Tpp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio ENSRNOT00000015393 0.02 0.02 9.9e-03 0.03 0.01 0.01 0.01 1.1e-03 2.4e-02 6.3e-02 3.9e-02
2 Brain isoform ratio ENSRNOT00000078220 0.03 0.03 5.7e-03 0.01 0.01 0.02 0.01 1.5e-02 3.1e-02 1.1e-02 2.5e-02
3 Eye isoform ratio ENSRNOT00000078220 0.29 0.19 5.8e-03 0.04 0.01 -0.02 0 7.8e-02 2.3e-01 9.2e-01 2.9e-01
4 Eye intron excision ratio chr9:46107749:46109521 0.68 0.18 1.0e-03 -0.01 -0.02 -0.02 -0.02 4.0e-01 8.1e-01 9.6e-01 6.7e-01
5 Eye intron excision ratio chr9:46107749:46114443 0.46 0.23 6.1e-03 -0.02 -0.02 -0 -0.02 8.6e-01 8.4e-01 3.3e-01 6.8e-01
6 NAcc intron excision ratio chr9:46107749:46109521 0.03 0.03 7.5e-03 0.01 0.02 0.02 -0 3.5e-02 2.0e-02 2.1e-02 4.8e-01
7 NAcc intron excision ratio chr9:46107749:46114443 0.03 0.02 7.4e-03 0.02 0.03 0.02 0 9.9e-03 5.7e-03 1.1e-02 1.7e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail2.89.110.4-3.22.93.0-2.53.1-3.23.1
BMI without tail0.00.10.20.2-0.3-0.30.3-0.40.4-0.2
Body weight0.20.71.0-0.81.00.7-0.90.9-0.80.7
Epididymis fat weight0.00.10.40.2-0.7-0.2-0.10.00.00.0
Glucose0.10.10.40.3-0.2-0.00.6-0.50.4-0.2
Heart weight0.20.30.6-0.6-0.30.5-0.10.4-0.70.8
Left kidney weight0.10.20.90.4-1.0-0.4-0.40.00.2-0.3
Right kidney weight0.20.73.80.20.3-0.3-2.00.9-0.2-0.3
Tail length1.54.56.12.0-1.7-2.02.3-2.52.3-2.0
Length with tail0.31.21.61.2-0.8-1.10.8-1.11.2-1.3
Length without tail1.73.75.1-1.71.91.7-2.22.3-2.01.6
Liver weight, left0.30.51.50.7-1.2-0.9-0.2-0.30.5-0.6
Liver weight, right0.20.30.40.6-0.5-0.60.3-0.50.6-0.6
Parametrial fat weight0.10.10.3-0.50.20.3-0.00.3-0.40.4
Retroperitoneal fat weight0.61.84.7-0.91.10.8-2.21.7-1.31.0
Intraocular pressure2.02.83.8-2.01.81.8-0.71.5-1.81.8
Extensor digitorum longus weight7.028.135.3-5.14.75.1-5.55.9-5.65.1
Soleus weight0.92.64.6-1.50.71.3-2.22.0-1.81.5
Tibialis anterior weight2.58.611.6-2.72.42.7-3.43.4-3.02.7
Tibia length0.10.30.40.6-0.5-0.60.1-0.40.5-0.6
Number of licking bursts0.60.71.20.8-1.1-0.90.8-1.00.8-0.6
Food consumed during 24 hour testing period0.81.01.3-1.01.11.0-0.70.9-1.01.1
Times rat made contact with spout1.01.22.70.7-0.9-0.81.6-1.41.1-0.6
Mean time between licks in bursts1.21.73.1-1.20.71.1-1.81.6-1.41.2
Mean num. licks in bursts0.30.40.7-0.80.70.80.00.5-0.60.6
Std. dev. time between licks in bursts0.60.71.3-0.80.40.8-1.10.9-0.80.9
Water consumed over 24 hours0.20.20.3-0.50.60.60.20.2-0.40.6
Indifference point 0 sec0.40.62.2-0.30.00.1-1.51.1-0.70.3
Indifference point AUC0.91.01.7-1.20.90.9-0.60.9-1.21.3
Indifference point function ln k0.20.30.7-0.6-0.20.90.30.4-0.50.5
Indifference point function log k0.20.30.7-0.6-0.20.90.30.4-0.50.5
Delay discounting total patch changes 0 sec0.50.82.3-0.70.30.4-1.51.2-1.00.7
Delay discounting total patch changes 12 sec0.10.20.80.2-0.0-0.4-0.90.4-0.3-0.0
Delay discounting total patch changes 18 sec1.11.52.1-1.20.81.1-1.11.3-1.41.4
Delay discounting total patch changes 24 sec0.60.83.2-0.10.40.1-1.81.2-0.80.4
Delay discounting total patch changes 6 sec0.20.31.40.1-0.3-0.4-1.20.6-0.3-0.0
Delay discounting time to switch 0 sec0.61.01.51.2-0.9-1.00.5-0.91.1-1.2
Delay discounting water rate 0 sec0.60.91.6-1.30.81.1-0.10.6-1.01.2
Delay discounting water rate 12 sec0.10.10.1-0.4-0.30.4-0.00.2-0.20.3
Delay discounting water rate 18 sec0.60.81.70.9-1.3-0.90.5-0.80.8-0.8
Delay discounting water rate 24 sec0.00.00.1-0.1-0.20.10.00.0-0.00.0
Delay discounting water rate 6 sec0.10.20.6-0.2-0.70.30.6-0.20.00.2
Locomotor activity0.10.20.30.5-0.4-0.20.2-0.40.6-0.5
Locomotor testing distance1.32.12.51.5-1.6-1.31.1-1.41.6-1.6
Locomotor testing rearing1.82.83.91.8-1.2-1.81.2-1.71.9-2.0
Light reinforcement 14.88.710.6-2.83.12.6-3.13.3-3.12.7
Light reinforcement 21.72.32.9-1.41.31.3-1.71.7-1.61.5
Reaction time number correct1.01.41.8-1.20.81.3-0.91.3-1.31.2
Reaction time mean minus median1.62.12.81.4-1.2-1.51.2-1.61.7-1.5
Reaction time mean minus median AUC1.72.22.91.5-1.2-1.61.3-1.71.7-1.5
Reaction time num false alarms1.72.33.0-1.51.51.5-1.21.6-1.71.6
Reaction time num false alarms AUC2.43.44.4-1.81.71.7-1.72.0-2.11.9
Reaction time trials correct on left1.01.41.8-1.20.81.3-0.91.3-1.31.2
Reaction time trials on left0.91.31.7-1.20.81.3-0.91.3-1.31.1
Reaction time mean2.83.84.72.0-1.7-2.01.7-2.22.1-1.9
Reaction time mean AUC2.12.83.61.7-1.4-1.71.5-1.91.8-1.5
Median of all reaction times2.22.93.71.8-1.5-1.81.6-1.91.9-1.6
Reaction time omissions1.11.52.11.2-0.9-1.11.3-1.51.4-1.2
Reaction time false alarm rate0.71.01.3-0.91.00.8-1.11.1-1.11.0
Reaction time premature initiation rate0.00.10.10.3-0.1-0.30.0-0.20.3-0.3
Reaction time premature initiations0.10.20.2-0.30.40.4-0.40.5-0.40.3
Std. dev. reaction times3.14.35.22.0-2.0-2.11.8-2.32.2-2.0
Reaction time trials completed0.91.31.7-1.20.81.3-0.91.3-1.31.1
Reaction time trials AUC0.91.21.6-1.10.81.2-0.81.2-1.31.1
Social response proportion0.20.20.60.40.0-0.40.8-0.60.4-0.3
Social responses1.01.32.51.0-0.5-1.01.6-1.41.2-1.0
Social time4.15.36.62.3-1.9-2.32.1-2.52.6-2.4
Conditioned locomotion0.20.20.90.10.3-0.11.0-0.70.4-0.1
Cocaine response after cond. corrected0.60.71.3-1.10.91.00.40.3-0.71.1
Cocaine response after cond. not corrected0.60.61.0-1.01.00.9-0.00.4-0.71.0
Cocaine response before conditioning0.20.21.10.30.2-0.1-1.00.5-0.1-0.2
Saline control response0.30.40.9-0.40.90.3-0.80.7-0.70.4
Condit. Reinf. active minus inactive responses0.91.23.60.7-0.6-0.71.9-1.40.9-0.7
Condit. Reinf. active-inactive response ratio1.61.72.71.2-0.8-1.11.7-1.61.4-1.2
Condit. Reinf. active responses0.20.21.2-0.30.10.21.1-0.4-0.00.3
Condit. Reinf. inactive responses0.70.81.2-1.10.60.8-0.71.0-1.11.0
Condit. Reinf. lever presses0.60.81.20.8-0.8-1.01.1-1.00.8-0.7
Condit. Reinf. lever reinforcers received0.20.21.0-0.40.20.31.0-0.3-0.20.4
Pavlov. Cond. lever latency0.81.11.4-1.11.21.1-0.91.0-0.91.0
Pavlov. Cond. magazine entry latency0.50.51.11.0-0.2-1.0-0.6-0.10.6-1.0
Pavlov. Cond. change in total contacts1.01.42.50.9-1.3-1.11.6-1.31.0-0.9
Pavlov. Cond. index score0.50.71.01.0-0.8-1.00.6-0.70.8-0.9
Pavlov. Cond. latency score0.40.50.60.8-0.7-0.80.5-0.60.6-0.8
Pavlov. Cond. lever contacts1.92.63.51.7-1.9-1.81.3-1.51.5-1.6
Pavlov. Cond. magazine entry number1.01.22.1-1.40.81.40.10.7-1.11.4
Pavlov. Cond. intertrial magazine entries3.64.65.8-2.42.22.3-1.42.0-2.22.4
Pavlov. Cond. lever-magazine prob. diff.0.30.40.70.8-0.6-0.90.3-0.50.6-0.8
Pavlov. Cond. response bias1.92.74.11.9-1.8-2.00.5-1.21.6-1.9
Conditioned reinforcement - actives0.10.10.20.10.1-0.30.1-0.40.4-0.3
Conditioned reinforcement - inactives0.10.20.30.40.4-0.4-0.2-0.20.5-0.6
Conditioned locomotion2.42.95.5-1.52.11.3-2.31.9-1.41.2
Intermittent access intake day 1-15 change0.40.40.60.6-0.4-0.70.6-0.80.7-0.7
Intermittent access intake escalation1.00.91.30.9-0.5-1.01.0-1.11.1-1.0
Intermittent access intake escalation 21.81.72.21.3-1.1-1.31.3-1.51.4-1.3
Intermitt. access day 1 inactive lever presses0.10.10.30.10.6-0.2-0.60.10.2-0.3
Intermitt. access day 15 inactive lever presses0.30.30.70.7-0.4-0.7-0.5-0.10.6-0.8
Intermitt. access escalation Index0.10.10.40.20.3-0.2-0.60.2-0.0-0.0
Intermittent access day 1 total infusions0.20.21.2-0.2-0.00.11.1-0.60.20.2
Intermittent access day 15 total infusions0.91.01.80.7-0.5-0.91.3-1.31.2-0.8
Intermittent access terminal intake (last 3 days)0.40.41.00.4-0.4-0.41.0-0.90.7-0.3
Intermittent access total infusions0.50.51.50.3-0.4-0.41.2-1.00.7-0.3
Intermittent access day 1 locomotion0.10.10.1-0.30.40.2-0.20.2-0.20.2
Intermittent access day 15 total locomotion0.00.00.1-0.10.30.1-0.1-0.00.00.1
Intermittent access total locomotion0.00.10.2-0.30.40.2-0.10.1-0.10.2
Intermittent access standard deviation0.70.71.20.7-0.3-0.71.0-1.11.0-0.8
Cocaine induced anxiety2.32.64.9-1.31.51.3-2.22.0-1.61.2
Post-drug Anxiety2.62.93.6-1.71.91.7-1.31.7-1.81.7
Baseline Anxiety0.60.62.90.1-0.2-0.11.7-1.00.40.1
Lifetime Intake0.10.10.5-0.10.1-0.00.7-0.50.30.0
Incentive Sensitization - Responses0.60.61.10.8-0.4-0.90.3-0.80.9-1.0
Incentive Sensitization - Breakpoint0.40.40.90.7-0.3-0.80.2-0.60.8-0.9
Progressive ratio test 1 active lever presses0.40.40.6-0.70.70.6-0.30.5-0.60.7
Progressive ratio test 1 breakpoint0.40.40.6-0.80.70.6-0.40.6-0.70.8
Progressive ratio test 1 inactive lever presses0.20.31.20.30.4-0.4-1.10.30.1-0.4
Progressive ratio test 2 active lever presses0.10.20.30.2-0.0-0.40.3-0.50.6-0.5
Progressive ratio test 2 breakpoint0.00.00.1-0.10.3-0.00.1-0.20.2-0.1
Progressive ratio test 2 inactive lever presses0.30.40.90.7-0.0-0.7-0.2-0.40.7-0.9
Total sessions with >9 infusions1.92.12.5-1.61.61.5-1.11.4-1.41.5
Short access day 1 total inactive lever presses0.40.41.80.40.0-0.6-1.30.40.3-0.7
Short access day 10 total inactive lever presses0.30.30.70.70.1-0.6-0.3-0.20.6-0.8
Short access day 1 total infusions0.20.20.6-0.40.50.3-0.80.5-0.30.2
Short access day 10 total infusions0.20.31.3-0.2-0.10.11.1-0.60.20.3
Short access total infusions0.50.50.9-0.90.90.8-0.20.5-0.60.8
Short access day 1 locomotion0.40.40.9-0.50.60.5-1.00.8-0.50.5
Short access day 10 total locomotion0.10.10.20.4-0.4-0.40.1-0.30.4-0.4
Short access total locomotion1.01.12.4-0.81.10.7-1.61.2-0.80.7
Compulsive drug intake1.51.41.91.3-1.4-1.30.7-1.01.3-1.3
One hour access (0.3 mA shock)1.51.75.50.6-0.7-0.72.3-1.81.3-0.6
One hour access (shock baseline)0.40.41.90.00.2-0.11.4-0.90.50.0
Number of responses in last shaping day0.20.20.40.5-0.0-0.5-0.3-0.20.5-0.6
Context. condit. distance diff. score0.70.91.61.3-0.1-1.20.1-0.81.1-1.2
Locomotion velocity, session 10.00.00.1-0.10.40.20.3-0.1-0.10.1
Locomotion distance, session 11.21.52.1-1.11.41.3-0.91.3-1.31.0
Locomotion velocity, session 23.84.45.1-2.21.92.0-2.02.2-2.32.1
Locomotion distance, session 23.04.35.5-2.31.72.3-1.32.1-2.32.3
Locomotion velocity, session 30.10.10.20.5-0.1-0.4-0.1-0.20.4-0.5
Locomotion distance, session 30.10.10.10.3-0.2-0.30.3-0.30.3-0.3
Stereotopy head waving bouts, day 30.20.20.40.6-0.2-0.5-0.1-0.30.7-0.6
Stereotopy head waving duration, day 30.10.10.20.3-0.0-0.20.2-0.30.5-0.4
Locomotion velocity, session 71.01.13.8-0.50.70.5-2.01.4-0.90.5
Locomotion distance, session 70.81.01.3-1.00.90.9-1.11.1-1.11.0
Stereotopy head waving bouts, day 70.00.00.10.30.2-0.1-0.1-0.10.3-0.3
Stereotopy head waving duration, day 70.10.10.30.40.2-0.3-0.3-0.00.4-0.5
Locomotion velocity, session 80.00.10.2-0.10.20.1-0.40.4-0.2-0.1
Locomotion distance, session 80.91.31.8-0.91.31.0-1.31.3-1.10.8
Degree of sensitization distance1.51.51.7-1.31.11.2-1.11.2-1.31.3
Degree of sensitization stereotypy0.00.00.00.20.1-0.1-0.20.10.1-0.2
Condit. Reinf. active minus inactive responses0.20.31.0-0.30.50.41.0-0.3-0.20.4
Condit. Reinf. active-inactive response ratio0.30.31.7-0.00.50.11.3-0.60.10.2
Condit. Reinf. active responses0.10.10.3-0.20.50.20.3-0.0-0.30.4
Condit. Reinf. inactive responses0.60.71.1-0.70.80.6-1.00.9-0.80.8
Incentive salience index mean0.10.20.90.1-0.1-0.11.0-0.50.1-0.0
Condit. Reinf. lever presses0.40.61.00.9-0.7-1.00.5-0.60.6-0.8
Time in familiar zone, hab. session 10.20.20.9-0.10.30.01.0-0.60.30.1
Time in novel zone, hab. session 11.21.21.91.1-1.4-1.10.8-1.01.1-1.0
Total zone transitions, hab. session 10.30.41.70.4-0.0-0.4-1.30.60.0-0.5
Total locomotion distance, hab. session 10.91.32.0-1.11.01.1-1.41.4-1.11.0
Locomotion velocity, hab. session 11.01.42.5-1.01.01.0-1.61.4-1.10.9
Time in familiar zone, hab. session 20.60.60.80.7-0.7-0.80.8-0.90.9-0.8
Time in novel zone, hab. session 20.10.10.1-0.20.40.3-0.30.3-0.20.2
Total zone transitions, hab. session 20.30.40.7-0.70.70.8-0.30.6-0.70.7
Total locomotion distance, hab. session 21.31.72.4-1.41.31.6-0.71.2-1.31.4
Locomotion velocity, hab. session 21.11.52.1-1.31.21.4-0.81.2-1.31.3
Novel to familiar place preference ratio0.20.20.6-0.30.10.20.8-0.40.00.4
Novelty place preference0.10.20.6-0.20.10.10.8-0.50.10.3
Time in novel zone, NPP test0.30.31.2-0.0-0.1-0.01.1-0.70.30.1
Total zone transitions, NPP test0.30.40.6-0.80.70.8-0.20.6-0.70.7
Total locomotion distance, NPP test0.60.81.2-1.00.71.1-0.40.9-0.91.0
Locomotion velocity, NPP test1.01.41.7-1.30.91.3-0.91.3-1.31.2
Pavlov. Cond. lever latency0.50.71.2-0.70.80.9-1.10.8-0.60.8
Pavlov. Cond. magazine entry latency0.20.30.60.4-0.5-0.60.8-0.50.3-0.4
Pavlov. Cond. change in total contacts0.10.10.3-0.40.30.10.5-0.1-0.40.5
Pavlov. Cond. index score0.60.82.30.6-0.9-0.81.5-1.00.6-0.5
Pavlov. Cond. latency score0.70.82.00.7-0.9-0.91.4-1.00.7-0.7
Pavlov. Cond. lever contacts0.40.51.20.5-0.7-0.61.1-0.70.4-0.5
Pavlov. Cond. magazine entry number1.21.52.7-1.11.11.2-1.61.4-1.01.0
Pavlov. Cond. intertrial magazine entries0.40.40.7-0.80.80.80.00.3-0.50.8
Pavlov. Cond. lever-magazine prob. diff.0.30.41.60.2-0.5-0.41.3-0.70.2-0.1
Pavlov. Cond. response bias0.40.51.60.4-0.7-0.61.3-0.80.4-0.4
Bone: apparent density4.67.69.43.0-2.7-3.11.8-2.72.9-2.9
Bone surface0.30.50.80.8-0.9-0.90.3-0.60.7-0.7
Bone volume1.93.24.01.9-1.8-2.01.1-1.71.8-1.9
Bone: connectivity density1.01.62.21.3-1.5-1.40.9-1.21.3-1.2
Bone: cortical apparent density3.34.47.8-1.71.61.8-2.82.6-2.11.7
Bone: cortical area0.20.20.4-0.50.30.5-0.30.5-0.60.5
Bone: cortical porosity1.61.71.91.3-1.4-1.31.2-1.31.3-1.3
Bone: cortical porosity1.71.92.21.5-1.3-1.51.1-1.31.4-1.5
Bone: cortical thickness0.20.30.5-0.60.40.7-0.30.6-0.70.7
Bone: cortical thickness0.10.10.1-0.30.10.2-0.10.2-0.30.3
Bone: cortical tissue density3.24.27.9-1.71.61.7-2.82.5-2.11.6
Bone: elastic displacement1.11.32.30.8-1.5-0.81.5-1.31.1-0.7
Bone: elastic work0.50.70.80.8-0.9-0.80.8-0.90.9-0.8
Bone: endosteal estimation0.00.00.00.00.1-0.10.0-0.10.1-0.1
Bone: endosteal perimeter0.00.00.0-0.10.20.10.2-0.10.00.1
Bone: final force0.50.81.8-0.51.10.6-1.31.1-0.80.5
Bone: final moment0.40.71.7-0.51.00.6-1.31.0-0.70.5
Bone: marrow area0.00.00.00.00.2-0.0-0.0-0.10.1-0.0
Bone: maximum diameter0.00.10.20.2-0.4-0.20.3-0.30.2-0.2
Bone: maximum force0.40.81.6-0.61.10.6-1.31.0-0.80.6
Bone: maximum moment0.40.71.5-0.61.00.6-1.21.0-0.80.6
Bone: minimum diameter0.40.81.1-0.90.60.8-0.91.1-1.10.9
Bone: periosteal estimation0.00.00.00.00.0-0.00.1-0.0-0.00.0
Bone: periosteal perimeter0.00.10.4-0.20.00.20.6-0.2-0.10.2
Bone: post-yield work0.20.30.80.40.2-0.6-0.90.20.2-0.5
Bone: stiffness0.60.92.0-0.41.20.6-1.41.2-0.90.5
Bone: tissue strength0.40.30.6-0.50.80.4-0.70.6-0.60.5
Bone: trabecular number3.25.17.02.6-2.0-2.61.0-2.02.4-2.6
Bone: trabecular spacing2.83.64.5-2.12.02.1-1.21.8-2.02.0
Bone: trabecular thickness5.87.08.22.8-2.5-2.92.2-2.72.7-2.7
Bone: trabecular tissue density0.10.10.30.5-0.0-0.4-0.2-0.10.4-0.6
Breakpoint value in progressive ratio session0.70.82.00.7-0.8-0.61.4-1.10.7-0.5
Distance traveled before self-admin0.30.30.50.4-0.7-0.40.7-0.50.4-0.4
Distance traveled after self-admin2.22.53.91.8-1.5-1.80.5-1.31.7-2.0
Delta time in closed arm before/after self-admin1.00.92.31.1-1.5-1.10.0-0.60.8-0.9
Delta time in open arm before/after self-admin0.10.10.50.2-0.3-0.10.7-0.40.2-0.2
Diff in mean of infusions in LGA sessions2.32.65.51.2-1.9-1.22.3-1.81.3-1.0
Extinction: sum of active levers before priming0.10.10.2-0.00.40.10.5-0.30.2-0.0
Active lever presses in extinction session 61.11.01.7-1.21.11.30.40.4-0.91.3
Delta distance traveled before/after self-admin0.30.40.80.7-0.3-0.7-0.6-0.20.7-0.9
Delta ambulatory time before/after self-admin0.30.30.60.7-0.4-0.6-0.6-0.10.6-0.8
Time in closed arm before self-admin0.20.20.6-0.50.70.50.6-0.3-0.00.4
Time in closed arm after self-admin0.60.71.01.0-0.8-0.90.2-0.70.9-0.9
Time in open arm before self-admin0.20.20.3-0.50.00.4-0.20.5-0.50.5
Time in open arm after self-admin0.40.50.90.5-0.7-0.50.9-0.70.6-0.6
Sum of active levers in priming session hrs 5-61.11.02.70.5-1.1-0.51.6-1.30.9-0.4
Time to tail flick, vehicle, before self-admin0.20.20.3-0.50.50.5-0.20.3-0.30.4
Time to tail flick, vehicle, after self-admin0.10.10.3-0.10.10.00.5-0.40.20.0
Time to tail flick, test, before self-admin0.90.91.4-0.90.80.9-1.21.0-0.90.9
Time to tail flick, test, after self-admin3.53.65.1-1.72.11.7-2.32.0-1.71.7
Delta time to tail flick, vehicle, before/after SA0.10.10.10.2-0.2-0.30.2-0.20.3-0.3
Delta time to tail flick, test, before/after SA0.20.20.3-0.50.60.4-0.20.3-0.30.4
Ambulatory time before self-admin0.20.20.70.1-0.5-0.10.8-0.40.1-0.1
Ambulatory time after self-admin0.30.30.60.6-0.6-0.6-0.3-0.10.5-0.8
Total heroin consumption0.20.20.9-0.10.00.10.9-0.50.10.3
Area under the delay curve0.30.30.6-0.60.50.60.8-0.2-0.20.6
Delay disc. indifference point, 0s delay0.30.30.6-0.50.40.4-0.80.7-0.60.5
Delay disc. indifference point, 16s delay0.40.41.30.10.1-0.11.2-0.90.6-0.2
Delay disc. indifference point, 2s delay0.20.20.4-0.60.40.50.00.2-0.50.7
Delay disc. indifference point, 24s delay0.20.20.40.4-0.1-0.40.6-0.60.5-0.4
Delay disc. indifference point, 4s delay0.60.71.0-0.91.00.8-0.50.7-0.80.8
Delay disc. indifference point, 8s delay0.10.10.5-0.30.10.40.7-0.30.10.3
Delay discount exponential model param0.30.30.70.5-0.5-0.5-0.90.30.1-0.6
Delay discount hyperbolic model param0.40.40.60.8-0.7-0.7-0.5-0.00.4-0.8
Fecal boli incidents, locomotor time 12.02.23.0-1.71.51.6-0.61.2-1.61.7
Change in fecal boli incidents, locomotor task0.30.30.50.5-0.7-0.40.7-0.50.4-0.4
Time >=10cm from walls, locomotor time 11.61.62.3-1.50.91.5-0.61.3-1.51.4
Bouts of movement, locomotor time 17.07.711.0-3.22.93.1-1.02.3-3.03.3
Total resting periods, locomotor time 17.58.311.1-3.23.03.2-1.32.5-3.13.3
Rest time, locomotor task time 10.60.61.2-0.90.80.80.80.0-0.71.1
Distance moved, locomotor task time 10.20.31.00.4-1.0-0.4-0.1-0.20.4-0.5
Vertical activity count, locomotor time 11.11.11.81.2-1.2-1.20.0-0.71.1-1.3
Time >=10cm from walls, locomotor time 20.40.41.9-0.0-0.60.11.4-0.60.10.0
Bouts of movement, locomotor time 23.33.64.2-1.92.12.0-1.71.9-1.81.8
Total resting periods, locomotor time 23.03.23.6-1.81.91.8-1.81.8-1.71.7
Rest time, locomotor task time 20.10.20.30.4-0.3-0.60.4-0.50.3-0.3
Distance moved, locomotor task time 20.20.20.5-0.6-0.30.70.10.4-0.50.6
Vertical activity count, locomotor time 20.30.40.5-0.60.60.7-0.40.7-0.70.6
Weight adjusted by age1.41.53.3-1.10.81.2-1.81.6-1.10.6
Seeking ratio, delayed vs. immediate footshock0.10.10.20.4-0.0-0.30.4-0.50.5-0.4
Locomotion in novel chamber6.88.49.9-3.12.83.1-2.13.0-3.13.0
Locomotion in novel chamber post-restriction4.04.75.7-2.32.42.1-1.82.2-2.22.1
Progressive ratio1.72.03.1-1.81.51.70.00.8-1.31.7
Food seeking constrained by brief footshock0.00.00.1-0.20.30.1-0.20.1-0.10.1
Seeking ratio, punishment vs. effort0.81.01.61.2-1.0-1.2-0.3-0.50.9-1.2
Run reversals in cocaine runway, females1.11.02.0-0.91.10.8-1.41.2-0.90.6
Run reversals in cocaine runway, males0.60.61.0-1.00.91.00.00.5-0.60.7
Latency to leave start box in cocaine runway3.13.44.5-1.71.91.7-2.12.1-1.91.6
Latency to leave start box in cocaine runway, F0.40.41.5-0.30.40.3-1.20.9-0.50.1
Latency to leave start box in cocaine runway, M4.84.65.3-2.22.12.2-1.82.2-2.32.3
Cd content in liver0.10.10.10.3-0.1-0.40.2-0.30.3-0.3
Co content in liver0.40.40.80.7-0.0-0.50.9-0.80.7-0.6
Cu content in liver0.50.60.80.8-0.1-0.90.9-0.90.8-0.8
Fe content in liver2.53.03.61.9-1.5-1.81.4-1.81.8-1.9
K content in liver1.51.52.5-1.10.81.0-1.61.5-1.31.1
Mg content in liver0.40.41.0-0.40.30.4-1.00.8-0.60.4
Mn content in liver0.50.51.5-0.50.50.4-1.20.9-0.70.5
Na content in liver0.80.92.21.0-1.5-1.00.0-0.50.8-1.0
Rb content in liver3.34.25.1-2.02.32.3-1.62.1-2.12.0
Se content in liver0.20.30.4-0.60.60.5-0.20.4-0.60.6
Sr content in liver0.10.10.5-0.1-0.30.10.7-0.30.00.2
Zn content in liver0.00.00.10.10.3-0.10.3-0.20.1-0.1