Hub : Genes

Samm50

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000011952 0.37 0.13 2.8e-16 0.21 0.21 0.21 0.22 1.2e-11 2.9e-11 1.3e-11 3.2e-12
2 Brain gene expression ENSRNOG00000011952 0.31 0.13 0.0e+00 0.17 0.24 0.24 0.25 2.5e-15 9.2e-22 2.1e-22 3.7e-23
3 Brain mRNA stability ENSRNOG00000011952 0.2 0.11 7.8e-10 0.1 0.1 0.1 0.1 1.2e-09 9.0e-10 1.1e-09 1.0e-09
4 IL gene expression ENSRNOG00000011952 0.34 0.15 1.4e-04 0.13 0.12 0.1 0.14 4.4e-04 7.0e-04 2.0e-03 3.8e-04
5 Liver gene expression ENSRNOG00000011952 0.06 0.04 5.8e-05 0.01 0.01 0.01 0.01 9.5e-03 4.3e-02 1.2e-02 2.8e-02
6 NAcc gene expression ENSRNOG00000011952 0.12 0.08 4.1e-05 0.03 0.05 0.05 0.04 4.2e-03 1.1e-04 1.7e-04 2.6e-04
7 PL gene expression ENSRNOG00000011952 0.24 0.1 1.5e-13 0.1 0.07 0.14 0.1 7.6e-08 2.4e-06 3.8e-11 4.0e-08
8 PL mRNA stability ENSRNOG00000011952 0.1 0.06 1.7e-04 0.06 0.05 0.06 0.05 2.7e-05 1.7e-04 4.0e-05 6.7e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.92.94.8-1.5-2.21.4-1.2-1.1-2.1-2.01.9
BMI without tail2.14.46.5-2.4-2.2-1.0-2.2-2.5-2.4-2.6-0.3
Body weight0.62.74.3-1.9-2.10.4-1.6-1.6-2.0-1.90.9
Epididymis fat weight0.20.50.9-0.8-1.00.2-0.6-0.7-0.9-0.80.3
Glucose1.72.74.31.82.00.21.81.62.12.0-0.2
Heart weight0.10.20.7-0.1-0.00.80.30.40.40.10.7
Left kidney weight8.223.539.9-4.8-6.32.5-4.3-3.7-6.1-5.74.1
Right kidney weight8.123.139.7-4.7-6.33.2-3.9-3.3-5.8-5.64.7
Tail length0.10.31.0-0.5-0.1-1.0-0.3-0.7-0.2-0.2-0.9
Length with tail0.00.10.2-0.4-0.3-0.2-0.3-0.4-0.3-0.20.0
Length without tail0.51.03.20.7-0.11.80.60.90.00.41.8
Liver weight, left0.20.30.90.1-0.31.00.20.4-0.3-0.10.9
Liver weight, right0.10.20.3-0.6-0.4-0.4-0.5-0.4-0.3-0.4-0.5
Parametrial fat weight0.00.10.20.2-0.00.30.10.2-0.20.00.4
Retroperitoneal fat weight0.62.14.3-1.3-1.90.6-1.4-1.2-2.1-1.61.1
Intraocular pressure0.00.10.2-0.5-0.1-0.3-0.2-0.20.1-0.1-0.4
Extensor digitorum longus weight0.41.72.4-1.4-1.3-0.9-1.6-1.5-1.5-1.4-0.6
Soleus weight0.30.72.20.60.11.50.70.80.10.31.5
Tibialis anterior weight0.00.00.10.1-0.1-0.2-0.1-0.1-0.4-0.1-0.2
Tibia length0.10.30.7-0.5-0.60.7-0.3-0.2-0.3-0.50.9
Number of licking bursts0.40.51.40.10.7-1.10.1-0.00.80.5-1.2
Food consumed during 24 hour testing period1.01.24.5-0.3-1.01.8-0.10.1-0.7-0.52.1
Times rat made contact with spout0.60.62.4-0.2-0.61.40.20.3-0.2-0.31.5
Mean time between licks in bursts1.31.83.20.91.7-1.11.00.71.81.5-1.7
Mean num. licks in bursts1.51.85.9-0.3-1.22.2-0.00.2-1.1-0.82.4
Std. dev. time between licks in bursts0.40.40.70.80.8-0.10.80.70.60.8-0.2
Water consumed over 24 hours1.21.43.3-1.0-1.51.3-0.6-0.4-1.0-1.11.8
Indifference point 0 sec0.00.10.10.20.2-0.00.20.30.40.2-0.0
Indifference point AUC0.50.61.01.00.70.80.90.90.60.80.5
Indifference point function ln k1.82.64.1-2.0-1.8-0.8-1.9-1.8-1.6-1.8-0.3
Indifference point function log k1.82.64.1-2.0-1.8-0.8-1.9-1.8-1.6-1.8-0.3
Delay discounting total patch changes 0 sec0.10.10.30.20.4-0.20.20.30.50.3-0.3
Delay discounting total patch changes 12 sec0.50.71.30.80.51.20.81.00.50.50.9
Delay discounting total patch changes 18 sec0.60.81.21.00.90.50.91.01.11.00.2
Delay discounting total patch changes 24 sec0.40.50.8-0.7-0.6-0.7-0.8-0.9-0.6-0.7-0.6
Delay discounting total patch changes 6 sec0.71.11.61.10.90.91.21.31.21.10.6
Delay discounting time to switch 0 sec0.30.40.6-0.5-0.5-0.8-0.8-0.7-0.8-0.7-0.6
Delay discounting water rate 0 sec0.10.10.3-0.5-0.40.4-0.2-0.1-0.2-0.30.4
Delay discounting water rate 12 sec2.13.24.9-2.1-1.6-1.5-2.1-2.2-1.5-1.7-1.3
Delay discounting water rate 18 sec0.00.00.0-0.00.1-0.00.1-0.10.20.2-0.2
Delay discounting water rate 24 sec1.31.82.9-1.5-1.7-0.0-1.3-1.4-1.6-1.60.5
Delay discounting water rate 6 sec0.10.10.6-0.10.2-0.6-0.1-0.20.20.1-0.8
Locomotor activity0.91.52.3-1.5-1.50.3-1.3-1.2-1.3-1.50.6
Locomotor testing distance0.00.00.0-0.10.1-0.1-0.2-0.10.10.0-0.1
Locomotor testing rearing0.30.40.7-0.8-0.6-0.3-0.8-0.8-0.5-0.8-0.2
Light reinforcement 12.24.05.8-2.3-2.2-1.0-2.4-2.2-2.2-2.3-0.3
Light reinforcement 23.24.25.8-2.3-2.2-1.3-2.4-2.3-2.3-2.3-0.8
Reaction time number correct0.60.82.30.61.1-1.00.40.20.70.8-1.5
Reaction time mean minus median0.10.20.30.20.40.30.50.40.50.40.3
Reaction time mean minus median AUC0.10.10.2-0.4-0.20.2-0.1-0.1-0.2-0.30.4
Reaction time num false alarms0.30.41.10.10.6-0.70.10.11.00.5-1.0
Reaction time num false alarms AUC0.10.20.60.10.4-0.30.20.10.80.4-0.6
Reaction time trials correct on left0.60.82.30.61.1-1.00.40.20.70.8-1.5
Reaction time trials on left0.60.92.30.71.1-1.00.50.30.80.9-1.5
Reaction time mean0.70.91.41.11.10.21.11.01.21.2-0.0
Reaction time mean AUC0.71.01.51.11.10.31.11.11.21.20.0
Median of all reaction times1.11.52.21.41.30.41.41.31.41.50.0
Reaction time omissions1.21.72.71.31.60.11.51.31.61.5-0.4
Reaction time false alarm rate0.00.00.1-0.2-0.10.1-0.0-0.00.40.00.0
Reaction time premature initiation rate0.91.24.00.9-0.01.80.71.0-0.30.32.0
Reaction time premature initiations0.60.81.41.10.51.20.91.10.10.71.1
Std. dev. reaction times0.10.20.30.40.50.20.50.40.50.50.2
Reaction time trials completed0.60.92.30.71.1-1.00.50.30.80.9-1.5
Reaction time trials AUC0.40.62.00.50.9-1.00.30.10.60.6-1.4
Social response proportion0.40.40.7-0.6-0.90.2-0.4-0.5-0.7-0.80.8
Social responses0.20.20.6-0.3-0.5-0.1-0.4-0.4-0.8-0.60.4
Social time2.63.55.02.22.20.32.22.02.12.2-0.1
Conditioned locomotion0.30.40.80.20.9-0.60.40.30.90.7-0.8
Cocaine response after cond. corrected0.40.41.0-0.7-0.2-1.0-0.6-0.7-0.1-0.4-1.0
Cocaine response after cond. not corrected0.91.02.1-1.1-0.3-1.5-0.9-1.1-0.2-0.6-1.4
Cocaine response before conditioning0.10.10.20.30.4-0.30.20.10.50.3-0.3
Saline control response0.40.50.9-0.9-0.4-1.0-0.8-0.8-0.2-0.5-0.8
Condit. Reinf. active minus inactive responses0.60.81.30.90.61.21.01.00.50.71.0
Condit. Reinf. active-inactive response ratio0.30.30.50.60.40.70.60.60.30.50.6
Condit. Reinf. active responses0.50.72.50.2-0.31.50.40.5-0.4-0.11.6
Condit. Reinf. inactive responses0.60.72.4-0.3-0.91.3-0.10.1-0.8-0.61.5
Condit. Reinf. lever presses0.20.20.7-0.0-0.40.5-0.10.1-0.7-0.50.8
Condit. Reinf. lever reinforcers received0.40.61.90.50.11.40.60.8-0.10.21.3
Pavlov. Cond. lever latency0.10.20.4-0.10.4-0.50.10.10.70.3-0.6
Pavlov. Cond. magazine entry latency0.70.81.91.41.00.41.11.10.50.90.4
Pavlov. Cond. change in total contacts0.60.92.50.8-0.11.50.70.8-0.30.11.6
Pavlov. Cond. index score0.30.30.80.90.40.60.70.7-0.00.40.6
Pavlov. Cond. latency score0.30.30.80.90.40.50.70.7-0.10.30.6
Pavlov. Cond. lever contacts0.20.20.70.3-0.30.70.10.2-0.6-0.30.8
Pavlov. Cond. magazine entry number0.30.40.9-0.9-0.4-0.6-0.7-0.70.0-0.3-0.7
Pavlov. Cond. intertrial magazine entries0.20.31.2-0.1-0.21.10.10.30.10.01.0
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.70.30.40.50.5-0.20.20.4
Pavlov. Cond. response bias0.30.40.90.90.20.90.70.7-0.10.20.9
Conditioned reinforcement - actives0.90.91.21.01.00.41.11.11.11.10.1
Conditioned reinforcement - inactives0.10.20.30.30.20.60.50.50.20.10.5
Conditioned locomotion1.72.13.1-1.7-1.7-0.3-1.6-1.6-1.6-1.70.3
Intermittent access intake day 1-15 change0.20.20.30.40.5-0.50.20.20.40.5-0.6
Intermittent access intake escalation0.20.20.80.10.3-0.8-0.1-0.10.20.2-0.9
Intermittent access intake escalation 20.30.30.60.60.70.00.50.60.80.8-0.2
Intermitt. access day 1 inactive lever presses0.91.02.1-0.7-1.11.1-0.3-0.4-1.1-1.11.5
Intermitt. access day 15 inactive lever presses1.51.65.90.5-0.42.20.80.9-0.3-0.02.4
Intermitt. access escalation Index0.10.10.1-0.1-0.2-0.2-0.3-0.3-0.3-0.2-0.2
Intermittent access day 1 total infusions0.20.20.6-0.3-0.60.6-0.0-0.0-0.2-0.40.8
Intermittent access day 15 total infusions0.10.10.3-0.5-0.5-0.1-0.3-0.4-0.3-0.40.0
Intermittent access terminal intake (last 3 days)0.10.10.2-0.2-0.50.2-0.2-0.1-0.3-0.30.3
Intermittent access total infusions0.20.20.5-0.6-0.7-0.0-0.4-0.4-0.4-0.50.1
Intermittent access day 1 locomotion0.30.30.4-0.6-0.5-0.5-0.6-0.6-0.3-0.5-0.4
Intermittent access day 15 total locomotion1.81.92.8-1.7-1.3-1.0-1.6-1.6-1.3-1.5-0.6
Intermittent access total locomotion1.31.52.1-1.5-1.4-0.5-1.5-1.3-1.3-1.5-0.1
Intermittent access standard deviation0.30.30.6-0.4-0.70.6-0.4-0.2-0.6-0.60.7
Cocaine induced anxiety2.02.34.0-1.5-2.01.0-1.2-1.1-1.8-1.71.5
Post-drug Anxiety0.91.01.8-0.8-1.21.0-0.5-0.5-1.1-1.11.3
Baseline Anxiety2.12.23.91.62.0-0.61.31.31.71.8-1.2
Lifetime Intake0.30.40.8-0.8-0.90.1-0.6-0.6-0.5-0.70.3
Incentive Sensitization - Responses1.51.55.4-0.0-1.02.00.00.3-1.0-0.62.3
Incentive Sensitization - Breakpoint1.71.76.0-0.1-1.12.1-0.00.3-1.1-0.72.5
Progressive ratio test 1 active lever presses0.20.20.30.40.40.00.50.50.60.5-0.1
Progressive ratio test 1 breakpoint0.40.40.60.60.70.00.70.70.80.7-0.1
Progressive ratio test 1 inactive lever presses0.10.10.30.0-0.10.40.20.2-0.1-0.10.6
Progressive ratio test 2 active lever presses0.60.72.20.5-0.21.40.50.8-0.10.21.5
Progressive ratio test 2 breakpoint0.70.82.50.6-0.21.60.60.9-0.00.21.6
Progressive ratio test 2 inactive lever presses0.70.82.60.6-0.11.50.80.9-0.00.21.6
Total sessions with >9 infusions0.50.50.9-0.9-0.6-0.8-0.8-0.8-0.3-0.7-0.7
Short access day 1 total inactive lever presses1.51.62.8-1.1-1.71.2-0.7-0.7-1.3-1.51.7
Short access day 10 total inactive lever presses2.32.54.0-1.6-2.01.0-1.3-1.2-1.9-1.91.6
Short access day 1 total infusions0.50.51.0-0.7-1.00.7-0.4-0.5-0.6-0.80.9
Short access day 10 total infusions0.10.20.50.10.3-0.50.30.10.50.3-0.7
Short access total infusions0.30.30.6-0.8-0.80.2-0.5-0.5-0.4-0.70.3
Short access day 1 locomotion0.20.20.3-0.5-0.5-0.2-0.4-0.5-0.3-0.5-0.1
Short access day 10 total locomotion0.30.41.10.20.7-0.90.20.00.60.3-1.1
Short access total locomotion0.20.20.4-0.4-0.1-0.7-0.3-0.40.0-0.3-0.7
Compulsive drug intake0.90.91.61.00.51.31.11.10.40.71.0
One hour access (0.3 mA shock)0.10.10.1-0.3-0.4-0.3-0.3-0.3-0.2-0.2-0.2
One hour access (shock baseline)1.01.22.7-1.1-0.5-1.6-1.1-1.2-0.4-0.7-1.4
Number of responses in last shaping day1.01.11.71.31.00.51.21.21.11.20.3
Context. condit. distance diff. score1.82.23.8-1.8-1.90.9-1.3-1.1-1.5-1.81.2
Locomotion velocity, session 11.21.32.3-0.9-1.50.9-0.9-0.7-1.5-1.21.3
Locomotion distance, session 10.10.20.20.50.30.50.50.50.30.50.4
Locomotion velocity, session 24.55.38.5-2.4-2.8-0.6-2.6-2.4-2.9-2.70.1
Locomotion distance, session 20.30.40.90.90.50.70.70.80.20.60.7
Locomotion velocity, session 32.63.14.4-2.0-2.1-0.5-2.0-1.9-2.1-2.10.0
Locomotion distance, session 30.80.92.2-0.7-0.3-1.5-0.9-1.0-0.5-0.6-1.4
Stereotopy head waving bouts, day 31.72.03.6-1.0-1.90.9-1.1-0.9-1.9-1.61.4
Stereotopy head waving duration, day 33.13.86.9-2.0-2.60.9-1.8-1.6-2.4-2.31.5
Locomotion velocity, session 70.60.71.0-0.9-0.8-0.6-0.9-0.9-1.0-1.0-0.3
Locomotion distance, session 70.00.10.10.30.3-0.30.20.10.00.2-0.3
Stereotopy head waving bouts, day 74.95.68.6-2.8-2.9-0.1-2.6-2.4-2.7-2.80.6
Stereotopy head waving duration, day 72.93.55.6-2.4-2.2-0.6-2.1-2.1-2.0-2.2-0.1
Locomotion velocity, session 85.36.411.1-2.4-3.31.4-2.2-1.8-3.2-3.02.2
Locomotion distance, session 81.21.83.0-1.4-1.70.4-1.3-1.1-1.7-1.70.8
Degree of sensitization distance1.01.03.40.5-0.21.80.70.9-0.10.11.9
Degree of sensitization stereotypy2.83.15.1-2.3-2.1-0.4-2.0-1.9-1.8-2.00.0
Condit. Reinf. active minus inactive responses1.82.03.31.61.8-0.11.51.41.61.6-0.5
Condit. Reinf. active-inactive response ratio1.31.42.71.11.50.21.31.21.61.3-0.3
Condit. Reinf. active responses1.51.83.21.51.8-0.81.21.01.41.5-1.2
Condit. Reinf. inactive responses0.30.30.80.70.6-0.80.20.10.20.5-0.9
Incentive salience index mean1.72.03.51.71.9-0.31.51.31.51.7-0.8
Condit. Reinf. lever presses0.50.61.11.01.1-0.60.70.60.60.8-0.8
Time in familiar zone, hab. session 10.70.71.2-0.8-1.10.2-0.8-0.7-1.0-1.00.5
Time in novel zone, hab. session 10.20.20.6-0.10.4-0.30.10.10.80.3-0.6
Total zone transitions, hab. session 11.11.52.51.51.6-0.21.21.11.41.5-0.6
Total locomotion distance, hab. session 10.50.71.0-0.6-0.7-0.8-1.0-1.0-1.0-0.8-0.6
Locomotion velocity, hab. session 10.50.71.3-0.6-0.8-0.8-1.0-1.0-1.2-0.9-0.5
Time in familiar zone, hab. session 20.30.40.6-0.5-0.3-0.8-0.7-0.7-0.5-0.5-0.7
Time in novel zone, hab. session 20.30.30.50.20.20.70.50.60.70.50.5
Total zone transitions, hab. session 20.40.51.80.3-0.41.10.10.3-0.6-0.31.3
Total locomotion distance, hab. session 20.30.51.1-0.5-0.8-0.0-0.7-0.6-1.1-0.80.3
Locomotion velocity, hab. session 20.20.30.9-0.2-0.60.0-0.5-0.4-0.9-0.60.3
Novel to familiar place preference ratio0.20.20.7-0.8-0.60.2-0.5-0.5-0.2-0.50.3
Novelty place preference0.50.51.3-1.1-0.90.1-0.8-0.7-0.5-0.70.3
Time in novel zone, NPP test0.60.71.7-1.3-1.00.1-0.9-0.8-0.5-0.80.3
Total zone transitions, NPP test0.20.30.60.80.50.60.70.70.30.50.5
Total locomotion distance, NPP test0.70.91.7-0.9-1.1-0.5-1.1-1.1-1.3-1.1-0.2
Locomotion velocity, NPP test0.40.61.1-0.5-0.6-0.8-0.8-0.9-1.0-0.8-0.5
Pavlov. Cond. lever latency0.81.01.7-1.2-1.30.6-0.9-0.7-1.0-1.21.0
Pavlov. Cond. magazine entry latency3.34.36.52.42.60.22.32.12.42.5-0.4
Pavlov. Cond. change in total contacts3.03.24.92.12.20.11.91.82.12.2-0.5
Pavlov. Cond. index score2.32.94.42.02.10.11.91.72.02.1-0.4
Pavlov. Cond. latency score1.41.82.81.61.7-0.01.41.31.51.6-0.5
Pavlov. Cond. lever contacts1.11.32.11.31.5-0.70.90.81.21.3-1.1
Pavlov. Cond. magazine entry number3.54.46.9-2.4-2.6-0.1-2.3-2.1-2.5-2.60.5
Pavlov. Cond. intertrial magazine entries0.00.00.10.30.2-0.10.10.10.20.2-0.1
Pavlov. Cond. lever-magazine prob. diff.2.63.25.22.12.3-0.11.91.82.12.2-0.7
Pavlov. Cond. response bias3.34.06.62.32.6-0.32.11.92.32.4-1.0
Bone: apparent density0.20.30.60.50.6-0.10.50.40.80.7-0.3
Bone surface0.00.10.20.30.20.20.30.20.40.40.1
Bone volume0.00.00.10.20.10.00.20.10.40.2-0.1
Bone: connectivity density0.10.10.20.30.3-0.30.20.10.50.4-0.3
Bone: cortical apparent density1.41.93.11.81.50.71.61.61.31.50.4
Bone: cortical area0.20.30.8-0.9-0.80.1-0.5-0.5-0.4-0.60.2
Bone: cortical porosity0.10.10.3-0.5-0.4-0.2-0.3-0.3-0.2-0.4-0.1
Bone: cortical porosity0.40.40.8-0.9-0.8-0.2-0.7-0.7-0.6-0.7-0.0
Bone: cortical thickness0.91.42.01.31.11.11.41.41.21.20.7
Bone: cortical thickness0.50.61.10.70.41.00.80.80.60.60.9
Bone: cortical tissue density1.21.62.71.71.30.81.51.51.11.30.5
Bone: elastic displacement1.61.82.7-1.6-1.6-0.3-1.5-1.4-1.5-1.60.0
Bone: elastic work4.25.49.1-2.7-3.00.2-2.4-2.3-2.7-2.80.9
Bone: endosteal estimation3.67.711.4-3.4-3.4-0.6-3.1-3.0-3.0-3.30.2
Bone: endosteal perimeter3.98.112.6-3.5-3.0-1.7-3.3-3.3-2.7-3.1-1.0
Bone: final force0.60.93.40.2-0.31.70.50.7-0.1-0.01.8
Bone: final moment0.71.24.70.1-0.62.00.50.6-0.3-0.22.2
Bone: marrow area3.67.611.5-3.4-3.4-0.5-3.1-2.9-3.0-3.30.3
Bone: maximum diameter3.46.210.0-3.1-3.20.0-2.6-2.5-2.7-2.90.7
Bone: maximum force0.71.23.9-0.6-1.11.7-0.20.0-0.7-0.72.0
Bone: maximum moment0.91.65.2-0.7-1.31.9-0.20.0-0.9-0.92.3
Bone: minimum diameter2.03.75.5-2.3-1.9-1.5-2.3-2.3-1.7-2.0-1.0
Bone: periosteal estimation2.34.77.5-2.7-2.7-0.3-2.4-2.3-2.3-2.50.3
Bone: periosteal perimeter2.94.88.5-2.9-2.3-1.3-2.5-2.6-1.9-2.4-0.9
Bone: post-yield work1.72.33.91.31.02.01.71.81.31.11.7
Bone: stiffness0.81.32.00.80.81.41.31.41.31.01.1
Bone: tissue strength0.20.20.80.0-0.20.80.20.4-0.0-0.00.9
Bone: trabecular number0.30.51.40.00.6-1.00.1-0.10.90.6-1.2
Bone: trabecular spacing0.91.12.4-0.7-1.30.8-0.8-0.5-1.5-1.31.1
Bone: trabecular thickness0.00.00.10.20.0-0.3-0.0-0.10.00.1-0.1
Bone: trabecular tissue density0.50.71.21.10.80.71.01.00.70.90.4
Breakpoint value in progressive ratio session0.30.30.6-0.6-0.6-0.1-0.6-0.6-0.8-0.80.0
Distance traveled before self-admin0.40.40.60.60.50.70.70.80.40.60.6
Distance traveled after self-admin0.40.50.9-0.5-0.90.6-0.3-0.5-0.9-0.80.9
Delta time in closed arm before/after self-admin1.11.02.11.00.51.51.01.20.60.71.3
Delta time in open arm before/after self-admin3.63.44.7-2.2-1.8-1.5-2.2-2.1-1.7-2.0-1.0
Diff in mean of infusions in LGA sessions4.75.38.22.72.12.02.62.92.12.31.3
Extinction: sum of active levers before priming0.20.20.50.50.50.50.70.60.10.30.4
Active lever presses in extinction session 60.30.20.90.2-0.00.90.10.5-0.10.00.9
Delta distance traveled before/after self-admin2.32.44.0-1.8-2.0-0.1-1.5-1.7-1.8-2.00.5
Delta ambulatory time before/after self-admin1.41.52.5-1.5-1.60.1-1.3-1.2-1.3-1.50.5
Time in closed arm before self-admin0.80.91.50.91.2-1.00.80.41.11.0-1.2
Time in closed arm after self-admin0.10.10.30.40.4-0.10.30.30.50.4-0.2
Time in open arm before self-admin0.10.10.10.20.4-0.20.10.10.30.3-0.3
Time in open arm after self-admin2.42.63.5-1.8-1.5-1.2-1.9-1.9-1.7-1.7-0.8
Sum of active levers in priming session hrs 5-60.20.20.5-0.5-0.50.1-0.5-0.4-0.7-0.60.3
Time to tail flick, vehicle, before self-admin0.10.10.3-0.1-0.20.4-0.1-0.0-0.2-0.20.5
Time to tail flick, vehicle, after self-admin0.30.30.8-0.4-0.0-0.9-0.5-0.5-0.1-0.2-0.8
Time to tail flick, test, before self-admin0.20.10.4-0.4-0.4-0.3-0.7-0.4-0.3-0.3-0.2
Time to tail flick, test, after self-admin0.80.81.31.11.1-0.40.70.81.11.1-0.8
Delta time to tail flick, vehicle, before/after SA0.10.10.40.2-0.20.60.10.3-0.10.10.6
Delta time to tail flick, test, before/after SA0.80.71.11.01.1-0.11.00.70.90.9-0.4
Ambulatory time before self-admin0.50.51.00.60.31.00.80.70.30.41.0
Ambulatory time after self-admin0.20.20.7-0.2-0.50.60.1-0.1-0.4-0.40.8
Total heroin consumption0.20.21.10.2-0.11.0-0.10.5-0.30.10.7
Area under the delay curve2.22.33.61.71.90.21.71.71.71.7-0.5
Delay disc. indifference point, 0s delay0.30.30.5-0.7-0.6-0.4-0.5-0.7-0.5-0.5-0.3
Delay disc. indifference point, 16s delay1.81.93.21.61.8-0.31.51.31.41.5-0.9
Delay disc. indifference point, 2s delay0.80.91.31.11.10.30.91.11.11.2-0.1
Delay disc. indifference point, 24s delay0.80.81.31.11.10.31.11.00.90.9-0.0
Delay disc. indifference point, 4s delay1.11.22.01.10.91.21.21.41.01.00.9
Delay disc. indifference point, 8s delay2.32.44.01.72.0-0.41.61.61.81.7-1.0
Delay discount exponential model param2.32.53.7-1.8-1.9-0.3-1.8-1.8-1.7-1.70.3
Delay discount hyperbolic model param1.71.92.7-1.6-1.6-0.3-1.5-1.6-1.5-1.50.2
Fecal boli incidents, locomotor time 10.10.10.20.0-0.20.2-0.2-0.1-0.4-0.20.5
Change in fecal boli incidents, locomotor task0.40.40.8-0.9-0.3-0.8-0.4-0.8-0.1-0.4-0.9
Time >=10cm from walls, locomotor time 10.30.30.6-0.5-0.70.0-0.8-0.4-0.7-0.50.4
Bouts of movement, locomotor time 10.20.20.30.50.40.40.60.50.30.40.5
Total resting periods, locomotor time 10.40.50.80.90.60.50.80.90.60.70.6
Rest time, locomotor task time 10.10.20.4-0.2-0.40.1-0.4-0.3-0.7-0.50.2
Distance moved, locomotor task time 10.00.00.1-0.0-0.10.2-0.00.10.00.10.3
Vertical activity count, locomotor time 10.10.10.30.30.40.40.30.50.50.50.2
Time >=10cm from walls, locomotor time 20.30.30.8-0.4-0.2-0.9-0.6-0.5-0.2-0.2-0.8
Bouts of movement, locomotor time 21.01.12.01.21.20.41.41.11.11.10.2
Total resting periods, locomotor time 21.51.62.81.51.40.61.71.41.31.30.3
Rest time, locomotor task time 20.10.20.30.50.6-0.20.40.30.40.3-0.5
Distance moved, locomotor task time 21.11.32.1-1.3-1.4-0.2-1.3-1.1-1.3-1.20.3
Vertical activity count, locomotor time 21.51.72.8-1.5-1.6-0.2-1.7-1.3-1.5-1.40.0
Weight adjusted by age1.01.11.7-1.2-1.1-0.5-1.2-1.2-1.2-1.3-0.1
Seeking ratio, delayed vs. immediate footshock0.91.03.10.51.2-1.30.40.21.00.7-1.8
Locomotion in novel chamber2.83.47.3-1.7-0.7-2.7-2.0-2.1-0.8-1.2-2.5
Locomotion in novel chamber post-restriction0.30.31.00.20.6-1.0-0.2-0.20.40.4-0.9
Progressive ratio1.21.42.11.31.20.71.31.41.31.30.0
Food seeking constrained by brief footshock0.40.50.8-0.6-0.90.5-0.6-0.5-0.9-0.80.7
Seeking ratio, punishment vs. effort0.81.01.6-1.0-1.20.1-1.0-1.0-1.3-1.10.7
Run reversals in cocaine runway, females1.31.24.5-0.30.3-2.1-0.8-0.90.10.1-1.9
Run reversals in cocaine runway, males0.50.40.9-0.9-0.8-0.2-0.8-0.8-0.5-0.7-0.0
Latency to leave start box in cocaine runway1.21.32.1-1.2-1.40.3-0.9-1.1-1.4-1.50.8
Latency to leave start box in cocaine runway, F0.30.30.6-0.4-0.70.5-0.1-0.3-0.6-0.60.8
Latency to leave start box in cocaine runway, M1.11.01.5-1.1-1.20.4-1.0-0.9-1.2-1.20.9
Cd content in liver0.50.61.50.40.80.50.80.81.20.80.2
Co content in liver1.01.22.0-1.2-1.40.0-1.2-1.1-1.2-1.30.4
Cu content in liver2.32.87.01.11.9-2.20.60.31.61.6-2.6
Fe content in liver0.20.30.5-0.7-0.7-0.0-0.5-0.4-0.3-0.70.2
K content in liver0.40.41.20.5-0.30.90.20.3-0.6-0.11.1
Mg content in liver0.30.30.60.80.20.60.50.5-0.20.30.7
Mn content in liver0.80.91.8-0.9-1.2-0.0-0.9-0.9-1.3-1.20.4
Na content in liver3.53.75.92.12.4-0.02.11.92.32.3-0.7
Rb content in liver0.40.50.80.70.80.30.80.80.90.90.0
Se content in liver0.10.10.20.3-0.0-0.5-0.3-0.4-0.40.1-0.4
Sr content in liver0.30.30.50.40.6-0.50.30.20.50.5-0.7
Zn content in liver0.40.41.00.50.8-0.80.30.20.70.7-1.0