Hub : Genes

Fabp4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000010805 0.19 0.13 1.5e-11 0.09 0.1 0.1 0.09 3.4e-10 7.6e-11 4.3e-11 2.7e-10
2 Adipose mRNA stability ENSRNOG00000010805 0.05 0.03 3.9e-05 0.03 0.02 0.02 0.02 3.2e-04 9.4e-04 3.4e-03 1.6e-03
3 BLA gene expression ENSRNOG00000010805 0.41 0.15 0.0e+00 0.22 0.22 0.21 0.24 1.0e-11 3.1e-12 2.6e-11 2.8e-13
4 Brain gene expression ENSRNOG00000010805 0.18 0.1 7.3e-13 0.1 0.09 0.1 0.1 6.0e-10 4.5e-09 9.6e-10 1.6e-09
5 IL gene expression ENSRNOG00000010805 0.76 0.15 1.1e-07 0.17 0.1 0.17 0.17 5.8e-05 2.6e-03 5.7e-05 8.1e-05
6 NAcc gene expression ENSRNOG00000010805 0.1 0.06 5.4e-06 0.03 0.02 0.02 0.03 4.8e-03 6.0e-03 1.1e-02 4.4e-03
7 OFC gene expression ENSRNOG00000010805 0.43 0.17 2.8e-05 0.08 0.05 0.03 0.03 7.4e-03 2.5e-02 5.9e-02 8.2e-02
8 PL gene expression ENSRNOG00000010805 0.57 0.18 0.0e+00 0.27 0.22 0.27 0.27 1.4e-20 2.8e-16 6.5e-21 1.9e-20

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail2.06.58.4-1.92.52.92.92.52.62.62.4
BMI without tail5.110.712.8-1.63.23.63.53.43.43.63.4
Body weight0.73.03.5-1.91.81.71.71.61.61.81.9
Epididymis fat weight0.10.21.71.30.20.0-0.20.2-0.2-0.00.3
Glucose1.52.32.8-0.71.51.71.61.51.61.61.6
Heart weight1.72.53.40.9-1.4-1.9-1.7-1.5-1.6-1.8-1.6
Left kidney weight1.03.04.51.4-2.1-1.8-1.7-1.6-1.7-1.8-1.6
Right kidney weight0.51.42.91.7-1.3-1.2-1.1-0.9-1.1-1.1-0.9
Tail length0.51.63.4-0.41.21.11.01.31.31.41.8
Length with tail0.00.10.3-0.50.1-0.4-0.4-0.0-0.1-0.00.4
Length without tail0.81.72.6-0.5-1.0-1.6-1.5-1.3-1.5-1.4-1.3
Liver weight, left1.62.63.6-1.11.81.81.91.51.61.61.3
Liver weight, right0.20.40.60.60.60.80.80.60.60.60.5
Parametrial fat weight0.30.51.10.40.80.50.40.80.80.71.0
Retroperitoneal fat weight0.00.10.10.30.1-0.3-0.3-0.1-0.3-0.3-0.1
Intraocular pressure2.33.34.4-1.52.11.81.81.71.81.91.9
Extensor digitorum longus weight10.240.848.4-2.66.96.46.46.96.96.87.0
Soleus weight0.82.42.9-0.71.51.71.71.51.71.61.6
Tibialis anterior weight8.027.832.1-3.05.75.45.45.55.55.75.5
Tibia length1.33.84.70.8-1.9-2.0-2.2-2.0-2.1-2.1-2.1
Number of licking bursts0.40.50.7-0.3-0.7-0.7-0.7-0.8-0.7-0.7-0.8
Food consumed during 24 hour testing period2.02.43.1-0.91.71.61.61.61.61.81.5
Times rat made contact with spout0.10.10.30.2-0.6-0.2-0.2-0.4-0.2-0.3-0.3
Mean time between licks in bursts1.01.53.0-1.71.31.01.11.11.11.21.0
Mean num. licks in bursts0.20.20.40.40.30.50.50.40.50.50.6
Std. dev. time between licks in bursts0.10.10.7-0.90.1-0.2-0.10.0-0.10.0-0.1
Water consumed over 24 hours0.10.10.2-0.20.30.40.40.30.40.40.3
Indifference point 0 sec0.91.51.91.2-1.4-1.0-1.3-1.2-1.2-1.3-1.1
Indifference point AUC0.50.60.80.80.60.80.90.80.80.80.8
Indifference point function ln k0.00.00.10.10.30.0-0.10.30.20.20.3
Indifference point function log k0.00.00.10.10.30.0-0.10.30.20.20.3
Delay discounting total patch changes 0 sec0.50.91.91.4-1.0-0.7-0.9-0.8-0.8-0.9-0.8
Delay discounting total patch changes 12 sec0.50.62.01.4-0.9-0.7-0.6-0.6-0.5-0.7-0.5
Delay discounting total patch changes 18 sec0.50.61.20.70.51.10.90.70.70.70.8
Delay discounting total patch changes 24 sec0.20.31.71.3-0.4-0.3-0.4-0.2-0.2-0.30.1
Delay discounting total patch changes 6 sec0.10.21.31.10.10.10.10.20.20.20.2
Delay discounting time to switch 0 sec1.72.65.3-2.31.51.61.41.41.51.61.4
Delay discounting water rate 0 sec0.30.42.51.6-0.4-0.3-0.3-0.3-0.3-0.3-0.3
Delay discounting water rate 12 sec1.42.12.80.9-1.7-1.4-1.4-1.6-1.6-1.6-1.4
Delay discounting water rate 18 sec0.50.70.90.2-0.8-0.9-0.8-1.0-0.9-0.9-0.8
Delay discounting water rate 24 sec0.20.21.71.3-0.1-0.2-0.2-0.1-0.3-0.2-0.1
Delay discounting water rate 6 sec2.13.14.00.9-1.8-1.8-1.8-1.9-2.0-2.0-1.8
Locomotor activity0.00.00.00.1-0.1-0.1-0.00.1-0.10.1-0.0
Locomotor testing distance0.00.00.0-0.0-0.1-0.1-0.1-0.0-0.00.1-0.0
Locomotor testing rearing0.81.31.70.7-1.3-1.1-1.1-1.2-1.1-1.2-1.3
Light reinforcement 10.91.62.40.81.11.61.41.41.21.11.4
Light reinforcement 22.63.44.7-0.31.82.02.22.02.01.81.9
Reaction time number correct0.40.61.7-1.3-0.5-0.5-0.6-0.9-0.7-0.6-0.5
Reaction time mean minus median2.83.64.90.71.72.12.02.12.21.91.9
Reaction time mean minus median AUC3.54.56.10.11.92.52.32.32.42.22.2
Reaction time num false alarms1.11.52.6-1.6-1.2-1.0-1.1-1.3-1.2-1.0-1.3
Reaction time num false alarms AUC1.01.41.7-1.3-1.2-1.1-1.1-1.3-1.2-1.0-1.3
Reaction time trials correct on left0.40.61.7-1.3-0.5-0.5-0.6-0.9-0.7-0.6-0.5
Reaction time trials on left0.30.51.8-1.3-0.4-0.4-0.5-0.8-0.6-0.5-0.4
Reaction time mean2.02.84.3-0.41.62.11.81.81.81.71.6
Reaction time mean AUC2.33.04.7-0.61.62.21.91.81.91.81.7
Median of all reaction times1.72.23.6-0.91.51.91.61.51.51.51.3
Reaction time omissions4.35.97.70.12.42.82.72.62.72.62.3
Reaction time false alarm rate0.20.20.5-0.1-0.6-0.5-0.5-0.4-0.5-0.4-0.7
Reaction time premature initiation rate1.72.22.81.5-1.4-1.6-1.5-1.5-1.4-1.7-1.4
Reaction time premature initiations1.62.33.20.8-1.5-1.6-1.6-1.7-1.6-1.8-1.4
Std. dev. reaction times1.72.43.50.51.41.91.61.71.81.51.5
Reaction time trials completed0.30.51.8-1.3-0.4-0.4-0.5-0.8-0.6-0.5-0.4
Reaction time trials AUC0.30.42.2-1.5-0.3-0.3-0.4-0.6-0.5-0.4-0.2
Social response proportion0.30.30.50.60.50.50.40.50.70.60.5
Social responses0.70.91.30.80.91.11.00.91.01.00.9
Social time0.00.00.1-0.2-0.20.10.0-0.30.0-0.1-0.2
Conditioned locomotion0.20.20.3-0.20.50.60.50.50.50.50.5
Cocaine response after cond. corrected0.91.01.20.5-1.1-1.0-1.1-1.1-1.0-1.1-1.0
Cocaine response after cond. not corrected1.61.82.40.6-1.5-1.3-1.4-1.5-1.4-1.4-1.4
Cocaine response before conditioning0.20.30.5-0.3-0.7-0.4-0.4-0.7-0.6-0.6-0.6
Saline control response1.01.31.9-1.4-1.0-1.0-1.1-1.2-1.2-1.0-1.2
Condit. Reinf. active minus inactive responses2.32.84.1-2.0-1.6-1.5-1.4-1.8-1.7-1.5-1.8
Condit. Reinf. active-inactive response ratio1.31.33.1-1.7-1.1-0.8-0.8-1.3-1.1-0.9-1.2
Condit. Reinf. active responses3.04.15.1-2.1-2.0-1.8-1.9-2.2-2.1-1.8-2.2
Condit. Reinf. inactive responses0.20.30.4-0.6-0.4-0.5-0.6-0.5-0.5-0.4-0.6
Condit. Reinf. lever presses1.21.72.2-1.5-1.3-1.0-1.1-1.4-1.3-1.2-1.5
Condit. Reinf. lever reinforcers received3.24.65.9-2.1-2.1-1.9-2.0-2.4-2.2-2.0-2.4
Pavlov. Cond. lever latency1.31.72.1-0.11.41.21.41.41.41.41.5
Pavlov. Cond. magazine entry latency0.00.00.1-0.3-0.10.10.1-0.2-0.2-0.2-0.3
Pavlov. Cond. change in total contacts0.40.63.8-1.9-0.3-0.2-0.3-0.6-0.4-0.4-0.5
Pavlov. Cond. index score0.40.51.3-1.1-0.5-0.3-0.4-0.7-0.6-0.6-0.7
Pavlov. Cond. latency score0.40.60.7-0.8-0.7-0.5-0.6-0.8-0.8-0.8-0.8
Pavlov. Cond. lever contacts0.81.11.5-0.2-1.1-1.0-1.1-1.2-1.2-1.2-1.2
Pavlov. Cond. magazine entry number0.10.10.50.70.0-0.2-0.10.10.10.10.1
Pavlov. Cond. intertrial magazine entries0.30.40.7-0.90.60.50.40.50.50.70.6
Pavlov. Cond. lever-magazine prob. diff.0.40.51.0-1.0-0.6-0.4-0.5-0.8-0.7-0.7-0.8
Pavlov. Cond. response bias0.50.71.0-1.0-0.8-0.6-0.7-0.9-0.9-0.9-1.0
Conditioned reinforcement - actives4.03.95.2-0.6-1.8-2.0-2.1-2.2-2.3-2.1-2.3
Conditioned reinforcement - inactives0.00.00.2-0.2-0.4-0.0-0.2-0.2-0.2-0.1-0.1
Conditioned locomotion2.12.63.4-0.6-1.2-1.6-1.8-1.8-1.8-1.8-1.8
Intermittent access intake day 1-15 change5.25.25.91.7-2.3-2.3-2.4-2.3-2.4-2.3-2.4
Intermittent access intake escalation4.14.04.61.5-2.1-2.0-2.1-2.0-2.1-2.1-2.1
Intermittent access intake escalation 25.65.56.91.3-2.3-2.3-2.5-2.5-2.6-2.4-2.6
Intermitt. access day 1 inactive lever presses1.11.21.71.20.81.00.91.31.21.01.3
Intermitt. access day 15 inactive lever presses0.50.53.61.9-0.20.30.30.30.40.20.5
Intermitt. access escalation Index0.10.10.40.6-0.40.10.00.30.20.30.5
Intermittent access day 1 total infusions1.61.83.0-0.5-1.7-1.1-1.2-1.6-1.4-1.4-1.5
Intermittent access day 15 total infusions7.28.110.30.5-3.2-2.7-2.9-3.2-3.0-3.0-3.2
Intermittent access terminal intake (last 3 days)7.17.711.10.7-3.3-2.4-2.6-3.1-2.9-2.9-3.3
Intermittent access total infusions4.34.86.90.4-2.5-1.9-2.0-2.6-2.3-2.4-2.6
Intermittent access day 1 locomotion0.40.41.3-0.3-1.1-0.3-0.3-0.8-0.5-0.6-0.7
Intermittent access day 15 total locomotion0.70.71.3-0.2-1.1-0.5-0.7-1.1-0.9-0.9-0.9
Intermittent access total locomotion0.80.91.70.3-1.3-0.6-0.7-1.3-0.9-1.0-1.1
Intermittent access standard deviation4.85.15.62.1-2.2-2.2-2.4-2.2-2.3-2.3-2.3
Cocaine induced anxiety0.20.20.30.50.20.50.50.50.40.40.4
Post-drug Anxiety2.02.23.0-0.31.71.41.41.61.61.51.7
Baseline Anxiety0.20.20.5-0.60.50.10.00.30.40.50.7
Lifetime Intake4.14.66.60.6-2.4-1.9-2.0-2.5-2.3-2.3-2.6
Incentive Sensitization - Responses1.81.82.6-1.2-1.1-1.2-1.3-1.6-1.4-1.3-1.5
Incentive Sensitization - Breakpoint1.91.92.6-1.1-1.2-1.3-1.4-1.6-1.5-1.4-1.5
Progressive ratio test 1 active lever presses2.72.84.01.8-2.0-1.4-1.5-1.7-1.5-1.7-1.7
Progressive ratio test 1 breakpoint2.72.83.91.5-2.0-1.3-1.4-1.7-1.6-1.8-1.9
Progressive ratio test 1 inactive lever presses0.10.10.70.8-0.5-0.0-0.1-0.1-0.0-0.0-0.1
Progressive ratio test 2 active lever presses3.03.24.30.1-1.8-1.7-1.8-2.1-1.9-1.9-2.0
Progressive ratio test 2 breakpoint2.73.04.2-0.1-1.7-1.7-1.8-2.0-1.9-1.9-2.0
Progressive ratio test 2 inactive lever presses1.71.92.90.4-1.7-1.2-1.3-1.6-1.5-1.5-1.5
Total sessions with >9 infusions1.01.02.31.0-1.5-0.6-0.7-1.0-0.8-1.0-1.1
Short access day 1 total inactive lever presses0.40.51.10.9-1.1-0.5-0.5-0.6-0.5-0.6-0.6
Short access day 10 total inactive lever presses0.30.41.71.30.30.10.10.70.40.50.5
Short access day 1 total infusions2.22.33.21.1-1.7-1.3-1.3-1.6-1.6-1.8-1.7
Short access day 10 total infusions2.42.64.01.0-2.0-1.5-1.6-1.8-1.6-1.7-1.6
Short access total infusions2.73.04.10.8-2.0-1.5-1.5-2.0-1.7-1.9-2.0
Short access day 1 locomotion0.20.30.60.8-0.80.0-0.0-0.4-0.3-0.6-0.5
Short access day 10 total locomotion1.11.21.70.40.71.31.21.11.21.21.1
Short access total locomotion0.40.41.10.3-1.0-0.3-0.3-0.8-0.5-0.7-0.8
Compulsive drug intake1.31.31.9-0.51.20.80.91.41.31.31.2
One hour access (0.3 mA shock)5.46.37.9-0.0-2.7-2.5-2.6-2.8-2.7-2.6-2.8
One hour access (shock baseline)7.99.212.20.7-3.5-2.8-3.0-3.4-3.2-3.2-3.4
Number of responses in last shaping day0.30.31.20.7-1.10.10.2-0.3-0.0-0.4-0.3
Context. condit. distance diff. score0.10.10.40.60.2-0.1-0.20.30.20.20.5
Locomotion velocity, session 12.52.73.4-0.51.81.71.71.81.81.71.7
Locomotion distance, session 11.11.41.6-1.31.21.21.21.11.11.11.1
Locomotion velocity, session 22.12.43.3-0.61.61.81.81.61.61.71.5
Locomotion distance, session 21.42.03.4-1.91.41.51.61.21.21.31.2
Locomotion velocity, session 30.00.00.10.30.0-0.0-0.00.0-0.0-0.00.1
Locomotion distance, session 30.20.20.3-0.6-0.5-0.4-0.4-0.6-0.5-0.5-0.4
Stereotopy head waving bouts, day 30.20.31.4-1.20.40.30.30.20.20.50.2
Stereotopy head waving duration, day 30.50.71.0-0.51.00.80.70.90.81.00.8
Locomotion velocity, session 74.34.75.6-1.9-2.1-2.1-2.1-2.4-2.4-2.2-2.3
Locomotion distance, session 74.05.16.4-0.3-2.3-2.4-2.4-2.4-2.5-2.4-2.4
Stereotopy head waving bouts, day 70.60.70.9-0.90.80.90.80.70.90.90.9
Stereotopy head waving duration, day 71.21.41.9-0.21.21.21.21.21.31.31.4
Locomotion velocity, session 83.84.66.1-0.22.32.12.12.32.42.32.5
Locomotion distance, session 81.21.83.0-0.71.51.21.11.41.41.51.7
Degree of sensitization distance0.30.30.40.0-0.6-0.7-0.7-0.6-0.7-0.6-0.7
Degree of sensitization stereotypy1.81.92.6-0.41.41.51.51.41.51.41.6
Condit. Reinf. active minus inactive responses5.46.07.6-2.82.42.62.72.12.32.42.1
Condit. Reinf. active-inactive response ratio7.07.58.9-3.02.72.93.02.42.72.72.5
Condit. Reinf. active responses4.25.18.2-2.92.22.42.41.92.02.21.9
Condit. Reinf. inactive responses0.10.10.2-0.40.30.30.20.20.10.30.2
Incentive salience index mean5.56.78.6-2.92.62.72.82.32.42.62.3
Condit. Reinf. lever presses2.43.23.4-1.71.81.81.81.71.81.81.8
Time in familiar zone, hab. session 10.80.72.11.5-0.6-1.0-0.9-0.6-0.6-0.7-0.6
Time in novel zone, hab. session 10.10.10.2-0.50.00.50.40.10.20.20.2
Total zone transitions, hab. session 11.01.41.8-1.11.31.21.21.21.21.21.2
Total locomotion distance, hab. session 10.40.52.3-1.50.60.70.60.40.50.50.5
Locomotion velocity, hab. session 10.71.02.8-1.70.91.11.00.70.80.90.8
Time in familiar zone, hab. session 22.02.14.92.2-1.1-1.6-1.4-1.0-1.3-1.3-1.2
Time in novel zone, hab. session 20.80.82.9-1.70.41.00.80.40.70.60.5
Total zone transitions, hab. session 20.40.50.80.30.90.70.60.80.70.70.8
Total locomotion distance, hab. session 20.20.20.4-0.60.50.60.50.30.40.40.4
Locomotion velocity, hab. session 20.10.10.2-0.50.40.50.40.30.30.30.3
Novel to familiar place preference ratio0.10.10.6-0.70.20.30.10.10.20.20.1
Novelty place preference0.00.00.2-0.5-0.00.2-0.0-0.00.00.1-0.1
Time in novel zone, NPP test0.00.00.1-0.20.00.20.00.10.10.10.0
Total zone transitions, NPP test0.81.21.8-0.11.31.11.01.21.21.11.3
Total locomotion distance, NPP test0.40.51.0-1.00.60.80.70.60.70.60.7
Locomotion velocity, NPP test0.20.31.2-1.10.30.50.40.20.30.30.4
Pavlov. Cond. lever latency0.60.80.91.0-0.8-0.9-0.9-0.8-0.9-0.9-0.8
Pavlov. Cond. magazine entry latency0.30.40.9-1.00.60.70.70.50.60.60.4
Pavlov. Cond. change in total contacts2.62.83.4-1.51.71.81.71.61.71.71.6
Pavlov. Cond. index score0.81.01.2-0.71.01.11.11.01.11.11.0
Pavlov. Cond. latency score0.71.01.1-0.61.01.11.01.01.11.00.9
Pavlov. Cond. lever contacts0.80.92.0-1.40.90.90.90.80.90.90.9
Pavlov. Cond. magazine entry number0.81.01.30.5-1.0-1.1-1.1-1.0-1.1-1.0-1.0
Pavlov. Cond. intertrial magazine entries0.50.60.9-0.1-0.7-0.9-0.9-0.8-0.9-0.8-0.7
Pavlov. Cond. lever-magazine prob. diff.0.81.01.1-0.71.01.11.01.01.11.01.0
Pavlov. Cond. response bias0.80.91.4-1.20.91.00.90.90.91.00.9
Bone: apparent density1.42.43.2-0.6-1.6-1.5-1.5-1.7-1.7-1.7-1.8
Bone surface2.44.25.3-1.8-2.0-2.0-2.0-2.3-2.1-1.9-2.3
Bone volume2.33.95.3-1.7-2.0-1.8-1.8-2.2-2.1-1.9-2.3
Bone: connectivity density1.72.73.3-0.2-1.7-1.7-1.8-1.7-1.7-1.7-1.8
Bone: cortical apparent density0.81.11.60.51.10.91.01.21.11.01.3
Bone: cortical area0.20.31.9-1.4-0.10.10.1-0.3-0.2-0.1-0.5
Bone: cortical porosity0.10.10.6-0.80.10.10.1-0.0-0.00.1-0.2
Bone: cortical porosity0.10.10.5-0.70.20.40.30.20.10.20.0
Bone: cortical thickness0.30.51.9-1.40.60.70.70.50.40.50.3
Bone: cortical thickness3.23.75.2-0.71.92.32.21.92.02.01.8
Bone: cortical tissue density0.81.11.60.51.10.91.01.21.11.01.3
Bone: elastic displacement0.30.32.3-1.50.10.30.20.00.10.20.3
Bone: elastic work0.30.32.6-1.6-0.10.10.1-0.3-0.2-0.1-0.2
Bone: endosteal estimation0.71.54.5-2.1-0.9-0.9-0.9-1.2-1.1-0.8-1.2
Bone: endosteal perimeter0.51.11.6-0.7-1.0-1.0-1.1-1.1-1.1-1.0-1.3
Bone: final force0.20.32.2-1.50.10.30.3-0.00.00.1-0.3
Bone: final moment0.20.31.9-1.4-0.2-0.2-0.1-0.4-0.4-0.2-0.6
Bone: marrow area0.61.34.6-2.2-0.8-0.8-0.8-1.1-0.9-0.7-1.1
Bone: maximum diameter0.20.40.9-0.3-0.6-0.4-0.4-0.7-0.6-0.6-0.9
Bone: maximum force0.20.43.0-1.7-0.10.20.2-0.3-0.1-0.0-0.4
Bone: maximum moment0.30.62.6-1.6-0.5-0.3-0.3-0.6-0.6-0.4-0.8
Bone: minimum diameter1.01.812.3-3.50.60.80.70.20.30.60.1
Bone: periosteal estimation0.61.16.9-2.6-0.4-0.2-0.3-0.7-0.6-0.4-0.9
Bone: periosteal perimeter0.40.71.1-0.9-0.7-0.6-0.7-0.9-0.9-0.7-1.1
Bone: post-yield work3.34.55.60.4-2.3-2.1-2.2-2.4-2.2-2.3-2.4
Bone: stiffness0.10.10.5-0.70.10.20.20.00.10.1-0.2
Bone: tissue strength2.22.22.51.0-1.6-1.6-1.5-1.5-1.4-1.5-1.5
Bone: trabecular number0.81.31.9-0.1-1.2-1.1-1.1-1.2-1.3-1.2-1.4
Bone: trabecular spacing1.31.72.00.51.41.31.31.41.41.31.4
Bone: trabecular thickness2.12.63.6-0.9-1.7-1.4-1.4-1.8-1.8-1.7-1.9
Bone: trabecular tissue density2.33.34.30.51.82.12.11.92.01.81.9
Breakpoint value in progressive ratio session1.61.82.4-0.61.41.41.51.41.41.51.3
Distance traveled before self-admin0.10.10.30.1-0.1-0.5-0.5-0.1-0.3-0.3-0.0
Distance traveled after self-admin0.10.10.60.8-0.6-0.3-0.2-0.1-0.10.00.1
Delta time in closed arm before/after self-admin0.20.20.30.2-0.3-0.5-0.5-0.4-0.4-0.5-0.2
Delta time in open arm before/after self-admin0.00.00.20.4-0.20.00.0-0.00.10.1-0.1
Diff in mean of infusions in LGA sessions2.02.22.7-1.21.41.61.61.41.51.61.5
Extinction: sum of active levers before priming1.01.01.6-0.11.01.31.10.91.21.01.0
Active lever presses in extinction session 60.40.40.70.4-0.5-0.6-0.5-0.7-0.7-0.6-0.9
Delta distance traveled before/after self-admin0.50.51.20.2-1.1-0.7-0.6-0.9-0.6-0.6-0.7
Delta ambulatory time before/after self-admin1.01.12.10.7-1.5-1.0-1.0-1.2-1.0-0.9-1.1
Time in closed arm before self-admin0.30.40.80.2-0.9-0.7-0.7-0.7-0.6-0.6-0.3
Time in closed arm after self-admin0.40.40.60.7-0.5-0.8-0.7-0.6-0.6-0.7-0.3
Time in open arm before self-admin0.20.21.2-1.1-0.1-0.0-0.0-0.2-0.2-0.2-0.3
Time in open arm after self-admin1.01.11.5-0.21.11.21.21.11.11.20.9
Sum of active levers in priming session hrs 5-60.30.30.9-0.9-0.2-0.2-0.2-0.6-0.6-0.5-0.6
Time to tail flick, vehicle, before self-admin1.21.21.9-0.1-1.0-0.9-1.1-1.1-1.2-1.4-1.3
Time to tail flick, vehicle, after self-admin2.32.53.50.1-1.4-1.8-1.9-1.7-1.7-1.7-1.6
Time to tail flick, test, before self-admin0.20.21.61.30.3-0.1-0.10.20.10.20.1
Time to tail flick, test, after self-admin0.70.81.31.0-1.2-0.7-0.7-0.8-0.8-0.8-0.9
Delta time to tail flick, vehicle, before/after SA0.90.91.3-0.2-1.1-1.1-1.1-1.0-0.9-0.9-0.9
Delta time to tail flick, test, before/after SA0.10.10.20.5-0.40.00.1-0.0-0.1-0.2-0.1
Ambulatory time before self-admin0.00.00.10.20.2-0.2-0.40.1-0.1-0.10.0
Ambulatory time after self-admin0.30.40.90.5-1.0-0.7-0.7-0.6-0.5-0.4-0.4
Total heroin consumption0.10.20.6-0.80.40.30.30.30.30.40.3
Area under the delay curve1.01.01.40.21.21.11.11.11.21.01.0
Delay disc. indifference point, 0s delay0.10.10.20.40.0-0.3-0.3-0.1-0.3-0.2-0.2
Delay disc. indifference point, 16s delay1.01.01.40.41.01.11.11.11.21.01.0
Delay disc. indifference point, 2s delay0.70.82.6-1.61.00.70.70.70.70.70.7
Delay disc. indifference point, 24s delay0.10.10.20.40.10.40.30.20.30.20.1
Delay disc. indifference point, 4s delay1.92.02.50.21.51.51.41.61.61.51.6
Delay disc. indifference point, 8s delay0.20.21.01.00.20.40.30.20.30.10.1
Delay discount exponential model param0.70.71.0-0.2-1.0-0.9-0.9-0.9-1.0-0.8-0.8
Delay discount hyperbolic model param1.01.11.5-0.1-1.2-1.1-1.1-1.1-1.2-1.0-1.0
Fecal boli incidents, locomotor time 10.30.30.5-0.40.70.60.50.60.60.70.5
Change in fecal boli incidents, locomotor task2.62.53.40.6-1.8-1.8-1.7-1.6-1.7-1.7-1.4
Time >=10cm from walls, locomotor time 11.11.11.6-0.5-1.2-1.0-1.0-1.3-1.2-1.2-0.8
Bouts of movement, locomotor time 10.70.85.72.4-0.1-0.1-0.30.0-0.1-0.3-0.3
Total resting periods, locomotor time 10.50.64.02.0-0.1-0.2-0.4-0.1-0.3-0.4-0.3
Rest time, locomotor task time 10.50.52.41.5-0.4-0.6-0.5-0.3-0.5-0.5-0.5
Distance moved, locomotor task time 10.00.00.1-0.3-0.2-0.1-0.0-0.1-0.1-0.1-0.1
Vertical activity count, locomotor time 10.30.32.3-1.5-0.0-0.10.0-0.1-0.1-0.0-0.2
Time >=10cm from walls, locomotor time 20.50.60.8-0.8-0.8-0.6-0.7-0.9-0.8-0.8-0.7
Bouts of movement, locomotor time 20.60.63.31.80.40.50.40.70.60.50.4
Total resting periods, locomotor time 20.70.73.92.00.40.50.50.70.60.40.4
Rest time, locomotor task time 20.30.31.11.00.50.60.50.50.40.30.5
Distance moved, locomotor task time 20.10.10.10.3-0.3-0.3-0.2-0.2-0.2-0.3-0.2
Vertical activity count, locomotor time 20.70.81.3-1.10.90.80.90.90.81.00.6
Weight adjusted by age0.10.20.30.10.40.60.50.40.50.40.0
Seeking ratio, delayed vs. immediate footshock8.810.011.61.5-3.4-3.4-3.3-3.3-3.3-3.3-3.3
Locomotion in novel chamber0.70.91.4-0.50.91.21.20.91.00.91.0
Locomotion in novel chamber post-restriction0.00.00.30.5-0.20.1-0.1-0.00.0-0.1-0.0
Progressive ratio0.91.02.81.7-1.2-0.8-0.8-0.8-0.8-0.9-0.6
Food seeking constrained by brief footshock3.13.84.6-1.82.02.11.91.91.72.02.1
Seeking ratio, punishment vs. effort3.34.05.9-2.42.31.91.81.91.82.01.8
Run reversals in cocaine runway, females0.90.92.00.40.70.91.01.00.90.91.4
Run reversals in cocaine runway, males3.23.13.6-1.21.81.81.81.71.91.81.8
Latency to leave start box in cocaine runway0.70.81.0-0.0-0.9-1.0-1.0-1.0-0.9-0.8-0.9
Latency to leave start box in cocaine runway, F3.03.34.50.3-1.9-2.1-2.1-1.9-1.9-1.8-1.8
Latency to leave start box in cocaine runway, M2.22.12.5-0.71.61.61.61.51.51.61.4
Cd content in liver1.31.41.81.31.21.01.01.31.21.11.2
Co content in liver0.30.41.41.20.40.20.20.60.60.40.7
Cu content in liver3.94.75.91.2-2.4-2.2-2.2-2.3-2.2-2.3-2.2
Fe content in liver0.70.84.3-2.1-0.5-0.4-0.4-0.8-0.6-0.5-0.5
K content in liver0.70.71.00.9-0.7-1.0-1.0-0.7-0.7-0.8-0.6
Mg content in liver0.50.50.60.1-0.7-0.8-0.8-0.7-0.7-0.7-0.6
Mn content in liver0.30.40.9-0.10.70.20.20.70.60.71.0
Na content in liver1.01.11.20.9-1.1-1.1-1.1-1.0-1.0-1.1-1.1
Rb content in liver0.00.00.20.50.00.30.20.10.1-0.00.1
Se content in liver0.10.10.40.6-0.3-0.5-0.5-0.3-0.2-0.3-0.1
Sr content in liver0.90.82.0-0.51.10.30.31.00.91.11.4
Zn content in liver1.41.62.11.1-1.3-1.4-1.4-1.2-1.2-1.2-1.2