Hub : Genes

Ccdc39

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000011440 0.09 0.06 9.3e-04 0.07 0.04 0.02 0.05 2.1e-04 2.4e-03 3.2e-02 1.1e-03
2 BLA mRNA stability ENSRNOG00000011440 0.51 0.15 0.0e+00 0.38 0.45 0.42 0.48 3.9e-21 9.7e-27 4.5e-24 2.2e-28
3 Brain gene expression ENSRNOG00000011440 0.15 0.07 4.9e-11 0.11 0.12 0.12 0.09 4.0e-10 5.5e-11 7.2e-11 1.5e-08
4 Brain intron excision ratio chr2:116690367:116692431 0.1 0.06 8.3e-07 0.09 0.06 0.06 0.07 2.0e-08 1.5e-06 2.8e-06 2.2e-07
5 Brain intron excision ratio chr2:116692622:116695324 0.08 0.05 3.5e-05 0.07 0.04 0.04 0.05 1.0e-06 1.2e-04 8.0e-05 1.4e-05
6 Brain mRNA stability ENSRNOG00000011440 0.6 0.18 0.0e+00 0.22 0.24 0.26 0.23 4.0e-20 6.7e-22 9.8e-24 4.6e-21
7 IL intron excision ratio chr2:116688917:116690264 0.16 0.1 5.8e-03 0.08 0.04 -0.01 0.02 6.8e-03 3.4e-02 5.6e-01 1.2e-01
8 IL mRNA stability ENSRNOG00000011440 0.43 0.16 3.1e-09 0.24 0.32 0.33 0.36 2.0e-06 2.1e-08 8.2e-09 1.3e-09
9 LHb isoform ratio ENSRNOT00000065469 0.13 0.09 9.5e-03 -0 0.02 -0 0.01 3.6e-01 1.2e-01 3.7e-01 1.6e-01
10 NAcc gene expression ENSRNOG00000011440 0.06 0.04 2.9e-03 0.02 0.01 0.02 0.02 7.2e-03 2.3e-02 8.8e-03 8.4e-03
11 NAcc intron excision ratio chr2:116688917:116690264 0.05 0.03 7.6e-05 0.01 0.05 0.04 0.03 3.9e-02 1.5e-04 1.0e-03 1.7e-03
12 NAcc mRNA stability ENSRNOG00000011440 0.32 0.14 0.0e+00 0.32 0.3 0.31 0.31 2.0e-24 1.5e-22 2.7e-23 1.2e-23
13 OFC mRNA stability ENSRNOG00000011440 0.4 0.16 4.1e-07 0.23 0.19 0.21 0.23 3.0e-06 2.4e-05 8.6e-06 3.4e-06
14 PL gene expression ENSRNOG00000011440 0.17 0.09 4.8e-08 0.1 0.08 0.11 0.11 3.8e-08 5.6e-07 1.6e-08 1.7e-08
15 PL mRNA stability ENSRNOG00000011440 0.39 0.12 0.0e+00 0.41 0.42 0.43 0.44 2.9e-33 1.7e-34 1.0e-35 3.2e-36

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail1.13.66.82.6-1.82.4-1.81.8-1.7-2.5-1.4-1.11.5-2.3-1.4-1.52.3-1.5
BMI without tail1.42.95.51.8-2.11.2-0.40.4-2.3-1.7-2.0-1.9-0.1-2.2-2.0-2.00.9-2.0
Body weight0.31.33.51.5-0.31.9-1.71.7-0.2-1.6-0.10.21.3-0.9-0.1-0.11.7-0.1
Epididymis fat weight0.51.12.2-0.11.20.3-0.90.91.50.21.41.41.01.01.31.30.51.3
Glucose1.21.93.2-1.81.7-0.90.4-0.41.51.51.71.5-0.11.81.61.5-0.81.6
Heart weight0.20.30.70.2-0.6-0.50.7-0.7-0.50.1-0.7-0.9-0.1-0.5-0.7-0.7-0.3-0.7
Left kidney weight0.10.20.8-0.3-0.50.20.4-0.4-0.10.2-0.5-0.4-0.9-0.2-0.6-0.5-0.3-0.5
Right kidney weight0.30.91.61.1-1.11.3-0.50.5-0.5-1.1-1.0-0.70.1-1.2-1.0-1.00.9-1.0
Tail length0.20.61.9-0.8-0.2-0.81.1-1.1-0.50.7-0.5-0.5-1.40.1-0.4-0.4-1.1-0.4
Length with tail0.20.72.0-1.40.9-0.70.6-0.60.71.00.60.6-0.71.00.70.8-0.90.8
Length without tail0.81.73.4-0.81.70.4-0.80.81.60.41.71.90.81.41.71.70.51.8
Liver weight, left1.32.24.20.41.51.3-1.71.71.5-0.31.82.11.11.11.81.71.21.7
Liver weight, right0.10.20.40.20.50.3-0.40.40.2-0.00.50.60.40.40.50.60.30.5
Parametrial fat weight0.71.33.61.30.11.9-1.71.70.7-1.30.50.91.2-0.30.40.51.70.4
Retroperitoneal fat weight0.31.12.00.70.71.2-1.41.41.2-0.71.01.21.30.30.91.01.30.9
Intraocular pressure0.91.33.5-1.01.4-0.90.2-0.21.91.11.21.1-0.51.41.31.3-0.91.4
Extensor digitorum longus weight0.83.27.52.7-1.12.3-2.32.3-0.8-2.7-0.8-0.42.2-1.9-0.8-0.72.3-0.8
Soleus weight6.619.337.62.3-5.90.62.1-2.1-4.9-2.2-6.1-5.8-2.2-5.1-6.1-6.0-0.1-6.0
Tibialis anterior weight1.75.812.73.6-1.63.1-3.03.0-1.3-3.5-1.2-0.72.6-2.6-1.3-1.03.2-1.2
Tibia length2.36.412.8-0.93.40.2-1.51.52.71.13.53.51.12.93.63.40.43.5
Number of licking bursts1.82.15.42.3-1.61.7-0.90.9-0.7-1.9-1.4-1.00.7-1.8-1.4-1.31.7-1.3
Food consumed during 24 hour testing period0.20.20.90.3-0.11.0-0.70.70.2-0.60.00.30.2-0.20.00.10.70.1
Times rat made contact with spout0.91.02.9-0.21.10.7-1.01.01.70.11.21.40.20.91.21.20.51.2
Mean time between licks in bursts1.72.44.8-2.01.4-1.81.7-1.70.92.21.00.8-1.81.91.01.0-1.91.1
Mean num. licks in bursts2.02.44.5-2.11.9-1.30.4-0.41.51.81.81.5-0.52.01.81.7-1.31.7
Std. dev. time between licks in bursts0.50.61.3-1.00.6-1.11.0-1.00.11.10.30.2-0.90.80.20.4-1.00.4
Water consumed over 24 hours0.81.03.20.9-0.31.8-1.51.50.3-1.20.10.41.0-0.60.10.01.60.0
Indifference point 0 sec0.91.52.70.9-1.61.3-0.50.5-0.7-1.4-1.5-1.2-0.2-1.6-1.5-1.60.7-1.5
Indifference point AUC2.12.44.62.2-1.41.4-1.41.4-1.9-2.0-1.1-1.01.9-1.9-1.1-1.01.8-1.2
Indifference point function ln k2.13.07.1-2.71.6-1.41.4-1.42.22.11.21.1-2.22.11.21.1-2.11.3
Indifference point function log k2.13.07.1-2.71.6-1.41.4-1.42.22.11.21.1-2.22.11.21.1-2.11.3
Delay discounting total patch changes 0 sec0.81.42.50.8-1.61.0-0.30.3-0.7-1.2-1.5-1.3-0.3-1.6-1.5-1.60.5-1.5
Delay discounting total patch changes 12 sec1.31.73.41.1-1.80.4-0.00.0-1.3-1.0-1.7-1.7-0.1-1.7-1.7-1.70.4-1.8
Delay discounting total patch changes 18 sec1.21.52.71.4-1.41.2-0.70.7-1.6-1.5-1.2-1.10.8-1.6-1.2-1.21.2-1.3
Delay discounting total patch changes 24 sec4.65.810.72.4-3.02.0-1.11.1-2.9-2.7-2.7-2.41.1-3.3-2.7-2.71.8-2.7
Delay discounting total patch changes 6 sec3.04.68.51.8-2.90.8-0.00.0-2.1-1.9-2.8-2.8-0.2-2.9-2.8-2.80.7-2.9
Delay discounting time to switch 0 sec0.20.31.0-0.70.3-0.50.8-0.80.20.70.20.2-1.00.60.10.2-0.80.2
Delay discounting water rate 0 sec0.30.51.00.1-0.9-0.10.4-0.4-0.6-0.2-0.9-1.0-0.5-0.8-0.9-1.0-0.2-1.0
Delay discounting water rate 12 sec0.00.00.1-0.30.2-0.30.1-0.1-0.00.20.20.1-0.20.20.20.1-0.20.2
Delay discounting water rate 18 sec0.10.20.40.30.30.4-0.50.50.6-0.20.30.40.40.10.40.40.40.4
Delay discounting water rate 24 sec2.02.74.91.9-1.92.0-1.31.3-1.2-2.2-1.6-1.30.7-2.2-1.6-1.61.6-1.7
Delay discounting water rate 6 sec0.00.00.1-0.1-0.1-0.30.1-0.1-0.10.1-0.1-0.2-0.3-0.0-0.1-0.2-0.3-0.1
Locomotor activity1.82.94.6-1.72.1-2.00.7-0.72.11.91.91.50.32.11.91.9-1.31.9
Locomotor testing distance0.61.02.5-0.21.3-0.9-0.40.41.60.61.30.91.30.91.21.2-0.01.2
Locomotor testing rearing0.10.20.7-0.30.5-0.80.2-0.20.70.50.40.10.40.40.50.3-0.40.4
Light reinforcement 10.50.92.1-1.00.7-1.41.0-1.01.11.30.50.3-1.01.00.40.6-1.20.5
Light reinforcement 20.10.20.7-0.40.4-0.30.2-0.20.70.60.20.3-0.80.50.30.3-0.50.3
Reaction time number correct2.13.05.20.42.00.5-1.71.71.5-0.02.22.22.21.22.32.11.32.1
Reaction time mean minus median0.40.51.1-1.00.2-0.91.0-1.00.60.90.10.0-1.00.60.10.2-1.00.2
Reaction time mean minus median AUC0.20.20.7-0.4-0.3-0.50.6-0.60.00.3-0.3-0.4-0.80.0-0.3-0.3-0.7-0.3
Reaction time num false alarms0.10.10.50.7-0.2-0.2-0.30.30.2-0.2-0.4-0.40.7-0.5-0.4-0.30.2-0.3
Reaction time num false alarms AUC0.20.31.10.9-0.20.3-0.70.70.1-0.5-0.2-0.21.0-0.5-0.2-0.10.6-0.2
Reaction time trials correct on left2.13.05.20.42.00.5-1.71.71.5-0.02.22.22.21.22.32.11.32.1
Reaction time trials on left2.13.05.50.32.00.4-1.61.61.60.12.32.22.21.32.32.21.22.2
Reaction time mean1.82.44.2-1.71.7-1.81.1-1.11.72.01.61.3-0.62.11.51.6-1.41.6
Reaction time mean AUC1.82.34.3-1.71.6-2.01.3-1.31.52.11.41.0-0.81.91.31.4-1.61.4
Median of all reaction times1.72.34.0-1.51.8-1.81.0-1.01.62.01.61.2-0.52.01.51.6-1.41.6
Reaction time omissions2.43.26.7-2.31.2-2.52.4-2.41.22.60.80.5-2.01.90.80.8-2.40.9
Reaction time false alarm rate0.70.92.10.7-1.2-0.20.3-0.3-0.9-0.5-1.4-1.4-0.1-1.2-1.4-1.3-0.1-1.3
Reaction time premature initiation rate1.41.93.5-0.9-1.0-1.51.8-1.8-1.41.0-1.2-1.5-1.9-0.3-1.2-1.3-1.8-1.3
Reaction time premature initiations0.20.31.0-0.50.3-1.00.6-0.6-0.40.80.2-0.0-0.40.50.30.1-0.90.1
Std. dev. reaction times0.40.51.0-1.00.5-0.90.9-0.90.61.00.40.3-0.80.80.40.4-0.90.5
Reaction time trials completed2.13.05.50.32.00.4-1.61.61.60.12.32.22.21.32.32.21.22.2
Reaction time trials AUC2.02.85.30.32.00.3-1.51.51.50.12.22.12.11.32.32.11.12.1
Social response proportion2.32.54.3-2.11.9-1.30.8-0.81.91.81.61.5-0.92.11.61.7-1.41.7
Social responses0.10.10.1-0.2-0.3-0.00.2-0.2-0.0-0.0-0.3-0.4-0.2-0.3-0.4-0.4-0.2-0.4
Social time5.16.713.5-3.42.4-3.32.4-2.42.23.71.91.5-2.23.21.92.0-3.12.0
Conditioned locomotion0.60.72.4-1.10.2-1.01.1-1.1-0.31.1-0.1-0.1-1.60.7-0.10.0-1.30.0
Cocaine response after cond. corrected2.62.97.9-2.80.6-2.22.4-2.40.02.40.2-0.1-2.21.40.10.1-2.50.2
Cocaine response after cond. not corrected2.93.27.7-2.81.0-2.62.3-2.30.62.60.60.2-1.81.70.60.6-2.60.6
Cocaine response before conditioning0.10.21.30.9-0.0-0.4-0.20.20.2-0.2-0.0-0.21.2-0.2-0.1-0.00.3-0.1
Saline control response0.50.71.6-0.70.9-1.00.2-0.21.31.00.90.60.20.90.90.8-0.60.8
Condit. Reinf. active minus inactive responses0.70.91.7-0.51.2-0.80.0-0.01.30.91.21.10.91.21.01.2-0.31.2
Condit. Reinf. active-inactive response ratio1.51.52.7-1.51.3-1.30.8-0.81.61.61.21.0-0.51.61.01.2-1.21.2
Condit. Reinf. active responses1.52.13.6-0.11.7-0.1-1.11.11.80.41.91.81.91.41.81.90.51.8
Condit. Reinf. inactive responses1.41.75.30.71.10.8-1.71.70.8-0.71.41.42.30.41.41.31.41.3
Condit. Reinf. lever presses0.10.10.2-0.00.3-0.2-0.10.10.50.20.40.30.50.30.30.4-0.00.4
Condit. Reinf. lever reinforcers received1.41.93.50.11.60.1-1.21.21.70.31.81.81.91.21.61.80.71.7
Pavlov. Cond. lever latency0.30.41.1-0.80.6-0.40.5-0.50.80.80.50.5-1.10.80.50.5-0.60.5
Pavlov. Cond. magazine entry latency0.10.10.8-0.6-0.20.20.3-0.30.10.1-0.2-0.1-0.90.1-0.3-0.1-0.3-0.2
Pavlov. Cond. change in total contacts0.40.51.90.00.70.0-0.70.70.4-0.10.90.81.40.40.80.90.50.8
Pavlov. Cond. index score0.20.20.50.5-0.30.7-0.60.6-0.4-0.7-0.2-0.10.7-0.5-0.3-0.10.7-0.2
Pavlov. Cond. latency score0.20.20.60.4-0.20.7-0.70.7-0.3-0.7-0.10.10.7-0.4-0.1-0.00.7-0.1
Pavlov. Cond. lever contacts0.60.81.90.9-1.00.5-0.40.4-1.4-1.0-0.9-0.90.8-1.2-0.9-0.90.7-0.9
Pavlov. Cond. magazine entry number0.40.41.4-0.50.7-1.20.7-0.70.41.00.50.3-0.30.80.60.4-0.80.5
Pavlov. Cond. intertrial magazine entries0.50.62.11.40.20.7-1.11.10.1-0.80.40.31.5-0.30.50.31.10.3
Pavlov. Cond. lever-magazine prob. diff.0.20.30.70.5-0.20.8-0.80.8-0.3-0.7-0.10.10.8-0.4-0.10.00.8-0.1
Pavlov. Cond. response bias0.40.51.10.5-0.90.3-0.10.1-1.1-0.7-0.8-0.80.5-0.9-0.8-0.70.4-0.8
Conditioned reinforcement - actives0.30.30.5-0.20.60.0-0.40.40.40.30.70.70.40.60.70.70.10.6
Conditioned reinforcement - inactives0.00.00.10.1-0.00.2-0.20.2-0.2-0.20.00.00.2-0.10.00.00.30.0
Conditioned locomotion1.92.36.31.50.31.8-2.52.50.4-1.50.70.92.5-0.40.70.72.20.6
Intermittent access intake day 1-15 change1.21.22.11.4-1.01.3-1.01.0-1.4-1.4-0.8-0.71.0-1.3-0.8-0.81.2-0.9
Intermittent access intake escalation0.50.51.00.9-0.60.8-0.70.7-1.0-0.9-0.5-0.40.7-0.8-0.5-0.50.8-0.5
Intermittent access intake escalation 20.30.30.90.60.20.7-1.01.0-0.0-0.50.30.40.9-0.10.30.30.80.3
Intermitt. access day 1 inactive lever presses0.00.00.1-0.30.2-0.30.3-0.3-0.20.20.10.0-0.30.20.10.1-0.30.1
Intermitt. access day 15 inactive lever presses0.40.40.8-0.50.9-0.3-0.10.10.60.50.90.80.20.80.90.9-0.10.9
Intermitt. access escalation Index0.10.10.30.10.20.3-0.50.5-0.2-0.30.40.40.40.10.30.30.40.3
Intermittent access day 1 total infusions2.32.75.2-1.12.3-0.5-0.60.61.50.92.22.10.72.02.32.3-0.02.3
Intermittent access day 15 total infusions0.91.02.60.60.60.9-1.51.5-0.2-0.80.80.91.60.10.90.91.30.8
Intermittent access terminal intake (last 3 days)2.02.24.30.41.50.9-1.91.90.7-0.51.71.82.10.81.71.71.41.7
Intermittent access total infusions1.92.14.00.31.40.8-1.81.80.7-0.51.71.72.00.81.71.71.41.6
Intermittent access day 1 locomotion0.80.91.5-0.11.10.3-0.90.90.7-0.01.21.21.10.81.21.20.61.2
Intermittent access day 15 total locomotion2.42.55.22.1-1.22.0-1.81.8-1.3-2.3-0.9-0.61.9-1.8-0.8-0.82.1-0.9
Intermittent access total locomotion1.92.15.51.6-0.11.8-2.32.3-0.1-1.80.30.52.3-0.80.30.32.20.2
Intermittent access standard deviation0.10.10.70.2-0.30.10.1-0.1-0.8-0.1-0.3-0.3-0.0-0.3-0.3-0.3-0.0-0.3
Cocaine induced anxiety0.70.71.80.60.50.7-1.21.21.4-0.60.70.81.30.10.70.71.00.7
Post-drug Anxiety1.21.33.20.01.20.4-1.11.11.8-0.01.41.41.20.91.41.40.71.4
Baseline Anxiety0.40.41.4-0.3-0.5-0.40.8-0.8-1.20.3-0.6-0.7-0.9-0.2-0.6-0.6-0.7-0.6
Lifetime Intake2.02.23.70.01.70.6-1.61.61.0-0.11.91.91.81.11.91.91.11.8
Incentive Sensitization - Responses1.91.94.91.6-0.21.8-2.22.2-0.0-1.60.20.42.1-0.80.20.22.10.1
Incentive Sensitization - Breakpoint1.91.95.01.5-0.01.7-2.22.20.1-1.50.30.62.2-0.70.30.32.10.2
Progressive ratio test 1 active lever presses1.41.53.70.61.01.0-1.71.7-0.2-0.71.21.31.90.41.21.21.41.2
Progressive ratio test 1 breakpoint1.71.84.30.71.01.1-1.91.9-0.1-0.91.31.42.10.31.31.31.61.2
Progressive ratio test 1 inactive lever presses0.80.81.5-0.21.10.3-0.90.90.70.01.21.21.00.81.21.20.61.2
Progressive ratio test 2 active lever presses1.71.85.11.00.71.3-2.12.10.2-1.01.01.22.30.11.01.01.80.9
Progressive ratio test 2 breakpoint2.02.26.51.40.41.7-2.42.4-0.2-1.40.70.92.5-0.40.70.72.20.6
Progressive ratio test 2 inactive lever presses0.60.71.50.20.70.5-1.11.10.5-0.30.90.91.20.40.90.90.90.8
Total sessions with >9 infusions1.01.12.0-1.11.4-0.70.2-0.21.01.01.31.20.11.41.31.3-0.41.3
Short access day 1 total inactive lever presses2.22.54.72.1-1.22.0-1.81.8-1.0-2.2-0.8-0.62.0-1.8-0.8-0.82.1-0.9
Short access day 10 total inactive lever presses1.21.42.70.7-1.60.20.5-0.5-1.2-0.6-1.6-1.6-0.5-1.4-1.6-1.60.0-1.6
Short access day 1 total infusions0.60.71.80.40.60.6-1.21.20.6-0.40.80.91.30.30.80.81.00.7
Short access day 10 total infusions1.11.32.4-0.51.5-0.1-0.70.71.00.51.51.50.91.21.51.50.31.5
Short access total infusions1.51.73.2-0.51.70.0-0.90.91.10.41.81.81.21.41.81.80.51.7
Short access day 1 locomotion1.11.22.11.4-1.01.3-1.11.1-0.3-1.5-0.8-0.61.2-1.3-0.8-0.81.4-0.8
Short access day 10 total locomotion0.30.30.60.6-0.80.4-0.20.2-0.4-0.6-0.7-0.60.2-0.8-0.7-0.70.4-0.7
Short access total locomotion0.50.50.90.00.80.3-0.80.80.8-0.00.90.90.90.50.90.90.60.9
Compulsive drug intake0.50.51.10.30.50.5-1.01.00.6-0.40.70.71.00.20.60.60.80.6
One hour access (0.3 mA shock)1.01.13.00.70.71.0-1.61.6-0.2-0.70.91.01.70.21.01.01.30.9
One hour access (shock baseline)0.60.81.5-0.11.10.2-0.80.80.40.11.11.10.90.81.21.20.51.2
Number of responses in last shaping day1.11.12.11.4-1.21.2-0.90.9-0.7-1.3-1.0-0.80.9-1.4-1.0-1.01.2-1.0
Context. condit. distance diff. score2.22.75.30.3-2.10.51.0-1.0-1.8-0.7-2.3-2.0-1.9-1.6-2.1-2.3-0.4-2.1
Locomotion velocity, session 11.82.04.51.11.01.3-2.12.10.7-1.21.21.22.10.01.31.31.71.2
Locomotion distance, session 11.21.54.31.50.21.4-1.91.90.2-1.40.50.72.1-0.50.50.61.80.4
Locomotion velocity, session 23.74.410.71.71.02.6-3.33.31.3-1.81.61.92.80.01.61.52.81.5
Locomotion distance, session 21.72.45.81.50.52.0-2.42.40.4-1.61.01.22.3-0.20.91.02.20.9
Locomotion velocity, session 30.30.40.90.7-0.10.7-0.90.9-0.7-0.8-0.00.00.9-0.50.10.10.90.0
Locomotion distance, session 30.30.30.80.20.30.7-0.90.90.3-0.40.40.60.80.00.40.50.80.4
Stereotopy head waving bouts, day 30.10.10.40.00.30.2-0.40.40.4-0.10.50.40.70.20.30.40.40.3
Stereotopy head waving duration, day 30.30.40.70.6-0.80.10.1-0.1-0.8-0.5-0.7-0.80.3-0.9-0.8-0.80.2-0.9
Locomotion velocity, session 72.12.36.41.10.42.0-2.22.2-0.2-1.90.71.02.5-0.40.80.82.30.7
Locomotion distance, session 70.60.81.60.50.51.2-1.31.30.5-0.70.61.00.90.30.70.71.20.7
Stereotopy head waving bouts, day 71.51.73.61.3-1.31.8-1.11.1-1.2-1.9-1.0-0.80.8-1.7-1.0-1.11.5-1.1
Stereotopy head waving duration, day 71.51.83.71.5-1.41.6-1.11.1-1.4-1.9-1.1-1.00.9-1.8-1.1-1.21.5-1.2
Locomotion velocity, session 81.62.03.81.3-1.81.4-0.50.5-1.5-1.7-1.6-1.40.1-2.0-1.6-1.60.9-1.6
Locomotion distance, session 80.71.01.80.9-1.31.3-0.50.5-1.0-1.2-1.2-0.8-0.3-1.2-1.1-1.10.8-1.1
Degree of sensitization distance0.40.41.0-0.40.90.2-0.20.20.70.30.81.0-0.10.90.90.8-0.00.9
Degree of sensitization stereotypy1.41.53.01.1-1.51.3-0.60.6-1.5-1.6-1.3-1.20.4-1.7-1.3-1.31.1-1.3
Condit. Reinf. active minus inactive responses1.21.32.6-0.71.5-0.2-0.40.41.30.51.61.50.61.31.51.6-0.01.6
Condit. Reinf. active-inactive response ratio1.51.62.7-1.71.5-1.10.5-0.51.31.31.51.2-0.31.61.41.4-0.91.5
Condit. Reinf. active responses0.91.13.30.50.90.7-1.31.30.8-0.61.11.11.80.31.11.11.11.1
Condit. Reinf. inactive responses1.82.16.02.3-0.71.6-1.81.8-0.6-1.9-0.4-0.22.4-1.4-0.3-0.32.1-0.4
Incentive salience index mean1.21.52.9-0.91.6-0.2-0.50.51.40.51.61.50.81.31.71.70.01.7
Condit. Reinf. lever presses0.40.51.3-0.20.80.1-0.70.70.8-0.10.70.81.20.41.01.00.50.9
Time in familiar zone, hab. session 10.40.31.7-0.10.50.4-0.60.61.30.00.60.80.40.50.50.50.30.6
Time in novel zone, hab. session 12.12.05.10.9-1.8-0.30.8-0.8-2.3-0.5-1.8-2.0-0.4-1.6-1.8-1.8-0.2-1.9
Total zone transitions, hab. session 10.71.02.01.4-1.10.5-0.40.4-1.2-1.0-1.0-0.91.0-1.3-1.0-0.90.8-1.0
Total locomotion distance, hab. session 12.23.15.81.9-2.20.7-0.30.3-2.2-1.7-2.1-2.10.9-2.4-2.1-2.01.0-2.1
Locomotion velocity, hab. session 12.02.95.41.9-2.10.8-0.40.4-2.1-1.7-2.0-1.91.1-2.3-1.9-1.91.1-2.0
Time in familiar zone, hab. session 21.11.13.4-1.20.5-1.81.6-1.60.31.50.1-0.2-0.90.80.20.2-1.50.2
Time in novel zone, hab. session 21.61.62.81.5-1.41.6-1.11.1-1.2-1.7-1.0-0.80.6-1.6-1.1-1.21.3-1.1
Total zone transitions, hab. session 20.40.51.71.1-0.10.8-1.01.0-0.4-0.8-0.00.11.3-0.50.00.11.10.0
Total locomotion distance, hab. session 20.30.41.21.0-0.50.4-0.70.7-0.3-0.7-0.4-0.31.1-0.7-0.4-0.30.8-0.4
Locomotion velocity, hab. session 20.40.62.01.2-0.30.7-1.01.0-0.1-0.8-0.2-0.11.4-0.6-0.2-0.11.0-0.2
Novel to familiar place preference ratio4.54.88.90.4-2.8-0.41.6-1.6-2.5-0.5-2.9-3.0-1.6-2.2-3.0-3.0-0.9-2.9
Novelty place preference5.96.111.40.6-3.2-0.31.7-1.7-2.9-0.7-3.3-3.4-1.7-2.6-3.4-3.4-0.8-3.3
Time in novel zone, NPP test6.46.712.60.6-3.4-0.21.7-1.7-3.1-0.8-3.4-3.5-1.8-2.7-3.5-3.6-0.8-3.5
Total zone transitions, NPP test1.31.95.31.50.81.2-2.02.00.7-1.01.11.32.30.11.11.21.81.1
Total locomotion distance, NPP test0.60.83.11.10.40.7-1.31.30.4-0.60.50.71.8-0.00.60.61.20.6
Locomotion velocity, NPP test0.81.14.21.20.70.6-1.41.40.5-0.50.81.02.10.20.90.91.30.8
Pavlov. Cond. lever latency0.91.12.40.1-1.2-0.61.0-1.0-1.60.2-1.2-1.4-0.9-0.8-1.4-1.3-0.7-1.3
Pavlov. Cond. magazine entry latency0.30.41.20.9-0.21.1-0.90.9-0.2-1.0-0.20.00.4-0.5-0.0-0.10.9-0.1
Pavlov. Cond. change in total contacts0.30.31.0-0.30.70.1-0.20.21.00.10.60.60.20.50.70.70.10.7
Pavlov. Cond. index score1.21.53.61.20.41.8-1.91.90.7-1.40.60.91.5-0.20.80.71.80.7
Pavlov. Cond. latency score1.11.43.00.80.81.5-1.71.71.0-1.10.91.21.40.11.11.11.51.0
Pavlov. Cond. lever contacts1.31.52.40.41.11.2-1.61.61.5-0.71.11.51.30.51.41.31.21.3
Pavlov. Cond. magazine entry number1.31.65.1-1.50.5-2.31.9-1.90.22.00.3-0.1-0.91.10.10.2-1.90.2
Pavlov. Cond. intertrial magazine entries0.91.12.7-1.40.8-1.51.2-1.20.81.60.70.4-0.91.20.50.6-1.40.6
Pavlov. Cond. lever-magazine prob. diff.1.11.43.31.20.31.8-1.81.80.5-1.50.40.81.4-0.40.60.61.80.5
Pavlov. Cond. response bias1.31.65.01.5-0.32.2-1.91.90.2-1.9-0.20.31.1-0.90.00.01.9-0.0
Bone: apparent density2.43.97.41.4-2.71.00.4-0.4-2.3-1.6-2.6-2.5-0.5-2.5-2.6-2.60.5-2.7
Bone surface0.10.20.30.2-0.60.10.2-0.2-0.5-0.2-0.5-0.5-0.1-0.5-0.6-0.50.1-0.6
Bone volume0.30.50.90.2-0.90.30.4-0.4-0.8-0.4-0.8-0.8-0.5-0.7-0.9-0.90.0-0.9
Bone: connectivity density1.42.13.91.3-2.00.8-0.00.0-1.8-1.3-1.7-1.70.1-1.9-1.9-1.80.7-1.9
Bone: cortical apparent density0.10.10.50.3-0.30.7-0.20.20.2-0.2-0.20.0-0.4-0.2-0.3-0.20.3-0.2
Bone: cortical area0.20.20.8-0.3-0.2-0.40.8-0.8-0.90.4-0.3-0.4-0.6-0.1-0.3-0.4-0.4-0.3
Bone: cortical porosity0.70.73.6-0.5-0.0-1.91.2-1.2-0.91.1-0.4-0.80.10.1-0.3-0.3-1.2-0.3
Bone: cortical porosity0.70.83.6-0.5-0.1-1.91.3-1.3-0.91.0-0.4-0.80.20.0-0.4-0.3-1.2-0.4
Bone: cortical thickness0.71.23.1-0.9-0.4-1.51.8-1.8-1.41.1-0.6-0.9-1.20.0-0.6-0.7-1.3-0.6
Bone: cortical thickness0.80.92.41.30.21.3-1.41.4-0.3-1.10.40.51.5-0.40.40.41.50.4
Bone: cortical tissue density0.10.10.60.4-0.40.8-0.30.30.3-0.3-0.20.0-0.4-0.2-0.3-0.20.4-0.3
Bone: elastic displacement0.70.82.0-1.20.2-1.21.2-1.2-0.51.1-0.1-0.2-1.30.6-0.0-0.1-1.40.0
Bone: elastic work1.21.64.3-1.70.9-1.71.3-1.30.32.10.60.4-1.51.40.60.6-1.90.7
Bone: endosteal estimation0.71.53.71.10.51.7-1.91.91.0-1.10.91.11.40.00.80.81.60.8
Bone: endosteal perimeter0.30.71.10.10.90.5-0.90.90.9-0.21.01.10.90.61.01.00.71.0
Bone: final force0.20.31.20.70.20.4-0.80.8-0.1-0.30.30.31.1-0.10.30.30.70.3
Bone: final moment0.00.10.30.50.00.2-0.40.4-0.2-0.10.00.00.6-0.20.00.10.30.0
Bone: marrow area0.71.53.91.20.41.8-2.02.00.9-1.20.71.01.3-0.10.70.71.70.7
Bone: maximum diameter0.00.10.30.1-0.20.10.3-0.3-0.6-0.0-0.2-0.2-0.2-0.2-0.2-0.30.0-0.2
Bone: maximum force0.10.20.4-0.30.5-0.30.1-0.10.30.70.50.50.00.50.50.5-0.20.5
Bone: maximum moment0.20.30.8-0.60.5-0.60.4-0.40.40.90.40.3-0.50.60.40.4-0.60.4
Bone: minimum diameter0.30.61.1-1.00.9-0.60.6-0.60.70.90.80.7-0.51.00.80.8-0.50.8
Bone: periosteal estimation0.20.30.90.60.30.9-0.90.90.1-0.50.40.60.6-0.00.40.40.90.4
Bone: periosteal perimeter0.20.30.9-0.70.5-1.00.8-0.8-0.10.90.30.1-0.20.60.30.3-0.70.3
Bone: post-yield work1.01.33.0-1.01.4-0.1-0.10.11.70.91.51.5-0.21.51.41.4-0.11.5
Bone: stiffness0.10.20.5-0.60.3-0.60.6-0.60.10.70.20.1-0.30.40.20.2-0.40.2
Bone: tissue strength3.83.79.2-2.50.7-2.92.6-2.60.72.80.1-0.3-2.51.50.20.2-3.00.3
Bone: trabecular number4.16.311.92.1-3.41.00.3-0.3-2.8-2.1-3.3-3.20.1-3.3-3.3-3.30.9-3.4
Bone: trabecular spacing2.12.75.2-1.22.3-0.3-0.50.51.41.12.22.20.32.12.32.2-0.22.3
Bone: trabecular thickness0.30.40.70.3-0.70.8-0.00.0-0.8-0.7-0.6-0.5-0.9-0.6-0.6-0.80.3-0.7
Bone: trabecular tissue density1.72.34.9-2.21.2-1.91.7-1.70.72.20.80.6-1.91.80.90.9-2.01.0
Breakpoint value in progressive ratio session3.53.97.62.4-2.12.1-1.41.4-2.2-2.8-1.9-1.71.1-2.7-1.7-1.72.0-1.8
Distance traveled before self-admin1.71.93.31.2-1.80.80.1-0.1-1.7-1.2-1.8-1.7-0.2-1.8-1.7-1.70.6-1.7
Distance traveled after self-admin1.01.12.21.4-1.01.2-1.01.0-1.1-1.5-0.8-0.70.9-1.3-0.8-0.81.3-0.8
Delta time in closed arm before/after self-admin0.20.20.40.4-0.60.20.0-0.0-0.1-0.2-0.5-0.50.1-0.5-0.6-0.60.2-0.6
Delta time in open arm before/after self-admin0.70.71.3-0.91.0-0.70.3-0.31.01.01.00.8-0.51.20.90.9-0.70.9
Diff in mean of infusions in LGA sessions0.30.30.70.3-0.60.30.2-0.2-0.8-0.6-0.8-0.7-0.4-0.8-0.5-0.50.2-0.5
Extinction: sum of active levers before priming0.10.10.30.10.20.3-0.40.4-0.2-0.20.20.30.50.00.30.20.40.3
Active lever presses in extinction session 60.20.20.40.6-0.30.6-0.50.5-0.3-0.7-0.3-0.20.4-0.5-0.2-0.20.6-0.2
Delta distance traveled before/after self-admin0.90.91.6-0.11.20.2-0.90.91.10.11.31.30.90.91.21.30.41.2
Delta ambulatory time before/after self-admin0.70.71.10.10.90.4-1.01.00.8-0.21.01.11.00.61.01.00.61.0
Time in closed arm before self-admin0.10.21.4-0.1-0.2-0.10.2-0.2-1.2-0.2-0.3-0.4-0.4-0.3-0.2-0.2-0.2-0.3
Time in closed arm after self-admin0.10.10.4-0.3-0.1-0.40.5-0.5-0.50.2-0.2-0.3-0.6-0.0-0.2-0.2-0.5-0.2
Time in open arm before self-admin0.70.71.41.0-1.20.7-0.20.2-0.7-0.7-1.1-0.90.4-1.1-1.1-1.10.6-1.1
Time in open arm after self-admin0.00.00.2-0.20.1-0.20.2-0.20.40.30.10.1-0.20.20.00.0-0.30.1
Sum of active levers in priming session hrs 5-61.81.82.90.01.50.6-1.51.51.5-0.21.71.71.41.01.71.61.01.6
Time to tail flick, vehicle, before self-admin1.51.53.0-1.71.2-1.51.3-1.30.71.70.90.7-1.21.50.90.9-1.51.0
Time to tail flick, vehicle, after self-admin1.41.53.2-1.31.5-0.90.3-0.31.81.31.41.3-0.51.61.41.4-0.81.4
Time to tail flick, test, before self-admin2.01.93.6-0.5-1.2-0.91.8-1.8-1.50.5-1.5-1.6-1.9-0.7-1.5-1.5-1.4-1.4
Time to tail flick, test, after self-admin2.12.23.8-0.0-1.7-0.41.5-1.5-1.7-0.1-1.8-1.9-1.6-1.3-1.9-1.9-0.9-1.8
Delta time to tail flick, vehicle, before/after SA0.80.81.4-0.91.1-0.60.1-0.11.20.91.01.0-0.21.21.01.0-0.51.0
Delta time to tail flick, test, before/after SA0.70.61.30.5-1.10.40.2-0.2-0.7-0.6-1.0-1.0-0.2-1.0-1.1-1.10.2-1.1
Ambulatory time before self-admin1.41.53.41.0-1.60.60.1-0.1-1.9-1.0-1.6-1.50.0-1.6-1.5-1.40.5-1.5
Ambulatory time after self-admin0.70.81.51.1-0.81.0-0.80.8-1.0-1.2-0.6-0.50.8-1.1-0.6-0.61.0-0.7
Total heroin consumption4.45.39.62.4-2.91.8-0.70.7-2.9-2.6-2.6-2.40.8-3.1-2.6-2.61.7-2.7
Area under the delay curve0.80.81.5-0.1-1.0-0.31.1-1.1-0.4-0.0-1.1-1.2-1.2-0.7-1.1-1.2-0.7-1.1
Delay disc. indifference point, 0s delay0.40.41.90.10.50.4-0.80.81.4-0.20.60.60.70.20.50.50.60.6
Delay disc. indifference point, 16s delay0.90.91.70.3-1.3-0.00.9-0.9-0.5-0.4-1.3-1.3-0.9-1.0-1.3-1.3-0.4-1.3
Delay disc. indifference point, 2s delay0.40.41.20.1-0.7-0.10.7-0.70.1-0.1-0.8-0.8-0.8-0.5-0.8-1.1-0.4-0.8
Delay disc. indifference point, 24s delay0.80.81.40.1-1.20.00.9-0.9-0.8-0.3-1.1-1.1-1.1-0.8-1.1-1.2-0.5-1.2
Delay disc. indifference point, 4s delay0.10.10.40.3-0.40.1-0.00.0-0.1-0.3-0.4-0.50.1-0.5-0.5-0.60.2-0.4
Delay disc. indifference point, 8s delay0.50.51.5-0.7-0.3-0.61.1-1.10.40.5-0.4-0.5-1.20.1-0.4-0.4-1.0-0.4
Delay discount exponential model param0.91.01.70.11.10.4-1.21.20.50.01.21.31.30.71.21.30.81.2
Delay discount hyperbolic model param0.70.71.30.20.90.4-1.11.10.3-0.11.01.11.10.61.01.10.71.0
Fecal boli incidents, locomotor time 11.61.73.6-1.91.5-1.10.6-0.61.51.51.31.2-1.01.81.31.1-1.21.3
Change in fecal boli incidents, locomotor task1.11.01.91.4-1.01.1-0.90.9-0.7-1.3-0.8-0.71.0-1.3-0.9-0.91.1-0.8
Time >=10cm from walls, locomotor time 10.00.00.1-0.30.2-0.20.1-0.10.10.20.20.2-0.10.30.30.3-0.20.2
Bouts of movement, locomotor time 10.40.40.9-0.80.6-0.90.8-0.80.00.90.20.1-0.80.70.30.3-0.90.4
Total resting periods, locomotor time 11.01.12.5-1.40.7-1.41.4-1.40.21.40.30.1-1.41.00.20.3-1.60.5
Rest time, locomotor task time 11.01.05.0-0.91.2-0.60.0-0.02.21.01.11.1-0.11.30.91.0-0.51.1
Distance moved, locomotor task time 11.61.74.91.5-1.31.4-1.01.0-2.2-1.7-0.9-0.81.1-1.6-0.9-1.01.5-1.1
Vertical activity count, locomotor time 11.31.34.81.2-1.41.0-0.40.4-2.2-1.3-1.2-1.00.4-1.5-1.0-1.00.9-1.2
Time >=10cm from walls, locomotor time 20.10.10.3-0.20.4-0.20.1-0.10.50.40.20.3-0.10.40.30.2-0.20.3
Bouts of movement, locomotor time 21.41.53.9-1.2-0.1-1.62.0-2.0-1.11.2-0.5-0.8-1.80.3-0.7-0.3-1.9-0.4
Total resting periods, locomotor time 21.41.53.8-1.30.1-1.72.0-2.0-0.71.4-0.2-0.6-1.70.6-0.4-0.1-1.9-0.1
Rest time, locomotor task time 20.10.20.3-0.4-0.1-0.50.6-0.60.50.5-0.0-0.1-0.50.2-0.1-0.2-0.6-0.1
Distance moved, locomotor task time 20.80.92.91.20.01.0-1.41.4-0.3-1.00.30.41.7-0.50.30.21.50.2
Vertical activity count, locomotor time 21.01.12.70.80.61.0-1.61.60.9-0.70.81.01.60.20.91.01.30.8
Weight adjusted by age0.70.81.7-0.71.1-0.4-0.10.10.80.81.31.20.31.21.11.3-0.21.1
Seeking ratio, delayed vs. immediate footshock0.50.50.90.8-0.90.3-0.20.2-0.9-0.7-0.9-0.80.4-1.0-0.9-0.90.4-0.9
Locomotion in novel chamber0.60.82.40.80.20.9-1.31.30.9-0.70.60.71.5-0.00.40.61.30.4
Locomotion in novel chamber post-restriction0.20.20.5-0.2-0.6-0.50.6-0.6-0.30.3-0.4-0.5-0.5-0.1-0.7-0.3-0.6-0.6
Progressive ratio0.10.10.30.10.4-0.1-0.30.30.40.10.30.30.50.20.40.30.10.4
Food seeking constrained by brief footshock0.30.31.2-0.5-0.2-0.60.8-0.80.50.4-0.5-0.5-1.1-0.0-0.2-0.5-0.6-0.3
Seeking ratio, punishment vs. effort0.40.41.2-0.1-0.7-0.10.7-0.7-0.4-0.1-0.8-0.8-1.1-0.5-0.8-0.8-0.4-0.8
Run reversals in cocaine runway, females0.60.61.90.8-0.20.9-0.90.9-1.4-1.00.00.11.2-0.5-0.10.11.1-0.0
Run reversals in cocaine runway, males0.50.51.50.30.40.6-0.90.91.2-0.30.60.70.70.20.60.60.60.6
Latency to leave start box in cocaine runway0.40.40.8-0.90.5-0.70.8-0.80.00.80.40.3-0.60.70.30.4-0.90.4
Latency to leave start box in cocaine runway, F0.30.40.9-1.00.4-0.70.7-0.7-0.10.80.40.3-0.50.70.30.5-0.80.4
Latency to leave start box in cocaine runway, M0.30.30.8-0.50.1-0.70.9-0.9-0.20.6-0.1-0.1-0.80.4-0.1-0.1-0.9-0.0
Cd content in liver0.80.91.8-0.31.4-0.70.0-0.00.50.81.31.10.41.21.31.3-0.31.3
Co content in liver0.30.40.80.40.60.2-0.70.70.3-0.30.70.70.90.30.70.70.60.7
Cu content in liver0.30.40.8-0.90.8-0.40.3-0.30.30.60.60.6-0.60.80.70.7-0.60.7
Fe content in liver1.21.53.1-1.51.2-1.71.2-1.21.11.71.00.7-0.51.50.90.9-1.41.0
K content in liver0.80.81.3-0.3-1.0-0.31.0-1.0-0.70.1-1.1-1.1-1.1-0.6-1.1-1.1-0.6-1.1
Mg content in liver1.11.23.7-1.1-0.5-1.11.6-1.6-0.51.0-0.8-0.9-1.90.1-0.7-0.7-1.5-0.7
Mn content in liver1.11.33.4-1.5-0.3-1.31.8-1.8-0.11.2-0.6-0.7-1.70.3-0.5-0.5-1.5-0.5
Na content in liver1.01.12.01.2-1.41.0-0.40.4-0.3-1.1-1.2-1.00.1-1.4-1.2-1.20.8-1.3
Rb content in liver0.50.61.8-0.9-0.2-1.41.3-1.3-0.50.9-0.4-0.7-0.40.1-0.4-0.4-1.0-0.4
Se content in liver0.70.81.7-0.01.1-0.3-0.30.31.30.51.21.10.90.91.21.20.21.1
Sr content in liver0.90.82.11.5-0.41.1-1.31.3-0.1-1.3-0.1-0.01.2-0.8-0.1-0.11.3-0.2
Zn content in liver0.40.42.3-0.7-0.0-0.50.9-0.9-0.10.7-0.2-0.2-1.50.3-0.2-0.2-1.1-0.1