Scn4a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000012134 0.35 0.09 0.0e+00 0.32 0.3 0.33 0.33 1.1e-35 1.8e-33 1.6e-37 5.9e-38
2 Adipose mRNA stability ENSRNOG00000012134 0.03 0.01 1.2e-03 0.01 0.02 0.02 0.01 1.2e-02 9.0e-04 5.5e-03 7.7e-03
3 BLA gene expression ENSRNOG00000012134 0.28 0.08 0.0e+00 0.35 0.38 0.38 0.38 1.3e-19 1.4e-21 2.5e-21 3.2e-21
4 Brain gene expression ENSRNOG00000012134 0.52 0.12 0.0e+00 0.4 0.4 0.39 0.4 2.1e-39 1.3e-39 8.4e-39 5.0e-40
5 LHb gene expression ENSRNOG00000012134 0.54 0.13 3.9e-08 0.18 0.17 0.2 0.18 5.1e-05 7.4e-05 1.6e-05 4.1e-05
6 NAcc gene expression ENSRNOG00000012134 0.32 0.11 0.0e+00 0.32 0.3 0.32 0.32 3.7e-24 4.0e-23 6.1e-24 2.4e-24
7 PL gene expression ENSRNOG00000012134 0.13 0.07 3.5e-09 0.14 0.11 0.14 0.13 1.2e-10 9.4e-09 1.1e-10 3.1e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail0.10.41.0-0.90.3-0.70.2-0.4-0.01.0
BMI without tail1.22.47.10.9-1.20.71.81.31.62.7
Body weight1.98.113.31.8-3.12.03.42.43.13.6
Epididymis fat weight0.81.94.31.1-1.01.31.41.31.32.1
Glucose1.11.62.0-1.41.0-1.1-1.4-1.3-1.3-1.4
Heart weight0.10.10.2-0.5-0.1-0.4-0.3-0.2-0.30.0
Left kidney weight0.51.55.3-1.00.6-2.3-0.7-0.9-1.2-1.0
Right kidney weight0.20.52.7-0.30.1-1.60.2-0.4-0.3-0.3
Tail length2.78.010.22.6-2.82.43.12.72.93.2
Length with tail2.59.212.02.7-3.42.63.52.83.23.0
Length without tail0.51.01.71.0-1.30.91.30.81.00.6
Liver weight, left1.11.72.61.1-1.61.11.51.01.41.3
Liver weight, right0.30.42.2-0.20.3-1.5-0.2-0.5-0.7-0.2
Parametrial fat weight1.63.24.52.1-1.41.12.11.81.72.1
Retroperitoneal fat weight1.75.68.91.7-1.92.03.02.02.72.9
Intraocular pressure0.30.51.30.6-0.50.50.40.90.61.1
Extensor digitorum longus weight1.87.113.1-3.63.2-0.9-2.7-3.4-2.5-0.5
Soleus weight0.20.40.80.6-0.90.00.90.70.50.5
Tibialis anterior weight0.20.62.4-0.40.20.90.3-0.30.51.5
Tibia length0.10.31.20.2-0.7-1.10.70.20.2-0.0
Number of licking bursts0.00.00.1-0.0-0.3-0.1-0.1-0.0-0.0-0.2
Food consumed during 24 hour testing period3.13.76.11.1-1.71.92.31.42.22.5
Times rat made contact with spout1.01.12.50.8-1.00.91.61.01.20.8
Mean time between licks in bursts0.10.10.2-0.2-0.40.20.20.00.10.4
Mean num. licks in bursts0.30.40.80.5-0.20.60.90.50.60.7
Std. dev. time between licks in bursts0.00.00.1-0.20.30.1-0.3-0.2-0.10.2
Water consumed over 24 hours0.10.20.60.3-0.1-0.20.80.30.40.4
Indifference point 0 sec4.26.88.92.5-2.72.22.62.52.73.0
Indifference point AUC1.11.32.10.6-1.21.11.40.61.21.4
Indifference point function ln k0.30.41.10.50.4-1.1-0.80.2-0.6-0.5
Indifference point function log k0.30.41.10.50.4-1.1-0.80.2-0.6-0.5
Delay discounting total patch changes 0 sec4.67.49.12.6-2.92.32.72.72.83.0
Delay discounting total patch changes 12 sec5.06.78.61.8-2.82.92.72.02.82.8
Delay discounting total patch changes 18 sec2.43.23.91.4-2.01.81.91.71.91.6
Delay discounting total patch changes 24 sec4.25.36.52.3-2.51.72.42.32.32.4
Delay discounting total patch changes 6 sec2.64.04.82.0-2.11.62.01.92.02.2
Delay discounting time to switch 0 sec0.20.30.9-0.30.8-0.1-0.6-0.3-0.5-1.0
Delay discounting water rate 0 sec1.72.74.31.5-1.51.01.91.61.62.1
Delay discounting water rate 12 sec0.91.34.2-0.50.9-2.1-0.8-0.6-1.2-1.1
Delay discounting water rate 18 sec0.20.20.90.6-0.3-1.00.20.4-0.1-0.1
Delay discounting water rate 24 sec0.00.00.2-0.1-0.2-0.5-0.0-0.0-0.1-0.2
Delay discounting water rate 6 sec0.20.30.90.8-0.0-0.90.00.6-0.20.2
Locomotor activity0.50.81.80.4-1.00.21.40.71.20.7
Locomotor testing distance1.32.13.11.2-1.51.01.81.61.71.1
Locomotor testing rearing0.91.42.40.7-0.91.51.31.31.60.6
Light reinforcement 10.30.51.80.9-0.40.10.20.50.41.4
Light reinforcement 20.71.02.31.5-0.70.40.61.10.71.4
Reaction time number correct0.50.81.9-0.90.5-1.4-0.7-0.8-1.0-0.6
Reaction time mean minus median0.40.50.9-0.60.9-0.2-1.0-0.6-0.8-0.8
Reaction time mean minus median AUC1.41.82.5-1.21.2-1.2-1.6-1.3-1.4-1.4
Reaction time num false alarms3.44.76.92.1-2.61.72.22.22.32.0
Reaction time num false alarms AUC4.05.67.72.3-2.81.92.42.42.52.3
Reaction time trials correct on left0.50.81.9-0.90.5-1.4-0.7-0.8-1.0-0.6
Reaction time trials on left0.50.71.9-0.80.4-1.4-0.7-0.7-1.0-0.6
Reaction time mean1.01.43.0-0.81.2-0.7-1.4-1.0-1.2-1.7
Reaction time mean AUC1.52.03.8-0.91.5-0.8-1.7-1.1-1.4-2.0
Median of all reaction times1.01.43.2-0.71.1-0.8-1.4-0.9-1.2-1.8
Reaction time omissions0.10.10.40.60.2-0.0-0.20.5-0.3-0.4
Reaction time false alarm rate3.85.46.52.3-2.52.22.32.42.52.0
Reaction time premature initiation rate0.91.21.91.3-0.90.61.11.40.91.2
Reaction time premature initiations0.30.51.00.7-0.7-0.00.70.90.41.0
Std. dev. reaction times0.50.71.1-0.51.0-0.2-1.0-0.7-0.9-1.1
Reaction time trials completed0.50.71.9-0.80.4-1.4-0.7-0.7-1.0-0.6
Reaction time trials AUC0.60.81.9-0.90.5-1.4-0.7-0.8-1.0-0.6
Social response proportion0.30.40.8-0.90.4-0.5-0.6-0.6-0.6-0.4
Social responses0.00.00.1-0.1-0.3-0.00.20.00.30.2
Social time0.10.10.30.2-0.20.40.00.50.1-0.3
Conditioned locomotion0.30.31.10.4-0.51.10.20.50.50.6
Cocaine response after cond. corrected0.30.30.5-0.40.2-0.6-0.7-0.3-0.6-0.7
Cocaine response after cond. not corrected0.40.41.5-0.20.1-0.8-0.6-0.1-0.7-1.2
Cocaine response before conditioning0.10.10.40.5-0.1-0.5-0.00.3-0.1-0.7
Saline control response0.81.12.30.7-0.91.51.00.91.11.0
Condit. Reinf. active minus inactive responses7.39.113.03.4-3.62.13.13.52.92.2
Condit. Reinf. active-inactive response ratio5.15.47.92.8-2.51.72.32.82.21.5
Condit. Reinf. active responses6.99.613.13.4-3.62.63.13.53.02.4
Condit. Reinf. inactive responses1.41.72.41.2-1.51.31.31.31.31.2
Condit. Reinf. lever presses1.82.43.41.7-1.71.11.81.81.60.9
Condit. Reinf. lever reinforcers received6.08.511.33.3-3.42.32.93.32.82.2
Pavlov. Cond. lever latency0.40.51.0-0.81.0-0.4-0.7-0.8-0.7-0.5
Pavlov. Cond. magazine entry latency2.63.03.8-1.91.3-1.5-1.7-1.9-1.8-2.0
Pavlov. Cond. change in total contacts0.30.41.00.3-1.00.80.60.40.70.4
Pavlov. Cond. index score0.00.10.2-0.2-0.3-0.2-0.1-0.0-0.1-0.5
Pavlov. Cond. latency score0.10.10.4-0.2-0.2-0.4-0.2-0.1-0.2-0.7
Pavlov. Cond. lever contacts0.30.40.60.6-0.80.30.70.70.60.5
Pavlov. Cond. magazine entry number3.23.95.22.1-1.61.91.92.02.02.3
Pavlov. Cond. intertrial magazine entries14.418.522.04.3-4.04.34.24.34.34.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.3-0.2-0.3-0.2-0.2-0.3-0.6
Pavlov. Cond. response bias0.00.00.10.0-0.4-0.10.20.10.0-0.1
Conditioned reinforcement - actives0.80.81.00.6-0.90.81.00.71.01.0
Conditioned reinforcement - inactives1.31.51.91.1-1.20.81.41.21.31.4
Conditioned locomotion3.03.64.21.8-1.91.62.02.02.02.0
Intermittent access intake day 1-15 change0.20.21.10.1-0.21.00.50.30.50.0
Intermittent access intake escalation0.10.10.4-0.20.20.60.2-0.00.2-0.2
Intermittent access intake escalation 20.60.61.60.5-0.41.30.90.60.90.5
Intermitt. access day 1 inactive lever presses5.15.57.22.7-2.71.82.32.62.41.7
Intermitt. access day 15 inactive lever presses2.73.05.62.4-1.21.41.52.31.61.3
Intermitt. access escalation Index3.53.14.0-2.01.2-1.5-1.9-1.9-1.8-1.9
Intermittent access day 1 total infusions1.01.12.10.9-1.20.41.01.01.01.5
Intermittent access day 15 total infusions0.60.61.30.3-0.70.81.00.50.91.2
Intermittent access terminal intake (last 3 days)2.73.03.91.4-1.61.71.91.61.82.0
Intermittent access total infusions3.33.75.11.6-2.01.52.11.72.12.3
Intermittent access day 1 locomotion4.95.07.02.1-2.31.42.42.32.32.6
Intermittent access day 15 total locomotion6.36.79.22.1-2.52.23.02.32.92.9
Intermittent access total locomotion9.510.713.83.0-3.12.53.73.23.53.7
Intermittent access standard deviation1.71.92.71.4-0.91.11.71.41.51.5
Cocaine induced anxiety0.20.20.80.50.3-0.9-0.30.3-0.5-0.3
Post-drug Anxiety0.30.30.80.20.5-0.9-0.50.1-0.7-0.5
Baseline Anxiety0.80.80.9-0.90.9-1.0-0.9-0.9-1.0-0.8
Lifetime Intake3.84.35.51.9-2.11.52.22.02.22.3
Incentive Sensitization - Responses4.24.24.71.9-2.22.02.22.02.02.0
Incentive Sensitization - Breakpoint3.93.94.61.8-2.11.92.12.02.01.9
Progressive ratio test 1 active lever presses5.45.57.12.3-2.71.72.52.42.42.5
Progressive ratio test 1 breakpoint6.66.88.42.5-2.92.12.72.72.72.7
Progressive ratio test 1 inactive lever presses5.25.57.82.3-2.81.82.32.42.42.3
Progressive ratio test 2 active lever presses6.46.87.72.6-2.72.22.82.72.62.7
Progressive ratio test 2 breakpoint7.38.28.92.8-3.02.43.03.02.92.9
Progressive ratio test 2 inactive lever presses5.46.28.62.3-2.52.02.62.42.62.9
Total sessions with >9 infusions0.30.30.80.3-0.6-0.30.60.30.50.9
Short access day 1 total inactive lever presses1.11.21.61.2-1.20.41.31.31.21.1
Short access day 10 total inactive lever presses0.50.60.80.8-0.60.90.60.70.80.9
Short access day 1 total infusions1.01.11.80.9-1.20.31.01.01.11.3
Short access day 10 total infusions6.67.28.82.6-2.62.22.82.72.93.0
Short access total infusions3.63.94.62.1-2.11.32.02.12.22.1
Short access day 1 locomotion3.73.96.11.9-2.01.22.02.12.12.5
Short access day 10 total locomotion12.413.516.93.2-3.43.34.13.54.04.1
Short access total locomotion5.96.08.02.2-2.31.82.72.42.72.8
Compulsive drug intake1.11.11.9-0.80.7-1.4-1.0-0.8-1.1-1.4
One hour access (0.3 mA shock)1.01.21.70.9-1.31.11.01.11.20.9
One hour access (shock baseline)1.61.82.50.9-1.21.61.41.11.51.5
Number of responses in last shaping day1.01.12.11.3-1.10.40.91.40.90.7
Context. condit. distance diff. score0.30.31.0-1.00.4-0.2-0.4-0.9-0.40.0
Locomotion velocity, session 11.61.72.71.6-1.10.61.71.51.31.0
Locomotion distance, session 10.10.20.70.4-0.3-0.30.80.40.30.3
Locomotion velocity, session 20.50.61.01.0-0.80.70.81.00.9-0.2
Locomotion distance, session 20.00.10.2-0.1-0.3-0.20.4-0.10.3-0.3
Locomotion velocity, session 30.30.41.3-0.20.4-1.1-0.3-0.4-0.6-0.7
Locomotion distance, session 30.10.10.10.3-0.4-0.30.20.20.0-0.4
Stereotopy head waving bouts, day 30.20.20.70.20.6-0.8-0.4-0.2-0.5-0.1
Stereotopy head waving duration, day 30.20.30.5-0.30.4-0.7-0.6-0.5-0.6-0.0
Locomotion velocity, session 70.30.30.6-0.40.8-0.6-0.3-0.6-0.5-0.6
Locomotion distance, session 70.00.10.1-0.30.2-0.0-0.3-0.3-0.2-0.2
Stereotopy head waving bouts, day 70.30.40.8-0.10.5-0.9-0.6-0.3-0.6-0.8
Stereotopy head waving duration, day 71.41.72.8-1.01.2-1.3-1.3-1.3-1.3-1.7
Locomotion velocity, session 80.60.71.1-0.1-0.81.01.00.11.10.9
Locomotion distance, session 80.10.10.3-0.6-0.10.20.1-0.60.10.2
Degree of sensitization distance0.20.20.5-0.4-0.20.70.2-0.20.40.7
Degree of sensitization stereotypy1.11.22.5-0.80.9-1.2-0.9-0.9-0.9-1.6
Condit. Reinf. active minus inactive responses2.83.24.31.9-1.91.71.72.11.81.3
Condit. Reinf. active-inactive response ratio1.31.42.01.3-1.21.10.91.41.20.9
Condit. Reinf. active responses3.54.24.92.1-2.22.12.02.22.11.8
Condit. Reinf. inactive responses1.11.31.81.1-1.31.01.21.01.11.3
Incentive salience index mean3.03.74.92.2-1.91.62.02.21.91.3
Condit. Reinf. lever presses0.50.71.11.0-0.70.61.00.80.90.3
Time in familiar zone, hab. session 10.60.62.2-0.1-0.71.50.60.10.80.8
Time in novel zone, hab. session 11.21.23.0-0.21.1-1.7-1.1-0.3-1.2-1.2
Total zone transitions, hab. session 10.20.31.0-0.1-0.4-0.11.00.00.70.6
Total locomotion distance, hab. session 11.11.53.41.3-0.90.11.81.21.41.1
Locomotion velocity, hab. session 11.52.14.41.4-1.20.52.11.31.61.4
Time in familiar zone, hab. session 21.11.22.60.3-1.21.61.00.51.31.1
Time in novel zone, hab. session 21.21.22.9-0.11.1-1.7-0.9-0.3-1.3-1.1
Total zone transitions, hab. session 20.10.10.2-0.5-0.10.10.4-0.40.30.3
Total locomotion distance, hab. session 20.40.61.40.4-0.50.41.20.30.91.1
Locomotion velocity, hab. session 20.40.61.40.4-0.50.41.20.20.81.2
Novel to familiar place preference ratio0.40.40.70.8-0.60.20.60.80.60.6
Novelty place preference0.20.20.40.6-0.40.00.30.60.30.3
Time in novel zone, NPP test0.10.10.30.6-0.3-0.10.20.50.20.1
Total zone transitions, NPP test0.10.10.4-0.1-0.3-0.50.7-0.20.30.3
Total locomotion distance, NPP test0.71.02.50.9-0.80.21.60.81.11.0
Locomotion velocity, NPP test0.50.71.60.6-0.60.21.30.50.81.1
Pavlov. Cond. lever latency2.73.45.1-2.21.8-1.0-2.3-2.0-2.0-1.2
Pavlov. Cond. magazine entry latency4.25.47.02.6-2.41.82.52.62.51.7
Pavlov. Cond. change in total contacts3.43.75.52.3-1.81.52.02.22.01.3
Pavlov. Cond. index score3.74.86.32.5-2.31.52.42.42.31.6
Pavlov. Cond. latency score3.03.94.92.2-2.11.32.22.12.11.5
Pavlov. Cond. lever contacts2.12.53.61.8-1.51.11.91.71.81.0
Pavlov. Cond. magazine entry number3.34.26.5-2.52.1-1.5-2.1-2.3-2.1-1.6
Pavlov. Cond. intertrial magazine entries0.60.81.60.3-1.11.10.70.50.71.3
Pavlov. Cond. lever-magazine prob. diff.3.44.25.92.4-2.21.42.22.32.21.5
Pavlov. Cond. response bias4.55.59.03.0-2.31.52.52.82.41.5
Bone: apparent density2.33.88.12.8-1.70.72.02.41.71.5
Bone surface7.713.518.54.3-3.92.54.04.23.62.7
Bone volume6.410.816.04.0-3.42.13.43.83.22.6
Bone: connectivity density3.14.98.73.0-2.11.22.32.72.11.6
Bone: cortical apparent density4.55.87.7-2.02.7-2.8-2.4-2.5-2.6-1.7
Bone: cortical area2.23.45.82.4-2.00.32.02.31.61.6
Bone: cortical porosity9.910.717.23.9-3.32.53.34.13.31.9
Bone: cortical porosity6.06.410.53.0-2.71.52.63.22.51.5
Bone: cortical thickness3.15.215.3-0.92.3-3.9-1.8-1.4-2.5-1.9
Bone: cortical thickness3.33.88.8-0.82.0-3.0-1.8-1.1-2.1-2.2
Bone: cortical tissue density4.35.67.3-2.02.7-2.7-2.4-2.5-2.5-1.7
Bone: elastic displacement1.21.43.8-0.71.2-1.9-0.8-0.9-1.1-1.2
Bone: elastic work0.30.40.80.9-0.0-0.70.80.70.40.3
Bone: endosteal estimation16.134.840.15.6-6.36.06.06.26.24.9
Bone: endosteal perimeter18.337.547.35.6-6.95.96.26.36.45.5
Bone: final force1.21.93.21.8-1.6-0.11.71.61.11.0
Bone: final moment1.32.13.71.9-1.6-0.01.81.71.21.1
Bone: marrow area15.833.938.95.5-6.25.95.96.16.14.8
Bone: maximum diameter6.111.215.33.8-3.92.43.33.93.22.7
Bone: maximum force2.13.64.92.1-2.20.52.22.21.71.7
Bone: maximum moment2.23.95.32.3-2.20.62.32.31.81.8
Bone: minimum diameter14.927.632.05.1-5.74.65.55.55.44.9
Bone: periosteal estimation11.623.629.95.2-5.33.95.05.54.94.1
Bone: periosteal perimeter6.811.215.73.6-4.02.13.53.83.32.8
Bone: post-yield work2.53.44.51.5-2.11.62.11.82.01.5
Bone: stiffness0.81.22.90.8-1.70.61.30.91.11.0
Bone: tissue strength1.31.21.9-1.30.7-1.4-0.9-1.2-1.1-1.2
Bone: trabecular number3.25.09.03.0-2.31.12.32.72.11.6
Bone: trabecular spacing1.11.53.7-1.91.1-0.2-1.2-1.7-0.9-0.7
Bone: trabecular thickness4.15.09.73.1-2.01.12.22.91.91.8
Bone: trabecular tissue density0.91.33.7-0.70.8-1.9-0.9-0.8-1.4-0.8
Breakpoint value in progressive ratio session0.70.81.20.9-1.01.10.81.00.90.3
Distance traveled before self-admin0.50.51.3-0.5-0.1-0.6-0.9-0.2-0.8-1.1
Distance traveled after self-admin0.30.31.2-0.5-0.4-0.2-0.6-0.2-0.3-1.1
Delta time in closed arm before/after self-admin0.00.00.10.1-0.20.00.40.10.3-0.2
Delta time in open arm before/after self-admin0.50.50.9-0.80.8-0.2-0.9-0.8-0.8-0.1
Diff in mean of infusions in LGA sessions1.11.21.6-1.21.3-1.0-1.1-1.1-1.1-1.0
Extinction: sum of active levers before priming0.20.20.6-0.0-0.50.80.20.20.40.5
Active lever presses in extinction session 62.32.23.11.7-1.41.51.41.81.51.1
Delta distance traveled before/after self-admin0.20.20.4-0.40.5-0.5-0.4-0.4-0.3-0.6
Delta ambulatory time before/after self-admin0.00.00.10.1-0.10.10.30.00.2-0.1
Time in closed arm before self-admin0.81.02.1-0.61.1-1.5-0.7-0.8-0.8-1.1
Time in closed arm after self-admin0.60.61.1-0.90.7-0.9-0.4-0.9-0.5-1.1
Time in open arm before self-admin0.40.50.9-0.70.5-0.6-0.7-0.6-0.7-1.0
Time in open arm after self-admin0.10.10.3-0.2-0.10.5-0.20.1-0.10.5
Sum of active levers in priming session hrs 5-60.50.41.0-0.70.4-0.1-1.0-0.7-0.7-0.6
Time to tail flick, vehicle, before self-admin0.20.20.50.0-0.2-0.4-0.30.1-0.5-0.7
Time to tail flick, vehicle, after self-admin0.80.91.31.0-1.10.90.61.00.51.1
Time to tail flick, test, before self-admin0.80.81.1-1.11.1-0.2-0.8-0.9-0.8-1.0
Time to tail flick, test, after self-admin0.10.10.20.20.2-0.5-0.4-0.0-0.4-0.2
Delta time to tail flick, vehicle, before/after SA2.62.54.21.7-1.11.71.51.41.52.0
Delta time to tail flick, test, before/after SA0.10.10.20.5-0.4-0.2-0.00.10.10.4
Ambulatory time before self-admin0.20.20.5-0.3-0.3-0.4-0.6-0.1-0.4-0.7
Ambulatory time after self-admin0.10.10.40.2-0.60.00.10.40.1-0.5
Total heroin consumption0.50.61.20.9-1.10.50.61.00.6-0.1
Area under the delay curve0.10.10.30.4-0.5-0.00.40.30.20.5
Delay disc. indifference point, 0s delay0.60.61.2-0.60.6-0.6-1.1-0.8-1.0-0.6
Delay disc. indifference point, 16s delay0.30.30.60.7-0.80.20.40.70.30.5
Delay disc. indifference point, 2s delay0.80.91.71.0-1.30.50.90.70.71.2
Delay disc. indifference point, 24s delay1.91.83.01.1-1.50.91.51.21.41.7
Delay disc. indifference point, 4s delay0.50.51.0-0.40.5-1.0-0.7-0.5-0.9-1.0
Delay disc. indifference point, 8s delay0.10.10.40.10.2-0.6-0.2-0.1-0.30.1
Delay discount exponential model param0.30.40.6-0.50.8-0.3-0.7-0.5-0.5-0.8
Delay discount hyperbolic model param0.20.20.5-0.50.7-0.1-0.5-0.4-0.4-0.7
Fecal boli incidents, locomotor time 10.10.10.1-0.3-0.10.3-0.3-0.1-0.2-0.4
Change in fecal boli incidents, locomotor task0.30.30.5-0.70.6-0.6-0.3-0.5-0.5-0.3
Time >=10cm from walls, locomotor time 13.23.24.6-1.91.2-1.6-1.9-1.7-1.8-2.1
Bouts of movement, locomotor time 10.30.41.2-0.31.1-0.6-0.6-0.5-0.6-0.1
Total resting periods, locomotor time 10.40.41.3-0.31.1-0.6-0.6-0.5-0.7-0.2
Rest time, locomotor task time 10.20.20.40.10.6-0.2-0.5-0.1-0.5-0.6
Distance moved, locomotor task time 10.80.81.60.6-0.80.61.20.61.11.3
Vertical activity count, locomotor time 10.50.51.00.6-0.70.21.00.60.80.7
Time >=10cm from walls, locomotor time 20.10.20.6-0.00.3-0.3-0.40.1-0.3-0.8
Bouts of movement, locomotor time 20.40.51.0-0.30.9-0.4-1.0-0.4-0.9-0.5
Total resting periods, locomotor time 20.91.01.7-0.61.1-0.7-1.3-0.7-1.2-0.9
Rest time, locomotor task time 24.24.97.7-1.92.0-1.7-2.8-2.1-2.5-2.2
Distance moved, locomotor task time 20.91.12.11.0-0.50.71.50.91.21.0
Vertical activity count, locomotor time 23.74.05.52.3-1.51.62.42.22.21.8
Weight adjusted by age0.91.01.4-1.20.6-0.6-1.2-1.1-1.1-1.0
Seeking ratio, delayed vs. immediate footshock0.10.10.2-0.40.20.20.3-0.10.10.3
Locomotion in novel chamber0.10.10.3-0.3-0.5-0.20.3-0.10.0-0.5
Locomotion in novel chamber post-restriction2.32.74.41.6-2.11.41.31.61.51.8
Progressive ratio0.00.00.1-0.2-0.20.1-0.0-0.3-0.10.2
Food seeking constrained by brief footshock3.64.46.91.4-1.92.62.51.62.42.0
Seeking ratio, punishment vs. effort1.11.41.91.0-1.01.41.41.21.40.8
Run reversals in cocaine runway, females0.40.41.6-0.21.3-0.7-0.4-0.3-0.5-0.2
Run reversals in cocaine runway, males0.20.20.3-0.10.1-0.4-0.6-0.0-0.5-0.5
Latency to leave start box in cocaine runway0.40.40.7-0.50.6-0.7-0.7-0.4-0.8-0.8
Latency to leave start box in cocaine runway, F0.91.01.9-0.70.6-1.4-1.0-0.6-1.1-1.3
Latency to leave start box in cocaine runway, M0.10.10.2-0.20.40.40.1-0.1-0.00.1
Cd content in liver3.94.36.5-2.52.1-1.3-2.0-2.5-2.0-1.7
Co content in liver0.70.81.6-1.30.90.0-0.8-1.3-0.5-0.6
Cu content in liver0.30.40.90.9-0.20.70.20.80.40.5
Fe content in liver0.30.40.8-0.30.4-0.4-0.9-0.4-0.7-0.9
K content in liver1.01.02.21.0-1.51.10.70.81.10.7
Mg content in liver0.10.10.60.2-0.20.8-0.2-0.20.20.3
Mn content in liver0.10.10.40.6-0.6-0.10.20.20.2-0.1
Na content in liver0.40.51.40.8-1.20.70.20.50.60.4
Rb content in liver3.24.04.9-1.91.7-1.6-2.2-2.2-2.1-2.2
Se content in liver1.41.72.9-1.40.8-1.0-1.7-1.6-1.4-1.0
Sr content in liver0.60.50.80.9-0.8-0.00.90.90.70.6
Zn content in liver0.20.20.80.6-0.9-0.20.20.30.30.5