# | tissue | modality | RNA phenotype | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | LASSO R2 | eQTL P | BLUP P | ENET P | LASSO P |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | BLA | alternative TSS | ENSRNOT00000015195 | 0.2921 | 0.1280 | 1.6e-11 | 0.151 | 0.089 | 0.132 | 0.077 | 1.9e-08 | 1.8e-05 | 1.5e-07 | 6.3e-05 |
2 | BLA | alternative TSS | ENSRNOT00000100768 | 0.3051 | 0.1258 | 3.2e-13 | 0.206 | 0.066 | 0.171 | 0.187 | 2.9e-11 | 2.1e-04 | 1.8e-09 | 2.9e-10 |
3 | BLA | alternative TSS | ENSRNOT00000015195 | 0.3081 | 0.1332 | 6.3e-12 | 0.160 | 0.092 | 0.148 | 0.150 | 6.4e-09 | 1.3e-05 | 2.7e-08 | 2.1e-08 |
4 | BLA | alternative TSS | ENSRNOT00000100768 | 0.3133 | 0.1284 | 2.0e-13 | 0.209 | 0.064 | 0.171 | 0.183 | 2.1e-11 | 2.5e-04 | 1.8e-09 | 4.6e-10 |
5 | BLA | gene expression | ENSRNOG00000011400 | 0.1966 | 0.0944 | 4.0e-07 | 0.085 | 0.058 | 0.073 | 0.073 | 2.6e-05 | 5.0e-04 | 9.4e-05 | 9.8e-05 |
6 | BLA | isoform ratio | ENSRNOT00000015195 | 0.0890 | 0.0550 | 1.2e-03 | 0.042 | 0.026 | 0.038 | 0.041 | 2.6e-03 | 1.4e-02 | 4.2e-03 | 3.1e-03 |
7 | BLA | isoform ratio | ENSRNOT00000068507 | 0.0710 | 0.0460 | 2.1e-03 | -0.002 | 0.006 | 0.020 | 0.010 | 4.1e-01 | 1.4e-01 | 3.0e-02 | 9.0e-02 |
8 | BLA | isoform ratio | ENSRNOT00000100768 | 0.1600 | 0.0870 | 9.2e-07 | 0.048 | 0.025 | 0.081 | 0.084 | 1.4e-03 | 1.7e-02 | 4.3e-05 | 2.9e-05 |
9 | BLA | intron excision ratio | chr2:87483682:87549405 | 0.0520 | 0.0370 | 9.9e-03 | 0.032 | 0.018 | 0.028 | 0.019 | 8.0e-03 | 3.7e-02 | 1.2e-02 | 3.4e-02 |
10 | BLA | mRNA stability | ENSRNOG00000011400 | 0.2900 | 0.1300 | 8.0e-11 | 0.083 | 0.148 | 0.149 | 0.162 | 3.3e-05 | 2.6e-08 | 2.2e-08 | 5.3e-09 |
11 | Brain | alternative TSS | ENSRNOT00000015195 | 0.1981 | 0.0950 | 2.6e-10 | 0.059 | 0.067 | 0.059 | 0.069 | 3.5e-06 | 7.8e-07 | 3.8e-06 | 5.7e-07 |
12 | Brain | alternative TSS | ENSRNOT00000100768 | 0.2329 | 0.1057 | 6.2e-13 | 0.082 | 0.074 | 0.076 | 0.081 | 4.7e-08 | 2.0e-07 | 1.6e-07 | 5.8e-08 |
13 | Brain | alternative TSS | ENSRNOT00000015195 | 0.1396 | 0.0712 | 1.4e-07 | 0.040 | 0.046 | 0.038 | 0.044 | 1.1e-04 | 4.5e-05 | 1.8e-04 | 6.4e-05 |
14 | Brain | alternative TSS | ENSRNOT00000100768 | 0.2025 | 0.1000 | 1.8e-10 | 0.077 | 0.060 | 0.071 | 0.058 | 1.2e-07 | 3.0e-06 | 3.7e-07 | 4.2e-06 |
15 | Brain | gene expression | ENSRNOG00000011400 | 0.4500 | 0.1200 | 0.0e+00 | 0.249 | 0.251 | 0.268 | 0.262 | 5.7e-23 | 3.3e-23 | 7.8e-25 | 3.1e-24 |
16 | Brain | isoform ratio | ENSRNOT00000068507 | 0.0425 | 0.0311 | 8.7e-03 | 0.001 | 0.003 | -0.002 | 0.000 | 2.8e-01 | 1.4e-01 | 6.6e-01 | 3.2e-01 |
17 | Brain | isoform ratio | ENSRNOT00000100768 | 0.0593 | 0.0420 | 3.3e-03 | 0.024 | 0.009 | 0.013 | 0.004 | 2.7e-03 | 4.5e-02 | 2.2e-02 | 1.2e-01 |
18 | Brain | intron excision ratio | chr2:87631467:87663759 | 0.0602 | 0.0379 | 1.5e-03 | 0.022 | 0.019 | 0.017 | 0.016 | 3.7e-03 | 6.9e-03 | 9.7e-03 | 1.0e-02 |
19 | Brain | mRNA stability | ENSRNOG00000011400 | 0.3592 | 0.1695 | 1.2e-15 | 0.045 | 0.091 | 0.081 | 0.077 | 5.2e-05 | 8.6e-09 | 6.1e-08 | 1.2e-07 |
20 | IL | alternative TSS | ENSRNOT00000100768 | 0.2540 | 0.1370 | 3.8e-03 | 0.043 | 0.000 | 0.013 | 0.034 | 3.4e-02 | 3.2e-01 | 1.5e-01 | 5.3e-02 |
21 | IL | intron excision ratio | chr2:87539239:87549405 | 0.1650 | 0.1050 | 9.6e-03 | 0.077 | 0.009 | 0.032 | 0.065 | 6.6e-03 | 1.9e-01 | 5.8e-02 | 1.2e-02 |
22 | LHb | alternative TSS | ENSRNOT00000015195 | 0.6000 | 0.1530 | 3.6e-08 | 0.203 | 0.187 | 0.223 | 0.212 | 1.5e-05 | 3.3e-05 | 5.1e-06 | 9.2e-06 |
23 | LHb | alternative TSS | ENSRNOT00000100768 | 0.6040 | 0.1440 | 1.6e-09 | 0.158 | 0.206 | 0.270 | 0.173 | 1.4e-04 | 1.2e-05 | 4.0e-07 | 6.6e-05 |
24 | LHb | alternative TSS | ENSRNOT00000015195 | 0.5760 | 0.1480 | 4.0e-08 | 0.160 | 0.190 | 0.200 | 0.193 | 1.2e-04 | 2.8e-05 | 1.7e-05 | 2.4e-05 |
25 | LHb | alternative TSS | ENSRNOT00000100768 | 0.5230 | 0.1540 | 1.5e-07 | 0.138 | 0.160 | 0.218 | 0.153 | 3.8e-04 | 1.3e-04 | 6.6e-06 | 1.8e-04 |
26 | LHb | gene expression | ENSRNOG00000011400 | 0.7326 | 0.1646 | 1.4e-06 | 0.126 | 0.059 | 0.086 | 0.084 | 6.6e-04 | 1.6e-02 | 4.5e-03 | 5.1e-03 |
27 | LHb | intron excision ratio | chr2:87483682:87539067 | 0.3010 | 0.1490 | 6.8e-04 | 0.027 | 0.004 | 0.007 | 0.013 | 7.7e-02 | 2.5e-01 | 2.2e-01 | 1.5e-01 |
28 | LHb | mRNA stability | ENSRNOG00000011400 | 0.4080 | 0.1660 | 3.6e-05 | 0.105 | 0.132 | 0.149 | 0.103 | 1.9e-03 | 5.0e-04 | 2.2e-04 | 2.1e-03 |
29 | NAcc | alternative polyA | ENSRNOT00000015195 | 0.0899 | 0.0560 | 2.2e-03 | 0.010 | 0.011 | 0.016 | 0.009 | 5.9e-02 | 4.6e-02 | 2.1e-02 | 6.8e-02 |
30 | NAcc | alternative TSS | ENSRNOT00000015195 | 0.1040 | 0.0570 | 1.1e-06 | 0.076 | 0.079 | 0.065 | 0.072 | 2.7e-06 | 1.8e-06 | 1.5e-05 | 4.8e-06 |
31 | NAcc | alternative TSS | ENSRNOT00000100768 | 0.1700 | 0.0780 | 2.9e-11 | 0.127 | 0.108 | 0.143 | 0.081 | 1.1e-09 | 2.0e-08 | 9.2e-11 | 1.2e-06 |
32 | NAcc | alternative TSS | ENSRNOT00000015195 | 0.1020 | 0.0570 | 1.5e-06 | 0.068 | 0.083 | 0.071 | 0.076 | 8.7e-06 | 9.4e-07 | 6.0e-06 | 2.5e-06 |
33 | NAcc | alternative TSS | ENSRNOT00000068507 | 0.0610 | 0.0430 | 7.0e-03 | 0.009 | 0.000 | 0.005 | 0.003 | 6.3e-02 | 3.5e-01 | 1.4e-01 | 1.7e-01 |
34 | NAcc | alternative TSS | ENSRNOT00000100768 | 0.1680 | 0.0780 | 5.4e-11 | 0.126 | 0.106 | 0.121 | 0.068 | 1.2e-09 | 2.7e-08 | 2.8e-09 | 9.1e-06 |
35 | NAcc | gene expression | ENSRNOG00000011400 | 0.3600 | 0.1300 | 0.0e+00 | 0.127 | 0.191 | 0.198 | 0.212 | 1.1e-09 | 3.4e-14 | 1.1e-14 | 1.0e-15 |
36 | NAcc | isoform ratio | ENSRNOT00000068507 | 0.1028 | 0.0565 | 7.1e-06 | 0.038 | 0.031 | 0.028 | 0.034 | 7.4e-04 | 2.1e-03 | 3.2e-03 | 1.3e-03 |
37 | NAcc | isoform ratio | ENSRNOT00000100768 | 0.1095 | 0.0587 | 2.3e-06 | 0.055 | 0.038 | 0.041 | 0.041 | 6.0e-05 | 8.1e-04 | 4.6e-04 | 4.6e-04 |
38 | NAcc | intron excision ratio | chr2:87539239:87549405 | 0.0491 | 0.0342 | 4.4e-03 | 0.036 | 0.000 | 0.010 | -0.002 | 1.0e-03 | 3.1e-01 | 5.3e-02 | 4.6e-01 |
39 | NAcc | mRNA stability | ENSRNOG00000011400 | 0.1285 | 0.0685 | 1.4e-07 | 0.074 | 0.050 | 0.065 | 0.072 | 3.7e-06 | 1.3e-04 | 1.3e-05 | 4.9e-06 |
40 | OFC | alternative TSS | ENSRNOT00000015195 | 0.1950 | 0.1150 | 6.0e-03 | 0.006 | 0.008 | -0.012 | -0.009 | 2.3e-01 | 2.0e-01 | 7.9e-01 | 5.7e-01 |
41 | OFC | alternative TSS | ENSRNOT00000100768 | 0.3200 | 0.1420 | 1.1e-04 | 0.121 | 0.104 | 0.049 | 0.061 | 8.7e-04 | 1.9e-03 | 2.6e-02 | 1.5e-02 |
42 | OFC | alternative TSS | ENSRNOT00000100768 | 0.3310 | 0.1470 | 1.3e-04 | 0.109 | 0.111 | 0.114 | 0.087 | 1.5e-03 | 1.4e-03 | 1.2e-03 | 4.3e-03 |
43 | OFC | gene expression | ENSRNOG00000011400 | 0.6020 | 0.1823 | 2.9e-08 | 0.166 | 0.134 | 0.301 | 0.243 | 9.4e-05 | 4.5e-04 | 6.9e-08 | 1.8e-06 |
44 | OFC | intron excision ratio | chr2:87539239:87549405 | 0.3395 | 0.1560 | 1.6e-04 | 0.131 | 0.054 | 0.131 | 0.174 | 5.3e-04 | 2.1e-02 | 5.2e-04 | 6.4e-05 |
45 | OFC | intron excision ratio | chr2:87663834:87750876 | 0.2351 | 0.1297 | 5.1e-03 | 0.064 | 0.004 | 0.027 | 0.029 | 1.3e-02 | 2.5e-01 | 7.6e-02 | 6.9e-02 |
46 | PL | alternative TSS | ENSRNOT00000015195 | 0.1600 | 0.0770 | 6.0e-09 | 0.094 | 0.038 | 0.091 | 0.002 | 1.2e-07 | 6.8e-04 | 2.0e-07 | 2.1e-01 |
47 | PL | alternative TSS | ENSRNOT00000100768 | 0.2000 | 0.0880 | 1.1e-12 | 0.131 | 0.067 | 0.126 | 0.026 | 3.8e-10 | 7.7e-06 | 7.7e-10 | 4.4e-03 |
48 | PL | alternative TSS | ENSRNOT00000015195 | 0.1200 | 0.0640 | 9.5e-07 | 0.060 | 0.025 | 0.064 | -0.001 | 2.3e-05 | 4.8e-03 | 1.2e-05 | 3.7e-01 |
49 | PL | alternative TSS | ENSRNOT00000100768 | 0.1900 | 0.0830 | 6.2e-12 | 0.127 | 0.060 | 0.122 | 0.046 | 6.7e-10 | 2.6e-05 | 1.7e-09 | 1.9e-04 |
50 | PL | gene expression | ENSRNOG00000011400 | 0.3913 | 0.1595 | 0.0e+00 | 0.167 | 0.129 | 0.164 | 0.165 | 9.8e-13 | 4.9e-10 | 1.6e-12 | 1.4e-12 |
51 | PL | isoform ratio | ENSRNOT00000068507 | 0.0880 | 0.0540 | 2.4e-05 | 0.039 | 0.014 | 0.034 | 0.032 | 5.5e-04 | 2.6e-02 | 1.3e-03 | 1.8e-03 |
52 | PL | isoform ratio | ENSRNOT00000100768 | 0.0990 | 0.0550 | 4.7e-06 | 0.030 | 0.029 | 0.051 | 0.024 | 2.4e-03 | 2.6e-03 | 9.7e-05 | 5.7e-03 |
53 | PL | intron excision ratio | chr2:87483682:87539067 | 0.1449 | 0.0787 | 4.0e-08 | 0.064 | 0.046 | 0.060 | 0.067 | 1.3e-05 | 1.9e-04 | 2.6e-05 | 8.8e-06 |
54 | PL | intron excision ratio | chr2:87539239:87549405 | 0.0974 | 0.0675 | 4.7e-05 | 0.038 | 0.030 | 0.028 | 0.034 | 7.1e-04 | 2.2e-03 | 2.9e-03 | 1.2e-03 |
55 | PL | intron excision ratio | chr2:87663834:87750876 | 0.0542 | 0.0365 | 4.1e-03 | 0.049 | -0.001 | 0.034 | 0.045 | 1.2e-04 | 3.6e-01 | 1.2e-03 | 2.2e-04 |
56 | PL | mRNA stability | ENSRNOG00000011400 | 0.1872 | 0.0882 | 3.1e-11 | 0.060 | 0.058 | 0.095 | 0.040 | 2.4e-05 | 3.0e-05 | 1.0e-07 | 5.0e-04 |
All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method.
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 |
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Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bone surface | 6.9 | 12.2 | 19.6 | -4.0 | 4.1 | -4.1 | 4.1 | 3.1 | -4.1 | -0.1 | 4.1 | -3.1 | -3.0 | -3.5 | 3.8 | -3.5 | 4.0 | 2.3 | -4.0 | 4.0 | 1.8 | -3.8 | 3.9 | -2.9 | -2.9 | 3.4 | -3.0 | 3.2 | -1.2 | 4.0 | -3.6 | -1.4 | -3.4 | 4.4 | -3.5 | -3.2 | 4.0 | 0.3 | -3.9 | 4.0 | -3.9 | -2.9 | -4.1 | 4.0 | 3.8 | 3.2 | -4.0 | -1.9 | -3.5 | 4.0 | -4.1 | 3.8 | 3.1 | -3.0 | 3.9 | 3.4 | -4.0 | -3.2 | -3.6 |
Bone volume | 6.9 | 11.7 | 20.9 | -3.9 | 3.9 | -3.9 | 3.9 | 3.1 | -3.9 | 0.2 | 3.9 | -3.3 | -3.3 | -3.4 | 3.7 | -3.5 | 3.9 | 2.2 | -3.9 | 3.9 | 1.5 | -4.0 | 3.8 | -3.1 | -2.5 | 3.1 | -2.6 | 2.9 | -1.1 | 3.9 | -3.3 | -1.0 | -3.5 | 4.6 | -3.5 | -3.1 | 3.9 | 0.3 | -3.8 | 3.9 | -3.8 | -3.1 | -4.0 | 3.9 | 3.6 | 3.1 | -3.9 | -1.6 | -3.5 | 3.9 | -4.0 | 3.8 | 3.1 | -3.2 | 4.0 | 3.6 | -3.9 | -3.1 | -3.8 |
Condit. Reinf. active responses | 5.7 | 7.9 | 11.1 | -3.2 | 3.2 | -3.2 | 3.2 | 2.8 | -3.2 | -0.4 | 3.2 | -1.9 | -2.7 | -2.9 | 3.1 | -3.0 | 3.1 | 2.2 | -3.0 | 3.1 | 1.6 | -3.1 | 3.0 | -2.2 | -2.3 | 2.7 | -2.4 | 2.6 | -1.4 | 3.2 | -2.9 | -0.8 | -2.5 | 3.2 | -2.5 | -2.8 | 3.3 | 1.2 | -3.0 | 3.3 | -3.1 | -2.3 | -3.3 | 3.1 | 3.0 | 2.8 | -3.2 | -1.6 | -3.0 | 3.3 | -3.2 | 3.0 | 2.8 | -1.9 | 3.1 | 3.0 | -3.3 | -2.8 | -3.1 |
Seeking ratio, delayed vs. immediate footshock | 5.7 | 6.5 | 14.8 | -2.7 | 2.8 | -2.8 | 2.8 | 2.6 | -2.8 | -2.7 | 2.8 | 0.8 | -0.5 | -2.7 | 2.7 | -2.6 | 2.6 | 2.8 | -1.4 | 2.6 | 3.8 | -1.0 | 2.5 | 0.5 | -3.8 | 3.6 | -3.8 | 3.6 | -3.4 | 2.7 | -3.3 | -3.0 | -0.2 | 1.0 | -0.3 | -2.6 | 2.6 | 2.3 | -2.4 | 2.6 | -2.4 | 0.7 | -2.4 | 2.6 | 3.3 | 2.8 | -2.7 | -3.6 | -2.5 | 2.6 | -2.4 | 2.7 | 2.6 | 0.5 | 1.6 | 0.5 | -2.6 | -2.6 | -1.4 |
Bone: trabecular thickness | 5.6 | 6.8 | 14.6 | -3.0 | 2.8 | -2.8 | 2.8 | 2.3 | -2.8 | 0.6 | 2.8 | -3.0 | -2.6 | -2.5 | 2.8 | -2.6 | 2.9 | 1.6 | -3.1 | 2.9 | 0.9 | -3.1 | 2.9 | -2.5 | -1.7 | 2.2 | -1.8 | 2.1 | -0.8 | 3.0 | -2.5 | -0.7 | -2.8 | 3.8 | -2.8 | -2.2 | 3.0 | -0.1 | -2.9 | 3.0 | -2.9 | -2.5 | -3.1 | 2.9 | 2.6 | 2.3 | -2.9 | -1.0 | -2.9 | 2.9 | -3.1 | 2.9 | 2.3 | -2.8 | 3.1 | 2.8 | -2.9 | -2.2 | -3.1 |
Condit. Reinf. lever reinforcers received | 5.5 | 7.7 | 11.0 | -3.2 | 3.3 | -3.3 | 3.3 | 2.8 | -3.3 | -0.6 | 3.3 | -1.7 | -2.6 | -2.9 | 3.0 | -3.0 | 3.1 | 2.2 | -2.9 | 3.1 | 1.7 | -3.0 | 2.9 | -2.1 | -2.3 | 2.7 | -2.5 | 2.6 | -1.4 | 3.1 | -2.9 | -0.9 | -2.4 | 3.1 | -2.5 | -2.8 | 3.3 | 1.3 | -2.9 | 3.3 | -3.0 | -2.2 | -3.3 | 3.1 | 3.0 | 2.8 | -3.2 | -1.7 | -2.9 | 3.3 | -3.2 | 2.9 | 2.8 | -1.7 | 3.0 | 2.9 | -3.3 | -2.8 | -3.0 |
Reaction time mean minus median | 5.2 | 6.7 | 11.1 | 2.8 | -2.8 | 2.8 | -2.8 | -2.6 | 2.8 | 1.7 | -2.8 | 0.7 | 1.9 | 2.9 | -2.9 | 2.9 | -2.8 | -2.6 | 1.9 | -2.8 | -2.6 | 2.1 | -3.1 | 0.7 | 2.9 | -3.0 | 3.1 | -3.1 | 3.2 | -2.8 | 3.1 | 1.8 | 1.2 | -1.9 | 1.3 | 2.7 | -2.7 | -2.0 | 3.2 | -2.7 | 3.1 | 0.6 | 2.9 | -2.8 | -3.0 | -2.8 | 2.8 | 2.6 | 3.3 | -2.7 | 2.8 | -3.0 | -2.6 | 0.8 | -2.5 | -1.6 | 2.7 | 2.7 | 2.7 |
Condit. Reinf. active minus inactive responses | 5.1 | 6.4 | 9.3 | -2.7 | 2.8 | -2.8 | 2.8 | 2.9 | -2.8 | -1.0 | 2.8 | -1.3 | -2.8 | -2.8 | 2.7 | -3.0 | 2.7 | 2.5 | -2.1 | 2.7 | 1.7 | -2.7 | 2.7 | -1.5 | -1.9 | 2.3 | -2.2 | 2.2 | -2.0 | 2.7 | -2.5 | -0.5 | -1.6 | 2.7 | -1.7 | -2.9 | 2.9 | 2.0 | -2.7 | 2.9 | -2.8 | -1.6 | -3.0 | 2.7 | 2.5 | 2.9 | -2.7 | -1.7 | -2.9 | 2.8 | -2.7 | 2.8 | 2.9 | -1.4 | 2.9 | 2.8 | -2.8 | -2.9 | -3.0 |
Bouts of movement, locomotor time 2 | 4.9 | 5.3 | 11.7 | 2.3 | -2.3 | 2.3 | -2.3 | -3.3 | 2.3 | 1.5 | -2.3 | 0.6 | 3.1 | 3.2 | -2.3 | 3.3 | -2.3 | -3.4 | 0.7 | -2.3 | -2.2 | 2.3 | -2.3 | 0.8 | 1.3 | -1.5 | 1.8 | -1.4 | 2.1 | -2.4 | 1.8 | 0.1 | 0.2 | -2.4 | 0.2 | 3.4 | -2.3 | -3.3 | 2.4 | -2.3 | 2.4 | 0.7 | 2.5 | -2.3 | -1.9 | -3.3 | 2.3 | 2.1 | 2.3 | -2.3 | 2.0 | -2.2 | -3.3 | 0.9 | -2.6 | -2.6 | 2.3 | 3.4 | 2.6 |
Total resting periods, locomotor time 2 | 4.7 | 5.0 | 12.2 | 2.2 | -2.1 | 2.1 | -2.1 | -3.4 | 2.1 | 1.5 | -2.1 | 0.5 | 3.2 | 3.2 | -2.2 | 3.3 | -2.1 | -3.5 | 0.5 | -2.1 | -2.1 | 2.3 | -2.2 | 0.8 | 1.0 | -1.2 | 1.5 | -1.2 | 2.0 | -2.3 | 1.5 | -0.2 | -0.0 | -2.4 | -0.0 | 3.5 | -2.1 | -3.4 | 2.3 | -2.1 | 2.2 | 0.7 | 2.4 | -2.1 | -1.7 | -3.3 | 2.2 | 2.0 | 2.2 | -2.1 | 1.9 | -2.0 | -3.4 | 0.9 | -2.6 | -2.7 | 2.1 | 3.5 | 2.6 |
Extensor digitorum longus weight | 4.5 | 18.1 | 39.5 | 4.7 | -4.6 | 4.6 | -4.6 | -3.9 | 4.6 | 4.1 | -4.6 | -0.4 | 0.4 | 4.3 | -4.6 | 3.9 | -4.7 | -4.1 | 3.1 | -4.7 | -5.6 | 1.7 | -4.7 | -0.7 | 6.3 | -6.1 | 6.2 | -6.2 | 5.4 | -4.7 | 5.9 | 5.2 | 1.1 | -1.7 | 1.3 | 3.8 | -4.7 | -2.4 | 4.7 | -4.7 | 4.8 | -0.6 | 4.0 | -4.7 | -5.7 | -4.3 | 4.7 | 5.6 | 4.5 | -4.6 | 4.4 | -4.7 | -3.9 | -0.5 | -2.8 | -0.7 | 4.6 | 3.8 | 2.4 |
Reaction time mean minus median AUC | 4.4 | 5.6 | 9.2 | 2.7 | -2.7 | 2.7 | -2.7 | -2.2 | 2.7 | 1.6 | -2.7 | 0.5 | 1.2 | 2.5 | -2.5 | 2.4 | -2.7 | -2.1 | 2.0 | -2.7 | -2.5 | 1.6 | -2.7 | 0.6 | 3.0 | -3.0 | 3.0 | -3.0 | 2.6 | -2.7 | 3.0 | 2.0 | 1.3 | -1.5 | 1.3 | 2.2 | -2.6 | -1.3 | 2.8 | -2.6 | 2.7 | 0.5 | 2.6 | -2.7 | -3.0 | -2.4 | 2.6 | 2.5 | 2.7 | -2.6 | 2.6 | -2.7 | -2.2 | 0.6 | -2.1 | -1.2 | 2.6 | 2.2 | 2.0 |
Std. dev. reaction times | 4.1 | 5.6 | 9.5 | 2.5 | -2.5 | 2.5 | -2.5 | -2.7 | 2.5 | 1.7 | -2.5 | 0.2 | 1.9 | 2.8 | -2.6 | 2.9 | -2.5 | -2.8 | 1.3 | -2.5 | -2.6 | 1.8 | -2.7 | 0.3 | 2.5 | -2.6 | 2.7 | -2.6 | 3.1 | -2.5 | 2.7 | 1.5 | 0.6 | -1.8 | 0.6 | 2.8 | -2.4 | -2.6 | 2.8 | -2.4 | 2.7 | 0.3 | 2.6 | -2.5 | -2.7 | -2.9 | 2.5 | 2.6 | 2.9 | -2.4 | 2.4 | -2.6 | -2.7 | 0.3 | -2.3 | -1.6 | 2.4 | 2.8 | 2.4 |
Condit. Reinf. active-inactive response ratio | 3.9 | 4.1 | 8.3 | -1.8 | 2.1 | -2.1 | 2.1 | 2.8 | -2.1 | -1.6 | 2.1 | -0.3 | -2.6 | -2.5 | 2.1 | -2.8 | 1.9 | 2.7 | -0.8 | 1.9 | 1.7 | -1.9 | 2.1 | -0.5 | -1.4 | 1.6 | -1.8 | 1.7 | -2.5 | 1.8 | -1.9 | -0.3 | -0.3 | 1.7 | -0.3 | -2.9 | 2.1 | 2.9 | -2.2 | 2.1 | -2.2 | -0.5 | -2.3 | 1.9 | 1.8 | 2.8 | -1.8 | -1.8 | -2.5 | 2.0 | -1.8 | 2.2 | 2.8 | -0.4 | 2.2 | 2.1 | -2.0 | -2.9 | -2.5 |
Locomotion velocity, session 7 | 3.8 | 4.1 | 8.6 | -2.2 | 2.5 | -2.5 | 2.5 | 1.6 | -2.5 | 0.6 | 2.5 | -2.3 | -1.6 | -1.5 | 1.8 | -1.7 | 2.5 | 0.6 | -2.9 | 2.5 | 0.2 | -2.5 | 1.9 | -2.4 | -1.3 | 1.8 | -1.4 | 1.7 | 0.4 | 2.2 | -1.8 | -0.5 | -2.7 | 2.8 | -2.8 | -1.5 | 2.4 | -0.7 | -1.7 | 2.4 | -1.8 | -2.4 | -2.3 | 2.5 | 2.2 | 1.4 | -2.2 | -0.6 | -1.6 | 2.5 | -2.4 | 1.8 | 1.6 | -2.3 | 2.1 | 2.3 | -2.5 | -1.5 | -1.9 |
Intermitt. access day 15 inactive lever presses | 3.5 | 3.9 | 10.9 | 1.9 | -2.1 | 2.1 | -2.1 | -1.9 | 2.1 | -1.2 | -2.1 | 2.8 | 2.9 | 1.9 | -1.9 | 2.0 | -1.9 | -1.0 | 2.2 | -1.9 | 0.4 | 2.9 | -1.8 | 2.8 | 0.1 | -0.6 | 0.3 | -0.5 | -0.3 | -1.8 | 0.9 | -1.1 | 2.4 | -3.3 | 2.4 | 2.0 | -1.9 | -0.1 | 1.8 | -1.9 | 1.8 | 2.8 | 2.3 | -1.9 | -1.2 | -1.7 | 1.9 | -0.4 | 1.9 | -1.9 | 2.1 | -1.7 | -1.9 | 2.8 | -2.5 | -2.9 | 1.9 | 2.0 | 2.8 |
Post-drug Anxiety | 3.4 | 3.7 | 6.1 | 2.1 | -2.1 | 2.1 | -2.1 | -2.2 | 2.1 | 0.7 | -2.1 | 1.0 | 2.0 | 2.3 | -2.1 | 2.4 | -2.1 | -2.2 | 1.3 | -2.1 | -1.6 | 2.0 | -2.1 | 1.1 | 1.7 | -1.8 | 1.9 | -1.7 | 1.5 | -2.1 | 1.9 | 0.5 | 0.9 | -2.2 | 0.9 | 2.5 | -2.1 | -1.8 | 2.1 | -2.1 | 2.1 | 1.1 | 2.2 | -2.1 | -2.0 | -2.4 | 2.1 | 1.6 | 2.1 | -2.1 | 2.0 | -2.0 | -2.2 | 1.1 | -2.1 | -1.9 | 2.1 | 2.5 | 2.2 |
Latency to leave start box in cocaine runway, F | 3.4 | 3.8 | 5.6 | -2.2 | 2.1 | -2.1 | 2.1 | 2.2 | -2.1 | -1.1 | 2.1 | -0.8 | -1.8 | -2.4 | 2.1 | -2.3 | 2.1 | 2.2 | -1.4 | 2.1 | 1.9 | -1.8 | 2.3 | -0.7 | -1.9 | 2.0 | -2.0 | 2.0 | -1.9 | 2.2 | -2.1 | -0.9 | -0.9 | 1.8 | -0.9 | -2.2 | 2.0 | 1.7 | -2.3 | 2.0 | -2.3 | -0.8 | -2.2 | 2.1 | 2.1 | 2.2 | -2.2 | -1.7 | -2.2 | 2.1 | -2.1 | 2.2 | 2.2 | -0.7 | 2.1 | 1.7 | -2.1 | -2.2 | -2.1 |
Locomotion velocity, session 8 | 3.3 | 4.0 | 7.1 | 2.2 | -2.3 | 2.3 | -2.3 | -1.5 | 2.3 | 0.6 | -2.3 | 0.7 | 1.1 | 1.8 | -2.4 | 1.7 | -2.3 | -1.1 | 2.3 | -2.3 | -1.5 | 1.6 | -2.4 | 1.1 | 2.4 | -2.6 | 2.3 | -2.6 | 2.0 | -2.2 | 2.7 | 1.6 | 1.8 | -1.5 | 1.9 | 1.4 | -2.3 | -0.5 | 2.6 | -2.3 | 2.6 | 1.2 | 2.2 | -2.3 | -2.4 | -1.6 | 2.3 | 1.5 | 2.7 | -2.3 | 2.4 | -2.4 | -1.5 | 0.8 | -1.9 | -1.1 | 2.3 | 1.4 | 2.0 |
Fe content in liver | 3.3 | 3.9 | 11.0 | -2.0 | 2.1 | -2.1 | 2.1 | 0.9 | -2.1 | 1.7 | 2.1 | -3.0 | -2.1 | -1.2 | 1.9 | -1.3 | 2.0 | -0.0 | -3.1 | 2.0 | -0.4 | -2.7 | 1.8 | -3.2 | -0.6 | 1.2 | -0.6 | 1.0 | 0.5 | 2.0 | -1.5 | 0.6 | -3.3 | 2.7 | -3.3 | -0.9 | 2.0 | -1.5 | -1.8 | 2.0 | -1.8 | -3.1 | -2.2 | 2.0 | 1.5 | 0.8 | -2.0 | 0.5 | -1.9 | 2.1 | -2.3 | 1.8 | 0.9 | -3.2 | 2.3 | 2.5 | -2.1 | -0.9 | -2.4 |
One hour access (shock baseline) | 3.2 | 3.7 | 8.8 | -2.0 | 1.9 | -1.9 | 1.9 | 2.0 | -1.9 | -2.4 | 1.9 | 0.7 | -0.3 | -2.0 | 1.9 | -2.0 | 2.0 | 2.4 | -0.8 | 2.0 | 2.9 | -0.6 | 1.8 | 0.7 | -2.8 | 2.6 | -2.9 | 2.7 | -2.5 | 1.9 | -2.5 | -2.2 | 0.2 | 0.6 | 0.1 | -2.1 | 1.9 | 2.0 | -1.6 | 1.9 | -1.6 | 0.7 | -1.7 | 2.0 | 2.6 | 2.3 | -2.0 | -3.0 | -1.6 | 1.9 | -1.8 | 1.9 | 2.0 | 0.7 | 1.2 | 0.5 | -1.9 | -2.1 | -0.9 |
Bone: apparent density | 3.2 | 5.3 | 9.9 | -2.6 | 2.7 | -2.7 | 2.7 | 2.1 | -2.7 | -0.1 | 2.7 | -2.1 | -1.9 | -2.4 | 2.6 | -2.4 | 2.6 | 1.7 | -2.6 | 2.6 | 1.2 | -2.5 | 2.6 | -1.8 | -1.9 | 2.2 | -2.0 | 2.1 | -0.9 | 2.6 | -2.4 | -1.0 | -2.1 | 3.1 | -2.2 | -2.2 | 2.7 | 0.3 | -2.5 | 2.7 | -2.5 | -1.7 | -2.7 | 2.6 | 2.5 | 2.2 | -2.6 | -1.3 | -2.3 | 2.7 | -2.7 | 2.7 | 2.1 | -2.0 | 2.7 | 2.2 | -2.7 | -2.2 | -2.3 |
Progressive ratio test 1 inactive lever presses | 3.1 | 3.3 | 7.2 | 2.0 | -1.9 | 1.9 | -1.9 | -1.9 | 1.9 | -0.8 | -1.9 | 2.2 | 2.4 | 2.1 | -2.0 | 2.0 | -1.9 | -1.3 | 2.0 | -1.9 | -0.3 | 2.5 | -1.8 | 2.2 | 0.6 | -1.0 | 0.7 | -0.8 | 0.2 | -2.0 | 1.3 | -0.4 | 2.0 | -2.7 | 2.0 | 1.7 | -1.9 | -0.3 | 1.8 | -1.9 | 1.8 | 2.2 | 2.2 | -1.9 | -1.4 | -1.6 | 2.0 | 0.3 | 1.8 | -1.9 | 2.1 | -2.2 | -1.9 | 2.2 | -2.6 | -2.4 | 1.9 | 1.7 | 2.4 |
Bone: connectivity density | 3.1 | 4.9 | 9.5 | -2.5 | 2.7 | -2.7 | 2.7 | 1.7 | -2.7 | 0.0 | 2.7 | -1.9 | -1.4 | -2.0 | 2.4 | -2.0 | 2.6 | 1.2 | -2.8 | 2.6 | 1.1 | -2.2 | 2.5 | -1.8 | -2.1 | 2.4 | -2.1 | 2.3 | -0.6 | 2.6 | -2.5 | -1.4 | -2.3 | 3.1 | -2.4 | -1.8 | 2.6 | -0.2 | -2.3 | 2.6 | -2.3 | -1.7 | -2.5 | 2.6 | 2.6 | 1.8 | -2.6 | -1.2 | -2.1 | 2.6 | -2.7 | 2.5 | 1.7 | -1.9 | 2.4 | 1.9 | -2.6 | -1.8 | -1.9 |
Change in fecal boli incidents, locomotor task | 3.1 | 2.9 | 7.1 | -1.5 | 1.8 | -1.8 | 1.8 | 2.3 | -1.8 | -2.0 | 1.8 | 0.4 | -1.2 | -2.0 | 1.7 | -2.2 | 1.7 | 2.5 | -0.4 | 1.7 | 1.9 | -1.0 | 1.6 | 0.5 | -1.8 | 1.8 | -2.0 | 1.9 | -2.3 | 1.5 | -1.8 | -1.3 | 0.3 | 1.1 | 0.2 | -2.3 | 1.8 | 2.7 | -1.6 | 1.8 | -1.6 | 0.5 | -1.7 | 1.7 | 1.9 | 2.4 | -1.5 | -2.1 | -1.7 | 1.8 | -1.4 | 1.6 | 2.3 | 0.6 | 1.3 | 1.1 | -1.8 | -2.3 | -1.4 |
Bone: periosteal estimation | 2.9 | 5.9 | 11.3 | -2.6 | 2.7 | -2.7 | 2.7 | 2.0 | -2.7 | 0.9 | 2.7 | -3.0 | -2.8 | -2.3 | 2.5 | -2.4 | 2.6 | 1.2 | -3.0 | 2.6 | 0.4 | -3.2 | 2.5 | -2.8 | -1.2 | 1.7 | -1.3 | 1.6 | -0.1 | 2.6 | -2.0 | 0.3 | -3.0 | 3.4 | -3.0 | -2.1 | 2.6 | -0.2 | -2.6 | 2.6 | -2.6 | -2.9 | -2.9 | 2.6 | 2.2 | 2.0 | -2.5 | -0.4 | -2.4 | 2.7 | -2.8 | 2.5 | 2.0 | -2.9 | 3.0 | 3.1 | -2.7 | -2.1 | -3.0 |
Intermitt. access day 1 inactive lever presses | 2.8 | 3.0 | 4.2 | 2.0 | -2.0 | 2.0 | -2.0 | -1.9 | 2.0 | 0.1 | -2.0 | 1.3 | 1.5 | 2.0 | -1.8 | 2.0 | -2.0 | -1.7 | 1.7 | -2.0 | -1.3 | 1.9 | -1.3 | 1.2 | 1.4 | -1.6 | 1.6 | -1.6 | 0.8 | -2.0 | 1.7 | 0.6 | 1.3 | -2.1 | 1.3 | 2.0 | -2.0 | -0.8 | 1.5 | -2.0 | 1.5 | 1.2 | 2.1 | -2.0 | -1.9 | -1.9 | 2.0 | 1.3 | 1.5 | -2.0 | 2.0 | -1.8 | -1.9 | 1.2 | -1.9 | -1.8 | 2.0 | 2.0 | 1.7 |
Short access day 10 total inactive lever presses | 2.7 | 3.0 | 4.3 | 1.9 | -2.1 | 2.1 | -2.1 | -1.9 | 2.1 | 0.4 | -2.1 | 1.2 | 1.6 | 2.0 | -1.9 | 2.0 | -1.9 | -1.6 | 1.6 | -1.9 | -1.1 | 1.9 | -1.8 | 1.2 | 1.5 | -1.7 | 1.6 | -1.6 | 0.9 | -1.9 | 1.7 | 0.5 | 1.3 | -2.0 | 1.3 | 2.0 | -1.9 | -0.9 | 1.7 | -1.9 | 1.7 | 1.2 | 2.0 | -1.9 | -1.9 | -1.9 | 1.9 | 1.2 | 1.8 | -1.9 | 1.9 | -2.0 | -1.9 | 1.2 | -2.0 | -1.7 | 1.9 | 2.0 | 1.9 |
Co content in liver | 2.6 | 3.1 | 4.4 | 2.0 | -1.9 | 1.9 | -1.9 | -2.0 | 1.9 | 0.2 | -1.9 | 1.3 | 1.9 | 2.1 | -2.1 | 2.1 | -2.0 | -1.7 | 1.6 | -2.0 | -1.0 | 2.0 | -2.1 | 1.2 | 1.2 | -1.5 | 1.4 | -1.4 | 0.9 | -2.0 | 1.6 | 0.3 | 1.3 | -2.0 | 1.3 | 2.0 | -1.9 | -1.0 | 2.1 | -1.9 | 2.1 | 1.2 | 2.1 | -2.0 | -1.8 | -2.0 | 1.9 | 1.1 | 1.9 | -1.9 | 2.0 | -2.0 | -2.0 | 1.2 | -2.1 | -1.9 | 1.9 | 2.0 | 2.1 |
Reaction time mean | 2.4 | 3.4 | 8.5 | 1.9 | -1.7 | 1.7 | -1.7 | -2.0 | 1.7 | 2.1 | -1.7 | -1.0 | 0.6 | 2.1 | -1.8 | 2.0 | -1.8 | -2.4 | 0.5 | -1.8 | -2.8 | 0.6 | -1.8 | -0.9 | 2.4 | -2.3 | 2.6 | -2.4 | 2.9 | -1.8 | 2.2 | 2.1 | -0.4 | -0.6 | -0.3 | 2.1 | -1.7 | -2.6 | 1.9 | -1.7 | 1.8 | -0.9 | 1.6 | -1.8 | -2.2 | -2.3 | 1.8 | 2.8 | 1.9 | -1.7 | 1.6 | -1.7 | -2.0 | -1.0 | -1.0 | -0.3 | 1.7 | 2.1 | 1.1 |
Reaction time mean AUC | 2.4 | 3.2 | 7.7 | 1.8 | -1.7 | 1.7 | -1.7 | -2.0 | 1.7 | 2.2 | -1.7 | -1.0 | 0.4 | 2.0 | -1.8 | 1.9 | -1.8 | -2.3 | 0.5 | -1.8 | -2.8 | 0.5 | -1.7 | -0.9 | 2.4 | -2.3 | 2.5 | -2.4 | 2.7 | -1.8 | 2.2 | 2.1 | -0.4 | -0.5 | -0.3 | 2.0 | -1.7 | -2.4 | 1.8 | -1.7 | 1.7 | -0.9 | 1.5 | -1.8 | -2.2 | -2.2 | 1.8 | 2.8 | 1.7 | -1.6 | 1.5 | -1.6 | -2.0 | -1.0 | -0.9 | -0.2 | 1.6 | 2.0 | 0.9 |
Bone: minimum diameter | 2.4 | 4.4 | 10.7 | -2.0 | 2.1 | -2.1 | 2.1 | 1.8 | -2.1 | 1.4 | 2.1 | -3.0 | -3.3 | -2.0 | 2.2 | -2.1 | 2.0 | 1.0 | -2.4 | 2.0 | -0.3 | -3.2 | 2.1 | -2.9 | -0.2 | 0.7 | -0.4 | 0.6 | 0.3 | 2.0 | -1.1 | 1.2 | -2.6 | 3.2 | -2.6 | -1.9 | 2.0 | 0.1 | -2.2 | 2.0 | -2.2 | -3.0 | -2.4 | 2.0 | 1.3 | 1.7 | -1.9 | 0.3 | -2.0 | 2.0 | -2.2 | 2.1 | 1.8 | -2.9 | 3.0 | 3.3 | -2.0 | -1.9 | -3.0 |
Intermittent access terminal intake (last 3 days) | 2.3 | 2.5 | 7.8 | -1.4 | 1.4 | -1.4 | 1.4 | 1.5 | -1.4 | -2.4 | 1.4 | 1.1 | 0.2 | -1.5 | 1.4 | -1.5 | 1.5 | 2.0 | -0.3 | 1.5 | 2.8 | -0.1 | 1.3 | 1.2 | -2.6 | 2.4 | -2.7 | 2.5 | -2.5 | 1.4 | -2.1 | -2.2 | 0.6 | -0.1 | 0.5 | -1.6 | 1.4 | 1.9 | -1.2 | 1.4 | -1.2 | 1.2 | -1.1 | 1.5 | 2.1 | 1.8 | -1.4 | -2.8 | -1.2 | 1.4 | -1.2 | 1.4 | 1.5 | 1.2 | 0.6 | -0.1 | -1.4 | -1.6 | -0.3 |
Breakpoint value in progressive ratio session | 2.3 | 2.6 | 4.8 | 1.8 | -1.6 | 1.6 | -1.6 | -1.5 | 1.6 | 0.7 | -1.6 | 0.6 | 1.2 | 1.8 | -1.8 | 1.6 | -1.8 | -1.3 | 1.5 | -1.8 | -1.6 | 1.4 | -2.1 | 0.7 | 1.8 | -1.9 | 1.9 | -1.9 | 1.8 | -1.8 | 2.0 | 1.1 | 1.1 | -0.9 | 1.1 | 1.3 | -1.5 | -1.0 | 2.2 | -1.5 | 2.2 | 0.7 | 1.8 | -1.8 | -1.9 | -1.4 | 1.8 | 1.6 | 2.1 | -1.7 | 1.8 | -2.1 | -1.5 | 0.5 | -1.8 | -1.1 | 1.7 | 1.3 | 1.8 |
Time >=10cm from walls, locomotor time 1 | 2.3 | 2.3 | 4.0 | -1.7 | 1.7 | -1.7 | 1.7 | 1.7 | -1.7 | -1.0 | 1.7 | -0.4 | -0.8 | -1.9 | 1.7 | -1.7 | 1.8 | 1.7 | -1.1 | 1.8 | 1.8 | -1.1 | 1.6 | -0.2 | -1.8 | 1.8 | -1.9 | 1.8 | -1.2 | 1.8 | -1.8 | -1.2 | -0.5 | 1.2 | -0.6 | -1.7 | 1.7 | 0.9 | -1.4 | 1.7 | -1.5 | -0.3 | -1.6 | 1.8 | 2.0 | 1.8 | -1.8 | -1.8 | -1.2 | 1.7 | -1.7 | 1.7 | 1.7 | -0.3 | 1.4 | 0.9 | -1.7 | -1.7 | -1.0 |
Time >=10cm from walls, locomotor time 2 | 2.2 | 2.3 | 3.6 | -1.8 | 1.6 | -1.6 | 1.6 | 1.5 | -1.6 | -0.9 | 1.6 | -0.3 | -1.0 | -1.9 | 1.8 | -1.7 | 1.7 | 1.6 | -1.1 | 1.7 | 1.7 | -1.2 | 1.9 | -0.3 | -1.7 | 1.8 | -1.8 | 1.8 | -1.5 | 1.8 | -1.8 | -1.1 | -0.6 | 1.2 | -0.6 | -1.5 | 1.6 | 1.1 | -1.8 | 1.6 | -1.9 | -0.2 | -1.6 | 1.7 | 1.8 | 1.7 | -1.8 | -1.6 | -1.6 | 1.6 | -1.7 | 1.9 | 1.5 | -0.3 | 1.6 | 0.9 | -1.6 | -1.5 | -1.3 |
Tibialis anterior weight | 2.1 | 7.2 | 21.3 | 2.8 | -2.8 | 2.8 | -2.8 | -1.9 | 2.8 | 3.1 | -2.8 | -1.0 | -0.9 | 2.2 | -2.6 | 1.9 | -2.9 | -2.1 | 2.0 | -2.9 | -3.9 | 0.3 | -2.6 | -1.0 | 4.6 | -4.4 | 4.4 | -4.5 | 3.8 | -2.8 | 4.0 | 4.5 | 0.6 | -0.8 | 0.7 | 1.8 | -2.9 | -1.2 | 2.7 | -2.9 | 2.7 | -0.9 | 2.2 | -2.9 | -3.8 | -2.3 | 2.8 | 3.9 | 2.7 | -2.8 | 2.7 | -2.6 | -1.9 | -1.1 | -1.0 | 0.6 | 2.8 | 1.8 | 0.8 |
Saline control response | 2.1 | 2.8 | 7.5 | -1.9 | 1.9 | -1.9 | 1.9 | 1.5 | -1.9 | 0.8 | 1.9 | -1.8 | -1.9 | -1.5 | 1.5 | -1.7 | 1.9 | 0.9 | -2.1 | 1.9 | 0.3 | -2.3 | 1.4 | -2.2 | -0.6 | 1.0 | -0.8 | 0.9 | 0.4 | 1.8 | -1.2 | 0.1 | -2.1 | 2.7 | -2.1 | -1.5 | 1.8 | 0.2 | -1.4 | 1.8 | -1.3 | -2.2 | -2.0 | 1.9 | 1.5 | 1.5 | -1.9 | -0.3 | -1.3 | 1.9 | -2.0 | 1.4 | 1.5 | -1.8 | 1.9 | 2.3 | -1.9 | -1.5 | -1.9 |
Bone: endosteal estimation | 2.1 | 4.4 | 8.0 | -2.4 | 2.5 | -2.5 | 2.5 | 1.7 | -2.5 | 0.6 | 2.5 | -2.3 | -2.0 | -2.0 | 2.2 | -1.9 | 2.4 | 1.0 | -2.8 | 2.4 | 0.7 | -2.6 | 2.1 | -2.3 | -1.4 | 1.8 | -1.4 | 1.7 | -0.2 | 2.4 | -2.0 | -0.2 | -2.6 | 2.8 | -2.6 | -1.7 | 2.4 | -0.4 | -2.3 | 2.4 | -2.3 | -2.4 | -2.5 | 2.4 | 2.2 | 1.7 | -2.3 | -0.5 | -2.0 | 2.4 | -2.5 | 2.2 | 1.7 | -2.3 | 2.4 | 2.4 | -2.4 | -1.7 | -2.3 |
Bone: trabecular spacing | 2.1 | 2.7 | 6.5 | 1.9 | -1.9 | 1.9 | -1.9 | -1.4 | 1.9 | 0.0 | -1.9 | 1.4 | 1.2 | 1.6 | -1.8 | 1.6 | -2.0 | -1.1 | 2.0 | -2.0 | -1.0 | 1.7 | -1.9 | 1.2 | 1.5 | -1.7 | 1.5 | -1.7 | 0.5 | -1.9 | 1.8 | 1.1 | 1.6 | -2.6 | 1.6 | 1.4 | -2.0 | 0.0 | 1.7 | -2.0 | 1.7 | 1.4 | 1.9 | -2.0 | -1.9 | -1.5 | 2.0 | 1.0 | 1.5 | -1.9 | 2.0 | -1.8 | -1.4 | 1.3 | -1.8 | -1.5 | 1.9 | 1.4 | 1.5 |
Locomotion distance, session 7 | 2.0 | 2.6 | 5.7 | -1.8 | 2.1 | -2.1 | 2.1 | 0.9 | -2.1 | -0.1 | 2.1 | -1.3 | -0.5 | -1.0 | 1.5 | -1.1 | 2.0 | 0.3 | -2.4 | 2.0 | 0.6 | -1.4 | 1.7 | -1.4 | -1.8 | 2.0 | -1.7 | 2.0 | -0.3 | 1.7 | -2.0 | -1.3 | -2.1 | 1.7 | -2.1 | -0.8 | 2.0 | -0.8 | -1.6 | 2.0 | -1.7 | -1.4 | -1.7 | 2.0 | 2.1 | 0.9 | -1.7 | -0.9 | -1.4 | 2.0 | -1.9 | 1.6 | 0.9 | -1.3 | 1.4 | 1.0 | -2.0 | -0.8 | -1.2 |
Time in open arm before self-admin | 2.0 | 2.2 | 5.0 | -1.5 | 1.6 | -1.6 | 1.6 | 2.0 | -1.6 | -0.5 | 1.6 | -1.2 | -1.7 | -1.9 | 1.8 | -2.1 | 1.5 | 2.0 | -0.8 | 1.5 | 1.0 | -1.7 | 1.2 | -0.9 | -0.9 | 1.0 | -1.1 | 0.9 | -0.7 | 1.6 | -1.1 | 0.1 | -0.5 | 1.9 | -0.5 | -2.2 | 1.6 | 1.7 | -1.2 | 1.6 | -1.1 | -0.9 | -1.7 | 1.5 | 1.4 | 2.1 | -1.6 | -1.0 | -1.1 | 1.5 | -1.4 | 1.5 | 2.0 | -0.9 | 1.6 | 1.8 | -1.5 | -2.2 | -1.6 |
Cu content in liver | 2.0 | 2.5 | 5.8 | -1.8 | 1.9 | -1.9 | 1.9 | 1.1 | -1.9 | -1.4 | 1.9 | 0.3 | 0.2 | -1.3 | 1.5 | -1.2 | 1.8 | 1.1 | -1.6 | 1.8 | 2.1 | -0.6 | 1.5 | -0.1 | -2.4 | 2.4 | -2.3 | 2.4 | -1.4 | 1.8 | -2.3 | -2.2 | -0.9 | 0.7 | -1.0 | -1.1 | 1.8 | 0.5 | -1.6 | 1.8 | -1.6 | -0.1 | -1.5 | 1.8 | 2.3 | 1.3 | -1.8 | -1.9 | -1.3 | 1.9 | -1.8 | 1.5 | 1.1 | 0.2 | 0.8 | 0.2 | -1.9 | -1.1 | -0.5 |
Bone: marrow area | 1.9 | 4.1 | 7.4 | -2.3 | 2.4 | -2.4 | 2.4 | 1.6 | -2.4 | 0.5 | 2.4 | -2.2 | -2.0 | -1.9 | 2.1 | -1.9 | 2.3 | 1.0 | -2.6 | 2.3 | 0.6 | -2.5 | 2.1 | -2.2 | -1.3 | 1.7 | -1.3 | 1.6 | -0.3 | 2.3 | -1.9 | -0.2 | -2.5 | 2.7 | -2.5 | -1.6 | 2.3 | -0.3 | -2.3 | 2.3 | -2.3 | -2.3 | -2.4 | 2.3 | 2.1 | 1.6 | -2.2 | -0.5 | -1.9 | 2.3 | -2.4 | 2.1 | 1.6 | -2.3 | 2.4 | 2.3 | -2.3 | -1.6 | -2.2 |
Number of licking bursts | 1.8 | 2.1 | 3.5 | -1.7 | 1.7 | -1.7 | 1.7 | 1.2 | -1.7 | -0.1 | 1.7 | -1.0 | -1.1 | -1.4 | 1.8 | -1.3 | 1.7 | 0.8 | -1.8 | 1.7 | 0.8 | -1.5 | 1.9 | -1.2 | -1.4 | 1.5 | -1.3 | 1.5 | -0.6 | 1.6 | -1.7 | -0.6 | -1.5 | 1.2 | -1.6 | -1.1 | 1.7 | 0.1 | -1.7 | 1.7 | -1.7 | -1.2 | -1.7 | 1.7 | 1.6 | 1.2 | -1.6 | -0.8 | -1.7 | 1.7 | -1.7 | 1.8 | 1.2 | -1.0 | 1.7 | 1.2 | -1.7 | -1.1 | -1.5 |
Reaction time premature initiation rate | 1.8 | 2.4 | 10.5 | -0.7 | 0.7 | -0.7 | 0.7 | 1.5 | -0.7 | -3.1 | 0.7 | 2.5 | 0.5 | -1.3 | 0.7 | -1.4 | 0.7 | 2.5 | 1.2 | 0.7 | 2.9 | 0.8 | 0.3 | 2.4 | -1.8 | 1.5 | -2.0 | 1.6 | -2.7 | 0.7 | -1.2 | -2.1 | 2.2 | -0.7 | 2.1 | -1.9 | 0.6 | 3.2 | -0.3 | 0.6 | -0.3 | 2.5 | -0.4 | 0.7 | 1.3 | 1.9 | -0.8 | -2.8 | -0.4 | 0.7 | -0.3 | 0.4 | 1.5 | 2.5 | -0.3 | -0.7 | -0.7 | -1.9 | 0.3 |
Compulsive drug intake | 1.8 | 1.8 | 4.4 | 1.4 | -1.4 | 1.4 | -1.4 | -1.5 | 1.4 | 1.6 | -1.4 | -0.4 | 0.2 | 1.4 | -1.2 | 1.5 | -1.4 | -1.8 | 0.5 | -1.4 | -2.1 | 0.5 | -1.0 | -0.5 | 1.9 | -1.8 | 2.0 | -1.8 | 1.6 | -1.4 | 1.7 | 1.4 | -0.3 | -0.5 | -0.2 | 1.7 | -1.4 | -1.6 | 0.9 | -1.4 | 0.9 | -0.5 | 1.2 | -1.4 | -1.8 | -1.8 | 1.4 | 2.1 | 0.9 | -1.4 | 1.2 | -1.1 | -1.5 | -0.5 | -0.8 | -0.4 | 1.4 | 1.7 | 0.5 |
Bone: trabecular tissue density | 1.8 | 2.5 | 3.8 | 1.7 | -1.8 | 1.8 | -1.8 | -1.8 | 1.8 | 1.2 | -1.8 | 0.1 | 1.2 | 2.0 | -1.9 | 1.9 | -1.6 | -1.8 | 0.9 | -1.6 | -1.6 | 1.2 | -1.7 | 0.2 | 1.7 | -1.8 | 1.8 | -1.8 | 1.9 | -1.7 | 1.8 | 1.0 | 0.4 | -1.2 | 0.5 | 1.9 | -1.7 | -1.6 | 1.7 | -1.7 | 1.7 | 0.1 | 1.7 | -1.6 | -1.7 | -1.9 | 1.7 | 1.6 | 1.8 | -1.7 | 1.5 | -1.9 | -1.8 | 0.2 | -1.6 | -1.1 | 1.7 | 1.9 | 1.5 |
Time to tail flick, vehicle, before self-admin | 1.8 | 1.8 | 3.1 | -1.6 | 1.6 | -1.6 | 1.6 | 1.7 | -1.6 | -0.3 | 1.6 | -0.6 | -0.9 | -1.5 | 1.5 | -1.7 | 1.7 | 1.7 | -1.1 | 1.7 | 1.4 | -1.3 | 0.9 | -0.5 | -1.2 | 1.4 | -1.5 | 1.4 | -0.7 | 1.6 | -1.3 | -0.8 | -0.6 | 1.5 | -0.7 | -1.7 | 1.7 | 0.9 | -0.9 | 1.7 | -0.9 | -0.5 | -1.5 | 1.7 | 1.7 | 1.8 | -1.6 | -1.4 | -1.0 | 1.6 | -1.5 | 0.9 | 1.7 | -0.6 | 0.9 | 1.2 | -1.6 | -1.7 | -1.1 |
Delay disc. indifference point, 16s delay | 1.8 | 1.9 | 3.0 | 1.5 | -1.4 | 1.4 | -1.4 | -1.7 | 1.4 | 0.3 | -1.4 | 0.8 | 1.6 | 1.7 | -1.5 | 1.7 | -1.5 | -1.5 | 1.1 | -1.5 | -0.9 | 1.6 | -1.6 | 0.8 | 0.9 | -1.1 | 1.1 | -1.0 | 0.9 | -1.5 | 1.2 | 0.2 | 0.8 | -1.6 | 0.9 | 1.6 | -1.5 | -1.2 | 1.5 | -1.5 | 1.5 | 1.0 | 1.6 | -1.5 | -1.3 | -1.6 | 1.5 | 1.0 | 1.5 | -1.4 | 1.5 | -1.6 | -1.7 | 0.7 | -1.7 | -1.4 | 1.4 | 1.6 | 1.6 |
Cd content in liver | 1.8 | 2.0 | 5.2 | 1.6 | -1.6 | 1.6 | -1.6 | -1.1 | 1.6 | -0.8 | -1.6 | 1.8 | 1.4 | 1.2 | -1.4 | 1.3 | -1.6 | -0.6 | 1.9 | -1.6 | -0.1 | 1.9 | -1.3 | 1.7 | 0.6 | -0.9 | 0.6 | -0.8 | -0.3 | -1.6 | 1.1 | 0.1 | 1.8 | -2.3 | 1.8 | 1.1 | -1.6 | 0.3 | 1.3 | -1.6 | 1.3 | 1.8 | 1.6 | -1.6 | -1.3 | -1.1 | 1.7 | 0.1 | 1.3 | -1.6 | 1.7 | -1.3 | -1.1 | 1.7 | -1.6 | -1.7 | 1.6 | 1.1 | 1.6 |
Delay discounting water rate 6 sec | 1.7 | 2.4 | 4.4 | -1.7 | 1.8 | -1.8 | 1.8 | 1.4 | -1.8 | -0.5 | 1.8 | -0.5 | -0.6 | -1.2 | 1.5 | -1.4 | 1.9 | 1.1 | -1.8 | 1.9 | 1.4 | -1.2 | 1.5 | -0.8 | -1.9 | 2.1 | -2.0 | 2.1 | -1.5 | 1.7 | -2.1 | -1.4 | -1.3 | 1.3 | -1.4 | -1.2 | 2.0 | 0.4 | -1.7 | 2.0 | -1.7 | -0.8 | -1.8 | 1.9 | 2.1 | 1.4 | -1.7 | -1.6 | -1.8 | 1.9 | -1.9 | 1.5 | 1.4 | -0.6 | 1.2 | 0.9 | -1.9 | -1.2 | -1.3 |
Light reinforcement 2 | 1.7 | 2.3 | 3.7 | 1.7 | -1.7 | 1.7 | -1.7 | -1.7 | 1.7 | 0.6 | -1.7 | 0.5 | 1.1 | 1.7 | -1.6 | 1.8 | -1.8 | -1.6 | 1.2 | -1.8 | -1.5 | 1.4 | -1.5 | 0.5 | 1.5 | -1.7 | 1.7 | -1.7 | 1.5 | -1.8 | 1.7 | 1.0 | 0.8 | -1.5 | 0.8 | 1.6 | -1.7 | -1.2 | 1.4 | -1.7 | 1.4 | 0.4 | 1.7 | -1.8 | -1.8 | -1.7 | 1.7 | 1.5 | 1.9 | -1.6 | 1.7 | -1.5 | -1.7 | 0.4 | -1.3 | -1.1 | 1.6 | 1.6 | 1.6 |
Total zone transitions, hab. session 2 | 1.7 | 2.2 | 5.3 | 1.7 | -1.5 | 1.5 | -1.5 | -0.8 | 1.5 | 0.5 | -1.5 | 0.3 | 0.7 | 1.4 | -2.2 | 1.2 | -1.5 | -0.8 | 1.4 | -1.5 | -1.3 | 1.0 | -2.1 | 0.5 | 2.1 | -2.1 | 1.9 | -2.0 | 2.0 | -1.7 | 2.1 | 1.5 | 1.1 | -1.0 | 1.1 | 0.9 | -1.5 | -0.5 | 2.2 | -1.5 | 2.3 | 0.4 | 1.5 | -1.5 | -1.7 | -0.9 | 1.8 | 1.2 | 2.3 | -1.5 | 1.7 | -2.0 | -0.8 | 0.3 | -1.5 | -0.5 | 1.5 | 0.9 | 1.6 |
Context. condit. distance diff. score | 1.6 | 1.9 | 7.1 | 1.1 | -1.1 | 1.1 | -1.1 | 0.1 | 1.1 | -1.4 | -1.1 | 2.1 | 1.3 | 0.5 | -1.6 | 0.4 | -1.1 | 0.8 | 2.3 | -1.1 | 0.9 | 1.7 | -1.7 | 2.4 | 0.6 | -0.9 | 0.4 | -0.8 | 0.0 | -1.0 | 1.1 | -0.3 | 2.6 | -1.3 | 2.7 | -0.2 | -1.1 | 1.3 | 2.0 | -1.1 | 1.9 | 2.4 | 1.4 | -1.1 | -0.8 | 0.2 | 1.1 | -0.8 | 1.9 | -1.1 | 1.4 | -1.6 | 0.1 | 2.2 | -1.8 | -1.3 | 1.1 | -0.2 | 1.9 |
Locomotion velocity, session 1 | 1.6 | 1.7 | 4.4 | 1.5 | -1.5 | 1.5 | -1.5 | -0.5 | 1.5 | 0.1 | -1.5 | 0.9 | -0.0 | 0.8 | -1.4 | 0.7 | -1.6 | -0.1 | 2.1 | -1.6 | -0.9 | 1.0 | -1.5 | 1.0 | 1.6 | -1.8 | 1.5 | -1.7 | 0.5 | -1.6 | 1.8 | 1.4 | 1.8 | -0.9 | 1.8 | 0.4 | -1.6 | 0.9 | 1.4 | -1.6 | 1.4 | 1.1 | 1.4 | -1.6 | -1.8 | -0.6 | 1.5 | 0.8 | 1.3 | -1.6 | 1.7 | -1.3 | -0.5 | 0.9 | -1.0 | -0.4 | 1.6 | 0.4 | 0.8 |
Bone: trabecular number | 1.6 | 2.4 | 6.5 | -1.8 | 1.9 | -1.9 | 1.9 | 1.0 | -1.9 | 0.4 | 1.9 | -1.7 | -0.9 | -1.3 | 1.7 | -1.2 | 1.8 | 0.6 | -2.2 | 1.8 | 0.5 | -1.6 | 1.7 | -1.6 | -1.4 | 1.6 | -1.3 | 1.5 | -0.1 | 1.8 | -1.7 | -1.0 | -1.9 | 2.5 | -2.0 | -1.0 | 1.9 | -0.7 | -1.5 | 1.9 | -1.5 | -1.5 | -1.7 | 1.8 | 1.7 | 1.0 | -1.8 | -0.6 | -1.3 | 1.9 | -1.9 | 1.8 | 1.0 | -1.7 | 1.7 | 1.3 | -1.9 | -1.0 | -1.3 |
Time to tail flick, vehicle, after self-admin | 1.6 | 1.7 | 4.6 | -1.6 | 1.4 | -1.4 | 1.4 | 1.4 | -1.4 | -0.9 | 1.4 | 0.3 | -0.1 | -1.4 | 1.2 | -1.3 | 1.5 | 1.6 | -0.9 | 1.5 | 2.2 | -0.5 | 0.9 | 0.2 | -1.6 | 1.8 | -1.8 | 1.8 | -1.3 | 1.6 | -1.6 | -1.6 | -0.2 | 0.9 | -0.3 | -1.4 | 1.5 | 0.9 | -0.9 | 1.5 | -1.0 | 0.2 | -1.3 | 1.5 | 1.8 | 1.5 | -1.6 | -2.0 | -0.8 | 1.4 | -1.4 | 0.9 | 1.4 | 0.2 | 0.6 | 0.4 | -1.4 | -1.4 | -0.4 |
Area under the delay curve | 1.6 | 1.7 | 2.8 | 1.3 | -1.4 | 1.4 | -1.4 | -1.6 | 1.4 | 0.5 | -1.4 | 0.8 | 1.6 | 1.6 | -1.4 | 1.7 | -1.3 | -1.5 | 0.9 | -1.3 | -0.8 | 1.4 | -1.7 | 0.7 | 0.9 | -1.0 | 1.0 | -1.0 | 1.1 | -1.3 | 1.1 | 0.1 | 0.6 | -1.5 | 0.7 | 1.6 | -1.3 | -1.2 | 1.6 | -1.3 | 1.6 | 0.9 | 1.5 | -1.3 | -1.2 | -1.5 | 1.3 | 0.8 | 1.5 | -1.4 | 1.3 | -1.5 | -1.6 | 0.8 | -1.6 | -1.4 | 1.4 | 1.6 | 1.6 |
Reaction time omissions | 1.5 | 2.0 | 4.5 | 1.3 | -1.4 | 1.4 | -1.4 | -1.6 | 1.4 | 1.5 | -1.4 | -0.2 | 0.7 | 1.5 | -1.6 | 1.6 | -1.5 | -1.7 | 0.7 | -1.5 | -1.8 | 0.7 | -1.5 | -0.2 | 1.8 | -1.8 | 2.0 | -1.8 | 2.1 | -1.3 | 1.8 | 1.3 | 0.1 | -0.6 | 0.2 | 1.6 | -1.5 | -1.2 | 1.7 | -1.5 | 1.6 | -0.3 | 1.4 | -1.5 | -1.8 | -1.8 | 1.4 | 2.0 | 1.6 | -1.4 | 1.3 | -1.5 | -1.6 | -0.0 | -1.1 | -0.5 | 1.4 | 1.6 | 1.1 |
Condit. Reinf. active responses | 1.5 | 1.8 | 7.7 | 0.2 | -0.2 | 0.2 | -0.2 | -0.4 | 0.2 | 2.8 | -0.2 | -2.7 | -1.7 | 0.2 | 0.0 | 0.1 | -0.2 | -1.0 | -1.0 | -0.2 | -2.2 | -1.6 | -0.1 | -2.6 | 1.9 | -1.5 | 1.9 | -1.6 | 2.4 | -0.1 | 1.2 | 2.5 | -1.9 | 1.7 | -1.8 | 0.5 | -0.1 | -1.7 | 0.2 | -0.1 | 0.2 | -2.6 | -0.3 | -0.2 | -1.0 | -0.7 | 0.2 | 2.4 | 0.1 | -0.2 | -0.2 | 0.1 | -0.4 | -2.7 | 1.1 | 1.8 | 0.2 | 0.5 | -1.2 |
Incentive salience index mean | 1.5 | 1.8 | 8.0 | 0.5 | -0.5 | 0.5 | -0.5 | -0.3 | 0.5 | 2.6 | -0.5 | -2.3 | -1.6 | 0.3 | -0.5 | 0.2 | -0.5 | -0.8 | -0.5 | -0.5 | -2.2 | -1.4 | -0.7 | -2.3 | 2.4 | -2.0 | 2.2 | -2.1 | 2.8 | -0.3 | 1.7 | 2.6 | -1.3 | 1.7 | -1.2 | 0.4 | -0.4 | -1.4 | 0.8 | -0.4 | 0.9 | -2.2 | 0.0 | -0.5 | -1.3 | -0.6 | 0.6 | 2.4 | 0.8 | -0.5 | 0.2 | -0.5 | -0.3 | -2.3 | 0.7 | 1.7 | 0.5 | 0.4 | -0.7 |
Bone: cortical tissue density | 1.5 | 1.9 | 2.9 | 1.6 | -1.6 | 1.6 | -1.6 | -1.1 | 1.6 | 0.3 | -1.6 | 0.8 | 0.9 | 1.4 | -1.7 | 1.3 | -1.6 | -0.8 | 1.6 | -1.6 | -1.0 | 1.3 | -1.6 | 0.9 | 1.5 | -1.6 | 1.5 | -1.6 | 1.1 | -1.6 | 1.7 | 0.8 | 1.3 | -1.3 | 1.3 | 1.1 | -1.5 | -0.2 | 1.7 | -1.5 | 1.7 | 1.0 | 1.6 | -1.6 | -1.6 | -1.1 | 1.6 | 0.9 | 1.6 | -1.6 | 1.6 | -1.6 | -1.1 | 0.9 | -1.4 | -1.0 | 1.6 | 1.1 | 1.4 |
Distance traveled after self-admin | 1.5 | 1.7 | 4.6 | 1.2 | -1.3 | 1.3 | -1.3 | -1.0 | 1.3 | -0.8 | -1.3 | 1.8 | 2.1 | 1.1 | -0.9 | 1.2 | -1.1 | -0.5 | 1.6 | -1.1 | 0.4 | 2.0 | -1.4 | 2.2 | 0.1 | -0.4 | 0.2 | -0.3 | -0.1 | -1.1 | 0.7 | -0.9 | 1.9 | -1.9 | 1.8 | 0.9 | -1.2 | 0.1 | 1.4 | -1.2 | 1.4 | 1.9 | 1.5 | -1.1 | -0.7 | -0.8 | 1.2 | -0.5 | 1.4 | -1.3 | 1.3 | -1.1 | -1.0 | 2.1 | -1.8 | -2.0 | 1.3 | 0.9 | 1.9 |
Reaction time premature initiations | 1.4 | 2.0 | 9.7 | -1.0 | 1.1 | -1.1 | 1.1 | 1.8 | -1.1 | -2.3 | 1.1 | 1.5 | -0.4 | -1.7 | 1.1 | -1.8 | 1.0 | 2.5 | 0.6 | 1.0 | 2.4 | -0.1 | 0.6 | 1.5 | -1.5 | 1.4 | -1.8 | 1.4 | -2.2 | 1.0 | -1.2 | -1.4 | 1.4 | 0.3 | 1.4 | -2.2 | 1.0 | 3.1 | -0.6 | 1.0 | -0.6 | 1.5 | -0.9 | 1.0 | 1.4 | 2.1 | -1.1 | -2.3 | -0.7 | 1.0 | -0.7 | 0.7 | 1.8 | 1.6 | 0.3 | 0.3 | -1.0 | -2.2 | -0.4 |
Cocaine response after cond. not corrected | 1.4 | 1.5 | 5.1 | -0.8 | 0.9 | -0.9 | 0.9 | 1.5 | -0.9 | -2.3 | 0.9 | 0.9 | -0.4 | -1.4 | 1.1 | -1.4 | 1.0 | 1.9 | 0.2 | 1.0 | 1.8 | -0.1 | 1.3 | 1.1 | -1.5 | 1.3 | -1.6 | 1.4 | -2.2 | 0.9 | -1.3 | -1.3 | 0.9 | 0.1 | 0.8 | -1.5 | 1.0 | 2.0 | -1.4 | 1.0 | -1.3 | 1.2 | -0.9 | 1.0 | 1.3 | 1.6 | -0.8 | -2.0 | -1.2 | 0.9 | -0.8 | 1.3 | 1.5 | 0.9 | 0.7 | 0.1 | -0.9 | -1.5 | -0.6 |
Condit. Reinf. lever presses | 1.4 | 1.9 | 3.7 | -1.5 | 1.6 | -1.6 | 1.6 | 1.9 | -1.6 | -0.9 | 1.6 | -0.5 | -1.6 | -1.6 | 1.1 | -1.8 | 1.5 | 1.7 | -1.0 | 1.5 | 1.1 | -1.5 | 1.0 | -0.6 | -0.9 | 1.1 | -1.2 | 1.1 | -0.7 | 1.5 | -1.2 | -0.1 | -0.6 | 1.5 | -0.6 | -1.9 | 1.6 | 1.4 | -1.0 | 1.6 | -1.2 | -0.7 | -1.6 | 1.5 | 1.4 | 1.9 | -1.5 | -1.1 | -1.1 | 1.7 | -1.4 | 1.0 | 1.9 | -0.5 | 1.3 | 1.7 | -1.7 | -1.9 | -1.4 |
Conditioned reinforcement - inactives | 1.4 | 1.6 | 2.8 | 1.5 | -1.5 | 1.5 | -1.5 | -1.5 | 1.5 | 0.5 | -1.5 | 0.5 | 1.1 | 1.5 | -1.5 | 1.6 | -1.4 | -1.4 | 0.9 | -1.4 | -1.1 | 1.2 | -1.2 | 0.6 | 1.2 | -1.2 | 1.3 | -1.2 | 0.8 | -1.5 | 1.2 | 0.5 | 0.6 | -1.4 | 0.6 | 1.7 | -1.4 | -1.1 | 1.3 | -1.4 | 1.3 | 0.6 | 1.4 | -1.4 | -1.4 | -1.6 | 1.5 | 1.1 | 1.1 | -1.4 | 1.3 | -1.4 | -1.5 | 0.6 | -1.3 | -1.2 | 1.4 | 1.7 | 1.1 |
Degree of sensitization distance | 1.4 | 1.4 | 3.5 | -1.3 | 1.4 | -1.4 | 1.4 | 0.8 | -1.4 | -1.1 | 1.4 | -0.1 | -0.3 | -1.0 | 1.4 | -1.0 | 1.2 | 0.8 | -1.0 | 1.2 | 1.1 | -0.6 | 1.6 | -0.1 | -1.9 | 1.8 | -1.7 | 1.8 | -1.7 | 1.2 | -1.8 | -1.2 | -0.7 | 0.3 | -0.7 | -0.8 | 1.2 | 0.4 | -1.5 | 1.2 | -1.6 | -0.2 | -1.2 | 1.2 | 1.5 | 0.9 | -1.3 | -1.2 | -1.7 | 1.2 | -1.3 | 1.6 | 0.8 | -0.1 | 1.1 | 0.3 | -1.2 | -0.8 | -1.0 |
Condit. Reinf. active minus inactive responses | 1.4 | 1.6 | 6.6 | 0.5 | -0.4 | 0.4 | -0.4 | -0.3 | 0.4 | 2.4 | -0.4 | -2.2 | -1.4 | 0.3 | -0.4 | 0.2 | -0.4 | -0.9 | -0.7 | -0.4 | -2.1 | -1.4 | -0.6 | -2.3 | 2.1 | -1.7 | 2.0 | -1.8 | 2.6 | -0.3 | 1.4 | 2.3 | -1.5 | 1.7 | -1.4 | 0.4 | -0.3 | -1.4 | 0.6 | -0.3 | 0.7 | -2.2 | -0.1 | -0.4 | -1.1 | -0.6 | 0.5 | 2.2 | 0.6 | -0.4 | 0.1 | -0.3 | -0.3 | -2.2 | 0.7 | 1.6 | 0.4 | 0.4 | -0.7 |
Condit. Reinf. active-inactive response ratio | 1.4 | 1.5 | 6.7 | 0.8 | -0.6 | 0.6 | -0.6 | -0.1 | 0.6 | 2.1 | -0.6 | -1.7 | -1.7 | 0.4 | -0.8 | 0.1 | -0.5 | -0.6 | -0.1 | -0.5 | -2.2 | -1.2 | -0.9 | -1.9 | 2.5 | -2.0 | 2.2 | -2.1 | 2.3 | -0.6 | 1.7 | 2.6 | -0.9 | 1.6 | -0.8 | 0.1 | -0.5 | -0.5 | 0.9 | -0.5 | 0.9 | -1.8 | 0.1 | -0.5 | -1.4 | -0.4 | 0.7 | 2.2 | 0.7 | -0.5 | 0.4 | -0.7 | -0.1 | -1.8 | 0.5 | 1.7 | 0.5 | 0.1 | -0.7 |
Bone: cortical area | 1.4 | 2.2 | 4.5 | -1.5 | 1.6 | -1.6 | 1.6 | 1.4 | -1.6 | 0.6 | 1.6 | -1.9 | -1.9 | -1.4 | 1.5 | -1.5 | 1.6 | 0.9 | -1.7 | 1.6 | 0.1 | -2.0 | 1.6 | -1.6 | -0.6 | 0.9 | -0.7 | 0.9 | -0.0 | 1.5 | -1.1 | 0.2 | -1.7 | 2.1 | -1.7 | -1.4 | 1.6 | 0.1 | -1.6 | 1.6 | -1.6 | -1.7 | -1.8 | 1.6 | 1.3 | 1.3 | -1.5 | -0.2 | -1.5 | 1.6 | -1.7 | 1.5 | 1.4 | -1.7 | 1.9 | 2.0 | -1.6 | -1.4 | -1.9 |
Rest time, locomotor task time 2 | 1.4 | 1.6 | 13.0 | 0.4 | -0.4 | 0.4 | -0.4 | -1.9 | 0.4 | 2.1 | -0.4 | -1.4 | 1.4 | 1.5 | -0.1 | 1.9 | -0.3 | -2.8 | -1.6 | -0.3 | -1.8 | 0.2 | 0.2 | -1.0 | 0.0 | 0.1 | 0.6 | 0.1 | 1.3 | -0.3 | -0.1 | -0.4 | -2.1 | -0.6 | -2.1 | 2.6 | -0.5 | -3.6 | -0.2 | -0.5 | -0.2 | -1.6 | 0.5 | -0.3 | -0.2 | -2.3 | 0.4 | 1.7 | 0.0 | -0.5 | -0.1 | -0.0 | -1.9 | -0.9 | -0.3 | -1.2 | 0.5 | 2.6 | 0.5 |
Median of all reaction times | 1.3 | 1.8 | 5.9 | 1.1 | -1.0 | 1.0 | -1.0 | -1.4 | 1.0 | 2.0 | -1.0 | -1.6 | -0.2 | 1.3 | -1.1 | 1.3 | -1.1 | -1.9 | -0.2 | -1.1 | -2.4 | -0.2 | -1.0 | -1.4 | 1.9 | -1.7 | 2.0 | -1.8 | 2.4 | -1.1 | 1.5 | 2.0 | -1.0 | 0.1 | -0.9 | 1.4 | -1.0 | -2.2 | 1.0 | -1.0 | 1.0 | -1.4 | 0.8 | -1.1 | -1.5 | -1.6 | 1.1 | 2.4 | 1.0 | -1.0 | 0.8 | -0.9 | -1.4 | -1.6 | -0.2 | 0.4 | 1.0 | 1.4 | 0.2 |
Intermittent access intake escalation 2 | 1.3 | 1.3 | 3.3 | -1.2 | 1.0 | -1.0 | 1.0 | 1.3 | -1.0 | -1.1 | 1.0 | 0.3 | -0.4 | -1.4 | 1.4 | -1.3 | 1.2 | 1.5 | -0.4 | 1.2 | 1.8 | -0.5 | 1.2 | 0.3 | -1.6 | 1.5 | -1.7 | 1.6 | -1.5 | 1.2 | -1.4 | -1.2 | 0.1 | 0.4 | 0.1 | -1.1 | 1.2 | 1.3 | -1.2 | 1.2 | -1.2 | 0.3 | -1.0 | 1.2 | 1.5 | 1.4 | -1.2 | -1.8 | -1.1 | 1.0 | -1.1 | 1.5 | 1.3 | 0.3 | 1.0 | 0.3 | -1.0 | -1.1 | -0.7 |
Bone: cortical apparent density | 1.3 | 1.7 | 2.6 | 1.5 | -1.5 | 1.5 | -1.5 | -1.0 | 1.5 | 0.4 | -1.5 | 0.7 | 0.8 | 1.3 | -1.6 | 1.2 | -1.5 | -0.8 | 1.4 | -1.5 | -1.0 | 1.1 | -1.5 | 0.8 | 1.5 | -1.6 | 1.4 | -1.5 | 1.1 | -1.5 | 1.6 | 0.8 | 1.2 | -1.2 | 1.2 | 1.0 | -1.4 | -0.3 | 1.6 | -1.4 | 1.6 | 0.8 | 1.5 | -1.5 | -1.5 | -1.1 | 1.5 | 0.9 | 1.6 | -1.5 | 1.5 | -1.6 | -1.0 | 0.8 | -1.3 | -0.9 | 1.5 | 1.0 | 1.3 |
Bone: periosteal perimeter | 1.3 | 2.2 | 3.7 | -1.6 | 1.7 | -1.7 | 1.7 | 1.1 | -1.7 | 0.2 | 1.7 | -1.5 | -1.3 | -1.3 | 1.7 | -1.3 | 1.7 | 0.7 | -1.9 | 1.7 | 0.6 | -1.7 | 1.7 | -1.4 | -1.3 | 1.5 | -1.2 | 1.4 | -0.5 | 1.7 | -1.6 | -0.5 | -1.7 | 1.9 | -1.8 | -1.1 | 1.7 | -0.1 | -1.7 | 1.7 | -1.7 | -1.5 | -1.7 | 1.7 | 1.6 | 1.1 | -1.5 | -0.5 | -1.6 | 1.7 | -1.8 | 1.6 | 1.1 | -1.4 | 1.7 | 1.5 | -1.7 | -1.1 | -1.6 |
Delta ambulatory time before/after self-admin | 1.3 | 1.4 | 5.6 | -0.8 | 0.7 | -0.7 | 0.7 | 0.7 | -0.7 | -2.0 | 0.7 | 1.5 | 0.5 | -0.9 | 1.2 | -0.7 | 0.9 | 1.2 | -0.0 | 0.9 | 2.1 | 0.4 | 1.2 | 1.4 | -2.0 | 1.8 | -2.0 | 1.9 | -2.4 | 0.8 | -1.6 | -2.1 | 0.7 | -0.6 | 0.6 | -0.7 | 0.8 | 1.4 | -1.2 | 0.8 | -1.2 | 1.4 | -0.6 | 0.9 | 1.4 | 0.9 | -0.9 | -2.1 | -1.1 | 0.7 | -0.7 | 1.1 | 0.7 | 1.5 | 0.2 | -0.8 | -0.7 | -0.7 | -0.1 |
Latency to leave start box in cocaine runway | 1.3 | 1.4 | 2.8 | -1.3 | 1.2 | -1.2 | 1.2 | 1.3 | -1.2 | -0.1 | 1.2 | -0.9 | -1.5 | -1.4 | 1.3 | -1.4 | 1.2 | 1.1 | -1.0 | 1.2 | 0.7 | -1.4 | 1.6 | -1.0 | -0.8 | 1.0 | -0.9 | 0.9 | -1.0 | 1.3 | -1.1 | -0.1 | -0.9 | 1.4 | -0.9 | -1.2 | 1.1 | 0.8 | -1.7 | 1.1 | -1.7 | -1.0 | -1.4 | 1.2 | 1.0 | 1.2 | -1.3 | -0.6 | -1.6 | 1.2 | -1.3 | 1.5 | 1.3 | -0.9 | 1.6 | 1.3 | -1.2 | -1.2 | -1.7 |
BMI without tail | 1.2 | 2.6 | 9.0 | 1.9 | -1.8 | 1.8 | -1.8 | -0.1 | 1.8 | -1.1 | -1.8 | 1.8 | 0.2 | 0.7 | -1.6 | 0.5 | -1.7 | 0.5 | 3.0 | -1.7 | -0.3 | 1.5 | -1.5 | 2.0 | 1.5 | -1.9 | 1.2 | -1.7 | -0.2 | -1.9 | 1.8 | 1.1 | 2.9 | -1.5 | 2.9 | 0.0 | -1.8 | 1.9 | 1.4 | -1.8 | 1.4 | 2.0 | 1.7 | -1.7 | -1.8 | -0.1 | 1.9 | 0.1 | 1.5 | -1.8 | 2.1 | -1.6 | -0.1 | 1.8 | -1.4 | -0.9 | 1.8 | 0.0 | 1.2 |
Mean num. licks in bursts | 1.2 | 1.4 | 2.2 | 1.4 | -1.4 | 1.4 | -1.4 | -1.2 | 1.4 | 0.4 | -1.4 | 0.8 | 0.7 | 1.2 | -1.3 | 1.2 | -1.5 | -0.9 | 1.4 | -1.5 | -0.8 | 1.2 | -1.3 | 0.8 | 1.1 | -1.3 | 1.2 | -1.2 | 0.3 | -1.3 | 1.3 | 0.6 | 1.1 | -1.0 | 1.1 | 1.1 | -1.5 | -0.1 | 1.2 | -1.5 | 1.2 | 0.8 | 1.4 | -1.5 | -1.5 | -1.2 | 1.3 | 0.9 | 1.0 | -1.5 | 1.4 | -1.3 | -1.2 | 0.8 | -1.2 | -1.0 | 1.5 | 1.1 | 1.0 |
Reaction time num false alarms | 1.2 | 1.7 | 3.4 | -1.7 | 1.6 | -1.6 | 1.6 | 0.9 | -1.6 | 0.3 | 1.6 | -1.5 | -0.9 | -1.2 | 1.1 | -1.1 | 1.5 | 0.6 | -1.8 | 1.5 | 0.6 | -1.5 | 1.1 | -1.4 | -1.1 | 1.3 | -1.1 | 1.2 | -0.2 | 1.6 | -1.4 | -0.5 | -1.6 | 1.5 | -1.7 | -1.0 | 1.5 | -0.4 | -1.0 | 1.5 | -1.0 | -1.3 | -1.5 | 1.5 | 1.5 | 0.9 | -1.6 | -0.5 | -1.2 | 1.7 | -1.7 | 1.2 | 0.9 | -1.4 | 1.2 | 1.3 | -1.7 | -1.0 | -1.3 |
Social responses | 1.2 | 1.6 | 2.9 | 1.3 | -1.6 | 1.6 | -1.6 | -0.9 | 1.6 | 0.7 | -1.6 | 0.6 | 0.7 | 0.9 | -1.5 | 1.1 | -1.4 | -0.6 | 1.5 | -1.4 | -0.8 | 1.0 | -1.3 | 0.9 | 1.4 | -1.6 | 1.4 | -1.6 | 1.4 | -1.3 | 1.7 | 0.9 | 1.2 | -0.9 | 1.3 | 0.9 | -1.5 | -0.3 | 1.5 | -1.5 | 1.4 | 0.9 | 1.5 | -1.4 | -1.5 | -0.9 | 1.3 | 1.0 | 1.7 | -1.5 | 1.4 | -1.4 | -0.9 | 0.8 | -1.1 | -0.8 | 1.5 | 0.9 | 1.3 |
Intermittent access day 15 total infusions | 1.2 | 1.4 | 4.6 | -0.9 | 0.9 | -0.9 | 0.9 | 1.0 | -0.9 | -2.0 | 0.9 | 1.1 | 0.3 | -1.0 | 0.9 | -1.0 | 1.0 | 1.5 | 0.0 | 1.0 | 2.1 | 0.2 | 0.9 | 1.1 | -2.0 | 1.8 | -2.0 | 1.9 | -2.0 | 0.9 | -1.5 | -1.6 | 0.7 | -0.3 | 0.7 | -1.2 | 0.9 | 1.6 | -0.8 | 0.9 | -0.8 | 1.1 | -0.7 | 1.0 | 1.5 | 1.3 | -1.0 | -2.1 | -0.8 | 0.9 | -0.8 | 0.9 | 1.0 | 1.1 | 0.3 | -0.3 | -0.9 | -1.2 | -0.1 |
Progressive ratio test 1 active lever presses | 1.2 | 1.3 | 4.8 | 0.7 | -0.3 | 0.3 | -0.3 | -0.6 | 0.3 | -2.0 | -0.3 | 2.2 | 2.0 | 0.7 | -0.7 | 0.7 | -0.5 | -0.1 | 1.0 | -0.5 | 1.2 | 1.8 | -0.7 | 2.2 | -1.0 | 0.7 | -1.0 | 0.9 | -1.1 | -0.7 | -0.4 | -1.7 | 1.5 | -2.0 | 1.4 | 0.4 | -0.5 | 0.3 | 0.8 | -0.5 | 0.8 | 2.2 | 0.9 | -0.5 | 0.2 | -0.4 | 0.7 | -1.3 | 0.8 | -0.5 | 0.7 | -0.7 | -0.6 | 2.2 | -1.5 | -1.9 | 0.5 | 0.4 | 1.7 |
Number of responses in last shaping day | 1.2 | 1.2 | 3.0 | -1.1 | 1.3 | -1.3 | 1.3 | 1.0 | -1.3 | -1.4 | 1.3 | 0.2 | -0.1 | -1.0 | 1.1 | -1.0 | 1.2 | 1.1 | -0.9 | 1.2 | 1.6 | -0.4 | 1.1 | 0.3 | -1.7 | 1.7 | -1.7 | 1.7 | -1.3 | 1.1 | -1.5 | -1.5 | -0.3 | 0.2 | -0.4 | -1.0 | 1.2 | 0.6 | -1.0 | 1.2 | -1.0 | 0.3 | -1.1 | 1.2 | 1.6 | 1.1 | -1.1 | -1.6 | -1.0 | 1.2 | -1.1 | 0.9 | 1.0 | 0.3 | 0.6 | 0.3 | -1.2 | -1.0 | -0.5 |
Locomotion distance, session 8 | 1.2 | 1.8 | 5.9 | 1.4 | -1.3 | 1.3 | -1.3 | -0.4 | 1.3 | 0.3 | -1.3 | 0.5 | 0.5 | 0.9 | -1.9 | 0.8 | -1.4 | -0.2 | 1.6 | -1.4 | -0.8 | 0.9 | -1.9 | 0.8 | 1.9 | -2.0 | 1.7 | -2.0 | 2.1 | -1.3 | 2.0 | 1.4 | 1.4 | -0.7 | 1.5 | 0.3 | -1.3 | -0.0 | 2.2 | -1.3 | 2.2 | 0.7 | 1.4 | -1.4 | -1.6 | -0.5 | 1.4 | 0.8 | 2.4 | -1.4 | 1.5 | -1.8 | -0.4 | 0.6 | -1.3 | -0.2 | 1.4 | 0.3 | 1.6 |
Bone: post-yield work | 1.2 | 1.6 | 3.7 | -1.5 | 1.5 | -1.5 | 1.5 | 0.8 | -1.5 | -0.7 | 1.5 | -0.4 | 0.2 | -1.0 | 1.3 | -0.9 | 1.5 | 0.7 | -1.6 | 1.5 | 1.4 | -0.6 | 1.5 | -0.3 | -1.9 | 1.9 | -1.8 | 1.9 | -0.7 | 1.5 | -1.8 | -1.8 | -1.0 | 0.8 | -1.1 | -0.8 | 1.5 | -0.3 | -1.5 | 1.5 | -1.5 | -0.3 | -1.2 | 1.5 | 1.9 | 1.0 | -1.6 | -1.4 | -0.9 | 1.6 | -1.5 | 1.3 | 0.8 | -0.3 | 0.8 | 0.2 | -1.6 | -0.8 | -0.4 |
Delay disc. indifference point, 8s delay | 1.2 | 1.2 | 3.8 | 1.0 | -0.9 | 0.9 | -0.9 | -1.6 | 0.9 | 0.2 | -0.9 | 0.9 | 2.0 | 1.5 | -1.1 | 1.6 | -0.9 | -1.4 | 0.4 | -0.9 | -0.5 | 1.5 | -1.4 | 0.7 | 0.2 | -0.4 | 0.4 | -0.3 | 0.8 | -1.0 | 0.6 | -0.5 | 0.3 | -1.5 | 0.3 | 1.6 | -0.9 | -1.4 | 1.3 | -0.9 | 1.3 | 0.9 | 1.3 | -0.9 | -0.6 | -1.4 | 1.0 | 0.4 | 1.3 | -1.0 | 0.9 | -1.2 | -1.6 | 0.8 | -1.6 | -1.6 | 1.0 | 1.6 | 1.7 |
Distance moved, locomotor task time 2 | 1.2 | 1.4 | 8.3 | 0.1 | -0.4 | 0.4 | -0.4 | 0.9 | 0.4 | -2.1 | -0.4 | 2.2 | 0.2 | -0.7 | -0.5 | -0.7 | -0.4 | 1.9 | 2.1 | -0.4 | 1.7 | 1.0 | -0.8 | 2.2 | 0.0 | -0.3 | -0.3 | -0.2 | -0.9 | -0.2 | 0.5 | -0.4 | 2.7 | -0.8 | 2.7 | -1.2 | -0.5 | 2.9 | 0.8 | -0.5 | 0.8 | 2.5 | 0.6 | -0.4 | -0.2 | 1.2 | 0.2 | -1.5 | 0.9 | -0.5 | 0.8 | -0.6 | 0.9 | 2.2 | -0.9 | -0.5 | 0.5 | -1.2 | 0.9 |
Weight adjusted by age | 1.2 | 1.3 | 5.9 | -0.5 | 0.5 | -0.5 | 0.5 | 0.3 | -0.5 | 2.3 | 0.5 | -2.4 | -1.6 | -0.3 | 0.6 | -0.4 | 0.6 | -0.5 | -1.5 | 0.6 | -1.7 | -1.8 | 0.2 | -2.4 | 1.0 | -0.5 | 1.0 | -0.7 | 1.7 | 0.5 | 0.4 | 1.5 | -2.0 | 1.9 | -1.9 | -0.2 | 0.5 | -1.0 | -0.2 | 0.5 | -0.2 | -2.4 | -0.8 | 0.6 | -0.0 | -0.0 | -0.5 | 1.4 | -0.3 | 0.5 | -0.8 | 0.3 | 0.3 | -2.3 | 1.2 | 1.8 | -0.5 | -0.2 | -1.3 |
Parametrial fat weight | 1.1 | 2.1 | 6.8 | 1.5 | -1.6 | 1.6 | -1.6 | -0.4 | 1.6 | -0.9 | -1.6 | 1.9 | 0.9 | 0.8 | -1.6 | 0.7 | -1.5 | 0.3 | 2.5 | -1.5 | -0.1 | 1.7 | -1.3 | 2.1 | 1.1 | -1.4 | 1.0 | -1.3 | -0.0 | -1.6 | 1.5 | 0.4 | 2.6 | -1.6 | 2.6 | 0.2 | -1.6 | 1.4 | 1.3 | -1.6 | 1.3 | 2.0 | 1.6 | -1.5 | -1.4 | -0.3 | 1.5 | -0.0 | 1.7 | -1.6 | 1.8 | -1.5 | -0.4 | 2.0 | -1.6 | -1.2 | 1.6 | 0.2 | 1.6 |
Pavlov. Cond. change in total contacts | 1.1 | 1.5 | 3.5 | -1.3 | 1.4 | -1.4 | 1.4 | 1.6 | -1.4 | -0.2 | 1.4 | -1.1 | -1.8 | -1.5 | 1.2 | -1.6 | 1.3 | 1.3 | -1.0 | 1.3 | 0.4 | -1.6 | 1.2 | -1.1 | -0.4 | 0.6 | -0.6 | 0.6 | -0.3 | 1.2 | -0.8 | 0.4 | -0.9 | 1.8 | -0.9 | -1.6 | 1.3 | 1.0 | -1.1 | 1.3 | -1.2 | -1.1 | -1.5 | 1.3 | 1.0 | 1.5 | -1.2 | -0.5 | -1.0 | 1.3 | -1.2 | 1.3 | 1.6 | -1.0 | 1.6 | 1.9 | -1.3 | -1.6 | -1.5 |
Intermittent access intake day 1-15 change | 1.1 | 1.1 | 4.3 | 0.3 | -0.7 | 0.7 | -0.7 | -0.3 | 0.7 | -1.5 | -0.7 | 2.1 | 1.6 | 0.2 | -0.2 | 0.5 | -0.3 | 0.3 | 1.0 | -0.3 | 1.6 | 1.6 | -0.1 | 2.1 | -1.2 | 0.9 | -1.1 | 1.0 | -1.5 | -0.3 | -0.5 | -1.6 | 1.5 | -1.9 | 1.5 | 0.6 | -0.4 | 0.7 | 0.2 | -0.4 | 0.2 | 2.1 | 0.7 | -0.3 | 0.3 | -0.1 | 0.3 | -1.6 | 0.2 | -0.5 | 0.5 | 0.0 | -0.3 | 2.1 | -0.9 | -1.7 | 0.5 | 0.6 | 1.2 |
Intermittent access day 15 total locomotion | 1.1 | 1.2 | 3.3 | -1.1 | 0.9 | -0.9 | 0.9 | 1.1 | -0.9 | -1.0 | 0.9 | -0.1 | -1.0 | -1.2 | 1.2 | -1.3 | 1.0 | 1.2 | -0.4 | 1.0 | 1.1 | -0.8 | 1.8 | -0.2 | -1.3 | 1.3 | -1.3 | 1.3 | -1.6 | 1.1 | -1.2 | -0.5 | -0.2 | 0.6 | -0.2 | -1.2 | 1.0 | 1.3 | -1.7 | 1.0 | -1.7 | -0.2 | -1.1 | 1.0 | 1.1 | 1.3 | -1.1 | -1.1 | -1.6 | 1.0 | -1.0 | 1.2 | 1.1 | -0.2 | 1.1 | 0.6 | -1.0 | -1.2 | -1.3 |
Progressive ratio test 1 breakpoint | 1.1 | 1.1 | 4.4 | 0.5 | -0.2 | 0.2 | -0.2 | -0.5 | 0.2 | -2.0 | -0.2 | 2.1 | 1.9 | 0.6 | -0.6 | 0.6 | -0.4 | -0.0 | 0.8 | -0.4 | 1.3 | 1.7 | -0.6 | 2.1 | -1.1 | 0.8 | -1.0 | 1.0 | -1.1 | -0.6 | -0.5 | -1.8 | 1.3 | -1.9 | 1.3 | 0.4 | -0.4 | 0.3 | 0.7 | -0.4 | 0.7 | 2.1 | 0.8 | -0.4 | 0.4 | -0.3 | 0.5 | -1.4 | 0.7 | -0.4 | 0.6 | -0.6 | -0.5 | 2.1 | -1.4 | -1.7 | 0.4 | 0.4 | 1.6 |
Total zone transitions, NPP test | 1.1 | 1.6 | 6.2 | 1.3 | -1.1 | 1.1 | -1.1 | -1.0 | 1.1 | 1.6 | -1.1 | -0.6 | 0.2 | 1.1 | -1.1 | 1.1 | -1.2 | -1.2 | 0.5 | -1.2 | -1.7 | 0.3 | -1.4 | -0.6 | 2.1 | -1.9 | 2.0 | -2.0 | 2.5 | -1.2 | 1.8 | 1.8 | -0.0 | -0.3 | 0.1 | 1.1 | -1.2 | -1.3 | 1.7 | -1.2 | 1.7 | -0.6 | 1.1 | -1.2 | -1.5 | -1.1 | 1.2 | 1.7 | 1.9 | -1.2 | 1.1 | -1.1 | -1.0 | -0.7 | -0.6 | 0.1 | 1.2 | 1.1 | 1.0 |
Bone: endosteal perimeter | 1.1 | 2.2 | 5.0 | -1.7 | 1.8 | -1.8 | 1.8 | 0.7 | -1.8 | 0.3 | 1.8 | -1.3 | -0.8 | -1.1 | 1.5 | -1.0 | 1.7 | 0.2 | -2.2 | 1.7 | 0.6 | -1.5 | 1.5 | -1.6 | -1.5 | 1.7 | -1.3 | 1.6 | -0.4 | 1.7 | -1.7 | -0.8 | -2.1 | 1.8 | -2.1 | -0.7 | 1.7 | -0.6 | -1.7 | 1.7 | -1.7 | -1.7 | -1.7 | 1.7 | 1.7 | 0.8 | -1.6 | -0.4 | -1.5 | 1.7 | -1.8 | 1.5 | 0.7 | -1.4 | 1.4 | 1.2 | -1.7 | -0.7 | -1.4 |
Bone: final moment | 1.1 | 1.7 | 4.5 | -1.4 | 1.5 | -1.5 | 1.5 | 1.2 | -1.5 | 0.6 | 1.5 | -1.6 | -1.5 | -1.2 | 1.4 | -1.3 | 1.4 | 0.8 | -1.6 | 1.4 | 0.2 | -1.7 | 1.4 | -1.3 | -0.8 | 1.0 | -0.8 | 0.9 | -0.1 | 1.4 | -1.1 | -0.2 | -1.5 | 2.1 | -1.5 | -1.2 | 1.5 | 0.0 | -1.4 | 1.5 | -1.4 | -1.4 | -1.6 | 1.4 | 1.2 | 1.1 | -1.5 | -0.3 | -1.3 | 1.5 | -1.5 | 1.4 | 1.2 | -1.4 | 1.6 | 1.6 | -1.5 | -1.2 | -1.6 |
Bone: maximum moment | 1.1 | 1.9 | 4.6 | -1.5 | 1.6 | -1.6 | 1.6 | 1.4 | -1.6 | 0.4 | 1.6 | -1.6 | -1.5 | -1.3 | 1.4 | -1.5 | 1.5 | 1.0 | -1.6 | 1.5 | 0.3 | -1.8 | 1.5 | -1.3 | -0.7 | 1.0 | -0.8 | 0.9 | 0.0 | 1.5 | -1.1 | -0.2 | -1.4 | 2.1 | -1.4 | -1.4 | 1.6 | 0.1 | -1.5 | 1.6 | -1.5 | -1.4 | -1.6 | 1.5 | 1.3 | 1.3 | -1.5 | -0.5 | -1.2 | 1.6 | -1.6 | 1.4 | 1.4 | -1.4 | 1.7 | 1.7 | -1.6 | -1.4 | -1.5 |
Delay disc. indifference point, 4s delay | 1.1 | 1.2 | 2.6 | 0.9 | -1.3 | 1.3 | -1.3 | -1.4 | 1.3 | 1.2 | -1.3 | 0.3 | 1.3 | 1.1 | -0.8 | 1.4 | -0.9 | -1.4 | 0.5 | -0.9 | -0.9 | 0.9 | -1.2 | 0.5 | 0.9 | -0.9 | 1.0 | -0.9 | 1.1 | -0.9 | 1.0 | 0.0 | 0.2 | -1.0 | 0.3 | 1.6 | -1.2 | -1.1 | 1.1 | -1.2 | 1.1 | 0.3 | 1.2 | -0.9 | -1.0 | -1.3 | 0.9 | 0.9 | 1.1 | -1.3 | 0.8 | -1.0 | -1.4 | 0.8 | -1.0 | -1.3 | 1.3 | 1.6 | 1.2 |
Delay discount exponential model param | 1.1 | 1.2 | 2.0 | -1.1 | 1.1 | -1.1 | 1.1 | 1.4 | -1.1 | -0.5 | 1.1 | -0.8 | -1.4 | -1.4 | 1.1 | -1.4 | 1.1 | 1.3 | -0.6 | 1.1 | 0.7 | -1.2 | 1.4 | -0.6 | -0.7 | 0.8 | -0.8 | 0.8 | -0.9 | 1.1 | -0.9 | -0.0 | -0.5 | 1.2 | -0.5 | -1.4 | 1.0 | 1.0 | -1.3 | 1.0 | -1.3 | -0.8 | -1.3 | 1.1 | 1.0 | 1.3 | -1.1 | -0.7 | -1.3 | 1.2 | -1.0 | 1.3 | 1.4 | -0.7 | 1.4 | 1.2 | -1.2 | -1.4 | -1.4 |
Delay discount hyperbolic model param | 1.1 | 1.2 | 2.0 | -1.1 | 1.2 | -1.2 | 1.2 | 1.4 | -1.2 | -0.5 | 1.2 | -0.7 | -1.4 | -1.3 | 1.1 | -1.4 | 1.1 | 1.2 | -0.7 | 1.1 | 0.7 | -1.2 | 1.4 | -0.6 | -0.8 | 0.9 | -0.9 | 0.9 | -1.0 | 1.1 | -1.0 | -0.1 | -0.5 | 1.2 | -0.5 | -1.4 | 1.1 | 0.9 | -1.4 | 1.1 | -1.4 | -0.8 | -1.3 | 1.1 | 1.0 | 1.3 | -1.1 | -0.7 | -1.3 | 1.2 | -1.1 | 1.3 | 1.4 | -0.7 | 1.3 | 1.2 | -1.2 | -1.4 | -1.4 |
Bouts of movement, locomotor time 1 | 1.1 | 1.2 | 5.9 | 0.5 | -0.8 | 0.8 | -0.8 | -1.6 | 0.8 | -0.2 | -0.8 | 1.1 | 2.4 | 1.3 | -0.5 | 1.6 | -0.7 | -1.4 | 0.3 | -0.7 | 0.4 | 1.7 | -0.8 | 1.5 | -0.8 | 0.5 | -0.4 | 0.5 | -0.5 | -0.5 | -0.2 | -1.6 | 0.4 | -2.0 | 0.4 | 1.8 | -0.9 | -1.5 | 0.5 | -0.9 | 0.5 | 1.3 | 1.1 | -0.7 | -0.1 | -1.5 | 0.6 | -0.2 | 0.6 | -0.9 | 0.6 | -0.5 | -1.6 | 1.3 | -1.5 | -2.3 | 0.9 | 1.8 | 1.6 |
Vertical activity count, locomotor time 1 | 1.1 | 1.1 | 6.5 | -1.0 | 0.6 | -0.6 | 0.6 | 1.9 | -0.6 | -0.5 | 0.6 | 0.0 | -2.0 | -1.7 | 0.7 | -1.7 | 0.8 | 2.0 | 0.5 | 0.8 | 1.0 | -1.1 | 0.7 | -0.2 | 0.1 | -0.0 | -0.3 | -0.0 | -0.7 | 0.9 | -0.1 | 0.7 | 0.6 | 1.4 | 0.6 | -1.9 | 0.5 | 2.6 | -0.8 | 0.5 | -0.7 | -0.2 | -0.9 | 0.8 | 0.4 | 1.9 | -0.9 | -0.8 | -0.9 | 0.5 | -0.6 | 0.7 | 1.9 | -0.1 | 1.2 | 1.4 | -0.5 | -1.9 | -1.4 |
Latency to leave start box in cocaine runway, M | 1.1 | 1.1 | 3.0 | 1.0 | -1.1 | 1.1 | -1.1 | -1.0 | 1.1 | 1.6 | -1.1 | -0.4 | -0.2 | 1.0 | -0.9 | 1.0 | -1.1 | -1.3 | 0.4 | -1.1 | -1.7 | 0.1 | -0.7 | -0.7 | 1.6 | -1.5 | 1.6 | -1.6 | 1.5 | -1.0 | 1.4 | 1.5 | -0.2 | -0.1 | -0.1 | 1.1 | -1.1 | -0.9 | 0.6 | -1.1 | 0.6 | -0.6 | 0.8 | -1.1 | -1.4 | -1.1 | 1.0 | 1.7 | 0.8 | -1.1 | 0.9 | -0.7 | -1.0 | -0.5 | -0.2 | 0.0 | 1.1 | 1.1 | 0.3 |
Delay discounting water rate 12 sec | 1.0 | 1.5 | 5.2 | -1.0 | 1.1 | -1.1 | 1.1 | 1.3 | -1.1 | -1.2 | 1.1 | 0.6 | -0.6 | -1.2 | 1.5 | -1.3 | 1.1 | 1.4 | -0.5 | 1.1 | 1.5 | -0.5 | 1.3 | 0.3 | -1.6 | 1.6 | -1.7 | 1.7 | -2.3 | 1.1 | -1.6 | -1.3 | -0.0 | 0.6 | -0.1 | -1.2 | 1.3 | 1.6 | -1.5 | 1.3 | -1.4 | 0.3 | -1.2 | 1.1 | 1.4 | 1.4 | -1.1 | -1.6 | -1.8 | 1.3 | -1.1 | 1.2 | 1.3 | 0.4 | 0.8 | 0.4 | -1.3 | -1.2 | -1.2 |
Delay discounting water rate 18 sec | 1.0 | 1.3 | 3.6 | -1.2 | 1.0 | -1.0 | 1.0 | 1.4 | -1.0 | -0.7 | 1.0 | 0.1 | -1.2 | -1.4 | 1.1 | -1.5 | 1.1 | 1.4 | -0.5 | 1.1 | 1.2 | -0.9 | 1.2 | -0.1 | -1.1 | 1.2 | -1.2 | 1.2 | -1.9 | 1.2 | -1.3 | -0.7 | -0.2 | 1.0 | -0.2 | -1.4 | 1.1 | 1.8 | -1.5 | 1.1 | -1.5 | -0.1 | -1.3 | 1.1 | 1.1 | 1.4 | -1.1 | -1.1 | -1.7 | 1.3 | -1.1 | 1.1 | 1.4 | 0.1 | 1.0 | 1.0 | -1.3 | -1.4 | -1.5 |
Light reinforcement 1 | 1.0 | 1.7 | 2.8 | 1.4 | -1.6 | 1.6 | -1.6 | -1.2 | 1.6 | -0.1 | -1.6 | 1.5 | 1.1 | 1.1 | -1.3 | 1.3 | -1.6 | -0.8 | 1.6 | -1.6 | -0.5 | 1.5 | -1.0 | 1.3 | 1.1 | -1.3 | 1.2 | -1.3 | 0.3 | -1.4 | 1.3 | 0.3 | 1.5 | -1.7 | 1.5 | 1.1 | -1.6 | 0.3 | 1.1 | -1.6 | 1.1 | 1.2 | 1.6 | -1.6 | -1.5 | -1.2 | 1.4 | 0.7 | 1.4 | -1.6 | 1.6 | -1.2 | -1.2 | 1.5 | -1.3 | -1.3 | 1.6 | 1.1 | 1.4 |
Reaction time number correct | 1.0 | 1.5 | 4.1 | -1.1 | 1.3 | -1.3 | 1.3 | 1.1 | -1.3 | 0.8 | 1.3 | -1.5 | -1.9 | -1.2 | 1.3 | -1.3 | 1.1 | 0.7 | -1.3 | 1.1 | -0.1 | -1.8 | 1.1 | -1.6 | -0.3 | 0.6 | -0.4 | 0.5 | -0.1 | 1.2 | -0.7 | 0.7 | -1.4 | 2.0 | -1.4 | -1.2 | 1.2 | 0.5 | -1.2 | 1.2 | -1.2 | -1.7 | -1.5 | 1.1 | 0.8 | 1.0 | -1.1 | 0.2 | -1.3 | 1.2 | -1.3 | 1.1 | 1.1 | -1.5 | 1.6 | 1.9 | -1.2 | -1.2 | -1.8 |
Reaction time trials correct on left | 1.0 | 1.5 | 4.1 | -1.1 | 1.3 | -1.3 | 1.3 | 1.1 | -1.3 | 0.8 | 1.3 | -1.5 | -1.9 | -1.2 | 1.3 | -1.3 | 1.1 | 0.7 | -1.3 | 1.1 | -0.1 | -1.8 | 1.1 | -1.6 | -0.3 | 0.6 | -0.4 | 0.5 | -0.1 | 1.2 | -0.7 | 0.7 | -1.4 | 2.0 | -1.4 | -1.2 | 1.2 | 0.5 | -1.2 | 1.2 | -1.2 | -1.7 | -1.5 | 1.1 | 0.8 | 1.0 | -1.1 | 0.2 | -1.3 | 1.2 | -1.3 | 1.1 | 1.1 | -1.5 | 1.6 | 1.9 | -1.2 | -1.2 | -1.8 |
Reaction time trials on left | 1.0 | 1.4 | 4.1 | -1.1 | 1.2 | -1.2 | 1.2 | 1.1 | -1.2 | 0.9 | 1.2 | -1.6 | -1.9 | -1.2 | 1.3 | -1.3 | 1.1 | 0.7 | -1.3 | 1.1 | -0.2 | -1.8 | 1.1 | -1.7 | -0.2 | 0.5 | -0.3 | 0.4 | -0.0 | 1.1 | -0.7 | 0.7 | -1.4 | 2.0 | -1.4 | -1.1 | 1.1 | 0.4 | -1.1 | 1.1 | -1.1 | -1.8 | -1.4 | 1.1 | 0.8 | 0.9 | -1.1 | 0.3 | -1.2 | 1.1 | -1.2 | 1.1 | 1.1 | -1.5 | 1.6 | 1.9 | -1.1 | -1.1 | -1.8 |
Reaction time trials completed | 1.0 | 1.4 | 4.1 | -1.1 | 1.2 | -1.2 | 1.2 | 1.1 | -1.2 | 0.9 | 1.2 | -1.6 | -1.9 | -1.2 | 1.3 | -1.3 | 1.1 | 0.7 | -1.3 | 1.1 | -0.2 | -1.8 | 1.1 | -1.7 | -0.2 | 0.5 | -0.3 | 0.4 | -0.0 | 1.1 | -0.7 | 0.7 | -1.4 | 2.0 | -1.4 | -1.1 | 1.1 | 0.4 | -1.1 | 1.1 | -1.1 | -1.8 | -1.4 | 1.1 | 0.8 | 0.9 | -1.1 | 0.3 | -1.2 | 1.1 | -1.2 | 1.1 | 1.1 | -1.5 | 1.6 | 1.9 | -1.1 | -1.1 | -1.8 |
Reaction time trials AUC | 1.0 | 1.4 | 4.2 | -1.0 | 1.2 | -1.2 | 1.2 | 1.0 | -1.2 | 1.0 | 1.2 | -1.6 | -2.0 | -1.1 | 1.2 | -1.2 | 1.0 | 0.6 | -1.2 | 1.0 | -0.3 | -1.8 | 1.0 | -1.7 | -0.1 | 0.4 | -0.2 | 0.3 | 0.1 | 1.0 | -0.6 | 0.8 | -1.4 | 2.0 | -1.4 | -1.1 | 1.0 | 0.4 | -1.1 | 1.0 | -1.0 | -1.8 | -1.4 | 1.0 | 0.7 | 0.9 | -1.0 | 0.4 | -1.2 | 1.1 | -1.1 | 1.0 | 1.0 | -1.5 | 1.6 | 2.0 | -1.1 | -1.1 | -1.8 |
Cocaine response after cond. corrected | 1.0 | 1.1 | 4.4 | -0.5 | 0.7 | -0.7 | 0.7 | 1.3 | -0.7 | -2.1 | 0.7 | 0.9 | -0.5 | -1.2 | 0.8 | -1.2 | 0.7 | 1.8 | 0.5 | 0.7 | 1.6 | -0.0 | 1.1 | 1.2 | -1.1 | 1.0 | -1.3 | 1.1 | -2.0 | 0.6 | -1.0 | -0.9 | 1.0 | -0.1 | 1.0 | -1.4 | 0.7 | 2.0 | -1.1 | 0.7 | -1.1 | 1.2 | -0.6 | 0.7 | 0.9 | 1.4 | -0.6 | -1.7 | -1.1 | 0.7 | -0.5 | 1.0 | 1.3 | 1.0 | 0.6 | 0.1 | -0.7 | -1.4 | -0.6 |
Conditioned locomotion | 1.0 | 1.2 | 2.3 | -1.2 | 1.1 | -1.1 | 1.1 | 1.3 | -1.1 | -0.8 | 1.1 | -0.1 | -0.8 | -1.3 | 1.2 | -1.4 | 1.1 | 1.4 | -0.5 | 1.1 | 1.2 | -0.8 | 1.2 | -0.1 | -1.2 | 1.1 | -1.3 | 1.1 | -1.0 | 1.2 | -1.2 | -0.6 | -0.1 | 0.9 | -0.1 | -1.5 | 1.2 | 1.3 | -1.1 | 1.2 | -1.1 | -0.1 | -1.1 | 1.1 | 1.2 | 1.5 | -1.2 | -1.2 | -1.0 | 1.2 | -1.0 | 1.1 | 1.3 | -0.1 | 1.1 | 0.8 | -1.2 | -1.5 | -0.9 |
Short access day 10 total locomotion | 1.0 | 1.0 | 2.4 | 1.1 | -1.0 | 1.0 | -1.0 | -1.3 | 1.0 | 0.0 | -1.0 | 0.9 | 1.2 | 1.1 | -1.0 | 1.4 | -1.1 | -1.3 | 0.6 | -1.1 | -0.6 | 1.2 | -0.7 | 0.8 | 0.6 | -0.6 | 0.8 | -0.6 | 0.5 | -1.1 | 0.8 | -0.2 | 0.4 | -1.4 | 0.4 | 1.4 | -1.2 | -1.2 | 0.8 | -1.2 | 0.8 | 0.8 | 1.2 | -1.1 | -0.9 | -1.5 | 1.1 | 0.7 | 0.8 | -1.2 | 1.1 | -0.9 | -1.3 | 0.8 | -1.1 | -1.3 | 1.2 | 1.4 | 1.1 |
Locomotion velocity, session 2 | 1.0 | 1.2 | 3.0 | 1.1 | -1.1 | 1.1 | -1.1 | -0.7 | 1.1 | 0.9 | -1.1 | -0.3 | 0.2 | 1.0 | -1.1 | 0.9 | -1.2 | -0.8 | 0.9 | -1.2 | -1.2 | 0.5 | -1.3 | -0.0 | 1.6 | -1.6 | 1.6 | -1.7 | 1.7 | -1.2 | 1.6 | 1.4 | 0.5 | -0.2 | 0.6 | 0.8 | -1.1 | -0.8 | 1.4 | -1.1 | 1.4 | -0.0 | 1.1 | -1.2 | -1.5 | -0.9 | 1.3 | 1.3 | 1.6 | -1.2 | 1.2 | -1.2 | -0.7 | -0.2 | -0.7 | -0.1 | 1.2 | 0.8 | 0.9 |
Total zone transitions, hab. session 1 | 1.0 | 1.4 | 7.0 | 0.9 | -0.7 | 0.7 | -0.7 | -0.4 | 0.7 | 1.9 | -0.7 | -1.3 | -0.8 | 0.7 | -1.3 | 0.5 | -0.7 | -0.8 | 0.2 | -0.7 | -1.9 | -0.5 | -1.3 | -1.2 | 2.3 | -2.0 | 2.1 | -2.1 | 2.6 | -0.8 | 1.8 | 2.4 | -0.4 | 0.6 | -0.3 | 0.4 | -0.7 | -1.1 | 1.5 | -0.7 | 1.6 | -1.3 | 0.5 | -0.7 | -1.3 | -0.5 | 0.8 | 1.8 | 1.5 | -0.7 | 0.7 | -1.2 | -0.4 | -1.4 | -0.1 | 1.1 | 0.7 | 0.4 | 0.2 |
Reaction time num false alarms AUC | 0.9 | 1.2 | 3.2 | -1.4 | 1.3 | -1.3 | 1.3 | 0.5 | -1.3 | 0.4 | 1.3 | -1.4 | -0.5 | -0.8 | 0.9 | -0.7 | 1.2 | 0.1 | -1.8 | 1.2 | 0.4 | -1.2 | 0.9 | -1.3 | -1.0 | 1.2 | -0.9 | 1.1 | 0.1 | 1.4 | -1.2 | -0.5 | -1.7 | 1.2 | -1.7 | -0.5 | 1.2 | -1.0 | -0.8 | 1.2 | -0.8 | -1.3 | -1.2 | 1.2 | 1.2 | 0.5 | -1.3 | -0.3 | -1.0 | 1.4 | -1.4 | 1.0 | 0.5 | -1.4 | 1.0 | 0.9 | -1.4 | -0.5 | -0.9 |
Cocaine induced anxiety | 0.9 | 1.1 | 2.1 | 1.1 | -1.1 | 1.1 | -1.1 | -1.2 | 1.1 | -0.0 | -1.1 | 0.8 | 1.2 | 1.2 | -1.1 | 1.3 | -1.1 | -1.0 | 0.8 | -1.1 | -0.5 | 1.2 | -1.1 | 0.9 | 0.7 | -0.7 | 0.8 | -0.7 | 0.6 | -1.1 | 0.9 | 0.0 | 0.7 | -1.4 | 0.7 | 1.3 | -1.1 | -0.8 | 1.1 | -1.1 | 1.1 | 0.9 | 1.2 | -1.1 | -1.0 | -1.2 | 1.1 | 0.5 | 1.1 | -1.1 | 1.1 | -1.1 | -1.2 | 0.9 | -1.3 | -1.2 | 1.1 | 1.3 | 1.3 |
Incentive Sensitization - Responses | 0.9 | 0.9 | 1.9 | -1.0 | 0.7 | -0.7 | 0.7 | 1.2 | -0.7 | 0.1 | 0.7 | -0.8 | -1.3 | -1.2 | 1.0 | -1.3 | 1.0 | 1.2 | -0.4 | 1.0 | 0.5 | -1.2 | 1.2 | -0.8 | -0.6 | 0.6 | -0.7 | 0.5 | -0.4 | 1.0 | -0.7 | 0.3 | -0.3 | 1.4 | -0.3 | -1.3 | 1.0 | 1.2 | -1.1 | 1.0 | -1.1 | -0.8 | -1.0 | 1.0 | 0.8 | 1.4 | -1.0 | -0.5 | -1.1 | 1.0 | -0.9 | 0.9 | 1.2 | -0.8 | 1.2 | 1.2 | -1.0 | -1.3 | -1.3 |
Stereotopy head waving duration, day 7 | 0.9 | 1.1 | 2.5 | 1.2 | -1.1 | 1.1 | -1.1 | -0.3 | 1.1 | -0.0 | -1.1 | 0.8 | 0.7 | 0.9 | -1.4 | 0.7 | -1.0 | -0.1 | 1.3 | -1.0 | -0.5 | 0.9 | -1.6 | 0.9 | 1.3 | -1.3 | 1.0 | -1.2 | 1.0 | -1.1 | 1.3 | 0.6 | 1.2 | -0.8 | 1.3 | 0.4 | -1.0 | 0.3 | 1.5 | -1.0 | 1.5 | 0.9 | 1.1 | -1.0 | -1.1 | -0.4 | 1.2 | 0.4 | 1.6 | -1.0 | 1.2 | -1.6 | -0.3 | 0.9 | -1.3 | -0.6 | 1.0 | 0.4 | 1.2 |
Degree of sensitization stereotypy | 0.9 | 0.9 | 3.0 | 1.0 | -0.9 | 0.9 | -0.9 | -0.1 | 0.9 | -0.1 | -0.9 | 0.6 | 0.5 | 0.6 | -1.3 | 0.4 | -0.9 | 0.1 | 1.3 | -0.9 | -0.4 | 0.7 | -1.6 | 0.8 | 1.3 | -1.3 | 1.0 | -1.3 | 1.3 | -0.9 | 1.4 | 0.7 | 1.2 | -0.5 | 1.3 | 0.1 | -0.9 | 0.3 | 1.7 | -0.9 | 1.7 | 0.8 | 1.0 | -0.9 | -0.9 | -0.1 | 1.1 | 0.3 | 1.7 | -0.9 | 1.1 | -1.5 | -0.1 | 0.7 | -1.2 | -0.3 | 0.9 | 0.1 | 1.2 |
Bone: final force | 0.9 | 1.4 | 4.6 | -1.2 | 1.3 | -1.3 | 1.3 | 0.9 | -1.3 | 1.0 | 1.3 | -1.8 | -1.4 | -1.0 | 1.2 | -1.1 | 1.2 | 0.5 | -1.5 | 1.2 | -0.1 | -1.6 | 1.1 | -1.5 | -0.4 | 0.7 | -0.5 | 0.6 | 0.3 | 1.2 | -0.8 | 0.0 | -1.5 | 2.1 | -1.5 | -0.9 | 1.3 | -0.3 | -1.1 | 1.3 | -1.1 | -1.5 | -1.4 | 1.2 | 1.0 | 0.8 | -1.2 | 0.0 | -1.1 | 1.3 | -1.3 | 1.2 | 0.9 | -1.6 | 1.5 | 1.6 | -1.3 | -0.9 | -1.5 |
Bone: maximum force | 0.9 | 1.5 | 4.6 | -1.3 | 1.3 | -1.3 | 1.3 | 1.1 | -1.3 | 0.8 | 1.3 | -1.8 | -1.4 | -1.1 | 1.2 | -1.2 | 1.3 | 0.6 | -1.6 | 1.3 | -0.1 | -1.7 | 1.2 | -1.5 | -0.4 | 0.7 | -0.5 | 0.6 | 0.5 | 1.3 | -0.8 | 0.1 | -1.5 | 2.2 | -1.5 | -1.1 | 1.3 | -0.2 | -1.2 | 1.3 | -1.2 | -1.5 | -1.4 | 1.3 | 1.0 | 1.0 | -1.3 | -0.1 | -0.9 | 1.3 | -1.4 | 1.2 | 1.1 | -1.6 | 1.5 | 1.7 | -1.3 | -1.1 | -1.4 |
Left kidney weight | 0.8 | 2.4 | 10.7 | 1.0 | -0.8 | 0.8 | -0.8 | 0.4 | 0.8 | -2.8 | -0.8 | 3.2 | 1.4 | 0.2 | -1.0 | -0.0 | -0.9 | 1.4 | 2.6 | -0.9 | 1.8 | 2.0 | -1.3 | 3.1 | -0.2 | -0.2 | -0.5 | -0.1 | -1.3 | -0.9 | 0.4 | -1.1 | 3.3 | -1.8 | 3.3 | -0.8 | -0.7 | 2.6 | 1.3 | -0.7 | 1.2 | 3.0 | 1.2 | -0.9 | -0.3 | 0.7 | 0.9 | -1.7 | 1.4 | -0.7 | 1.4 | -1.2 | 0.4 | 3.0 | -1.6 | -1.4 | 0.7 | -0.8 | 1.9 |
Incentive Sensitization - Breakpoint | 0.8 | 0.8 | 1.9 | -1.0 | 0.6 | -0.6 | 0.6 | 1.1 | -0.6 | -0.1 | 0.6 | -0.6 | -1.2 | -1.2 | 1.0 | -1.3 | 0.9 | 1.2 | -0.3 | 0.9 | 0.6 | -1.1 | 1.2 | -0.6 | -0.7 | 0.6 | -0.8 | 0.6 | -0.6 | 1.0 | -0.7 | 0.2 | -0.1 | 1.2 | -0.1 | -1.3 | 1.0 | 1.3 | -1.1 | 1.0 | -1.1 | -0.6 | -1.0 | 0.9 | 0.8 | 1.4 | -1.0 | -0.6 | -1.1 | 0.9 | -0.9 | 0.9 | 1.1 | -0.6 | 1.1 | 1.0 | -0.9 | -1.3 | -1.2 |
Short access day 1 total inactive lever presses | 0.8 | 0.9 | 3.1 | 0.9 | -0.9 | 0.9 | -0.9 | -0.7 | 0.9 | -1.3 | -0.9 | 1.7 | 1.3 | 0.8 | -1.0 | 0.7 | -0.8 | -0.1 | 1.3 | -0.8 | 0.6 | 1.5 | -0.4 | 1.7 | -0.5 | 0.1 | -0.4 | 0.3 | -1.0 | -0.9 | 0.1 | -0.8 | 1.5 | -1.8 | 1.5 | 0.6 | -0.8 | 0.6 | 0.4 | -0.8 | 0.4 | 1.7 | 1.0 | -0.8 | -0.3 | -0.4 | 0.9 | -0.7 | 0.4 | -0.8 | 0.9 | -0.6 | -0.7 | 1.7 | -1.2 | -1.5 | 0.8 | 0.6 | 1.1 |
Vertical activity count, locomotor time 2 | 0.8 | 0.9 | 5.9 | 0.3 | -0.6 | 0.6 | -0.6 | 0.8 | 0.6 | -1.0 | -0.6 | 1.3 | -0.7 | -0.6 | -0.6 | -0.6 | -0.5 | 1.5 | 1.9 | -0.5 | 0.9 | 0.4 | -0.8 | 1.1 | 0.8 | -0.9 | 0.4 | -0.9 | -0.4 | -0.3 | 0.9 | 0.7 | 2.1 | -0.2 | 2.1 | -1.1 | -0.7 | 2.4 | 0.6 | -0.7 | 0.6 | 1.4 | 0.5 | -0.5 | -0.7 | 1.0 | 0.3 | -0.6 | 0.7 | -0.6 | 0.8 | -0.6 | 0.8 | 1.1 | -0.3 | 0.2 | 0.6 | -1.1 | 0.3 |
Mn content in liver | 0.8 | 1.0 | 2.7 | 1.0 | -1.0 | 1.0 | -1.0 | -0.9 | 1.0 | 0.7 | -1.0 | 0.0 | 0.7 | 1.0 | -1.0 | 1.1 | -1.0 | -0.9 | 0.7 | -1.0 | -1.0 | 0.7 | -1.1 | 0.2 | 1.3 | -1.3 | 1.2 | -1.3 | 1.6 | -1.0 | 1.3 | 0.6 | 0.4 | -0.2 | 0.5 | 0.9 | -1.0 | -1.0 | 1.1 | -1.0 | 1.1 | 0.2 | 1.1 | -1.0 | -1.1 | -1.0 | 1.0 | 1.0 | 1.6 | -1.0 | 1.0 | -1.1 | -0.9 | 0.1 | -0.9 | -0.5 | 1.0 | 0.9 | 1.2 |
Epididymis fat weight | 0.7 | 1.7 | 4.2 | 1.4 | -1.4 | 1.4 | -1.4 | -1.4 | 1.4 | -0.6 | -1.4 | 1.6 | 1.8 | 1.4 | -1.1 | 1.5 | -1.4 | -1.1 | 1.3 | -1.4 | -0.3 | 1.9 | -1.2 | 1.6 | 0.2 | -0.6 | 0.4 | -0.5 | 0.2 | -1.4 | 0.8 | -0.5 | 1.3 | -2.1 | 1.3 | 1.4 | -1.5 | -0.4 | 1.1 | -1.5 | 1.0 | 1.5 | 1.6 | -1.4 | -0.9 | -1.3 | 1.4 | 0.2 | 1.3 | -1.5 | 1.4 | -1.0 | -1.4 | 1.7 | -1.6 | -1.9 | 1.5 | 1.4 | 1.8 |
Tail length | 0.7 | 2.0 | 4.1 | 1.6 | -1.5 | 1.5 | -1.5 | -0.8 | 1.5 | -0.7 | -1.5 | 1.7 | 1.3 | 1.2 | -1.6 | 1.1 | -1.5 | -0.3 | 2.0 | -1.5 | -0.3 | 1.7 | -1.7 | 1.7 | 1.0 | -1.3 | 0.9 | -1.2 | 0.4 | -1.6 | 1.4 | 0.3 | 2.0 | -1.7 | 2.0 | 0.7 | -1.5 | 0.6 | 1.8 | -1.5 | 1.8 | 1.7 | 1.6 | -1.5 | -1.3 | -0.8 | 1.6 | 0.2 | 1.8 | -1.5 | 1.7 | -1.7 | -0.8 | 1.6 | -1.7 | -1.3 | 1.5 | 0.7 | 1.8 |
Liver weight, left | 0.7 | 1.1 | 3.0 | 1.1 | -1.2 | 1.2 | -1.2 | -0.9 | 1.2 | 1.2 | -1.2 | -0.4 | -0.2 | 0.9 | -0.9 | 0.9 | -1.2 | -1.0 | 0.8 | -1.2 | -1.5 | 0.3 | -0.9 | -0.3 | 1.7 | -1.7 | 1.7 | -1.7 | 1.2 | -1.2 | 1.5 | 1.4 | 0.2 | -0.3 | 0.3 | 0.9 | -1.1 | -0.5 | 0.8 | -1.1 | 0.9 | -0.3 | 0.9 | -1.2 | -1.6 | -1.0 | 1.1 | 1.5 | 0.9 | -1.1 | 1.1 | -1.0 | -0.9 | -0.3 | -0.5 | -0.0 | 1.1 | 0.9 | 0.3 |
Pavlov. Cond. lever latency | 0.7 | 1.0 | 2.6 | 0.9 | -1.0 | 1.0 | -1.0 | -1.2 | 1.0 | 1.6 | -1.0 | -0.8 | 0.1 | 1.0 | -0.6 | 1.1 | -1.0 | -1.4 | 0.2 | -1.0 | -1.6 | 0.2 | -0.5 | -0.7 | 1.4 | -1.3 | 1.5 | -1.4 | 1.3 | -0.9 | 1.1 | 1.3 | -0.4 | -0.4 | -0.4 | 1.3 | -1.0 | -1.4 | 0.5 | -1.0 | 0.6 | -0.7 | 0.8 | -1.0 | -1.3 | -1.3 | 0.9 | 1.6 | 0.7 | -1.0 | 0.7 | -0.6 | -1.2 | -0.9 | -0.2 | -0.2 | 1.0 | 1.3 | 0.3 |
Pavlov. Cond. response bias | 0.7 | 0.9 | 2.1 | -1.0 | 1.1 | -1.1 | 1.1 | 1.4 | -1.1 | -0.9 | 1.1 | -0.1 | -1.1 | -1.2 | 0.8 | -1.3 | 1.0 | 1.4 | -0.4 | 1.0 | 0.9 | -0.9 | 0.8 | -0.2 | -0.7 | 0.8 | -0.9 | 0.8 | -0.7 | 1.0 | -0.8 | -0.2 | -0.1 | 1.1 | -0.1 | -1.5 | 1.1 | 1.3 | -0.8 | 1.1 | -0.9 | -0.2 | -1.1 | 1.0 | 1.0 | 1.4 | -0.9 | -0.9 | -0.9 | 1.1 | -0.8 | 0.8 | 1.4 | -0.1 | 0.9 | 1.1 | -1.1 | -1.5 | -1.0 |
Intermittent access intake escalation | 0.7 | 0.7 | 2.8 | 0.2 | -0.5 | 0.5 | -0.5 | -0.3 | 0.5 | -1.4 | -0.5 | 1.7 | 1.2 | 0.1 | -0.1 | 0.4 | -0.3 | 0.2 | 0.8 | -0.3 | 1.3 | 1.3 | 0.0 | 1.7 | -1.0 | 0.7 | -0.9 | 0.8 | -1.3 | -0.2 | -0.5 | -1.4 | 1.2 | -1.6 | 1.1 | 0.5 | -0.3 | 0.5 | 0.0 | -0.3 | 0.0 | 1.7 | 0.5 | -0.3 | 0.3 | -0.2 | 0.2 | -1.3 | 0.1 | -0.4 | 0.4 | 0.2 | -0.3 | 1.7 | -0.7 | -1.4 | 0.4 | 0.5 | 0.9 |
Intermittent access total infusions | 0.7 | 0.7 | 2.7 | -0.6 | 0.7 | -0.7 | 0.7 | 0.7 | -0.7 | -1.5 | 0.7 | 0.9 | 0.5 | -0.6 | 0.6 | -0.7 | 0.7 | 1.1 | -0.0 | 0.7 | 1.6 | 0.2 | 0.4 | 0.9 | -1.5 | 1.3 | -1.5 | 1.4 | -1.3 | 0.6 | -1.1 | -1.4 | 0.6 | -0.3 | 0.5 | -0.9 | 0.7 | 1.1 | -0.3 | 0.7 | -0.3 | 0.9 | -0.4 | 0.7 | 1.2 | 0.9 | -0.6 | -1.7 | -0.2 | 0.7 | -0.5 | 0.5 | 0.7 | 0.9 | 0.0 | -0.3 | -0.7 | -0.9 | 0.2 |
Intermittent access standard deviation | 0.7 | 0.7 | 2.9 | -0.0 | -0.0 | 0.0 | -0.0 | 0.0 | 0.0 | -1.5 | -0.0 | 1.7 | 1.4 | 0.0 | 0.1 | 0.1 | 0.0 | 0.6 | 0.6 | 0.0 | 1.6 | 1.2 | -0.4 | 1.7 | -1.1 | 0.9 | -1.1 | 1.0 | -1.1 | 0.0 | -0.7 | -1.7 | 1.2 | -1.3 | 1.1 | -0.0 | 0.0 | 0.7 | 0.4 | 0.0 | 0.4 | 1.7 | 0.3 | 0.0 | 0.6 | 0.2 | -0.0 | -1.6 | 0.5 | 0.1 | 0.2 | -0.1 | 0.0 | 1.7 | -0.9 | -1.2 | -0.1 | -0.0 | 1.2 |
Lifetime Intake | 0.7 | 0.8 | 3.2 | -0.6 | 0.7 | -0.7 | 0.7 | 0.6 | -0.7 | -1.7 | 0.7 | 1.1 | 0.7 | -0.5 | 0.5 | -0.6 | 0.6 | 1.0 | -0.0 | 0.6 | 1.7 | 0.4 | 0.3 | 1.1 | -1.6 | 1.4 | -1.6 | 1.5 | -1.4 | 0.5 | -1.2 | -1.6 | 0.6 | -0.5 | 0.6 | -0.8 | 0.6 | 1.0 | -0.3 | 0.6 | -0.3 | 1.1 | -0.4 | 0.6 | 1.2 | 0.8 | -0.6 | -1.8 | -0.2 | 0.7 | -0.5 | 0.5 | 0.6 | 1.1 | -0.1 | -0.5 | -0.7 | -0.8 | 0.4 |
Short access day 1 total infusions | 0.7 | 0.7 | 4.3 | -0.5 | 0.7 | -0.7 | 0.7 | 0.2 | -0.7 | -1.5 | 0.7 | 0.9 | 0.8 | -0.3 | 0.5 | -0.0 | 0.6 | 0.2 | -0.8 | 0.6 | 1.4 | 0.5 | 0.7 | 0.9 | -1.5 | 1.6 | -1.5 | 1.7 | -1.6 | 0.5 | -1.4 | -2.1 | -0.3 | -0.9 | -0.4 | 0.2 | 0.6 | -0.4 | -0.7 | 0.6 | -0.7 | 0.9 | -0.4 | 0.6 | 1.2 | -0.1 | -0.5 | -1.5 | -0.6 | 0.6 | -0.6 | 0.5 | 0.2 | 0.9 | -0.2 | -0.7 | -0.6 | 0.2 | 0.2 |
Time in novel zone, hab. session 2 | 0.7 | 0.7 | 2.0 | -0.6 | 0.8 | -0.8 | 0.8 | 0.9 | -0.8 | 0.5 | 0.8 | -1.4 | -1.4 | -0.8 | 0.8 | -0.9 | 0.7 | 0.5 | -0.8 | 0.7 | -0.3 | -1.3 | 0.6 | -1.2 | 0.1 | 0.1 | -0.0 | 0.1 | 0.2 | 0.7 | -0.2 | 0.9 | -0.9 | 1.1 | -0.9 | -0.8 | 0.8 | 0.0 | -0.5 | 0.8 | -0.5 | -1.2 | -1.0 | 0.7 | 0.4 | 0.7 | -0.7 | 0.2 | -0.8 | 0.7 | -0.8 | 0.8 | 0.9 | -1.3 | 1.2 | 1.4 | -0.7 | -0.8 | -1.3 |
Bone: tissue strength | 0.7 | 0.7 | 2.7 | -0.2 | 0.3 | -0.3 | 0.3 | 0.6 | -0.3 | -1.5 | 0.3 | 1.3 | 0.3 | -0.6 | 0.7 | -0.5 | 0.3 | 1.0 | 0.5 | 0.3 | 1.3 | 0.5 | 0.8 | 1.4 | -1.2 | 0.9 | -1.1 | 1.0 | -1.6 | 0.2 | -0.8 | -1.4 | 1.0 | -0.4 | 1.0 | -0.6 | 0.3 | 1.5 | -0.8 | 0.3 | -0.8 | 1.3 | -0.2 | 0.3 | 0.6 | 0.7 | -0.3 | -1.4 | -0.6 | 0.3 | -0.1 | 0.8 | 0.6 | 1.4 | 0.1 | -0.6 | -0.3 | -0.6 | 0.0 |
Time to tail flick, test, before self-admin | 0.7 | 0.7 | 1.8 | 0.8 | -0.8 | 0.8 | -0.8 | -0.6 | 0.8 | -0.6 | -0.8 | 1.3 | 1.3 | 0.7 | -0.8 | 0.7 | -0.7 | -0.2 | 1.1 | -0.7 | 0.3 | 1.2 | -0.7 | 1.3 | 0.1 | -0.2 | 0.0 | -0.1 | -0.4 | -0.7 | 0.4 | -0.5 | 1.2 | -1.2 | 1.2 | 0.5 | -0.8 | 0.3 | 0.8 | -0.8 | 0.9 | 1.3 | 0.9 | -0.7 | -0.4 | -0.4 | 0.8 | -0.3 | 0.7 | -0.8 | 0.8 | -1.1 | -0.6 | 1.3 | -1.2 | -1.2 | 0.8 | 0.5 | 1.1 |
Total resting periods, locomotor time 1 | 0.7 | 0.7 | 4.2 | 0.2 | -0.4 | 0.4 | -0.4 | -1.4 | 0.4 | 0.1 | -0.4 | 0.5 | 2.1 | 1.0 | -0.1 | 1.3 | -0.3 | -1.3 | -0.3 | -0.3 | 0.3 | 1.2 | -0.4 | 0.9 | -0.9 | 0.7 | -0.5 | 0.8 | -0.5 | -0.2 | -0.5 | -1.5 | -0.1 | -1.5 | -0.2 | 1.6 | -0.4 | -1.7 | 0.1 | -0.4 | 0.2 | 0.7 | 0.7 | -0.3 | 0.2 | -1.3 | 0.2 | -0.2 | 0.2 | -0.4 | 0.2 | -0.1 | -1.4 | 0.9 | -1.1 | -1.8 | 0.4 | 1.6 | 1.2 |
Zn content in liver | 0.7 | 0.8 | 3.5 | -0.6 | 0.7 | -0.7 | 0.7 | 0.8 | -0.7 | -1.9 | 0.7 | 1.0 | 0.5 | -0.7 | 0.4 | -0.7 | 0.6 | 1.1 | 0.1 | 0.6 | 1.7 | 0.4 | 0.3 | 1.1 | -1.4 | 1.2 | -1.4 | 1.3 | -1.5 | 0.6 | -1.1 | -1.5 | 0.7 | -0.2 | 0.7 | -0.9 | 0.6 | 1.1 | -0.4 | 0.6 | -0.4 | 1.1 | -0.4 | 0.6 | 1.0 | 0.9 | -0.6 | -1.6 | -0.5 | 0.7 | -0.4 | 0.4 | 0.8 | 1.0 | -0.2 | -0.4 | -0.7 | -0.9 | 0.2 |
Right kidney weight | 0.6 | 1.8 | 8.5 | 0.9 | -0.7 | 0.7 | -0.7 | 0.3 | 0.7 | -2.5 | -0.7 | 2.9 | 1.3 | 0.2 | -0.8 | 0.0 | -0.7 | 1.2 | 2.1 | -0.7 | 1.6 | 1.8 | -0.9 | 2.7 | -0.5 | 0.0 | -0.6 | 0.2 | -1.3 | -0.8 | 0.1 | -1.2 | 2.8 | -1.7 | 2.7 | -0.6 | -0.6 | 2.2 | 0.8 | -0.6 | 0.8 | 2.6 | 1.0 | -0.7 | -0.1 | 0.6 | 0.8 | -1.7 | 1.0 | -0.5 | 1.1 | -0.8 | 0.3 | 2.6 | -1.3 | -1.3 | 0.5 | -0.6 | 1.6 |
Tibia length | 0.6 | 1.6 | 9.1 | -0.2 | 0.3 | -0.3 | 0.3 | 1.1 | -0.3 | -2.5 | 0.3 | 2.1 | 0.1 | -1.0 | 0.8 | -0.9 | 0.3 | 1.7 | 1.2 | 0.3 | 2.0 | 0.8 | 0.8 | 2.2 | -1.6 | 1.3 | -1.7 | 1.5 | -3.0 | 0.2 | -1.2 | -1.7 | 1.8 | -0.9 | 1.8 | -1.2 | 0.3 | 2.8 | -0.9 | 0.3 | -0.9 | 2.1 | -0.2 | 0.3 | 0.8 | 1.2 | -0.3 | -2.1 | -1.2 | 0.3 | -0.0 | 0.8 | 1.1 | 2.2 | 0.0 | -0.8 | -0.3 | -1.2 | -0.3 |
Indifference point AUC | 0.6 | 0.7 | 3.1 | 0.7 | -0.6 | 0.6 | -0.6 | -1.2 | 0.6 | 0.8 | -0.6 | 0.0 | 1.5 | 1.3 | -0.9 | 1.3 | -0.5 | -1.4 | -0.3 | -0.5 | -0.9 | 0.8 | -1.0 | -0.1 | 0.3 | -0.4 | 0.5 | -0.3 | 1.4 | -0.7 | 0.5 | -0.1 | -0.4 | -0.7 | -0.4 | 1.3 | -0.5 | -1.8 | 1.2 | -0.5 | 1.2 | 0.0 | 0.8 | -0.5 | -0.4 | -1.2 | 0.7 | 0.6 | 1.1 | -0.7 | 0.5 | -1.0 | -1.2 | 0.1 | -1.1 | -1.0 | 0.7 | 1.3 | 1.2 |
Delay discounting total patch changes 12 sec | 0.6 | 0.8 | 3.6 | -0.6 | 0.7 | -0.7 | 0.7 | 0.6 | -0.7 | -1.5 | 0.7 | 1.5 | 1.0 | -0.4 | 0.4 | -0.4 | 0.6 | 0.8 | -0.2 | 0.6 | 1.6 | 0.5 | 0.5 | 1.0 | -1.5 | 1.3 | -1.5 | 1.4 | -1.0 | 0.6 | -1.1 | -1.9 | 0.5 | -0.6 | 0.4 | -0.6 | 0.7 | 1.0 | -0.3 | 0.7 | -0.3 | 1.1 | -0.3 | 0.6 | 1.1 | 0.7 | -0.7 | -1.7 | -0.1 | 0.7 | -0.5 | 0.5 | 0.6 | 1.4 | -0.3 | -0.8 | -0.7 | -0.6 | 0.6 |
Condit. Reinf. inactive responses | 0.6 | 0.8 | 3.3 | -0.9 | 0.7 | -0.7 | 0.7 | -0.0 | -0.7 | 1.3 | 0.7 | -1.5 | -0.4 | -0.2 | 0.7 | -0.1 | 0.8 | -0.6 | -1.7 | 0.8 | -0.4 | -1.1 | 0.6 | -1.6 | -0.3 | 0.4 | -0.1 | 0.3 | 1.2 | 0.9 | -0.5 | 0.0 | -1.8 | 1.4 | -1.8 | 0.2 | 0.8 | -1.4 | -0.5 | 0.8 | -0.6 | -1.7 | -0.7 | 0.8 | 0.6 | -0.1 | -0.9 | 0.6 | -0.3 | 0.9 | -1.0 | 0.6 | -0.0 | -1.4 | 0.8 | 0.9 | -0.9 | 0.2 | -0.5 |
Short access day 10 total infusions | 0.6 | 0.7 | 3.8 | -0.4 | 0.7 | -0.7 | 0.7 | 0.3 | -0.7 | -1.5 | 0.7 | 1.1 | 1.1 | -0.2 | 0.3 | -0.1 | 0.5 | 0.4 | -0.4 | 0.5 | 1.5 | 0.7 | 0.0 | 1.1 | -1.4 | 1.4 | -1.4 | 1.5 | -1.1 | 0.4 | -1.1 | -1.9 | 0.2 | -0.8 | 0.1 | -0.1 | 0.5 | -0.1 | 0.1 | 0.5 | 0.1 | 1.1 | -0.2 | 0.5 | 1.1 | 0.1 | -0.4 | -1.6 | 0.1 | 0.5 | -0.4 | 0.2 | 0.3 | 1.1 | -0.4 | -0.8 | -0.5 | -0.1 | 0.7 |
One hour access (0.3 mA shock) | 0.6 | 0.7 | 2.2 | -0.7 | 0.7 | -0.7 | 0.7 | 0.8 | -0.7 | -1.3 | 0.7 | 0.6 | 0.2 | -0.8 | 0.8 | -0.7 | 0.8 | 1.0 | -0.2 | 0.8 | 1.5 | 0.0 | 0.8 | 0.7 | -1.4 | 1.3 | -1.4 | 1.3 | -1.3 | 0.7 | -1.2 | -1.2 | 0.3 | -0.1 | 0.3 | -0.8 | 0.8 | 0.9 | -0.7 | 0.8 | -0.7 | 0.7 | -0.6 | 0.8 | 1.1 | 0.9 | -0.7 | -1.5 | -0.6 | 0.7 | -0.6 | 0.8 | 0.8 | 0.7 | 0.4 | -0.1 | -0.7 | -0.8 | -0.1 |
Locomotion distance, session 2 | 0.6 | 0.9 | 4.6 | 0.3 | -0.2 | 0.2 | -0.2 | -0.1 | 0.2 | 1.7 | -0.2 | -1.7 | -1.3 | 0.2 | -0.3 | 0.1 | -0.3 | -0.6 | -0.3 | -0.3 | -1.7 | -1.0 | -0.2 | -1.6 | 1.6 | -1.3 | 1.5 | -1.4 | 2.0 | -0.4 | 1.1 | 2.1 | -0.9 | 0.9 | -0.8 | 0.1 | -0.2 | -1.0 | 0.3 | -0.2 | 0.3 | -1.6 | -0.0 | -0.3 | -0.9 | -0.3 | 0.3 | 1.6 | 0.6 | -0.3 | 0.2 | -0.1 | -0.1 | -1.7 | 0.8 | 1.3 | 0.3 | 0.1 | -0.5 |
Locomotion velocity, hab. session 1 | 0.6 | 0.9 | 5.1 | 0.4 | -0.4 | 0.4 | -0.4 | 0.3 | 0.4 | 1.5 | -0.4 | -1.2 | -1.5 | -0.1 | -0.5 | -0.3 | -0.4 | 0.1 | 0.3 | -0.4 | -1.4 | -1.0 | -0.5 | -1.2 | 2.1 | -1.8 | 1.7 | -1.9 | 1.8 | -0.4 | 1.4 | 2.3 | -0.2 | 0.9 | -0.1 | -0.4 | -0.4 | 0.1 | 0.7 | -0.4 | 0.7 | -1.0 | 0.0 | -0.4 | -1.0 | 0.1 | 0.3 | 1.4 | 0.7 | -0.4 | 0.4 | -0.3 | 0.3 | -1.3 | 0.6 | 1.4 | 0.4 | -0.4 | -0.5 |
Bone: cortical thickness | 0.6 | 1.0 | 3.2 | -0.8 | 0.8 | -0.8 | 0.8 | 0.9 | -0.8 | 0.8 | 0.8 | -1.8 | -1.8 | -0.8 | 0.9 | -1.0 | 0.8 | 0.5 | -1.0 | 0.8 | -0.5 | -1.6 | 1.0 | -1.5 | 0.3 | -0.0 | 0.1 | -0.1 | 0.4 | 0.8 | -0.2 | 1.0 | -1.2 | 1.6 | -1.2 | -1.0 | 0.8 | 0.0 | -0.9 | 0.8 | -0.9 | -1.4 | -1.1 | 0.8 | 0.4 | 0.8 | -0.7 | 0.4 | -0.9 | 0.8 | -0.9 | 0.9 | 0.9 | -1.6 | 1.4 | 1.8 | -0.8 | -1.0 | -1.6 |
Active lever presses in extinction session 6 | 0.6 | 0.6 | 1.3 | -0.7 | 0.8 | -0.8 | 0.8 | 1.1 | -0.8 | -0.7 | 0.8 | -0.1 | -0.6 | -0.8 | 0.9 | -1.0 | 0.8 | 1.1 | -0.3 | 0.8 | 0.7 | -0.7 | 0.6 | -0.1 | -0.8 | 0.7 | -0.9 | 0.7 | -0.7 | 0.7 | -0.7 | -0.3 | -0.1 | 0.6 | -0.1 | -1.1 | 1.0 | 1.0 | -0.6 | 1.0 | -0.6 | -0.2 | -0.8 | 0.8 | 0.8 | 1.1 | -0.7 | -0.8 | -0.7 | 0.8 | -0.7 | 0.8 | 1.1 | -0.2 | 0.7 | 0.7 | -0.8 | -1.1 | -0.7 |
Delta distance traveled before/after self-admin | 0.6 | 0.7 | 3.7 | -0.5 | 0.4 | -0.4 | 0.4 | 0.1 | -0.4 | -1.3 | 0.4 | 1.1 | 0.8 | -0.3 | 0.8 | -0.0 | 0.5 | 0.2 | -0.4 | 0.5 | 1.3 | 0.5 | 0.9 | 1.0 | -1.5 | 1.4 | -1.4 | 1.5 | -1.7 | 0.5 | -1.3 | -1.9 | 0.1 | -0.8 | -0.0 | 0.2 | 0.5 | 0.1 | -0.9 | 0.5 | -0.9 | 1.0 | -0.3 | 0.5 | 1.0 | 0.0 | -0.5 | -1.3 | -0.8 | 0.4 | -0.5 | 0.8 | 0.1 | 1.1 | -0.0 | -1.0 | -0.4 | 0.2 | 0.1 |
Ambulatory time before self-admin | 0.6 | 0.6 | 1.5 | 0.7 | -0.8 | 0.8 | -0.8 | -0.3 | 0.8 | 0.6 | -0.8 | 0.2 | 0.4 | 0.5 | -0.9 | 0.4 | -0.7 | -0.2 | 1.0 | -0.7 | -0.6 | 0.4 | -1.2 | 0.3 | 1.1 | -1.1 | 0.9 | -1.1 | 1.2 | -0.6 | 1.2 | 0.9 | 0.8 | -0.1 | 0.9 | 0.2 | -0.8 | 0.1 | 1.2 | -0.8 | 1.2 | 0.2 | 0.8 | -0.7 | -0.9 | -0.2 | 0.7 | 0.5 | 1.2 | -0.8 | 0.8 | -0.9 | -0.3 | 0.3 | -0.7 | -0.2 | 0.8 | 0.2 | 0.8 |
Total heroin consumption | 0.6 | 0.7 | 4.5 | 0.4 | -0.2 | 0.2 | -0.2 | -0.9 | 0.2 | 1.4 | -0.2 | -1.1 | 0.1 | 0.8 | -0.1 | 0.9 | -0.4 | -1.5 | -0.9 | -0.4 | -1.5 | -0.3 | -0.3 | -1.2 | 0.9 | -0.6 | 1.0 | -0.7 | 1.3 | -0.4 | 0.5 | 0.6 | -1.4 | 0.3 | -1.4 | 1.2 | -0.1 | -2.1 | 0.3 | -0.1 | 0.3 | -1.2 | 0.2 | -0.4 | -0.6 | -1.2 | 0.4 | 1.5 | 0.3 | -0.3 | 0.1 | -0.1 | -0.9 | -1.2 | 0.1 | 0.2 | 0.3 | 1.2 | -0.0 |
Rest time, locomotor task time 1 | 0.6 | 0.6 | 5.4 | -0.2 | 0.2 | -0.2 | 0.2 | -1.1 | -0.2 | 0.6 | 0.2 | -0.5 | 1.5 | 0.7 | 0.5 | 1.0 | 0.2 | -1.5 | -1.3 | 0.2 | -0.2 | 0.4 | 0.4 | -0.1 | -1.1 | 1.1 | -0.7 | 1.0 | -0.1 | 0.3 | -0.9 | -1.3 | -1.2 | -0.7 | -1.3 | 1.4 | 0.2 | -2.3 | -0.4 | 0.2 | -0.5 | -0.4 | 0.0 | 0.2 | 0.6 | -1.2 | -0.2 | 0.1 | -0.2 | 0.2 | -0.4 | 0.5 | -1.1 | -0.2 | -0.2 | -1.0 | -0.2 | 1.4 | 0.5 |
Distance moved, locomotor task time 1 | 0.6 | 0.7 | 6.5 | 0.1 | -0.4 | 0.4 | -0.4 | 1.0 | 0.4 | -1.1 | -0.4 | 1.3 | -0.6 | -0.7 | -0.4 | -0.7 | -0.3 | 1.5 | 1.6 | -0.3 | 0.8 | 0.2 | -0.5 | 1.0 | 0.6 | -0.7 | 0.2 | -0.6 | -0.2 | -0.2 | 0.7 | 0.5 | 1.8 | 0.0 | 1.8 | -1.1 | -0.4 | 2.5 | 0.6 | -0.4 | 0.6 | 1.1 | 0.3 | -0.3 | -0.4 | 1.1 | 0.2 | -0.7 | 0.5 | -0.4 | 0.5 | -0.4 | 1.0 | 1.2 | -0.3 | 0.2 | 0.4 | -1.1 | 0.1 |
Run reversals in cocaine runway, males | 0.6 | 0.6 | 2.7 | 0.2 | -0.4 | 0.4 | -0.4 | -0.7 | 0.4 | 1.6 | -0.4 | -1.2 | -0.8 | 0.4 | -0.3 | 0.5 | -0.4 | -1.1 | -0.4 | -0.4 | -1.6 | -0.6 | 0.2 | -1.2 | 1.1 | -0.9 | 1.2 | -1.0 | 1.1 | -0.2 | 0.7 | 1.3 | -1.0 | 0.6 | -0.9 | 0.8 | -0.4 | -1.0 | -0.2 | -0.4 | -0.2 | -1.2 | 0.1 | -0.4 | -0.8 | -0.8 | 0.2 | 1.5 | -0.2 | -0.4 | 0.2 | -0.1 | -0.7 | -1.1 | 0.4 | 0.6 | 0.4 | 0.8 | -0.7 |
Soleus weight | 0.5 | 1.4 | 2.7 | 1.4 | -1.4 | 1.4 | -1.4 | -0.7 | 1.4 | 0.1 | -1.4 | 0.8 | 0.2 | 0.9 | -1.3 | 0.9 | -1.4 | -0.5 | 1.6 | -1.4 | -0.9 | 0.9 | -1.3 | 0.7 | 1.5 | -1.6 | 1.5 | -1.6 | 0.9 | -1.4 | 1.6 | 1.4 | 1.2 | -1.2 | 1.3 | 0.6 | -1.4 | 0.3 | 1.2 | -1.4 | 1.3 | 0.6 | 1.3 | -1.4 | -1.6 | -0.8 | 1.5 | 1.0 | 1.4 | -1.4 | 1.5 | -1.3 | -0.7 | 0.7 | -0.9 | -0.4 | 1.4 | 0.6 | 0.9 |
Delay discounting total patch changes 18 sec | 0.5 | 0.7 | 1.8 | 0.9 | -0.6 | 0.6 | -0.6 | -0.8 | 0.6 | 0.1 | -0.6 | 0.7 | 1.3 | 1.1 | -1.0 | 1.1 | -0.7 | -0.9 | 0.4 | -0.7 | -0.4 | 1.0 | -1.1 | 0.5 | 0.4 | -0.5 | 0.5 | -0.5 | 0.9 | -0.9 | 0.7 | -0.1 | 0.4 | -1.0 | 0.4 | 0.9 | -0.7 | -0.9 | 1.1 | -0.7 | 1.2 | 0.5 | 1.0 | -0.7 | -0.6 | -0.9 | 0.9 | 0.2 | 1.3 | -0.8 | 0.8 | -1.0 | -0.8 | 0.5 | -1.1 | -1.0 | 0.8 | 0.9 | 1.3 |
Delay discounting time to switch 0 sec | 0.5 | 0.7 | 4.1 | -0.0 | -0.1 | 0.1 | -0.1 | 0.5 | 0.1 | 1.2 | -0.1 | -1.4 | -2.0 | -0.6 | 0.4 | -0.7 | -0.1 | 0.4 | 0.1 | -0.1 | -1.1 | -1.3 | 0.2 | -1.2 | 1.5 | -1.2 | 1.3 | -1.3 | 0.8 | -0.0 | 0.9 | 1.9 | -0.4 | 1.4 | -0.3 | -0.7 | -0.1 | 0.5 | -0.2 | -0.1 | -0.2 | -1.3 | -0.4 | -0.1 | -0.8 | 0.4 | -0.0 | 1.3 | -0.3 | -0.0 | 0.0 | 0.2 | 0.5 | -1.3 | 1.0 | 1.7 | 0.0 | -0.7 | -1.3 |
Conditioned locomotion | 0.5 | 0.6 | 1.2 | 0.9 | -0.8 | 0.8 | -0.8 | -0.9 | 0.8 | 1.0 | -0.8 | 0.1 | 0.5 | 1.1 | -1.0 | 0.9 | -0.8 | -1.0 | 0.4 | -0.8 | -1.0 | 0.5 | -1.1 | -0.0 | 0.8 | -0.8 | 0.8 | -0.8 | 0.8 | -0.9 | 0.9 | 0.5 | 0.1 | -0.4 | 0.1 | 0.9 | -0.8 | -0.7 | 1.0 | -0.8 | 1.0 | -0.1 | 0.8 | -0.8 | -0.9 | -0.9 | 0.9 | 0.9 | 0.7 | -0.8 | 0.8 | -1.1 | -0.9 | 0.0 | -0.8 | -0.4 | 0.8 | 0.9 | 0.5 |
Pavlov. Cond. index score | 0.5 | 0.6 | 1.4 | -0.8 | 0.8 | -0.8 | 0.8 | 1.2 | -0.8 | -0.6 | 0.8 | -0.4 | -1.1 | -1.0 | 0.6 | -1.1 | 0.8 | 1.1 | -0.4 | 0.8 | 0.6 | -0.9 | 0.6 | -0.3 | -0.4 | 0.5 | -0.5 | 0.5 | -0.4 | 0.8 | -0.6 | 0.1 | -0.2 | 0.9 | -0.2 | -1.2 | 0.8 | 0.9 | -0.5 | 0.8 | -0.7 | -0.3 | -0.9 | 0.8 | 0.7 | 1.1 | -0.7 | -0.5 | -0.7 | 0.8 | -0.7 | 0.7 | 1.2 | -0.3 | 0.9 | 1.1 | -0.8 | -1.2 | -0.9 |
Intermittent access day 1 total infusions | 0.5 | 0.5 | 1.1 | -0.8 | 1.0 | -1.0 | 1.0 | 0.8 | -1.0 | -0.5 | 1.0 | -0.2 | -0.3 | -0.7 | 0.7 | -0.8 | 0.8 | 0.8 | -0.6 | 0.8 | 0.8 | -0.5 | 0.4 | -0.2 | -0.8 | 0.8 | -0.9 | 0.8 | -0.3 | 0.8 | -0.8 | -0.5 | -0.3 | 0.7 | -0.3 | -1.0 | 0.8 | 0.5 | -0.3 | 0.8 | -0.3 | -0.2 | -0.8 | 0.8 | 1.0 | 0.9 | -0.8 | -0.8 | -0.3 | 0.9 | -0.8 | 0.4 | 0.8 | -0.2 | 0.4 | 0.6 | -0.9 | -1.0 | -0.3 |
Progressive ratio test 2 inactive lever presses | 0.5 | 0.6 | 1.9 | 0.6 | -0.6 | 0.6 | -0.6 | -0.4 | 0.6 | -1.2 | -0.6 | 1.3 | 1.0 | 0.5 | -0.6 | 0.4 | -0.6 | 0.1 | 1.2 | -0.6 | 0.6 | 1.1 | -0.3 | 1.4 | -0.4 | 0.1 | -0.3 | 0.1 | -0.8 | -0.6 | 0.0 | -0.5 | 1.4 | -1.3 | 1.4 | 0.2 | -0.5 | 0.9 | 0.4 | -0.5 | 0.4 | 1.4 | 0.7 | -0.6 | -0.2 | -0.1 | 0.6 | -0.6 | 0.4 | -0.5 | 0.7 | -0.4 | -0.4 | 1.4 | -0.8 | -1.1 | 0.5 | 0.2 | 0.9 |
Total sessions with >9 infusions | 0.5 | 0.5 | 2.1 | 0.2 | 0.1 | -0.1 | 0.1 | -0.3 | -0.1 | -1.4 | 0.1 | 1.3 | 1.5 | 0.3 | -0.3 | 0.5 | -0.1 | -0.1 | 0.2 | -0.1 | 1.0 | 1.1 | -0.3 | 1.4 | -0.9 | 0.8 | -0.8 | 0.9 | -0.7 | -0.2 | -0.5 | -1.5 | 0.6 | -1.3 | 0.6 | 0.3 | -0.2 | -0.2 | 0.5 | -0.2 | 0.5 | 1.4 | 0.4 | -0.1 | 0.5 | -0.3 | 0.2 | -1.0 | 0.6 | -0.1 | 0.2 | -0.2 | -0.3 | 1.4 | -0.8 | -1.2 | 0.1 | 0.3 | 1.2 |
Short access total infusions | 0.5 | 0.6 | 3.0 | -0.1 | 0.3 | -0.3 | 0.3 | -0.0 | -0.3 | -1.5 | 0.3 | 1.3 | 1.3 | 0.1 | -0.0 | 0.2 | 0.1 | 0.2 | 0.0 | 0.1 | 1.3 | 1.0 | -0.2 | 1.4 | -1.2 | 1.1 | -1.2 | 1.2 | -1.0 | 0.0 | -0.8 | -1.7 | 0.6 | -1.1 | 0.5 | 0.0 | 0.1 | 0.0 | 0.2 | 0.1 | 0.2 | 1.4 | 0.1 | 0.1 | 0.8 | -0.0 | -0.1 | -1.4 | 0.3 | 0.2 | -0.0 | -0.1 | -0.0 | 1.4 | -0.8 | -1.0 | -0.2 | 0.0 | 0.9 |
Locomotion distance, session 1 | 0.5 | 0.7 | 4.0 | 0.5 | -0.3 | 0.3 | -0.3 | 0.3 | 0.3 | 1.4 | -0.3 | -1.2 | -1.3 | 0.1 | -0.6 | -0.2 | -0.3 | -0.1 | 0.2 | -0.3 | -1.4 | -0.9 | -0.7 | -1.1 | 1.7 | -1.4 | 1.4 | -1.5 | 1.6 | -0.4 | 1.2 | 2.0 | -0.3 | 1.1 | -0.2 | -0.3 | -0.3 | -0.2 | 0.6 | -0.3 | 0.7 | -1.1 | 0.0 | -0.3 | -0.9 | 0.1 | 0.4 | 1.2 | 0.6 | -0.3 | 0.4 | -0.4 | 0.3 | -1.2 | 0.4 | 1.3 | 0.3 | -0.3 | -0.5 |
Locomotion velocity, session 3 | 0.5 | 0.6 | 2.4 | 0.6 | -0.6 | 0.6 | -0.6 | -0.9 | 0.6 | 1.4 | -0.6 | -0.8 | 0.3 | 0.9 | -0.5 | 0.9 | -0.6 | -1.2 | -0.2 | -0.6 | -1.2 | 0.0 | -0.6 | -0.7 | 1.0 | -0.9 | 1.0 | -0.9 | 1.5 | -0.5 | 0.8 | 0.6 | -0.6 | 0.3 | -0.6 | 1.1 | -0.6 | -1.5 | 0.5 | -0.6 | 0.6 | -0.7 | 0.5 | -0.6 | -0.8 | -1.1 | 0.7 | 1.2 | 0.8 | -0.6 | 0.4 | -0.5 | -0.9 | -0.7 | -0.3 | -0.1 | 0.6 | 1.1 | 0.4 |
Stereotopy head waving duration, day 3 | 0.5 | 0.6 | 1.2 | 0.9 | -0.9 | 0.9 | -0.9 | -0.7 | 0.9 | 0.4 | -0.9 | 0.1 | 0.3 | 0.8 | -0.8 | 0.8 | -1.0 | -0.7 | 0.7 | -1.0 | -0.9 | 0.5 | -0.6 | 0.1 | 1.1 | -1.1 | 1.1 | -1.1 | 0.5 | -0.9 | 0.9 | 0.8 | 0.4 | -0.7 | 0.4 | 0.8 | -0.9 | -0.4 | 0.6 | -0.9 | 0.6 | 0.1 | 0.8 | -1.0 | -1.1 | -0.8 | 0.9 | 0.9 | 0.7 | -1.0 | 0.8 | -0.7 | -0.7 | 0.2 | -0.5 | -0.4 | 1.0 | 0.8 | 0.5 |
Condit. Reinf. lever presses | 0.5 | 0.7 | 3.3 | 0.3 | -0.4 | 0.4 | -0.4 | -0.1 | 0.4 | 1.6 | -0.4 | -1.4 | -1.2 | 0.0 | -0.3 | -0.0 | -0.4 | -0.3 | -0.1 | -0.4 | -1.2 | -0.9 | -0.4 | -1.2 | 1.6 | -1.4 | 1.4 | -1.5 | 1.7 | -0.2 | 1.2 | 1.8 | -0.6 | 1.1 | -0.5 | 0.1 | -0.3 | -0.6 | 0.6 | -0.3 | 0.6 | -1.2 | 0.0 | -0.4 | -1.0 | -0.3 | 0.4 | 1.5 | 0.5 | -0.4 | 0.2 | -0.3 | -0.1 | -1.4 | 0.5 | 1.1 | 0.4 | 0.1 | -0.5 |
Total locomotion distance, hab. session 1 | 0.5 | 0.7 | 4.0 | 0.3 | -0.2 | 0.2 | -0.2 | 0.2 | 0.2 | 1.5 | -0.2 | -1.3 | -1.2 | 0.0 | -0.5 | -0.2 | -0.2 | -0.1 | -0.0 | -0.2 | -1.5 | -1.0 | -0.3 | -1.3 | 1.8 | -1.5 | 1.5 | -1.6 | 1.9 | -0.3 | 1.2 | 2.0 | -0.5 | 0.9 | -0.4 | -0.3 | -0.2 | -0.3 | 0.6 | -0.2 | 0.6 | -1.1 | -0.0 | -0.2 | -0.8 | 0.0 | 0.3 | 1.3 | 0.7 | -0.2 | 0.2 | -0.3 | 0.2 | -1.4 | 0.6 | 1.3 | 0.2 | -0.3 | -0.4 |
Time in familiar zone, hab. session 2 | 0.5 | 0.5 | 2.2 | 0.3 | -0.5 | 0.5 | -0.5 | -0.7 | 0.5 | -1.0 | -0.5 | 1.5 | 1.4 | 0.6 | -0.4 | 0.7 | -0.4 | -0.3 | 0.6 | -0.4 | 0.7 | 1.3 | -0.3 | 1.3 | -0.6 | 0.4 | -0.5 | 0.4 | -0.8 | -0.4 | -0.2 | -1.2 | 0.9 | -1.2 | 0.8 | 0.6 | -0.4 | 0.2 | 0.1 | -0.4 | 0.1 | 1.3 | 0.7 | -0.4 | 0.1 | -0.5 | 0.4 | -0.7 | 0.4 | -0.4 | 0.5 | -0.4 | -0.7 | 1.4 | -1.0 | -1.4 | 0.4 | 0.6 | 1.1 |
Novelty place preference | 0.5 | 0.5 | 2.8 | 0.2 | -0.0 | 0.0 | -0.0 | 0.7 | 0.0 | -1.7 | -0.0 | 1.2 | 0.2 | -0.4 | -0.4 | -0.4 | -0.1 | 1.1 | 1.1 | -0.1 | 1.1 | 0.6 | -0.2 | 1.4 | -0.4 | 0.2 | -0.5 | 0.3 | -1.0 | -0.1 | -0.1 | -0.5 | 1.4 | -0.4 | 1.4 | -0.8 | -0.0 | 1.4 | 0.2 | -0.0 | 0.2 | 1.4 | 0.2 | -0.1 | 0.1 | 0.7 | 0.2 | -1.1 | 0.1 | -0.1 | 0.3 | -0.3 | 0.7 | 1.1 | -0.5 | -0.4 | 0.1 | -0.8 | 0.4 |
Pavlov. Cond. response bias | 0.5 | 0.6 | 2.5 | -0.7 | 0.6 | -0.6 | 0.6 | 0.7 | -0.6 | 0.7 | 0.6 | -1.0 | -1.2 | -0.8 | 0.9 | -0.8 | 0.6 | 0.5 | -0.7 | 0.6 | -0.1 | -1.2 | 0.7 | -1.1 | 0.3 | -0.1 | 0.2 | -0.1 | 0.4 | 0.7 | -0.2 | 0.5 | -0.9 | 1.6 | -0.8 | -0.7 | 0.7 | 0.2 | -0.5 | 0.7 | -0.5 | -1.1 | -0.8 | 0.6 | 0.3 | 0.7 | -0.6 | 0.3 | -0.5 | 0.6 | -0.7 | 0.7 | 0.7 | -1.1 | 1.1 | 1.3 | -0.6 | -0.7 | -1.0 |
Bone: cortical thickness | 0.5 | 0.5 | 2.4 | 0.4 | -0.3 | 0.3 | -0.3 | -0.5 | 0.3 | 1.3 | -0.3 | -1.3 | -0.4 | 0.6 | -0.5 | 0.4 | -0.4 | -0.8 | -0.3 | -0.4 | -1.3 | -0.4 | -0.5 | -1.0 | 1.1 | -1.0 | 1.1 | -1.0 | 1.6 | -0.4 | 0.8 | 1.2 | -0.7 | 0.4 | -0.7 | 0.5 | -0.4 | -1.3 | 0.5 | -0.4 | 0.5 | -1.0 | 0.2 | -0.4 | -0.7 | -0.6 | 0.5 | 1.2 | 0.6 | -0.3 | 0.3 | -0.5 | -0.5 | -1.3 | 0.0 | 0.6 | 0.3 | 0.5 | -0.0 |
Bone: elastic work | 0.5 | 0.7 | 3.9 | -0.5 | 0.5 | -0.5 | 0.5 | 1.2 | -0.5 | 0.3 | 0.5 | -0.8 | -2.0 | -1.1 | 0.6 | -1.3 | 0.5 | 1.2 | -0.0 | 0.5 | -0.0 | -1.3 | 0.7 | -0.6 | 0.4 | -0.2 | 0.2 | -0.2 | -0.3 | 0.5 | -0.0 | 0.9 | -0.1 | 1.4 | -0.1 | -1.3 | 0.5 | 1.3 | -0.7 | 0.5 | -0.7 | -0.6 | -0.9 | 0.5 | 0.1 | 1.1 | -0.5 | -0.0 | -0.9 | 0.5 | -0.5 | 0.6 | 1.2 | -0.7 | 1.2 | 1.6 | -0.5 | -1.3 | -1.5 |
Bone: stiffness | 0.5 | 0.8 | 2.0 | -0.9 | 1.0 | -1.0 | 1.0 | 0.5 | -1.0 | 0.6 | 1.0 | -1.4 | -0.5 | -0.5 | 0.9 | -0.6 | 1.0 | 0.1 | -1.4 | 1.0 | -0.1 | -1.0 | 0.9 | -1.1 | -0.5 | 0.7 | -0.5 | 0.6 | 0.6 | 0.9 | -0.7 | -0.3 | -1.4 | 1.4 | -1.4 | -0.4 | 1.0 | -0.9 | -0.8 | 1.0 | -0.8 | -1.2 | -0.9 | 1.0 | 0.9 | 0.5 | -1.0 | -0.1 | -0.4 | 1.0 | -1.1 | 0.8 | 0.5 | -1.2 | 0.9 | 0.9 | -1.0 | -0.4 | -0.6 |
Delta time to tail flick, vehicle, before/after SA | 0.5 | 0.5 | 1.5 | 0.6 | -0.7 | 0.7 | -0.7 | -0.8 | 0.7 | -0.5 | -0.7 | 0.9 | 1.1 | 0.6 | -0.7 | 0.7 | -0.6 | -0.5 | 0.7 | -0.6 | 0.3 | 1.1 | -0.5 | 1.0 | -0.1 | -0.1 | 0.0 | -0.0 | -0.3 | -0.5 | 0.2 | -0.5 | 0.8 | -1.2 | 0.7 | 0.7 | -0.7 | -0.2 | 0.4 | -0.7 | 0.4 | 0.9 | 0.8 | -0.6 | -0.4 | -0.7 | 0.6 | -0.2 | 0.5 | -0.6 | 0.6 | -0.5 | -0.8 | 1.0 | -0.8 | -1.1 | 0.6 | 0.7 | 0.9 |
Ambulatory time after self-admin | 0.5 | 0.5 | 2.6 | 0.3 | -0.5 | 0.5 | -0.5 | -0.0 | 0.5 | -0.9 | -0.5 | 1.3 | 1.1 | 0.1 | -0.0 | 0.2 | -0.2 | 0.5 | 1.1 | -0.2 | 0.9 | 1.1 | -0.5 | 1.6 | -0.3 | 0.2 | -0.4 | 0.3 | -0.7 | -0.2 | 0.1 | -0.9 | 1.4 | -0.9 | 1.4 | -0.0 | -0.4 | 0.9 | 0.4 | -0.4 | 0.4 | 1.5 | 0.6 | -0.2 | 0.1 | 0.2 | 0.3 | -1.0 | 0.5 | -0.5 | 0.4 | -0.3 | -0.0 | 1.6 | -0.8 | -1.1 | 0.5 | -0.0 | 0.9 |
Locomotion in novel chamber | 0.5 | 0.6 | 2.6 | -0.5 | 0.5 | -0.5 | 0.5 | 0.8 | -0.5 | 1.4 | 0.5 | -1.3 | -1.2 | -0.6 | 0.6 | -0.7 | 0.7 | 0.3 | -0.8 | 0.7 | -0.6 | -1.3 | 0.1 | -1.3 | 0.4 | -0.2 | 0.2 | -0.2 | 1.0 | 0.5 | 0.2 | 1.0 | -1.0 | 1.6 | -0.9 | -0.7 | 0.6 | -0.1 | -0.1 | 0.6 | -0.1 | -1.4 | -0.7 | 0.7 | 0.3 | 0.7 | -0.6 | 0.3 | -0.2 | 0.5 | -0.7 | 0.3 | 0.8 | -1.3 | 0.8 | 1.4 | -0.5 | -0.7 | -0.9 |
Locomotion in novel chamber post-restriction | 0.5 | 0.6 | 1.3 | 1.0 | -0.7 | 0.7 | -0.7 | -0.7 | 0.7 | -0.2 | -0.7 | 0.8 | 0.9 | 0.9 | -1.1 | 0.8 | -0.8 | -0.5 | 0.8 | -0.8 | -0.6 | 0.9 | -0.9 | 0.9 | 0.4 | -0.5 | 0.4 | -0.5 | 0.5 | -1.0 | 0.7 | -0.1 | 0.8 | -0.9 | 0.8 | 0.6 | -0.8 | -0.1 | 0.9 | -0.8 | 0.9 | 0.8 | 0.9 | -0.8 | -0.6 | -0.7 | 0.9 | 0.2 | 0.8 | -0.8 | 0.9 | -1.1 | -0.7 | 0.9 | -1.1 | -0.8 | 0.8 | 0.6 | 0.9 |
Length without tail | 0.4 | 0.9 | 3.2 | -0.9 | 0.9 | -0.9 | 0.9 | 0.3 | -0.9 | 1.4 | 0.9 | -1.6 | -1.0 | -0.5 | 0.8 | -0.5 | 0.8 | -0.2 | -1.5 | 0.8 | -0.6 | -1.4 | 0.7 | -1.7 | 0.1 | 0.3 | 0.1 | 0.2 | 0.9 | 0.9 | -0.4 | 0.4 | -1.7 | 1.5 | -1.7 | -0.3 | 0.8 | -0.8 | -0.6 | 0.8 | -0.6 | -1.8 | -1.0 | 0.8 | 0.5 | 0.2 | -0.9 | 0.6 | -0.7 | 0.9 | -1.0 | 0.9 | 0.3 | -1.6 | 1.2 | 1.3 | -0.9 | -0.3 | -1.1 |
Intraocular pressure | 0.4 | 0.5 | 3.5 | 0.1 | -0.2 | 0.2 | -0.2 | 0.1 | 0.2 | 1.4 | -0.2 | -1.1 | -0.7 | 0.1 | -0.4 | -0.0 | -0.2 | -0.1 | -0.1 | -0.2 | -1.0 | -0.7 | -0.9 | -1.0 | 1.4 | -1.2 | 1.2 | -1.3 | 1.9 | -0.1 | 1.0 | 1.5 | -0.4 | 1.0 | -0.4 | -0.1 | -0.2 | -0.5 | 0.8 | -0.2 | 0.8 | -1.0 | 0.0 | -0.2 | -0.6 | -0.0 | 0.2 | 1.1 | 1.1 | -0.2 | 0.2 | -0.6 | 0.1 | -1.1 | 0.1 | 1.0 | 0.2 | -0.1 | 0.0 |
Mean time between licks in bursts | 0.4 | 0.5 | 3.3 | 0.0 | -0.1 | 0.1 | -0.1 | 0.1 | 0.1 | 1.2 | -0.1 | -1.4 | -1.5 | -0.3 | 0.2 | -0.2 | -0.1 | -0.2 | -0.3 | -0.1 | -1.1 | -1.0 | 0.5 | -1.2 | 1.0 | -0.8 | 1.0 | -0.9 | 0.7 | 0.0 | 0.5 | 1.8 | -0.8 | 0.5 | -0.7 | -0.0 | -0.0 | -0.5 | -0.6 | -0.0 | -0.6 | -1.2 | -0.3 | -0.1 | -0.6 | -0.1 | 0.0 | 1.2 | -0.3 | -0.0 | -0.1 | 0.4 | 0.1 | -1.4 | 1.1 | 1.2 | 0.0 | -0.0 | -1.0 |
Locomotor testing rearing | 0.4 | 0.6 | 2.7 | -0.4 | 0.4 | -0.4 | 0.4 | 1.0 | -0.4 | -1.5 | 0.4 | 1.2 | 0.3 | -0.6 | 0.0 | -0.7 | 0.5 | 1.3 | 0.5 | 0.5 | 1.4 | 0.3 | 0.1 | 1.2 | -0.8 | 0.7 | -1.0 | 0.8 | -1.3 | 0.3 | -0.6 | -1.1 | 1.1 | -0.1 | 1.0 | -1.0 | 0.6 | 1.6 | -0.2 | 0.6 | -0.2 | 1.2 | -0.2 | 0.5 | 0.7 | 1.1 | -0.4 | -1.5 | -0.2 | 0.5 | -0.2 | 0.0 | 1.0 | 1.2 | -0.3 | -0.2 | -0.5 | -1.0 | 0.2 |
Pavlov. Cond. lever contacts | 0.4 | 0.6 | 1.7 | -0.7 | 0.8 | -0.8 | 0.8 | 1.1 | -0.8 | -1.3 | 0.8 | 0.6 | -0.3 | -0.8 | 0.4 | -0.9 | 0.7 | 1.2 | -0.0 | 0.7 | 1.2 | -0.2 | 0.4 | 0.6 | -0.9 | 0.8 | -1.0 | 0.9 | -0.9 | 0.7 | -0.7 | -0.8 | 0.4 | 0.5 | 0.4 | -1.1 | 0.8 | 1.2 | -0.3 | 0.8 | -0.5 | 0.5 | -0.6 | 0.7 | 0.9 | 1.1 | -0.6 | -1.2 | -0.4 | 0.8 | -0.5 | 0.4 | 1.1 | 0.6 | 0.2 | 0.3 | -0.8 | -1.1 | -0.3 |
Pavlov. Cond. lever-magazine prob. diff. | 0.4 | 0.6 | 1.2 | -0.8 | 0.8 | -0.8 | 0.8 | 1.1 | -0.8 | -0.6 | 0.8 | -0.4 | -1.0 | -1.0 | 0.7 | -1.0 | 0.8 | 1.0 | -0.4 | 0.8 | 0.6 | -0.8 | 0.7 | -0.3 | -0.4 | 0.5 | -0.5 | 0.5 | -0.4 | 0.8 | -0.6 | 0.0 | -0.2 | 0.9 | -0.2 | -1.1 | 0.8 | 0.8 | -0.5 | 0.8 | -0.7 | -0.3 | -0.8 | 0.8 | 0.7 | 1.0 | -0.7 | -0.5 | -0.6 | 0.8 | -0.7 | 0.7 | 1.1 | -0.3 | 0.9 | 1.0 | -0.8 | -1.1 | -0.8 |
Progressive ratio test 2 active lever presses | 0.4 | 0.5 | 1.9 | -0.3 | 0.3 | -0.3 | 0.3 | 0.5 | -0.3 | -1.4 | 0.3 | 0.8 | 0.2 | -0.5 | 0.4 | -0.5 | 0.4 | 0.9 | 0.3 | 0.4 | 1.2 | 0.3 | 0.7 | 0.9 | -1.2 | 1.0 | -1.2 | 1.1 | -1.3 | 0.3 | -0.8 | -1.0 | 0.7 | -0.4 | 0.7 | -0.6 | 0.4 | 1.1 | -0.6 | 0.4 | -0.6 | 0.9 | -0.3 | 0.4 | 0.8 | 0.7 | -0.3 | -1.3 | -0.6 | 0.4 | -0.3 | 0.4 | 0.5 | 0.9 | 0.0 | -0.4 | -0.4 | -0.6 | -0.1 |
Locomotion distance, session 3 | 0.4 | 0.4 | 3.1 | 0.0 | 0.1 | -0.1 | 0.1 | -0.0 | -0.1 | 1.4 | 0.1 | -1.2 | -0.5 | 0.1 | -0.2 | 0.0 | 0.1 | -0.5 | -0.6 | 0.1 | -1.0 | -0.8 | -0.3 | -1.2 | 1.0 | -0.7 | 0.9 | -0.8 | 1.8 | 0.1 | 0.6 | 0.9 | -0.9 | 1.1 | -0.9 | 0.1 | 0.2 | -0.9 | 0.3 | 0.2 | 0.4 | -1.2 | -0.2 | 0.1 | -0.2 | -0.2 | 0.0 | 0.9 | 0.6 | 0.1 | -0.1 | -0.3 | -0.0 | -1.2 | 0.3 | 0.9 | -0.1 | 0.1 | -0.1 |
Time in familiar zone, hab. session 1 | 0.4 | 0.4 | 1.1 | 0.8 | -0.5 | 0.5 | -0.5 | -0.6 | 0.5 | -0.3 | -0.5 | 0.9 | 1.1 | 0.8 | -0.6 | 0.8 | -0.5 | -0.5 | 0.6 | -0.5 | -0.1 | 1.0 | -0.7 | 0.8 | 0.1 | -0.2 | 0.1 | -0.1 | -0.0 | -0.7 | 0.2 | -0.5 | 0.6 | -0.9 | 0.6 | 0.6 | -0.5 | -0.2 | 0.5 | -0.5 | 0.6 | 0.8 | 0.7 | -0.5 | -0.3 | -0.6 | 0.7 | -0.1 | 0.7 | -0.5 | 0.7 | -0.7 | -0.6 | 0.9 | -0.9 | -1.0 | 0.5 | 0.6 | 1.0 |
Total locomotion distance, hab. session 2 | 0.4 | 0.5 | 1.9 | 0.7 | -0.6 | 0.6 | -0.6 | 0.3 | 0.6 | 0.1 | -0.6 | -0.1 | -0.5 | 0.2 | -1.0 | -0.0 | -0.5 | 0.3 | 0.9 | -0.5 | -0.6 | -0.0 | -0.8 | 0.1 | 1.4 | -1.3 | 1.1 | -1.3 | 1.1 | -0.7 | 1.2 | 1.3 | 0.7 | -0.0 | 0.8 | -0.3 | -0.5 | 0.5 | 1.0 | -0.5 | 1.0 | 0.1 | 0.5 | -0.5 | -0.8 | 0.2 | 0.8 | 0.5 | 1.0 | -0.5 | 0.7 | -0.7 | 0.3 | -0.0 | -0.2 | 0.5 | 0.5 | -0.3 | 0.3 |
Locomotion velocity, hab. session 2 | 0.4 | 0.5 | 1.7 | 0.8 | -0.7 | 0.7 | -0.7 | 0.3 | 0.7 | -0.1 | -0.7 | 0.2 | -0.4 | 0.2 | -1.0 | 0.0 | -0.6 | 0.4 | 1.1 | -0.6 | -0.5 | 0.2 | -0.9 | 0.4 | 1.3 | -1.3 | 1.0 | -1.3 | 0.9 | -0.8 | 1.2 | 1.1 | 1.0 | -0.2 | 1.0 | -0.3 | -0.6 | 0.6 | 1.1 | -0.6 | 1.1 | 0.3 | 0.6 | -0.6 | -0.9 | 0.2 | 0.8 | 0.3 | 1.1 | -0.6 | 0.9 | -0.7 | 0.3 | 0.3 | -0.3 | 0.3 | 0.6 | -0.3 | 0.4 |
Total locomotion distance, NPP test | 0.4 | 0.6 | 3.1 | -0.0 | 0.1 | -0.1 | 0.1 | 0.5 | -0.1 | 1.1 | 0.1 | -1.3 | -1.3 | -0.4 | 0.2 | -0.4 | 0.1 | 0.2 | -0.3 | 0.1 | -0.9 | -1.1 | 0.1 | -1.3 | 1.3 | -1.1 | 1.1 | -1.1 | 1.6 | 0.2 | 0.8 | 1.7 | -0.7 | 1.0 | -0.6 | -0.5 | 0.1 | -0.2 | 0.2 | 0.1 | 0.2 | -1.3 | -0.3 | 0.1 | -0.4 | 0.3 | -0.1 | 1.0 | 0.5 | 0.1 | -0.1 | 0.3 | 0.5 | -1.3 | 1.0 | 1.4 | -0.1 | -0.5 | -0.6 |
Locomotion velocity, NPP test | 0.4 | 0.6 | 2.4 | -0.3 | 0.3 | -0.3 | 0.3 | 0.8 | -0.3 | 0.8 | 0.3 | -1.2 | -1.5 | -0.7 | 0.5 | -0.7 | 0.3 | 0.5 | -0.4 | 0.3 | -0.6 | -1.2 | 0.4 | -1.2 | 1.0 | -0.8 | 0.8 | -0.8 | 1.2 | 0.4 | 0.4 | 1.5 | -0.6 | 1.2 | -0.6 | -0.8 | 0.4 | 0.1 | -0.1 | 0.4 | -0.1 | -1.2 | -0.6 | 0.3 | -0.1 | 0.6 | -0.3 | 0.6 | 0.1 | 0.3 | -0.4 | 0.6 | 0.8 | -1.2 | 1.2 | 1.5 | -0.3 | -0.8 | -0.8 |
Pavlov. Cond. magazine entry latency | 0.4 | 0.5 | 1.4 | -0.8 | 0.7 | -0.7 | 0.7 | 0.8 | -0.7 | 0.3 | 0.7 | -0.6 | -1.1 | -0.9 | 1.0 | -0.9 | 0.7 | 0.7 | -0.7 | 0.7 | 0.3 | -1.0 | 0.9 | -0.8 | -0.1 | 0.3 | -0.2 | 0.2 | -0.1 | 0.8 | -0.5 | 0.2 | -0.7 | 1.2 | -0.7 | -0.8 | 0.7 | 0.4 | -0.8 | 0.7 | -0.8 | -0.8 | -0.9 | 0.7 | 0.5 | 0.8 | -0.8 | -0.1 | -0.7 | 0.7 | -0.8 | 0.9 | 0.8 | -0.8 | 1.1 | 1.0 | -0.7 | -0.8 | -1.0 |
Pavlov. Cond. lever contacts | 0.4 | 0.5 | 2.3 | -0.6 | 0.4 | -0.4 | 0.4 | 0.7 | -0.4 | 0.9 | 0.4 | -1.1 | -1.3 | -0.7 | 0.4 | -0.7 | 0.4 | 0.5 | -0.5 | 0.4 | -0.3 | -1.2 | 0.2 | -1.1 | 0.7 | -0.5 | 0.5 | -0.6 | 0.9 | 0.5 | 0.3 | 1.0 | -0.7 | 1.5 | -0.6 | -0.7 | 0.4 | 0.1 | -0.2 | 0.4 | -0.1 | -1.1 | -0.6 | 0.4 | -0.0 | 0.6 | -0.4 | 0.5 | -0.1 | 0.4 | -0.5 | 0.2 | 0.7 | -1.2 | 0.8 | 1.4 | -0.4 | -0.7 | -0.8 |
Bone: elastic displacement | 0.4 | 0.4 | 2.4 | -0.1 | 0.1 | -0.1 | 0.1 | 0.3 | -0.1 | 1.1 | 0.1 | -1.2 | -1.6 | -0.4 | 0.1 | -0.5 | 0.1 | 0.0 | -0.3 | 0.1 | -0.8 | -1.1 | 0.2 | -1.2 | 0.9 | -0.6 | 0.7 | -0.6 | 0.3 | 0.2 | 0.4 | 1.3 | -0.7 | 1.2 | -0.7 | -0.4 | 0.1 | 0.1 | -0.3 | 0.1 | -0.3 | -1.1 | -0.5 | 0.1 | -0.3 | 0.2 | -0.1 | 0.8 | -0.6 | 0.1 | -0.2 | 0.2 | 0.3 | -1.2 | 0.8 | 1.3 | -0.1 | -0.4 | -1.2 |
Bone: maximum diameter | 0.4 | 0.8 | 1.1 | -1.0 | 1.0 | -1.0 | 1.0 | 0.9 | -1.0 | -0.3 | 1.0 | -0.6 | -0.8 | -0.9 | 0.9 | -1.0 | 1.0 | 0.7 | -0.8 | 1.0 | 0.7 | -0.9 | 0.9 | -0.4 | -0.9 | 0.9 | -0.9 | 0.9 | -0.6 | 1.0 | -1.0 | -0.3 | -0.6 | 0.8 | -0.6 | -1.0 | 1.0 | 0.4 | -1.1 | 1.0 | -1.1 | -0.5 | -1.0 | 1.0 | 1.0 | 0.9 | -0.9 | -0.6 | -0.9 | 1.0 | -1.0 | 0.9 | 0.9 | -0.5 | 0.9 | 0.9 | -1.0 | -1.0 | -0.9 |
Delay disc. indifference point, 0s delay | 0.4 | 0.5 | 2.3 | -0.5 | 0.4 | -0.4 | 0.4 | -0.4 | -0.4 | 1.4 | 0.4 | -1.4 | 0.0 | 0.1 | 0.4 | 0.2 | 0.4 | -0.9 | -1.3 | 0.4 | -0.5 | -0.7 | 0.2 | -1.1 | -0.2 | 0.4 | -0.1 | 0.3 | 0.8 | 0.5 | -0.3 | -0.0 | -1.5 | 0.6 | -1.5 | 0.5 | 0.3 | -1.5 | -0.1 | 0.3 | -0.1 | -1.3 | -0.4 | 0.4 | 0.4 | -0.4 | -0.5 | 0.5 | -0.3 | 0.3 | -0.6 | 0.4 | -0.4 | -1.1 | 0.4 | 0.4 | -0.3 | 0.5 | -0.5 |
Delay disc. indifference point, 24s delay | 0.4 | 0.4 | 1.6 | 0.6 | -0.4 | 0.4 | -0.4 | -1.1 | 0.4 | 0.0 | -0.4 | 0.4 | 0.9 | 1.1 | -0.5 | 1.0 | -0.6 | -1.1 | -0.1 | -0.6 | -0.6 | 0.8 | -0.6 | -0.2 | 0.1 | -0.2 | 0.3 | -0.2 | 0.2 | -0.7 | 0.2 | -0.0 | -0.2 | -0.8 | -0.2 | 1.0 | -0.3 | -1.3 | 0.5 | -0.3 | 0.5 | 0.4 | 0.6 | -0.6 | -0.5 | -1.1 | 0.6 | 0.6 | 0.6 | -0.4 | 0.5 | -0.7 | -1.1 | -0.2 | -0.8 | -0.7 | 0.4 | 1.0 | 0.8 |
Food seeking constrained by brief footshock | 0.4 | 0.4 | 2.6 | 0.2 | -0.1 | 0.1 | -0.1 | -0.2 | 0.1 | 1.0 | -0.1 | -0.9 | -0.8 | 0.0 | -0.3 | 0.0 | -0.2 | -0.3 | -0.1 | -0.2 | -1.0 | -0.7 | -0.6 | -1.2 | 1.1 | -1.0 | 1.1 | -1.1 | 1.5 | -0.2 | 1.0 | 1.6 | -0.5 | 0.8 | -0.4 | 0.0 | -0.2 | -0.5 | 0.6 | -0.2 | 0.6 | -0.9 | 0.1 | -0.2 | -0.6 | -0.2 | 0.2 | 1.2 | 0.6 | -0.3 | 0.2 | -0.6 | -0.2 | -1.2 | 0.1 | 0.9 | 0.3 | 0.0 | -0.2 |
Seeking ratio, punishment vs. effort | 0.4 | 0.5 | 2.4 | 0.3 | -0.3 | 0.3 | -0.3 | -0.4 | 0.3 | 1.4 | -0.3 | -1.0 | -0.6 | 0.3 | -0.4 | 0.3 | -0.2 | -0.6 | -0.2 | -0.2 | -1.3 | -0.6 | -0.6 | -0.8 | 1.3 | -1.0 | 1.2 | -1.1 | 1.6 | -0.3 | 0.9 | 1.3 | -0.6 | 0.6 | -0.5 | 0.4 | -0.3 | -0.7 | 0.6 | -0.3 | 0.6 | -1.0 | 0.2 | -0.2 | -0.6 | -0.5 | 0.3 | 1.3 | 0.5 | -0.3 | 0.1 | -0.4 | -0.4 | -0.7 | 0.1 | 0.7 | 0.3 | 0.4 | -0.2 |
Na content in liver | 0.4 | 0.5 | 1.5 | -0.7 | 0.7 | -0.7 | 0.7 | 0.1 | -0.7 | -0.4 | 0.7 | 0.0 | 0.5 | -0.3 | 0.9 | -0.2 | 0.7 | 0.0 | -0.9 | 0.7 | 0.8 | -0.0 | 0.8 | -0.0 | -1.2 | 1.1 | -1.0 | 1.1 | -0.6 | 0.7 | -1.1 | -1.2 | -0.6 | -0.0 | -0.6 | -0.0 | 0.8 | -0.5 | -0.8 | 0.8 | -0.8 | 0.0 | -0.5 | 0.7 | 1.0 | 0.2 | -0.9 | -0.8 | -0.6 | 0.7 | -0.7 | 0.9 | 0.1 | 0.0 | 0.3 | -0.3 | -0.7 | -0.0 | -0.0 |
Rb content in liver | 0.4 | 0.5 | 1.0 | 0.8 | -0.7 | 0.7 | -0.7 | -0.7 | 0.7 | -0.3 | -0.7 | 0.9 | 0.9 | 0.7 | -0.6 | 0.7 | -0.8 | -0.4 | 0.8 | -0.8 | -0.0 | 1.0 | -0.7 | 0.8 | 0.1 | -0.3 | 0.2 | -0.3 | -0.1 | -0.8 | 0.4 | -0.2 | 0.8 | -1.0 | 0.8 | 0.6 | -0.7 | -0.0 | 0.6 | -0.7 | 0.6 | 0.9 | 0.8 | -0.8 | -0.5 | -0.6 | 0.6 | 0.1 | 0.7 | -0.7 | 0.8 | -0.7 | -0.7 | 0.8 | -0.9 | -0.9 | 0.7 | 0.6 | 0.9 |
BMI with tail | 0.3 | 0.9 | 4.2 | 1.1 | -1.0 | 1.0 | -1.0 | 0.4 | 1.0 | -0.7 | -1.0 | 0.9 | -0.8 | -0.0 | -0.6 | -0.2 | -0.9 | 0.8 | 2.0 | -0.9 | -0.3 | 0.4 | -0.4 | 1.0 | 1.1 | -1.3 | 0.8 | -1.2 | -0.6 | -1.0 | 1.1 | 1.1 | 1.8 | -0.4 | 1.9 | -0.5 | -1.0 | 2.0 | 0.2 | -1.0 | 0.2 | 1.0 | 0.7 | -0.9 | -1.1 | 0.4 | 1.0 | 0.0 | 0.2 | -1.1 | 1.1 | -0.5 | 0.4 | 0.9 | -0.3 | 0.0 | 1.1 | -0.5 | -0.1 |
Body weight | 0.3 | 1.3 | 5.3 | 1.3 | -1.2 | 1.2 | -1.2 | 0.3 | 1.2 | -0.6 | -1.2 | 1.3 | -0.3 | 0.3 | -1.0 | 0.0 | -1.2 | 0.7 | 2.3 | -1.2 | -0.3 | 0.8 | -1.1 | 1.3 | 1.4 | -1.5 | 1.0 | -1.4 | -0.1 | -1.4 | 1.5 | 1.1 | 2.2 | -0.6 | 2.3 | -0.5 | -1.2 | 2.0 | 1.1 | -1.2 | 1.0 | 1.4 | 1.0 | -1.2 | -1.3 | 0.3 | 1.3 | 0.1 | 0.9 | -1.2 | 1.5 | -1.0 | 0.3 | 1.2 | -0.7 | -0.2 | 1.2 | -0.5 | 0.5 |
Glucose | 0.3 | 0.4 | 1.5 | 0.5 | -0.5 | 0.5 | -0.5 | -0.7 | 0.5 | 1.2 | -0.5 | -1.0 | -0.2 | 0.6 | -0.7 | 0.5 | -0.5 | -0.9 | -0.0 | -0.5 | -1.1 | -0.2 | -0.6 | -0.7 | 1.0 | -0.8 | 1.0 | -0.9 | 0.9 | -0.4 | 0.8 | 1.0 | -0.5 | 0.1 | -0.4 | 0.7 | -0.6 | -1.0 | 0.7 | -0.6 | 0.6 | -0.6 | 0.3 | -0.5 | -0.8 | -0.8 | 0.4 | 1.2 | 0.2 | -0.5 | 0.4 | -0.5 | -0.7 | -0.8 | -0.1 | 0.2 | 0.5 | 0.7 | -0.2 |
Liver weight, right | 0.3 | 0.4 | 1.3 | 0.7 | -0.6 | 0.6 | -0.6 | -0.7 | 0.6 | -0.1 | -0.6 | 0.8 | 1.1 | 0.7 | -0.5 | 0.8 | -0.7 | -0.5 | 0.6 | -0.7 | -0.1 | 1.0 | -0.6 | 0.9 | 0.0 | -0.2 | 0.1 | -0.2 | 0.1 | -0.7 | 0.3 | -0.5 | 0.7 | -1.0 | 0.7 | 0.7 | -0.7 | -0.2 | 0.6 | -0.7 | 0.6 | 0.9 | 0.8 | -0.7 | -0.4 | -0.7 | 0.6 | -0.0 | 0.7 | -0.6 | 0.7 | -0.5 | -0.7 | 0.9 | -0.8 | -1.1 | 0.6 | 0.7 | 1.0 |
Food consumed during 24 hour testing period | 0.3 | 0.3 | 1.9 | 0.0 | -0.5 | 0.5 | -0.5 | 0.1 | 0.5 | 0.9 | -0.5 | -0.4 | -1.4 | -0.3 | -0.2 | -0.2 | -0.5 | 0.0 | 0.4 | -0.5 | -0.6 | -0.6 | -0.1 | -0.6 | 1.1 | -1.0 | 1.0 | -1.0 | 0.2 | -0.2 | 0.8 | 1.3 | -0.0 | 0.6 | 0.0 | -0.1 | -0.4 | 0.8 | -0.2 | -0.4 | -0.2 | -0.6 | -0.0 | -0.5 | -0.9 | -0.1 | 0.2 | 1.1 | -0.3 | -0.4 | 0.3 | -0.1 | 0.1 | -0.4 | 0.5 | 0.9 | 0.4 | -0.1 | -0.9 |
Std. dev. time between licks in bursts | 0.3 | 0.3 | 0.7 | -0.7 | 0.6 | -0.6 | 0.6 | 0.4 | -0.6 | 0.5 | 0.6 | -0.8 | -0.7 | -0.5 | 0.3 | -0.5 | 0.7 | 0.2 | -0.8 | 0.7 | 0.0 | -0.8 | 0.5 | -0.7 | -0.2 | 0.4 | -0.2 | 0.3 | 0.1 | 0.7 | -0.4 | 0.3 | -0.8 | 0.5 | -0.8 | -0.4 | 0.6 | -0.2 | -0.6 | 0.6 | -0.6 | -0.7 | -0.7 | 0.7 | 0.5 | 0.4 | -0.7 | -0.0 | -0.6 | 0.6 | -0.7 | 0.4 | 0.4 | -0.8 | 0.6 | 0.7 | -0.6 | -0.4 | -0.8 |
Water consumed over 24 hours | 0.3 | 0.3 | 1.4 | -0.3 | 0.2 | -0.2 | 0.2 | -0.2 | -0.2 | 0.8 | 0.2 | -0.9 | -0.9 | -0.1 | 0.4 | -0.1 | 0.2 | -0.5 | -0.7 | 0.2 | -0.7 | -0.8 | 0.6 | -1.2 | 0.1 | 0.0 | 0.2 | -0.1 | -0.0 | 0.3 | -0.2 | 0.6 | -1.1 | 0.6 | -1.1 | 0.2 | 0.2 | -0.4 | -0.8 | 0.2 | -0.8 | -1.2 | -0.5 | 0.2 | -0.1 | -0.2 | -0.3 | 0.8 | -0.9 | 0.2 | -0.4 | 0.7 | -0.2 | -1.0 | 0.9 | 0.7 | -0.2 | 0.2 | -1.0 |
Indifference point 0 sec | 0.3 | 0.5 | 2.2 | -0.6 | 0.5 | -0.5 | 0.5 | 0.4 | -0.5 | -1.1 | 0.5 | 1.0 | 1.0 | -0.4 | 0.1 | -0.2 | 0.5 | 0.6 | -0.2 | 0.5 | 1.5 | 0.5 | 0.3 | 0.8 | -1.1 | 1.0 | -1.1 | 1.0 | -0.5 | 0.6 | -0.8 | -1.4 | 0.4 | -0.4 | 0.3 | -0.3 | 0.6 | 0.2 | -0.1 | 0.6 | -0.1 | 0.8 | -0.2 | 0.5 | 0.9 | 0.5 | -0.7 | -1.4 | 0.4 | 0.5 | -0.4 | 0.2 | 0.4 | 0.9 | -0.3 | -0.6 | -0.5 | -0.3 | 0.9 |
Indifference point function ln k | 0.3 | 0.4 | 1.7 | 0.7 | -0.7 | 0.7 | -0.7 | -0.1 | 0.7 | -0.7 | -0.7 | 1.0 | -0.0 | 0.2 | -0.6 | 0.2 | -0.8 | 0.3 | 1.3 | -0.8 | 0.1 | 0.7 | -0.4 | 1.0 | 0.4 | -0.5 | 0.3 | -0.5 | -0.8 | -0.7 | 0.5 | 0.3 | 1.3 | -0.7 | 1.3 | 0.0 | -0.7 | 0.9 | 0.3 | -0.7 | 0.3 | 1.0 | 0.6 | -0.8 | -0.7 | -0.1 | 0.7 | 0.0 | 0.2 | -0.7 | 0.9 | -0.4 | -0.1 | 0.8 | -0.5 | -0.4 | 0.7 | 0.0 | 0.3 |
Indifference point function log k | 0.3 | 0.4 | 1.7 | 0.7 | -0.7 | 0.7 | -0.7 | -0.1 | 0.7 | -0.7 | -0.7 | 1.0 | -0.0 | 0.2 | -0.6 | 0.2 | -0.8 | 0.3 | 1.3 | -0.8 | 0.1 | 0.7 | -0.4 | 1.0 | 0.4 | -0.5 | 0.3 | -0.5 | -0.8 | -0.7 | 0.5 | 0.3 | 1.3 | -0.7 | 1.3 | 0.0 | -0.7 | 0.9 | 0.3 | -0.7 | 0.3 | 1.0 | 0.6 | -0.8 | -0.7 | -0.1 | 0.7 | 0.0 | 0.2 | -0.7 | 0.9 | -0.4 | -0.1 | 0.8 | -0.5 | -0.4 | 0.7 | 0.0 | 0.3 |
Delay discounting total patch changes 24 sec | 0.3 | 0.4 | 2.7 | 0.2 | -0.1 | 0.1 | -0.1 | -0.5 | 0.1 | -0.5 | -0.1 | 1.0 | 1.6 | 0.7 | -0.6 | 0.7 | -0.1 | -0.5 | -0.1 | -0.1 | 0.4 | 1.0 | -0.6 | 0.8 | -0.6 | 0.5 | -0.6 | 0.6 | 0.2 | -0.3 | -0.3 | -1.2 | 0.2 | -1.1 | 0.2 | 0.6 | -0.1 | -0.5 | 0.6 | -0.1 | 0.6 | 0.8 | 0.5 | -0.1 | 0.3 | -0.4 | 0.2 | -0.6 | 0.6 | -0.1 | 0.2 | -0.5 | -0.5 | 1.0 | -1.0 | -1.2 | 0.1 | 0.6 | 1.2 |
Delay discounting total patch changes 6 sec | 0.3 | 0.5 | 2.2 | 0.5 | -0.5 | 0.5 | -0.5 | -0.6 | 0.5 | -0.2 | -0.5 | 1.0 | 1.5 | 0.7 | -0.7 | 0.8 | -0.5 | -0.4 | 0.4 | -0.5 | 0.2 | 1.1 | -0.8 | 0.9 | -0.0 | -0.1 | 0.0 | -0.1 | 0.5 | -0.4 | 0.3 | -0.7 | 0.6 | -0.9 | 0.6 | 0.6 | -0.4 | -0.3 | 1.1 | -0.4 | 1.0 | 0.9 | 0.8 | -0.5 | -0.2 | -0.5 | 0.4 | -0.2 | 1.2 | -0.5 | 0.6 | -0.8 | -0.6 | 1.1 | -1.1 | -1.1 | 0.5 | 0.6 | 1.5 |
Locomotor activity | 0.3 | 0.5 | 1.9 | 0.5 | -0.6 | 0.6 | -0.6 | 0.2 | 0.6 | -0.8 | -0.6 | 1.3 | 0.6 | 0.2 | -0.9 | 0.1 | -0.5 | 0.6 | 1.1 | -0.5 | 0.5 | 0.8 | -0.8 | 1.2 | 0.3 | -0.4 | 0.1 | -0.3 | -0.3 | -0.5 | 0.4 | -0.2 | 1.4 | -0.6 | 1.4 | -0.2 | -0.3 | 1.1 | 0.9 | -0.3 | 0.8 | 1.2 | 0.6 | -0.5 | -0.3 | 0.2 | 0.5 | -0.6 | 0.8 | -0.4 | 0.6 | -0.8 | 0.2 | 1.2 | -0.9 | -0.6 | 0.4 | -0.2 | 0.8 |
Social time | 0.3 | 0.4 | 1.6 | -0.4 | 0.2 | -0.2 | 0.2 | 1.0 | -0.2 | 0.2 | 0.2 | -0.6 | -1.3 | -0.7 | -0.0 | -0.8 | 0.3 | 0.9 | 0.1 | 0.3 | -0.1 | -0.9 | -0.1 | -0.7 | 0.8 | -0.7 | 0.5 | -0.7 | 0.9 | 0.4 | 0.6 | 1.2 | 0.0 | 1.1 | 0.1 | -1.0 | 0.3 | 0.7 | 0.0 | 0.3 | 0.0 | -0.6 | -0.4 | 0.3 | -0.1 | 0.9 | -0.3 | 0.1 | 0.4 | 0.2 | -0.2 | -0.3 | 1.0 | -0.8 | 0.5 | 1.3 | -0.2 | -1.0 | -0.5 |
Pavlov. Cond. latency score | 0.3 | 0.4 | 1.0 | -0.7 | 0.7 | -0.7 | 0.7 | 1.0 | -0.7 | -0.6 | 0.7 | -0.2 | -0.8 | -0.9 | 0.5 | -0.9 | 0.7 | 1.0 | -0.3 | 0.7 | 0.6 | -0.7 | 0.5 | -0.1 | -0.4 | 0.5 | -0.5 | 0.5 | -0.4 | 0.7 | -0.5 | -0.1 | -0.1 | 0.7 | -0.1 | -1.0 | 0.7 | 0.8 | -0.3 | 0.7 | -0.5 | -0.2 | -0.7 | 0.7 | 0.7 | 0.9 | -0.6 | -0.6 | -0.5 | 0.7 | -0.6 | 0.5 | 1.0 | -0.2 | 0.6 | 0.8 | -0.7 | -1.0 | -0.7 |
Progressive ratio test 2 breakpoint | 0.3 | 0.4 | 1.3 | -0.4 | 0.2 | -0.2 | 0.2 | 0.5 | -0.2 | -1.0 | 0.2 | 0.6 | 0.1 | -0.5 | 0.4 | -0.5 | 0.4 | 0.8 | 0.2 | 0.4 | 1.1 | 0.1 | 0.7 | 0.6 | -1.0 | 0.9 | -1.1 | 0.9 | -1.1 | 0.4 | -0.8 | -0.8 | 0.5 | -0.2 | 0.5 | -0.5 | 0.4 | 1.0 | -0.6 | 0.4 | -0.6 | 0.6 | -0.3 | 0.4 | 0.7 | 0.7 | -0.4 | -1.1 | -0.6 | 0.4 | -0.3 | 0.4 | 0.5 | 0.6 | 0.1 | -0.2 | -0.4 | -0.5 | -0.2 |
Short access total locomotion | 0.3 | 0.3 | 1.2 | 0.4 | -0.2 | 0.2 | -0.2 | -0.5 | 0.2 | -0.6 | -0.2 | 0.9 | 1.1 | 0.5 | -0.4 | 0.7 | -0.3 | -0.4 | 0.1 | -0.3 | 0.4 | 0.9 | -0.4 | 0.9 | -0.3 | 0.3 | -0.2 | 0.3 | 0.1 | -0.3 | 0.0 | -0.9 | 0.3 | -0.9 | 0.3 | 0.6 | -0.4 | -0.7 | 0.5 | -0.4 | 0.5 | 0.9 | 0.5 | -0.3 | 0.0 | -0.6 | 0.4 | -0.4 | 0.6 | -0.4 | 0.4 | -0.5 | -0.5 | 0.9 | -0.8 | -1.0 | 0.4 | 0.6 | 1.0 |
Stereotopy head waving bouts, day 7 | 0.3 | 0.4 | 1.2 | 0.6 | -0.5 | 0.5 | -0.5 | 0.2 | 0.5 | 0.1 | -0.5 | 0.1 | -0.0 | 0.3 | -0.8 | 0.1 | -0.4 | 0.3 | 0.8 | -0.4 | -0.3 | 0.2 | -1.0 | 0.3 | 1.1 | -1.0 | 0.8 | -1.0 | 1.0 | -0.5 | 1.0 | 0.7 | 0.7 | 0.0 | 0.7 | -0.2 | -0.5 | 0.3 | 1.1 | -0.5 | 1.0 | 0.3 | 0.5 | -0.4 | -0.6 | 0.1 | 0.6 | 0.2 | 1.1 | -0.4 | 0.6 | -1.0 | 0.2 | 0.2 | -0.6 | 0.2 | 0.4 | -0.2 | 0.6 |
Condit. Reinf. inactive responses | 0.3 | 0.3 | 1.3 | 0.3 | -0.5 | 0.5 | -0.5 | -0.7 | 0.5 | 1.1 | -0.5 | -0.9 | -0.3 | 0.4 | 0.1 | 0.5 | -0.5 | -0.8 | -0.1 | -0.5 | -0.8 | -0.1 | 0.1 | -0.6 | 0.5 | -0.4 | 0.6 | -0.5 | 0.3 | -0.3 | 0.4 | 0.9 | -0.5 | -0.4 | -0.5 | 0.8 | -0.5 | -1.0 | -0.2 | -0.5 | -0.1 | -0.6 | 0.2 | -0.5 | -0.7 | -0.8 | 0.2 | 1.0 | -0.3 | -0.5 | 0.2 | 0.1 | -0.7 | -0.8 | 0.3 | 0.0 | 0.5 | 0.8 | -0.4 |
Novel to familiar place preference ratio | 0.3 | 0.4 | 2.1 | 0.0 | 0.1 | -0.1 | 0.1 | 0.8 | -0.1 | -1.5 | 0.1 | 0.9 | -0.1 | -0.5 | -0.2 | -0.6 | 0.1 | 1.1 | 0.8 | 0.1 | 1.0 | 0.3 | -0.1 | 1.1 | -0.4 | 0.3 | -0.5 | 0.3 | -0.9 | 0.1 | -0.1 | -0.4 | 1.2 | -0.1 | 1.2 | -0.9 | 0.1 | 1.3 | 0.1 | 0.1 | 0.1 | 1.1 | -0.0 | 0.1 | 0.2 | 0.8 | 0.0 | -1.0 | -0.0 | 0.1 | 0.1 | -0.1 | 0.8 | 0.9 | -0.2 | -0.1 | -0.1 | -0.9 | 0.1 |
Time in novel zone, NPP test | 0.3 | 0.3 | 1.9 | 0.3 | -0.2 | 0.2 | -0.2 | 0.3 | 0.2 | -1.4 | -0.2 | 1.1 | 0.4 | -0.1 | -0.5 | -0.1 | -0.2 | 0.6 | 0.9 | -0.2 | 0.8 | 0.7 | -0.4 | 1.2 | -0.3 | 0.1 | -0.4 | 0.2 | -0.7 | -0.2 | 0.0 | -0.5 | 1.2 | -0.6 | 1.2 | -0.3 | -0.2 | 0.8 | 0.3 | -0.2 | 0.3 | 1.2 | 0.3 | -0.2 | 0.0 | 0.3 | 0.3 | -0.8 | 0.3 | -0.2 | 0.4 | -0.4 | 0.3 | 1.0 | -0.6 | -0.6 | 0.2 | -0.3 | 0.6 |
Pavlov. Cond. change in total contacts | 0.3 | 0.3 | 1.6 | -0.1 | -0.0 | 0.0 | -0.0 | 0.4 | 0.0 | 1.0 | -0.0 | -0.8 | -0.9 | -0.3 | -0.0 | -0.4 | 0.0 | 0.3 | -0.1 | 0.0 | -0.4 | -0.7 | -0.3 | -0.8 | 1.0 | -0.8 | 0.8 | -0.8 | 1.0 | 0.1 | 0.7 | 1.0 | -0.3 | 1.3 | -0.2 | -0.4 | 0.1 | 0.1 | 0.4 | 0.1 | 0.4 | -0.8 | -0.2 | 0.0 | -0.4 | 0.3 | -0.1 | 0.6 | 0.4 | 0.0 | -0.1 | -0.2 | 0.4 | -0.8 | 0.4 | 1.0 | -0.0 | -0.4 | -0.4 |
Diff in mean of infusions in LGA sessions | 0.3 | 0.4 | 1.5 | 0.4 | -0.3 | 0.3 | -0.3 | -0.4 | 0.3 | 1.1 | -0.3 | -0.6 | -0.2 | 0.5 | -0.4 | 0.5 | -0.3 | -0.7 | -0.1 | -0.3 | -1.2 | -0.2 | -0.5 | -0.7 | 1.2 | -0.9 | 1.1 | -1.0 | 1.2 | -0.5 | 0.9 | 0.9 | -0.5 | 0.5 | -0.4 | 0.5 | -0.2 | -0.9 | 0.6 | -0.2 | 0.6 | -0.6 | 0.3 | -0.3 | -0.7 | -0.6 | 0.4 | 1.2 | 0.6 | -0.4 | 0.3 | -0.8 | -0.4 | -0.7 | -0.2 | 0.2 | 0.4 | 0.5 | 0.2 |
Time in closed arm after self-admin | 0.3 | 0.3 | 1.4 | 0.2 | -0.2 | 0.2 | -0.2 | -0.3 | 0.2 | -1.0 | -0.2 | 1.2 | 0.8 | 0.2 | -0.3 | 0.3 | -0.2 | -0.1 | 0.4 | -0.2 | 0.7 | 0.8 | 0.3 | 1.0 | -0.8 | 0.5 | -0.6 | 0.6 | -1.1 | -0.2 | -0.4 | -1.0 | 0.6 | -0.9 | 0.5 | 0.4 | -0.2 | 0.0 | -0.3 | -0.2 | -0.3 | 0.9 | 0.3 | -0.2 | 0.2 | -0.3 | 0.2 | -0.6 | -0.3 | -0.3 | 0.2 | 0.1 | -0.3 | 1.0 | -0.4 | -1.0 | 0.3 | 0.4 | 0.3 |
Run reversals in cocaine runway, females | 0.3 | 0.3 | 1.2 | 0.4 | -0.3 | 0.3 | -0.3 | -0.5 | 0.3 | 0.9 | -0.3 | -0.6 | -0.1 | 0.5 | -0.3 | 0.5 | -0.2 | -0.8 | -0.3 | -0.2 | -1.1 | -0.2 | -0.1 | -0.8 | 0.7 | -0.6 | 0.7 | -0.6 | 1.0 | -0.4 | 0.5 | 0.6 | -0.7 | 0.1 | -0.7 | 0.6 | -0.3 | -0.9 | 0.1 | -0.3 | 0.1 | -0.7 | 0.2 | -0.2 | -0.5 | -0.6 | 0.4 | 0.9 | 0.2 | -0.2 | 0.1 | -0.0 | -0.5 | -0.7 | 0.1 | 0.2 | 0.2 | 0.6 | -0.0 |
Sr content in liver | 0.3 | 0.3 | 1.0 | 0.5 | -0.6 | 0.6 | -0.6 | -0.0 | 0.6 | 0.1 | -0.6 | 0.1 | -0.2 | 0.2 | -0.6 | 0.1 | -0.5 | 0.1 | 0.9 | -0.5 | -0.5 | 0.1 | -0.6 | 0.2 | 0.9 | -0.9 | 0.8 | -0.9 | 0.6 | -0.5 | 0.9 | 1.0 | 0.7 | -0.2 | 0.8 | -0.1 | -0.6 | 0.6 | 0.6 | -0.6 | 0.6 | 0.2 | 0.5 | -0.5 | -0.8 | 0.1 | 0.5 | 0.5 | 0.6 | -0.6 | 0.6 | -0.6 | -0.0 | 0.2 | -0.3 | 0.1 | 0.6 | -0.1 | 0.2 |
Heart weight | 0.2 | 0.3 | 1.2 | 0.4 | -0.5 | 0.5 | -0.5 | -0.5 | 0.5 | -0.1 | -0.5 | 0.4 | 0.8 | 0.6 | -0.5 | 0.6 | -0.4 | -0.4 | 0.3 | -0.4 | 0.1 | 0.6 | -1.0 | 0.3 | 0.4 | -0.4 | 0.4 | -0.4 | 0.6 | -0.4 | 0.4 | -0.1 | 0.3 | -0.5 | 0.4 | 0.4 | -0.4 | -0.5 | 1.1 | -0.4 | 1.0 | 0.2 | 0.6 | -0.4 | -0.3 | -0.5 | 0.4 | 0.2 | 1.0 | -0.3 | 0.5 | -0.9 | -0.5 | 0.3 | -0.8 | -0.3 | 0.3 | 0.4 | 1.0 |
Retroperitoneal fat weight | 0.2 | 0.7 | 3.1 | 0.8 | -0.8 | 0.8 | -0.8 | -0.5 | 0.8 | -0.9 | -0.8 | 1.8 | 1.1 | 0.5 | -0.6 | 0.6 | -0.7 | -0.0 | 1.2 | -0.7 | 0.5 | 1.3 | -0.9 | 1.5 | 0.0 | -0.3 | 0.1 | -0.2 | -0.5 | -0.8 | 0.4 | -0.6 | 1.4 | -1.3 | 1.4 | 0.3 | -0.8 | 0.8 | 0.7 | -0.8 | 0.8 | 1.4 | 0.9 | -0.7 | -0.4 | -0.3 | 0.7 | -0.4 | 0.7 | -0.7 | 0.9 | -0.6 | -0.5 | 1.6 | -1.1 | -1.1 | 0.7 | 0.3 | 1.1 |
Delay discounting total patch changes 0 sec | 0.2 | 0.4 | 1.8 | -0.2 | 0.2 | -0.2 | 0.2 | 0.1 | -0.2 | -1.1 | 0.2 | 1.2 | 1.3 | -0.0 | -0.3 | 0.1 | 0.1 | 0.3 | 0.1 | 0.1 | 1.3 | 0.9 | -0.2 | 1.0 | -0.9 | 0.7 | -0.8 | 0.7 | -0.3 | 0.3 | -0.5 | -1.3 | 0.6 | -0.8 | 0.6 | -0.0 | 0.2 | 0.1 | 0.3 | 0.2 | 0.3 | 1.1 | 0.2 | 0.1 | 0.6 | 0.2 | -0.3 | -1.1 | 0.7 | 0.2 | -0.0 | -0.2 | 0.1 | 1.1 | -0.7 | -0.9 | -0.2 | -0.0 | 1.2 |
Delay discounting water rate 0 sec | 0.2 | 0.3 | 1.4 | -0.1 | 0.2 | -0.2 | 0.2 | 0.1 | -0.2 | -1.1 | 0.2 | 1.0 | 0.9 | 0.1 | -0.2 | 0.1 | 0.2 | 0.2 | 0.1 | 0.2 | 0.9 | 0.7 | -0.1 | 0.8 | -1.0 | 0.8 | -1.0 | 0.9 | -1.1 | 0.1 | -0.7 | -1.2 | 0.4 | -0.7 | 0.4 | 0.0 | 0.3 | 0.3 | -0.1 | 0.3 | -0.1 | 0.9 | 0.0 | 0.2 | 0.6 | 0.2 | -0.1 | -1.1 | -0.1 | 0.2 | -0.1 | -0.1 | 0.1 | 0.9 | -0.6 | -0.8 | -0.2 | 0.0 | 0.5 |
Locomotor testing distance | 0.2 | 0.3 | 1.0 | 0.6 | -0.5 | 0.5 | -0.5 | 0.2 | 0.5 | -0.6 | -0.5 | 0.9 | 0.3 | 0.3 | -1.0 | 0.1 | -0.5 | 0.3 | 0.9 | -0.5 | 0.0 | 0.5 | -0.7 | 0.7 | 0.6 | -0.6 | 0.4 | -0.6 | 0.1 | -0.6 | 0.5 | 0.2 | 1.0 | -0.4 | 1.0 | -0.1 | -0.3 | 0.9 | 0.8 | -0.3 | 0.7 | 0.7 | 0.5 | -0.5 | -0.5 | 0.1 | 0.6 | -0.1 | 0.8 | -0.3 | 0.6 | -0.7 | 0.2 | 0.8 | -0.6 | -0.2 | 0.3 | -0.1 | 0.6 |
Social response proportion | 0.2 | 0.2 | 0.4 | 0.5 | -0.6 | 0.6 | -0.6 | -0.4 | 0.6 | 0.5 | -0.6 | 0.1 | -0.2 | 0.3 | -0.3 | 0.3 | -0.5 | -0.4 | 0.4 | -0.5 | -0.6 | 0.1 | 0.1 | 0.0 | 0.6 | -0.5 | 0.6 | -0.5 | 0.3 | -0.4 | 0.5 | 0.5 | 0.1 | -0.1 | 0.1 | 0.4 | -0.6 | 0.0 | -0.1 | -0.6 | -0.1 | -0.1 | 0.4 | -0.5 | -0.6 | -0.4 | 0.4 | 0.6 | 0.0 | -0.5 | 0.4 | -0.1 | -0.4 | 0.2 | 0.1 | -0.0 | 0.5 | 0.4 | -0.1 |
Cocaine response before conditioning | 0.2 | 0.2 | 0.4 | -0.6 | 0.5 | -0.5 | 0.5 | 0.5 | -0.5 | -0.0 | 0.5 | -0.4 | -0.3 | -0.5 | 0.6 | -0.5 | 0.6 | 0.4 | -0.6 | 0.6 | 0.4 | -0.5 | 0.5 | -0.3 | -0.4 | 0.4 | -0.4 | 0.4 | -0.0 | 0.6 | -0.5 | -0.3 | -0.4 | 0.6 | -0.4 | -0.5 | 0.6 | 0.0 | -0.5 | 0.6 | -0.5 | -0.3 | -0.6 | 0.6 | 0.6 | 0.5 | -0.6 | -0.4 | -0.2 | 0.7 | -0.6 | 0.6 | 0.5 | -0.3 | 0.5 | 0.4 | -0.7 | -0.5 | -0.3 |
Conditioned reinforcement - actives | 0.2 | 0.2 | 0.4 | -0.4 | 0.5 | -0.5 | 0.5 | 0.3 | -0.5 | -0.0 | 0.5 | -0.5 | -0.3 | -0.4 | 0.5 | -0.3 | 0.4 | 0.1 | -0.7 | 0.4 | 0.2 | -0.4 | 0.5 | -0.4 | -0.3 | 0.4 | -0.3 | 0.4 | -0.1 | 0.4 | -0.4 | -0.2 | -0.6 | 0.4 | -0.6 | -0.2 | 0.5 | -0.3 | -0.5 | 0.5 | -0.5 | -0.4 | -0.5 | 0.4 | 0.4 | 0.2 | -0.4 | -0.2 | -0.3 | 0.5 | -0.5 | 0.3 | 0.3 | -0.4 | 0.5 | 0.4 | -0.5 | -0.2 | -0.4 |
Intermittent access total locomotion | 0.2 | 0.2 | 0.9 | -0.2 | 0.1 | -0.1 | 0.1 | 0.2 | -0.1 | -0.9 | 0.1 | 0.7 | 0.3 | -0.2 | 0.2 | -0.2 | 0.1 | 0.4 | 0.3 | 0.1 | 0.8 | 0.3 | 0.4 | 0.7 | -0.8 | 0.7 | -0.8 | 0.7 | -0.7 | 0.2 | -0.5 | -0.7 | 0.5 | -0.4 | 0.5 | -0.3 | 0.1 | 0.6 | -0.3 | 0.1 | -0.3 | 0.7 | -0.0 | 0.1 | 0.4 | 0.3 | -0.2 | -0.8 | -0.2 | 0.1 | -0.0 | 0.2 | 0.2 | 0.7 | -0.1 | -0.4 | -0.1 | -0.3 | 0.1 |
Short access day 1 locomotion | 0.2 | 0.2 | 1.3 | 0.1 | 0.0 | -0.0 | 0.0 | -0.3 | -0.0 | -0.8 | 0.0 | 0.8 | 0.7 | 0.2 | -0.0 | 0.4 | -0.1 | -0.2 | -0.1 | -0.1 | 0.6 | 0.6 | 0.4 | 0.8 | -0.6 | 0.6 | -0.5 | 0.7 | -0.6 | -0.1 | -0.4 | -1.1 | 0.1 | -0.9 | 0.0 | 0.4 | -0.1 | -0.5 | -0.3 | -0.1 | -0.3 | 0.8 | 0.1 | -0.1 | 0.3 | -0.4 | 0.1 | -0.6 | -0.1 | -0.0 | 0.1 | 0.1 | -0.3 | 0.8 | -0.4 | -0.8 | 0.0 | 0.4 | 0.4 |
Pavlov. Cond. intertrial magazine entries | 0.2 | 0.3 | 1.5 | -0.3 | 0.5 | -0.5 | 0.5 | 0.1 | -0.5 | 0.2 | 0.5 | -0.8 | -0.6 | -0.2 | 0.4 | -0.3 | 0.5 | -0.2 | -0.7 | 0.5 | -0.2 | -0.6 | 0.5 | -0.7 | -0.4 | 0.5 | -0.4 | 0.5 | -0.6 | 0.3 | -0.6 | 0.0 | -0.8 | 0.3 | -0.9 | -0.1 | 0.5 | -0.2 | -0.9 | 0.5 | -0.9 | -0.7 | -0.6 | 0.5 | 0.4 | 0.2 | -0.4 | 0.1 | -1.2 | 0.5 | -0.5 | 0.5 | 0.1 | -0.8 | 0.5 | 0.4 | -0.5 | -0.1 | -1.0 |
Bone: cortical porosity | 0.2 | 0.3 | 0.8 | -0.5 | 0.5 | -0.5 | 0.5 | 0.3 | -0.5 | 0.5 | 0.5 | -0.8 | -0.8 | -0.4 | 0.5 | -0.4 | 0.5 | 0.1 | -0.7 | 0.5 | -0.2 | -0.8 | 0.5 | -0.8 | 0.1 | 0.1 | 0.0 | 0.1 | 0.3 | 0.5 | -0.3 | 0.4 | -0.8 | 0.8 | -0.8 | -0.3 | 0.5 | -0.2 | -0.4 | 0.5 | -0.4 | -0.9 | -0.6 | 0.5 | 0.3 | 0.3 | -0.4 | 0.2 | -0.4 | 0.5 | -0.5 | 0.5 | 0.3 | -0.8 | 0.7 | 0.8 | -0.5 | -0.3 | -0.7 |
Distance traveled before self-admin | 0.2 | 0.2 | 0.7 | 0.1 | -0.1 | 0.1 | -0.1 | 0.5 | 0.1 | 0.2 | -0.1 | -0.2 | -0.2 | -0.2 | -0.3 | -0.4 | -0.1 | 0.6 | 0.7 | -0.1 | 0.0 | -0.1 | -0.6 | 0.2 | 0.6 | -0.5 | 0.3 | -0.5 | 0.5 | -0.0 | 0.6 | 0.6 | 0.7 | 0.5 | 0.7 | -0.7 | -0.1 | 0.9 | 0.6 | -0.1 | 0.6 | -0.0 | 0.1 | -0.1 | -0.3 | 0.6 | 0.1 | -0.1 | 0.6 | -0.1 | 0.2 | -0.3 | 0.5 | 0.1 | -0.1 | 0.4 | 0.1 | -0.7 | 0.1 |
Extinction: sum of active levers before priming | 0.2 | 0.2 | 1.6 | 0.1 | 0.1 | -0.1 | 0.1 | 0.6 | -0.1 | -0.6 | 0.1 | 0.4 | -0.3 | -0.3 | -0.1 | -0.5 | -0.1 | 0.8 | 0.8 | -0.1 | 0.2 | 0.1 | -0.2 | 0.5 | 0.1 | -0.2 | -0.1 | -0.2 | -0.2 | -0.2 | 0.2 | 0.2 | 0.9 | 0.4 | 1.0 | -1.0 | 0.1 | 1.3 | 0.2 | 0.1 | 0.2 | 0.6 | 0.0 | -0.1 | -0.1 | 0.8 | 0.2 | -0.3 | 0.1 | 0.0 | 0.3 | 0.0 | 0.6 | 0.4 | 0.0 | 0.1 | -0.0 | -1.0 | 0.0 |
Time in open arm after self-admin | 0.2 | 0.2 | 0.8 | -0.1 | 0.3 | -0.3 | 0.3 | 0.4 | -0.3 | 0.4 | 0.3 | -0.7 | -0.5 | -0.2 | 0.3 | -0.4 | 0.0 | 0.3 | -0.1 | 0.0 | -0.4 | -0.5 | -0.4 | -0.7 | 0.6 | -0.4 | 0.4 | -0.5 | 0.9 | 0.1 | 0.3 | 0.8 | -0.2 | 0.6 | -0.2 | -0.6 | 0.2 | 0.3 | 0.5 | 0.2 | 0.5 | -0.6 | -0.2 | 0.0 | -0.2 | 0.4 | -0.1 | 0.4 | 0.5 | 0.2 | -0.0 | -0.2 | 0.4 | -0.6 | 0.2 | 0.9 | -0.2 | -0.6 | -0.1 |
Delay disc. indifference point, 2s delay | 0.2 | 0.3 | 1.2 | -0.1 | 0.2 | -0.2 | 0.2 | 0.2 | -0.2 | 0.9 | 0.2 | -0.8 | -1.0 | -0.3 | 0.1 | -0.4 | 0.2 | 0.1 | -0.4 | 0.2 | -0.4 | -0.9 | -0.1 | -1.1 | 0.6 | -0.4 | 0.4 | -0.5 | 0.8 | 0.3 | 0.3 | 0.9 | -0.7 | 1.0 | -0.6 | -0.4 | 0.3 | 0.2 | 0.1 | 0.3 | 0.1 | -0.6 | -0.4 | 0.2 | -0.1 | 0.3 | -0.2 | 0.4 | -0.1 | 0.2 | -0.3 | 0.1 | 0.2 | -0.8 | 0.6 | 1.1 | -0.2 | -0.4 | -0.7 |
Fecal boli incidents, locomotor time 1 | 0.2 | 0.2 | 0.7 | 0.2 | -0.4 | 0.4 | -0.4 | -0.5 | 0.4 | 0.9 | -0.4 | -0.3 | -0.0 | 0.3 | -0.2 | 0.4 | -0.4 | -0.5 | 0.1 | -0.4 | -0.5 | 0.0 | -0.1 | -0.3 | 0.7 | -0.6 | 0.7 | -0.7 | 0.7 | -0.2 | 0.6 | 0.5 | -0.2 | 0.1 | -0.2 | 0.4 | -0.4 | -0.6 | 0.1 | -0.4 | 0.1 | -0.4 | 0.3 | -0.4 | -0.5 | -0.5 | 0.3 | 0.7 | 0.5 | -0.5 | 0.3 | -0.1 | -0.5 | -0.3 | 0.1 | -0.0 | 0.5 | 0.4 | 0.2 |
Progressive ratio | 0.2 | 0.2 | 1.2 | 0.0 | -0.0 | 0.0 | -0.0 | 0.1 | 0.0 | -1.1 | -0.0 | 1.0 | 0.5 | -0.1 | -0.0 | -0.0 | -0.2 | 0.3 | 0.5 | -0.2 | 0.9 | 0.7 | -0.0 | 0.7 | -0.6 | 0.3 | -0.6 | 0.4 | -0.9 | -0.0 | -0.3 | -0.6 | 0.8 | -0.7 | 0.8 | -0.1 | -0.1 | 0.6 | 0.0 | -0.1 | 0.0 | 1.1 | 0.2 | -0.2 | 0.1 | 0.1 | 0.1 | -0.8 | 0.1 | -0.1 | 0.3 | -0.1 | 0.1 | 0.6 | -0.4 | -0.6 | 0.1 | -0.1 | 0.5 |
K content in liver | 0.2 | 0.2 | 0.8 | 0.3 | -0.3 | 0.3 | -0.3 | -0.3 | 0.3 | -0.5 | -0.3 | 0.8 | 0.9 | 0.3 | -0.3 | 0.4 | -0.3 | -0.1 | 0.5 | -0.3 | 0.4 | 0.8 | -0.4 | 0.8 | -0.2 | 0.1 | -0.2 | 0.1 | -0.2 | -0.3 | 0.0 | -0.7 | 0.6 | -0.6 | 0.6 | 0.3 | -0.3 | -0.0 | 0.4 | -0.3 | 0.4 | 0.8 | 0.5 | -0.3 | -0.0 | -0.2 | 0.2 | -0.4 | 0.5 | -0.3 | 0.4 | -0.4 | -0.3 | 0.8 | -0.6 | -0.8 | 0.3 | 0.3 | 0.8 |
Length with tail | 0.1 | 0.4 | 1.3 | 0.7 | -0.5 | 0.5 | -0.5 | -0.3 | 0.5 | 0.1 | -0.5 | 0.5 | 0.4 | 0.5 | -0.8 | 0.4 | -0.6 | -0.1 | 0.8 | -0.6 | -0.4 | 0.5 | -0.9 | 0.4 | 0.7 | -0.8 | 0.6 | -0.7 | 0.7 | -0.7 | 0.8 | 0.4 | 0.7 | -0.4 | 0.7 | 0.1 | -0.6 | 0.2 | 1.1 | -0.6 | 1.1 | 0.4 | 0.6 | -0.6 | -0.6 | -0.2 | 0.7 | 0.3 | 1.0 | -0.6 | 0.8 | -0.8 | -0.3 | 0.4 | -0.6 | -0.2 | 0.6 | 0.1 | 0.8 |
Times rat made contact with spout | 0.1 | 0.1 | 0.6 | -0.2 | 0.1 | -0.1 | 0.1 | -0.1 | -0.1 | 0.4 | 0.1 | -0.2 | -0.5 | -0.2 | 0.5 | -0.1 | 0.1 | -0.1 | -0.3 | 0.1 | -0.1 | -0.4 | 0.5 | -0.4 | -0.1 | 0.2 | -0.0 | 0.2 | -0.4 | 0.2 | -0.2 | 0.1 | -0.4 | 0.2 | -0.5 | 0.1 | 0.1 | 0.1 | -0.6 | 0.1 | -0.6 | -0.4 | -0.3 | 0.1 | 0.0 | -0.1 | -0.2 | 0.2 | -0.8 | 0.1 | -0.3 | 0.5 | -0.1 | -0.2 | 0.5 | 0.2 | -0.1 | 0.1 | -0.7 |
Delay discounting water rate 24 sec | 0.1 | 0.1 | 0.5 | 0.3 | -0.2 | 0.2 | -0.2 | -0.2 | 0.2 | -0.3 | -0.2 | 0.4 | 0.5 | 0.4 | -0.5 | 0.3 | -0.2 | -0.2 | 0.3 | -0.2 | 0.0 | 0.5 | -0.6 | 0.4 | -0.2 | 0.1 | -0.2 | 0.2 | -0.4 | -0.3 | -0.0 | -0.3 | 0.3 | -0.5 | 0.3 | 0.3 | -0.3 | 0.0 | 0.3 | -0.3 | 0.3 | 0.5 | 0.3 | -0.2 | -0.0 | -0.2 | 0.4 | -0.2 | 0.1 | -0.1 | 0.2 | -0.6 | -0.2 | 0.4 | -0.7 | -0.5 | 0.1 | 0.3 | 0.3 |
Reaction time false alarm rate | 0.1 | 0.2 | 2.0 | -0.1 | 0.0 | -0.0 | 0.0 | -0.7 | -0.0 | 0.1 | 0.0 | -0.2 | 1.1 | 0.5 | -0.5 | 0.7 | -0.0 | -0.8 | -0.5 | -0.0 | 0.0 | 0.4 | -0.3 | -0.0 | -0.4 | 0.3 | -0.2 | 0.3 | 0.4 | 0.0 | -0.2 | -0.6 | -0.5 | -0.6 | -0.5 | 0.7 | -0.1 | -1.4 | 0.4 | -0.1 | 0.4 | 0.1 | 0.2 | -0.0 | 0.2 | -0.7 | -0.0 | 0.0 | 0.3 | 0.1 | -0.1 | -0.3 | -0.7 | -0.1 | -0.6 | -0.7 | -0.1 | 0.7 | 0.6 |
Pavlov. Cond. magazine entry number | 0.1 | 0.1 | 0.5 | 0.0 | 0.0 | -0.0 | 0.0 | -0.1 | -0.0 | -0.2 | 0.0 | 0.6 | 0.5 | 0.1 | -0.0 | 0.1 | 0.0 | 0.0 | 0.1 | 0.0 | 0.4 | 0.4 | -0.0 | 0.5 | -0.5 | 0.4 | -0.4 | 0.4 | -0.4 | -0.0 | -0.3 | -0.7 | 0.3 | -0.4 | 0.3 | 0.1 | 0.0 | 0.2 | -0.1 | 0.0 | 0.0 | 0.5 | 0.1 | 0.0 | 0.2 | -0.0 | -0.0 | -0.5 | -0.1 | -0.0 | -0.0 | -0.1 | -0.1 | 0.6 | -0.4 | -0.5 | 0.0 | 0.1 | 0.3 |
Pavlov. Cond. intertrial magazine entries | 0.1 | 0.2 | 1.0 | 0.0 | 0.0 | -0.0 | 0.0 | -0.2 | -0.0 | 1.0 | 0.0 | -0.5 | -0.4 | 0.2 | -0.0 | 0.1 | 0.0 | -0.5 | -0.5 | 0.0 | -0.7 | -0.5 | 0.1 | -0.9 | 0.5 | -0.4 | 0.5 | -0.4 | 0.8 | 0.0 | 0.2 | 0.5 | -0.7 | 0.5 | -0.7 | 0.2 | 0.1 | -0.4 | 0.1 | 0.1 | 0.0 | -0.9 | -0.1 | 0.0 | -0.2 | -0.2 | 0.0 | 0.6 | 0.2 | 0.0 | -0.1 | -0.0 | -0.2 | -0.6 | 0.3 | 0.5 | -0.0 | 0.2 | -0.2 |
Intermitt. access escalation Index | 0.1 | 0.1 | 0.5 | -0.4 | 0.4 | -0.4 | 0.4 | 0.2 | -0.4 | 0.4 | 0.4 | -0.6 | -0.3 | -0.3 | 0.4 | -0.1 | 0.4 | -0.0 | -0.7 | 0.4 | -0.0 | -0.5 | 0.1 | -0.5 | -0.0 | 0.2 | -0.0 | 0.2 | 0.1 | 0.4 | -0.2 | -0.0 | -0.7 | 0.5 | -0.7 | 0.0 | 0.3 | -0.5 | -0.2 | 0.3 | -0.2 | -0.5 | -0.4 | 0.4 | 0.3 | -0.0 | -0.4 | 0.1 | -0.3 | 0.2 | -0.4 | 0.4 | 0.2 | -0.5 | 0.5 | 0.4 | -0.2 | 0.0 | -0.4 |
Intermittent access day 1 locomotion | 0.1 | 0.1 | 0.3 | -0.3 | 0.5 | -0.5 | 0.5 | 0.3 | -0.5 | -0.5 | 0.5 | 0.1 | -0.1 | -0.3 | 0.2 | -0.4 | 0.3 | 0.3 | -0.1 | 0.3 | 0.4 | -0.1 | 0.4 | 0.1 | -0.5 | 0.5 | -0.5 | 0.5 | -0.4 | 0.3 | -0.3 | -0.3 | 0.1 | 0.2 | 0.0 | -0.6 | 0.3 | 0.4 | -0.3 | 0.3 | -0.3 | 0.1 | -0.3 | 0.3 | 0.4 | 0.4 | -0.3 | -0.4 | -0.4 | 0.3 | -0.3 | 0.1 | 0.3 | 0.1 | 0.1 | 0.1 | -0.3 | -0.6 | -0.2 |
Baseline Anxiety | 0.1 | 0.1 | 0.4 | -0.3 | 0.3 | -0.3 | 0.3 | 0.4 | -0.3 | 0.2 | 0.3 | -0.3 | -0.4 | -0.4 | 0.4 | -0.4 | 0.3 | 0.3 | -0.3 | 0.3 | 0.0 | -0.4 | 0.2 | -0.4 | -0.1 | 0.1 | -0.1 | 0.1 | 0.1 | 0.3 | -0.2 | 0.1 | -0.3 | 0.6 | -0.3 | -0.5 | 0.3 | 0.1 | -0.2 | 0.3 | -0.2 | -0.4 | -0.4 | 0.3 | 0.2 | 0.4 | -0.3 | -0.0 | -0.2 | 0.3 | -0.3 | 0.5 | 0.4 | -0.4 | 0.6 | 0.5 | -0.3 | -0.5 | -0.3 |
Stereotopy head waving bouts, day 3 | 0.1 | 0.1 | 0.6 | -0.0 | -0.1 | 0.1 | -0.1 | 0.1 | 0.1 | 0.7 | -0.1 | -0.8 | -0.7 | -0.1 | 0.2 | -0.1 | -0.1 | -0.2 | -0.2 | -0.1 | -0.5 | -0.5 | 0.3 | -0.7 | 0.6 | -0.5 | 0.6 | -0.5 | 0.2 | 0.1 | 0.2 | 0.7 | -0.5 | 0.6 | -0.5 | 0.1 | -0.1 | -0.2 | -0.3 | -0.1 | -0.3 | -0.7 | -0.2 | -0.1 | -0.3 | -0.1 | 0.0 | 0.6 | -0.3 | -0.1 | -0.1 | 0.2 | 0.1 | -0.7 | 0.5 | 0.5 | 0.1 | 0.1 | -0.6 |
Pavlov. Cond. lever latency | 0.1 | 0.2 | 1.0 | 0.0 | 0.1 | -0.1 | 0.1 | -0.3 | -0.1 | -0.7 | 0.1 | 0.7 | 0.7 | 0.2 | 0.1 | 0.2 | 0.1 | -0.2 | -0.0 | 0.1 | 0.4 | 0.5 | 0.3 | 0.5 | -0.9 | 0.8 | -0.7 | 0.8 | -0.9 | -0.0 | -0.6 | -0.8 | 0.1 | -1.0 | 0.1 | 0.3 | -0.0 | 0.1 | -0.4 | -0.0 | -0.4 | 0.5 | 0.1 | 0.1 | 0.4 | -0.2 | -0.1 | -0.5 | -0.4 | 0.1 | -0.0 | 0.3 | -0.3 | 0.7 | -0.2 | -0.7 | -0.1 | 0.3 | 0.2 |
Pavlov. Cond. index score | 0.1 | 0.1 | 0.6 | -0.2 | -0.0 | 0.0 | -0.0 | 0.3 | 0.0 | 0.6 | -0.0 | -0.4 | -0.5 | -0.3 | 0.1 | -0.2 | 0.0 | 0.2 | -0.1 | 0.0 | -0.1 | -0.4 | -0.2 | -0.5 | 0.6 | -0.5 | 0.5 | -0.6 | 0.7 | 0.2 | 0.4 | 0.6 | -0.2 | 0.8 | -0.1 | -0.3 | 0.1 | 0.1 | 0.2 | 0.1 | 0.2 | -0.5 | -0.1 | 0.0 | -0.2 | 0.2 | -0.0 | 0.4 | 0.3 | 0.0 | -0.1 | -0.1 | 0.3 | -0.5 | 0.3 | 0.6 | -0.0 | -0.3 | -0.2 |
Pavlov. Cond. latency score | 0.1 | 0.1 | 0.5 | -0.0 | -0.2 | 0.2 | -0.2 | 0.2 | 0.2 | 0.4 | -0.2 | -0.1 | -0.4 | -0.2 | -0.1 | -0.2 | -0.2 | 0.3 | 0.2 | -0.2 | -0.0 | -0.2 | -0.4 | -0.2 | 0.7 | -0.7 | 0.6 | -0.7 | 0.7 | 0.0 | 0.6 | 0.6 | 0.2 | 0.6 | 0.2 | -0.3 | -0.1 | 0.2 | 0.4 | -0.1 | 0.4 | -0.2 | 0.1 | -0.2 | -0.3 | 0.2 | 0.1 | 0.3 | 0.5 | -0.2 | 0.1 | -0.3 | 0.2 | -0.2 | 0.0 | 0.4 | 0.2 | -0.3 | 0.1 |
Pavlov. Cond. magazine entry number | 0.1 | 0.1 | 0.6 | 0.4 | -0.3 | 0.3 | -0.3 | -0.4 | 0.3 | -0.3 | -0.3 | 0.2 | 0.5 | 0.5 | -0.4 | 0.4 | -0.3 | -0.4 | 0.3 | -0.3 | -0.2 | 0.5 | -0.2 | 0.5 | -0.1 | 0.1 | -0.1 | 0.1 | -0.2 | -0.4 | 0.1 | -0.2 | 0.3 | -0.7 | 0.3 | 0.4 | -0.3 | -0.2 | 0.2 | -0.3 | 0.2 | 0.5 | 0.4 | -0.3 | -0.2 | -0.4 | 0.3 | -0.1 | 0.1 | -0.3 | 0.4 | -0.3 | -0.4 | 0.4 | -0.4 | -0.6 | 0.3 | 0.4 | 0.3 |
Pavlov. Cond. lever-magazine prob. diff. | 0.1 | 0.1 | 1.0 | -0.3 | 0.1 | -0.1 | 0.1 | 0.3 | -0.1 | 0.7 | 0.1 | -0.6 | -0.6 | -0.4 | 0.2 | -0.3 | 0.1 | 0.2 | -0.3 | 0.1 | -0.1 | -0.6 | 0.0 | -0.7 | 0.5 | -0.4 | 0.4 | -0.4 | 0.7 | 0.3 | 0.3 | 0.5 | -0.4 | 1.0 | -0.4 | -0.3 | 0.2 | -0.0 | 0.0 | 0.2 | 0.1 | -0.7 | -0.3 | 0.1 | -0.1 | 0.2 | -0.2 | 0.4 | 0.1 | 0.1 | -0.3 | 0.1 | 0.3 | -0.7 | 0.4 | 0.7 | -0.1 | -0.3 | -0.3 |
Bone: cortical porosity | 0.1 | 0.2 | 0.7 | -0.1 | 0.1 | -0.1 | 0.1 | -0.0 | -0.1 | 0.7 | 0.1 | -0.8 | -0.6 | -0.1 | 0.2 | -0.1 | 0.1 | -0.2 | -0.5 | 0.1 | -0.5 | -0.6 | 0.2 | -0.8 | 0.4 | -0.3 | 0.4 | -0.3 | 0.6 | 0.1 | 0.1 | 0.6 | -0.7 | 0.7 | -0.6 | -0.0 | 0.2 | -0.5 | -0.1 | 0.2 | -0.1 | -0.8 | -0.2 | 0.1 | -0.1 | -0.1 | -0.1 | 0.5 | -0.0 | 0.1 | -0.2 | 0.2 | -0.0 | -0.8 | 0.5 | 0.7 | -0.1 | -0.0 | -0.4 |
Delta time in closed arm before/after self-admin | 0.1 | 0.1 | 0.2 | 0.2 | -0.2 | 0.2 | -0.2 | -0.1 | 0.2 | -0.4 | -0.2 | 0.2 | 0.0 | 0.1 | -0.2 | 0.1 | -0.3 | 0.1 | 0.4 | -0.3 | 0.0 | 0.3 | 0.1 | 0.4 | -0.1 | -0.0 | -0.0 | 0.0 | -0.4 | -0.3 | 0.0 | -0.0 | 0.5 | -0.2 | 0.5 | -0.1 | -0.2 | 0.2 | -0.1 | -0.2 | -0.2 | 0.5 | 0.2 | -0.3 | -0.2 | -0.0 | 0.3 | -0.1 | -0.1 | -0.2 | 0.3 | 0.1 | -0.1 | 0.3 | -0.1 | -0.3 | 0.2 | -0.1 | 0.0 |
Delta time in open arm before/after self-admin | 0.1 | 0.1 | 0.4 | 0.3 | -0.1 | 0.1 | -0.1 | -0.1 | 0.1 | -0.3 | -0.1 | 0.5 | 0.4 | 0.4 | -0.3 | 0.2 | -0.3 | -0.1 | 0.2 | -0.3 | 0.0 | 0.4 | -0.5 | 0.1 | 0.1 | -0.2 | 0.1 | -0.2 | 0.3 | -0.3 | 0.2 | -0.0 | 0.3 | -0.4 | 0.3 | 0.1 | -0.1 | 0.1 | 0.6 | -0.1 | 0.6 | 0.3 | 0.3 | -0.3 | -0.2 | -0.1 | 0.3 | -0.0 | 0.6 | -0.1 | 0.3 | -0.5 | -0.1 | 0.3 | -0.4 | -0.1 | 0.1 | 0.1 | 0.6 |
Time in closed arm before self-admin | 0.1 | 0.1 | 0.5 | -0.3 | 0.0 | -0.0 | 0.0 | -0.3 | -0.0 | 0.4 | 0.0 | -0.2 | 0.1 | -0.1 | 0.3 | 0.1 | 0.4 | -0.4 | -0.6 | 0.4 | 0.0 | -0.2 | 0.5 | -0.1 | -0.4 | 0.4 | -0.2 | 0.4 | -0.4 | 0.4 | -0.4 | -0.5 | -0.6 | 0.0 | -0.7 | 0.5 | 0.1 | -0.6 | -0.6 | 0.1 | -0.6 | -0.3 | -0.2 | 0.4 | 0.3 | -0.4 | -0.4 | -0.0 | -0.7 | 0.1 | -0.4 | 0.3 | -0.3 | -0.1 | 0.2 | -0.2 | -0.1 | 0.5 | -0.4 |
Sum of active levers in priming session hrs 5-6 | 0.1 | 0.1 | 0.3 | -0.4 | 0.4 | -0.4 | 0.4 | 0.3 | -0.4 | 0.0 | 0.4 | -0.0 | 0.2 | -0.2 | 0.4 | -0.2 | 0.4 | 0.2 | -0.5 | 0.4 | 0.3 | -0.1 | 0.1 | 0.0 | -0.4 | 0.5 | -0.4 | 0.5 | -0.0 | 0.3 | -0.3 | -0.6 | -0.3 | 0.4 | -0.3 | -0.2 | 0.5 | -0.2 | 0.0 | 0.5 | 0.0 | 0.1 | -0.3 | 0.4 | 0.5 | 0.2 | -0.4 | -0.4 | -0.1 | 0.4 | -0.4 | 0.1 | 0.3 | 0.0 | 0.0 | -0.0 | -0.4 | -0.2 | 0.1 |
Time to tail flick, test, after self-admin | 0.1 | 0.1 | 0.6 | 0.3 | -0.4 | 0.4 | -0.4 | -0.4 | 0.4 | -0.3 | -0.4 | 0.4 | 0.5 | 0.3 | -0.3 | 0.4 | -0.3 | -0.3 | 0.4 | -0.3 | 0.1 | 0.5 | -0.0 | 0.6 | -0.0 | 0.1 | -0.0 | 0.1 | -0.8 | -0.2 | -0.1 | -0.3 | 0.4 | -0.6 | 0.3 | 0.4 | -0.3 | -0.1 | -0.0 | -0.3 | -0.1 | 0.4 | 0.3 | -0.3 | -0.1 | -0.3 | 0.3 | -0.1 | -0.2 | -0.4 | 0.3 | -0.1 | -0.4 | 0.5 | -0.3 | -0.6 | 0.4 | 0.4 | 0.1 |
Mg content in liver | 0.1 | 0.2 | 0.7 | -0.3 | 0.3 | -0.3 | 0.3 | 0.6 | -0.3 | -0.6 | 0.3 | 0.4 | -0.1 | -0.5 | 0.3 | -0.5 | 0.3 | 0.8 | 0.2 | 0.3 | 0.7 | -0.0 | 0.2 | 0.4 | -0.3 | 0.3 | -0.4 | 0.3 | -0.4 | 0.3 | -0.2 | -0.4 | 0.5 | 0.2 | 0.5 | -0.6 | 0.3 | 0.9 | -0.1 | 0.3 | -0.1 | 0.4 | -0.2 | 0.3 | 0.3 | 0.6 | -0.3 | -0.7 | -0.0 | 0.3 | -0.2 | 0.3 | 0.6 | 0.5 | 0.2 | 0.1 | -0.3 | -0.6 | 0.0 |
Se content in liver | 0.1 | 0.1 | 0.2 | -0.3 | 0.4 | -0.4 | 0.4 | 0.0 | -0.4 | 0.1 | 0.4 | -0.1 | 0.2 | 0.0 | 0.0 | -0.0 | 0.3 | -0.1 | -0.5 | 0.3 | 0.2 | -0.1 | -0.0 | -0.2 | -0.3 | 0.4 | -0.3 | 0.3 | 0.0 | 0.3 | -0.4 | -0.3 | -0.4 | 0.2 | -0.4 | -0.0 | 0.3 | -0.4 | 0.0 | 0.3 | 0.0 | -0.1 | -0.2 | 0.3 | 0.4 | 0.0 | -0.3 | -0.2 | -0.1 | 0.4 | -0.3 | -0.0 | 0.0 | -0.2 | -0.1 | 0.0 | -0.4 | -0.0 | 0.0 |
Pavlov. Cond. magazine entry latency | 0.0 | 0.0 | 0.1 | 0.1 | -0.2 | 0.2 | -0.2 | 0.0 | 0.2 | -0.1 | -0.2 | -0.0 | -0.1 | 0.0 | -0.2 | 0.0 | -0.2 | 0.0 | 0.3 | -0.2 | -0.1 | 0.0 | -0.2 | 0.1 | 0.3 | -0.3 | 0.3 | -0.3 | 0.2 | -0.1 | 0.3 | 0.4 | 0.2 | -0.1 | 0.2 | 0.0 | -0.2 | 0.1 | 0.4 | -0.2 | 0.3 | 0.1 | 0.2 | -0.2 | -0.3 | -0.1 | 0.2 | 0.2 | 0.2 | -0.2 | 0.2 | -0.2 | 0.0 | -0.0 | -0.1 | 0.1 | 0.2 | 0.0 | 0.1 |
Time in novel zone, hab. session 1 | 0.0 | 0.0 | 0.1 | -0.1 | 0.2 | -0.2 | 0.2 | 0.2 | -0.2 | -0.2 | 0.2 | -0.1 | 0.1 | -0.0 | 0.1 | -0.1 | 0.2 | 0.1 | -0.2 | 0.2 | 0.0 | -0.1 | 0.1 | -0.0 | -0.2 | 0.2 | -0.3 | 0.2 | 0.1 | 0.1 | -0.2 | -0.2 | -0.1 | 0.0 | -0.1 | -0.2 | 0.2 | -0.2 | 0.1 | 0.2 | 0.1 | 0.0 | -0.1 | 0.2 | 0.3 | 0.2 | -0.2 | -0.2 | 0.1 | 0.2 | -0.1 | -0.0 | 0.2 | -0.2 | -0.0 | 0.0 | -0.2 | -0.2 | 0.1 |
Delta time to tail flick, test, before/after SA | 0.0 | 0.0 | 0.2 | 0.0 | -0.0 | 0.0 | -0.0 | -0.1 | 0.0 | 0.0 | -0.0 | -0.2 | -0.1 | -0.0 | 0.0 | 0.0 | -0.1 | -0.1 | -0.0 | -0.1 | -0.1 | -0.0 | 0.2 | -0.0 | 0.0 | 0.0 | 0.1 | 0.0 | -0.3 | -0.0 | -0.1 | 0.0 | -0.1 | -0.1 | -0.1 | 0.1 | -0.1 | -0.1 | -0.3 | -0.1 | -0.4 | -0.1 | -0.0 | -0.1 | -0.1 | -0.2 | 0.0 | 0.2 | -0.3 | -0.0 | -0.0 | 0.4 | -0.1 | -0.1 | 0.2 | -0.1 | 0.0 | 0.1 | -0.2 |
For each tested trait, stats based on TWAS chi2 (squared Z-score) for the above models are shown. Avg chi2 ratio is the mean chi2 across all models for this gene, divided by the mean chi2 across all models for all genes. Avg chi2 is the mean chi2 across all models for this gene. Max chi2 is the highest chi2 across all models for this gene.
The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.