Hub : Genes

Mfn1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS ENSRNOT00000077170 0.04 0.03 1.3e-04 0.02 0.03 0.01 0.02 2.3e-03 3.5e-04 6.6e-02 2.6e-03
2 Adipose alternative TSS ENSRNOT00000098575 0.05 0.03 1.4e-04 0.02 0.03 0.01 0.02 2.4e-03 3.1e-04 4.3e-02 1.6e-03
3 Adipose gene expression ENSRNOG00000011057 0.16 0.07 0.0e+00 0.17 0.18 0.17 0.17 5.8e-19 3.7e-19 1.9e-18 6.0e-19
4 Adipose isoform ratio ENSRNOT00000098575 0.04 0.03 2.7e-04 0.02 0.03 0 0.02 2.0e-03 3.8e-04 7.6e-02 1.3e-03
5 Adipose mRNA stability ENSRNOG00000011057 0.12 0.09 4.6e-06 0.03 0.04 0.04 0.04 8.2e-04 3.2e-05 6.6e-05 5.5e-05
6 BLA gene expression ENSRNOG00000011057 0.11 0.06 4.9e-06 0.06 0.08 0.05 0.07 3.6e-04 4.0e-05 1.7e-03 2.0e-04
7 BLA mRNA stability ENSRNOG00000011057 0.11 0.07 1.9e-05 0.1 0.08 0.07 0.1 8.0e-06 3.5e-05 8.7e-05 6.1e-06
8 Brain gene expression ENSRNOG00000011057 0.27 0.11 0.0e+00 0.31 0.32 0.32 0.32 4.8e-29 8.8e-30 4.8e-30 1.0e-30
9 Brain mRNA stability ENSRNOG00000011057 0.04 0.03 1.6e-03 0.02 0.02 0.03 0.02 5.3e-03 3.5e-03 1.8e-03 9.3e-03
10 IL gene expression ENSRNOG00000011057 0.17 0.1 4.8e-04 0.16 0.12 0.14 0.14 9.8e-05 9.1e-04 2.7e-04 3.5e-04
11 LHb gene expression ENSRNOG00000011057 0.54 0.24 7.6e-05 0.2 0.18 0.2 0.16 1.3e-05 3.9e-05 1.4e-05 1.4e-04
12 Liver gene expression ENSRNOG00000011057 0.31 0.12 0.0e+00 0.33 0.32 0.33 0.34 2.9e-37 2.2e-36 2.2e-37 2.9e-38
13 NAcc gene expression ENSRNOG00000011057 0.19 0.1 5.6e-16 0.2 0.2 0.18 0.2 1.3e-14 1.8e-14 1.9e-13 1.6e-14
14 PL gene expression ENSRNOG00000011057 0.13 0.06 8.2e-14 0.19 0.17 0.16 0.17 3.6e-14 3.4e-13 4.2e-12 2.6e-13
15 PL mRNA stability ENSRNOG00000011057 0.06 0.03 4.1e-06 0.08 0.07 0.06 0.07 8.1e-07 3.7e-06 4.1e-05 2.4e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.61.93.3-1.21.1-1.31.1-0.6-1.81.4-1.51.4-1.5-1.4-1.5-1.4-1.41.5
BMI without tail1.22.53.3-1.41.4-1.61.4-1.3-1.81.6-1.61.8-1.7-1.6-1.6-1.6-1.61.8
Body weight0.00.10.80.2-0.20.3-0.30.9-0.4-0.1-0.00.60.10.10.10.10.10.1
Epididymis fat weight0.81.83.41.3-1.31.5-1.41.81.1-1.31.3-0.81.41.41.41.31.4-1.3
Glucose1.62.53.21.5-1.51.5-1.51.11.8-1.71.7-1.11.71.71.71.71.7-1.5
Heart weight0.40.61.0-0.80.8-0.70.8-0.5-0.71.0-0.7-0.2-0.8-0.8-0.9-1.0-0.80.8
Left kidney weight0.20.50.9-0.90.9-0.60.9-0.4-0.50.7-0.70.6-0.7-0.6-0.7-0.7-0.60.6
Right kidney weight0.31.01.5-0.90.8-0.90.8-0.4-1.21.0-1.11.2-1.1-1.0-1.0-1.0-1.01.1
Tail length0.00.10.2-0.30.3-0.20.3-0.40.1-0.10.10.4-0.2-0.10.00.1-0.20.2
Length with tail0.20.71.00.5-0.50.9-0.60.81.0-1.00.9-0.20.80.91.01.00.9-0.7
Length without tail1.02.13.11.0-1.01.6-1.01.61.7-1.41.4-1.81.51.51.51.41.5-1.5
Liver weight, left1.72.74.02.0-2.01.7-2.01.81.1-1.41.7-0.51.61.71.61.41.7-1.8
Liver weight, right0.10.10.20.4-0.40.3-0.40.30.3-0.30.4-0.50.40.40.30.30.4-0.5
Parametrial fat weight0.10.21.20.5-0.50.6-0.51.1-0.0-0.30.3-0.30.30.30.30.30.3-0.3
Retroperitoneal fat weight0.30.92.10.8-0.81.1-0.81.50.7-0.80.7-1.30.90.90.80.80.9-0.8
Intraocular pressure0.91.22.01.1-1.11.1-1.11.01.2-0.81.0-1.41.21.31.00.81.3-1.3
Extensor digitorum longus weight0.00.20.90.1-0.1-0.0-0.10.9-0.90.4-0.30.4-0.3-0.3-0.3-0.4-0.30.6
Soleus weight11.032.035.8-5.95.9-5.75.8-5.1-5.35.8-6.04.6-5.7-5.7-5.9-5.8-5.76.0
Tibialis anterior weight0.20.51.8-0.30.3-0.40.30.5-1.30.8-0.70.2-0.8-0.8-0.8-0.8-0.81.0
Tibia length3.49.611.82.7-2.63.2-2.73.13.3-3.23.1-3.03.13.23.33.23.2-3.4
Number of licking bursts1.01.22.4-0.60.6-1.10.6-0.8-1.51.0-1.51.5-1.2-1.2-0.8-1.0-1.21.3
Food consumed during 24 hour testing period0.00.00.1-0.10.10.00.00.00.10.00.20.20.10.10.1-0.00.1-0.0
Times rat made contact with spout1.21.32.01.1-1.11.1-1.10.81.2-1.21.4-0.71.21.21.31.21.2-1.2
Mean time between licks in bursts0.60.92.30.4-0.40.9-0.40.51.5-1.10.9-1.01.11.00.91.11.1-1.0
Mean num. licks in bursts1.72.03.91.1-1.01.4-1.11.01.8-1.32.0-1.41.61.51.21.31.6-1.6
Std. dev. time between licks in bursts0.30.41.10.2-0.20.6-0.20.60.8-1.10.8-0.00.60.60.71.10.6-0.5
Water consumed over 24 hours0.00.00.10.00.00.10.00.10.1-0.00.2-0.30.00.00.20.00.0-0.0
Indifference point 0 sec0.91.52.1-1.11.1-1.41.1-1.3-1.40.9-1.30.9-1.4-1.4-1.1-0.9-1.41.5
Indifference point AUC0.91.13.9-0.40.3-0.80.30.1-1.81.0-0.92.0-1.1-1.1-1.0-1.0-1.10.9
Indifference point function ln k0.81.13.20.4-0.40.9-0.40.01.8-1.21.1-1.51.21.21.11.21.2-1.0
Indifference point function log k0.81.13.20.4-0.40.9-0.40.01.8-1.21.1-1.51.21.21.11.21.2-1.0
Delay discounting total patch changes 0 sec1.01.72.2-1.11.1-1.41.1-1.3-1.50.9-1.41.1-1.5-1.5-1.2-0.9-1.51.5
Delay discounting total patch changes 12 sec1.21.52.7-1.00.9-1.30.9-1.0-1.61.0-1.11.5-1.4-1.5-1.2-1.0-1.41.4
Delay discounting total patch changes 18 sec1.01.32.9-0.70.7-1.20.7-0.7-1.60.8-1.11.7-1.3-1.4-1.0-0.8-1.31.1
Delay discounting total patch changes 24 sec4.45.58.5-2.02.0-2.42.0-1.7-2.92.3-2.32.2-2.6-2.6-2.5-2.3-2.62.5
Delay discounting total patch changes 6 sec3.95.98.6-2.12.0-2.62.1-2.1-2.92.1-2.52.4-2.8-2.8-2.4-2.1-2.82.6
Delay discounting time to switch 0 sec0.00.10.4-0.00.00.10.0-0.30.5-0.10.2-0.60.20.20.10.10.2-0.3
Delay discounting water rate 0 sec0.40.61.2-0.80.8-0.80.8-0.6-0.90.4-0.71.1-0.9-0.9-0.7-0.4-0.90.9
Delay discounting water rate 12 sec0.00.10.4-0.10.1-0.10.1-0.40.3-0.20.1-0.60.0-0.00.10.20.00.1
Delay discounting water rate 18 sec0.30.40.60.7-0.70.6-0.70.70.3-0.80.6-0.60.50.50.60.80.5-0.4
Delay discounting water rate 24 sec1.11.52.5-1.11.1-1.21.1-0.8-1.51.0-1.20.6-1.4-1.4-1.2-1.0-1.41.6
Delay discounting water rate 6 sec0.00.00.0-0.00.0-0.10.0-0.1-0.2-0.2-0.0-0.1-0.1-0.1-0.00.2-0.10.2
Locomotor activity2.13.36.41.5-1.42.0-1.51.92.0-1.41.6-2.51.92.01.71.41.9-2.1
Locomotor testing distance1.01.74.31.2-1.11.5-1.21.61.2-0.91.2-2.11.21.31.10.91.2-1.3
Locomotor testing rearing0.10.21.90.2-0.10.4-0.10.40.5-0.10.4-1.40.30.30.20.10.3-0.3
Light reinforcement 10.30.52.10.2-0.10.6-0.10.31.1-0.60.6-1.50.70.70.60.60.7-0.7
Light reinforcement 20.00.10.10.2-0.20.3-0.20.40.2-0.30.1-0.10.30.30.20.30.3-0.3
Reaction time number correct3.65.17.72.7-2.82.4-2.72.51.7-1.92.0-1.72.32.32.11.92.3-2.3
Reaction time mean minus median0.00.10.50.1-0.20.0-0.2-0.20.2-0.2-0.00.70.20.30.20.20.2-0.2
Reaction time mean minus median AUC0.10.21.0-0.20.1-0.40.2-0.5-0.40.3-0.51.0-0.3-0.3-0.3-0.3-0.30.3
Reaction time num false alarms0.00.00.1-0.10.1-0.10.10.0-0.10.2-0.1-0.2-0.1-0.1-0.1-0.2-0.10.2
Reaction time num false alarms AUC0.00.00.00.2-0.20.1-0.20.2-0.10.00.0-0.20.10.10.1-0.00.10.0
Reaction time trials correct on left3.65.17.72.7-2.82.4-2.72.51.7-1.92.0-1.72.32.32.11.92.3-2.3
Reaction time trials on left3.75.37.82.8-2.82.4-2.82.51.7-1.92.0-1.72.42.32.11.92.4-2.3
Reaction time mean1.52.12.61.4-1.41.4-1.40.91.6-1.61.5-0.81.51.51.61.61.5-1.6
Reaction time mean AUC1.21.52.11.2-1.21.2-1.20.71.5-1.41.3-0.81.31.41.31.41.3-1.4
Median of all reaction times1.41.92.41.4-1.41.3-1.40.91.5-1.51.4-0.91.41.51.51.51.4-1.5
Reaction time omissions0.30.31.3-0.10.10.40.0-0.11.2-0.60.5-0.40.70.70.60.60.7-0.7
Reaction time false alarm rate0.91.31.6-1.31.3-1.21.3-1.1-1.01.1-1.10.7-1.2-1.2-1.1-1.1-1.21.3
Reaction time premature initiation rate0.91.21.8-1.21.2-1.21.2-1.3-0.80.9-1.00.9-1.1-1.1-1.0-0.9-1.11.2
Reaction time premature initiations0.10.10.20.5-0.50.3-0.50.20.2-0.30.3-0.20.40.40.30.30.4-0.2
Std. dev. reaction times0.10.20.30.4-0.40.3-0.40.10.5-0.50.30.50.50.50.50.50.5-0.4
Reaction time trials completed3.75.37.82.8-2.82.4-2.82.51.7-1.92.0-1.72.42.32.11.92.4-2.3
Reaction time trials AUC3.55.17.22.7-2.72.4-2.72.51.7-1.92.0-1.72.32.32.11.92.3-2.2
Social response proportion2.83.04.01.5-1.41.6-1.41.12.0-2.02.0-1.91.71.71.92.01.7-1.7
Social responses0.00.10.1-0.10.1-0.20.2-0.2-0.30.0-0.1-0.4-0.4-0.3-0.1-0.0-0.40.3
Social time2.73.56.51.4-1.41.8-1.40.92.6-1.72.1-2.02.12.11.91.72.1-2.1
Conditioned locomotion0.10.10.7-0.60.6-0.40.6-0.90.30.2-0.10.1-0.2-0.2-0.2-0.2-0.20.1
Cocaine response after cond. corrected0.10.10.3-0.30.3-0.10.3-0.60.40.0-0.10.30.10.10.0-0.00.1-0.1
Cocaine response after cond. not corrected0.30.30.80.3-0.30.5-0.30.20.9-0.50.6-0.20.70.60.60.50.7-0.6
Cocaine response before conditioning0.10.10.50.2-0.20.4-0.20.70.0-0.20.3-0.60.10.10.20.20.1-0.1
Saline control response0.60.72.30.6-0.61.0-0.61.00.9-0.60.7-1.50.90.80.80.60.9-0.9
Condit. Reinf. active minus inactive responses1.41.72.71.2-1.11.4-1.11.41.3-1.41.6-1.41.21.21.41.41.2-1.2
Condit. Reinf. active-inactive response ratio1.11.22.00.9-0.81.1-0.90.81.3-1.11.4-0.81.21.21.21.11.2-1.1
Condit. Reinf. active responses3.24.57.02.0-2.02.3-2.02.61.8-2.22.2-2.12.02.02.22.22.0-1.9
Condit. Reinf. inactive responses2.12.65.01.8-1.81.7-1.82.21.0-1.61.4-1.61.41.41.51.61.4-1.4
Condit. Reinf. lever presses0.30.40.60.5-0.40.7-0.50.70.6-0.80.8-0.60.50.50.70.80.5-0.4
Condit. Reinf. lever reinforcers received3.04.26.61.9-1.92.2-1.92.61.7-2.12.2-2.01.91.92.12.11.9-1.9
Pavlov. Cond. lever latency0.10.10.30.0-0.00.2-0.0-0.20.50.00.1-0.60.30.40.1-0.00.3-0.4
Pavlov. Cond. magazine entry latency0.10.11.30.0-0.1-0.2-0.0-0.2-0.2-0.1-0.11.2-0.1-0.20.00.1-0.10.1
Pavlov. Cond. change in total contacts0.81.21.91.2-1.21.1-1.21.40.7-1.21.2-0.41.00.91.21.21.0-0.9
Pavlov. Cond. index score0.10.10.60.3-0.30.0-0.30.4-0.4-0.20.10.7-0.1-0.10.10.2-0.10.1
Pavlov. Cond. latency score0.10.10.60.3-0.40.1-0.40.4-0.3-0.30.20.8-0.0-0.00.20.3-0.0-0.0
Pavlov. Cond. lever contacts0.30.40.7-0.50.5-0.60.5-0.4-0.80.4-0.50.8-0.8-0.8-0.5-0.4-0.80.8
Pavlov. Cond. magazine entry number0.20.21.30.1-0.10.4-0.10.10.8-0.30.4-1.10.50.50.40.30.5-0.4
Pavlov. Cond. intertrial magazine entries0.20.21.50.3-0.20.5-0.30.80.3-0.20.3-1.20.30.30.30.20.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.4-0.40.2-0.40.5-0.3-0.30.20.70.0-0.00.20.30.0-0.0
Pavlov. Cond. response bias0.20.30.7-0.40.3-0.50.4-0.3-0.70.2-0.30.8-0.6-0.6-0.4-0.2-0.60.7
Conditioned reinforcement - actives0.50.50.80.8-0.80.7-0.80.40.7-0.50.6-0.90.80.80.70.50.8-0.8
Conditioned reinforcement - inactives0.00.00.10.2-0.20.2-0.20.20.1-0.10.10.10.20.20.20.10.2-0.2
Conditioned locomotion0.70.91.71.3-1.31.0-1.21.30.3-0.70.6-1.30.80.80.70.70.8-0.8
Intermittent access intake day 1-15 change0.40.41.0-0.30.2-0.60.3-0.4-1.00.6-0.71.0-0.7-0.7-0.5-0.6-0.70.7
Intermittent access intake escalation0.30.31.4-0.20.1-0.50.2-0.2-0.90.4-0.51.2-0.6-0.6-0.4-0.4-0.60.6
Intermittent access intake escalation 20.20.20.40.5-0.60.4-0.50.60.1-0.60.5-0.00.20.20.50.60.2-0.2
Intermitt. access day 1 inactive lever presses0.10.10.40.2-0.20.3-0.20.20.3-0.20.3-0.60.30.30.30.20.3-0.3
Intermitt. access day 15 inactive lever presses0.80.91.51.2-1.20.8-1.20.80.6-1.00.9-0.10.90.90.81.00.9-0.9
Intermitt. access escalation Index0.00.00.00.0-0.00.1-0.00.00.20.00.0-0.20.20.20.0-0.00.2-0.2
Intermittent access day 1 total infusions3.94.44.92.2-2.22.2-2.22.02.0-1.92.1-1.72.22.22.11.92.2-2.2
Intermittent access day 15 total infusions0.70.71.71.3-1.30.8-1.31.10.2-0.60.7-0.10.80.80.70.60.8-0.8
Intermittent access terminal intake (last 3 days)2.73.04.62.1-2.21.8-2.12.01.1-1.51.6-0.91.71.71.71.51.7-1.7
Intermittent access total infusions2.42.74.32.0-2.11.7-2.01.91.1-1.31.5-1.11.61.61.61.31.6-1.6
Intermittent access day 1 locomotion1.01.11.51.2-1.21.1-1.11.20.8-0.80.9-1.21.01.00.90.81.0-1.0
Intermittent access day 15 total locomotion0.60.61.7-0.30.3-0.70.3-0.2-1.30.9-1.00.3-0.9-0.9-0.9-0.9-0.90.9
Intermittent access total locomotion0.30.41.21.0-1.10.6-1.01.1-0.3-0.20.2-0.50.30.30.30.20.3-0.3
Intermittent access standard deviation0.10.10.6-0.30.3-0.40.3-0.3-0.40.2-0.30.8-0.4-0.4-0.3-0.2-0.40.4
Cocaine induced anxiety0.50.61.11.0-1.00.8-1.01.00.4-0.80.7-0.40.70.70.90.80.7-0.7
Post-drug Anxiety1.92.02.91.7-1.71.4-1.71.51.0-1.41.4-1.21.41.41.51.41.4-1.4
Baseline Anxiety0.30.30.8-0.60.6-0.70.6-0.9-0.40.3-0.40.4-0.6-0.6-0.6-0.3-0.60.6
Lifetime Intake3.03.44.82.2-2.21.9-2.22.01.4-1.61.7-1.31.91.91.81.61.9-1.9
Incentive Sensitization - Responses0.10.10.50.6-0.70.2-0.60.7-0.50.2-0.10.30.10.1-0.1-0.20.1-0.1
Incentive Sensitization - Breakpoint0.20.20.80.8-0.90.4-0.90.8-0.40.00.10.20.30.30.1-0.00.3-0.3
Progressive ratio test 1 active lever presses1.92.02.51.5-1.51.5-1.51.61.2-1.21.3-1.61.41.41.31.21.4-1.4
Progressive ratio test 1 breakpoint2.12.22.91.6-1.61.6-1.61.71.2-1.31.4-1.71.51.51.41.31.5-1.5
Progressive ratio test 1 inactive lever presses1.21.31.71.3-1.31.1-1.31.20.9-1.01.1-1.11.11.11.11.01.1-1.1
Progressive ratio test 2 active lever presses1.11.22.51.6-1.61.1-1.61.50.4-0.70.9-0.51.01.00.90.71.0-1.0
Progressive ratio test 2 breakpoint0.70.82.01.4-1.40.9-1.41.20.1-0.50.6-0.50.80.80.60.50.8-0.8
Progressive ratio test 2 inactive lever presses0.91.01.91.3-1.40.9-1.41.10.5-0.90.9-0.20.90.90.90.90.9-0.9
Total sessions with >9 infusions1.51.62.71.0-1.01.3-1.00.91.6-1.11.2-1.61.41.41.31.11.4-1.4
Short access day 1 total inactive lever presses0.50.61.7-0.30.3-0.60.3-0.1-1.31.0-1.00.2-0.8-0.8-1.0-1.0-0.80.8
Short access day 10 total inactive lever presses1.41.52.4-1.11.1-1.21.1-1.0-1.41.2-1.31.5-1.2-1.2-1.3-1.2-1.21.2
Short access day 1 total infusions0.91.01.41.0-1.01.0-1.01.10.8-0.90.9-1.20.90.90.90.90.9-0.9
Short access day 10 total infusions1.92.12.41.6-1.61.5-1.51.51.3-1.31.4-1.21.51.51.51.31.5-1.5
Short access total infusions2.62.93.21.8-1.81.8-1.81.71.5-1.51.6-1.61.81.81.71.51.8-1.8
Short access day 1 locomotion0.30.30.7-0.20.1-0.40.2-0.1-0.90.7-0.7-0.0-0.5-0.5-0.6-0.7-0.50.5
Short access day 10 total locomotion0.40.50.9-0.50.5-0.60.5-0.3-0.90.7-0.80.8-0.8-0.8-0.7-0.7-0.80.8
Short access total locomotion0.50.51.30.9-0.90.8-0.90.80.5-0.40.5-1.10.70.70.60.40.7-0.7
Compulsive drug intake0.30.30.70.4-0.40.6-0.40.70.6-0.80.6-0.70.50.50.60.80.5-0.5
One hour access (0.3 mA shock)1.01.22.11.4-1.41.1-1.41.30.6-1.01.0-0.41.01.01.11.01.0-1.0
One hour access (shock baseline)1.41.62.71.6-1.61.2-1.61.30.8-1.11.2-0.41.31.31.31.11.3-1.3
Number of responses in last shaping day0.30.30.8-0.10.1-0.50.2-0.3-0.90.6-0.70.3-0.6-0.6-0.6-0.6-0.60.6
Context. condit. distance diff. score4.55.56.6-2.52.5-2.42.5-2.5-2.02.6-2.31.7-2.3-2.3-2.4-2.6-2.32.3
Locomotion velocity, session 12.32.45.72.0-2.01.7-2.02.40.7-1.21.3-1.01.51.51.41.21.5-1.4
Locomotion distance, session 10.60.82.61.2-1.21.0-1.21.60.1-0.70.7-0.20.70.70.80.70.7-0.6
Locomotion velocity, session 23.64.27.32.6-2.72.2-2.62.71.1-1.91.6-1.31.91.92.01.91.9-1.7
Locomotion distance, session 21.31.83.61.6-1.61.5-1.61.90.8-1.31.2-0.91.21.21.31.31.2-1.2
Locomotion velocity, session 30.00.00.20.2-0.20.2-0.20.5-0.0-0.10.2-0.10.10.10.20.10.1-0.1
Locomotion distance, session 30.30.30.60.8-0.80.5-0.80.50.4-0.60.3-0.20.50.50.60.60.5-0.5
Stereotopy head waving bouts, day 30.10.10.50.3-0.30.3-0.30.30.2-0.10.4-0.70.30.30.20.10.3-0.3
Stereotopy head waving duration, day 30.50.70.9-0.70.7-0.80.7-0.7-0.91.0-0.60.4-0.9-0.9-0.9-1.0-0.90.9
Locomotion velocity, session 70.80.91.60.8-0.71.0-0.81.30.8-1.01.1-1.30.80.81.01.00.8-0.8
Locomotion distance, session 70.60.81.00.7-0.70.9-0.70.81.0-1.00.9-0.90.90.90.91.00.9-0.9
Stereotopy head waving bouts, day 71.11.22.4-0.70.6-1.10.7-0.7-1.61.1-1.01.5-1.2-1.2-1.1-1.1-1.21.2
Stereotopy head waving duration, day 71.11.32.7-0.80.7-1.10.8-0.6-1.71.2-1.11.3-1.3-1.3-1.2-1.2-1.31.3
Locomotion velocity, session 81.72.03.3-1.11.1-1.41.1-0.9-1.81.4-1.51.5-1.5-1.5-1.5-1.4-1.51.6
Locomotion distance, session 80.71.11.6-1.11.1-0.91.1-0.7-0.91.3-0.90.7-1.0-1.0-1.1-1.3-1.01.0
Degree of sensitization distance0.70.71.50.4-0.40.8-0.40.51.2-0.81.0-1.10.90.90.80.80.9-0.9
Degree of sensitization stereotypy1.71.83.2-1.00.9-1.41.0-1.0-1.71.3-1.31.8-1.5-1.5-1.3-1.3-1.51.5
Condit. Reinf. active minus inactive responses2.02.22.71.5-1.41.6-1.51.61.4-1.51.4-1.41.51.51.51.51.5-1.4
Condit. Reinf. active-inactive response ratio1.41.62.01.1-1.11.3-1.11.11.4-1.21.3-1.21.31.31.31.21.3-1.3
Condit. Reinf. active responses1.31.53.31.3-1.31.4-1.31.80.8-1.21.2-1.51.11.11.21.21.1-1.0
Condit. Reinf. inactive responses0.10.10.80.2-0.20.1-0.10.9-0.70.1-0.1-0.5-0.3-0.3-0.2-0.1-0.30.3
Incentive salience index mean2.22.63.61.6-1.61.7-1.61.91.4-1.61.7-1.41.71.71.61.61.7-1.5
Condit. Reinf. lever presses0.81.02.61.0-1.01.2-1.01.60.7-0.91.2-0.81.01.00.90.91.0-0.9
Time in familiar zone, hab. session 10.20.20.50.6-0.70.4-0.70.60.1-0.10.20.40.50.50.20.10.5-0.4
Time in novel zone, hab. session 12.52.43.1-1.71.7-1.61.7-1.7-1.31.4-1.50.5-1.7-1.7-1.5-1.4-1.71.7
Total zone transitions, hab. session 10.40.51.1-0.60.6-0.60.6-0.0-1.00.7-0.60.8-0.9-0.9-0.7-0.7-0.90.9
Total locomotion distance, hab. session 12.33.44.2-1.81.8-1.81.8-1.2-2.11.9-1.71.1-2.0-2.0-1.9-1.9-2.02.1
Locomotion velocity, hab. session 12.02.93.6-1.71.7-1.61.7-1.1-1.91.8-1.61.0-1.9-1.9-1.8-1.8-1.91.9
Time in familiar zone, hab. session 20.00.00.1-0.00.00.1-0.00.10.2-0.10.0-0.10.20.20.10.10.2-0.2
Time in novel zone, hab. session 21.21.21.5-1.01.0-1.11.1-1.2-1.11.1-1.10.4-1.2-1.2-1.1-1.1-1.21.2
Total zone transitions, hab. session 20.10.10.40.4-0.40.3-0.40.6-0.1-0.20.4-0.00.10.10.30.20.1-0.1
Total locomotion distance, hab. session 20.10.10.3-0.20.2-0.30.20.0-0.50.4-0.20.0-0.4-0.4-0.3-0.4-0.40.4
Locomotion velocity, hab. session 20.00.00.10.1-0.10.0-0.10.3-0.30.20.0-0.1-0.2-0.2-0.1-0.2-0.20.1
Novel to familiar place preference ratio8.89.310.0-3.13.1-3.23.1-3.1-2.83.1-3.12.7-3.0-3.0-3.2-3.1-3.02.9
Novelty place preference11.311.712.7-3.53.5-3.63.5-3.5-3.23.5-3.52.9-3.4-3.4-3.5-3.5-3.43.4
Time in novel zone, NPP test12.312.913.9-3.73.7-3.73.7-3.7-3.33.7-3.73.0-3.6-3.6-3.7-3.7-3.63.5
Total zone transitions, NPP test1.42.14.71.7-1.71.6-1.72.20.8-1.31.1-0.81.31.31.41.31.3-1.3
Total locomotion distance, NPP test0.50.71.91.0-1.00.9-1.01.40.3-0.70.6-0.50.70.70.80.70.7-0.6
Locomotion velocity, NPP test0.81.12.71.2-1.21.2-1.21.60.6-1.01.0-0.80.90.91.11.00.9-0.9
Pavlov. Cond. lever latency1.82.33.3-1.61.6-1.61.6-1.8-1.21.5-1.70.6-1.6-1.6-1.6-1.5-1.61.4
Pavlov. Cond. magazine entry latency0.00.10.6-0.10.1-0.10.10.3-0.30.2-0.20.8-0.0-0.0-0.2-0.2-0.00.2
Pavlov. Cond. change in total contacts0.60.61.30.8-0.90.8-0.91.10.3-0.70.80.50.80.80.70.70.8-0.7
Pavlov. Cond. index score0.70.92.61.1-1.21.0-1.21.60.2-0.70.80.50.90.90.80.70.9-0.7
Pavlov. Cond. latency score1.21.53.41.4-1.51.3-1.51.80.6-1.11.20.11.31.31.21.11.3-1.1
Pavlov. Cond. lever contacts1.92.24.11.6-1.61.6-1.62.01.1-1.31.6-0.61.51.51.51.31.5-1.3
Pavlov. Cond. magazine entry number0.20.22.0-0.20.30.10.3-0.60.8-0.30.2-1.40.10.10.20.30.1-0.3
Pavlov. Cond. intertrial magazine entries0.20.20.50.2-0.10.3-0.10.00.7-0.70.7-0.30.30.30.60.70.3-0.5
Pavlov. Cond. lever-magazine prob. diff.0.40.51.90.9-0.90.7-1.01.4-0.0-0.40.50.60.70.70.50.40.7-0.5
Pavlov. Cond. response bias0.10.21.00.4-0.40.2-0.40.8-0.60.2-0.01.00.10.1-0.1-0.20.10.1
Bone: apparent density3.55.86.8-2.52.5-2.42.5-2.2-2.32.4-2.51.8-2.5-2.5-2.5-2.4-2.52.6
Bone surface0.20.30.7-0.80.8-0.40.8-0.2-0.30.4-0.4-0.2-0.5-0.5-0.5-0.4-0.50.5
Bone volume0.40.61.4-1.11.2-0.71.1-0.7-0.40.7-0.70.1-0.7-0.7-0.7-0.7-0.70.9
Bone: connectivity density1.82.93.4-1.61.6-1.71.6-1.4-1.81.7-1.81.3-1.8-1.8-1.8-1.7-1.81.8
Bone: cortical apparent density0.00.00.1-0.10.2-0.20.2-0.3-0.10.2-0.3-0.1-0.1-0.1-0.2-0.2-0.10.2
Bone: cortical area0.10.20.8-0.70.7-0.10.7-0.30.30.2-0.2-0.9-0.1-0.1-0.2-0.2-0.10.2
Bone: cortical porosity0.00.00.1-0.20.3-0.20.3-0.4-0.00.2-0.3-0.3-0.1-0.1-0.2-0.2-0.10.3
Bone: cortical porosity0.10.10.3-0.40.5-0.20.5-0.3-0.00.3-0.4-0.5-0.2-0.2-0.3-0.3-0.20.3
Bone: cortical thickness0.30.51.2-1.11.1-0.61.1-0.9-0.00.7-0.6-0.2-0.5-0.5-0.6-0.7-0.50.6
Bone: cortical thickness0.30.40.90.9-1.00.6-0.90.90.1-0.40.4-0.20.60.50.50.40.6-0.4
Bone: cortical tissue density0.00.00.1-0.10.1-0.20.2-0.3-0.10.2-0.3-0.1-0.2-0.1-0.2-0.2-0.20.2
Bone: elastic displacement0.10.10.6-0.20.2-0.20.3-0.70.40.20.4-0.20.00.0-0.0-0.20.00.0
Bone: elastic work0.50.72.70.2-0.10.7-0.20.21.4-0.61.1-1.60.80.80.80.60.8-0.7
Bone: endosteal estimation0.51.13.40.7-0.71.2-0.71.50.9-1.01.1-1.80.90.91.01.00.9-0.9
Bone: endosteal perimeter0.61.21.91.0-1.01.2-1.01.41.0-1.21.2-1.21.11.11.11.21.1-1.0
Bone: final force0.30.53.00.2-0.20.7-0.20.90.7-0.50.5-1.70.60.50.50.50.6-0.4
Bone: final moment0.20.32.5-0.10.10.50.10.60.6-0.30.2-1.60.30.30.30.30.3-0.2
Bone: marrow area0.40.92.70.6-0.61.0-0.61.40.8-0.90.9-1.70.80.80.80.90.8-0.8
Bone: maximum diameter0.00.00.3-0.30.30.10.30.20.1-0.00.0-0.6-0.0-0.0-0.00.0-0.00.1
Bone: maximum force0.40.73.60.3-0.20.8-0.30.81.1-0.80.7-1.90.80.70.70.80.8-0.6
Bone: maximum moment0.30.53.40.1-0.00.7-0.00.51.0-0.60.6-1.80.60.60.60.60.6-0.5
Bone: minimum diameter0.61.03.70.3-0.21.0-0.20.91.5-1.01.0-1.91.01.01.01.01.0-0.9
Bone: periosteal estimation0.20.52.90.1-0.00.7-0.10.90.8-0.60.6-1.70.60.50.50.60.6-0.5
Bone: periosteal perimeter0.20.31.30.1-0.00.5-0.00.50.7-0.50.6-1.10.50.50.50.50.5-0.4
Bone: post-yield work1.92.63.11.8-1.81.6-1.81.41.5-1.81.8-0.81.71.71.81.81.7-1.5
Bone: stiffness0.10.20.90.00.00.4-0.00.20.7-0.40.2-0.90.40.40.40.40.4-0.3
Bone: tissue strength0.30.31.1-0.80.90.10.9-0.51.0-0.20.2-1.10.10.10.10.20.1-0.2
Bone: trabecular number6.19.511.9-2.72.7-3.12.7-2.7-3.43.2-3.22.8-3.2-3.2-3.3-3.2-3.23.3
Bone: trabecular spacing3.84.97.11.8-1.82.2-1.81.72.7-2.32.3-2.02.42.42.42.32.4-2.2
Bone: trabecular thickness0.50.61.0-0.80.8-0.80.8-1.0-0.50.7-0.70.7-0.7-0.7-0.7-0.7-0.70.8
Bone: trabecular tissue density0.40.51.20.3-0.30.6-0.40.21.1-0.90.90.10.80.80.90.90.8-0.9
Breakpoint value in progressive ratio session2.32.64.4-1.21.2-1.61.2-1.2-2.11.7-1.80.9-1.8-1.8-1.7-1.7-1.81.8
Distance traveled before self-admin1.92.12.8-1.41.4-1.41.4-1.2-1.51.4-1.61.5-1.4-1.4-1.5-1.4-1.41.7
Distance traveled after self-admin0.30.30.8-0.30.3-0.60.3-0.3-0.90.3-0.50.7-0.7-0.7-0.6-0.3-0.70.8
Delta time in closed arm before/after self-admin0.30.30.5-0.70.7-0.40.7-0.2-0.40.6-0.6-0.0-0.4-0.4-0.5-0.6-0.40.6
Delta time in open arm before/after self-admin0.40.40.80.7-0.70.4-0.70.20.5-0.80.80.30.50.50.60.80.5-0.9
Diff in mean of infusions in LGA sessions0.40.40.7-0.80.9-0.60.8-0.6-0.50.6-0.6-0.0-0.6-0.6-0.8-0.6-0.60.6
Extinction: sum of active levers before priming0.20.20.60.3-0.20.4-0.20.20.5-0.60.4-0.80.30.30.30.60.3-0.2
Active lever presses in extinction session 60.10.10.1-0.20.2-0.30.2-0.4-0.20.3-0.3-0.4-0.3-0.3-0.1-0.3-0.30.3
Delta distance traveled before/after self-admin1.11.21.61.3-1.31.1-1.21.00.9-1.01.1-0.91.01.01.01.01.0-1.2
Delta ambulatory time before/after self-admin0.60.60.91.0-1.00.8-0.90.70.6-0.60.8-0.90.70.70.70.60.7-0.9
Time in closed arm before self-admin0.20.20.4-0.50.5-0.50.5-0.6-0.40.4-0.30.3-0.5-0.5-0.4-0.4-0.50.3
Time in closed arm after self-admin0.10.10.3-0.50.5-0.30.5-0.4-0.10.3-0.3-0.2-0.3-0.3-0.2-0.3-0.30.3
Time in open arm before self-admin0.80.91.8-0.80.8-0.80.8-0.5-1.01.3-1.20.7-0.7-0.7-1.2-1.3-0.71.0
Time in open arm after self-admin0.00.00.50.0-0.0-0.1-0.0-0.1-0.20.2-0.10.7-0.1-0.1-0.3-0.2-0.1-0.1
Sum of active levers in priming session hrs 5-62.82.84.11.8-1.81.7-1.81.51.5-1.51.6-2.01.61.61.61.51.6-1.6
Time to tail flick, vehicle, before self-admin0.90.91.90.7-0.60.9-0.70.41.4-1.11.1-0.61.11.11.11.11.1-0.9
Time to tail flick, vehicle, after self-admin2.02.12.81.6-1.61.4-1.61.01.5-1.61.6-0.51.51.51.71.61.5-1.4
Time to tail flick, test, before self-admin2.42.44.2-1.81.8-1.71.8-2.0-1.01.4-1.40.8-1.5-1.5-1.6-1.4-1.51.5
Time to tail flick, test, after self-admin3.73.84.9-2.02.0-2.12.0-2.2-1.71.9-2.01.9-1.9-1.9-1.9-1.9-1.92.0
Delta time to tail flick, vehicle, before/after SA0.90.91.11.0-1.10.9-1.10.80.8-1.01.00.10.90.91.01.00.9-1.0
Delta time to tail flick, test, before/after SA1.51.33.2-0.90.9-1.10.9-0.9-1.41.2-1.31.8-1.1-1.1-1.0-1.2-1.11.1
Ambulatory time before self-admin1.41.42.0-1.21.2-1.21.2-1.0-1.11.1-1.21.1-1.2-1.2-1.3-1.1-1.21.4
Ambulatory time after self-admin0.20.20.4-0.30.3-0.40.3-0.3-0.60.3-0.40.2-0.6-0.6-0.5-0.3-0.60.6
Total heroin consumption4.95.97.7-2.22.2-2.52.2-2.2-2.62.7-2.81.1-2.5-2.5-2.6-2.7-2.52.6
Area under the delay curve1.31.41.9-1.11.1-1.21.1-1.2-1.21.2-1.21.4-1.1-1.1-1.2-1.2-1.21.1
Delay disc. indifference point, 0s delay0.30.30.90.6-0.60.7-0.61.00.4-0.50.5-0.40.60.60.50.50.5-0.6
Delay disc. indifference point, 16s delay1.71.72.5-1.31.3-1.41.3-1.6-1.21.3-1.30.5-1.3-1.3-1.4-1.3-1.41.3
Delay disc. indifference point, 2s delay0.70.81.7-0.90.9-0.90.9-0.7-0.90.9-0.91.3-0.8-0.8-0.9-0.9-0.90.8
Delay disc. indifference point, 24s delay1.61.63.0-1.31.3-1.41.4-1.7-1.01.2-1.20.4-1.2-1.2-1.3-1.2-1.21.2
Delay disc. indifference point, 4s delay0.20.20.4-0.20.2-0.40.2-0.1-0.60.5-0.50.5-0.4-0.4-0.5-0.5-0.40.4
Delay disc. indifference point, 8s delay0.30.30.9-0.40.4-0.60.4-0.6-0.50.4-0.50.9-0.5-0.5-0.4-0.4-0.50.5
Delay discount exponential model param1.51.62.21.2-1.21.4-1.21.31.3-1.31.3-1.51.21.21.31.31.3-1.2
Delay discount hyperbolic model param1.11.21.81.0-1.01.1-1.01.01.1-1.11.1-1.31.01.01.11.11.1-1.0
Fecal boli incidents, locomotor time 11.31.42.01.1-1.11.2-1.10.81.4-1.21.2-0.71.21.21.31.21.3-1.3
Change in fecal boli incidents, locomotor task0.40.40.6-0.40.4-0.60.4-0.6-0.80.6-0.70.1-0.6-0.6-0.7-0.6-0.70.8
Time >=10cm from walls, locomotor time 10.00.00.2-0.00.10.10.0-0.10.3-0.20.2-0.40.20.20.20.20.2-0.2
Bouts of movement, locomotor time 10.10.10.3-0.30.40.10.3-0.00.40.00.1-0.50.10.20.0-0.00.1-0.3
Total resting periods, locomotor time 10.10.10.3-0.20.30.10.2-0.20.6-0.20.2-0.20.20.30.20.20.2-0.3
Rest time, locomotor task time 11.01.11.31.1-1.11.1-1.10.81.1-0.91.1-0.81.11.11.00.91.1-1.1
Distance moved, locomotor task time 10.91.02.0-0.80.8-0.80.8-0.1-1.41.0-1.11.4-1.0-1.0-1.0-1.0-1.01.1
Vertical activity count, locomotor time 11.11.24.5-1.00.9-1.00.9-0.4-1.40.9-1.02.1-1.0-1.1-0.9-0.9-1.11.0
Time >=10cm from walls, locomotor time 20.30.30.50.6-0.60.5-0.60.30.6-0.70.60.10.60.60.60.70.5-0.6
Bouts of movement, locomotor time 20.30.31.2-0.70.7-0.60.7-1.10.00.3-0.50.2-0.4-0.4-0.4-0.3-0.40.2
Total resting periods, locomotor time 20.20.20.9-0.60.6-0.50.6-0.90.10.2-0.30.1-0.3-0.3-0.2-0.2-0.30.0
Rest time, locomotor task time 20.10.10.6-0.30.3-0.30.3-0.70.10.1-0.1-0.8-0.2-0.2-0.1-0.1-0.10.3
Distance moved, locomotor task time 20.30.31.70.5-0.60.5-0.61.3-0.40.00.11.00.30.30.1-0.00.2-0.4
Vertical activity count, locomotor time 21.21.33.31.4-1.41.2-1.51.80.3-1.00.90.91.01.01.01.00.8-1.1
Weight adjusted by age1.61.85.71.0-0.91.2-0.90.71.6-1.51.5-2.41.21.21.21.51.2-1.3
Seeking ratio, delayed vs. immediate footshock0.80.91.7-0.91.0-0.91.0-1.3-0.51.3-1.0-0.4-0.6-0.8-1.1-1.3-0.80.8
Locomotion in novel chamber0.40.51.21.0-1.10.7-1.00.90.1-0.70.60.20.50.50.70.70.5-0.7
Locomotion in novel chamber post-restriction0.20.30.5-0.70.7-0.40.7-0.3-0.40.5-0.50.7-0.4-0.4-0.5-0.5-0.40.4
Progressive ratio0.10.10.40.3-0.30.4-0.30.40.4-0.20.3-0.60.30.50.30.20.3-0.4
Food seeking constrained by brief footshock0.30.40.7-0.80.8-0.50.8-0.7-0.20.8-0.60.2-0.3-0.4-0.6-0.8-0.50.4
Seeking ratio, punishment vs. effort0.70.80.9-1.00.9-1.00.9-1.0-0.80.9-0.90.9-0.7-0.9-0.9-0.9-0.80.9
Run reversals in cocaine runway, females0.10.10.30.0-0.1-0.3-0.0-0.1-0.50.2-0.3-0.00.0-0.4-0.2-0.2-0.00.4
Run reversals in cocaine runway, males0.50.41.10.8-0.80.7-0.81.10.3-0.60.6-0.50.60.60.60.60.6-0.6
Latency to leave start box in cocaine runway0.10.10.20.1-0.10.2-0.10.00.4-0.30.3-0.00.40.30.40.30.5-0.3
Latency to leave start box in cocaine runway, F0.10.10.30.1-0.10.2-0.10.10.4-0.30.30.10.50.30.40.30.5-0.3
Latency to leave start box in cocaine runway, M0.00.00.1-0.20.2-0.20.2-0.40.10.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.1
Cd content in liver1.61.82.21.5-1.51.4-1.51.41.1-1.51.4-1.11.31.31.11.51.3-1.3
Co content in liver0.60.81.51.1-1.20.9-1.21.20.3-0.80.70.00.80.80.70.80.8-0.7
Cu content in liver0.30.40.60.6-0.60.6-0.60.40.8-0.60.7-0.40.80.80.60.60.8-0.7
Fe content in liver0.40.50.90.6-0.50.5-0.50.10.9-0.70.9-0.80.70.70.70.70.7-0.9
K content in liver1.51.52.5-1.61.6-1.21.5-1.3-0.71.1-1.20.7-1.2-1.2-1.1-1.1-1.21.1
Mg content in liver0.80.82.0-1.41.4-0.81.4-1.2-0.10.8-0.70.5-0.7-0.7-0.7-0.8-0.70.7
Mn content in liver0.40.51.5-1.01.0-0.71.0-1.20.10.5-0.5-0.1-0.5-0.5-0.2-0.5-0.50.5
Na content in liver1.51.62.2-1.11.0-1.21.1-0.9-1.51.4-1.31.2-1.3-1.3-1.3-1.4-1.31.2
Rb content in liver0.50.71.2-0.90.9-0.90.9-1.1-0.51.0-0.8-0.0-0.9-0.9-0.9-1.0-0.90.4
Se content in liver1.11.31.61.3-1.31.1-1.31.11.0-1.10.9-1.01.11.11.21.11.1-1.2
Sr content in liver0.10.10.40.5-0.5-0.1-0.50.3-0.60.1-0.20.4-0.1-0.1-0.1-0.1-0.10.1
Zn content in liver0.10.10.6-0.60.6-0.40.6-0.80.3-0.20.10.5-0.2-0.20.00.2-0.20.2