Hub : Genes

Pick1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000011507 0.03 0.02 9.1e-04 0.01 0.01 0.02 0.01 1.7e-02 9.0e-03 5.7e-03 8.5e-03
2 BLA gene expression ENSRNOG00000011507 0.08 0.04 2.8e-04 0.01 0.04 0.03 0.02 4.8e-02 2.3e-03 9.4e-03 1.8e-02
3 BLA intron excision ratio chr7:110797155:110797483 0.1 0.06 1.6e-03 0.06 0.03 0.06 0.05 5.6e-04 1.3e-02 6.6e-04 1.1e-03
4 Brain gene expression ENSRNOG00000011507 0.05 0.03 2.9e-04 0 0.04 0.03 0.03 3.2e-01 3.1e-04 8.6e-04 4.8e-04
5 Brain intron excision ratio chr7:110797155:110797483 0.09 0.04 2.4e-08 0.1 0.08 0.08 0.09 3.5e-09 1.6e-07 3.7e-08 1.0e-08
6 Brain intron excision ratio chr7:110797305:110797483 0.04 0.02 2.2e-03 0.03 0.01 0 0.01 6.2e-04 1.8e-02 1.6e-01 1.5e-02
7 Brain mRNA stability ENSRNOG00000011507 0.07 0.04 2.6e-05 0.05 0.04 0.03 0.04 3.1e-05 2.5e-04 1.3e-03 7.1e-05
8 LHb gene expression ENSRNOG00000011507 0.32 0.14 2.2e-03 0.11 0.07 0.14 0.16 1.3e-03 1.1e-02 2.7e-04 1.5e-04
9 NAcc intron excision ratio chr7:110797155:110797483 0.06 0.03 2.3e-04 0.06 0.05 0.05 0.04 6.0e-05 1.5e-04 1.6e-04 4.4e-04
10 NAcc intron excision ratio chr7:110797305:110797483 0.06 0.03 5.3e-04 0.03 0.04 0.05 0.04 2.3e-03 3.0e-04 7.8e-05 5.8e-04
11 OFC intron excision ratio chr7:110797155:110797483 0.17 0.1 9.9e-03 0.03 0.01 0.02 0.03 6.6e-02 2.3e-01 9.9e-02 7.7e-02
12 PL gene expression ENSRNOG00000011507 0.08 0.04 1.7e-06 0.09 0.06 0.08 0.09 1.2e-07 3.0e-05 6.6e-07 2.4e-07
13 PL intron excision ratio chr7:110797155:110797483 0.15 0.08 3.8e-07 0.09 0.08 0.08 0.09 1.2e-07 8.6e-07 1.2e-06 3.2e-07
14 PL mRNA stability ENSRNOG00000011507 0.06 0.03 7.9e-04 0 0.03 0.02 0.02 1.7e-01 3.2e-03 7.9e-03 1.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.10.21.40.1-0.6-0.0-0.40.30.2-1.2-0.8-0.0-0.40.3-0.10.00.1
BMI without tail0.51.11.9-1.1-1.2-1.4-0.8-1.01.2-1.00.1-1.10.8-1.1-1.3-1.10.2
Body weight0.93.99.22.02.02.11.52.1-2.1-0.2-1.41.9-2.63.02.22.0-0.1
Epididymis fat weight0.71.76.01.01.01.30.41.3-1.1-0.3-1.91.0-1.92.50.91.0-0.6
Glucose0.30.53.0-0.10.7-0.21.3-0.5-0.10.80.8-0.10.20.70.1-0.01.7
Heart weight2.02.86.41.42.41.32.50.7-1.81.60.61.6-1.42.41.51.61.5
Left kidney weight5.315.226.84.43.44.21.64.7-4.5-0.4-3.34.3-4.75.24.24.2-2.5
Right kidney weight5.616.138.94.24.24.42.74.2-4.41.0-3.04.3-4.36.24.44.2-1.5
Tail length0.20.51.80.01.30.11.4-0.5-0.21.30.80.1-0.20.80.30.11.0
Length with tail1.76.312.72.53.32.62.62.2-2.91.1-0.82.5-2.83.62.92.5-0.0
Length without tail3.16.814.52.72.83.01.82.8-3.00.9-1.72.7-2.93.83.02.7-0.7
Liver weight, left1.52.55.61.70.81.3-0.01.9-1.6-1.5-1.71.6-2.41.31.61.6-1.7
Liver weight, right1.52.55.41.81.51.70.71.7-1.60.2-1.31.7-2.32.01.81.7-0.8
Parametrial fat weight0.71.35.6-0.01.30.12.1-0.7-0.21.61.90.20.20.10.20.22.4
Retroperitoneal fat weight2.27.315.12.92.92.82.32.6-2.90.2-1.63.0-3.53.93.03.0-0.1
Intraocular pressure0.40.61.40.80.30.7-0.21.0-0.6-0.6-1.00.8-0.80.50.70.8-1.2
Extensor digitorum longus weight0.72.85.5-1.8-2.3-1.9-1.5-1.51.9-1.00.4-1.91.6-2.1-1.8-1.80.9
Soleus weight1.13.19.4-1.30.6-1.51.9-2.21.12.13.0-1.02.0-0.5-1.0-1.03.1
Tibialis anterior weight2.58.812.5-3.5-3.4-3.4-2.2-3.13.4-0.31.1-3.53.5-3.1-3.4-3.41.3
Tibia length0.51.42.41.51.01.00.71.5-1.5-1.0-0.71.5-1.40.81.11.4-0.7
Number of licking bursts0.70.81.8-0.9-0.4-1.2-0.0-1.21.0-0.11.3-0.91.0-1.2-0.9-0.90.5
Food consumed during 24 hour testing period0.20.21.10.1-0.3-0.1-0.40.3-0.0-1.0-0.80.0-0.30.60.10.0-0.9
Times rat made contact with spout1.51.76.3-1.10.7-1.31.4-1.81.01.32.5-0.81.3-0.5-1.1-0.81.6
Mean time between licks in bursts0.30.52.60.3-1.00.1-1.00.5-0.1-1.6-0.5-0.0-0.3-0.90.0-0.0-0.7
Mean num. licks in bursts0.20.31.10.10.80.20.8-0.1-0.21.10.20.2-0.20.90.10.20.4
Std. dev. time between licks in bursts0.30.40.90.90.60.70.40.9-1.00.10.00.8-0.50.20.70.8-0.3
Water consumed over 24 hours0.20.20.6-0.30.3-0.70.4-0.70.40.50.8-0.30.40.3-0.4-0.30.2
Indifference point 0 sec0.40.61.70.41.20.61.3-0.2-0.31.30.80.6-0.21.10.60.60.8
Indifference point AUC0.91.12.2-1.3-0.9-1.2-0.8-1.11.10.10.4-1.31.5-0.7-1.2-1.3-0.6
Indifference point function ln k1.31.84.11.61.11.60.81.4-1.3-0.3-1.01.6-2.01.51.41.5-0.1
Indifference point function log k1.31.84.11.61.11.60.81.4-1.3-0.3-1.01.6-2.01.51.41.5-0.1
Delay discounting total patch changes 0 sec0.20.41.4-0.10.60.10.9-0.70.21.20.80.10.30.60.00.00.9
Delay discounting total patch changes 12 sec0.10.10.60.00.2-0.0-0.0-0.10.10.0-0.40.20.20.6-0.10.1-0.8
Delay discounting total patch changes 18 sec0.10.20.4-0.20.4-0.20.6-0.60.30.50.6-0.10.70.4-0.0-0.10.1
Delay discounting total patch changes 24 sec0.91.12.5-1.1-0.1-1.30.4-1.61.01.21.4-0.91.3-0.2-1.1-0.91.0
Delay discounting total patch changes 6 sec0.10.20.6-0.50.1-0.40.2-0.70.40.50.6-0.40.80.2-0.2-0.40.1
Delay discounting time to switch 0 sec0.50.72.40.6-0.90.3-1.11.0-0.2-1.5-1.60.4-0.50.00.50.5-0.9
Delay discounting water rate 0 sec1.32.06.60.52.20.72.6-0.3-1.02.32.00.8-0.21.00.70.81.8
Delay discounting water rate 12 sec0.40.62.2-0.10.9-0.51.4-0.7-0.10.41.30.1-0.30.2-0.2-0.01.5
Delay discounting water rate 18 sec1.01.44.50.72.00.52.10.0-1.11.11.81.1-0.40.50.91.00.9
Delay discounting water rate 24 sec1.82.55.21.62.31.52.01.2-1.80.90.11.7-1.81.91.61.70.5
Delay discounting water rate 6 sec1.01.55.1-0.41.2-0.52.0-1.30.31.62.3-0.20.3-0.3-0.3-0.32.2
Locomotor activity0.50.82.00.90.80.80.50.7-0.7-0.2-1.20.9-1.41.40.60.8-0.4
Locomotor testing distance0.60.92.3-1.1-0.5-1.2-0.1-1.51.30.40.3-1.00.6-0.3-1.4-1.10.9
Locomotor testing rearing0.10.21.20.30.10.1-0.20.2-0.0-0.3-1.10.3-0.60.6-0.10.3-0.8
Light reinforcement 10.10.10.70.3-0.00.2-0.20.4-0.2-0.8-0.30.3-0.50.20.30.3-0.6
Light reinforcement 20.20.31.50.1-0.40.1-0.70.40.0-1.2-1.0-0.0-0.70.40.10.0-0.7
Reaction time number correct0.60.92.6-1.0-0.8-1.3-0.8-0.91.0-0.40.8-0.90.6-1.6-1.0-0.9-0.4
Reaction time mean minus median0.00.00.20.20.10.4-0.10.3-0.20.2-0.30.1-0.10.20.30.1-0.1
Reaction time mean minus median AUC0.10.10.30.20.30.50.20.2-0.30.6-0.40.2-0.20.60.30.10.2
Reaction time num false alarms0.10.10.5-0.2-0.1-0.3-0.0-0.40.30.3-0.3-0.20.00.7-0.4-0.20.1
Reaction time num false alarms AUC0.10.10.4-0.3-0.2-0.4-0.3-0.40.40.3-0.4-0.30.20.6-0.6-0.3-0.1
Reaction time trials correct on left0.60.92.6-1.0-0.8-1.3-0.8-0.91.0-0.40.8-0.90.6-1.6-1.0-0.9-0.4
Reaction time trials on left0.81.12.9-1.1-0.9-1.4-0.9-1.01.1-0.50.8-1.00.7-1.7-1.1-1.1-0.4
Reaction time mean0.40.51.20.70.71.10.70.6-0.90.50.20.7-0.50.71.00.60.6
Reaction time mean AUC0.20.30.70.40.50.90.50.4-0.60.40.10.4-0.30.60.80.40.4
Median of all reaction times0.30.51.10.70.61.10.70.6-0.90.30.20.6-0.40.61.00.60.6
Reaction time omissions2.43.27.0-1.7-2.6-1.7-2.6-0.91.8-2.1-1.1-1.91.3-1.7-1.7-1.8-1.2
Reaction time false alarm rate0.10.11.20.00.00.20.1-0.10.10.6-0.6-0.00.01.1-0.2-0.00.3
Reaction time premature initiation rate0.20.20.70.50.40.30.40.4-0.3-0.4-0.40.5-0.40.80.50.5-0.1
Reaction time premature initiations0.00.00.1-0.00.1-0.20.0-0.10.2-0.30.00.0-0.00.2-0.0-0.0-0.2
Std. dev. reaction times0.20.31.00.50.60.90.40.5-0.60.5-0.40.4-0.51.00.70.40.1
Reaction time trials completed0.81.12.9-1.1-0.9-1.4-0.9-1.01.1-0.50.8-1.00.7-1.7-1.1-1.1-0.4
Reaction time trials AUC0.50.72.0-0.9-0.7-1.2-0.8-0.80.9-0.40.6-0.80.5-1.4-0.9-0.9-0.5
Social response proportion1.51.65.40.7-1.10.7-1.51.6-0.6-2.3-2.20.6-1.10.40.70.6-1.7
Social responses0.40.51.7-0.3-1.0-0.3-1.20.10.5-1.3-0.9-0.30.2-0.5-0.3-0.3-1.1
Social time1.41.83.1-1.5-1.6-1.6-1.1-1.21.4-0.80.4-1.41.7-1.8-1.5-1.50.1
Conditioned locomotion1.11.32.01.31.41.11.31.1-1.4-0.30.11.4-1.41.01.41.40.1
Cocaine response after cond. corrected0.70.72.30.80.10.8-0.21.1-0.8-1.5-1.20.7-0.90.40.70.7-1.0
Cocaine response after cond. not corrected0.40.42.30.4-0.30.3-0.40.7-0.4-1.5-1.10.3-0.60.30.20.3-0.7
Cocaine response before conditioning0.91.12.0-1.3-0.8-1.4-0.4-1.31.20.30.6-1.21.0-0.8-1.2-1.20.7
Saline control response0.20.30.80.40.50.80.20.3-0.40.9-0.30.4-0.70.70.20.4-0.1
Condit. Reinf. active minus inactive responses0.20.20.9-0.3-0.8-0.3-0.9-0.00.4-0.0-0.6-0.40.6-0.2-0.3-0.4-0.7
Condit. Reinf. active-inactive response ratio0.10.10.70.3-0.10.2-0.30.5-0.30.0-0.90.2-0.00.20.20.2-0.6
Condit. Reinf. active responses0.40.52.4-0.0-0.9-0.1-1.40.40.2-0.5-1.3-0.20.10.10.0-0.2-1.5
Condit. Reinf. inactive responses0.30.31.6-0.3-0.6-0.5-1.0-0.10.4-0.9-0.4-0.30.1-0.2-0.1-0.3-1.3
Condit. Reinf. lever presses0.40.61.0-0.8-0.6-0.9-0.3-0.90.90.80.7-0.81.0-0.7-0.6-0.80.6
Condit. Reinf. lever reinforcers received0.30.41.90.2-0.60.1-1.10.5-0.0-0.3-1.30.1-0.10.30.30.1-1.4
Pavlov. Cond. lever latency0.30.50.8-0.7-0.8-0.6-0.9-0.40.6-0.8-0.6-0.70.4-0.3-0.8-0.7-0.8
Pavlov. Cond. magazine entry latency0.50.61.4-0.7-0.6-0.8-0.1-1.00.90.90.7-0.71.2-0.6-0.8-0.70.9
Pavlov. Cond. change in total contacts2.23.15.12.21.92.01.71.9-2.20.4-0.12.2-1.51.52.22.20.1
Pavlov. Cond. index score0.20.31.40.30.40.10.7-0.1-0.11.20.90.30.30.00.20.31.0
Pavlov. Cond. latency score0.40.41.90.20.50.10.9-0.2-0.11.41.10.20.5-0.00.20.21.2
Pavlov. Cond. lever contacts0.30.41.10.50.80.41.00.1-0.41.01.00.5-0.20.30.60.51.0
Pavlov. Cond. magazine entry number0.20.31.8-0.1-0.2-0.0-0.50.2-0.0-1.3-0.7-0.1-0.5-0.1-0.1-0.1-0.8
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.20.40.10.6-0.3-0.00.50.4-0.10.40.1-0.1-0.10.5
Pavlov. Cond. lever-magazine prob. diff.0.20.21.10.30.30.10.6-0.1-0.11.00.80.30.3-0.00.20.30.9
Pavlov. Cond. response bias0.10.20.30.50.30.20.50.2-0.30.50.60.4-0.10.10.60.40.6
Conditioned reinforcement - actives1.81.83.2-1.6-1.7-1.3-1.8-0.91.3-0.6-0.5-1.71.4-1.0-1.3-1.7-1.1
Conditioned reinforcement - inactives2.12.44.7-2.0-1.1-1.7-0.5-2.01.50.81.0-2.02.2-1.2-1.7-1.90.9
Conditioned locomotion1.11.33.3-1.2-1.5-0.7-1.8-0.10.7-0.9-1.6-1.40.70.2-0.7-1.3-1.4
Intermittent access intake day 1-15 change0.60.61.4-0.8-0.4-1.0-0.0-1.20.80.50.7-0.80.7-0.3-1.0-0.80.5
Intermittent access intake escalation1.01.02.2-1.1-0.7-1.4-0.2-1.51.20.30.7-1.11.0-0.6-1.4-1.10.7
Intermittent access intake escalation 20.70.71.7-0.8-0.3-1.00.2-1.30.80.70.9-0.80.8-0.4-1.0-0.81.0
Intermitt. access day 1 inactive lever presses0.60.71.30.91.01.00.90.8-1.10.4-0.01.0-0.40.81.01.0-0.0
Intermitt. access day 15 inactive lever presses0.10.20.70.30.50.30.6-0.1-0.30.40.20.4-0.10.80.30.30.2
Intermitt. access escalation Index0.60.61.1-0.9-0.8-0.9-0.7-0.71.0-0.40.3-0.80.7-0.9-0.9-0.8-0.0
Intermittent access day 1 total infusions1.11.25.3-0.5-1.1-0.2-1.80.60.0-1.3-1.8-0.7-0.00.6-0.2-0.7-2.3
Intermittent access day 15 total infusions0.60.71.3-0.8-1.0-0.9-1.1-0.40.6-0.6-0.7-1.00.60.3-0.9-1.0-1.1
Intermittent access terminal intake (last 3 days)0.50.51.6-0.7-0.8-0.7-1.1-0.20.4-0.5-0.6-0.80.40.2-0.7-0.8-1.2
Intermittent access total infusions1.01.13.5-0.7-1.4-0.7-1.80.20.5-1.3-1.4-0.90.40.2-0.7-0.9-1.9
Intermittent access day 1 locomotion0.30.31.0-0.4-0.5-0.2-0.80.2-0.1-0.4-1.0-0.50.10.7-0.2-0.5-1.0
Intermittent access day 15 total locomotion0.20.30.6-0.7-0.3-0.6-0.3-0.50.30.2-0.2-0.80.30.7-0.6-0.8-0.1
Intermittent access total locomotion0.20.22.1-0.5-0.1-0.2-0.1-0.2-0.10.3-0.7-0.50.11.4-0.2-0.5-0.1
Intermittent access standard deviation0.40.41.5-0.4-0.6-0.6-0.6-0.30.5-0.4-1.0-0.60.21.2-0.6-0.6-0.6
Cocaine induced anxiety0.30.41.00.70.20.80.00.9-0.6-0.2-0.70.5-1.00.40.80.50.0
Post-drug Anxiety4.14.57.42.62.42.72.02.2-2.50.9-0.12.5-2.21.52.72.50.5
Baseline Anxiety1.41.54.30.81.80.92.1-0.0-1.01.71.81.0-0.10.10.91.01.6
Lifetime Intake1.01.13.7-0.6-1.3-0.6-1.70.30.4-1.4-1.6-0.80.30.4-0.6-0.8-1.9
Incentive Sensitization - Responses0.70.71.5-1.0-0.2-0.90.0-1.20.60.81.0-0.91.0-0.7-0.9-0.90.6
Incentive Sensitization - Breakpoint0.70.71.5-1.1-0.3-0.9-0.0-1.20.60.81.0-1.01.1-0.7-0.9-1.00.6
Progressive ratio test 1 active lever presses0.60.61.5-0.8-1.1-0.6-1.2-0.20.5-0.6-0.6-0.90.8-0.2-0.6-1.0-1.0
Progressive ratio test 1 breakpoint0.30.30.7-0.6-0.6-0.4-0.8-0.20.3-0.3-0.3-0.70.6-0.1-0.4-0.7-0.8
Progressive ratio test 1 inactive lever presses0.90.92.5-1.1-1.6-0.8-1.3-0.40.8-0.6-0.4-1.31.0-0.8-0.8-1.3-0.1
Progressive ratio test 2 active lever presses1.21.32.4-1.5-1.0-1.3-0.7-1.41.10.30.5-1.51.5-0.7-1.3-1.5-0.1
Progressive ratio test 2 breakpoint0.60.61.3-1.1-0.7-0.9-0.6-0.80.70.10.2-1.01.1-0.5-0.9-1.1-0.4
Progressive ratio test 2 inactive lever presses1.61.83.0-1.6-1.4-1.6-1.1-1.51.4-0.00.6-1.71.7-1.2-1.6-1.7-0.1
Total sessions with >9 infusions0.20.21.1-0.2-0.10.1-0.50.3-0.2-0.3-0.9-0.20.10.80.1-0.2-1.0
Short access day 1 total inactive lever presses0.70.71.60.60.31.1-0.21.2-1.0-0.2-1.10.6-0.41.31.10.6-1.2
Short access day 10 total inactive lever presses2.32.56.11.52.51.62.40.6-1.61.70.81.6-1.21.71.61.60.9
Short access day 1 total infusions0.20.20.80.30.20.5-0.10.5-0.5-0.1-0.60.3-0.20.90.50.2-0.8
Short access day 10 total infusions1.11.25.0-0.1-0.9-0.1-1.60.80.0-1.5-2.0-0.3-0.30.9-0.1-0.4-2.2
Short access total infusions0.80.94.00.3-0.40.4-1.01.1-0.5-1.2-1.80.2-0.51.10.40.2-2.0
Short access day 1 locomotion0.40.41.2-0.6-0.7-0.2-1.00.00.4-0.4-0.9-0.70.50.3-0.2-0.7-1.1
Short access day 10 total locomotion1.11.22.0-1.4-0.6-1.20.2-1.40.90.90.5-1.31.40.3-1.2-1.31.4
Short access total locomotion0.20.21.6-0.2-0.00.1-0.10.1-0.30.3-0.7-0.30.21.30.1-0.3-0.3
Compulsive drug intake2.92.85.5-1.7-0.4-1.50.6-2.21.51.52.2-1.62.1-1.6-1.5-1.62.3
One hour access (0.3 mA shock)4.04.76.8-2.5-2.6-2.6-2.3-1.82.4-1.10.0-2.62.3-1.9-2.6-2.6-0.7
One hour access (shock baseline)0.91.12.8-1.0-1.5-1.0-1.7-0.20.8-1.2-1.0-1.10.4-0.2-1.0-1.1-1.3
Number of responses in last shaping day3.53.68.0-1.8-2.8-1.8-2.8-0.41.6-2.1-1.2-2.01.6-1.6-1.8-2.0-1.7
Context. condit. distance diff. score2.32.85.61.71.82.31.21.6-1.71.4-1.11.7-2.22.41.61.7-0.1
Locomotion velocity, session 11.41.54.21.40.60.9-0.31.6-1.3-0.7-1.21.3-1.20.81.41.3-2.0
Locomotion distance, session 11.92.45.3-1.3-1.9-1.7-2.1-0.91.5-1.60.1-1.41.5-2.3-1.2-1.4-1.8
Locomotion velocity, session 21.01.24.30.5-0.7-0.0-1.41.0-0.4-2.1-1.80.4-0.90.30.50.4-2.1
Locomotion distance, session 22.23.15.4-1.7-2.2-1.9-2.3-1.21.8-1.5-0.2-1.82.0-2.0-1.6-1.8-1.6
Locomotion velocity, session 30.80.91.70.91.01.30.11.0-0.90.4-0.50.8-1.21.01.10.9-1.3
Locomotion distance, session 31.01.11.9-1.2-0.5-1.1-0.4-1.31.10.51.3-1.21.0-1.4-1.3-1.10.1
Stereotopy head waving bouts, day 30.91.11.81.20.91.10.51.3-1.3-0.2-0.91.2-1.01.11.31.2-0.5
Stereotopy head waving duration, day 34.45.38.82.72.12.51.32.8-2.7-0.6-1.52.7-2.72.43.02.6-1.0
Locomotion velocity, session 70.91.01.71.21.31.11.30.8-1.20.00.51.2-1.00.61.01.20.4
Locomotion distance, session 70.60.81.60.81.31.11.30.4-0.91.20.90.8-0.10.50.70.80.6
Stereotopy head waving bouts, day 75.05.710.62.81.82.30.73.0-2.7-1.1-1.82.7-3.32.22.82.8-1.7
Stereotopy head waving duration, day 72.93.67.72.21.21.80.22.5-2.1-1.1-1.62.2-2.81.62.22.2-1.4
Locomotion velocity, session 82.83.35.52.01.21.9-0.02.3-1.9-0.6-1.91.9-2.11.92.01.9-2.1
Locomotion distance, session 80.40.61.30.70.31.1-0.31.0-0.70.1-1.00.7-1.00.70.70.7-1.0
Degree of sensitization distance4.04.06.72.42.12.61.92.1-2.41.1-0.62.3-1.52.32.32.30.5
Degree of sensitization stereotypy3.74.08.22.31.11.8-0.12.6-2.2-1.4-1.82.2-2.91.52.22.2-2.1
Condit. Reinf. active minus inactive responses0.40.51.7-0.50.4-0.60.6-0.80.41.31.0-0.40.7-0.2-0.7-0.40.8
Condit. Reinf. active-inactive response ratio0.20.21.7-0.00.7-0.10.6-0.3-0.01.30.60.00.10.4-0.3-0.00.4
Condit. Reinf. active responses1.51.85.2-1.20.2-0.90.8-1.61.02.31.9-1.01.5-0.8-1.2-1.01.9
Condit. Reinf. inactive responses2.12.55.8-1.6-0.2-0.80.6-2.01.42.42.1-1.41.9-1.2-1.1-1.42.4
Incentive salience index mean0.91.13.5-0.60.7-0.71.3-1.10.41.51.9-0.40.9-0.3-0.6-0.41.7
Condit. Reinf. lever presses1.21.65.9-0.70.7-0.81.7-1.50.61.32.4-0.61.0-0.3-0.6-0.62.4
Time in familiar zone, hab. session 10.40.40.90.80.50.20.50.7-0.8-0.90.40.8-0.6-0.30.70.8-0.4
Time in novel zone, hab. session 10.30.31.20.30.20.8-0.10.4-0.20.0-1.10.3-0.81.10.40.3-0.4
Total zone transitions, hab. session 11.62.33.5-1.9-1.5-1.7-1.3-1.71.80.00.9-1.81.5-1.8-1.7-1.80.0
Total locomotion distance, hab. session 10.60.91.6-1.3-0.7-1.2-0.7-1.21.20.30.6-1.20.7-0.8-1.2-1.20.1
Locomotion velocity, hab. session 10.91.22.1-1.5-0.8-1.3-0.7-1.41.40.40.8-1.41.1-0.9-1.3-1.40.3
Time in familiar zone, hab. session 20.20.21.3-0.30.1-0.60.4-0.40.2-0.11.2-0.2-0.0-0.7-0.2-0.20.5
Time in novel zone, hab. session 20.30.31.3-0.4-0.6-0.1-0.7-0.30.50.4-1.1-0.50.50.6-0.5-0.5-0.3
Total zone transitions, hab. session 20.30.40.9-0.8-0.3-0.8-0.3-0.80.7-0.20.9-0.71.0-0.8-0.3-0.7-0.4
Total locomotion distance, hab. session 20.20.20.8-0.4-0.6-0.6-0.7-0.10.4-0.7-0.1-0.40.4-0.3-0.2-0.4-0.9
Locomotion velocity, hab. session 20.10.20.4-0.4-0.4-0.6-0.4-0.20.3-0.50.3-0.40.5-0.4-0.2-0.3-0.6
Novel to familiar place preference ratio0.90.92.21.00.70.9-0.01.1-0.90.3-1.30.9-1.41.50.70.9-0.9
Novelty place preference0.90.92.60.90.80.90.11.0-0.80.3-1.30.8-1.51.60.70.9-0.8
Time in novel zone, NPP test0.91.03.00.90.81.00.11.0-0.80.5-1.30.8-1.51.70.70.8-0.8
Total zone transitions, NPP test1.21.73.3-1.5-1.1-1.6-1.0-1.41.5-0.11.1-1.41.5-1.8-1.3-1.4-0.3
Total locomotion distance, NPP test0.10.10.8-0.2-0.3-0.3-0.60.00.2-0.10.2-0.20.3-0.6-0.2-0.2-0.9
Locomotion velocity, NPP test0.30.41.2-0.5-0.6-0.7-0.7-0.40.5-0.30.5-0.50.6-1.1-0.5-0.5-0.7
Pavlov. Cond. lever latency0.20.20.70.20.00.7-0.30.5-0.3-0.1-0.80.2-0.40.40.40.2-0.6
Pavlov. Cond. magazine entry latency0.81.02.0-0.9-1.3-1.4-0.8-0.81.0-1.30.3-1.01.0-1.0-1.0-1.00.0
Pavlov. Cond. change in total contacts1.11.12.4-1.1-1.3-1.5-0.9-1.01.1-0.90.4-1.11.4-1.0-1.3-1.1-0.2
Pavlov. Cond. index score0.10.10.6-0.2-0.3-0.80.1-0.30.2-0.60.5-0.20.5-0.2-0.4-0.20.2
Pavlov. Cond. latency score0.10.10.4-0.1-0.2-0.60.1-0.20.2-0.40.4-0.10.3-0.1-0.3-0.10.2
Pavlov. Cond. lever contacts0.20.20.9-0.2-0.0-0.70.4-0.50.3-0.01.0-0.20.6-0.5-0.5-0.20.7
Pavlov. Cond. magazine entry number0.50.61.50.70.91.20.50.8-0.80.9-0.50.8-0.90.80.80.80.0
Pavlov. Cond. intertrial magazine entries0.60.73.7-0.30.80.31.1-0.70.11.91.3-0.10.8-0.3-0.2-0.11.2
Pavlov. Cond. lever-magazine prob. diff.0.20.30.8-0.4-0.4-0.9-0.0-0.60.5-0.60.7-0.50.7-0.5-0.6-0.40.3
Pavlov. Cond. response bias0.40.51.3-0.5-0.6-1.1-0.0-0.70.6-0.60.8-0.60.9-0.7-0.7-0.60.4
Bone: apparent density0.00.00.3-0.1-0.1-0.00.1-0.20.10.20.2-0.10.20.0-0.1-0.10.5
Bone surface0.10.21.00.2-0.2-0.0-0.50.3-0.1-1.0-0.40.2-0.20.10.10.2-0.9
Bone volume0.00.00.1-0.3-0.2-0.3-0.1-0.20.2-0.30.1-0.20.20.0-0.2-0.20.0
Bone: connectivity density0.20.30.60.60.70.80.60.3-0.50.50.20.6-0.30.50.50.60.2
Bone: cortical apparent density0.60.83.1-0.70.4-0.50.9-1.10.51.01.7-0.60.5-0.8-0.6-0.61.4
Bone: cortical area0.20.31.20.60.2-0.10.40.6-0.6-1.1-0.50.6-0.60.90.30.6-0.2
Bone: cortical porosity1.11.22.81.10.10.9-0.31.3-0.9-1.3-1.71.0-1.31.30.90.9-1.2
Bone: cortical porosity1.82.05.21.30.10.9-0.61.7-1.1-1.7-2.31.2-1.61.61.11.1-1.9
Bone: cortical thickness1.21.93.7-1.6-1.3-1.9-0.6-1.71.6-0.40.5-1.61.6-0.8-1.9-1.60.8
Bone: cortical thickness1.72.04.2-1.6-1.5-2.0-0.8-1.51.6-0.50.5-1.51.6-1.4-1.8-1.50.5
Bone: cortical tissue density0.50.72.9-0.60.5-0.41.0-0.90.41.01.7-0.50.5-0.7-0.5-0.51.4
Bone: elastic displacement1.11.22.31.31.01.30.71.3-1.3-0.1-0.31.3-1.21.11.51.3-0.3
Bone: elastic work3.14.06.62.41.21.70.62.6-2.4-1.2-2.02.4-2.32.22.02.4-1.3
Bone: endosteal estimation2.24.87.52.51.62.00.62.7-2.5-1.3-1.82.4-2.62.42.62.4-1.9
Bone: endosteal perimeter2.55.18.42.51.62.00.82.8-2.6-2.0-1.72.6-2.92.22.62.6-1.7
Bone: final force0.71.12.41.30.30.40.11.3-1.2-1.5-1.31.2-1.10.90.71.1-1.0
Bone: final moment0.91.52.41.50.60.70.31.5-1.4-1.4-1.31.4-1.31.21.01.4-1.0
Bone: marrow area2.45.28.22.61.62.10.62.9-2.6-1.4-1.92.5-2.72.52.72.5-2.0
Bone: maximum diameter2.54.57.32.41.61.60.92.5-2.4-1.7-1.82.4-2.62.72.42.4-1.4
Bone: maximum force0.91.62.81.50.40.70.11.6-1.4-1.7-1.51.4-1.31.21.01.3-1.3
Bone: maximum moment1.22.03.41.70.61.00.21.8-1.6-1.6-1.61.6-1.41.51.21.6-1.4
Bone: minimum diameter0.30.51.30.70.20.4-0.10.9-0.7-0.7-1.10.7-0.71.10.60.7-0.9
Bone: periosteal estimation1.53.14.82.01.11.30.52.2-2.0-1.6-1.62.0-2.12.01.91.9-1.5
Bone: periosteal perimeter2.84.77.22.51.81.81.12.6-2.5-1.8-1.52.5-2.72.42.42.5-1.4
Bone: post-yield work0.20.32.40.4-0.20.0-0.20.5-0.4-1.5-0.20.4-0.3-0.50.30.3-0.9
Bone: stiffness0.91.42.41.50.90.90.91.4-1.4-1.0-0.81.4-1.31.41.11.4-0.3
Bone: tissue strength0.30.30.90.60.30.60.20.5-0.5-0.1-0.60.5-0.60.90.40.50.0
Bone: trabecular number0.10.10.30.40.40.50.40.2-0.40.20.20.3-0.40.30.30.30.3
Bone: trabecular spacing0.40.50.90.80.70.60.80.6-0.8-1.00.10.8-0.60.50.80.8-0.2
Bone: trabecular thickness0.20.31.4-0.40.0-0.20.3-0.50.31.20.6-0.40.6-0.0-0.4-0.41.0
Bone: trabecular tissue density0.40.62.8-0.10.5-0.01.1-0.50.11.21.3-0.10.6-0.3-0.1-0.11.7
Breakpoint value in progressive ratio session1.01.11.8-1.1-1.1-1.3-0.5-1.21.10.10.4-1.11.2-1.1-1.3-1.10.9
Distance traveled before self-admin1.21.33.8-0.9-1.9-1.2-1.8-0.61.2-1.0-0.8-1.00.9-0.8-1.2-1.3-0.7
Distance traveled after self-admin0.40.40.80.70.80.90.70.5-0.80.40.10.70.00.70.90.7-0.4
Delta time in closed arm before/after self-admin0.30.30.5-0.6-0.6-0.6-0.6-0.50.6-0.2-0.6-0.70.40.3-0.6-0.7-0.3
Delta time in open arm before/after self-admin0.10.10.2-0.3-0.4-0.2-0.4-0.10.3-0.3-0.0-0.20.4-0.5-0.3-0.1-0.2
Diff in mean of infusions in LGA sessions0.40.41.3-0.8-0.0-0.50.1-0.70.40.60.9-0.71.1-0.8-0.5-0.70.3
Extinction: sum of active levers before priming2.02.14.1-1.2-2.0-1.5-1.8-0.91.5-1.4-0.2-1.41.5-2.0-1.6-1.2-0.7
Active lever presses in extinction session 60.00.00.10.3-0.00.1-0.00.2-0.1-0.2-0.10.30.0-0.10.00.2-0.2
Delta distance traveled before/after self-admin3.33.58.51.82.92.22.41.3-2.11.30.62.0-1.31.72.22.10.0
Delta ambulatory time before/after self-admin3.74.08.92.13.02.42.31.7-2.41.00.32.2-1.61.62.42.5-0.5
Time in closed arm before self-admin0.60.61.7-0.7-0.8-0.90.0-1.00.90.30.7-0.71.0-0.6-0.8-0.71.3
Time in closed arm after self-admin0.40.41.20.10.60.30.9-0.3-0.21.10.20.10.11.10.30.11.0
Time in open arm before self-admin0.50.61.40.71.20.81.00.5-0.90.70.70.8-0.60.10.80.60.2
Time in open arm after self-admin0.20.30.7-0.5-0.1-0.50.1-0.70.50.30.8-0.30.4-0.8-0.5-0.30.6
Sum of active levers in priming session hrs 5-60.10.10.2-0.2-0.5-0.2-0.3-0.00.1-0.30.0-0.20.5-0.5-0.2-0.10.3
Time to tail flick, vehicle, before self-admin0.10.10.2-0.3-0.2-0.0-0.4-0.10.20.1-0.3-0.40.10.3-0.1-0.4-0.2
Time to tail flick, vehicle, after self-admin0.30.30.9-0.10.90.51.0-0.1-0.40.90.70.20.10.20.50.10.7
Time to tail flick, test, before self-admin1.61.52.3-1.4-1.4-1.5-1.4-1.01.4-0.6-0.1-1.31.3-1.4-1.4-1.4-0.5
Time to tail flick, test, after self-admin0.40.51.9-0.50.1-0.40.4-0.80.20.41.4-0.20.8-1.3-0.3-0.40.7
Delta time to tail flick, vehicle, before/after SA0.10.10.10.20.30.30.30.3-0.30.00.10.30.1-0.00.20.4-0.1
Delta time to tail flick, test, before/after SA0.70.62.6-0.30.5-0.21.0-0.90.21.01.6-0.20.3-0.6-0.1-0.31.6
Ambulatory time before self-admin1.81.93.4-1.6-1.8-1.5-1.4-1.41.5-0.4-0.0-1.61.5-1.1-1.5-1.80.2
Ambulatory time after self-admin0.20.20.60.30.80.50.80.1-0.60.60.50.40.20.30.50.5-0.1
Total heroin consumption1.11.32.7-1.0-1.6-1.5-1.6-0.81.3-1.2-0.7-1.00.7-1.0-1.5-0.9-1.0
Area under the delay curve2.52.75.4-1.6-2.2-1.7-2.0-1.21.8-0.70.1-1.62.1-2.3-1.7-1.6-0.5
Delay disc. indifference point, 0s delay0.20.30.8-0.3-0.9-0.6-0.5-0.40.7-0.3-0.6-0.40.30.3-0.5-0.50.5
Delay disc. indifference point, 16s delay2.52.55.5-1.7-2.1-1.5-1.9-1.11.7-1.00.2-1.71.9-2.3-1.5-1.6-0.6
Delay disc. indifference point, 2s delay5.96.615.4-2.2-3.9-2.6-3.7-1.42.8-2.5-1.2-2.52.2-2.7-2.6-2.6-1.4
Delay disc. indifference point, 24s delay0.40.41.10.30.90.70.70.2-0.60.21.00.50.2-0.60.70.7-0.7
Delay disc. indifference point, 4s delay1.11.23.1-0.8-1.8-1.0-1.8-0.31.0-1.0-0.6-0.81.2-1.4-1.0-0.8-0.8
Delay disc. indifference point, 8s delay2.12.14.6-1.6-1.3-1.6-0.7-1.71.60.51.2-1.42.2-2.1-1.5-1.30.7
Delay discount exponential model param2.62.85.61.72.21.72.01.3-1.80.7-0.21.7-2.12.41.71.60.5
Delay discount hyperbolic model param3.13.36.41.72.51.92.31.3-2.01.00.11.8-2.12.41.91.80.6
Fecal boli incidents, locomotor time 10.30.41.00.50.90.41.00.4-0.80.80.70.50.40.20.50.5-0.1
Change in fecal boli incidents, locomotor task0.20.20.40.30.60.40.5-0.1-0.10.60.10.4-0.50.40.40.3-0.1
Time >=10cm from walls, locomotor time 10.80.81.60.90.71.10.41.0-1.0-0.1-0.70.8-0.81.31.01.0-0.6
Bouts of movement, locomotor time 10.10.10.40.30.40.00.40.2-0.3-0.4-0.10.5-0.50.60.10.4-0.1
Total resting periods, locomotor time 10.20.20.50.50.50.30.60.4-0.6-0.40.10.7-0.50.50.40.60.0
Rest time, locomotor task time 10.60.71.70.71.20.81.30.4-0.91.20.80.90.10.40.90.90.5
Distance moved, locomotor task time 10.20.30.80.40.20.6-0.20.7-0.5-0.5-0.70.3-0.90.30.40.3-0.6
Vertical activity count, locomotor time 10.91.03.20.31.30.41.7-0.4-0.41.71.00.4-0.21.00.30.41.8
Time >=10cm from walls, locomotor time 22.42.55.21.62.21.92.31.0-1.91.31.21.7-0.80.81.91.90.6
Bouts of movement, locomotor time 22.52.75.0-1.8-2.2-2.2-1.8-1.21.9-1.5-0.7-1.81.1-1.2-2.0-1.8-0.1
Total resting periods, locomotor time 23.03.26.4-1.8-2.5-2.4-2.2-1.22.0-1.7-0.9-1.81.2-1.4-2.2-1.8-0.4
Rest time, locomotor task time 20.10.10.5-0.2-0.2-0.4-0.0-0.20.20.40.40.10.7-0.3-0.2-0.00.2
Distance moved, locomotor task time 21.01.22.01.41.41.41.11.1-1.40.30.11.3-1.30.51.21.3-0.0
Vertical activity count, locomotor time 21.31.54.71.01.81.22.20.3-1.21.31.11.0-0.71.00.91.01.4
Weight adjusted by age1.31.52.91.41.41.71.01.3-1.60.20.11.5-1.20.11.71.5-0.4
Seeking ratio, delayed vs. immediate footshock0.20.32.20.0-0.60.1-0.80.20.1-0.20.1-0.20.2-1.50.1-0.2-0.5
Locomotion in novel chamber2.02.54.1-1.9-0.6-1.20.0-1.91.21.52.0-1.91.7-1.9-1.2-1.81.8
Locomotion in novel chamber post-restriction2.93.45.2-2.2-2.2-2.2-1.7-1.62.3-0.90.4-2.21.8-2.1-2.1-2.20.1
Progressive ratio0.10.10.50.2-0.20.3-0.50.3-0.20.2-0.70.2-0.00.50.20.1-0.5
Food seeking constrained by brief footshock0.30.41.7-0.1-0.7-0.6-0.80.10.3-1.3-0.9-0.1-0.30.5-0.4-0.1-0.9
Seeking ratio, punishment vs. effort0.10.10.6-0.2-0.2-0.50.1-0.20.2-0.80.2-0.20.0-0.2-0.3-0.20.1
Run reversals in cocaine runway, females0.50.51.30.40.90.51.1-0.5-0.21.11.10.4-0.40.40.50.41.0
Run reversals in cocaine runway, males0.40.42.90.20.40.5-0.60.6-0.4-0.5-0.80.3-0.20.40.40.3-1.7
Latency to leave start box in cocaine runway1.31.43.71.1-0.20.8-0.91.7-0.9-1.9-1.70.9-1.40.41.00.8-1.5
Latency to leave start box in cocaine runway, F1.01.15.30.8-0.60.6-1.01.3-0.5-2.3-1.20.5-1.0-0.40.80.5-1.4
Latency to leave start box in cocaine runway, M0.60.62.80.4-0.10.3-0.71.0-0.4-0.6-1.70.3-0.81.10.40.3-1.0
Cd content in liver0.50.51.5-0.5-1.1-0.7-1.20.00.5-0.8-1.1-0.6-0.40.0-0.7-0.6-0.5
Co content in liver0.20.20.8-0.5-0.6-0.9-0.3-0.40.4-0.5-0.2-0.40.1-0.0-0.6-0.40.2
Cu content in liver2.53.07.0-1.9-1.7-2.1-1.0-1.81.8-0.51.4-1.91.8-2.6-1.8-1.90.8
Fe content in liver3.23.86.82.31.82.01.22.1-2.2-0.5-1.22.2-2.62.42.32.2-0.6
K content in liver0.20.21.00.1-0.50.1-0.70.3-0.0-1.0-0.60.1-0.0-0.20.10.1-0.8
Mg content in liver0.10.10.60.2-0.20.2-0.40.3-0.2-0.7-0.50.2-0.10.10.30.2-0.7
Mn content in liver1.11.21.9-1.3-1.3-1.3-1.2-1.11.4-0.3-0.2-1.30.9-1.1-1.3-1.3-0.1
Na content in liver0.10.10.2-0.10.0-0.30.2-0.30.2-0.30.5-0.0-0.0-0.2-0.3-0.00.5
Rb content in liver0.10.10.40.10.30.40.6-0.1-0.10.30.50.10.10.20.30.10.6
Se content in liver1.11.43.5-1.2-1.3-1.9-1.1-1.21.4-0.90.2-1.30.4-1.2-1.4-1.30.1
Sr content in liver4.74.35.9-2.4-2.0-2.2-1.2-2.32.40.61.3-2.42.4-2.2-2.4-2.41.4
Zn content in liver0.40.41.3-0.6-0.8-0.8-0.8-0.40.6-0.60.2-0.60.6-1.2-0.6-0.6-0.5