakpoint value in progressive ratio session1.41.62.4-0.8-1.4-1.41.30.2-1.2-1.3-1.5-1.6
Distance traveled before self-admin1.41.56.0-2.5-1.0-1.00.00.2-1.8-0.3-1.2-0.7
Distance traveled after self-admin0.30.31.4-0.80.30.3-0.31.2-0.50.10.20.2
Delta time in closed arm before/after self-admin0.30.30.7-0.8-0.6-0.60.40.4-0.5-0.3-0.8-0.6
Delta time in open arm before/after self-admin1.31.36.7-2.6-0.6-0.4-0.50.5-1.20.6-1.3-0.4
Diff in mean of infusions in LGA sessions2.42.74.4-0.9-2.0-2.01.3-1.1-2.1-1.7-1.7-1.6
Extinction: sum of active levers before priming0.90.91.7-0.4-1.0-1.00.9-0.3-1.3-1.1-0.9-1.0
Active lever presses in extinction session 60.30.31.0-0.00.30.3-0.9-0.40.41.00.20.7
Delta distance traveled before/after self-admin0.60.71.91.40.90.80.00.70.9-0.01.10.5
Delta ambulatory time before/after self-admin1.31.42.11.31.41.4-0.41.21.50.61.40.9
Time in closed arm before self-admin0.50.52.2-1.5-0.5-0.4-0.4-0.4-1.00.3-0.8-0.1
Time in closed arm after self-admin0.80.81.9-1.4-0.9-0.9-0.2-1.1-1.20.0-1.0-0.3
Time in open arm before self-admin2.22.46.22.51.61.50.01.22.00.22.00.9
Time in open arm after self-admin0.40.51.3-1.00.50.6-0.61.10.30.9-0.20.2
Sum of active levers in priming session hrs 5-60.30.31.0-1.00.10.0-0.60.5-0.70.4-0.10.2
Time to tail flick, vehicle, before self-admin0.20.20.70.20.60.6-0.10.90.50.20.40.2
Time to tail flick, vehicle, after self-admin0.20.30.50.20.70.6-0.40.60.40.30.70.5
Time to tail flick, test, before self-admin0.90.91.30.31.11.0-1.10.70.71.11.01.1
Time to tail flick, test, after self-admin1.01.03.31.8-0.6-0.70.9-1.80.4-0.90.1-0.4
Delta time to tail flick, vehicle, before/after SA0.20.20.80.80.10.00.0-0.90.1-0.20.50.2
Delta time to tail flick, test, before/after SA2.32.13.81.3-1.5-1.51.9-1.4-0.2-1.9-0.9-1.5
Ambulatory time before self-admin0.60.62.3-1.5-0.5-0.6-0.4-0.2-1.5-0.1-0.30.1
Ambulatory time after self-admin0.40.42.7-0.40.50.5-0.11.6-0.3-0.20.60.2
Total heroin consumption0.60.71.2-0.4-0.6-0.51.01.0-0.7-1.1-0.7-1.0
Area under the delay curve0.10.10.20.30.40.3-0.4-0.00.10.40.30.4
Delay disc. indifference point, 0s delay0.60.73.31.8-0.10.00.7-1.00.6-0.80.7-0.1
Delay disc. indifference point, 16s delay0.60.61.1-0.5-0.9-1.10.3-0.8-1.1-0.5-0.9-0.6
Delay disc. indifference point, 2s delay0.50.62.91.70.10.20.2-1.10.5-0.30.70.3
Delay disc. indifference point, 24s delay0.30.30.7-0.1-0.2-0.30.60.8-0.7-0.7-0.5-0.6
Delay disc. indifference point, 4s delay0.50.51.41.20.50.6-0.3-0.81.00.40.70.5
Delay disc. indifference point, 8s delay0.50.61.3-0.80.70.6-1.20.7-0.50.90.30.8
Delay discount exponential model param0.00.00.1-0.2-0.3-0.20.30.00.1-0.3-0.1-0.3
Delay discount hyperbolic model param0.10.10.2-0.4-0.4-0.40.30.1-0.2-0.3-0.3-0.4
Fecal boli incidents, locomotor time 10.50.61.3-0.9-0.7-0.70.50.3-0.9-0.5-1.1-0.9
Change in fecal boli incidents, locomotor task0.10.10.20.40.10.20.20.10.4-0.10.30.1
Time >=10cm from walls, locomotor time 10.50.52.4-0.90.60.6-0.41.60.20.50.10.2
Bouts of movement, locomotor time 10.80.92.8-0.3-0.9-0.91.10.50.2-0.5-1.7-1.5
Total resting periods, locomotor time 10.60.61.50.4-0.4-0.51.00.51.0-0.2-1.2-1.1
Rest time, locomotor task time 11.82.07.51.51.51.5-0.31.02.71.20.90.7
Distance moved, locomotor task time 11.01.14.4-2.1-0.0-0.0-1.20.5-1.80.50.10.6
Vertical activity count, locomotor time 10.30.40.9-0.90.00.0-0.9-0.2-0.80.60.30.7
Time >=10cm from walls, locomotor time 21.01.02.80.71.21.2-0.90.20.30.61.71.3
Bouts of movement, locomotor time 20.40.40.90.9-0.6-0.70.5-0.9-0.4-0.7-0.2-0.4
Total resting periods, locomotor time 20.40.50.70.8-0.7-0.80.7-0.6-0.3-0.7-0.5-0.6
Rest time, locomotor task time 20.91.04.10.50.90.9-0.21.52.01.00.30.2
Distance moved, locomotor task time 20.30.41.4-1.10.20.2-0.40.5-1.2-0.20.40.3
Vertical activity count, locomotor time 20.50.61.91.40.50.50.3-0.40.3-0.71.40.5
Weight adjusted by age1.01.12.3-0.6-1.1-1.10.8-0.7-1.5-1.2-1.0-1.0
Seeking ratio, delayed vs. immediate footshock0.50.61.90.1-0.9-0.8-0.2-1.4-1.3-0.3-0.10.1
Locomotion in novel chamber4.75.912.01.9-2.4-2.53.4-1.7-0.7-3.5-1.6-2.7
Locomotion in novel chamber post-restriction0.80.91.5-0.7-0.9-0.91.10.6-0.8-1.1-1.1-1.2
Progressive ratio0.91.02.51.60.91.0-0.7-0.31.20.71.21.0
Food seeking constrained by brief footshock0.80.93.1-1.2-0.9-0.90.4-0.5-1.8-0.9-0.7-0.6
Seeking ratio, punishment vs. effort1.82.25.8-2.4-1.3-1.30.6-0.1-2.4-1.1-1.4-1.1
Run reversals in cocaine runway, females0.30.30.70.30.70.8-0.5-0.10.70.70.50.6
Run reversals in cocaine runway, males0.30.30.7-0.5-0.5-0.50.50.40.1-0.1-0.8-0.7
Latency to leave start box in cocaine runway1.11.25.82.40.50.40.6-0.31.7-0.41.00.2
Latency to leave start box in cocaine runway, F0.50.61.91.30.60.60.10.11.40.20.70.3
Latency to leave start box in cocaine runway, M2.12.04.71.4-1.5-1.52.0-0.7-0.3-2.2-0.6-1.5
Cd content in liver0.10.10.2-0.3-0.2-0.2-0.2-0.2-0.40.0-0.20.0
Co content in liver0.91.02.80.4-1.2-1.30.7-1.7-0.1-0.5-1.3-0.9
Cu content in liver0.40.42.3-1.10.40.4-0.11.5-0.10.2-0.2-0.2
Fe content in liver2.22.63.7-0.6-1.9-1.91.70.0-1.8-1.9-1.7-1.9
K content in liver0.40.41.4-1.20.20.3-0.61.0-0.00.8-0.30.2
Mg content in liver0.10.10.2-0.5-0.4-0.20.20.3-0.5-0.3-0.3-0.3
Mn content in liver0.50.61.91.1-0.3-0.21.0-0.41.4-0.4-0.3-0.6
Na content in liver0.80.82.8-1.7-0.4-0.40.21.3-0.7-0.1-1.1-0.8
Rb content in liver0.70.82.3-0.60.40.4-1.5-1.0-0.41.20.61.2
Se content in liver0.40.51.2-0.2-0.6-0.41.00.8-0.6-1.1-0.5-0.9
Sr content in liver1.81.73.20.41.81.6-0.91.41.71.31.21.0
Zn content in liver0.80.91.90.31.41.3-0.61.00.90.61.10.8