Mob1b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000010996	0.02	0.01	7.2e-03	0	0	-0	-0	1.5e-01	1.2e-01	4.3e-01	4.1e-01
2	BLA	intron excision ratio	chr14:19337749:19340918	0.07	0.05	1.8e-03	0.04	0.03	0.02	0.04	2.1e-03	1.5e-02	2.5e-02	4.3e-03
3	Brain	mRNA stability	ENSRNOG00000010996	0.03	0.03	3.9e-03	0.04	0.01	0.01	0.02	1.2e-04	4.3e-02	6.5e-02	6.7e-03
4	Liver	gene expression	ENSRNOG00000010996	0.05	0.04	7.1e-03	0	0	0	0	2.1e-01	1.8e-01	9.8e-02	1.3e-01
5	PL	mRNA stability	ENSRNOG00000010996	0.04	0.03	5.5e-03	0.04	0.03	0	0.04	4.6e-04	2.1e-03	3.5e-01	7.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5
BMI with tail	2.5	8.0	12.4	2.7	-2.8	-2.0	3.5	-2.9
BMI without tail	0.4	0.8	1.5	0.3	-1.2	-0.7	1.1	-0.9
Body weight	0.1	0.3	0.9	0.3	-0.2	-0.9	0.6	0.2
Epididymis fat weight	0.2	0.4	0.5	-0.6	0.5	0.7	0.5	0.7
Glucose	1.0	1.5	2.1	-1.4	1.3	1.3	-0.7	1.4
Heart weight	0.3	0.4	0.8	0.9	-0.2	-0.9	0.3	-0.4
Left kidney weight	0.9	2.5	4.9	-1.5	1.5	0.4	-2.2	1.7
Right kidney weight	0.5	1.3	1.8	-1.3	1.2	0.1	-1.3	1.4
Tail length	0.9	2.7	5.7	-1.4	1.4	-0.0	-2.4	1.9
Length with tail	2.3	8.6	13.4	-2.8	3.3	1.5	-2.9	3.7
Length without tail	1.7	3.7	6.3	-1.6	2.5	1.7	-0.5	2.5
Liver weight, left	1.1	1.8	3.4	-1.6	1.3	1.2	-0.3	1.8
Liver weight, right	1.1	1.8	3.2	-1.8	1.2	1.6	-0.7	1.3
Parametrial fat weight	0.5	0.9	2.2	-1.5	0.1	1.0	-1.0	0.3
Retroperitoneal fat weight	0.4	1.4	2.9	-1.4	1.4	0.5	0.0	1.7
Intraocular pressure	0.9	1.2	4.6	0.9	-0.7	-2.2	0.2	0.3
Extensor digitorum longus weight	10.9	43.6	60.2	7.8	-7.2	-6.1	4.5	-7.0
Soleus weight	0.5	1.4	2.5	1.6	-1.5	0.0	0.7	-1.3
Tibialis anterior weight	3.9	13.3	19.1	4.4	-3.7	-3.0	3.5	-3.5
Tibia length	0.4	1.1	2.8	-0.7	1.7	0.8	0.0	1.3
Number of licking bursts	0.8	0.9	1.4	0.5	-1.1	-1.2	-1.2	-0.7
Food consumed during 24 hour testing period	0.9	1.1	2.2	-1.2	-0.1	1.1	-1.5	0.7
Times rat made contact with spout	0.8	0.9	2.7	-0.1	-1.7	-0.2	-0.3	-1.3
Mean time between licks in bursts	1.5	2.0	4.0	2.0	-0.3	-1.7	1.6	-0.7
Mean num. licks in bursts	0.6	0.7	1.7	-1.0	0.4	1.3	0.8	0.3
Std. dev. time between licks in bursts	0.2	0.2	0.3	0.5	0.4	-0.6	0.2	0.4
Water consumed over 24 hours	1.0	1.2	3.2	-1.2	-0.2	1.1	-1.8	0.1
Indifference point 0 sec	0.0	0.0	0.1	-0.2	0.3	-0.0	0.1	0.3
Indifference point AUC	1.6	1.9	3.6	-1.7	1.0	1.9	-0.5	1.2
Indifference point function ln k	0.7	0.9	1.6	1.0	-0.9	-1.2	-0.0	-1.3
Indifference point function log k	0.7	0.9	1.6	1.0	-0.9	-1.2	-0.0	-1.3
Delay discounting total patch changes 0 sec	0.0	0.0	0.0	-0.2	0.1	-0.0	0.1	0.1
Delay discounting total patch changes 12 sec	0.6	0.8	1.3	-0.5	0.8	1.0	1.0	1.1
Delay discounting total patch changes 18 sec	0.2	0.3	0.7	-0.1	-0.8	0.5	-0.1	-0.6
Delay discounting total patch changes 24 sec	0.9	1.1	1.8	-1.0	1.1	1.3	-0.0	1.2
Delay discounting total patch changes 6 sec	0.6	1.0	1.5	-1.2	0.8	1.2	-0.3	1.1
Delay discounting time to switch 0 sec	2.1	3.2	5.1	2.3	-1.7	-1.5	1.8	-1.6
Delay discounting water rate 0 sec	1.3	2.1	4.2	-1.8	1.1	0.8	-2.1	1.0
Delay discounting water rate 12 sec	0.6	0.9	3.3	-0.9	0.6	0.1	-1.8	0.4
Delay discounting water rate 18 sec	1.7	2.3	5.5	-1.6	0.9	1.0	-2.3	1.2
Delay discounting water rate 24 sec	1.6	2.3	7.8	-1.4	0.7	0.5	-2.8	1.0
Delay discounting water rate 6 sec	0.8	1.2	1.6	-1.2	1.3	0.7	-1.1	1.0
Locomotor activity	1.7	2.6	3.9	-1.2	1.8	1.2	-1.8	2.0
Locomotor testing distance	0.8	1.3	2.6	-0.5	1.0	1.0	-1.6	1.3
Locomotor testing rearing	0.3	0.5	1.5	-0.1	0.7	0.5	-1.2	0.6
Light reinforcement 1	0.3	0.6	1.1	-0.9	0.6	0.6	-0.4	1.1
Light reinforcement 2	0.1	0.1	0.2	0.2	-0.3	-0.3	0.1	0.5
Reaction time number correct	0.4	0.5	1.2	0.3	0.7	-0.9	-1.1	0.2
Reaction time mean minus median	0.6	0.7	2.5	0.7	-0.5	-1.6	0.3	-0.5
Reaction time mean minus median AUC	0.5	0.6	1.4	0.6	-0.2	-1.2	1.1	-0.4
Reaction time num false alarms	0.8	1.1	3.3	-0.0	0.4	1.3	1.8	0.6
Reaction time num false alarms AUC	0.8	1.1	4.2	0.4	0.1	0.9	2.0	0.4
Reaction time trials correct on left	0.4	0.5	1.2	0.3	0.7	-0.9	-1.1	0.2
Reaction time trials on left	0.4	0.6	1.2	0.4	0.7	-0.9	-1.1	0.2
Reaction time mean	0.4	0.5	1.0	0.5	-0.3	-0.9	1.0	-0.6
Reaction time mean AUC	0.2	0.3	1.0	0.3	-0.1	-0.6	1.0	-0.4
Median of all reaction times	0.3	0.5	1.4	0.4	-0.3	-0.6	1.2	-0.5
Reaction time omissions	0.7	0.9	2.5	1.2	0.1	-1.6	0.5	-0.3
Reaction time false alarm rate	1.1	1.6	5.7	0.1	-0.0	1.5	2.4	0.4
Reaction time premature initiation rate	0.5	0.7	1.7	-1.0	0.3	1.3	0.3	0.8
Reaction time premature initiations	0.5	0.7	1.1	-0.9	0.8	1.0	-0.3	1.0
Std. dev. reaction times	0.2	0.3	1.1	0.4	-0.0	-1.1	0.5	-0.1
Reaction time trials completed	0.4	0.6	1.2	0.4	0.7	-0.9	-1.1	0.2
Reaction time trials AUC	0.4	0.5	1.1	0.5	0.6	-1.0	-1.1	0.1
Social response proportion	0.6	0.7	1.9	-1.4	0.0	1.2	-0.3	0.0
Social responses	0.5	0.7	2.0	-0.9	0.4	1.4	0.1	0.6
Social time	0.2	0.3	0.6	-0.7	0.4	0.1	-0.4	0.8
Conditioned locomotion	0.8	0.9	1.8	0.1	1.4	0.7	1.0	1.1
Cocaine response after cond. corrected	0.6	0.7	1.2	-0.8	1.1	0.6	-0.8	0.9
Cocaine response after cond. not corrected	0.4	0.4	1.5	-0.5	0.5	0.3	-1.2	0.1
Cocaine response before conditioning	1.2	1.4	3.0	0.8	-1.6	-0.7	-0.7	-1.7
Saline control response	0.4	0.5	0.9	-0.9	0.5	0.9	-0.3	0.7
Condit. Reinf. active minus inactive responses	0.3	0.3	0.9	0.1	0.9	-0.1	0.4	0.8
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.2	0.3	-0.0	-0.4	0.1	-0.2
Condit. Reinf. active responses	0.6	0.9	2.1	-0.4	1.5	0.4	-0.1	1.4
Condit. Reinf. inactive responses	1.4	1.7	2.7	-1.1	1.5	1.3	-0.8	1.7
Condit. Reinf. lever presses	1.5	2.1	5.0	-0.7	2.2	0.4	-0.9	2.0
Condit. Reinf. lever reinforcers received	0.8	1.2	2.7	-0.5	1.6	0.6	-0.2	1.6
Pavlov. Cond. lever latency	0.3	0.5	0.7	-0.1	-0.7	0.8	0.7	-0.7
Pavlov. Cond. magazine entry latency	0.7	0.8	2.7	0.9	0.5	-1.7	-0.6	0.3
Pavlov. Cond. change in total contacts	0.3	0.4	1.1	0.5	0.5	-1.1	-0.5	0.6
Pavlov. Cond. index score	0.7	0.9	2.4	0.6	0.7	-1.6	-0.9	0.6
Pavlov. Cond. latency score	0.6	0.8	2.5	0.8	0.4	-1.6	-0.8	0.3
Pavlov. Cond. lever contacts	0.7	0.9	1.4	0.0	1.2	-0.9	-1.0	1.1
Pavlov. Cond. magazine entry number	1.0	1.2	4.2	-1.1	0.1	2.0	0.8	-0.0
Pavlov. Cond. intertrial magazine entries	0.6	0.8	2.0	-1.0	0.5	1.4	0.4	0.6
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.9	2.3	0.5	0.8	-1.5	-0.9	0.7
Pavlov. Cond. response bias	0.8	1.1	2.3	0.5	0.9	-1.5	-1.0	1.0
Conditioned reinforcement - actives	0.6	0.6	1.4	-0.5	0.8	0.9	-0.1	1.2
Conditioned reinforcement - inactives	2.1	2.4	5.1	-1.9	1.0	2.3	-0.9	1.3
Conditioned locomotion	1.1	1.3	2.9	-0.9	1.2	0.4	-1.2	1.7
Intermittent access intake day 1-15 change	0.3	0.3	0.8	0.4	-0.3	-0.9	-0.4	-0.0
Intermittent access intake escalation	0.1	0.1	0.3	-0.1	0.2	-0.2	-0.5	0.4
Intermittent access intake escalation 2	2.5	2.5	3.1	-1.8	1.5	1.1	-1.6	1.8
Intermitt. access day 1 inactive lever presses	1.6	1.8	5.9	-1.0	0.5	2.4	1.2	0.5
Intermitt. access day 15 inactive lever presses	1.0	1.1	2.6	-1.4	-0.3	1.6	-1.0	0.0
Intermitt. access escalation Index	4.4	4.0	5.9	2.0	-2.1	-2.3	0.4	-2.4
Intermittent access day 1 total infusions	0.6	0.6	1.1	-0.6	0.9	0.7	-0.6	1.1
Intermittent access day 15 total infusions	1.4	1.6	3.1	-1.1	1.4	0.8	-1.1	1.8
Intermittent access terminal intake (last 3 days)	2.7	3.0	4.3	-1.7	1.8	1.4	-1.7	2.1
Intermittent access total infusions	0.8	0.9	1.8	-0.8	1.0	0.7	-0.8	1.3
Intermittent access day 1 locomotion	0.3	0.3	0.7	-0.5	0.4	0.8	-0.1	0.6
Intermittent access day 15 total locomotion	2.7	2.8	5.7	-1.4	1.9	1.1	-1.2	2.4
Intermittent access total locomotion	0.6	0.7	1.7	-0.6	0.9	0.5	-0.4	1.3
Intermittent access standard deviation	1.2	1.3	2.3	-1.0	1.2	0.8	-1.0	1.5
Cocaine induced anxiety	0.3	0.4	1.0	0.5	-0.4	-1.0	-0.1	-0.7
Post-drug Anxiety	0.4	0.4	1.1	-0.5	1.0	0.2	0.3	0.8
Baseline Anxiety	0.8	0.8	1.0	-0.8	0.9	1.0	-0.7	1.0
Lifetime Intake	0.4	0.4	1.1	-0.5	0.7	0.3	-0.5	1.1
Incentive Sensitization - Responses	0.5	0.5	0.8	-0.4	0.9	0.6	0.7	0.9
Incentive Sensitization - Breakpoint	0.6	0.6	1.0	-0.5	1.0	0.7	0.5	1.0
Progressive ratio test 1 active lever presses	1.5	1.6	2.8	-1.0	1.7	0.5	-1.0	1.7
Progressive ratio test 1 breakpoint	1.2	1.2	2.3	-0.8	1.5	0.3	-0.9	1.5
Progressive ratio test 1 inactive lever presses	2.4	2.6	6.9	-1.6	1.2	2.6	0.4	1.3
Progressive ratio test 2 active lever presses	2.2	2.3	4.3	-1.2	2.0	1.2	-0.1	2.1
Progressive ratio test 2 breakpoint	1.4	1.5	3.1	-0.9	1.8	0.9	0.1	1.7
Progressive ratio test 2 inactive lever presses	3.1	3.6	5.1	-1.8	2.2	2.1	-0.7	2.3
Total sessions with >9 infusions	1.0	1.1	1.9	1.1	-1.2	-1.4	-0.2	-0.8
Short access day 1 total inactive lever presses	1.6	1.7	3.5	-1.2	1.3	1.9	-0.6	1.4
Short access day 10 total inactive lever presses	0.6	0.6	1.9	-0.8	0.2	1.4	-0.7	0.0
Short access day 1 total infusions	0.0	0.0	0.2	-0.2	0.1	0.1	-0.0	0.4
Short access day 10 total infusions	0.2	0.2	0.5	-0.1	0.3	0.0	-0.5	0.7
Short access total infusions	0.1	0.1	0.2	0.4	-0.3	-0.5	0.2	0.1
Short access day 1 locomotion	0.2	0.2	0.7	-0.4	0.0	-0.4	-0.9	0.4
Short access day 10 total locomotion	0.4	0.4	1.8	0.1	-0.1	0.2	1.3	-0.3
Short access total locomotion	0.2	0.2	0.4	0.4	-0.6	-0.5	0.4	-0.4
Compulsive drug intake	1.2	1.2	1.9	1.0	-1.4	-0.9	1.1	-1.2
One hour access (0.3 mA shock)	2.8	3.3	6.2	-1.5	2.0	0.3	-1.9	2.5
One hour access (shock baseline)	2.8	3.3	6.1	-1.6	2.2	1.0	-1.3	2.5
Number of responses in last shaping day	0.5	0.5	0.9	0.7	-0.9	-0.6	1.0	-0.3
Context. condit. distance diff. score	1.2	1.4	3.2	-0.8	1.2	1.8	-0.7	1.2
Locomotion velocity, session 1	0.5	0.5	1.5	0.6	-0.1	-0.9	1.2	-0.0
Locomotion distance, session 1	0.3	0.4	1.0	-0.7	0.7	0.4	-0.3	1.0
Locomotion velocity, session 2	0.7	0.8	1.7	-0.7	1.1	0.6	-0.5	1.3
Locomotion distance, session 2	0.5	0.7	1.7	-0.7	0.9	0.4	-0.5	1.3
Locomotion velocity, session 3	0.5	0.6	1.1	-1.0	0.7	0.6	-0.3	1.0
Locomotion distance, session 3	0.1	0.1	0.3	-0.3	-0.0	-0.1	-0.0	0.6
Stereotopy head waving bouts, day 3	0.1	0.1	0.5	0.3	0.0	-0.7	0.3	-0.0
Stereotopy head waving duration, day 3	0.1	0.1	0.2	0.1	0.4	-0.4	-0.1	0.1
Locomotion velocity, session 7	0.9	1.0	2.0	-1.4	1.0	1.0	-0.6	0.7
Locomotion distance, session 7	0.6	0.7	1.4	-1.2	0.4	0.9	-0.5	1.0
Stereotopy head waving bouts, day 7	0.4	0.5	1.1	0.5	-0.9	-0.5	-0.1	-1.0
Stereotopy head waving duration, day 7	0.4	0.5	1.1	0.5	-0.6	-0.0	1.0	-0.8
Locomotion velocity, session 8	0.4	0.4	1.3	-0.3	0.4	1.1	0.5	0.7
Locomotion distance, session 8	1.2	1.8	3.5	-1.3	1.0	1.9	-1.0	1.4
Degree of sensitization distance	0.6	0.6	1.8	-0.8	0.5	1.3	-0.4	0.3
Degree of sensitization stereotypy	0.2	0.2	0.5	0.3	-0.6	-0.3	0.1	-0.7
Condit. Reinf. active minus inactive responses	0.6	0.6	1.0	0.9	-0.6	-1.0	0.7	-0.8
Condit. Reinf. active-inactive response ratio	2.7	2.9	4.2	2.0	-1.6	-1.8	0.7	-2.0
Condit. Reinf. active responses	0.0	0.0	0.2	-0.0	0.1	-0.4	-0.2	0.1
Condit. Reinf. inactive responses	1.1	1.3	2.0	-1.4	0.9	0.7	-1.2	1.2
Incentive salience index mean	0.1	0.2	0.2	0.4	-0.4	-0.2	0.5	-0.4
Condit. Reinf. lever presses	0.0	0.0	0.1	0.1	-0.3	0.1	0.1	-0.1
Time in familiar zone, hab. session 1	0.2	0.2	0.4	-0.1	0.3	0.5	0.0	0.6
Time in novel zone, hab. session 1	0.2	0.2	0.5	0.2	-0.0	-0.5	0.7	-0.4
Total zone transitions, hab. session 1	0.7	1.1	3.3	-0.7	1.1	0.1	-0.6	1.8
Total locomotion distance, hab. session 1	2.8	4.0	6.7	-2.0	2.1	1.3	-1.8	2.6
Locomotion velocity, hab. session 1	2.1	3.0	4.8	-1.8	1.6	1.0	-1.9	2.2
Time in familiar zone, hab. session 2	0.3	0.3	0.6	0.7	-0.7	-0.5	0.3	-0.4
Time in novel zone, hab. session 2	0.3	0.3	0.4	-0.4	0.6	0.7	0.6	-0.2
Total zone transitions, hab. session 2	0.3	0.4	1.6	0.1	0.1	-0.5	-1.3	-0.2
Total locomotion distance, hab. session 2	0.7	1.0	3.3	-0.7	0.9	0.2	-1.8	0.4
Locomotion velocity, hab. session 2	0.9	1.2	3.4	-0.8	1.1	0.2	-1.8	0.7
Novel to familiar place preference ratio	0.1	0.1	0.3	-0.2	0.3	-0.2	0.5	0.1
Novelty place preference	0.1	0.2	0.5	-0.0	0.4	-0.4	0.7	0.1
Time in novel zone, NPP test	0.2	0.2	0.4	-0.3	0.7	-0.1	0.7	0.3
Total zone transitions, NPP test	0.1	0.1	0.3	0.1	-0.0	-0.6	-0.2	-0.0
Total locomotion distance, NPP test	0.4	0.6	2.0	-0.4	0.5	-0.5	-1.4	0.6
Locomotion velocity, NPP test	0.3	0.4	1.4	-0.0	0.3	-0.8	-1.2	0.3
Pavlov. Cond. lever latency	1.1	1.4	2.9	1.3	-1.0	-1.7	-0.2	-1.3
Pavlov. Cond. magazine entry latency	0.1	0.2	0.3	-0.1	0.4	0.6	0.0	0.5
Pavlov. Cond. change in total contacts	0.4	0.4	0.6	-0.4	0.5	0.8	0.7	0.6
Pavlov. Cond. index score	0.7	0.9	1.8	-0.7	0.8	1.3	0.6	1.0
Pavlov. Cond. latency score	0.7	0.9	2.1	-0.8	0.8	1.4	0.5	1.0
Pavlov. Cond. lever contacts	1.2	1.4	2.6	-1.3	1.1	1.6	0.0	1.3
Pavlov. Cond. magazine entry number	0.1	0.1	0.2	-0.0	-0.1	-0.4	-0.5	-0.3
Pavlov. Cond. intertrial magazine entries	0.7	0.8	1.8	-0.9	1.3	0.2	0.0	1.2
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.9	1.9	-0.8	0.8	1.4	0.5	1.1
Pavlov. Cond. response bias	0.8	1.0	1.6	-0.9	1.0	1.2	0.1	1.3
Bone: apparent density	0.8	1.4	3.1	0.9	-1.2	-1.8	-0.3	-1.2
Bone surface	0.7	1.2	2.5	0.7	-0.8	-1.1	-1.6	-1.1
Bone volume	0.2	0.4	1.2	0.0	-0.1	-0.6	-1.1	-0.5
Bone: connectivity density	1.4	2.2	3.9	1.5	-1.6	-2.0	-0.0	-1.5
Bone: cortical apparent density	0.5	0.7	2.8	0.0	-0.8	-0.1	1.7	-0.4
Bone: cortical area	0.2	0.3	0.7	0.2	-0.7	-0.1	-0.5	-0.9
Bone: cortical porosity	0.9	1.0	2.0	1.3	-0.7	-1.4	0.1	-1.0
Bone: cortical porosity	1.7	1.9	3.0	1.6	-1.1	-1.7	0.4	-1.5
Bone: cortical thickness	1.4	2.3	3.9	1.6	-1.8	-1.1	0.7	-2.0
Bone: cortical thickness	0.5	0.6	2.8	-0.2	-0.2	-0.3	-1.7	-0.3
Bone: cortical tissue density	0.6	0.8	3.0	0.1	-0.8	-0.1	1.7	-0.4
Bone: elastic displacement	0.5	0.6	0.9	0.9	-0.8	-0.6	-0.5	-0.9
Bone: elastic work	1.1	1.5	1.9	1.3	-1.4	-1.2	-0.9	-1.2
Bone: endosteal estimation	2.1	4.4	5.8	-2.4	2.0	2.0	-2.1	2.0
Bone: endosteal perimeter	0.5	1.0	2.5	-0.6	1.1	0.1	-1.6	0.9
Bone: final force	0.2	0.4	1.0	-0.0	-0.1	-0.9	-1.0	-0.3
Bone: final moment	0.3	0.5	1.5	-0.1	0.1	-0.9	-1.2	-0.2
Bone: marrow area	2.0	4.2	5.5	-2.3	1.9	2.0	-2.0	1.9
Bone: maximum diameter	0.2	0.3	0.9	0.6	-0.4	-0.6	0.1	-0.9
Bone: maximum force	0.4	0.7	2.6	-0.3	-0.1	-0.7	-1.6	-0.3
Bone: maximum moment	0.5	0.8	3.4	-0.4	0.1	-0.7	-1.8	-0.1
Bone: minimum diameter	4.3	8.0	10.7	-3.3	3.0	2.0	-2.9	2.8
Bone: periosteal estimation	0.5	1.1	2.0	-1.1	0.8	1.0	-1.4	0.6
Bone: periosteal perimeter	0.2	0.3	1.3	-0.0	0.2	-0.3	-1.2	-0.1
Bone: post-yield work	0.3	0.4	0.8	-0.9	0.6	0.1	-0.7	0.6
Bone: stiffness	0.6	0.9	1.4	-1.2	1.2	-0.0	-0.9	1.0
Bone: tissue strength	0.5	0.5	0.8	-0.8	0.9	-0.0	-0.7	0.7
Bone: trabecular number	0.6	0.9	2.3	0.6	-1.0	-1.5	-0.0	-0.8
Bone: trabecular spacing	0.7	1.0	3.0	-0.1	0.6	1.1	1.7	0.4
Bone: trabecular thickness	0.4	0.4	1.6	-0.4	-0.0	-0.6	-1.2	0.1
Bone: trabecular tissue density	0.5	0.7	1.3	0.7	-0.6	-1.1	0.9	-0.6
Breakpoint value in progressive ratio session	0.0	0.0	0.1	-0.1	-0.2	0.0	0.4	-0.0
Distance traveled before self-admin	0.7	0.8	1.1	-0.8	1.1	0.9	-0.3	1.0
Distance traveled after self-admin	4.5	5.0	5.7	-2.2	2.4	2.1	-2.2	2.2
Delta time in closed arm before/after self-admin	0.7	0.7	0.8	0.8	-0.8	-0.8	0.7	-0.9
Delta time in open arm before/after self-admin	1.6	1.5	3.3	-1.0	1.8	1.0	-0.2	1.5
Diff in mean of infusions in LGA sessions	0.5	0.6	1.0	0.6	-0.8	-0.1	1.0	-0.8
Extinction: sum of active levers before priming	0.2	0.2	0.4	-0.6	0.3	0.4	-0.7	0.4
Active lever presses in extinction session 6	0.5	0.5	1.5	-0.8	0.0	0.2	-1.2	0.3
Delta distance traveled before/after self-admin	0.6	0.7	1.7	-0.8	0.7	0.7	-1.3	0.4
Delta ambulatory time before/after self-admin	0.2	0.3	1.0	-0.4	0.1	0.3	-1.0	-0.0
Time in closed arm before self-admin	0.8	0.9	2.1	-1.0	1.0	1.4	-0.2	0.7
Time in closed arm after self-admin	0.6	0.6	1.4	-0.4	1.2	0.8	-0.0	0.9
Time in open arm before self-admin	1.4	1.5	3.3	1.0	-1.8	-1.3	-0.3	-1.2
Time in open arm after self-admin	0.2	0.2	0.4	-0.5	0.4	0.3	0.2	0.6
Sum of active levers in priming session hrs 5-6	0.3	0.3	0.7	-0.6	0.4	0.8	-0.1	0.6
Time to tail flick, vehicle, before self-admin	0.7	0.7	1.6	-1.0	0.6	0.4	-1.3	0.8
Time to tail flick, vehicle, after self-admin	2.2	2.3	4.0	-1.3	1.6	1.4	-1.2	2.0
Time to tail flick, test, before self-admin	0.2	0.2	0.5	0.1	0.1	0.5	0.7	-0.1
Time to tail flick, test, after self-admin	3.1	3.2	4.3	-2.1	1.7	1.8	-1.3	2.1
Delta time to tail flick, vehicle, before/after SA	0.5	0.5	0.9	-0.6	0.7	1.0	0.2	1.0
Delta time to tail flick, test, before/after SA	2.2	2.0	3.7	-1.6	1.4	1.2	-0.7	1.9
Ambulatory time before self-admin	1.3	1.4	2.1	-1.2	1.4	1.2	-0.3	1.5
Ambulatory time after self-admin	4.4	4.9	5.8	-2.1	2.4	1.8	-2.3	2.4
Total heroin consumption	1.3	1.6	3.5	-1.4	0.8	0.9	-1.9	1.0
Area under the delay curve	0.8	0.8	1.9	-0.3	1.3	-0.3	0.5	1.4
Delay disc. indifference point, 0s delay	0.3	0.3	0.7	-0.1	0.8	-0.2	0.1	0.9
Delay disc. indifference point, 16s delay	0.8	0.9	2.8	0.5	0.9	-0.4	1.7	0.6
Delay disc. indifference point, 2s delay	3.2	3.5	5.6	-2.2	2.0	1.5	-1.0	2.4
Delay disc. indifference point, 24s delay	0.2	0.2	0.5	0.1	0.6	0.1	0.4	0.7
Delay disc. indifference point, 4s delay	1.5	1.6	3.8	-1.0	1.8	0.1	0.0	2.0
Delay disc. indifference point, 8s delay	1.0	1.0	2.4	1.0	-0.2	-1.5	1.3	-0.1
Delay discount exponential model param	0.8	0.9	2.1	0.4	-1.4	0.2	-0.5	-1.4
Delay discount hyperbolic model param	1.3	1.3	3.2	0.7	-1.7	-0.1	-0.3	-1.8
Fecal boli incidents, locomotor time 1	0.5	0.6	1.2	0.9	0.1	-1.1	-0.6	-0.6
Change in fecal boli incidents, locomotor task	0.5	0.5	1.5	0.2	-0.7	-1.2	-0.0	-0.5
Time >=10cm from walls, locomotor time 1	1.4	1.4	5.6	1.0	-0.6	-2.4	0.1	-0.2
Bouts of movement, locomotor time 1	0.5	0.6	1.4	0.7	-0.5	-1.2	0.5	-0.7
Total resting periods, locomotor time 1	0.4	0.4	1.2	0.6	-0.4	-1.1	0.2	-0.7
Rest time, locomotor task time 1	1.4	1.5	6.5	-0.8	0.6	-0.2	-2.5	0.4
Distance moved, locomotor task time 1	0.2	0.3	1.0	0.4	-0.4	0.2	1.0	0.3
Vertical activity count, locomotor time 1	0.7	0.7	2.3	-0.3	0.3	0.8	1.5	0.5
Time >=10cm from walls, locomotor time 2	1.1	1.1	4.9	0.5	-0.2	-2.2	-0.7	-0.1
Bouts of movement, locomotor time 2	0.5	0.5	1.0	-1.0	0.5	1.0	-0.6	0.2
Total resting periods, locomotor time 2	0.4	0.4	0.9	-0.9	0.3	0.8	-0.6	0.1
Rest time, locomotor task time 2	0.9	1.0	3.3	-0.9	0.8	0.3	-1.8	0.5
Distance moved, locomotor task time 2	1.9	2.2	3.6	1.9	-1.3	-1.6	1.5	-1.0
Vertical activity count, locomotor time 2	0.4	0.4	1.0	0.5	0.1	-1.0	0.9	0.3
Weight adjusted by age	0.6	0.7	1.6	0.8	-1.3	-0.7	-0.4	-0.6
Seeking ratio, delayed vs. immediate footshock	0.7	0.8	1.8	-0.8	1.0	1.3	-0.6	0.5
Locomotion in novel chamber	0.1	0.1	0.2	0.2	0.4	0.1	0.5	0.4
Locomotion in novel chamber post-restriction	0.9	1.1	2.0	-1.4	1.2	-0.1	-0.5	1.4
Progressive ratio	0.6	0.7	1.8	1.3	-0.8	-0.4	0.6	-0.9
Food seeking constrained by brief footshock	0.3	0.3	1.0	0.5	-0.6	-1.0	-0.0	-0.3
Seeking ratio, punishment vs. effort	0.3	0.4	1.3	-1.1	0.4	0.1	-0.3	0.6
Run reversals in cocaine runway, females	1.8	1.8	3.7	-1.5	0.4	1.6	-1.9	0.6
Run reversals in cocaine runway, males	0.4	0.4	1.0	0.6	-1.0	0.3	0.5	-0.5
Latency to leave start box in cocaine runway	0.7	0.8	2.1	-1.2	0.3	0.3	-1.4	0.1
Latency to leave start box in cocaine runway, F	2.1	2.3	4.4	-2.1	1.2	1.3	-1.6	1.2
Latency to leave start box in cocaine runway, M	2.0	1.9	3.5	0.9	-1.7	-1.4	-0.7	-1.9
Cd content in liver	1.9	2.0	2.6	1.6	-1.5	-1.3	1.1	-1.6
Co content in liver	0.2	0.3	1.0	-0.3	0.2	-0.1	-1.0	0.6
Cu content in liver	1.2	1.4	3.4	-1.0	1.8	1.1	-0.1	1.3
Fe content in liver	0.1	0.2	0.4	0.3	-0.3	-0.7	0.4	0.1
K content in liver	2.6	2.6	4.8	-1.7	1.4	2.2	0.9	1.5
Mg content in liver	2.9	3.0	4.2	-1.7	1.8	2.0	0.8	2.1
Mn content in liver	0.3	0.4	1.0	-0.4	0.5	1.0	0.5	0.5
Na content in liver	0.7	0.8	1.4	-1.1	1.2	0.2	-0.3	1.1
Rb content in liver	0.3	0.4	0.9	0.6	-0.4	-0.9	0.6	-0.6
Se content in liver	1.2	1.5	3.2	-0.7	1.5	1.0	0.8	1.8
Sr content in liver	0.5	0.5	1.0	0.6	-0.9	-0.1	-0.6	-1.0
Zn content in liver	0.9	1.0	1.8	-0.8	0.9	1.3	0.4	1.3