# | tissue | modality | RNA phenotype | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | LASSO R2 | eQTL P | BLUP P | ENET P | LASSO P |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | gene expression | ENSRNOG00000011979 | 0.0270 | 0.0270 | 6.7e-03 | 0.017 | 0.007 | 0.008 | 0.009 | 4.6e-03 | 4.4e-02 | 4.3e-02 | 3.1e-02 |
2 | BLA | gene expression | ENSRNOG00000011979 | 0.1200 | 0.0955 | 1.8e-03 | 0.064 | 0.017 | 0.037 | 0.054 | 2.4e-04 | 4.1e-02 | 4.3e-03 | 7.1e-04 |
3 | BLA | isoform ratio | ENSRNOT00000016207 | 0.0620 | 0.0480 | 2.6e-03 | 0.029 | 0.033 | 0.025 | 0.023 | 1.0e-02 | 6.9e-03 | 1.6e-02 | 2.0e-02 |
4 | Brain | alternative TSS | ENSRNOT00000016207 | 0.1358 | 0.1036 | 5.6e-09 | 0.088 | 0.092 | 0.086 | 0.089 | 1.5e-08 | 7.5e-09 | 2.3e-08 | 1.3e-08 |
5 | Brain | gene expression | ENSRNOG00000011979 | 0.0500 | 0.0330 | 2.9e-06 | 0.044 | 0.048 | 0.045 | 0.040 | 5.7e-05 | 3.0e-05 | 4.9e-05 | 1.3e-04 |
6 | Brain | isoform ratio | ENSRNOT00000110868 | 0.0386 | 0.0381 | 4.3e-03 | 0.026 | 0.018 | 0.020 | 0.018 | 1.8e-03 | 7.0e-03 | 5.1e-03 | 7.5e-03 |
7 | Brain | intron excision ratio | chr14:80585233:80588606 | 0.1309 | 0.0976 | 4.9e-08 | 0.078 | 0.080 | 0.082 | 0.081 | 1.0e-07 | 6.5e-08 | 5.1e-08 | 6.2e-08 |
8 | Brain | intron excision ratio | chr14:80588528:80588606 | 0.0579 | 0.0490 | 1.1e-05 | 0.056 | 0.044 | 0.053 | 0.043 | 5.8e-06 | 6.0e-05 | 1.1e-05 | 7.5e-05 |
9 | LHb | gene expression | ENSRNOG00000011979 | 0.2206 | 0.1320 | 1.4e-04 | 0.161 | 0.152 | 0.129 | 0.133 | 1.2e-04 | 1.9e-04 | 5.8e-04 | 4.9e-04 |
10 | Liver | gene expression | ENSRNOG00000011979 | 0.0800 | 0.0420 | 4.4e-14 | 0.107 | 0.106 | 0.099 | 0.094 | 6.6e-12 | 9.0e-12 | 4.6e-11 | 1.5e-10 |
11 | Liver | isoform ratio | ENSRNOT00000016207 | 0.0312 | 0.0249 | 1.3e-03 | 0.007 | 0.015 | 0.010 | 0.009 | 4.6e-02 | 8.2e-03 | 2.3e-02 | 3.1e-02 |
12 | Liver | isoform ratio | ENSRNOT00000110868 | 0.0380 | 0.0290 | 2.7e-04 | 0.023 | 0.025 | 0.014 | 0.020 | 1.1e-03 | 6.9e-04 | 9.9e-03 | 2.6e-03 |
13 | Liver | intron excision ratio | chr14:80585233:80588417 | 0.0489 | 0.0318 | 5.5e-06 | 0.034 | 0.036 | 0.031 | 0.031 | 9.4e-05 | 6.7e-05 | 1.9e-04 | 1.9e-04 |
14 | Liver | intron excision ratio | chr14:80588528:80588606 | 0.0588 | 0.0359 | 1.2e-07 | 0.042 | 0.052 | 0.046 | 0.045 | 1.6e-05 | 2.0e-06 | 6.7e-06 | 9.2e-06 |
15 | PL2 | isoform ratio | ENSRNOT00000016207 | 0.0957 | 0.0710 | 1.6e-04 | 0.048 | 0.062 | 0.046 | 0.048 | 1.3e-03 | 2.8e-04 | 1.7e-03 | 1.2e-03 |
16 | PL2 | isoform ratio | ENSRNOT00000110868 | 0.1370 | 0.1281 | 3.5e-04 | 0.056 | 0.054 | 0.058 | 0.059 | 5.4e-04 | 7.0e-04 | 4.2e-04 | 3.9e-04 |
17 | PL2 | intron excision ratio | chr14:80585233:80588606 | 0.1000 | 0.0970 | 2.0e-03 | 0.040 | 0.042 | 0.028 | 0.028 | 3.0e-03 | 2.4e-03 | 1.2e-02 | 1.1e-02 |
All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method.
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
dissection: UMAP 1 of all traits | 0.2 | 0.8 | 2.6 | 0.7 | 1.6 | -1.3 | 0.8 | 0.9 | 0.9 | 0.6 | -0.9 | 0.8 | 0.9 | -0.6 | 0.6 | 0.6 | -0.6 | -0.9 | 1.1 | 1.0 |
retroperitoneal_fat_g | 0.0 | 0.0 | 0.1 | 0.3 | -0.4 | 0.3 | 0.0 | -0.0 | 0.1 | 0.1 | 0.0 | 0.1 | -0.0 | -0.2 | 0.2 | 0.2 | -0.2 | -0.0 | -0.1 | -0.1 |
body_g | 1.2 | 5.2 | 7.7 | -2.2 | -2.8 | 2.6 | -2.2 | -2.4 | -2.3 | -1.9 | 2.3 | -2.2 | -2.3 | 2.0 | -2.1 | -2.1 | 2.1 | 2.3 | -2.5 | -2.4 |
dissection: UMAP 3 of all traits | 0.8 | 2.2 | 4.5 | 1.8 | 2.1 | -1.8 | 1.2 | 1.5 | 1.6 | 1.1 | -1.4 | 1.4 | 1.3 | -1.3 | 1.3 | 1.3 | -1.3 | -1.5 | 1.6 | 1.5 |
kidney_right_g | 1.0 | 2.8 | 3.7 | 1.7 | 0.3 | -1.3 | 1.8 | 1.7 | 1.6 | 1.9 | -1.6 | 1.6 | 1.6 | -1.9 | 1.9 | 1.9 | -1.9 | -1.7 | 1.5 | 1.6 |
dissection: PC 3 of all traits | 0.7 | 1.8 | 2.7 | 1.2 | 1.6 | -1.4 | 1.3 | 1.3 | 1.4 | 1.4 | -1.4 | 1.5 | 1.4 | -1.1 | 1.1 | 1.1 | -1.2 | -1.3 | 1.5 | 1.4 |
dissection: PC 2 of all traits | 0.3 | 0.8 | 2.0 | -1.4 | -1.2 | 1.1 | -0.6 | -0.9 | -1.0 | -0.6 | 0.7 | -0.8 | -0.7 | 0.8 | -0.9 | -0.8 | 0.8 | 0.9 | -0.9 | -0.8 |
glucose_mg_dl | 17.3 | 26.3 | 36.2 | -5.9 | -0.9 | 4.1 | -5.0 | -5.2 | -5.3 | -4.8 | 5.0 | -5.0 | -5.0 | 6.0 | -6.0 | -5.9 | 5.8 | 5.4 | -4.7 | -5.0 |
heart_g | 0.2 | 0.3 | 1.8 | 0.4 | 1.3 | -0.8 | 0.3 | 0.5 | 0.2 | -0.0 | -0.4 | 0.3 | 0.4 | -0.3 | 0.3 | 0.3 | -0.3 | -0.5 | 0.5 | 0.5 |
os_mean | 0.8 | 1.0 | 1.5 | -1.0 | 0.1 | 0.8 | -1.1 | -1.0 | -0.8 | -0.7 | 1.1 | -1.0 | -1.1 | 1.2 | -1.2 | -1.2 | 1.2 | 1.1 | -1.0 | -1.1 |
EDL weight in grams | 3.2 | 12.8 | 13.7 | -3.7 | -3.0 | 3.6 | -3.6 | -3.7 | -3.7 | -3.5 | 3.6 | -3.6 | -3.6 | 3.5 | -3.6 | -3.6 | 3.6 | 3.6 | -3.7 | -3.6 |
Tibia length in mm | 0.1 | 0.4 | 0.8 | 0.6 | -0.9 | -0.1 | 0.7 | 0.5 | 0.5 | 0.6 | -0.6 | 0.6 | 0.6 | -0.8 | 0.8 | 0.8 | -0.7 | -0.6 | 0.4 | 0.5 |
sol weight in grams | 0.5 | 1.5 | 5.0 | -1.3 | -2.2 | 1.6 | -0.9 | -1.2 | -1.2 | -0.8 | 1.1 | -1.1 | -1.0 | 1.0 | -1.0 | -1.0 | 1.0 | 1.2 | -1.3 | -1.2 |
TA weight in grams | 1.2 | 4.0 | 4.5 | -2.0 | -1.2 | 1.9 | -2.0 | -2.0 | -2.0 | -1.9 | 2.1 | -2.0 | -2.1 | 2.1 | -2.1 | -2.1 | 2.1 | 2.1 | -2.1 | -2.0 |
Average time between licks in bursts | 0.5 | 0.7 | 1.4 | -1.2 | -0.2 | 0.5 | -0.7 | -0.8 | -1.1 | -1.0 | 0.7 | -0.7 | -0.7 | 1.1 | -1.1 | -1.0 | 1.0 | 0.9 | -0.6 | -0.7 |
Std. dev. time between licks in bursts | 0.0 | 0.0 | 0.3 | -0.1 | -0.1 | -0.0 | -0.2 | -0.1 | -0.4 | -0.5 | 0.2 | -0.2 | -0.2 | 0.2 | -0.2 | -0.2 | 0.2 | 0.1 | -0.1 | -0.1 |
Number of licking bursts | 2.8 | 3.4 | 4.0 | -2.0 | -1.5 | 1.9 | -1.8 | -1.9 | -1.9 | -1.7 | 1.8 | -1.8 | -1.8 | 1.8 | -1.9 | -1.8 | 1.9 | 1.9 | -1.9 | -1.8 |
Food consumed during 24 hour testing period | 2.3 | 2.8 | 3.8 | -1.9 | -0.5 | 1.4 | -1.7 | -1.7 | -1.7 | -1.8 | 1.7 | -1.7 | -1.7 | 1.8 | -1.8 | -1.8 | 1.8 | 1.7 | -1.6 | -1.6 |
Water consumed over 24 hour session | 1.6 | 1.9 | 2.7 | -1.6 | -0.1 | 1.0 | -1.4 | -1.3 | -1.5 | -1.6 | 1.3 | -1.3 | -1.3 | 1.6 | -1.6 | -1.6 | 1.5 | 1.4 | -1.2 | -1.3 |
Times rat made contact with spout | 0.4 | 0.4 | 3.5 | -0.6 | 1.9 | -0.6 | -0.3 | -0.1 | -0.5 | -0.6 | 0.2 | -0.2 | -0.2 | 0.8 | -0.8 | -0.8 | 0.7 | 0.3 | 0.1 | -0.0 |
Average drop size | 0.6 | 0.7 | 2.9 | -0.6 | -1.7 | 1.2 | -0.8 | -0.8 | -0.6 | -0.6 | 0.8 | -0.8 | -0.8 | 0.3 | -0.3 | -0.4 | 0.4 | 0.7 | -1.0 | -0.9 |
light_reinforcement_lr_relactive | 0.1 | 0.1 | 1.1 | -0.1 | -1.1 | 0.5 | 0.2 | -0.0 | 0.2 | 0.5 | -0.0 | 0.0 | 0.1 | -0.3 | 0.3 | 0.3 | -0.3 | -0.1 | -0.1 | 0.0 |
light_reinforcement_lr_active | 0.1 | 0.1 | 0.3 | -0.3 | -0.3 | 0.5 | -0.4 | -0.4 | -0.4 | -0.4 | 0.4 | -0.4 | -0.4 | 0.2 | -0.2 | -0.2 | 0.3 | 0.4 | -0.4 | -0.4 |
Delay discounting water rate 0 sec | 2.2 | 3.5 | 4.4 | -1.7 | -0.7 | 1.6 | -2.1 | -1.9 | -2.0 | -2.1 | 2.0 | -1.9 | -1.9 | 2.0 | -1.9 | -2.0 | 2.0 | 1.9 | -2.0 | -1.9 |
Median of all reaction times | 0.4 | 0.6 | 1.1 | 0.8 | 0.1 | -0.6 | 0.8 | 0.8 | 0.9 | 1.0 | -0.6 | 0.7 | 0.6 | -0.8 | 0.8 | 0.8 | -0.8 | -0.7 | 0.6 | 0.7 |
locomotor_testing_activity | 0.5 | 0.8 | 1.6 | -1.1 | -0.1 | 0.5 | -0.9 | -0.9 | -0.7 | -0.3 | 0.8 | -0.8 | -0.9 | 1.3 | -1.3 | -1.2 | 1.2 | 1.0 | -0.7 | -0.8 |
reaction_time_corr | 0.1 | 0.2 | 0.5 | -0.3 | 0.7 | 0.1 | -0.4 | -0.3 | -0.2 | -0.4 | 0.4 | -0.3 | -0.4 | 0.4 | -0.4 | -0.4 | 0.4 | 0.4 | -0.3 | -0.3 |
reaction_time_leftcorr | 0.1 | 0.2 | 0.5 | -0.3 | 0.7 | 0.1 | -0.4 | -0.3 | -0.2 | -0.4 | 0.4 | -0.3 | -0.4 | 0.4 | -0.4 | -0.4 | 0.4 | 0.4 | -0.3 | -0.3 |
delay_discounting_pc1800 | 2.3 | 3.0 | 4.1 | -1.6 | 0.1 | 1.2 | -1.8 | -1.7 | -1.9 | -1.9 | 1.8 | -1.8 | -1.7 | 2.0 | -2.0 | -2.0 | 2.0 | 1.8 | -1.7 | -1.7 |
reaction_time_falsealarm | 0.5 | 0.7 | 2.0 | -0.2 | -1.4 | 1.0 | -1.0 | -0.7 | -0.9 | -1.3 | 0.8 | -1.0 | -0.8 | 0.3 | -0.3 | -0.4 | 0.5 | 0.6 | -0.9 | -0.9 |
social_reinforcement_socialrfq | 1.7 | 1.9 | 2.9 | -1.7 | -1.3 | 1.5 | -1.2 | -1.5 | -1.4 | -1.2 | 1.2 | -1.3 | -1.2 | 1.4 | -1.4 | -1.4 | 1.4 | 1.4 | -1.3 | -1.4 |
reaction_time_pinit | 1.3 | 1.8 | 2.1 | 1.4 | 1.0 | -1.4 | 1.3 | 1.4 | 1.4 | 1.3 | -1.3 | 1.4 | 1.3 | -1.4 | 1.4 | 1.4 | -1.4 | -1.4 | 1.4 | 1.4 |
reaction_time_pinit_slope | 1.4 | 1.9 | 2.4 | -1.5 | -1.3 | 1.5 | -1.2 | -1.4 | -1.4 | -1.2 | 1.3 | -1.4 | -1.3 | 1.4 | -1.4 | -1.3 | 1.4 | 1.4 | -1.4 | -1.4 |
reaction_time_peropfalsealarm_slope | 0.1 | 0.2 | 1.9 | -0.1 | 1.4 | -0.5 | 0.2 | 0.2 | 0.1 | 0.3 | -0.2 | 0.3 | 0.2 | 0.3 | -0.2 | -0.2 | 0.2 | -0.1 | 0.3 | 0.3 |
soc_socialavgti | 0.4 | 0.5 | 1.3 | -0.5 | -1.1 | 1.0 | -0.7 | -0.7 | -0.6 | -0.6 | 0.7 | -0.7 | -0.7 | 0.5 | -0.5 | -0.5 | 0.5 | 0.7 | -0.8 | -0.8 |
reaction_time_peropinit_slope | 0.2 | 0.2 | 1.5 | 0.1 | 1.2 | -0.6 | 0.4 | 0.3 | 0.3 | 0.4 | -0.4 | 0.4 | 0.4 | -0.0 | 0.0 | 0.1 | -0.1 | -0.3 | 0.5 | 0.4 |
reaction_time_meanrt_slope | 0.0 | 0.0 | 0.2 | -0.2 | -0.5 | 0.3 | -0.1 | -0.2 | 0.0 | 0.2 | 0.2 | -0.1 | -0.1 | 0.2 | -0.2 | -0.2 | 0.2 | 0.2 | -0.2 | -0.2 |
reaction_time_devmedrt_slope | 1.7 | 1.8 | 2.3 | -1.2 | -1.3 | 1.5 | -1.3 | -1.4 | -1.3 | -1.3 | 1.4 | -1.3 | -1.4 | 1.2 | -1.2 | -1.2 | 1.2 | 1.3 | -1.5 | -1.4 |
pavca_ny_levercs_d4d5 | 2.8 | 3.9 | 6.4 | 2.0 | 2.5 | -2.3 | 1.8 | 2.0 | 2.0 | 1.9 | -1.9 | 1.9 | 1.9 | -1.7 | 1.7 | 1.7 | -1.7 | -1.9 | 2.1 | 2.0 |
pavca_ny_d2_magazine_cs | 0.5 | 0.6 | 1.1 | 0.6 | -0.9 | -0.1 | 0.8 | 0.6 | 0.7 | 0.8 | -0.8 | 0.7 | 0.7 | -1.0 | 1.0 | 1.0 | -1.0 | -0.7 | 0.6 | 0.6 |
ccp_trial_3_saline_dist_mm | 0.5 | 0.7 | 1.8 | 1.0 | 1.3 | -1.1 | 0.5 | 0.9 | 0.7 | 0.2 | -0.6 | 0.6 | 0.6 | -0.8 | 0.8 | 0.7 | -0.8 | -0.9 | 0.8 | 0.8 |
pavca_ny_d5_magazine_ncs | 0.1 | 0.1 | 0.3 | 0.5 | -0.1 | -0.1 | 0.3 | 0.3 | 0.1 | 0.2 | -0.2 | 0.3 | 0.3 | -0.4 | 0.4 | 0.4 | -0.3 | -0.3 | 0.2 | 0.2 |
ccp_change_in_locomotor_activity | 1.0 | 1.2 | 2.2 | 1.3 | -0.3 | -0.6 | 1.0 | 1.1 | 1.1 | 0.9 | -1.0 | 1.1 | 1.0 | -1.5 | 1.5 | 1.4 | -1.4 | -1.2 | 0.9 | 1.0 |
Conditioned locomotion | 0.0 | 0.0 | 0.1 | 0.1 | -0.2 | 0.3 | -0.1 | -0.1 | -0.1 | -0.3 | 0.1 | -0.1 | -0.1 | 0.0 | -0.0 | -0.0 | 0.0 | 0.2 | -0.2 | -0.2 |
Total sessions with >9 infusions | 0.0 | 0.0 | 0.0 | 0.2 | -0.0 | -0.2 | 0.1 | 0.2 | 0.2 | -0.0 | -0.2 | 0.2 | 0.2 | -0.1 | 0.1 | 0.1 | -0.1 | -0.1 | 0.2 | 0.2 |
Velocity during novelty place preference test | 0.1 | 0.1 | 0.9 | -0.1 | -1.0 | 0.5 | 0.1 | -0.0 | -0.1 | -0.3 | -0.2 | 0.2 | 0.1 | -0.4 | 0.4 | 0.4 | -0.3 | -0.1 | -0.0 | -0.0 |
crf_mi_active_responses | 0.8 | 0.9 | 1.9 | -0.9 | -0.3 | 0.9 | -1.1 | -0.9 | -1.1 | -1.4 | 1.0 | -1.0 | -1.0 | 0.8 | -0.8 | -0.9 | 0.9 | 0.9 | -1.0 | -1.0 |
pavca_mi_d1_avg_mag_lat | 7.1 | 8.5 | 9.6 | 2.9 | 2.6 | -3.1 | 2.9 | 3.0 | 3.0 | 3.0 | -3.0 | 2.9 | 2.9 | -2.7 | 2.8 | 2.8 | -2.8 | -2.9 | 3.1 | 3.0 |
pavca_mi_d3_magazine_ncs | 0.4 | 0.4 | 0.7 | 0.8 | -0.3 | -0.3 | 0.6 | 0.6 | 0.6 | 0.4 | -0.6 | 0.6 | 0.6 | -0.9 | 0.8 | 0.8 | -0.8 | -0.7 | 0.5 | 0.5 |
pavca_mi_d1_prob_lev | 3.5 | 4.8 | 7.2 | 2.2 | -0.1 | -1.5 | 2.2 | 2.1 | 2.3 | 2.1 | -2.2 | 2.1 | 2.2 | -2.7 | 2.6 | 2.6 | -2.6 | -2.3 | 2.0 | 2.1 |
pavca_mi_d1_avg_lev_lat | 3.1 | 4.6 | 7.3 | -2.3 | 0.2 | 1.4 | -2.1 | -2.1 | -2.2 | -1.9 | 2.1 | -2.0 | -2.1 | 2.7 | -2.7 | -2.7 | 2.6 | 2.2 | -1.9 | -2.0 |
pavca_mi_d3_prob_mag | 1.0 | 1.3 | 1.8 | -1.3 | -0.3 | 0.9 | -1.1 | -1.1 | -1.0 | -0.8 | 1.1 | -1.1 | -1.1 | 1.3 | -1.3 | -1.3 | 1.3 | 1.2 | -1.1 | -1.1 |
Total cortical area | 1.1 | 2.0 | 3.4 | -1.5 | -1.8 | 1.6 | -1.4 | -1.5 | -1.4 | -1.4 | 1.3 | -1.4 | -1.3 | 1.3 | -1.3 | -1.3 | 1.3 | 1.4 | -1.4 | -1.4 |
tb_th_sd | 0.3 | 0.3 | 0.7 | 0.8 | 0.0 | -0.5 | 0.5 | 0.6 | 0.4 | 0.1 | -0.5 | 0.5 | 0.5 | -0.7 | 0.7 | 0.7 | -0.7 | -0.6 | 0.5 | 0.5 |
Cortical porosity | 0.0 | 0.0 | 0.2 | -0.0 | -0.4 | 0.2 | -0.1 | -0.1 | -0.1 | -0.0 | 0.1 | -0.1 | -0.1 | 0.1 | -0.1 | -0.1 | 0.1 | 0.1 | -0.1 | -0.1 |
length | 0.7 | 1.4 | 4.5 | -1.4 | -2.1 | 1.7 | -1.0 | -1.2 | -1.1 | -1.0 | 1.0 | -1.0 | -1.1 | 0.8 | -0.9 | -0.8 | 0.9 | 1.1 | -1.3 | -1.2 |
Trabecular tissue density | 0.3 | 0.4 | 2.4 | 0.2 | 1.5 | -0.8 | 0.6 | 0.5 | 0.5 | 0.6 | -0.7 | 0.6 | 0.6 | -0.3 | 0.3 | 0.3 | -0.4 | -0.5 | 0.7 | 0.6 |
ctth_sd | 0.4 | 0.5 | 0.9 | -0.4 | -0.1 | 0.6 | -0.8 | -0.6 | -0.7 | -1.0 | 0.8 | -0.8 | -0.7 | 0.6 | -0.6 | -0.6 | 0.6 | 0.7 | -0.8 | -0.7 |
tautz: manual_spc7 | 0.4 | 0.6 | 0.8 | -0.7 | -0.2 | 0.6 | -0.8 | -0.8 | -0.7 | -0.6 | 0.8 | -0.7 | -0.8 | 0.9 | -0.9 | -0.9 | 0.9 | 0.8 | -0.7 | -0.8 |
tautz: manual_mpc15 | 0.0 | 0.1 | 0.2 | 0.1 | -0.3 | 0.0 | 0.1 | 0.2 | 0.2 | -0.0 | -0.2 | 0.2 | 0.2 | -0.4 | 0.4 | 0.4 | -0.4 | -0.2 | 0.1 | 0.1 |
tautz: manual_mpc18 | 0.6 | 0.9 | 5.8 | -1.0 | -2.4 | 1.4 | -0.6 | -0.9 | -0.6 | -0.3 | 0.6 | -0.6 | -0.6 | 0.5 | -0.6 | -0.5 | 0.6 | 0.8 | -0.9 | -0.8 |
tautz: manual_spc15 | 0.1 | 0.1 | 0.8 | 0.1 | -0.9 | 0.0 | 0.2 | 0.2 | 0.3 | 0.1 | -0.3 | 0.3 | 0.3 | -0.5 | 0.5 | 0.5 | -0.5 | -0.3 | 0.2 | 0.2 |
tautz: manual_spc21 | 0.8 | 1.1 | 1.5 | 1.2 | 1.1 | -1.0 | 1.0 | 1.0 | 1.0 | 0.9 | -1.0 | 1.0 | 0.9 | -1.0 | 1.0 | 1.0 | -1.0 | -1.0 | 1.0 | 1.0 |
tautz: manual_spc9 | 4.2 | 6.2 | 7.7 | -2.8 | -1.6 | 2.4 | -2.5 | -2.6 | -2.5 | -2.4 | 2.5 | -2.5 | -2.5 | 2.6 | -2.6 | -2.6 | 2.6 | 2.6 | -2.5 | -2.5 |
tautz: manual_mpc3 | 0.8 | 1.2 | 2.1 | -1.5 | -1.4 | 1.3 | -1.0 | -1.2 | -1.0 | -0.9 | 1.0 | -1.0 | -1.0 | 1.1 | -1.1 | -1.1 | 1.1 | 1.1 | -1.1 | -1.1 |
tautz: manual_spc12 | 1.1 | 1.5 | 2.7 | -0.8 | -0.7 | 1.0 | -1.4 | -1.2 | -1.4 | -1.6 | 1.4 | -1.4 | -1.3 | 1.2 | -1.2 | -1.2 | 1.2 | 1.2 | -1.3 | -1.3 |
tautz: manual_spc14 | 3.6 | 5.4 | 6.2 | 2.2 | 1.8 | -2.4 | 2.3 | 2.4 | 2.4 | 2.2 | -2.4 | 2.4 | 2.4 | -2.3 | 2.3 | 2.3 | -2.3 | -2.4 | 2.5 | 2.4 |
tautz: manual_spc8 | 0.1 | 0.2 | 1.8 | 0.1 | 1.3 | -0.5 | -0.2 | 0.1 | -0.2 | -0.4 | 0.2 | -0.2 | -0.2 | 0.3 | -0.3 | -0.3 | 0.2 | 0.1 | 0.0 | -0.0 |
tautz: manual_mpc7 | 0.9 | 1.0 | 4.2 | -0.8 | -2.0 | 1.4 | -1.0 | -1.0 | -0.9 | -0.9 | 0.9 | -0.9 | -0.9 | 0.5 | -0.6 | -0.6 | 0.7 | 0.8 | -1.1 | -1.0 |
tautz: manual_mpc16 | 0.0 | 0.0 | 0.1 | 0.2 | -0.3 | -0.0 | 0.1 | 0.2 | 0.2 | 0.2 | -0.2 | 0.2 | 0.2 | -0.3 | 0.3 | 0.3 | -0.3 | -0.2 | 0.2 | 0.2 |
tautz: manual_mpc4 | 0.3 | 0.4 | 0.6 | -0.4 | 0.3 | 0.3 | -0.6 | -0.5 | -0.7 | -0.6 | 0.7 | -0.7 | -0.6 | 0.8 | -0.7 | -0.7 | 0.7 | 0.6 | -0.6 | -0.6 |
tautz: manual_mpc10 | 0.9 | 1.3 | 2.6 | -0.5 | -0.2 | 0.8 | -1.3 | -1.0 | -1.3 | -1.6 | 1.3 | -1.3 | -1.4 | 1.0 | -1.0 | -1.0 | 1.0 | 1.1 | -1.2 | -1.2 |
tautz: manual_mpc5 | 1.7 | 2.1 | 3.3 | 1.8 | 1.1 | -1.4 | 1.3 | 1.5 | 1.4 | 1.1 | -1.4 | 1.4 | 1.4 | -1.6 | 1.6 | 1.6 | -1.6 | -1.5 | 1.4 | 1.4 |
tautz: manual_spc22 | 0.1 | 0.1 | 0.3 | -0.4 | 0.4 | 0.1 | -0.3 | -0.2 | -0.3 | -0.6 | 0.3 | -0.3 | -0.3 | 0.2 | -0.2 | -0.2 | 0.2 | 0.2 | -0.3 | -0.2 |
tautz: manual_mpc14 | 0.4 | 0.7 | 1.1 | -0.9 | -0.0 | 0.6 | -0.8 | -0.8 | -0.9 | -0.8 | 0.9 | -0.9 | -0.8 | 1.0 | -1.0 | -1.0 | 1.0 | 0.9 | -0.8 | -0.8 |
tautz: manual_mpc12 | 0.6 | 0.9 | 1.5 | -1.2 | -0.5 | 1.0 | -0.8 | -1.0 | -0.9 | -0.5 | 0.9 | -0.9 | -0.9 | 1.1 | -1.1 | -1.1 | 1.1 | 1.0 | -0.9 | -0.9 |
tautz: manual_mcs | 1.9 | 2.3 | 2.9 | 1.7 | 0.8 | -1.4 | 1.5 | 1.6 | 1.5 | 1.4 | -1.5 | 1.5 | 1.5 | -1.6 | 1.6 | 1.6 | -1.6 | -1.6 | 1.5 | 1.5 |
tautz: manual_spc17 | 0.1 | 0.1 | 1.1 | 0.2 | 1.0 | -0.4 | -0.0 | 0.1 | -0.0 | -0.1 | 0.0 | -0.0 | -0.0 | 0.1 | -0.1 | -0.1 | 0.1 | -0.0 | 0.1 | 0.1 |
tautz: manual_spc24 | 0.7 | 0.9 | 1.6 | 1.0 | -1.3 | -0.3 | 0.9 | 0.8 | 0.9 | 0.9 | -0.9 | 0.9 | 0.9 | -1.2 | 1.2 | 1.2 | -1.1 | -0.9 | 0.7 | 0.8 |
tautz: manual_spc4 | 0.9 | 1.3 | 1.9 | -1.1 | 0.2 | 0.7 | -1.2 | -1.1 | -1.2 | -1.1 | 1.2 | -1.2 | -1.3 | 1.4 | -1.4 | -1.4 | 1.3 | 1.2 | -1.0 | -1.1 |
tautz: manual_mpc9 | 0.2 | 0.3 | 0.4 | 0.7 | 0.2 | -0.5 | 0.4 | 0.5 | 0.4 | 0.1 | -0.5 | 0.4 | 0.5 | -0.6 | 0.6 | 0.6 | -0.6 | -0.6 | 0.4 | 0.5 |
tautz: manual_spc2 | 2.9 | 3.8 | 6.4 | 2.5 | 1.9 | -2.0 | 1.8 | 2.0 | 1.8 | 1.6 | -1.8 | 1.8 | 1.8 | -2.0 | 2.0 | 2.0 | -2.0 | -2.0 | 1.9 | 1.9 |
tautz: manual_spc13 | 1.5 | 2.3 | 4.2 | -2.0 | -1.3 | 1.5 | -1.3 | -1.6 | -1.3 | -0.7 | 1.3 | -1.3 | -1.3 | 1.8 | -1.8 | -1.7 | 1.7 | 1.6 | -1.3 | -1.4 |
tautz: manual_mpc19 | 0.6 | 0.7 | 1.1 | -0.3 | -0.4 | 0.6 | -0.9 | -0.8 | -0.9 | -1.1 | 0.9 | -0.9 | -0.9 | 0.9 | -0.9 | -0.9 | 0.9 | 0.8 | -0.9 | -0.8 |
tautz: manual_spc10 | 0.1 | 0.2 | 0.4 | -0.1 | -0.2 | 0.4 | -0.5 | -0.4 | -0.5 | -0.7 | 0.5 | -0.5 | -0.5 | 0.3 | -0.3 | -0.3 | 0.4 | 0.4 | -0.5 | -0.5 |
tautz: manual_spc11 | 0.4 | 0.5 | 1.1 | -0.6 | -0.6 | 0.7 | -0.8 | -0.7 | -0.8 | -1.0 | 0.8 | -0.8 | -0.8 | 0.6 | -0.6 | -0.6 | 0.6 | 0.7 | -0.8 | -0.8 |
tautz: manual_spc23 | 0.1 | 0.2 | 0.9 | -0.5 | -0.9 | 0.7 | -0.4 | -0.5 | -0.3 | -0.4 | 0.4 | -0.3 | -0.4 | 0.2 | -0.2 | -0.2 | 0.2 | 0.4 | -0.5 | -0.5 |
tautz: manual_spc6 | 0.0 | 0.0 | 0.1 | -0.3 | 0.1 | 0.0 | -0.0 | -0.1 | -0.0 | 0.1 | 0.0 | -0.0 | -0.0 | 0.2 | -0.2 | -0.2 | 0.1 | 0.1 | -0.0 | -0.0 |
tautz: manual_spc20 | 0.1 | 0.1 | 0.7 | 0.6 | 0.8 | -0.4 | -0.2 | 0.1 | -0.1 | -0.5 | 0.1 | -0.1 | -0.1 | -0.0 | 0.0 | -0.0 | -0.0 | -0.1 | 0.0 | 0.0 |
tautz: manual_mpc17 | 1.5 | 2.1 | 2.6 | 1.5 | 0.5 | -1.2 | 1.5 | 1.4 | 1.5 | 1.6 | -1.5 | 1.5 | 1.5 | -1.5 | 1.5 | 1.5 | -1.5 | -1.4 | 1.4 | 1.4 |
tautz: manual_mpc2 | 0.4 | 0.5 | 0.7 | 0.9 | 0.7 | -0.8 | 0.6 | 0.7 | 0.7 | 0.6 | -0.7 | 0.7 | 0.7 | -0.7 | 0.7 | 0.7 | -0.7 | -0.7 | 0.8 | 0.7 |
tautz: manual_spc1 | 0.9 | 1.0 | 1.4 | 0.9 | 0.4 | -0.9 | 1.1 | 1.0 | 1.1 | 1.2 | -1.1 | 1.1 | 1.1 | -1.0 | 1.0 | 1.0 | -1.0 | -1.0 | 1.1 | 1.0 |
tautz: manual_spc16 | 0.0 | 0.1 | 0.1 | 0.1 | 0.0 | -0.1 | 0.3 | 0.2 | 0.3 | 0.3 | -0.3 | 0.3 | 0.3 | -0.2 | 0.2 | 0.2 | -0.2 | -0.2 | 0.2 | 0.2 |
tautz: manual_mpc13 | 2.8 | 3.6 | 4.7 | -1.7 | -0.9 | 1.7 | -1.9 | -2.0 | -1.9 | -1.7 | 1.9 | -1.9 | -1.9 | 2.2 | -2.2 | -2.1 | 2.1 | 2.0 | -1.9 | -1.9 |
tautz: manual_spc5 | 1.1 | 1.5 | 3.1 | 1.8 | -0.2 | -0.7 | 1.2 | 1.2 | 1.1 | 0.9 | -1.1 | 1.1 | 1.1 | -1.6 | 1.6 | 1.6 | -1.5 | -1.3 | 0.9 | 1.0 |
tautz: manual_spc3 | 0.1 | 0.1 | 0.2 | 0.3 | 0.4 | -0.3 | 0.3 | 0.3 | 0.3 | 0.4 | -0.3 | 0.3 | 0.3 | -0.2 | 0.2 | 0.2 | -0.2 | -0.3 | 0.3 | 0.3 |
tautz: manual_mpc6 | 0.2 | 0.2 | 0.6 | -0.8 | -0.1 | 0.3 | -0.3 | -0.5 | -0.4 | -0.1 | 0.4 | -0.4 | -0.4 | 0.7 | -0.7 | -0.6 | 0.6 | 0.5 | -0.3 | -0.4 |
tautz: manual_spc18 | 1.0 | 1.3 | 1.9 | 1.3 | -0.4 | -0.7 | 1.1 | 1.1 | 1.1 | 1.0 | -1.1 | 1.1 | 1.1 | -1.4 | 1.4 | 1.4 | -1.3 | -1.2 | 1.0 | 1.0 |
tautz: manual_mpc11 | 0.0 | 0.1 | 0.2 | 0.1 | 0.1 | -0.3 | 0.3 | 0.2 | 0.3 | 0.5 | -0.3 | 0.3 | 0.3 | -0.0 | 0.0 | 0.1 | -0.1 | -0.2 | 0.3 | 0.3 |
tautz: manual_spc19 | 0.0 | 0.1 | 0.4 | 0.2 | 0.6 | -0.3 | -0.2 | 0.1 | -0.1 | -0.5 | 0.1 | -0.1 | -0.1 | -0.1 | 0.1 | 0.0 | -0.0 | -0.1 | -0.0 | 0.0 |
tautz: manual_mpc8 | 0.0 | 0.0 | 0.3 | -0.3 | -0.6 | 0.1 | 0.1 | -0.0 | 0.1 | 0.3 | -0.1 | 0.1 | 0.1 | -0.1 | 0.0 | 0.1 | -0.1 | -0.0 | 0.1 | 0.0 |
tautz: manual_mpc1 | 1.0 | 1.3 | 2.3 | -1.5 | -0.7 | 1.0 | -1.2 | -1.2 | -1.1 | -1.1 | 1.1 | -1.1 | -1.1 | 1.2 | -1.2 | -1.2 | 1.2 | 1.2 | -1.1 | -1.1 |
Sum of all infusions from LGA sessions | 0.1 | 0.2 | 0.9 | -0.1 | -0.9 | 0.2 | -0.3 | -0.3 | -0.3 | -0.3 | 0.5 | -0.4 | -0.5 | 0.3 | -0.3 | -0.3 | 0.3 | 0.3 | -0.5 | -0.3 |
Ambulatory time at time1 of open field | 0.4 | 0.4 | 0.5 | -0.6 | -0.0 | 0.6 | -0.7 | -0.7 | -0.7 | -0.6 | 0.7 | -0.7 | -0.7 | 0.7 | -0.7 | -0.7 | 0.7 | 0.7 | -0.7 | -0.7 |
dd_expon_k | 3.0 | 3.2 | 4.5 | 1.8 | 2.0 | -2.1 | 1.7 | 1.9 | 1.7 | 1.5 | -1.8 | 1.8 | 1.8 | -1.7 | 1.7 | 1.7 | -1.7 | -1.8 | 1.9 | 1.9 |
Delay discounting AUC-traditional | 3.0 | 3.2 | 4.6 | -1.8 | -2.1 | 2.1 | -1.6 | -1.9 | -1.7 | -1.5 | 1.8 | -1.7 | -1.8 | 1.6 | -1.7 | -1.6 | 1.7 | 1.8 | -1.9 | -1.8 |
The total number of resting periods in time1 | 0.2 | 0.3 | 0.7 | -0.6 | 0.8 | 0.1 | -0.5 | -0.4 | -0.1 | -0.2 | 0.5 | -0.5 | -0.5 | 0.7 | -0.7 | -0.7 | 0.7 | 0.5 | -0.3 | -0.4 |
Area under the delay curve | 3.0 | 3.2 | 4.6 | -1.8 | -2.1 | 2.1 | -1.6 | -1.9 | -1.7 | -1.5 | 1.8 | -1.7 | -1.8 | 1.6 | -1.7 | -1.6 | 1.7 | 1.8 | -1.9 | -1.8 |
punishment | 1.5 | 1.8 | 3.5 | -1.3 | -1.9 | 1.8 | -1.0 | -1.4 | -1.7 | -1.4 | 1.2 | -1.2 | -1.2 | 1.0 | -1.1 | -1.0 | 1.1 | 1.3 | -1.4 | -1.3 |
runstartmale1 | 0.5 | 0.5 | 1.4 | 1.2 | 0.6 | -0.7 | 0.6 | 0.7 | 0.6 | 0.5 | -0.7 | 0.7 | 0.7 | -0.8 | 0.8 | 0.8 | -0.8 | -0.7 | 0.7 | 0.6 |
locomotor2 | 3.2 | 3.8 | 4.5 | 1.8 | 1.8 | -1.9 | 2.0 | 2.0 | 1.9 | 1.9 | -2.0 | 2.1 | 2.0 | -1.9 | 1.9 | 1.9 | -1.9 | -2.0 | 2.1 | 2.0 |
Weight adjusted by age | 0.3 | 0.4 | 1.2 | -0.7 | -1.1 | 0.6 | -0.5 | -0.6 | -0.6 | -0.5 | 0.5 | -0.5 | -0.5 | 0.6 | -0.6 | -0.6 | 0.6 | 0.6 | -0.6 | -0.5 |
Liver selenium concentration | 1.7 | 2.1 | 3.7 | -1.2 | -1.9 | 1.6 | -1.5 | -1.5 | -1.5 | -1.5 | 1.4 | -1.4 | -1.4 | 1.2 | -1.2 | -1.3 | 1.3 | 1.4 | -1.5 | -1.5 |
Liver rubidium concentration | 2.6 | 3.3 | 4.0 | -2.0 | -1.7 | 1.9 | -1.8 | -1.9 | -1.7 | -1.6 | 1.8 | -1.9 | -1.8 | 1.8 | -1.8 | -1.8 | 1.8 | 1.9 | -1.9 | -1.9 |
Liver iron concentration | 0.1 | 0.2 | 0.3 | 0.4 | 0.6 | -0.5 | 0.4 | 0.4 | 0.1 | 0.0 | -0.4 | 0.4 | 0.5 | -0.3 | 0.4 | 0.4 | -0.4 | -0.4 | 0.4 | 0.5 |
Liver cobalt concentration | 0.1 | 0.2 | 0.4 | -0.0 | 0.4 | 0.2 | -0.6 | -0.3 | -0.1 | -0.5 | 0.6 | -0.5 | -0.6 | 0.2 | -0.2 | -0.3 | 0.3 | 0.3 | -0.5 | -0.4 |
Liver cadmium concentration | 0.2 | 0.2 | 0.4 | 0.5 | 0.1 | -0.4 | 0.5 | 0.5 | 0.5 | 0.6 | -0.4 | 0.5 | 0.4 | -0.6 | 0.6 | 0.6 | -0.6 | -0.5 | 0.4 | 0.5 |
Liver zinc concentration | 0.3 | 0.3 | 1.2 | -0.8 | -1.1 | 0.8 | -0.5 | -0.6 | -0.5 | -0.5 | 0.4 | -0.4 | -0.5 | 0.3 | -0.3 | -0.3 | 0.3 | 0.5 | -0.5 | -0.5 |
Liver sodium concentration | 3.8 | 4.1 | 4.9 | -2.2 | -1.2 | 2.0 | -2.0 | -2.1 | -2.1 | -1.9 | 2.0 | -1.9 | -2.0 | 2.2 | -2.2 | -2.2 | 2.2 | 2.1 | -1.9 | -2.0 |
Liver manganese concentration | 0.1 | 0.2 | 1.6 | -0.0 | -1.3 | 0.6 | -0.3 | -0.3 | -0.2 | -0.3 | 0.2 | -0.2 | -0.2 | -0.1 | 0.1 | 0.1 | -0.0 | 0.2 | -0.3 | -0.3 |
For each tested trait, stats based on TWAS chi2 (squared Z-score) for the above models are shown. Avg chi2 ratio is the mean chi2 across all models for this gene, divided by the mean chi2 across all models for all genes. Avg chi2 is the mean chi2 across all models for this gene. Max chi2 is the highest chi2 across all models for this gene.
The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.