Hub : Genes

Urgcp

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	alternative TSS	ENSRNOT00000016468	0.2	0.29	3.9e-03	0.04	0.04	0.04	0.04	3.7e-03	4.1e-03	3.1e-03	2.2e-03
2	BLA	isoform ratio	ENSRNOT00000016468	0.29	0.32	4.5e-03	0.04	0.03	0.05	0.05	3.3e-03	6.1e-03	1.3e-03	1.7e-03
3	Brain	isoform ratio	ENSRNOT00000016468	0.03	0.03	6.8e-04	0.02	0.03	0.02	0.02	9.6e-03	5.1e-04	6.1e-03	7.4e-03
4	PL	alternative TSS	ENSRNOT00000076874	0.13	0.08	4.6e-03	0.03	0.01	0.01	0.02	2.6e-03	2.7e-02	7.2e-02	7.5e-03
5	PL	alternative TSS	ENSRNOT00000094862	0.13	0.08	4.3e-03	0.03	0.02	0.03	0.02	2.2e-03	1.8e-02	3.7e-03	6.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
BMI with tail	0.0	0.0	0.1	0.2	0.3	0.1	0.2	-0.2
BMI without tail	0.0	0.0	0.1	0.2	0.2	-0.1	0.1	-0.1
Body weight	1.0	4.3	8.2	2.9	2.7	2.2	0.8	-0.8
Epididymis fat weight	0.1	0.3	0.8	-0.7	-0.6	-0.9	0.3	-0.3
Glucose	11.9	18.2	30.0	3.1	3.4	5.5	-4.5	4.5
Heart weight	0.8	1.1	2.0	-1.0	-0.7	-0.3	-1.4	1.4
Left kidney weight	0.4	1.2	2.8	0.1	-0.3	-0.6	1.7	-1.7
Right kidney weight	1.0	2.7	3.7	-1.0	-1.3	-1.9	1.9	-1.9
Tail length	1.0	3.2	6.6	2.6	2.4	1.8	0.5	-0.5
Length with tail	1.4	5.1	10.2	3.2	2.8	2.4	1.0	-1.0
Length without tail	0.6	1.4	2.6	1.6	1.3	1.5	0.5	-0.5
Liver weight, left	1.9	3.1	4.8	-1.4	-1.7	-2.2	1.7	-1.7
Liver weight, right	5.1	8.5	11.7	-1.9	-2.5	-3.1	3.4	-3.4
Parametrial fat weight	0.7	1.3	3.5	1.3	1.1	1.9	-0.1	0.1
Retroperitoneal fat weight	0.1	0.4	1.1	0.0	-0.0	-0.1	1.0	-1.0
Intraocular pressure	0.2	0.3	0.6	0.5	0.3	0.8	-0.4	0.4
Extensor digitorum longus weight	2.1	8.5	15.1	3.9	3.8	3.6	-0.4	0.4
Soleus weight	0.8	2.3	4.2	2.0	1.4	1.0	1.5	-1.5
Tibialis anterior weight	0.8	2.8	4.7	2.2	1.9	2.1	-0.8	0.8
Tibia length	0.4	1.0	2.3	0.2	-0.2	-0.7	1.5	-1.5
Number of licking bursts	2.3	2.7	5.6	2.4	2.1	1.9	-0.3	0.3
Food consumed during 24 hour testing period	1.7	2.0	3.1	1.3	1.4	1.8	-1.2	1.2
Times rat made contact with spout	3.1	3.5	8.3	-0.7	-0.4	0.5	-2.9	2.9
Mean time between licks in bursts	0.6	0.8	1.5	0.3	0.3	0.9	-1.2	1.2
Mean num. licks in bursts	2.7	3.3	5.9	-2.4	-2.0	-1.3	-1.6	1.6
Std. dev. time between licks in bursts	0.1	0.1	0.3	-0.2	0.0	0.2	-0.5	0.5
Water consumed over 24 hours	1.5	1.8	2.4	0.9	1.0	1.5	-1.5	1.5
Indifference point 0 sec	2.4	3.9	4.4	1.9	1.8	2.0	-2.1	2.1
Indifference point AUC	0.4	0.4	0.9	0.1	0.1	0.5	-1.0	1.0
Indifference point function ln k	0.4	0.6	1.3	0.2	0.4	-0.1	1.1	-1.1
Indifference point function log k	0.4	0.6	1.3	0.2	0.4	-0.1	1.1	-1.1
Delay discounting total patch changes 0 sec	2.7	4.4	5.4	1.8	1.9	2.1	-2.3	2.3
Delay discounting total patch changes 12 sec	1.9	2.5	4.0	1.1	1.1	1.5	-2.0	2.0
Delay discounting total patch changes 18 sec	2.9	3.8	6.4	1.1	1.1	1.9	-2.5	2.5
Delay discounting total patch changes 24 sec	2.4	3.0	5.7	-1.4	-1.1	-0.5	-2.4	2.4
Delay discounting total patch changes 6 sec	2.6	3.9	4.5	1.7	1.9	2.1	-2.1	2.1
Delay discounting time to switch 0 sec	0.5	0.7	1.0	-0.7	-0.9	-1.0	0.7	-0.7
Delay discounting water rate 0 sec	1.9	3.0	4.1	1.6	1.9	2.0	-1.5	1.5
Delay discounting water rate 12 sec	0.1	0.2	0.5	0.4	0.7	0.5	-0.2	0.2
Delay discounting water rate 18 sec	1.6	2.1	5.2	0.3	0.2	-0.5	2.3	-2.3
Delay discounting water rate 24 sec	0.0	0.0	0.1	-0.3	-0.1	0.2	0.2	-0.2
Delay discounting water rate 6 sec	0.4	0.6	0.9	0.6	0.7	0.5	0.9	-0.9
Locomotor activity	0.9	1.4	2.9	0.3	0.0	1.0	-1.7	1.7
Locomotor testing distance	0.1	0.2	0.6	0.8	0.5	0.4	0.0	-0.0
Locomotor testing rearing	1.4	2.2	3.3	1.6	1.5	1.8	-1.3	1.3
Light reinforcement 1	0.1	0.1	0.2	0.2	0.5	0.4	0.4	-0.4
Light reinforcement 2	1.6	2.1	5.0	0.5	0.3	-0.2	2.2	-2.2
Reaction time number correct	0.3	0.5	1.0	-0.3	-0.2	0.4	-1.0	1.0
Reaction time mean minus median	1.9	2.5	3.5	-1.9	-1.9	-1.3	-1.4	1.4
Reaction time mean minus median AUC	1.6	2.0	2.6	-1.6	-1.6	-1.2	-1.3	1.3
Reaction time num false alarms	0.8	1.0	2.5	1.2	1.6	0.7	0.6	-0.6
Reaction time num false alarms AUC	1.0	1.4	2.6	1.3	1.6	0.6	1.0	-1.0
Reaction time trials correct on left	0.3	0.5	1.0	-0.3	-0.2	0.4	-1.0	1.0
Reaction time trials on left	0.3	0.5	1.1	-0.3	-0.2	0.4	-1.0	1.0
Reaction time mean	0.5	0.7	1.3	-1.0	-1.1	-1.1	-0.0	0.0
Reaction time mean AUC	0.8	1.1	2.0	-1.3	-1.4	-1.4	0.2	-0.2
Median of all reaction times	0.3	0.4	0.7	-0.6	-0.8	-0.8	0.5	-0.5
Reaction time omissions	0.6	0.8	1.4	-1.2	-1.2	-1.2	-0.2	0.2
Reaction time false alarm rate	1.3	1.9	2.6	1.4	1.6	0.3	1.5	-1.5
Reaction time premature initiation rate	1.9	2.5	4.1	-1.7	-1.5	-2.0	1.3	-1.3
Reaction time premature initiations	0.8	1.1	2.0	-1.4	-1.2	-1.3	0.5	-0.5
Std. dev. reaction times	1.1	1.6	2.5	-1.5	-1.6	-1.3	-0.9	0.9
Reaction time trials completed	0.3	0.5	1.1	-0.3	-0.2	0.4	-1.0	1.0
Reaction time trials AUC	0.3	0.4	0.9	-0.2	-0.1	0.5	-0.9	0.9
Social response proportion	1.0	1.1	1.8	1.2	1.2	1.4	0.5	-0.5
Social responses	1.4	1.7	3.7	1.4	1.5	1.9	-0.6	0.6
Social time	0.2	0.3	0.5	0.5	0.6	0.7	-0.2	0.2
Conditioned locomotion	1.4	1.7	3.5	-0.3	-0.4	-1.2	1.9	-1.9
Cocaine response after cond. corrected	0.8	0.9	2.0	1.4	1.1	1.2	-0.2	0.2
Cocaine response after cond. not corrected	0.9	1.0	2.4	1.5	1.1	1.2	0.2	-0.2
Cocaine response before conditioning	0.4	0.5	0.5	-0.7	-0.7	-0.7	0.7	-0.7
Saline control response	0.3	0.5	0.7	-0.9	-0.5	-0.5	-0.7	0.7
Condit. Reinf. active minus inactive responses	0.3	0.3	0.6	-0.8	-0.7	-0.7	0.1	-0.1
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.2	0.2	0.1	-0.0	0.4	-0.4
Condit. Reinf. active responses	0.5	0.6	1.3	-1.1	-1.0	-0.9	0.2	-0.2
Condit. Reinf. inactive responses	0.8	1.0	2.2	-1.5	-1.3	-1.0	-0.4	0.4
Condit. Reinf. lever presses	0.2	0.3	0.6	-0.8	-0.6	-0.7	0.0	-0.0
Condit. Reinf. lever reinforcers received	0.3	0.5	1.0	-1.0	-0.8	-0.8	0.2	-0.2
Pavlov. Cond. lever latency	3.0	4.1	7.5	2.7	2.4	1.9	1.3	-1.3
Pavlov. Cond. magazine entry latency	0.0	0.0	0.0	-0.2	-0.1	-0.0	-0.2	0.2
Pavlov. Cond. change in total contacts	0.3	0.4	0.7	-0.8	-0.8	-0.6	-0.3	0.3
Pavlov. Cond. index score	1.0	1.3	2.5	-1.6	-1.5	-1.2	-0.5	0.5
Pavlov. Cond. latency score	0.9	1.1	2.1	-1.5	-1.3	-1.2	-0.3	0.3
Pavlov. Cond. lever contacts	2.7	3.7	6.8	-2.6	-2.4	-1.8	-1.1	1.1
Pavlov. Cond. magazine entry number	0.6	0.7	1.7	0.5	0.3	-0.1	1.3	-1.3
Pavlov. Cond. intertrial magazine entries	0.0	0.0	0.1	0.3	0.3	0.1	0.1	-0.1
Pavlov. Cond. lever-magazine prob. diff.	0.9	1.2	2.2	-1.5	-1.4	-1.1	-0.5	0.5
Pavlov. Cond. response bias	1.6	2.2	3.6	-1.9	-1.8	-1.1	-1.3	1.3
Conditioned reinforcement - actives	0.1	0.1	0.3	-0.4	-0.6	-0.0	0.2	-0.2
Conditioned reinforcement - inactives	0.0	0.0	0.0	0.2	-0.0	0.2	0.1	-0.1
Conditioned locomotion	0.1	0.2	0.3	-0.4	-0.4	0.1	0.5	-0.5
Intermittent access intake day 1-15 change	1.7	1.7	3.9	-0.2	-0.1	0.9	-2.0	2.0
Intermittent access intake escalation	1.5	1.5	3.4	-0.3	-0.2	0.7	-1.9	1.9
Intermittent access intake escalation 2	2.1	2.0	4.9	-0.3	-0.1	0.6	-2.2	2.2
Intermitt. access day 1 inactive lever presses	1.5	1.7	3.3	-0.7	-0.6	-0.9	1.8	-1.8
Intermitt. access day 15 inactive lever presses	1.0	1.1	1.6	1.1	1.2	1.3	-0.8	0.8
Intermitt. access escalation Index	1.5	1.3	3.0	0.4	0.4	0.7	-1.7	1.7
Intermittent access day 1 total infusions	0.6	0.7	1.1	-0.3	-0.8	-0.7	1.1	-1.1
Intermittent access day 15 total infusions	0.2	0.2	0.4	-0.0	-0.2	0.4	-0.6	0.6
Intermittent access terminal intake (last 3 days)	0.8	0.8	1.9	-0.1	-0.5	0.3	-1.4	1.4
Intermittent access total infusions	0.0	0.0	0.1	0.0	-0.4	0.1	-0.2	0.2
Intermittent access day 1 locomotion	2.6	2.6	4.1	-1.2	-1.4	-1.2	2.0	-2.0
Intermittent access day 15 total locomotion	0.4	0.4	1.0	-0.0	-0.1	0.3	1.0	-1.0
Intermittent access total locomotion	0.6	0.6	1.5	0.2	-0.0	0.3	1.2	-1.2
Intermittent access standard deviation	2.1	2.2	2.8	-1.7	-1.5	-0.9	-1.6	1.6
Cocaine induced anxiety	2.5	2.8	5.4	2.1	2.3	2.0	-0.4	0.4
Post-drug Anxiety	0.7	0.8	1.3	0.9	1.1	1.1	-0.5	0.5
Baseline Anxiety	0.4	0.5	0.9	-0.9	-0.9	-0.6	0.4	-0.4
Lifetime Intake	0.0	0.0	0.1	0.1	-0.3	0.1	0.0	-0.0
Incentive Sensitization - Responses	0.3	0.3	0.5	-0.4	-0.5	0.1	-0.7	0.7
Incentive Sensitization - Breakpoint	0.4	0.4	0.7	-0.5	-0.6	0.1	-0.9	0.9
Progressive ratio test 1 active lever presses	0.1	0.1	0.1	-0.1	-0.4	-0.1	0.4	-0.4
Progressive ratio test 1 breakpoint	0.3	0.3	0.5	-0.5	-0.7	-0.5	0.5	-0.5
Progressive ratio test 1 inactive lever presses	3.1	3.3	4.4	2.1	1.8	1.4	1.9	-1.9
Progressive ratio test 2 active lever presses	0.1	0.1	0.3	-0.2	-0.5	-0.0	-0.2	0.2
Progressive ratio test 2 breakpoint	0.2	0.2	0.3	-0.2	-0.5	0.1	-0.5	0.5
Progressive ratio test 2 inactive lever presses	0.2	0.3	0.5	0.4	0.2	0.7	0.6	-0.6
Total sessions with >9 infusions	0.0	0.0	0.1	-0.1	-0.3	-0.1	-0.2	0.2
Short access day 1 total inactive lever presses	2.3	2.6	5.2	2.3	1.9	1.7	0.8	-0.8
Short access day 10 total inactive lever presses	0.3	0.3	0.6	-0.2	0.1	-0.4	0.8	-0.8
Short access day 1 total infusions	0.8	0.9	1.2	-0.6	-1.0	-0.8	1.1	-1.1
Short access day 10 total infusions	0.4	0.4	0.6	-0.4	-0.8	-0.8	0.7	-0.7
Short access total infusions	0.4	0.4	0.8	-0.6	-0.9	-0.8	0.4	-0.4
Short access day 1 locomotion	2.0	2.1	2.6	-1.2	-1.3	-1.5	1.6	-1.6
Short access day 10 total locomotion	3.5	3.9	7.5	-1.2	-1.2	-1.2	2.7	-2.7
Short access total locomotion	3.9	4.0	5.1	-2.2	-2.2	-2.1	1.7	-1.7
Compulsive drug intake	1.2	1.1	2.2	-1.4	-1.2	-1.5	0.1	-0.1
One hour access (0.3 mA shock)	0.2	0.2	0.3	-0.3	-0.6	-0.2	0.5	-0.5
One hour access (shock baseline)	0.2	0.2	0.4	0.5	0.1	0.7	0.4	-0.4
Number of responses in last shaping day	0.2	0.2	0.5	0.1	0.1	-0.2	0.7	-0.7
Context. condit. distance diff. score	2.0	2.4	4.0	-2.0	-1.8	-1.9	-0.7	0.7
Locomotion velocity, session 1	0.3	0.3	0.5	-0.6	-0.7	0.0	-0.6	0.6
Locomotion distance, session 1	1.5	1.9	4.2	-0.2	-0.4	-1.0	2.0	-2.0
Locomotion velocity, session 2	1.0	1.2	2.8	-0.6	-0.4	0.4	-1.7	1.7
Locomotion distance, session 2	0.7	0.9	1.3	-1.2	-0.9	-1.1	0.8	-0.8
Locomotion velocity, session 3	1.0	1.2	2.3	-1.5	-1.1	-1.5	0.3	-0.3
Locomotion distance, session 3	0.5	0.5	1.4	0.6	1.2	0.7	-0.2	0.2
Stereotopy head waving bouts, day 3	0.3	0.4	0.8	-0.8	-0.6	-0.9	0.3	-0.3
Stereotopy head waving duration, day 3	1.4	1.7	3.1	-1.7	-1.7	-1.6	0.2	-0.2
Locomotion velocity, session 7	0.3	0.3	0.5	0.5	0.7	0.6	-0.5	0.5
Locomotion distance, session 7	0.1	0.1	0.2	-0.4	-0.2	-0.3	-0.4	0.4
Stereotopy head waving bouts, day 7	0.8	0.9	1.9	-1.4	-1.3	-0.8	-0.5	0.5
Stereotopy head waving duration, day 7	0.1	0.1	0.2	-0.5	-0.3	-0.3	0.2	-0.2
Locomotion velocity, session 8	1.4	1.7	2.8	-1.7	-1.2	-0.9	-1.3	1.3
Locomotion distance, session 8	4.0	5.9	11.0	-3.3	-3.0	-3.1	-0.2	0.2
Degree of sensitization distance	2.1	2.1	4.2	-1.8	-2.0	-1.6	-0.6	0.6
Degree of sensitization stereotypy	0.0	0.0	0.1	-0.3	-0.3	0.1	-0.2	0.2
Condit. Reinf. active minus inactive responses	1.2	1.4	1.9	1.1	1.3	1.4	-1.0	1.0
Condit. Reinf. active-inactive response ratio	1.4	1.6	3.7	-0.3	-0.1	0.5	-1.9	1.9
Condit. Reinf. active responses	0.6	0.7	1.3	0.9	1.1	1.0	-0.4	0.4
Condit. Reinf. inactive responses	0.6	0.7	1.2	1.0	1.1	0.5	0.8	-0.8
Incentive salience index mean	1.4	1.6	3.2	1.6	1.8	1.5	-0.2	0.2
Condit. Reinf. lever presses	1.1	1.5	1.9	1.2	1.3	0.7	1.4	-1.4
Time in familiar zone, hab. session 1	0.0	0.0	0.0	-0.1	0.1	-0.2	0.0	-0.0
Time in novel zone, hab. session 1	0.3	0.3	0.3	0.6	0.4	0.5	-0.5	0.5
Total zone transitions, hab. session 1	0.0	0.0	0.0	-0.1	0.1	0.1	0.2	-0.2
Total locomotion distance, hab. session 1	0.4	0.6	1.2	0.4	0.4	0.2	1.1	-1.1
Locomotion velocity, hab. session 1	0.2	0.3	0.7	-0.1	-0.1	-0.0	0.8	-0.8
Time in familiar zone, hab. session 2	1.1	1.1	1.9	-1.3	-1.4	-1.4	0.1	-0.1
Time in novel zone, hab. session 2	1.9	1.9	3.0	1.5	1.6	1.7	-0.8	0.8
Total zone transitions, hab. session 2	1.0	1.2	1.6	1.2	1.3	0.9	1.1	-1.1
Total locomotion distance, hab. session 2	0.9	1.2	1.5	1.1	1.2	1.1	0.9	-0.9
Locomotion velocity, hab. session 2	1.3	1.7	1.9	1.4	1.4	1.2	1.3	-1.3
Novel to familiar place preference ratio	0.2	0.2	0.5	0.1	-0.0	0.7	-0.6	0.6
Novelty place preference	0.3	0.3	0.6	0.1	-0.0	0.7	-0.7	0.7
Time in novel zone, NPP test	0.4	0.4	0.7	0.1	0.0	0.8	-0.9	0.9
Total zone transitions, NPP test	0.8	1.1	2.6	-0.2	-0.1	-0.7	1.6	-1.6
Total locomotion distance, NPP test	1.1	1.5	3.7	0.2	0.1	-0.4	1.9	-1.9
Locomotion velocity, NPP test	1.2	1.7	4.1	0.4	0.2	-0.2	2.0	-2.0
Pavlov. Cond. lever latency	0.6	0.7	1.4	0.3	0.3	0.8	-1.2	1.2
Pavlov. Cond. magazine entry latency	0.7	0.9	2.1	-1.2	-0.9	-1.4	0.4	-0.4
Pavlov. Cond. change in total contacts	1.3	1.4	3.3	1.4	1.8	1.3	-0.1	0.1
Pavlov. Cond. index score	0.9	1.2	2.2	-1.1	-0.8	-1.5	0.9	-0.9
Pavlov. Cond. latency score	0.9	1.1	1.9	-0.9	-0.7	-1.4	1.0	-1.0
Pavlov. Cond. lever contacts	0.5	0.5	1.0	-0.4	-0.1	-0.8	1.0	-1.0
Pavlov. Cond. magazine entry number	0.7	0.8	1.7	1.3	0.8	1.3	0.1	-0.1
Pavlov. Cond. intertrial magazine entries	1.4	1.7	3.8	0.9	0.5	0.2	1.9	-1.9
Pavlov. Cond. lever-magazine prob. diff.	1.1	1.3	2.6	-1.2	-0.9	-1.6	1.0	-1.0
Pavlov. Cond. response bias	0.2	0.3	0.6	-0.4	-0.0	-0.8	0.5	-0.5
Bone: apparent density	0.0	0.0	0.1	0.0	0.2	-0.2	0.3	-0.3
Bone surface	0.2	0.3	0.6	0.5	0.8	0.7	-0.4	0.4
Bone volume	0.2	0.4	0.8	0.7	0.9	0.7	-0.2	0.2
Bone: connectivity density	0.1	0.1	0.2	-0.4	-0.2	-0.4	0.0	-0.0
Bone: cortical apparent density	0.4	0.5	0.9	0.9	0.9	0.9	-0.3	0.3
Bone: cortical area	1.8	2.7	5.1	2.3	2.0	2.0	0.5	-0.5
Bone: cortical porosity	0.1	0.1	0.3	0.6	0.4	0.1	0.4	-0.4
Bone: cortical porosity	0.1	0.1	0.2	0.0	-0.2	-0.4	0.3	-0.3
Bone: cortical thickness	1.6	2.6	4.9	2.2	2.1	1.6	0.7	-0.7
Bone: cortical thickness	0.6	0.6	1.2	-0.3	-0.4	-0.8	1.1	-1.1
Bone: cortical tissue density	0.4	0.6	1.0	0.9	0.9	1.0	-0.4	0.4
Bone: elastic displacement	0.3	0.4	0.8	-0.7	-0.7	-0.9	0.1	-0.1
Bone: elastic work	0.3	0.4	0.5	0.7	0.6	-0.0	0.7	-0.7
Bone: endosteal estimation	0.0	0.0	0.1	0.1	-0.0	0.2	-0.1	0.1
Bone: endosteal perimeter	0.3	0.7	0.8	0.9	0.6	0.8	0.8	-0.8
Bone: final force	0.3	0.5	0.9	0.8	0.9	0.9	-0.4	0.4
Bone: final moment	0.4	0.7	1.2	1.0	1.1	1.0	-0.4	0.4
Bone: marrow area	0.0	0.0	0.0	0.0	-0.1	0.1	-0.1	0.1
Bone: maximum diameter	2.6	4.7	8.8	2.7	2.6	3.0	-0.5	0.5
Bone: maximum force	0.2	0.3	0.6	0.7	0.8	0.7	-0.0	0.0
Bone: maximum moment	0.3	0.6	1.0	1.0	1.0	0.9	0.1	-0.1
Bone: minimum diameter	0.1	0.2	0.4	0.1	-0.1	-0.2	0.7	-0.7
Bone: periosteal estimation	0.4	0.9	1.7	1.3	1.1	1.2	0.3	-0.3
Bone: periosteal perimeter	1.0	1.7	2.7	1.7	1.3	1.5	1.0	-1.0
Bone: post-yield work	0.1	0.1	0.2	0.4	0.3	0.5	-0.0	0.0
Bone: stiffness	0.1	0.1	0.2	-0.5	-0.5	-0.1	-0.1	0.1
Bone: tissue strength	1.2	1.2	2.6	-0.6	-0.5	0.2	-1.6	1.6
Bone: trabecular number	0.0	0.0	0.0	0.1	0.1	-0.2	0.0	-0.0
Bone: trabecular spacing	0.5	0.6	1.1	1.1	0.9	1.1	-0.2	0.2
Bone: trabecular thickness	1.0	1.2	1.6	-0.9	-0.8	-1.2	1.2	-1.2
Bone: trabecular tissue density	0.6	0.9	1.8	-1.3	-1.3	-0.5	-0.7	0.7
Breakpoint value in progressive ratio session	0.7	0.8	1.6	1.3	1.0	1.1	0.2	-0.2
Distance traveled before self-admin	0.4	0.5	0.9	0.4	0.4	0.5	-1.0	1.0
Distance traveled after self-admin	0.2	0.2	0.4	0.6	0.6	0.4	0.4	-0.4
Delta time in closed arm before/after self-admin	5.6	5.4	7.9	-2.5	-2.6	-2.8	1.7	-1.7
Delta time in open arm before/after self-admin	5.6	5.3	8.2	2.5	2.6	2.9	-1.6	1.6
Diff in mean of infusions in LGA sessions	0.5	0.5	1.0	-0.3	-0.4	-0.7	1.0	-1.0
Extinction: sum of active levers before priming	0.2	0.2	0.6	0.6	0.4	0.7	0.0	-0.0
Active lever presses in extinction session 6	0.5	0.5	1.1	0.6	0.4	0.0	1.0	-1.0
Delta distance traveled before/after self-admin	1.0	1.1	2.3	-0.4	-0.5	-0.6	1.5	-1.5
Delta ambulatory time before/after self-admin	0.9	1.0	1.9	-0.6	-0.6	-0.7	1.4	-1.4
Time in closed arm before self-admin	0.5	0.5	0.7	0.9	0.7	0.7	-0.7	0.7
Time in closed arm after self-admin	1.3	1.4	2.4	-1.3	-1.6	-1.5	0.6	-0.6
Time in open arm before self-admin	2.2	2.3	4.3	-2.1	-1.7	-1.7	0.9	-0.9
Time in open arm after self-admin	0.1	0.1	0.2	-0.2	0.2	0.4	-0.3	0.3
Sum of active levers in priming session hrs 5-6	1.2	1.2	2.5	1.5	1.6	1.0	0.5	-0.5
Time to tail flick, vehicle, before self-admin	1.9	1.9	4.6	0.2	0.3	-0.3	2.1	-2.1
Time to tail flick, vehicle, after self-admin	0.7	0.8	1.3	0.8	0.8	0.1	1.1	-1.1
Time to tail flick, test, before self-admin	1.7	1.7	3.1	-0.9	-0.9	-0.7	-1.8	1.8
Time to tail flick, test, after self-admin	3.5	3.6	5.4	2.2	2.3	1.6	1.6	-1.6
Delta time to tail flick, vehicle, before/after SA	0.0	0.0	0.1	0.3	-0.0	-0.1	0.1	-0.1
Delta time to tail flick, test, before/after SA	2.7	2.4	3.3	1.5	1.8	1.4	1.5	-1.5
Ambulatory time before self-admin	0.4	0.4	0.8	0.8	0.9	0.7	-0.4	0.4
Ambulatory time after self-admin	0.5	0.5	0.8	0.7	0.6	0.4	0.9	-0.9
Total heroin consumption	0.0	0.1	0.1	0.3	0.3	0.3	-0.1	0.1
Area under the delay curve	2.7	2.9	4.9	2.2	1.7	1.7	1.3	-1.3
Delay disc. indifference point, 0s delay	0.6	0.7	1.7	1.3	1.0	0.8	0.4	-0.4
Delay disc. indifference point, 16s delay	1.4	1.4	2.8	1.7	1.3	1.6	0.2	-0.2
Delay disc. indifference point, 2s delay	2.3	2.6	3.9	2.0	1.6	0.8	1.7	-1.7
Delay disc. indifference point, 24s delay	1.1	1.1	2.0	1.4	1.3	1.2	0.4	-0.4
Delay disc. indifference point, 4s delay	3.2	3.4	5.4	2.3	2.1	1.5	1.6	-1.6
Delay disc. indifference point, 8s delay	1.2	1.2	1.8	1.1	0.7	0.9	1.3	-1.3
Delay discount exponential model param	2.6	2.7	4.5	-2.1	-1.7	-1.6	-1.4	1.4
Delay discount hyperbolic model param	2.8	3.0	5.0	-2.2	-1.8	-1.6	-1.4	1.4
Fecal boli incidents, locomotor time 1	0.1	0.2	0.3	-0.4	-0.2	-0.5	0.4	-0.4
Change in fecal boli incidents, locomotor task	0.9	0.9	1.9	-0.5	-0.3	0.4	-1.4	1.4
Time >=10cm from walls, locomotor time 1	0.4	0.4	1.1	-0.8	-1.0	-0.4	0.1	-0.1
Bouts of movement, locomotor time 1	1.2	1.3	2.9	0.1	0.2	0.9	-1.7	1.7
Total resting periods, locomotor time 1	0.8	0.9	2.0	-0.1	-0.1	0.6	-1.4	1.4
Rest time, locomotor task time 1	0.2	0.3	0.4	-0.5	-0.4	0.1	-0.6	0.6
Distance moved, locomotor task time 1	0.4	0.5	0.7	0.8	0.5	0.4	0.8	-0.8
Vertical activity count, locomotor time 1	0.1	0.2	0.4	0.6	0.2	0.2	0.4	-0.4
Time >=10cm from walls, locomotor time 2	1.4	1.5	2.0	-0.9	-1.4	-1.0	1.3	-1.3
Bouts of movement, locomotor time 2	1.7	1.8	3.9	0.9	0.6	0.1	2.0	-2.0
Total resting periods, locomotor time 2	1.2	1.2	2.5	0.9	0.6	0.2	1.6	-1.6
Rest time, locomotor task time 2	0.5	0.6	1.4	-0.4	-0.3	0.1	-1.2	1.2
Distance moved, locomotor task time 2	0.3	0.3	0.5	-0.5	-0.7	-0.5	0.5	-0.5
Vertical activity count, locomotor time 2	0.5	0.5	0.7	-0.4	-0.8	-0.6	0.9	-0.9
Weight adjusted by age	0.4	0.4	1.0	1.0	0.9	0.5	0.2	-0.2
Seeking ratio, delayed vs. immediate footshock	2.0	2.3	4.6	-0.6	-1.0	-0.9	2.2	-2.2
Locomotion in novel chamber	3.1	3.9	6.7	-2.6	-2.3	-2.6	0.7	-0.7
Locomotion in novel chamber post-restriction	2.3	2.8	4.9	-2.2	-2.0	-2.0	0.7	-0.7
Progressive ratio	0.5	0.6	1.2	-0.2	-0.3	-0.6	1.1	-1.1
Food seeking constrained by brief footshock	3.0	3.7	5.3	1.8	1.8	1.1	2.3	-2.3
Seeking ratio, punishment vs. effort	0.9	1.1	1.9	1.4	1.4	1.2	0.5	-0.5
Run reversals in cocaine runway, females	0.4	0.4	0.6	-0.4	-0.4	-0.7	0.8	-0.8
Run reversals in cocaine runway, males	0.2	0.2	0.4	0.4	0.2	0.6	-0.5	0.5
Latency to leave start box in cocaine runway	0.4	0.4	0.8	0.9	0.9	0.2	0.4	-0.4
Latency to leave start box in cocaine runway, F	1.0	1.1	2.5	1.5	1.6	0.7	0.3	-0.3
Latency to leave start box in cocaine runway, M	0.5	0.5	1.0	-1.0	-0.9	-0.7	0.0	-0.0
Cd content in liver	0.2	0.2	0.3	-0.5	-0.3	-0.6	0.4	-0.4
Co content in liver	0.2	0.3	0.4	0.2	0.5	0.4	-0.7	0.7
Cu content in liver	0.4	0.5	0.7	0.6	0.7	0.8	-0.6	0.6
Fe content in liver	0.2	0.3	0.8	-0.9	-0.6	-0.4	-0.2	0.2
K content in liver	1.6	1.6	2.6	1.2	1.0	0.4	1.6	-1.6
Mg content in liver	0.3	0.3	0.8	0.7	0.9	0.6	0.2	-0.2
Mn content in liver	0.8	1.0	1.8	0.7	0.8	0.2	1.3	-1.3
Na content in liver	2.2	2.4	4.5	1.8	1.8	2.1	-0.7	0.7
Rb content in liver	1.9	2.4	4.6	2.2	1.9	1.8	-0.1	0.1
Se content in liver	1.4	1.7	3.3	1.7	1.8	1.4	0.4	-0.4
Sr content in liver	1.3	1.2	2.1	1.4	1.4	1.3	-0.2	0.2
Zn content in liver	0.7	0.7	0.9	0.9	0.8	0.4	1.0	-1.0