# | tissue | modality | RNA phenotype | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | LASSO R2 | eQTL P | BLUP P | ENET P | LASSO P |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | gene expression | ENSRNOG00000011501 | 0.1000 | 0.0490 | 3.9e-10 | 0.090 | 0.086 | 0.083 | 0.083 | 3.2e-10 | 8.3e-10 | 1.8e-09 | 1.5e-09 |
2 | BLA | gene expression | ENSRNOG00000011501 | 0.1133 | 0.0621 | 2.4e-04 | 0.084 | 0.063 | 0.065 | 0.073 | 2.9e-05 | 2.9e-04 | 2.3e-04 | 9.3e-05 |
3 | Brain | gene expression | ENSRNOG00000011501 | 0.0850 | 0.0470 | 3.5e-05 | 0.027 | 0.041 | 0.049 | 0.053 | 1.5e-03 | 1.0e-04 | 2.2e-05 | 1.2e-05 |
4 | Brain | intron excision ratio | chr8:96922523:96923793 | 0.0475 | 0.0261 | 1.9e-04 | 0.039 | 0.025 | 0.022 | 0.026 | 1.6e-04 | 1.9e-03 | 3.9e-03 | 1.6e-03 |
5 | Brain | intron excision ratio | chr8:96922523:96941339 | 0.0543 | 0.0292 | 4.1e-05 | 0.047 | 0.038 | 0.043 | 0.038 | 3.3e-05 | 1.7e-04 | 7.7e-05 | 1.7e-04 |
6 | Brain | mRNA stability | ENSRNOG00000011501 | 0.3701 | 0.1110 | 0.0e+00 | 0.334 | 0.334 | 0.335 | 0.336 | 8.5e-32 | 8.2e-32 | 6.7e-32 | 4.5e-32 |
7 | IL | gene expression | ENSRNOG00000011501 | 0.1800 | 0.0970 | 3.7e-03 | 0.140 | 0.067 | 0.061 | 0.038 | 3.1e-04 | 1.1e-02 | 1.5e-02 | 4.3e-02 |
8 | IL | mRNA stability | ENSRNOG00000011501 | 0.2210 | 0.1180 | 5.4e-03 | 0.028 | 0.056 | 0.057 | 0.044 | 7.1e-02 | 1.8e-02 | 1.7e-02 | 3.2e-02 |
9 | Liver | gene expression | ENSRNOG00000011501 | 0.2900 | 0.0870 | 0.0e+00 | 0.211 | 0.202 | 0.209 | 0.210 | 5.8e-23 | 5.0e-22 | 9.2e-23 | 6.5e-23 |
10 | Liver | mRNA stability | ENSRNOG00000011501 | 0.0700 | 0.0345 | 8.2e-08 | 0.077 | 0.064 | 0.064 | 0.069 | 6.5e-09 | 1.2e-07 | 1.3e-07 | 3.8e-08 |
11 | NAcc | mRNA stability | ENSRNOG00000011501 | 0.2500 | 0.1140 | 2.2e-03 | 0.052 | 0.085 | 0.020 | 0.023 | 2.7e-02 | 6.0e-03 | 1.2e-01 | 1.0e-01 |
12 | NAcc2 | mRNA stability | ENSRNOG00000011501 | 0.0977 | 0.0531 | 6.2e-05 | 0.085 | 0.067 | 0.080 | 0.046 | 2.3e-05 | 1.6e-04 | 4.2e-05 | 1.6e-03 |
13 | OFC | mRNA stability | ENSRNOG00000011501 | 0.4267 | 0.1265 | 6.0e-08 | 0.312 | 0.297 | 0.253 | 0.322 | 3.6e-08 | 8.8e-08 | 1.0e-06 | 2.0e-08 |
14 | PL | gene expression | ENSRNOG00000011501 | 0.3225 | 0.1405 | 8.5e-04 | 0.093 | 0.088 | 0.135 | 0.117 | 3.3e-03 | 4.1e-03 | 4.4e-04 | 1.0e-03 |
15 | PL | mRNA stability | ENSRNOG00000011501 | 0.2230 | 0.1040 | 6.2e-04 | 0.224 | 0.100 | 0.129 | 0.181 | 4.9e-06 | 2.3e-03 | 5.9e-04 | 4.4e-05 |
16 | PL2 | gene expression | ENSRNOG00000011501 | 0.2000 | 0.0880 | 3.9e-08 | 0.103 | 0.149 | 0.149 | 0.130 | 3.2e-06 | 1.9e-08 | 1.8e-08 | 1.6e-07 |
17 | PL2 | mRNA stability | ENSRNOG00000011501 | 0.0831 | 0.0437 | 7.0e-05 | 0.086 | 0.078 | 0.061 | 0.076 | 2.1e-05 | 5.2e-05 | 3.1e-04 | 6.2e-05 |
All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method.
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
dissection: UMAP 1 of all traits | 3.2 | 11.7 | 32.7 | 0.1 | -0.1 | -5.7 | -3.5 | 4.6 | -4.6 | -0.1 | -4.4 | -0.3 | -4.5 | -1.8 | -2.2 | -3.7 | -2.0 | -4.6 | 1.9 | -4.5 |
retroperitoneal_fat_g | 0.6 | 2.1 | 7.7 | 0.8 | 0.7 | 2.8 | 1.2 | -1.9 | 1.8 | 1.0 | 1.4 | 1.0 | 1.7 | 0.2 | 0.3 | 1.2 | 1.9 | 1.8 | -0.1 | 1.7 |
body_g | 3.7 | 15.7 | 38.5 | -0.7 | -0.4 | 6.2 | 4.4 | -5.3 | 5.3 | -0.4 | 5.2 | -0.3 | 5.2 | 2.2 | 2.9 | 4.4 | 1.9 | 5.5 | -2.5 | 5.2 |
dissection: UMAP 3 of all traits | 0.2 | 0.4 | 1.6 | -0.8 | -0.4 | -0.1 | 0.5 | -0.6 | 0.5 | -0.6 | -0.3 | -0.8 | 0.4 | 1.0 | 0.5 | 0.8 | -1.3 | 0.8 | -0.7 | 0.4 |
kidney_right_g | 2.6 | 7.6 | 14.5 | -1.5 | -1.6 | 3.2 | 2.9 | -3.5 | 3.5 | -1.6 | 3.8 | -1.2 | 3.5 | 2.1 | 2.4 | 2.9 | 0.3 | 3.4 | -2.6 | 3.6 |
dissection: PC 3 of all traits | 1.6 | 3.8 | 7.7 | -2.2 | -2.8 | -0.3 | 2.0 | -1.4 | 1.4 | -2.3 | 1.7 | -2.4 | 1.3 | 2.3 | 2.2 | 2.0 | -2.4 | 1.4 | -2.1 | 1.3 |
dissection: PC 2 of all traits | 0.6 | 1.7 | 4.4 | 0.4 | -0.1 | -2.1 | -1.3 | 1.8 | -1.7 | -0.1 | -0.9 | 0.1 | -1.7 | -1.1 | -0.8 | -1.5 | 0.2 | -2.0 | 1.0 | -1.7 |
glucose_mg_dl | 0.2 | 0.4 | 1.3 | -0.2 | -0.3 | 0.3 | 0.8 | -0.5 | 0.4 | -0.3 | 0.8 | -0.2 | 0.5 | 1.0 | 0.5 | 1.1 | -0.7 | 0.6 | -0.3 | 0.6 |
heart_g | 0.6 | 0.9 | 2.8 | -0.4 | -0.5 | 0.8 | 0.7 | -1.0 | 1.0 | -0.7 | 1.3 | -0.3 | 1.1 | 1.7 | 0.6 | 1.5 | 0.6 | 0.9 | -0.1 | 1.3 |
os_mean | 0.4 | 0.5 | 1.7 | 0.1 | 0.4 | 1.3 | 1.0 | -0.6 | 0.6 | 0.1 | 0.9 | 0.5 | 0.9 | 0.0 | 0.4 | 0.9 | 0.4 | 0.9 | 0.1 | 0.8 |
EDL weight in grams | 1.9 | 7.5 | 14.0 | -1.4 | -0.9 | 3.5 | 3.6 | -3.3 | 3.4 | -0.7 | 3.7 | -0.9 | 3.2 | 1.7 | 3.0 | 3.2 | -0.1 | 3.6 | -1.9 | 3.5 |
Tibia length in mm | 1.1 | 3.0 | 9.5 | 2.1 | 2.5 | 3.1 | 0.5 | -0.9 | 1.0 | 2.4 | 1.1 | 2.5 | 0.9 | -2.1 | -0.4 | -0.4 | 2.7 | 1.0 | 0.9 | 0.9 |
sol weight in grams | 1.1 | 3.1 | 10.8 | 0.8 | 0.8 | 3.3 | 2.2 | -2.2 | 2.3 | 0.8 | 1.9 | 0.8 | 2.2 | 0.3 | 1.2 | 1.9 | 0.7 | 2.4 | -0.4 | 2.3 |
TA weight in grams | 0.8 | 2.7 | 7.7 | -0.1 | -0.0 | 2.8 | 1.6 | -2.2 | 2.3 | 0.1 | 2.3 | 0.1 | 2.0 | 0.9 | 1.1 | 1.9 | 0.6 | 2.2 | -0.9 | 2.2 |
Average time between licks in bursts | 0.4 | 0.6 | 1.4 | -1.0 | -0.8 | -0.0 | 1.0 | -0.6 | 0.6 | -1.1 | 0.5 | -1.0 | 0.7 | 0.2 | 1.2 | 0.2 | -1.0 | 0.6 | -1.0 | 0.6 |
Std. dev. time between licks in bursts | 0.6 | 0.7 | 3.7 | -0.9 | -1.1 | -1.1 | 0.2 | 0.1 | -0.2 | -1.2 | -0.5 | -1.1 | -0.1 | 0.7 | 0.5 | 0.1 | -1.9 | -0.1 | -1.0 | -0.1 |
Number of licking bursts | 0.9 | 1.0 | 2.5 | 1.4 | 1.5 | 0.3 | -0.4 | 0.6 | -0.6 | 1.4 | -0.4 | 1.5 | -0.7 | -1.6 | -0.7 | -0.9 | 1.2 | -0.6 | 1.2 | -0.6 |
Food consumed during 24 hour testing period | 1.4 | 1.7 | 5.4 | 1.4 | 1.5 | -0.5 | -1.0 | 1.5 | -1.4 | 1.4 | -0.5 | 1.5 | -1.5 | -0.3 | -1.3 | -0.2 | 1.7 | -1.2 | 2.3 | -1.2 |
Water consumed over 24 hour session | 0.7 | 0.8 | 2.4 | 1.2 | 1.4 | 0.5 | -0.3 | 0.5 | -0.4 | 1.2 | 0.1 | 1.4 | -0.6 | -0.8 | -0.5 | -0.4 | 1.5 | -0.6 | 1.4 | -0.4 |
Times rat made contact with spout | 0.3 | 0.4 | 1.4 | -0.2 | 0.0 | 0.6 | 1.1 | -0.5 | 0.6 | -0.0 | 1.2 | 0.1 | 0.4 | 0.4 | 0.8 | 0.9 | 0.7 | 0.4 | 0.3 | 0.4 |
Average drop size | 1.6 | 1.9 | 3.2 | 1.2 | 1.3 | -0.9 | -1.5 | 1.5 | -1.5 | 1.1 | -1.2 | 1.2 | -1.5 | -1.6 | -1.5 | -1.8 | 0.8 | -1.6 | 1.2 | -1.5 |
light_reinforcement_lr_relactive | 0.4 | 0.5 | 1.8 | 0.8 | 1.0 | 0.7 | 0.4 | -0.1 | 0.2 | 1.1 | 0.5 | 1.0 | 0.1 | -1.3 | 0.2 | -0.6 | 0.9 | 0.1 | 0.3 | 0.0 |
light_reinforcement_lr_active | 0.3 | 0.6 | 3.5 | 0.9 | 1.2 | 0.8 | -0.0 | -0.0 | 0.1 | 1.0 | -0.0 | 1.1 | 0.0 | -0.4 | -0.2 | 0.0 | 1.9 | -0.1 | 0.9 | -0.0 |
Delay discounting water rate 0 sec | 0.9 | 1.5 | 5.9 | 0.5 | 0.8 | 2.4 | 1.1 | -1.3 | 1.5 | 0.7 | 1.0 | 0.8 | 1.5 | 0.6 | 0.6 | 1.3 | 1.4 | 1.4 | 0.2 | 1.5 |
Median of all reaction times | 0.1 | 0.2 | 0.6 | 0.3 | 0.5 | -0.2 | 0.2 | 0.3 | -0.3 | 0.2 | -0.2 | 0.3 | -0.3 | -0.8 | 0.2 | -0.5 | 0.5 | -0.5 | 0.5 | -0.5 |
locomotor_testing_activity | 0.7 | 1.1 | 4.4 | 0.5 | 0.5 | 2.1 | 0.1 | -1.4 | 1.3 | 0.2 | 1.1 | 0.7 | 1.5 | 1.0 | -0.3 | 1.0 | 1.4 | 1.0 | -0.2 | 1.3 |
reaction_time_corr | 0.0 | 0.1 | 0.2 | 0.3 | 0.0 | 0.0 | -0.3 | 0.3 | -0.2 | 0.1 | -0.2 | 0.4 | -0.3 | 0.3 | -0.4 | 0.0 | 0.3 | -0.1 | 0.4 | 0.0 |
reaction_time_leftcorr | 0.0 | 0.1 | 0.2 | 0.3 | 0.0 | 0.0 | -0.3 | 0.3 | -0.2 | 0.1 | -0.2 | 0.4 | -0.3 | 0.3 | -0.4 | 0.0 | 0.3 | -0.1 | 0.4 | 0.0 |
delay_discounting_pc1800 | 0.4 | 0.6 | 2.2 | -1.0 | -0.7 | -0.5 | 0.2 | -0.3 | 0.4 | -1.0 | 0.5 | -1.1 | 0.1 | 1.5 | 0.3 | 0.9 | -1.1 | 0.4 | -0.7 | 0.3 |
reaction_time_falsealarm | 0.5 | 0.7 | 1.6 | 0.5 | 0.4 | -1.0 | -1.1 | 1.0 | -1.0 | 0.3 | -0.7 | 0.5 | -1.3 | -0.4 | -1.0 | -0.9 | 0.3 | -1.0 | 0.7 | -1.0 |
social_reinforcement_socialrfq | 0.2 | 0.2 | 0.7 | -0.0 | -0.3 | -0.8 | -0.5 | 0.5 | -0.5 | -0.3 | -0.4 | -0.2 | -0.4 | -0.3 | -0.3 | -0.8 | -0.3 | -0.8 | -0.4 | -0.5 |
reaction_time_pinit | 0.3 | 0.4 | 1.2 | 0.4 | 0.6 | -0.2 | -0.3 | 0.5 | -0.5 | 0.6 | -0.9 | 0.5 | -0.7 | -1.1 | -0.2 | -1.0 | 0.4 | -0.6 | 0.5 | -0.6 |
reaction_time_pinit_slope | 0.6 | 0.8 | 2.5 | 0.3 | -0.1 | -1.6 | -1.1 | 1.3 | -1.3 | -0.1 | -0.3 | 0.1 | -1.2 | 0.3 | -1.0 | -0.2 | -0.4 | -1.0 | 1.0 | -1.1 |
reaction_time_peropfalsealarm_slope | 0.9 | 1.1 | 2.0 | -0.8 | -0.5 | 1.0 | 1.0 | -1.4 | 1.4 | -0.6 | 0.8 | -0.8 | 1.4 | 1.3 | 1.1 | 1.3 | 0.6 | 1.1 | -0.6 | 1.3 |
soc_socialavgti | 0.5 | 0.6 | 1.6 | 0.1 | 0.2 | -1.0 | -1.2 | 1.0 | -1.1 | 0.1 | -1.1 | 0.2 | -0.9 | -0.3 | -0.7 | -0.8 | 0.0 | -1.2 | 0.6 | -1.0 |
reaction_time_peropinit_slope | 0.3 | 0.3 | 0.9 | -0.5 | -0.7 | -0.9 | -0.7 | 0.3 | -0.4 | -0.9 | -0.2 | -0.7 | -0.2 | 1.0 | -0.1 | 0.1 | -0.4 | -0.3 | 0.2 | -0.1 |
reaction_time_meanrt_slope | 1.0 | 1.2 | 2.7 | 1.5 | 1.4 | 0.6 | -0.4 | 0.6 | -0.5 | 1.6 | -0.5 | 1.6 | -0.6 | -1.6 | -1.0 | -0.7 | 1.4 | -0.4 | 1.4 | -0.7 |
reaction_time_devmedrt_slope | 0.3 | 0.3 | 1.5 | 0.5 | 0.4 | 0.9 | -0.1 | -0.3 | 0.3 | 0.6 | 0.4 | 0.6 | 0.4 | -0.2 | -0.5 | 0.2 | 1.2 | 0.4 | 0.3 | 0.3 |
pavca_ny_levercs_d4d5 | 0.5 | 0.7 | 2.1 | -0.4 | -0.2 | 0.8 | 1.0 | -0.9 | 0.9 | -0.3 | 1.4 | -0.4 | 1.0 | 1.1 | 0.7 | 1.5 | 0.3 | 0.9 | -0.4 | 0.8 |
pavca_ny_d2_magazine_cs | 0.4 | 0.5 | 1.6 | 0.3 | 0.3 | 1.2 | 0.2 | -0.8 | 0.8 | 0.4 | 0.4 | 0.3 | 0.7 | 0.8 | 0.0 | 1.0 | 0.7 | 0.9 | 0.2 | 0.8 |
ccp_trial_3_saline_dist_mm | 0.7 | 0.9 | 2.0 | -0.2 | -0.3 | 1.4 | 1.0 | -1.2 | 1.3 | -0.2 | 1.2 | -0.1 | 1.4 | 0.6 | 0.6 | 1.0 | -0.1 | 1.3 | -0.7 | 1.4 |
pavca_ny_d5_magazine_ncs | 3.1 | 4.1 | 9.7 | 0.5 | -0.0 | -3.1 | -2.3 | 2.8 | -2.9 | 0.1 | -2.6 | 0.2 | -2.8 | -0.7 | -1.9 | -2.0 | -1.2 | -2.5 | 1.1 | -2.5 |
ccp_change_in_locomotor_activity | 0.8 | 1.0 | 3.6 | -0.8 | -0.9 | -1.6 | -1.0 | 0.7 | -0.8 | -1.1 | -1.3 | -1.0 | -0.6 | 0.7 | -0.6 | -0.6 | -1.9 | -0.7 | -0.7 | -0.7 |
Conditioned locomotion | 0.2 | 0.3 | 1.3 | -0.5 | -1.2 | -0.1 | 0.1 | -0.1 | 0.2 | -0.8 | 0.6 | -0.7 | 0.4 | 0.5 | 0.4 | 0.4 | -0.5 | 0.4 | -0.7 | 0.4 |
Total sessions with >9 infusions | 0.1 | 0.1 | 0.6 | 0.3 | 0.1 | 0.2 | -0.3 | 0.1 | 0.0 | 0.2 | 0.1 | 0.3 | 0.1 | 0.2 | -0.4 | 0.2 | 0.8 | 0.1 | 0.3 | 0.1 |
Velocity during novelty place preference test | 3.1 | 4.5 | 7.7 | -1.4 | -1.4 | 2.3 | 2.2 | -2.6 | 2.6 | -1.5 | 2.2 | -1.4 | 2.6 | 1.9 | 2.0 | 2.2 | -0.4 | 2.8 | -2.5 | 2.5 |
crf_mi_active_responses | 0.1 | 0.1 | 0.3 | 0.4 | 0.3 | 0.2 | -0.1 | 0.2 | -0.1 | 0.5 | -0.1 | 0.4 | -0.1 | -0.6 | -0.2 | -0.3 | -0.1 | -0.1 | 0.0 | -0.2 |
pavca_mi_d1_avg_mag_lat | 0.0 | 0.0 | 0.2 | -0.2 | -0.3 | -0.2 | -0.1 | 0.0 | -0.0 | -0.4 | -0.1 | -0.2 | -0.0 | 0.4 | -0.1 | 0.2 | 0.1 | -0.0 | -0.1 | -0.0 |
pavca_mi_d3_magazine_ncs | 0.5 | 0.5 | 0.8 | 0.7 | 0.7 | -0.4 | -0.9 | 0.7 | -0.7 | 0.8 | -0.6 | 0.8 | -0.7 | -0.7 | -0.9 | -0.8 | 0.3 | -0.8 | 0.7 | -0.7 |
pavca_mi_d1_prob_lev | 1.0 | 1.3 | 3.1 | -0.1 | -0.0 | 1.8 | 1.6 | -1.4 | 1.5 | -0.2 | 1.2 | -0.1 | 1.5 | -0.0 | 1.2 | 0.7 | -0.6 | 1.6 | -1.3 | 1.5 |
pavca_mi_d1_avg_lev_lat | 0.5 | 0.8 | 2.9 | -0.5 | -0.6 | -1.7 | -1.1 | 1.0 | -1.1 | -0.4 | -1.1 | -0.6 | -1.1 | 0.6 | -0.6 | -0.3 | -0.2 | -1.1 | 0.8 | -1.0 |
pavca_mi_d3_prob_mag | 0.3 | 0.3 | 0.9 | 0.7 | 0.9 | 0.2 | -0.8 | 0.1 | -0.2 | 0.8 | -0.8 | 0.7 | -0.2 | -0.1 | -0.8 | -0.4 | 0.7 | -0.3 | 0.8 | -0.2 |
Total cortical area | 0.1 | 0.1 | 0.4 | -0.4 | 0.1 | 0.4 | 0.5 | -0.4 | 0.4 | -0.1 | -0.1 | -0.3 | 0.3 | 0.5 | 0.6 | 0.6 | 0.1 | 0.3 | -0.1 | 0.3 |
tb_th_sd | 0.1 | 0.1 | 0.6 | 0.3 | 0.4 | 0.7 | -0.3 | -0.4 | 0.3 | 0.3 | -0.1 | 0.4 | 0.3 | -0.3 | -0.2 | -0.3 | 0.4 | 0.2 | -0.2 | 0.2 |
Cortical porosity | 2.5 | 2.7 | 5.2 | -2.3 | -2.2 | -0.5 | 1.5 | -1.1 | 1.0 | -2.2 | 1.3 | -2.3 | 1.0 | 1.7 | 1.8 | 1.2 | -2.1 | 1.0 | -2.0 | 1.1 |
length | 0.7 | 1.4 | 4.4 | 0.0 | 0.0 | 2.1 | 1.3 | -1.5 | 1.5 | 0.2 | 1.6 | 0.1 | 1.4 | 0.4 | 0.9 | 1.3 | 0.6 | 1.5 | -0.6 | 1.6 |
Trabecular tissue density | 1.3 | 1.8 | 3.0 | -1.3 | -1.1 | 0.8 | 1.0 | -1.5 | 1.5 | -1.3 | 1.6 | -1.4 | 1.5 | 1.4 | 1.0 | 1.3 | -0.6 | 1.4 | -1.7 | 1.4 |
ctth_sd | 0.3 | 0.3 | 1.0 | -0.7 | -0.5 | -0.9 | 0.0 | 0.4 | -0.4 | -0.5 | -0.5 | -0.7 | -0.5 | 1.0 | 0.2 | 0.6 | -0.7 | -0.3 | 0.1 | -0.3 |
tautz: manual_spc7 | 3.4 | 5.1 | 8.2 | 1.8 | 1.7 | -2.0 | -2.4 | 2.7 | -2.7 | 1.7 | -2.4 | 1.9 | -2.7 | -1.5 | -2.3 | -1.9 | 1.6 | -2.7 | 2.9 | -2.7 |
tautz: manual_mpc15 | 2.2 | 3.1 | 5.8 | -1.7 | -1.6 | 1.2 | 1.3 | -1.9 | 1.9 | -1.6 | 1.2 | -1.8 | 2.0 | 2.1 | 1.4 | 1.8 | -1.6 | 2.0 | -2.4 | 2.0 |
tautz: manual_mpc18 | 2.3 | 3.2 | 5.0 | -1.7 | -1.5 | 1.3 | 2.1 | -1.9 | 1.9 | -1.5 | 1.5 | -1.5 | 1.9 | 1.7 | 2.2 | 1.8 | -1.7 | 1.9 | -2.0 | 1.9 |
tautz: manual_spc15 | 0.0 | 0.0 | 0.3 | 0.0 | 0.0 | 0.1 | 0.5 | -0.0 | 0.1 | -0.0 | -0.1 | -0.1 | 0.1 | -0.2 | 0.5 | -0.0 | -0.1 | 0.0 | 0.1 | 0.0 |
tautz: manual_spc21 | 1.5 | 1.9 | 4.5 | -0.7 | -0.7 | 1.6 | 1.2 | -1.7 | 1.7 | -0.6 | 1.5 | -0.8 | 1.7 | 1.8 | 0.9 | 2.1 | 0.6 | 1.7 | -0.7 | 1.7 |
tautz: manual_spc9 | 0.3 | 0.5 | 1.3 | 0.1 | 0.1 | -0.8 | -1.0 | 0.7 | -0.7 | 0.1 | -0.9 | 0.1 | -0.8 | -0.6 | -0.8 | -1.1 | -0.7 | -0.7 | -0.0 | -0.7 |
tautz: manual_mpc3 | 0.6 | 1.0 | 4.0 | 0.9 | 1.3 | 0.0 | -0.3 | 0.7 | -0.7 | 1.3 | -0.3 | 1.3 | -0.7 | -2.0 | -0.2 | -1.5 | 0.4 | -0.7 | 1.1 | -0.7 |
tautz: manual_spc12 | 1.4 | 1.9 | 3.5 | 1.3 | 1.0 | -1.2 | -1.1 | 1.7 | -1.7 | 1.0 | -1.9 | 1.3 | -1.7 | -0.9 | -1.0 | -1.2 | 0.7 | -1.6 | 1.9 | -1.6 |
tautz: manual_spc14 | 0.8 | 1.2 | 2.6 | -1.0 | -0.9 | 0.8 | 1.0 | -1.2 | 1.2 | -1.0 | 1.1 | -0.9 | 1.1 | 1.6 | 1.0 | 1.6 | -0.6 | 1.1 | -1.0 | 1.1 |
tautz: manual_spc8 | 2.3 | 3.2 | 5.5 | -1.0 | -0.9 | 2.1 | 2.2 | -2.2 | 2.2 | -0.9 | 2.3 | -0.9 | 2.2 | 1.5 | 2.0 | 2.1 | -0.1 | 2.2 | -1.5 | 2.2 |
tautz: manual_mpc7 | 1.1 | 1.3 | 2.8 | -1.7 | -1.5 | -0.0 | 1.1 | -0.9 | 0.8 | -1.5 | 1.1 | -1.4 | 0.9 | 1.1 | 1.4 | 0.9 | -1.1 | 0.9 | -1.2 | 0.9 |
tautz: manual_mpc16 | 0.3 | 0.3 | 0.8 | -0.5 | -0.2 | 0.7 | 0.3 | -0.8 | 0.8 | -0.3 | 0.2 | -0.4 | 0.8 | 0.3 | 0.4 | 0.2 | -0.7 | 0.8 | -0.9 | 0.8 |
tautz: manual_mpc4 | 0.6 | 0.7 | 1.0 | 0.8 | 1.0 | -0.3 | -0.7 | 0.8 | -0.7 | 1.0 | -0.8 | 0.9 | -0.8 | -1.0 | -0.7 | -0.8 | 0.8 | -0.8 | 0.9 | -0.8 |
tautz: manual_mpc10 | 1.0 | 1.5 | 4.1 | 1.4 | 1.8 | 2.0 | 0.6 | -0.5 | 0.6 | 1.8 | 0.8 | 1.7 | 0.5 | -1.8 | -0.0 | -0.3 | 1.8 | 0.5 | 0.6 | 0.5 |
tautz: manual_mpc5 | 0.3 | 0.4 | 1.2 | 0.9 | 0.7 | 0.9 | 1.0 | -0.1 | 0.3 | 0.9 | 0.2 | 0.9 | 0.1 | -1.1 | 0.6 | 0.0 | 0.4 | 0.1 | 0.3 | 0.1 |
tautz: manual_spc22 | 2.8 | 4.2 | 7.0 | -1.7 | -1.8 | 1.5 | 2.0 | -2.3 | 2.2 | -1.8 | 2.1 | -1.8 | 2.2 | 2.1 | 2.0 | 2.3 | -1.2 | 2.3 | -2.6 | 2.3 |
tautz: manual_mpc14 | 0.9 | 1.5 | 2.2 | 1.2 | 1.3 | -1.0 | -1.0 | 1.4 | -1.4 | 1.2 | -1.2 | 1.2 | -1.4 | -1.5 | -0.9 | -1.5 | 0.2 | -1.4 | 1.2 | -1.4 |
tautz: manual_mpc12 | 0.1 | 0.2 | 0.5 | -0.5 | -0.7 | 0.3 | 0.1 | -0.4 | 0.4 | -0.5 | 0.2 | -0.5 | 0.3 | 0.7 | 0.3 | 0.4 | 0.0 | 0.4 | -0.2 | 0.4 |
tautz: manual_mcs | 1.3 | 1.5 | 4.5 | 1.8 | 1.8 | 1.4 | -0.4 | 0.1 | -0.1 | 1.9 | -0.3 | 1.9 | -0.1 | -2.1 | -0.8 | -1.2 | 1.4 | -0.2 | 1.0 | -0.2 |
tautz: manual_spc17 | 1.1 | 1.6 | 4.2 | 0.9 | 0.6 | -1.3 | -1.4 | 1.5 | -1.5 | 0.6 | -2.1 | 0.7 | -1.5 | -0.7 | -1.2 | -1.3 | -0.6 | -1.5 | 1.0 | -1.5 |
tautz: manual_spc24 | 0.2 | 0.3 | 1.1 | 0.5 | 0.5 | 1.1 | 0.6 | -0.5 | 0.6 | 0.5 | 0.6 | 0.6 | 0.5 | -0.7 | 0.2 | 0.1 | 0.6 | 0.5 | -0.3 | 0.5 |
tautz: manual_spc4 | 0.7 | 1.0 | 1.5 | -1.1 | -1.2 | 0.7 | 0.8 | -1.1 | 1.1 | -1.2 | 0.9 | -0.9 | 1.1 | 0.6 | 0.9 | 0.6 | -0.3 | 1.2 | -1.1 | 1.2 |
tautz: manual_mpc9 | 0.5 | 0.6 | 2.0 | -1.1 | -1.2 | -0.7 | 0.2 | -0.3 | 0.2 | -1.3 | 0.6 | -1.4 | 0.2 | 1.4 | 0.5 | 0.8 | -0.6 | 0.3 | -0.5 | 0.3 |
tautz: manual_spc2 | 0.0 | 0.1 | 0.2 | -0.2 | -0.1 | 0.0 | 0.3 | -0.1 | 0.2 | -0.1 | -0.2 | -0.2 | 0.1 | 0.4 | 0.3 | 0.4 | -0.5 | 0.1 | -0.2 | 0.1 |
tautz: manual_spc13 | 0.3 | 0.4 | 1.0 | -0.3 | -0.1 | 1.0 | 0.9 | -0.7 | 0.8 | -0.1 | 0.4 | -0.1 | 0.8 | 0.5 | 0.8 | 0.8 | -0.1 | 0.8 | -0.3 | 0.8 |
tautz: manual_mpc19 | 2.3 | 2.6 | 4.4 | 1.0 | 0.7 | -1.7 | -2.0 | 2.1 | -2.1 | 0.8 | -1.7 | 1.0 | -2.1 | -1.2 | -1.8 | -1.7 | 0.6 | -2.0 | 1.4 | -2.0 |
tautz: manual_spc10 | 0.3 | 0.4 | 0.7 | 0.5 | 0.3 | -0.7 | -0.2 | 0.8 | -0.8 | 0.3 | -0.6 | 0.3 | -0.8 | -0.8 | -0.3 | -0.8 | -0.3 | -0.8 | 0.3 | -0.8 |
tautz: manual_spc11 | 0.2 | 0.2 | 1.3 | 0.7 | 0.4 | 0.3 | 0.6 | 0.1 | -0.0 | 0.5 | 0.1 | 0.6 | -0.2 | -1.2 | 0.5 | -0.5 | -0.2 | -0.2 | -0.3 | -0.2 |
tautz: manual_spc23 | 0.6 | 1.0 | 1.8 | -1.1 | -1.3 | 0.1 | 1.1 | -0.8 | 0.8 | -1.4 | 1.1 | -1.1 | 0.8 | 1.2 | 1.1 | 1.0 | -0.4 | 0.8 | -1.1 | 0.8 |
tautz: manual_spc6 | 2.0 | 2.9 | 4.2 | -1.2 | -1.2 | 1.7 | 1.9 | -2.0 | 2.0 | -1.1 | 1.8 | -1.1 | 2.0 | 1.6 | 1.7 | 2.1 | -0.2 | 2.0 | -1.8 | 2.0 |
tautz: manual_spc20 | 0.6 | 0.7 | 2.2 | -0.2 | -0.1 | 1.5 | 0.4 | -1.3 | 1.2 | -0.1 | 0.8 | -0.1 | 1.2 | 0.5 | 0.2 | 0.7 | 0.7 | 1.2 | -0.7 | 1.2 |
tautz: manual_mpc17 | 0.1 | 0.1 | 0.4 | 0.5 | 0.3 | 0.6 | 0.2 | -0.3 | 0.3 | 0.4 | 0.2 | 0.4 | 0.2 | -0.2 | -0.1 | 0.1 | 0.0 | 0.2 | -0.0 | 0.2 |
tautz: manual_mpc2 | 0.2 | 0.3 | 0.8 | -0.3 | -0.2 | 0.2 | 0.9 | -0.5 | 0.5 | -0.3 | 0.9 | -0.4 | 0.5 | 0.2 | 0.9 | 0.6 | 0.0 | 0.5 | 0.0 | 0.5 |
tautz: manual_spc1 | 0.2 | 0.2 | 1.1 | 0.4 | 0.2 | 0.8 | 0.2 | -0.3 | 0.4 | 0.3 | 0.9 | 0.5 | 0.3 | -1.0 | 0.0 | -0.4 | 0.3 | 0.4 | -0.2 | 0.4 |
tautz: manual_spc16 | 2.0 | 2.7 | 6.5 | -0.6 | -0.4 | 2.6 | 1.6 | -2.2 | 2.3 | -0.4 | 1.8 | -0.6 | 2.3 | 0.9 | 1.3 | 1.6 | 0.5 | 2.2 | -1.3 | 2.2 |
tautz: manual_mpc13 | 0.1 | 0.1 | 0.4 | -0.3 | -0.3 | 0.1 | 0.1 | -0.2 | 0.2 | -0.3 | 0.1 | -0.1 | 0.2 | 0.6 | 0.1 | 0.6 | 0.2 | 0.2 | -0.3 | 0.2 |
tautz: manual_spc5 | 2.4 | 3.3 | 6.0 | 2.1 | 2.3 | -0.3 | -1.4 | 1.7 | -1.6 | 2.2 | -1.2 | 2.2 | -1.7 | -2.4 | -1.6 | -1.9 | 1.5 | -1.7 | 2.2 | -1.7 |
tautz: manual_spc3 | 0.2 | 0.2 | 0.6 | 0.5 | 0.3 | -0.7 | 0.0 | 0.7 | -0.7 | 0.4 | 0.1 | 0.3 | -0.7 | -0.3 | -0.1 | -0.1 | -0.1 | -0.7 | 0.7 | -0.7 |
tautz: manual_mpc6 | 0.5 | 0.6 | 1.6 | 0.6 | 0.4 | -0.7 | -1.3 | 0.7 | -0.8 | 0.3 | -0.7 | 0.5 | -0.8 | 0.3 | -1.3 | -0.2 | 0.7 | -0.8 | 0.9 | -0.8 |
tautz: manual_spc18 | 0.3 | 0.3 | 0.9 | -0.7 | -0.9 | -0.7 | -0.6 | 0.1 | -0.1 | -0.9 | -0.4 | -0.9 | -0.1 | 0.8 | -0.3 | 0.0 | -0.9 | -0.1 | -0.5 | -0.1 |
tautz: manual_mpc11 | 1.0 | 1.3 | 1.8 | 1.3 | 1.1 | -0.6 | -1.2 | 1.1 | -1.1 | 1.1 | -0.6 | 1.0 | -1.2 | -1.4 | -1.2 | -1.2 | 1.2 | -1.1 | 1.1 | -1.1 |
tautz: manual_spc19 | 0.1 | 0.2 | 0.6 | -0.7 | -0.3 | 0.2 | 0.5 | -0.4 | 0.4 | -0.3 | 0.8 | -0.5 | 0.5 | -0.1 | 0.6 | 0.2 | 0.2 | 0.4 | -0.3 | 0.4 |
tautz: manual_mpc8 | 1.1 | 1.5 | 5.3 | 1.0 | 1.3 | -0.4 | -0.7 | 1.2 | -1.1 | 1.4 | -0.7 | 1.2 | -1.2 | -2.3 | -0.5 | -1.9 | 1.1 | -1.2 | 0.9 | -1.2 |
tautz: manual_mpc1 | 0.2 | 0.2 | 1.0 | -0.2 | -0.0 | -1.0 | -0.5 | 0.7 | -0.7 | -0.1 | -0.4 | -0.2 | -0.6 | 0.2 | -0.3 | -0.2 | 0.4 | -0.6 | 0.6 | -0.6 |
Sum of all infusions from LGA sessions | 0.2 | 0.3 | 1.2 | -0.6 | 0.2 | 0.4 | 0.7 | -0.1 | 0.2 | 0.1 | 0.9 | 0.2 | 0.3 | -0.8 | 0.9 | -0.2 | 1.1 | 0.1 | 0.4 | 0.3 |
Ambulatory time at time1 of open field | 1.4 | 1.5 | 2.4 | -0.6 | -0.9 | 1.2 | 1.4 | -1.4 | 1.4 | -0.9 | 1.5 | -0.9 | 1.4 | 1.3 | 1.1 | 1.4 | -0.6 | 1.5 | -1.4 | 1.3 |
dd_expon_k | 0.1 | 0.1 | 0.4 | 0.1 | -0.4 | 0.3 | 0.1 | -0.3 | 0.6 | -0.3 | 0.5 | -0.1 | 0.4 | 0.6 | 0.0 | 0.5 | 0.1 | 0.4 | -0.2 | 0.3 |
Delay discounting AUC-traditional | 0.4 | 0.4 | 1.1 | 0.4 | 0.7 | -0.3 | -0.4 | 0.6 | -0.8 | 0.8 | -0.7 | 0.6 | -0.7 | -1.0 | -0.4 | -0.8 | 0.4 | -0.7 | 0.7 | -0.7 |
The total number of resting periods in time1 | 0.5 | 0.5 | 1.9 | 0.8 | 1.3 | 0.7 | 0.0 | 0.0 | 0.0 | 1.3 | 0.3 | 1.0 | -0.0 | -1.4 | -0.1 | -0.4 | 0.9 | 0.1 | 0.6 | 0.2 |
Area under the delay curve | 0.4 | 0.4 | 1.1 | 0.4 | 0.7 | -0.3 | -0.4 | 0.6 | -0.8 | 0.8 | -0.7 | 0.6 | -0.7 | -1.0 | -0.4 | -0.8 | 0.4 | -0.7 | 0.7 | -0.7 |
punishment | 0.4 | 0.5 | 1.6 | -1.0 | -0.5 | -0.2 | 0.8 | -0.3 | 0.3 | -0.7 | 0.3 | -0.8 | 0.4 | -0.1 | 1.3 | -0.2 | -1.2 | 0.1 | -1.0 | 0.4 |
runstartmale1 | 2.0 | 1.9 | 4.1 | 0.6 | 0.6 | -2.0 | -0.9 | 1.9 | -1.9 | 0.6 | -1.6 | 0.9 | -1.7 | -1.7 | -0.7 | -1.9 | -0.5 | -1.7 | 0.5 | -1.7 |
locomotor2 | 1.3 | 1.6 | 2.9 | 1.2 | 1.5 | -0.3 | -1.4 | 1.1 | -1.1 | 1.6 | -1.0 | 1.3 | -1.3 | -1.0 | -1.6 | -1.0 | 1.5 | -1.1 | 1.7 | -1.1 |
Weight adjusted by age | 2.0 | 2.2 | 4.8 | -0.1 | -0.3 | 2.2 | 1.6 | -2.0 | 2.0 | -0.3 | 1.7 | -0.5 | 2.1 | 0.8 | 1.2 | 1.6 | 1.0 | 2.1 | -0.8 | 2.0 |
Liver selenium concentration | 0.9 | 1.1 | 1.8 | 1.1 | 0.7 | -0.9 | -1.1 | 1.3 | -1.3 | 0.9 | -1.2 | 0.8 | -1.3 | -1.2 | -1.2 | -1.1 | 0.5 | -1.1 | 1.1 | -1.1 |
Liver rubidium concentration | 0.2 | 0.3 | 1.2 | 0.6 | 0.7 | 0.6 | -0.2 | 0.2 | -0.2 | 0.8 | 0.0 | 0.7 | -0.2 | -0.3 | -0.4 | 0.1 | 1.1 | 0.0 | 0.9 | -0.1 |
Liver iron concentration | 1.2 | 1.4 | 3.1 | 1.5 | 1.6 | 0.2 | -0.6 | 1.0 | -0.9 | 1.7 | -0.5 | 1.6 | -0.9 | -1.3 | -0.9 | -0.6 | 1.6 | -0.9 | 1.8 | -0.9 |
Liver cobalt concentration | 0.9 | 1.0 | 2.4 | -1.5 | -1.4 | -0.5 | 0.8 | -0.6 | 0.5 | -1.5 | 0.6 | -1.5 | 0.6 | 1.0 | 1.2 | 0.5 | -1.6 | 0.4 | -1.1 | 0.5 |
Liver cadmium concentration | 0.1 | 0.2 | 0.9 | -0.1 | 0.2 | -0.4 | 0.3 | 0.2 | -0.2 | 0.2 | -0.1 | -0.1 | -0.4 | -0.9 | 0.4 | -0.7 | -0.2 | -0.6 | -0.0 | -0.5 |
Liver zinc concentration | 0.1 | 0.1 | 0.1 | 0.1 | -0.1 | -0.2 | -0.2 | 0.3 | -0.4 | -0.2 | 0.3 | 0.1 | -0.2 | 0.3 | -0.3 | 0.2 | 0.3 | -0.2 | 0.0 | -0.2 |
Liver sodium concentration | 0.1 | 0.1 | 0.2 | 0.4 | 0.2 | -0.3 | -0.4 | 0.3 | -0.3 | 0.1 | -0.4 | 0.1 | -0.3 | -0.4 | -0.4 | -0.4 | -0.4 | -0.2 | -0.2 | -0.2 |
Liver manganese concentration | 1.6 | 1.9 | 2.8 | -1.3 | -1.3 | 0.6 | 1.7 | -1.5 | 1.4 | -1.3 | 1.4 | -1.4 | 1.5 | 1.1 | 1.7 | 1.3 | -1.2 | 1.4 | -1.5 | 1.5 |
For each tested trait, stats based on TWAS chi2 (squared Z-score) for the above models are shown. Avg chi2 ratio is the mean chi2 across all models for this gene, divided by the mean chi2 across all models for all genes. Avg chi2 is the mean chi2 across all models for this gene. Max chi2 is the highest chi2 across all models for this gene.
The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.