Hub : Genes

Rnf7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	gene expression	ENSRNOG00000011663	0.05	0.03	1.5e-05	0.05	0.04	0.04	0.04	7.3e-06	2.5e-05	2.1e-05	3.2e-05
2	Liver	isoform ratio	ENSRNOT00000015821	0.11	0.07	2.9e-04	0.04	0.01	0.02	0.03	4.2e-05	9.0e-03	1.8e-03	2.9e-04
3	Liver	isoform ratio	ENSRNOT00000096041	0.09	0.06	5.8e-04	0.03	0.01	0.02	0.03	1.3e-04	1.4e-02	3.0e-03	7.5e-04
4	PL	gene expression	ENSRNOG00000011663	0.07	0.05	3.7e-03	0.03	0.04	0.06	0.06	1.3e-03	6.6e-04	2.3e-05	2.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
BMI with tail	2.4	7.9	15.0	-1.4	-2.7	2.7	3.9
BMI without tail	4.1	8.7	13.5	0.8	-3.2	3.2	3.7
Body weight	3.9	16.5	28.9	-0.3	-4.3	4.3	5.4
Epididymis fat weight	0.2	0.4	0.5	-0.7	-0.5	0.5	0.7
Glucose	0.1	0.1	0.4	-0.6	-0.1	0.1	0.3
Heart weight	0.3	0.4	1.1	-0.5	-0.4	0.4	1.0
Left kidney weight	2.1	6.1	11.1	-1.5	-2.4	2.4	3.3
Right kidney weight	2.0	5.7	10.7	-1.4	-2.2	2.2	3.3
Tail length	2.9	8.7	10.1	2.6	-3.2	3.2	2.8
Length with tail	1.5	5.5	6.8	1.3	-2.6	2.6	2.6
Length without tail	0.6	1.4	2.2	-0.7	-1.2	1.2	1.5
Liver weight, left	0.8	1.3	1.6	1.0	-1.3	1.3	1.0
Liver weight, right	0.3	0.5	1.1	-0.2	-0.6	0.6	1.0
Parametrial fat weight	0.9	1.7	2.9	1.7	-1.3	1.3	0.7
Retroperitoneal fat weight	1.3	4.3	5.5	1.2	-2.4	2.4	2.2
Intraocular pressure	1.0	1.4	2.4	0.3	-1.3	1.3	1.6
Extensor digitorum longus weight	1.1	4.4	9.3	-0.8	-2.0	2.0	3.0
Soleus weight	2.0	5.8	7.8	0.7	-2.8	2.8	2.7
Tibialis anterior weight	1.4	4.7	7.2	-0.0	-2.4	2.4	2.7
Tibia length	4.3	12.0	14.3	2.5	-3.8	3.8	3.6
Number of licking bursts	1.2	1.5	2.0	1.4	-1.3	1.3	0.7
Food consumed during 24 hour testing period	0.5	0.6	1.4	1.2	-0.7	0.7	0.3
Times rat made contact with spout	0.2	0.3	0.4	-0.2	-0.6	0.6	0.4
Mean time between licks in bursts	0.5	0.7	1.0	-1.0	0.8	-0.8	-0.6
Mean num. licks in bursts	0.8	0.9	2.8	-1.7	0.7	-0.7	-0.2
Std. dev. time between licks in bursts	2.0	2.4	2.6	-1.3	1.6	-1.6	-1.6
Water consumed over 24 hours	1.0	1.2	1.8	1.0	-1.3	1.3	0.6
Indifference point 0 sec	0.1	0.1	0.1	-0.2	-0.3	0.3	0.3
Indifference point AUC	3.4	4.0	5.6	-1.4	2.4	-2.4	-1.7
Indifference point function ln k	3.1	4.3	5.8	1.7	-2.4	2.4	1.7
Indifference point function log k	3.1	4.3	5.8	1.7	-2.4	2.4	1.7
Delay discounting total patch changes 0 sec	0.1	0.1	0.2	-0.2	-0.4	0.4	0.4
Delay discounting total patch changes 12 sec	3.9	5.2	6.4	-2.4	2.5	-2.5	-1.5
Delay discounting total patch changes 18 sec	0.6	0.8	1.1	-1.0	1.0	-1.0	-0.4
Delay discounting total patch changes 24 sec	0.5	0.6	0.8	-0.4	0.9	-0.9	-0.7
Delay discounting total patch changes 6 sec	0.9	1.4	1.7	-0.9	1.3	-1.3	-1.3
Delay discounting time to switch 0 sec	1.0	1.5	1.9	-0.0	1.4	-1.4	-1.4
Delay discounting water rate 0 sec	1.3	2.0	2.9	0.8	-1.7	1.7	1.2
Delay discounting water rate 12 sec	3.3	4.9	7.2	0.8	-2.7	2.7	2.1
Delay discounting water rate 18 sec	3.0	3.9	5.9	0.0	-2.2	2.2	2.4
Delay discounting water rate 24 sec	2.2	3.0	4.3	1.1	-2.1	2.1	1.5
Delay discounting water rate 6 sec	4.4	6.3	8.3	1.2	-2.9	2.9	2.7
Locomotor activity	1.0	1.7	2.3	0.4	-1.5	1.5	1.4
Locomotor testing distance	0.4	0.6	0.9	0.2	-0.9	0.9	0.8
Locomotor testing rearing	0.2	0.3	0.5	-0.0	-0.7	0.7	0.5
Light reinforcement 1	1.0	1.8	2.2	1.2	-1.5	1.5	1.3
Light reinforcement 2	1.0	1.3	1.4	1.1	-1.2	1.2	1.0
Reaction time number correct	0.0	0.0	0.0	0.1	-0.2	0.2	-0.1
Reaction time mean minus median	0.3	0.3	0.7	-0.8	0.6	-0.6	-0.0
Reaction time mean minus median AUC	0.1	0.1	0.3	-0.4	-0.0	0.0	0.5
Reaction time num false alarms	0.1	0.1	0.2	0.3	0.3	-0.3	-0.5
Reaction time num false alarms AUC	0.3	0.4	0.7	0.3	0.6	-0.6	-0.8
Reaction time trials correct on left	0.0	0.0	0.0	0.1	-0.2	0.2	-0.1
Reaction time trials on left	0.0	0.0	0.0	0.1	-0.2	0.2	-0.1
Reaction time mean	0.0	0.0	0.0	-0.1	0.2	-0.2	-0.1
Reaction time mean AUC	0.0	0.0	0.0	0.2	0.2	-0.2	-0.2
Median of all reaction times	0.0	0.0	0.1	0.3	0.1	-0.1	-0.2
Reaction time omissions	0.3	0.4	0.6	-0.6	0.7	-0.7	-0.5
Reaction time false alarm rate	0.1	0.1	0.2	0.4	0.3	-0.3	-0.4
Reaction time premature initiation rate	0.4	0.5	1.3	1.1	0.3	-0.3	-0.9
Reaction time premature initiations	0.3	0.4	0.7	0.8	0.3	-0.3	-0.9
Std. dev. reaction times	0.1	0.2	0.3	-0.5	0.5	-0.5	-0.3
Reaction time trials completed	0.0	0.0	0.0	0.1	-0.2	0.2	-0.1
Reaction time trials AUC	0.0	0.0	0.0	0.1	-0.1	0.1	-0.1
Social response proportion	0.2	0.2	0.4	-0.2	0.6	-0.6	-0.1
Social responses	0.1	0.1	0.2	0.4	0.2	-0.2	-0.2
Social time	0.0	0.0	0.2	0.1	-0.0	0.0	-0.4
Conditioned locomotion	2.5	3.0	3.8	-1.0	1.9	-1.9	-1.9
Cocaine response after cond. corrected	1.9	2.1	2.8	1.2	-1.7	1.7	1.2
Cocaine response after cond. not corrected	3.3	3.7	4.6	1.5	-2.1	2.1	1.8
Cocaine response before conditioning	0.7	0.9	0.9	0.9	-1.0	1.0	0.9
Saline control response	0.6	0.8	1.0	-1.0	-0.9	0.9	0.7
Condit. Reinf. active minus inactive responses	1.5	1.9	2.4	1.6	-1.4	1.4	1.2
Condit. Reinf. active-inactive response ratio	5.7	6.0	7.2	2.0	-2.7	2.7	2.4
Condit. Reinf. active responses	0.4	0.5	1.7	1.3	-0.4	0.4	0.2
Condit. Reinf. inactive responses	1.4	1.8	2.3	-0.4	1.5	-1.5	-1.5
Condit. Reinf. lever presses	2.0	2.7	3.2	1.5	-1.8	1.8	1.4
Condit. Reinf. lever reinforcers received	0.2	0.3	1.1	1.0	-0.3	0.3	0.2
Pavlov. Cond. lever latency	0.9	1.2	2.5	0.9	0.9	-0.9	-1.6
Pavlov. Cond. magazine entry latency	0.8	1.0	1.6	-1.1	-0.7	0.7	1.3
Pavlov. Cond. change in total contacts	2.0	2.8	5.0	-0.5	-1.7	1.7	2.2
Pavlov. Cond. index score	1.0	1.3	2.4	-0.5	-1.1	1.1	1.5
Pavlov. Cond. latency score	0.9	1.2	2.3	-0.6	-1.0	1.0	1.5
Pavlov. Cond. lever contacts	1.1	1.5	2.8	-0.6	-1.2	1.2	1.7
Pavlov. Cond. magazine entry number	0.3	0.3	0.7	0.6	0.4	-0.4	-0.8
Pavlov. Cond. intertrial magazine entries	2.4	3.1	5.6	0.8	1.7	-1.7	-2.4
Pavlov. Cond. lever-magazine prob. diff.	0.9	1.2	2.3	-0.7	-1.0	1.0	1.5
Pavlov. Cond. response bias	0.8	1.1	2.1	-0.8	-1.0	1.0	1.4
Conditioned reinforcement - actives	0.3	0.3	0.3	0.5	-0.5	0.5	0.5
Conditioned reinforcement - inactives	0.1	0.1	0.3	0.5	-0.3	0.3	0.4
Conditioned locomotion	0.2	0.3	0.9	-0.9	0.0	-0.0	0.5
Intermittent access intake day 1-15 change	0.1	0.1	0.2	0.4	-0.3	0.3	0.3
Intermittent access intake escalation	0.0	0.0	0.0	-0.0	0.1	-0.1	0.0
Intermittent access intake escalation 2	0.2	0.2	0.5	0.7	0.2	-0.2	-0.4
Intermitt. access day 1 inactive lever presses	2.2	2.4	2.9	-1.7	1.7	-1.7	-0.9
Intermitt. access day 15 inactive lever presses	0.2	0.2	0.3	-0.2	0.5	-0.5	-0.3
Intermitt. access escalation Index	0.6	0.6	2.1	1.4	-0.3	0.3	-0.2
Intermittent access day 1 total infusions	0.1	0.1	0.2	-0.1	-0.3	0.3	0.4
Intermittent access day 15 total infusions	0.6	0.7	0.9	0.3	-0.9	0.9	1.0
Intermittent access terminal intake (last 3 days)	0.8	0.8	1.1	0.4	-1.0	1.0	1.1
Intermittent access total infusions	0.1	0.1	0.1	-0.2	-0.2	0.2	0.4
Intermittent access day 1 locomotion	0.2	0.2	0.3	-0.6	-0.2	0.2	0.5
Intermittent access day 15 total locomotion	0.1	0.1	0.2	-0.5	0.2	-0.2	-0.0
Intermittent access total locomotion	0.6	0.6	1.1	-1.0	0.8	-0.8	-0.4
Intermittent access standard deviation	0.1	0.1	0.1	0.2	-0.4	0.4	0.3
Cocaine induced anxiety	0.8	0.9	1.2	-0.7	1.1	-1.1	-0.9
Post-drug Anxiety	0.2	0.2	0.3	-0.6	0.4	-0.4	-0.3
Baseline Anxiety	0.2	0.2	0.7	-0.8	0.1	-0.1	0.1
Lifetime Intake	0.1	0.1	0.2	-0.1	-0.3	0.3	0.5
Incentive Sensitization - Responses	0.3	0.3	0.4	0.3	-0.7	0.7	0.6
Incentive Sensitization - Breakpoint	0.4	0.4	0.5	0.3	-0.7	0.7	0.6
Progressive ratio test 1 active lever presses	0.1	0.1	0.3	-0.6	0.1	-0.1	0.2
Progressive ratio test 1 breakpoint	0.2	0.2	0.8	-0.9	0.2	-0.2	0.3
Progressive ratio test 1 inactive lever presses	0.5	0.5	0.7	-0.7	0.8	-0.8	-0.4
Progressive ratio test 2 active lever presses	0.1	0.1	0.1	-0.3	-0.1	0.1	0.3
Progressive ratio test 2 breakpoint	0.0	0.0	0.0	-0.0	-0.1	0.1	0.2
Progressive ratio test 2 inactive lever presses	0.1	0.1	0.3	0.5	0.1	-0.1	-0.2
Total sessions with >9 infusions	0.4	0.4	0.7	0.2	-0.7	0.7	0.8
Short access day 1 total inactive lever presses	2.6	2.8	3.8	-1.1	2.0	-2.0	-1.6
Short access day 10 total inactive lever presses	2.0	2.3	3.2	-1.8	1.6	-1.6	-0.9
Short access day 1 total infusions	0.1	0.1	0.1	-0.3	0.4	-0.4	-0.1
Short access day 10 total infusions	0.2	0.2	0.4	-0.4	-0.4	0.4	0.6
Short access total infusions	0.1	0.1	0.3	-0.5	0.2	-0.2	0.1
Short access day 1 locomotion	1.1	1.2	1.6	-0.8	1.2	-1.2	-1.0
Short access day 10 total locomotion	2.2	2.4	3.4	-1.8	1.6	-1.6	-0.9
Short access total locomotion	0.6	0.7	1.6	-1.3	0.7	-0.7	-0.2
Compulsive drug intake	0.5	0.5	0.9	0.8	0.4	-0.4	-1.0
One hour access (0.3 mA shock)	0.1	0.2	0.5	0.7	-0.2	0.2	0.0
One hour access (shock baseline)	0.3	0.3	0.5	0.7	-0.6	0.6	0.5
Number of responses in last shaping day	0.2	0.3	0.4	0.2	-0.5	0.5	0.7
Context. condit. distance diff. score	2.0	2.5	3.1	-1.4	1.8	-1.8	-1.4
Locomotion velocity, session 1	0.3	0.3	0.8	-0.9	0.4	-0.4	0.5
Locomotion distance, session 1	1.0	1.3	3.4	-1.8	0.0	-0.0	1.3
Locomotion velocity, session 2	1.4	1.7	3.0	-1.6	-0.8	0.8	1.7
Locomotion distance, session 2	2.8	4.1	8.6	-1.6	-1.6	1.6	2.9
Locomotion velocity, session 3	1.4	1.7	2.0	1.0	-1.4	1.4	1.3
Locomotion distance, session 3	0.5	0.6	1.5	0.0	-0.6	0.6	1.2
Stereotopy head waving bouts, day 3	6.0	7.1	9.8	3.1	-2.9	2.9	1.4
Stereotopy head waving duration, day 3	3.9	4.7	6.2	2.5	-2.4	2.4	1.0
Locomotion velocity, session 7	0.6	0.7	2.5	-1.6	0.1	-0.1	0.6
Locomotion distance, session 7	0.2	0.3	1.0	-1.0	0.0	-0.0	0.5
Stereotopy head waving bouts, day 7	2.8	3.1	6.9	1.1	1.5	-1.5	-2.6
Stereotopy head waving duration, day 7	1.9	2.3	5.0	1.7	0.8	-0.8	-2.2
Locomotion velocity, session 8	0.9	1.1	2.2	-1.5	1.1	-1.1	-0.2
Locomotion distance, session 8	0.8	1.1	3.6	-1.9	0.6	-0.6	0.4
Degree of sensitization distance	0.7	0.7	1.2	-1.1	0.7	-0.7	-0.8
Degree of sensitization stereotypy	5.9	6.5	10.0	-0.6	2.8	-2.8	-3.2
Condit. Reinf. active minus inactive responses	0.6	0.7	0.9	0.3	-1.0	1.0	0.8
Condit. Reinf. active-inactive response ratio	1.0	1.1	1.7	-0.9	-1.0	1.0	1.3
Condit. Reinf. active responses	0.3	0.4	0.6	0.4	-0.8	0.8	0.6
Condit. Reinf. inactive responses	0.3	0.3	1.2	1.1	-0.1	0.1	-0.3
Incentive salience index mean	1.2	1.4	2.3	-0.2	-1.3	1.3	1.5
Condit. Reinf. lever presses	1.2	1.6	3.1	-0.7	-1.2	1.2	1.8
Time in familiar zone, hab. session 1	2.6	2.5	4.8	2.0	0.8	-0.8	-2.2
Time in novel zone, hab. session 1	2.8	2.7	6.2	-1.6	-1.0	1.0	2.5
Total zone transitions, hab. session 1	0.7	0.9	3.0	-1.7	0.4	-0.4	0.6
Total locomotion distance, hab. session 1	0.5	0.7	2.2	-1.5	0.2	-0.2	0.8
Locomotion velocity, hab. session 1	0.8	1.2	3.7	-1.9	0.7	-0.7	0.3
Time in familiar zone, hab. session 2	1.1	1.2	1.7	-0.4	1.3	-1.3	-1.0
Time in novel zone, hab. session 2	0.7	0.7	0.9	-0.5	-0.9	0.9	1.0
Total zone transitions, hab. session 2	1.0	1.3	2.5	-1.3	-0.7	0.7	1.6
Total locomotion distance, hab. session 2	0.6	0.8	1.7	-0.9	-0.5	0.5	1.3
Locomotion velocity, hab. session 2	0.5	0.7	1.5	-1.0	-0.5	0.5	1.2
Novel to familiar place preference ratio	1.2	1.3	1.9	-1.4	1.1	-1.1	-0.9
Novelty place preference	0.6	0.6	1.4	-1.2	0.7	-0.7	-0.5
Time in novel zone, NPP test	0.5	0.5	1.4	-1.2	0.5	-0.5	-0.3
Total zone transitions, NPP test	3.6	5.2	11.3	-2.0	-1.6	1.6	3.4
Total locomotion distance, NPP test	2.1	2.9	6.6	-1.0	-1.4	1.4	2.6
Locomotion velocity, NPP test	1.9	2.7	6.1	-1.1	-1.3	1.3	2.5
Pavlov. Cond. lever latency	0.8	1.1	2.3	1.5	0.5	-0.5	-1.2
Pavlov. Cond. magazine entry latency	0.6	0.8	1.9	-1.4	-0.4	0.4	0.9
Pavlov. Cond. change in total contacts	0.3	0.4	0.7	-0.9	-0.3	0.3	0.7
Pavlov. Cond. index score	0.7	0.9	2.8	-1.7	-0.3	0.3	0.9
Pavlov. Cond. latency score	0.9	1.2	2.6	-1.6	-0.5	0.5	1.2
Pavlov. Cond. lever contacts	0.8	0.9	3.3	-1.8	0.1	-0.1	0.6
Pavlov. Cond. magazine entry number	0.3	0.3	1.2	1.1	-0.1	0.1	-0.3
Pavlov. Cond. intertrial magazine entries	0.5	0.6	2.1	1.5	0.0	-0.0	-0.7
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.9	2.9	-1.7	-0.1	0.1	0.8
Pavlov. Cond. response bias	0.2	0.2	0.7	-0.8	-0.0	0.0	0.4
Bone: apparent density	0.2	0.3	0.5	0.1	0.5	-0.5	-0.7
Bone surface	0.1	0.2	0.7	0.8	0.1	-0.1	-0.3
Bone volume	0.1	0.1	0.2	0.4	0.3	-0.3	-0.3
Bone: connectivity density	1.0	1.5	2.5	-0.0	1.3	-1.3	-1.6
Bone: cortical apparent density	1.3	1.7	2.3	-0.7	1.5	-1.5	-1.3
Bone: cortical area	0.7	1.1	3.2	-1.8	0.8	-0.8	0.1
Bone: cortical porosity	1.8	1.9	5.2	-2.3	1.1	-1.1	-0.4
Bone: cortical porosity	3.4	3.7	8.0	-2.8	1.7	-1.7	-0.9
Bone: cortical thickness	0.4	0.6	1.8	-1.4	0.5	-0.5	0.3
Bone: cortical thickness	0.4	0.4	0.6	-0.8	0.8	-0.8	-0.1
Bone: cortical tissue density	1.3	1.6	2.2	-0.7	1.5	-1.5	-1.3
Bone: elastic displacement	1.1	1.2	3.5	-1.9	0.6	-0.6	0.7
Bone: elastic work	0.5	0.6	1.5	-1.2	0.1	-0.1	0.9
Bone: endosteal estimation	0.2	0.5	0.8	-0.1	-0.8	0.8	0.9
Bone: endosteal perimeter	0.3	0.6	2.1	-1.5	0.1	-0.1	0.5
Bone: final force	0.5	0.7	0.8	0.7	-0.9	0.9	0.9
Bone: final moment	0.8	1.3	1.6	0.9	-1.3	1.3	1.2
Bone: marrow area	0.3	0.7	1.0	-0.1	-0.9	0.9	1.0
Bone: maximum diameter	1.0	1.8	6.1	-2.5	0.7	-0.7	0.3
Bone: maximum force	0.1	0.2	0.4	-0.3	-0.3	0.3	0.6
Bone: maximum moment	0.2	0.4	0.7	-0.2	-0.6	0.6	0.9
Bone: minimum diameter	0.1	0.3	0.5	-0.7	0.5	-0.5	-0.3
Bone: periosteal estimation	0.2	0.4	1.0	-1.0	-0.3	0.3	0.8
Bone: periosteal perimeter	1.3	2.2	5.2	-2.3	1.3	-1.3	-0.4
Bone: post-yield work	0.3	0.4	0.8	0.9	-0.7	0.7	0.2
Bone: stiffness	0.0	0.0	0.1	0.1	0.1	-0.1	-0.3
Bone: tissue strength	5.1	5.0	6.2	2.0	-2.5	2.5	1.9
Bone: trabecular number	1.0	1.6	2.4	0.0	1.4	-1.4	-1.5
Bone: trabecular spacing	0.1	0.1	0.1	0.3	-0.4	0.4	-0.0
Bone: trabecular thickness	0.2	0.3	0.4	0.2	-0.5	0.5	0.6
Bone: trabecular tissue density	0.5	0.7	2.0	-1.4	-0.4	0.4	0.8
Breakpoint value in progressive ratio session	1.4	1.6	3.0	0.2	1.3	-1.3	-1.7
Distance traveled before self-admin	1.0	1.1	1.8	-1.3	-0.9	0.9	1.0
Distance traveled after self-admin	0.2	0.2	0.7	-0.8	-0.1	0.1	0.3
Delta time in closed arm before/after self-admin	3.4	3.3	4.5	-1.5	2.1	-2.1	-1.4
Delta time in open arm before/after self-admin	0.2	0.2	0.6	-0.8	0.2	-0.2	-0.3
Diff in mean of infusions in LGA sessions	0.3	0.3	0.6	0.7	0.1	-0.1	-0.8
Extinction: sum of active levers before priming	3.1	3.2	4.0	-1.8	2.0	-2.0	-1.2
Active lever presses in extinction session 6	1.5	1.5	1.7	-1.3	1.3	-1.3	-1.0
Delta distance traveled before/after self-admin	1.1	1.2	1.7	-0.1	1.3	-1.3	-1.1
Delta ambulatory time before/after self-admin	0.8	0.8	1.2	0.3	1.1	-1.1	-0.9
Time in closed arm before self-admin	3.1	3.5	4.3	1.8	-2.1	2.1	1.4
Time in closed arm after self-admin	0.0	0.0	0.1	0.2	-0.0	0.0	0.2
Time in open arm before self-admin	0.1	0.2	0.2	-0.0	0.5	-0.5	-0.4
Time in open arm after self-admin	1.8	2.0	2.4	-1.0	1.5	-1.5	-1.6
Sum of active levers in priming session hrs 5-6	1.1	1.0	2.6	-1.6	0.9	-0.9	-0.4
Time to tail flick, vehicle, before self-admin	0.6	0.6	1.1	1.1	-0.7	0.7	0.3
Time to tail flick, vehicle, after self-admin	0.2	0.2	0.7	-0.2	-0.3	0.3	0.8
Time to tail flick, test, before self-admin	1.0	0.9	2.8	1.7	-0.7	0.7	0.2
Time to tail flick, test, after self-admin	5.3	5.5	7.1	1.7	-2.7	2.7	2.2
Delta time to tail flick, vehicle, before/after SA	0.3	0.3	0.7	-0.8	0.2	-0.2	0.5
Delta time to tail flick, test, before/after SA	3.3	3.0	4.2	0.8	-2.1	2.1	1.7
Ambulatory time before self-admin	1.0	1.0	1.1	-1.0	-1.0	1.0	1.0
Ambulatory time after self-admin	0.2	0.2	0.7	-0.8	0.2	-0.2	0.1
Total heroin consumption	0.3	0.4	0.5	0.2	-0.7	0.7	0.6
Area under the delay curve	0.2	0.2	0.7	0.8	-0.3	0.3	-0.1
Delay disc. indifference point, 0s delay	0.5	0.6	1.8	1.3	-0.2	0.2	-0.7
Delay disc. indifference point, 16s delay	0.9	0.9	1.5	0.4	-1.2	1.2	0.5
Delay disc. indifference point, 2s delay	1.7	1.9	2.2	1.1	-1.5	1.5	1.5
Delay disc. indifference point, 24s delay	1.2	1.1	1.6	-0.6	1.3	-1.3	-0.9
Delay disc. indifference point, 4s delay	1.1	1.1	3.8	2.0	-0.6	0.6	-0.2
Delay disc. indifference point, 8s delay	0.1	0.1	0.2	0.1	0.4	-0.4	-0.4
Delay discount exponential model param	0.2	0.2	0.7	-0.8	0.2	-0.2	0.0
Delay discount hyperbolic model param	0.3	0.3	0.9	-1.0	0.4	-0.4	-0.2
Fecal boli incidents, locomotor time 1	1.1	1.2	2.2	-0.3	-1.1	1.1	1.5
Change in fecal boli incidents, locomotor task	0.4	0.4	0.8	-0.9	-0.2	0.2	0.8
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.4	-0.7	0.4	-0.4	-0.1
Bouts of movement, locomotor time 1	1.5	1.6	1.8	1.3	-1.3	1.3	1.1
Total resting periods, locomotor time 1	1.8	2.0	2.4	1.2	-1.5	1.5	1.4
Rest time, locomotor task time 1	0.4	0.5	1.2	-0.8	-0.0	0.0	1.1
Distance moved, locomotor task time 1	0.2	0.2	0.6	0.3	0.1	-0.1	-0.8
Vertical activity count, locomotor time 1	1.0	1.0	1.8	0.1	1.0	-1.0	-1.4
Time >=10cm from walls, locomotor time 2	0.5	0.6	1.0	-0.0	0.8	-0.8	-1.0
Bouts of movement, locomotor time 2	0.2	0.3	0.6	-0.7	0.5	-0.5	-0.1
Total resting periods, locomotor time 2	0.1	0.1	0.4	-0.6	0.2	-0.2	0.3
Rest time, locomotor task time 2	0.1	0.1	0.4	-0.4	-0.0	0.0	0.7
Distance moved, locomotor task time 2	0.2	0.2	0.6	0.8	0.1	-0.1	-0.5
Vertical activity count, locomotor time 2	1.5	1.7	2.2	-0.4	1.5	-1.5	-1.4
Weight adjusted by age	0.7	0.8	1.5	-0.3	-0.9	0.9	1.2
Seeking ratio, delayed vs. immediate footshock	9.5	10.9	13.5	-2.5	3.7	-3.7	-3.2
Locomotion in novel chamber	0.2	0.3	0.5	0.7	0.1	-0.1	-0.7
Locomotion in novel chamber post-restriction	0.4	0.5	1.9	1.4	-0.3	0.3	-0.1
Progressive ratio	0.3	0.4	0.8	-0.8	-0.3	0.3	0.9
Food seeking constrained by brief footshock	0.2	0.3	0.5	-0.4	0.7	-0.7	-0.1
Seeking ratio, punishment vs. effort	0.1	0.2	0.3	0.6	0.3	-0.3	-0.5
Run reversals in cocaine runway, females	0.6	0.6	0.8	0.9	-0.9	0.9	0.4
Run reversals in cocaine runway, males	0.4	0.4	0.7	-0.2	-0.7	0.7	0.8
Latency to leave start box in cocaine runway	1.2	1.4	2.4	0.8	1.1	-1.1	-1.6
Latency to leave start box in cocaine runway, F	0.8	0.9	1.9	0.9	0.7	-0.7	-1.4
Latency to leave start box in cocaine runway, M	0.5	0.5	0.6	0.6	0.7	-0.7	-0.8
Cd content in liver	0.0	0.0	0.1	-0.0	-0.2	0.2	-0.1
Co content in liver	1.2	1.4	2.1	-1.0	1.5	-1.5	-0.6
Cu content in liver	1.2	1.4	3.7	1.9	-1.0	1.0	0.4
Fe content in liver	1.1	1.3	2.2	1.5	-1.1	1.1	0.7
K content in liver	0.4	0.4	0.5	0.3	-0.7	0.7	0.6
Mg content in liver	0.3	0.4	0.5	-0.1	-0.7	0.7	0.7
Mn content in liver	0.4	0.4	1.4	-1.2	0.3	-0.3	0.1
Na content in liver	0.1	0.1	0.2	-0.2	-0.5	0.5	0.1
Rb content in liver	0.8	1.0	1.3	0.8	-1.1	1.1	0.9
Se content in liver	0.2	0.3	0.9	1.0	-0.2	0.2	-0.2
Sr content in liver	0.4	0.4	0.9	0.9	-0.6	0.6	0.1
Zn content in liver	0.5	0.5	1.4	0.0	-0.6	0.6	1.2