Hub : Genes

Slc1a7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	PL	alternative polyA	ENSRNOT00000016557	0.05	0.04	5.9e-03	-0	0.01	0.01	0	3.6e-01	6.9e-02	8.1e-02	3.3e-01
2	PL	alternative polyA	ENSRNOT00000016557	0.06	0.04	1.2e-03	0.01	0.03	0.01	0.02	2.3e-02	2.9e-03	3.1e-02	1.5e-02
3	PL	alternative polyA	ENSRNOT00000077808	0.06	0.04	1.1e-03	0.01	0.03	0.01	0.02	2.2e-02	2.8e-03	2.9e-02	1.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
BMI with tail	1.0	3.4	3.6	-1.7	-1.9	1.9
BMI without tail	0.0	0.0	0.0	-0.1	0.1	-0.1
Body weight	0.8	3.5	3.6	-1.8	-1.9	1.9
Epididymis fat weight	0.1	0.3	0.3	0.4	0.5	-0.5
Glucose	0.0	0.0	0.0	-0.0	0.1	-0.1
Heart weight	1.3	1.8	2.0	-1.3	-1.4	1.4
Left kidney weight	9.5	27.3	27.8	-5.1	-5.3	5.3
Right kidney weight	6.7	19.0	20.2	-4.1	-4.5	4.5
Tail length	0.3	0.8	1.0	0.7	1.0	-1.0
Length with tail	0.0	0.0	0.0	-0.2	-0.2	0.2
Length without tail	0.6	1.3	1.5	-0.9	-1.2	1.2
Liver weight, left	0.5	0.7	0.8	-0.8	-0.9	0.9
Liver weight, right	0.0	0.1	0.1	-0.2	-0.3	0.3
Parametrial fat weight	0.1	0.2	0.4	0.6	0.4	-0.4
Retroperitoneal fat weight	0.2	0.7	1.1	1.0	0.7	-0.7
Intraocular pressure	0.1	0.1	0.1	-0.2	-0.3	0.3
Extensor digitorum longus weight	1.5	5.9	6.2	-2.3	-2.5	2.5
Soleus weight	2.9	8.4	8.5	-2.9	-2.9	2.9
Tibialis anterior weight	4.8	16.6	17.9	-3.8	-4.2	4.2
Tibia length	0.1	0.3	0.3	-0.5	-0.6	0.6
Number of licking bursts	0.1	0.2	0.3	-0.1	-0.5	0.5
Food consumed during 24 hour testing period	0.2	0.2	0.5	-0.7	-0.3	0.3
Times rat made contact with spout	0.5	0.6	1.0	-1.0	-0.6	0.6
Mean time between licks in bursts	1.2	1.7	2.0	1.1	1.4	-1.4
Mean num. licks in bursts	0.5	0.6	1.2	-1.1	-0.5	0.5
Std. dev. time between licks in bursts	3.9	4.6	4.7	2.2	2.1	-2.1
Water consumed over 24 hours	1.6	1.9	3.5	-1.9	-1.1	1.1
Indifference point 0 sec	0.6	1.0	1.4	-1.2	-0.9	0.9
Indifference point AUC	0.0	0.0	0.0	-0.1	0.2	-0.2
Indifference point function ln k	0.5	0.6	0.7	-0.8	-0.8	0.8
Indifference point function log k	0.5	0.6	0.7	-0.8	-0.8	0.8
Delay discounting total patch changes 0 sec	0.5	0.8	1.1	-1.1	-0.8	0.8
Delay discounting total patch changes 12 sec	1.1	1.4	1.6	1.0	1.3	-1.3
Delay discounting total patch changes 18 sec	0.3	0.5	0.6	-0.8	-0.6	0.6
Delay discounting total patch changes 24 sec	0.6	0.8	0.8	-0.8	-0.9	0.9
Delay discounting total patch changes 6 sec	0.2	0.3	0.8	-0.9	-0.4	0.4
Delay discounting time to switch 0 sec	2.5	3.8	5.1	2.3	1.8	-1.8
Delay discounting water rate 0 sec	2.7	4.3	4.7	-2.2	-2.0	2.0
Delay discounting water rate 12 sec	4.3	6.5	7.5	-2.7	-2.4	2.4
Delay discounting water rate 18 sec	0.0	0.0	0.1	0.3	0.0	-0.0
Delay discounting water rate 24 sec	0.1	0.1	0.2	-0.3	-0.4	0.4
Delay discounting water rate 6 sec	1.2	1.8	1.9	-1.2	-1.4	1.4
Locomotor activity	0.0	0.0	0.0	-0.2	0.1	-0.2
Locomotor testing distance	0.3	0.6	1.2	-1.1	-0.5	0.5
Locomotor testing rearing	0.2	0.3	0.7	-0.8	-0.2	0.2
Light reinforcement 1	0.1	0.2	0.3	-0.3	-0.5	0.5
Light reinforcement 2	1.6	2.1	2.2	-1.4	-1.5	1.5
Reaction time number correct	0.0	0.0	0.0	-0.0	-0.1	0.2
Reaction time mean minus median	0.5	0.6	0.8	0.6	0.9	-0.9
Reaction time mean minus median AUC	0.3	0.4	0.5	0.4	0.7	-0.7
Reaction time num false alarms	0.6	0.9	1.0	-1.0	-0.9	0.9
Reaction time num false alarms AUC	1.3	1.9	2.3	-1.5	-1.3	1.3
Reaction time trials correct on left	0.0	0.0	0.0	-0.0	-0.1	0.2
Reaction time trials on left	0.0	0.0	0.0	-0.0	-0.1	0.1
Reaction time mean	1.2	1.6	1.7	1.3	1.2	-1.3
Reaction time mean AUC	1.4	1.9	2.0	1.4	1.3	-1.4
Median of all reaction times	1.6	2.1	2.6	1.6	1.4	-1.4
Reaction time omissions	0.4	0.6	0.7	0.6	0.8	-0.8
Reaction time false alarm rate	1.3	1.8	2.3	-1.5	-1.3	1.3
Reaction time premature initiation rate	0.2	0.2	0.3	0.3	0.6	-0.6
Reaction time premature initiations	0.2	0.3	0.4	0.4	0.6	-0.6
Std. dev. reaction times	0.3	0.4	0.6	0.4	0.7	-0.8
Reaction time trials completed	0.0	0.0	0.0	-0.0	-0.1	0.1
Reaction time trials AUC	0.1	0.1	0.1	-0.2	-0.3	0.3
Social response proportion	0.7	0.7	0.8	0.8	0.9	-0.9
Social responses	2.0	2.6	2.7	1.5	1.6	-1.7
Social time	0.0	0.0	0.1	-0.3	-0.1	0.1
Conditioned locomotion	0.1	0.1	0.1	0.1	-0.3	0.3
Cocaine response after cond. corrected	2.5	2.8	3.5	-1.9	-1.6	1.6
Cocaine response after cond. not corrected	4.0	4.4	5.4	-2.3	-2.0	2.0
Cocaine response before conditioning	0.2	0.3	0.3	-0.6	-0.5	0.5
Saline control response	0.2	0.3	0.8	-0.9	-0.3	0.3
Condit. Reinf. active minus inactive responses	0.7	0.9	1.7	-1.3	-0.7	0.7
Condit. Reinf. active-inactive response ratio	0.6	0.6	1.4	-1.2	-0.4	0.5
Condit. Reinf. active responses	0.6	0.8	1.3	-1.2	-0.7	0.7
Condit. Reinf. inactive responses	0.2	0.3	0.4	-0.3	-0.6	0.6
Condit. Reinf. lever presses	0.1	0.2	0.3	0.1	0.5	-0.5
Condit. Reinf. lever reinforcers received	0.4	0.6	1.0	-1.0	-0.6	0.6
Pavlov. Cond. lever latency	0.1	0.2	0.3	-0.1	-0.5	0.5
Pavlov. Cond. magazine entry latency	1.3	1.5	2.0	0.8	1.4	-1.4
Pavlov. Cond. change in total contacts	0.2	0.3	0.4	0.1	0.6	-0.6
Pavlov. Cond. index score	0.7	0.9	1.2	0.5	1.1	-1.1
Pavlov. Cond. latency score	0.5	0.7	0.9	0.4	1.0	-1.0
Pavlov. Cond. lever contacts	0.1	0.1	0.1	-0.1	0.4	-0.4
Pavlov. Cond. magazine entry number	2.4	2.9	3.5	-1.3	-1.9	1.9
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.4	0.7	0.0	-0.0
Pavlov. Cond. lever-magazine prob. diff.	0.7	1.0	1.3	0.5	1.1	-1.1
Pavlov. Cond. response bias	0.6	0.8	1.1	0.5	1.0	-1.1
Conditioned reinforcement - actives	3.0	2.9	3.4	-1.8	-1.6	1.6
Conditioned reinforcement - inactives	0.3	0.4	0.4	-0.6	-0.6	0.6
Conditioned locomotion	1.2	1.4	2.0	-1.4	-1.1	1.1
Intermittent access intake day 1-15 change	1.8	1.8	2.0	-1.4	-1.3	1.3
Intermittent access intake escalation	1.5	1.5	1.9	-1.4	-1.1	1.1
Intermittent access intake escalation 2	0.1	0.1	0.2	-0.5	-0.2	0.2
Intermitt. access day 1 inactive lever presses	2.3	2.5	2.6	-1.6	-1.5	1.6
Intermitt. access day 15 inactive lever presses	0.6	0.7	0.8	-0.6	-0.9	0.9
Intermitt. access escalation Index	0.4	0.4	0.5	-0.3	-0.7	0.7
Intermittent access day 1 total infusions	0.2	0.2	0.2	-0.3	-0.5	0.5
Intermittent access day 15 total infusions	1.4	1.6	1.7	-1.2	-1.3	1.3
Intermittent access terminal intake (last 3 days)	0.5	0.5	0.5	-0.7	-0.7	0.7
Intermittent access total infusions	0.8	0.8	0.9	-0.9	-0.9	0.9
Intermittent access day 1 locomotion	0.6	0.6	0.7	-0.6	-0.8	0.8
Intermittent access day 15 total locomotion	0.2	0.2	0.2	-0.4	-0.4	0.4
Intermittent access total locomotion	0.7	0.8	0.9	-0.8	-0.9	0.9
Intermittent access standard deviation	4.5	4.7	5.0	-2.2	-2.2	2.2
Cocaine induced anxiety	0.1	0.1	0.2	-0.1	-0.4	0.4
Post-drug Anxiety	0.2	0.2	0.5	0.7	0.3	-0.3
Baseline Anxiety	0.0	0.0	0.0	-0.1	-0.1	0.1
Lifetime Intake	0.8	0.9	0.9	-0.9	-1.0	1.0
Incentive Sensitization - Responses	0.0	0.0	0.0	-0.0	-0.1	0.1
Incentive Sensitization - Breakpoint	0.1	0.1	0.1	-0.2	-0.3	0.3
Progressive ratio test 1 active lever presses	0.3	0.3	0.4	-0.6	-0.6	0.6
Progressive ratio test 1 breakpoint	0.6	0.6	0.6	-0.8	-0.8	0.8
Progressive ratio test 1 inactive lever presses	1.3	1.4	1.6	-1.3	-1.1	1.2
Progressive ratio test 2 active lever presses	1.3	1.4	1.6	-1.3	-1.2	1.2
Progressive ratio test 2 breakpoint	1.3	1.5	1.5	-1.2	-1.2	1.2
Progressive ratio test 2 inactive lever presses	1.3	1.5	1.6	-1.1	-1.3	1.3
Total sessions with >9 infusions	0.1	0.1	0.2	0.4	0.4	-0.4
Short access day 1 total inactive lever presses	5.1	5.7	6.1	-2.2	-2.5	2.5
Short access day 10 total inactive lever presses	2.7	3.0	3.1	-1.8	-1.7	1.7
Short access day 1 total infusions	0.3	0.3	0.4	-0.2	-0.6	0.6
Short access day 10 total infusions	0.7	0.8	0.9	-0.8	-1.0	1.0
Short access total infusions	0.7	0.8	0.9	-0.7	-0.9	0.9
Short access day 1 locomotion	2.3	2.5	2.5	-1.5	-1.6	1.6
Short access day 10 total locomotion	1.3	1.4	1.4	-1.1	-1.2	1.2
Short access total locomotion	0.5	0.5	0.5	-0.7	-0.7	0.7
Compulsive drug intake	0.1	0.1	0.1	0.4	0.4	-0.4
One hour access (0.3 mA shock)	0.1	0.1	0.1	0.3	0.3	-0.3
One hour access (shock baseline)	0.4	0.5	0.5	-0.7	-0.7	0.7
Number of responses in last shaping day	2.4	2.5	2.7	-1.4	-1.6	1.6
Context. condit. distance diff. score	0.0	0.0	0.1	0.1	0.2	-0.2
Locomotion velocity, session 1	2.7	3.0	3.5	1.9	1.6	-1.6
Locomotion distance, session 1	0.0	0.0	0.0	0.2	0.0	-0.0
Locomotion velocity, session 2	2.6	3.1	3.7	1.9	1.7	-1.7
Locomotion distance, session 2	0.6	0.8	1.0	-1.0	-0.8	0.8
Locomotion velocity, session 3	0.4	0.5	0.5	0.7	0.7	-0.7
Locomotion distance, session 3	0.2	0.2	0.4	-0.6	-0.3	0.3
Stereotopy head waving bouts, day 3	0.0	0.0	0.1	0.4	-0.0	0.0
Stereotopy head waving duration, day 3	0.1	0.1	0.4	0.6	0.2	-0.2
Locomotion velocity, session 7	0.0	0.0	0.0	-0.2	0.1	-0.1
Locomotion distance, session 7	0.1	0.1	0.4	-0.6	0.0	-0.0
Stereotopy head waving bouts, day 7	1.2	1.4	1.8	1.3	1.1	-1.1
Stereotopy head waving duration, day 7	1.9	2.3	2.9	1.7	1.4	-1.4
Locomotion velocity, session 8	1.6	1.9	1.9	1.3	1.4	-1.4
Locomotion distance, session 8	0.1	0.2	0.4	-0.6	-0.3	0.3
Degree of sensitization distance	0.1	0.1	0.2	-0.4	-0.2	0.2
Degree of sensitization stereotypy	0.9	1.0	1.2	1.1	0.9	-0.9
Condit. Reinf. active minus inactive responses	0.9	1.0	1.2	-1.1	-0.9	0.9
Condit. Reinf. active-inactive response ratio	1.2	1.3	1.7	-1.3	-1.1	1.1
Condit. Reinf. active responses	1.0	1.2	1.3	-1.0	-1.1	1.1
Condit. Reinf. inactive responses	0.1	0.1	0.2	0.4	0.1	-0.1
Incentive salience index mean	2.4	2.9	3.1	-1.8	-1.7	1.7
Condit. Reinf. lever presses	1.9	2.6	2.6	-1.6	-1.6	1.6
Time in familiar zone, hab. session 1	0.2	0.2	0.2	0.4	0.4	-0.4
Time in novel zone, hab. session 1	0.0	0.0	0.0	-0.2	0.2	-0.2
Total zone transitions, hab. session 1	0.0	0.1	0.2	0.4	0.1	-0.1
Total locomotion distance, hab. session 1	0.3	0.5	0.6	-0.4	-0.8	0.8
Locomotion velocity, hab. session 1	0.1	0.2	0.2	-0.0	-0.5	0.5
Time in familiar zone, hab. session 2	0.4	0.4	0.6	0.2	0.7	-0.7
Time in novel zone, hab. session 2	0.1	0.2	0.2	-0.3	-0.4	0.4
Total zone transitions, hab. session 2	0.1	0.1	0.1	-0.4	-0.2	0.2
Total locomotion distance, hab. session 2	0.5	0.7	0.7	-0.8	-0.8	0.8
Locomotion velocity, hab. session 2	0.6	0.8	0.8	-0.8	-0.9	0.9
Novel to familiar place preference ratio	0.6	0.7	0.8	-0.9	-0.8	0.8
Novelty place preference	0.3	0.3	0.3	-0.6	-0.5	0.5
Time in novel zone, NPP test	0.1	0.1	0.2	-0.4	-0.4	0.4
Total zone transitions, NPP test	0.8	1.2	1.4	-0.9	-1.2	1.2
Total locomotion distance, NPP test	1.2	1.7	1.8	-1.2	-1.3	1.4
Locomotion velocity, NPP test	1.8	2.6	2.8	-1.5	-1.7	1.7
Pavlov. Cond. lever latency	2.3	3.0	3.2	1.6	1.8	-1.8
Pavlov. Cond. magazine entry latency	0.3	0.3	0.4	0.5	0.6	-0.6
Pavlov. Cond. change in total contacts	0.0	0.0	0.0	0.0	-0.1	0.1
Pavlov. Cond. index score	0.4	0.5	0.5	-0.6	-0.7	0.7
Pavlov. Cond. latency score	0.4	0.6	0.6	-0.6	-0.8	0.8
Pavlov. Cond. lever contacts	1.7	2.0	2.3	-1.1	-1.5	1.5
Pavlov. Cond. magazine entry number	0.2	0.3	0.3	-0.6	-0.5	0.5
Pavlov. Cond. intertrial magazine entries	0.2	0.3	0.3	-0.5	-0.6	0.5
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.5	0.6	-0.7	-0.8	0.8
Pavlov. Cond. response bias	0.1	0.2	0.2	-0.4	-0.4	0.4
Bone: apparent density	0.3	0.6	0.7	0.6	0.8	-0.8
Bone surface	0.2	0.3	0.4	0.3	0.6	-0.6
Bone volume	0.0	0.0	0.1	0.0	0.3	-0.2
Bone: connectivity density	0.7	1.2	1.5	0.8	1.2	-1.2
Bone: cortical apparent density	1.8	2.3	2.7	1.6	1.5	-1.5
Bone: cortical area	1.3	1.9	2.3	-1.5	-1.3	1.3
Bone: cortical porosity	0.1	0.1	0.4	0.7	0.1	-0.1
Bone: cortical porosity	0.5	0.5	1.1	1.0	0.5	-0.5
Bone: cortical thickness	2.6	4.3	4.6	-2.0	-2.1	2.1
Bone: cortical thickness	1.8	2.1	2.3	-1.4	-1.5	1.5
Bone: cortical tissue density	1.9	2.4	2.8	1.7	1.5	-1.5
Bone: elastic displacement	0.5	0.6	0.7	-0.8	-0.7	0.8
Bone: elastic work	0.7	0.9	1.2	-1.1	-0.8	0.8
Bone: endosteal estimation	0.1	0.1	0.2	-0.1	0.4	-0.4
Bone: endosteal perimeter	0.3	0.6	0.8	0.5	0.9	-0.9
Bone: final force	0.0	0.1	0.1	0.2	0.2	-0.3
Bone: final moment	0.0	0.0	0.0	-0.0	0.1	-0.1
Bone: marrow area	0.0	0.1	0.1	-0.2	0.3	-0.3
Bone: maximum diameter	0.0	0.1	0.1	-0.3	-0.3	0.3
Bone: maximum force	0.0	0.0	0.1	-0.3	-0.0	0.0
Bone: maximum moment	0.1	0.1	0.3	-0.6	-0.2	0.2
Bone: minimum diameter	0.5	0.9	1.9	-1.4	-0.7	0.7
Bone: periosteal estimation	0.3	0.7	1.1	-1.0	-0.7	0.7
Bone: periosteal perimeter	0.0	0.0	0.1	-0.3	-0.0	0.0
Bone: post-yield work	0.0	0.1	0.1	0.0	0.3	-0.3
Bone: stiffness	0.0	0.0	0.0	0.2	0.2	-0.2
Bone: tissue strength	0.4	0.4	0.5	0.2	0.7	-0.7
Bone: trabecular number	0.6	0.9	1.1	0.7	1.0	-1.0
Bone: trabecular spacing	0.8	1.1	1.4	-0.6	-1.2	1.2
Bone: trabecular thickness	0.7	0.8	1.0	0.6	1.0	-1.0
Bone: trabecular tissue density	0.2	0.3	0.6	0.8	0.4	-0.4
Breakpoint value in progressive ratio session	0.3	0.4	0.4	0.6	0.6	-0.6
Distance traveled before self-admin	0.5	0.5	0.6	-0.8	-0.7	0.7
Distance traveled after self-admin	3.9	4.3	4.6	-2.1	-2.0	2.0
Delta time in closed arm before/after self-admin	1.2	1.2	1.8	-1.3	-0.9	0.9
Delta time in open arm before/after self-admin	0.2	0.2	0.2	0.5	0.4	-0.4
Diff in mean of infusions in LGA sessions	0.0	0.0	0.1	0.1	0.2	-0.2
Extinction: sum of active levers before priming	0.0	0.0	0.1	0.3	0.0	-0.0
Active lever presses in extinction session 6	1.6	1.5	2.0	-1.4	-1.1	1.1
Delta distance traveled before/after self-admin	3.1	3.3	3.3	-1.8	-1.8	1.8
Delta ambulatory time before/after self-admin	2.1	2.2	2.3	-1.5	-1.5	1.5
Time in closed arm before self-admin	1.1	1.3	1.6	1.3	1.0	-1.0
Time in closed arm after self-admin	0.0	0.0	0.0	0.0	-0.1	0.1
Time in open arm before self-admin	0.0	0.0	0.1	-0.1	0.2	-0.2
Time in open arm after self-admin	0.0	0.0	0.1	-0.3	-0.1	0.1
Sum of active levers in priming session hrs 5-6	0.0	0.0	0.0	-0.1	-0.1	0.1
Time to tail flick, vehicle, before self-admin	0.8	0.8	1.0	-0.7	-1.0	1.0
Time to tail flick, vehicle, after self-admin	0.4	0.4	0.6	-0.3	-0.8	0.8
Time to tail flick, test, before self-admin	1.5	1.5	1.9	-0.8	-1.4	1.4
Time to tail flick, test, after self-admin	1.1	1.1	1.3	-0.9	-1.1	1.1
Delta time to tail flick, vehicle, before/after SA	0.0	0.0	0.1	-0.1	-0.2	0.2
Delta time to tail flick, test, before/after SA	0.2	0.2	0.3	0.3	0.5	-0.5
Ambulatory time before self-admin	0.7	0.7	0.9	-1.0	-0.8	0.8
Ambulatory time after self-admin	3.1	3.4	3.6	-1.9	-1.8	1.8
Total heroin consumption	3.0	3.6	3.9	2.0	1.9	-1.9
Area under the delay curve	0.3	0.3	0.3	0.6	0.5	-0.5
Delay disc. indifference point, 0s delay	1.2	1.3	1.3	1.1	1.1	-1.2
Delay disc. indifference point, 16s delay	1.0	1.0	1.1	-1.0	-1.0	1.0
Delay disc. indifference point, 2s delay	0.6	0.6	0.9	0.9	0.7	-0.7
Delay disc. indifference point, 24s delay	0.3	0.3	0.3	0.6	0.6	-0.6
Delay disc. indifference point, 4s delay	0.1	0.1	0.3	0.5	0.3	-0.3
Delay disc. indifference point, 8s delay	0.0	0.0	0.0	0.1	0.2	-0.2
Delay discount exponential model param	0.3	0.3	0.3	-0.6	-0.5	0.5
Delay discount hyperbolic model param	0.4	0.4	0.5	-0.7	-0.6	0.6
Fecal boli incidents, locomotor time 1	0.0	0.0	0.0	-0.2	0.1	-0.1
Change in fecal boli incidents, locomotor task	1.1	1.0	1.2	1.1	1.0	-1.0
Time >=10cm from walls, locomotor time 1	0.3	0.3	0.4	0.5	0.6	-0.6
Bouts of movement, locomotor time 1	1.2	1.4	1.4	1.2	1.2	-1.2
Total resting periods, locomotor time 1	1.0	1.1	1.2	1.1	1.0	-1.0
Rest time, locomotor task time 1	0.3	0.3	0.3	0.4	0.6	-0.6
Distance moved, locomotor task time 1	0.0	0.0	0.0	0.1	-0.1	0.1
Vertical activity count, locomotor time 1	0.3	0.4	0.4	-0.5	-0.6	0.6
Time >=10cm from walls, locomotor time 2	0.4	0.4	0.6	-0.8	-0.5	0.6
Bouts of movement, locomotor time 2	0.7	0.7	1.2	1.1	0.7	-0.7
Total resting periods, locomotor time 2	0.8	0.8	1.3	1.1	0.8	-0.8
Rest time, locomotor task time 2	0.6	0.7	1.0	1.0	0.8	-0.8
Distance moved, locomotor task time 2	1.9	2.2	2.8	-1.7	-1.4	1.4
Vertical activity count, locomotor time 2	3.0	3.2	4.2	-2.0	-1.7	1.7
Weight adjusted by age	0.2	0.2	0.3	-0.0	-0.6	0.6
Seeking ratio, delayed vs. immediate footshock	4.1	4.6	5.5	-2.4	-2.0	2.1
Locomotion in novel chamber	1.8	2.2	2.3	-1.5	-1.5	1.5
Locomotion in novel chamber post-restriction	0.4	0.5	0.6	-0.5	-0.8	0.8
Progressive ratio	0.0	0.0	0.1	0.1	-0.2	0.2
Food seeking constrained by brief footshock	2.3	2.8	3.2	1.4	1.8	-1.8
Seeking ratio, punishment vs. effort	1.6	2.0	2.4	1.1	1.6	-1.5
Run reversals in cocaine runway, females	0.9	0.9	1.2	1.1	0.9	-0.9
Run reversals in cocaine runway, males	2.1	2.0	2.5	-1.6	-1.4	1.3
Latency to leave start box in cocaine runway	1.4	1.6	1.7	-1.1	-1.3	1.3
Latency to leave start box in cocaine runway, F	1.9	2.1	2.4	-1.2	-1.5	1.5
Latency to leave start box in cocaine runway, M	0.0	0.0	0.1	-0.3	-0.1	0.1
Cd content in liver	0.1	0.1	0.2	0.2	0.4	-0.4
Co content in liver	0.2	0.2	0.4	0.2	0.6	-0.6
Cu content in liver	0.1	0.1	0.2	-0.2	0.4	-0.4
Fe content in liver	1.0	1.1	1.3	-0.9	-1.1	1.1
K content in liver	1.4	1.4	1.7	1.0	1.3	-1.3
Mg content in liver	0.1	0.1	0.1	0.1	0.3	-0.3
Mn content in liver	0.0	0.0	0.1	0.3	0.1	-0.1
Na content in liver	0.8	0.9	1.1	0.7	1.1	-1.1
Rb content in liver	0.1	0.1	0.1	0.3	0.3	-0.3
Se content in liver	0.1	0.1	0.1	-0.1	0.4	-0.4
Sr content in liver	0.0	0.0	0.1	-0.2	-0.1	0.2
Zn content in liver	0.5	0.5	0.7	0.5	0.8	-0.8