Hub : Genes

Hadhb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr6:26181116:26187487 0.76 0 0.0e+00 0.33 0.34 0.33 0.34 8.5e-38 1.8e-38 4.2e-38 3.7e-39
2 Adipose intron excision ratio chr6:26181116:26187546 0.13 0.09 3.8e-13 0.1 0.1 0.1 0.1 2.6e-11 1.2e-11 1.5e-11 7.5e-11
3 Adipose intron excision ratio chr6:26181116:26187589 0.22 0.16 0.0e+00 0.18 0.18 0.18 0.19 1.5e-19 4.3e-20 3.0e-19 2.8e-20
4 Adipose mRNA stability ENSRNOG00000010800 0.1 0.08 2.8e-10 0.09 0.08 0.09 0.09 2.8e-10 1.2e-09 5.7e-10 7.9e-10
5 BLA intron excision ratio chr6:26181116:26187487 0.21 0.18 3.6e-08 0.14 0.12 0.12 0.15 5.4e-08 4.9e-07 4.0e-07 2.9e-08
6 BLA intron excision ratio chr6:26181116:26187589 0.07 0.07 2.3e-03 0.06 0.02 0.03 0.06 2.3e-04 3.0e-02 1.5e-02 6.7e-04
7 BLA mRNA stability ENSRNOG00000010800 0.05 0.06 9.7e-03 0.03 0.02 0.01 0.02 1.5e-02 2.3e-02 5.2e-02 3.7e-02
8 Brain gene expression ENSRNOG00000010800 0.03 0.03 2.4e-03 0.02 0.02 0.02 0.02 5.1e-03 2.6e-03 1.1e-02 8.2e-03
9 Brain intron excision ratio chr6:26181116:26187589 0.04 0.04 7.1e-04 0.03 0.03 0.03 0.03 1.6e-03 3.8e-04 1.3e-03 1.8e-03
10 Brain mRNA stability ENSRNOG00000010800 0.24 0.15 0.0e+00 0.21 0.23 0.21 0.23 2.5e-19 5.6e-21 1.3e-19 4.3e-21
11 LHb intron excision ratio chr6:26181116:26187487 0.18 0.17 2.1e-03 0.12 0.09 0.11 0.11 1.0e-03 3.4e-03 1.5e-03 1.6e-03
12 Liver gene expression ENSRNOG00000010800 0.35 0.17 0.0e+00 0.24 0.23 0.23 0.24 1.4e-26 1.1e-25 2.2e-25 2.6e-26
13 Liver intron excision ratio chr6:26181116:26187487 0.18 0.11 0.0e+00 0.19 0.19 0.19 0.2 4.6e-21 6.6e-21 3.4e-20 3.4e-21
14 Liver intron excision ratio chr6:26181116:26187589 0.17 0.11 0.0e+00 0.17 0.17 0.16 0.17 1.3e-18 1.8e-18 3.2e-17 7.8e-19
15 Liver mRNA stability ENSRNOG00000010800 0.05 0.05 1.3e-05 0.04 0.04 0.04 0.04 3.7e-05 1.0e-05 5.8e-05 8.7e-05
16 NAcc intron excision ratio chr6:26181116:26187487 0.13 0.11 7.0e-09 0.1 0.12 0.12 0.12 3.5e-08 2.8e-09 7.1e-09 5.9e-09
17 NAcc intron excision ratio chr6:26181116:26187589 0.06 0.07 8.7e-04 0.04 0.03 0.03 0.04 6.7e-04 3.8e-03 1.3e-03 1.0e-03
18 NAcc mRNA stability ENSRNOG00000010800 0.04 0.04 1.7e-03 0.03 0.04 0.04 0.04 1.4e-03 1.1e-03 7.1e-04 1.2e-03
19 OFC gene expression ENSRNOG00000010800 0.19 0.15 4.0e-04 0.06 0.13 0.1 0.09 1.4e-02 6.4e-04 2.7e-03 3.7e-03
20 OFC mRNA stability ENSRNOG00000010800 0.19 0.15 2.8e-04 0.11 0.1 0.11 0.12 1.8e-03 2.0e-03 1.2e-03 1.1e-03
21 PL intron excision ratio chr6:26181116:26187487 0.09 0.09 3.6e-06 0.07 0.07 0.06 0.07 3.0e-06 7.8e-06 1.2e-05 8.6e-06
22 PL mRNA stability ENSRNOG00000010800 0.07 0.08 1.2e-04 0.05 0.05 0.05 0.05 1.0e-04 1.6e-04 1.4e-04 1.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
BMI with tail2.68.59.63.1-2.9-3.1-3.02.7-2.7-2.8-2.9-2.9-3.02.9-2.92.9-2.9-2.92.9-2.9-3.1-2.9-3.02.7-2.8
BMI without tail0.51.01.51.0-1.0-1.0-1.10.7-0.7-0.7-1.0-1.0-1.01.2-1.11.0-1.0-1.01.1-1.2-0.9-1.1-1.00.7-1.0
Body weight2.19.011.83.0-2.9-3.0-3.12.9-2.9-3.3-3.0-3.0-3.12.9-2.92.8-2.8-2.92.9-2.9-3.4-2.9-3.03.1-2.9
Epididymis fat weight16.137.539.86.3-6.2-6.3-6.35.9-5.8-5.3-6.2-6.2-6.26.2-6.26.3-6.3-6.26.2-6.2-6.0-6.2-6.25.8-6.2
Glucose0.20.40.60.5-0.6-0.5-0.60.5-0.5-0.7-0.6-0.6-0.60.6-0.60.6-0.6-0.60.6-0.6-0.8-0.6-0.60.4-0.6
Heart weight4.76.77.32.6-2.6-2.6-2.42.6-2.6-2.7-2.6-2.6-2.52.6-2.62.6-2.6-2.62.6-2.6-2.7-2.6-2.62.4-2.6
Left kidney weight0.51.41.6-1.21.21.21.2-1.11.00.71.21.21.2-1.31.1-1.21.21.2-1.21.31.21.21.2-0.91.2
Right kidney weight0.10.31.00.5-0.5-0.5-0.40.6-0.6-1.0-0.5-0.5-0.40.4-0.60.5-0.5-0.50.4-0.4-0.6-0.4-0.50.7-0.6
Tail length0.10.40.5-0.70.60.70.6-0.70.70.60.70.60.6-0.50.7-0.70.70.7-0.60.50.70.60.7-0.60.6
Length with tail0.10.41.50.4-0.5-0.4-0.60.9-0.9-1.2-0.5-0.5-0.70.4-0.50.4-0.4-0.50.5-0.4-1.0-0.5-0.51.0-0.6
Length without tail0.20.41.90.4-0.4-0.4-0.50.9-1.0-1.4-0.4-0.4-0.60.1-0.40.3-0.3-0.40.3-0.1-1.1-0.3-0.41.0-0.5
Liver weight, left1.11.82.11.4-1.3-1.4-1.41.2-1.2-1.4-1.3-1.3-1.31.3-1.41.4-1.4-1.31.3-1.3-1.5-1.3-1.41.2-1.4
Liver weight, right5.99.713.73.0-3.0-3.0-3.23.2-3.2-3.6-3.0-3.1-3.22.9-3.03.0-3.1-3.13.0-2.9-3.7-3.0-3.13.2-3.1
Parametrial fat weight9.418.519.84.2-4.4-4.2-4.34.3-4.3-3.6-4.3-4.4-4.44.4-4.54.3-4.3-4.34.4-4.4-4.2-4.4-4.34.1-4.4
Retroperitoneal fat weight29.898.6102.810.0-10.1-10.0-10.09.7-9.7-8.7-10.0-10.0-10.010.1-10.110.0-10.0-10.010.1-10.1-9.8-10.1-10.19.7-10.1
Intraocular pressure4.76.610.02.5-2.5-2.5-2.52.7-2.7-3.2-2.5-2.5-2.52.3-2.42.5-2.5-2.52.5-2.3-3.1-2.5-2.52.8-2.5
Extensor digitorum longus weight2.08.112.7-2.72.82.72.9-2.62.63.12.82.82.9-2.82.8-2.82.82.8-2.82.83.62.82.8-2.62.7
Soleus weight2.67.512.0-2.72.72.72.9-2.62.63.12.72.72.8-2.72.7-2.72.72.7-2.72.73.52.72.7-2.52.6
Tibialis anterior weight0.72.54.7-1.61.61.61.6-1.21.22.01.61.61.5-1.61.6-1.61.61.6-1.61.62.21.61.6-1.21.5
Tibia length0.82.24.71.2-1.4-1.2-1.41.6-1.6-2.2-1.4-1.4-1.51.6-1.31.3-1.3-1.41.4-1.6-1.9-1.4-1.31.8-1.4
Number of licking bursts1.31.51.91.2-1.2-1.2-1.31.2-1.2-1.2-1.2-1.2-1.31.2-1.21.2-1.2-1.21.2-1.2-1.4-1.2-1.21.2-1.2
Food consumed during 24 hour testing period0.10.10.10.2-0.3-0.2-0.40.3-0.3-0.0-0.3-0.3-0.30.2-0.30.3-0.2-0.30.3-0.2-0.3-0.3-0.30.2-0.2
Times rat made contact with spout0.60.71.6-0.80.80.80.7-0.80.71.30.80.80.7-0.80.8-0.80.80.8-0.80.81.10.80.8-0.80.8
Mean time between licks in bursts1.82.53.81.5-1.6-1.5-1.61.6-1.6-1.8-1.6-1.6-1.61.5-1.61.6-1.6-1.61.6-1.5-1.9-1.6-1.61.5-1.5
Mean num. licks in bursts1.61.92.6-1.31.41.31.4-1.31.31.61.41.41.4-1.41.3-1.31.41.4-1.31.41.61.41.3-1.31.3
Std. dev. time between licks in bursts0.91.11.91.0-1.0-1.0-1.11.1-1.2-1.2-1.0-1.0-1.10.9-1.01.0-0.9-1.01.0-0.9-1.4-1.0-1.01.2-1.0
Water consumed over 24 hours0.00.00.0-0.10.10.10.0-0.00.00.20.10.10.0-0.20.1-0.10.10.1-0.10.20.20.10.1-0.10.1
Indifference point 0 sec0.60.91.60.7-0.9-0.7-1.11.2-1.3-0.8-0.9-1.0-1.20.8-0.80.9-0.8-0.90.9-0.8-1.0-0.9-0.81.3-0.9
Indifference point AUC0.00.00.00.10.0-0.1-0.10.0-0.00.0-0.00.0-0.1-0.2-0.20.0-0.10.00.00.20.1-0.0-0.10.00.0
Indifference point function ln k1.62.22.5-1.51.51.51.5-1.51.51.41.51.51.6-1.51.5-1.51.51.5-1.51.51.51.51.5-1.61.4
Indifference point function log k1.62.22.5-1.51.51.51.5-1.51.51.41.51.51.6-1.51.5-1.51.51.5-1.51.51.51.51.5-1.61.4
Delay discounting total patch changes 0 sec0.60.91.80.7-0.9-0.7-1.11.3-1.3-1.0-0.9-0.9-1.20.7-0.80.8-0.8-0.90.9-0.7-1.1-0.9-0.81.3-0.9
Delay discounting total patch changes 12 sec1.01.31.91.1-1.1-1.1-1.41.2-1.2-1.2-1.1-1.2-1.41.0-1.11.1-1.1-1.11.1-1.0-1.3-1.1-1.11.3-1.1
Delay discounting total patch changes 18 sec0.91.21.61.0-1.1-1.0-1.21.2-1.2-1.0-1.1-1.1-1.30.9-1.21.1-1.1-1.11.1-0.9-1.1-1.1-1.11.2-1.2
Delay discounting total patch changes 24 sec1.21.51.91.2-1.2-1.2-1.31.4-1.4-1.1-1.2-1.2-1.31.1-1.31.2-1.2-1.21.2-1.1-1.2-1.2-1.21.3-1.2
Delay discounting total patch changes 6 sec1.92.83.81.7-1.7-1.7-1.91.8-1.8-1.3-1.7-1.7-1.91.5-1.71.6-1.6-1.71.7-1.5-1.6-1.7-1.71.8-1.7
Delay discounting time to switch 0 sec0.20.40.70.6-0.6-0.6-0.60.4-0.4-0.5-0.6-0.6-0.60.8-0.50.6-0.6-0.60.6-0.8-0.7-0.7-0.60.4-0.6
Delay discounting water rate 0 sec1.01.62.4-1.41.41.41.3-0.80.81.11.31.31.2-1.51.3-1.31.31.3-1.41.51.31.41.4-0.81.3
Delay discounting water rate 12 sec0.10.10.10.3-0.3-0.3-0.20.4-0.4-0.2-0.3-0.3-0.20.4-0.30.3-0.3-0.30.3-0.4-0.2-0.3-0.30.3-0.3
Delay discounting water rate 18 sec1.11.41.7-1.31.21.31.2-1.11.11.11.21.21.2-1.11.2-1.31.31.2-1.21.11.31.21.2-1.11.1
Delay discounting water rate 24 sec0.10.10.30.4-0.3-0.4-0.30.4-0.4-0.6-0.3-0.3-0.30.2-0.40.4-0.4-0.30.3-0.2-0.4-0.3-0.40.4-0.4
Delay discounting water rate 6 sec0.10.10.2-0.40.40.40.3-0.20.20.20.40.40.3-0.40.4-0.40.40.4-0.40.40.30.40.4-0.20.4
Locomotor activity0.61.02.30.8-0.9-0.8-1.01.1-1.1-1.5-0.9-0.9-1.00.9-0.90.9-1.0-0.90.9-0.9-1.5-0.9-0.81.0-0.9
Locomotor testing distance0.30.60.80.6-0.8-0.6-0.70.8-0.8-0.7-0.7-0.8-0.70.9-0.80.8-0.8-0.80.7-0.9-0.9-0.8-0.70.7-0.8
Locomotor testing rearing0.40.60.8-0.90.80.90.7-0.60.60.60.80.80.7-0.80.8-0.80.80.8-0.80.80.60.80.9-0.50.8
Light reinforcement 10.50.92.0-1.10.91.10.9-0.50.41.40.90.90.7-0.91.1-1.11.11.0-1.00.91.10.91.0-0.41.0
Light reinforcement 21.21.52.4-1.21.31.21.1-1.01.01.61.21.21.0-1.41.3-1.31.31.3-1.21.41.41.21.2-1.01.2
Reaction time number correct0.20.20.8-0.50.40.50.6-0.40.40.90.40.40.5-0.40.4-0.30.30.4-0.40.40.90.40.4-0.50.3
Reaction time mean minus median0.10.10.60.0-0.1-0.0-0.0-0.50.50.8-0.1-0.00.10.20.00.0-0.0-0.00.1-0.20.5-0.1-0.1-0.5-0.0
Reaction time mean minus median AUC0.10.10.20.2-0.3-0.2-0.2-0.10.20.3-0.3-0.3-0.10.5-0.30.3-0.3-0.30.3-0.50.0-0.3-0.3-0.2-0.3
Reaction time num false alarms1.92.64.41.4-1.5-1.4-1.71.9-1.9-2.0-1.5-1.6-1.81.4-1.31.4-1.4-1.51.5-1.4-2.1-1.5-1.42.0-1.4
Reaction time num false alarms AUC1.92.64.41.4-1.5-1.4-1.71.9-2.0-1.9-1.6-1.6-1.81.4-1.31.4-1.4-1.51.5-1.4-2.1-1.5-1.42.0-1.4
Reaction time trials correct on left0.20.20.8-0.50.40.50.6-0.40.40.90.40.40.5-0.40.4-0.30.30.4-0.40.40.90.40.4-0.50.3
Reaction time trials on left0.20.20.8-0.50.40.50.6-0.40.40.90.40.40.5-0.30.4-0.30.30.4-0.40.30.90.40.4-0.50.3
Reaction time mean0.00.00.10.3-0.2-0.3-0.3-0.20.30.1-0.2-0.2-0.20.3-0.10.1-0.1-0.20.2-0.30.0-0.2-0.2-0.2-0.2
Reaction time mean AUC0.00.00.10.1-0.0-0.1-0.1-0.30.30.3-0.0-0.0-0.00.2-0.00.0-0.0-0.00.1-0.20.1-0.1-0.1-0.3-0.0
Median of all reaction times0.00.00.10.1-0.0-0.1-0.1-0.20.20.0-0.0-0.0-0.10.10.0-0.00.0-0.00.0-0.10.0-0.0-0.0-0.2-0.0
Reaction time omissions0.20.20.60.4-0.5-0.4-0.30.4-0.4-0.5-0.5-0.5-0.30.8-0.50.5-0.5-0.50.5-0.8-0.5-0.5-0.50.4-0.5
Reaction time false alarm rate2.33.35.81.6-1.7-1.6-1.92.0-2.0-2.2-1.7-1.8-2.01.6-1.61.6-1.6-1.71.7-1.6-2.4-1.7-1.62.2-1.6
Reaction time premature initiation rate0.10.20.30.3-0.4-0.3-0.50.5-0.5-0.4-0.4-0.4-0.50.5-0.40.4-0.4-0.40.4-0.5-0.6-0.4-0.40.5-0.5
Reaction time premature initiations0.00.00.10.0-0.2-0.0-0.10.2-0.20.1-0.2-0.1-0.20.2-0.20.2-0.2-0.20.2-0.2-0.1-0.2-0.10.2-0.2
Std. dev. reaction times0.20.20.50.5-0.5-0.5-0.5-0.00.10.3-0.5-0.5-0.30.7-0.50.5-0.5-0.50.5-0.7-0.1-0.5-0.5-0.1-0.5
Reaction time trials completed0.20.20.8-0.50.40.50.6-0.40.40.90.40.40.5-0.30.4-0.30.30.4-0.40.30.90.40.4-0.50.3
Reaction time trials AUC0.20.31.0-0.50.40.50.6-0.40.41.00.50.50.6-0.40.4-0.40.40.5-0.40.41.00.50.5-0.60.4
Social response proportion0.10.20.3-0.50.30.50.6-0.40.40.50.40.40.5-0.20.3-0.20.20.3-0.30.20.60.40.4-0.50.4
Social responses0.10.10.30.3-0.4-0.3-0.30.5-0.50.0-0.4-0.4-0.40.5-0.30.4-0.4-0.40.4-0.5-0.1-0.4-0.30.5-0.3
Social time0.10.20.4-0.50.30.50.6-0.30.30.50.30.30.4-0.20.4-0.20.20.3-0.30.20.60.30.4-0.40.4
Conditioned locomotion3.84.55.8-1.92.11.92.1-2.32.32.32.12.12.2-2.12.0-2.02.02.1-2.12.12.42.12.0-2.32.1
Cocaine response after cond. corrected0.20.20.3-0.40.40.40.5-0.40.40.40.40.40.5-0.50.4-0.40.40.4-0.40.50.50.40.4-0.40.4
Cocaine response after cond. not corrected0.70.81.0-0.90.90.91.0-0.90.91.00.90.91.0-0.90.9-0.90.90.9-0.90.91.00.90.9-0.90.9
Cocaine response before conditioning2.22.73.2-1.71.61.71.6-1.71.71.71.61.61.6-1.51.6-1.61.61.6-1.61.51.81.61.7-1.61.6
Saline control response1.41.82.2-1.31.41.31.4-1.11.11.01.41.41.3-1.51.5-1.41.41.4-1.41.51.41.41.4-0.91.5
Condit. Reinf. active minus inactive responses1.31.63.5-1.21.21.21.2-1.01.01.91.21.31.2-1.21.2-1.21.21.2-1.21.21.61.21.2-1.11.2
Condit. Reinf. active-inactive response ratio0.60.71.0-0.80.80.80.9-0.70.71.00.80.80.8-0.90.8-0.80.80.8-0.80.90.90.80.8-0.70.8
Condit. Reinf. active responses0.81.13.5-0.91.00.90.9-0.80.81.91.01.00.9-0.91.0-1.01.01.0-0.90.91.51.00.9-0.90.9
Condit. Reinf. inactive responses0.20.21.3-0.40.40.40.3-0.40.41.20.40.40.3-0.40.5-0.40.40.4-0.40.40.90.40.4-0.40.4
Condit. Reinf. lever presses1.11.53.5-1.11.21.11.1-1.21.21.91.21.21.2-1.11.1-1.21.21.2-1.11.11.51.21.1-1.21.2
Condit. Reinf. lever reinforcers received0.70.93.3-0.80.90.80.8-0.70.71.80.90.90.8-0.90.9-0.90.90.9-0.90.91.40.90.8-0.80.9
Pavlov. Cond. lever latency0.91.22.81.0-1.0-1.0-1.01.2-1.2-1.7-1.0-1.0-1.11.0-1.01.0-1.0-1.01.0-1.0-1.4-1.0-1.01.2-1.0
Pavlov. Cond. magazine entry latency0.00.00.10.1-0.1-0.1-0.1-0.00.10.2-0.1-0.1-0.10.1-0.10.2-0.2-0.10.1-0.1-0.0-0.1-0.2-0.1-0.1
Pavlov. Cond. change in total contacts0.10.10.7-0.00.10.00.1-0.30.30.80.10.20.2-0.20.1-0.10.00.1-0.10.20.50.10.0-0.40.1
Pavlov. Cond. index score0.30.41.3-0.50.60.50.5-0.70.81.10.60.60.6-0.60.6-0.60.50.6-0.60.60.80.60.5-0.80.6
Pavlov. Cond. latency score0.30.41.2-0.50.60.50.5-0.80.81.10.60.60.6-0.70.6-0.60.50.6-0.60.70.80.60.5-0.80.6
Pavlov. Cond. lever contacts0.30.41.3-0.50.50.50.5-0.70.71.10.50.50.6-0.50.5-0.50.50.5-0.50.50.90.50.5-0.70.5
Pavlov. Cond. magazine entry number0.10.10.2-0.40.30.40.4-0.20.1-0.10.30.30.3-0.30.4-0.40.40.3-0.40.30.20.40.4-0.10.3
Pavlov. Cond. intertrial magazine entries2.63.43.91.7-1.8-1.7-1.81.9-1.9-1.9-1.8-1.8-1.81.9-1.81.8-1.7-1.81.8-1.9-2.0-1.8-1.82.0-1.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.7-0.20.30.20.2-0.40.40.80.30.30.3-0.30.3-0.20.20.3-0.20.30.50.30.2-0.50.3
Pavlov. Cond. response bias0.40.61.8-0.60.70.60.7-0.90.91.30.70.70.7-0.70.6-0.60.60.7-0.60.71.00.60.6-0.90.7
Conditioned reinforcement - actives4.24.26.1-2.02.02.02.2-2.22.21.82.02.02.3-1.81.9-2.02.02.0-2.01.82.32.02.0-2.51.9
Conditioned reinforcement - inactives5.56.27.0-2.52.52.52.5-2.62.61.72.52.52.5-2.62.6-2.62.62.5-2.52.62.22.52.5-2.62.6
Conditioned locomotion3.84.55.5-2.12.12.12.1-2.22.22.02.12.12.2-2.12.2-2.02.02.1-2.12.12.32.12.1-2.32.1
Intermittent access intake day 1-15 change1.81.82.2-1.31.41.31.5-1.41.40.81.41.41.5-1.31.3-1.41.41.4-1.41.31.21.41.4-1.31.3
Intermittent access intake escalation1.01.01.3-1.01.01.01.2-1.11.10.41.01.01.1-1.00.9-1.01.01.0-1.01.00.81.01.0-1.00.9
Intermittent access intake escalation 20.10.10.20.3-0.2-0.3-0.20.1-0.1-0.5-0.2-0.2-0.10.2-0.20.2-0.2-0.20.2-0.2-0.3-0.2-0.20.3-0.2
Intermitt. access day 1 inactive lever presses0.10.10.2-0.00.20.00.2-0.20.20.40.20.20.2-0.50.1-0.20.20.2-0.20.50.50.20.1-0.20.1
Intermitt. access day 15 inactive lever presses1.82.03.5-1.31.31.31.3-1.41.41.91.31.31.3-1.31.5-1.41.41.3-1.31.31.71.31.3-1.51.5
Intermitt. access escalation Index2.92.63.91.5-1.6-1.5-1.41.6-1.5-1.7-1.6-1.6-1.51.6-1.71.7-1.7-1.61.6-1.6-2.0-1.6-1.51.7-1.7
Intermittent access day 1 total infusions4.14.66.9-2.02.12.02.0-2.22.22.52.12.12.1-2.02.1-2.22.22.1-2.12.02.62.12.0-2.32.1
Intermittent access day 15 total infusions4.45.05.5-2.12.22.12.3-2.32.31.92.22.22.3-2.22.2-2.32.32.2-2.22.22.32.22.2-2.42.2
Intermittent access terminal intake (last 3 days)3.84.15.1-1.82.01.82.0-2.22.21.82.02.02.0-2.02.0-2.12.12.0-2.02.02.22.02.0-2.32.0
Intermittent access total infusions5.45.97.1-2.42.42.42.4-2.62.62.12.42.42.4-2.42.4-2.52.52.4-2.42.42.52.42.4-2.72.4
Intermittent access day 1 locomotion2.42.52.8-1.61.61.61.5-1.51.51.31.61.61.5-1.71.6-1.61.61.6-1.61.71.51.61.6-1.61.6
Intermittent access day 15 total locomotion0.50.51.3-0.60.70.60.8-1.01.00.60.70.70.8-0.60.7-0.60.60.7-0.70.60.80.70.7-1.10.7
Intermittent access total locomotion1.01.11.6-1.01.01.01.1-1.21.20.61.01.01.1-1.01.1-1.01.01.0-1.01.01.01.01.1-1.31.1
Intermittent access standard deviation0.70.71.0-0.90.90.90.8-0.80.80.70.90.90.8-0.80.9-0.80.80.9-0.90.81.00.90.9-0.70.9
Cocaine induced anxiety0.00.00.1-0.20.20.20.1-0.10.1-0.20.20.20.2-0.20.2-0.20.20.2-0.20.2-0.10.20.2-0.10.2
Post-drug Anxiety1.51.62.41.2-1.2-1.2-1.21.3-1.3-1.5-1.2-1.3-1.31.2-1.21.2-1.2-1.21.2-1.2-1.4-1.2-1.21.4-1.2
Baseline Anxiety1.31.41.51.2-1.2-1.2-1.21.1-1.1-0.7-1.2-1.2-1.21.2-1.21.2-1.2-1.21.2-1.2-0.9-1.2-1.21.1-1.2
Lifetime Intake6.16.88.3-2.62.62.62.6-2.82.82.32.62.62.6-2.52.6-2.72.62.6-2.62.52.72.62.6-2.92.6
Incentive Sensitization - Responses1.51.52.2-1.21.31.21.1-1.11.10.21.31.21.1-1.41.5-1.51.51.3-1.31.40.61.31.3-1.01.5
Incentive Sensitization - Breakpoint1.01.01.5-0.91.00.90.8-0.90.90.11.01.00.9-1.11.2-1.21.21.0-1.11.10.41.01.0-0.71.2
Progressive ratio test 1 active lever presses3.33.44.4-1.81.81.81.9-2.12.11.61.81.81.9-1.71.8-1.91.91.8-1.81.71.91.81.8-2.11.8
Progressive ratio test 1 breakpoint2.52.63.4-1.61.61.61.7-1.81.81.51.61.61.7-1.51.5-1.61.61.6-1.51.51.71.61.5-1.81.5
Progressive ratio test 1 inactive lever presses5.96.37.7-2.42.42.42.6-2.82.82.72.42.42.7-2.42.4-2.42.42.4-2.42.42.82.42.4-2.82.4
Progressive ratio test 2 active lever presses2.42.63.2-1.51.61.51.6-1.71.71.01.61.61.7-1.61.7-1.81.81.6-1.61.61.41.61.5-1.71.7
Progressive ratio test 2 breakpoint2.52.83.5-1.61.71.61.6-1.81.81.11.71.71.7-1.71.8-1.91.91.7-1.71.71.51.71.6-1.71.8
Progressive ratio test 2 inactive lever presses3.33.84.3-1.81.91.81.9-2.02.01.71.91.92.0-1.92.1-2.12.11.9-1.91.92.01.91.9-2.02.1
Total sessions with >9 infusions7.17.78.8-3.02.83.02.9-2.92.92.22.82.82.9-2.72.7-2.82.82.8-2.82.72.72.82.8-2.92.7
Short access day 1 total inactive lever presses3.03.45.0-1.81.71.82.1-2.22.21.81.71.72.1-1.51.7-1.61.61.7-1.71.52.21.71.7-2.21.7
Short access day 10 total inactive lever presses0.10.10.20.5-0.2-0.5-0.40.4-0.40.3-0.2-0.2-0.20.2-0.20.2-0.2-0.20.3-0.2-0.0-0.3-0.30.4-0.2
Short access day 1 total infusions5.35.67.0-2.52.32.52.4-2.62.62.22.32.32.4-2.22.2-2.32.32.3-2.32.22.62.32.3-2.62.2
Short access day 10 total infusions6.87.59.3-2.62.72.62.7-3.03.12.52.72.72.8-2.72.7-2.72.72.7-2.72.72.92.72.7-3.02.7
Short access total infusions5.66.17.7-2.62.42.62.5-2.72.82.22.42.42.5-2.32.3-2.42.42.4-2.42.32.62.42.4-2.82.3
Short access day 1 locomotion6.26.69.3-2.72.52.72.6-2.72.73.02.52.52.6-2.32.3-2.42.42.5-2.42.33.12.42.5-2.92.3
Short access day 10 total locomotion1.51.62.1-1.41.31.41.2-1.11.11.31.31.31.2-1.31.3-1.21.21.3-1.21.31.21.31.3-1.21.3
Short access total locomotion2.62.63.4-1.81.61.81.6-1.71.71.61.61.61.6-1.61.5-1.51.51.6-1.61.61.71.61.6-1.81.5
Compulsive drug intake3.93.94.81.8-2.0-1.8-1.81.9-1.8-2.0-1.9-1.9-1.82.0-2.12.2-2.2-2.01.9-2.0-2.1-1.9-1.92.0-2.1
One hour access (0.3 mA shock)2.22.63.5-1.51.61.51.6-1.81.91.11.61.61.7-1.51.5-1.61.61.6-1.61.51.71.61.5-1.71.5
One hour access (shock baseline)6.37.38.3-2.52.72.52.6-2.92.82.22.72.72.7-2.82.8-2.82.82.7-2.72.82.82.72.6-2.92.8
Number of responses in last shaping day2.82.93.3-1.71.71.71.4-1.81.81.61.71.71.6-1.71.7-1.81.81.7-1.71.71.81.71.7-1.71.7
Context. condit. distance diff. score0.20.20.3-0.50.50.50.5-0.40.40.50.50.50.5-0.40.5-0.50.50.5-0.50.40.50.50.5-0.40.5
Locomotion velocity, session 10.80.91.80.8-0.9-0.8-0.81.0-1.0-1.4-0.9-0.9-0.90.7-0.90.9-0.9-0.90.9-0.7-1.3-0.9-0.91.1-0.9
Locomotion distance, session 10.20.30.4-0.70.60.70.6-0.20.20.20.60.60.5-0.60.6-0.60.60.6-0.60.60.40.60.6-0.10.6
Locomotion velocity, session 20.00.00.10.1-0.2-0.1-0.10.3-0.4-0.2-0.2-0.2-0.10.2-0.10.1-0.1-0.20.1-0.2-0.2-0.1-0.10.4-0.1
Locomotion distance, session 20.10.20.60.3-0.3-0.3-0.20.7-0.7-0.4-0.3-0.3-0.40.3-0.40.4-0.4-0.30.3-0.3-0.3-0.3-0.30.8-0.4
Locomotion velocity, session 30.10.10.6-0.20.20.20.2-0.10.10.80.20.20.2-0.20.1-0.10.10.2-0.20.20.70.20.2-0.10.2
Locomotion distance, session 30.00.00.20.2-0.2-0.2-0.20.4-0.40.1-0.2-0.2-0.20.1-0.20.2-0.2-0.20.2-0.10.0-0.2-0.20.4-0.2
Stereotopy head waving bouts, day 32.22.74.5-1.61.61.61.5-1.61.62.11.61.61.6-1.51.6-1.61.61.6-1.61.51.91.61.6-1.61.6
Stereotopy head waving duration, day 30.60.81.3-0.90.80.90.8-0.90.91.10.80.80.9-0.70.9-0.90.90.9-0.80.71.00.80.9-0.90.9
Locomotion velocity, session 70.00.00.30.2-0.1-0.2-0.20.0-0.00.5-0.1-0.1-0.10.1-0.10.1-0.1-0.10.2-0.10.3-0.2-0.20.0-0.1
Locomotion distance, session 70.91.21.41.2-1.1-1.2-1.11.1-1.1-1.0-1.1-1.1-1.11.0-1.11.1-1.1-1.11.1-1.0-1.2-1.1-1.11.1-1.0
Stereotopy head waving bouts, day 70.00.00.4-0.10.00.1-0.00.0-0.00.60.00.0-0.0-0.10.0-0.00.00.0-0.00.10.20.00.00.0-0.0
Stereotopy head waving duration, day 70.50.61.7-0.70.70.70.7-0.70.71.30.70.70.7-0.70.7-0.70.70.7-0.70.71.10.70.7-0.70.7
Locomotion velocity, session 80.50.60.8-0.80.80.80.9-0.80.80.80.80.80.9-0.70.8-0.80.80.8-0.80.70.80.80.8-0.80.7
Locomotion distance, session 80.30.40.6-0.70.60.70.7-0.40.40.80.60.60.6-0.60.6-0.60.60.6-0.60.60.80.60.7-0.40.6
Degree of sensitization distance0.90.91.51.0-0.9-1.0-1.00.8-0.7-1.2-0.9-0.9-0.90.9-0.90.9-0.9-0.90.9-0.9-1.2-0.9-1.00.7-0.9
Degree of sensitization stereotypy0.30.30.40.5-0.5-0.5-0.50.6-0.6-0.0-0.5-0.5-0.60.5-0.60.6-0.6-0.50.6-0.5-0.3-0.5-0.50.6-0.6
Condit. Reinf. active minus inactive responses2.02.32.91.5-1.5-1.5-1.41.4-1.4-1.5-1.5-1.5-1.41.7-1.51.5-1.5-1.51.5-1.7-1.6-1.5-1.51.4-1.6
Condit. Reinf. active-inactive response ratio1.71.82.51.3-1.4-1.3-1.31.1-1.1-1.3-1.4-1.4-1.21.6-1.31.3-1.3-1.41.4-1.6-1.4-1.4-1.31.1-1.4
Condit. Reinf. active responses0.10.20.30.4-0.4-0.4-0.30.3-0.3-0.4-0.4-0.4-0.30.6-0.40.4-0.4-0.40.4-0.6-0.4-0.4-0.40.3-0.5
Condit. Reinf. inactive responses1.01.11.3-1.11.11.11.1-0.90.81.11.11.11.1-1.11.1-1.11.11.1-1.11.11.11.11.1-0.81.0
Incentive salience index mean0.20.30.40.5-0.5-0.5-0.40.5-0.5-0.6-0.5-0.5-0.40.6-0.50.5-0.5-0.50.5-0.6-0.6-0.5-0.50.5-0.5
Condit. Reinf. lever presses0.50.70.8-0.80.90.80.9-0.70.70.70.90.80.8-0.90.8-0.80.80.8-0.90.90.80.90.8-0.70.9
Time in familiar zone, hab. session 10.90.82.20.9-0.8-0.9-0.80.9-0.9-1.5-0.9-0.9-0.80.9-0.80.8-0.8-0.90.8-0.9-1.3-0.8-0.80.9-0.8
Time in novel zone, hab. session 10.20.20.30.4-0.5-0.4-0.50.5-0.50.0-0.5-0.5-0.50.5-0.50.5-0.5-0.50.5-0.5-0.3-0.5-0.50.4-0.5
Total zone transitions, hab. session 10.10.10.3-0.40.40.40.6-0.30.30.30.40.40.5-0.30.4-0.40.40.4-0.40.30.40.40.4-0.30.3
Total locomotion distance, hab. session 10.71.01.9-0.91.00.91.1-1.01.01.31.01.01.0-0.91.0-1.01.01.0-1.00.91.41.01.0-1.00.9
Locomotion velocity, hab. session 11.42.03.3-1.31.41.31.4-1.41.51.81.41.41.5-1.21.3-1.31.31.4-1.31.21.81.41.4-1.51.3
Time in familiar zone, hab. session 20.30.30.40.5-0.5-0.5-0.60.5-0.5-0.5-0.5-0.6-0.50.5-0.50.5-0.5-0.50.5-0.5-0.6-0.5-0.50.5-0.5
Time in novel zone, hab. session 20.00.00.10.1-0.1-0.1-0.10.1-0.1-0.3-0.1-0.1-0.10.1-0.10.1-0.1-0.10.1-0.1-0.2-0.1-0.10.1-0.1
Total zone transitions, hab. session 20.30.30.80.5-0.5-0.5-0.40.8-0.8-0.5-0.5-0.6-0.50.6-0.60.6-0.6-0.50.5-0.6-0.5-0.5-0.50.9-0.6
Total locomotion distance, hab. session 20.20.30.40.5-0.6-0.5-0.50.6-0.6-0.1-0.6-0.6-0.50.6-0.60.6-0.6-0.60.6-0.6-0.3-0.6-0.60.6-0.5
Locomotion velocity, hab. session 20.10.10.20.4-0.4-0.4-0.40.4-0.40.0-0.4-0.4-0.40.4-0.40.4-0.4-0.40.4-0.4-0.1-0.4-0.40.4-0.4
Novel to familiar place preference ratio0.40.50.80.7-0.7-0.7-0.80.9-0.9-0.2-0.7-0.7-0.80.6-0.70.7-0.7-0.70.7-0.6-0.6-0.7-0.70.9-0.6
Novelty place preference0.80.81.20.9-0.9-0.9-1.01.1-1.1-0.5-0.9-0.9-1.00.8-0.90.9-0.9-0.90.9-0.8-0.8-0.9-0.91.1-0.9
Time in novel zone, NPP test0.70.81.20.9-0.8-0.9-0.91.1-1.1-0.5-0.8-0.8-1.00.7-0.80.8-0.8-0.80.8-0.7-0.8-0.8-0.91.1-0.8
Total zone transitions, NPP test0.70.91.4-1.11.01.11.2-0.70.60.71.01.01.0-1.01.0-1.01.01.0-1.01.00.91.01.1-0.61.0
Total locomotion distance, NPP test1.11.51.7-1.31.31.31.3-1.01.01.21.31.31.2-1.31.2-1.21.21.3-1.31.31.31.31.3-1.01.3
Locomotion velocity, NPP test1.52.12.5-1.51.51.51.5-1.31.21.51.51.51.5-1.51.5-1.51.51.5-1.51.51.61.51.5-1.21.5
Pavlov. Cond. lever latency0.40.50.70.7-0.7-0.7-0.80.6-0.6-0.5-0.7-0.7-0.70.8-0.70.7-0.7-0.70.7-0.8-0.7-0.7-0.70.6-0.7
Pavlov. Cond. magazine entry latency0.00.10.10.2-0.2-0.2-0.20.3-0.3-0.3-0.2-0.3-0.30.2-0.20.2-0.2-0.30.2-0.2-0.3-0.2-0.20.3-0.2
Pavlov. Cond. change in total contacts0.00.00.1-0.20.20.20.2-0.0-0.00.00.20.20.2-0.20.2-0.20.20.2-0.20.20.10.20.20.00.2
Pavlov. Cond. index score0.00.00.1-0.20.20.20.2-0.00.00.10.20.20.2-0.30.2-0.20.20.2-0.20.30.10.20.2-0.00.2
Pavlov. Cond. latency score0.00.00.0-0.10.10.10.10.1-0.1-0.10.10.00.0-0.10.0-0.00.00.0-0.10.1-0.10.10.10.20.1
Pavlov. Cond. lever contacts0.30.40.5-0.70.70.70.7-0.50.50.50.70.60.6-0.70.6-0.60.60.7-0.70.70.60.70.7-0.50.7
Pavlov. Cond. magazine entry number0.00.00.0-0.00.00.0-0.0-0.10.1-0.00.00.00.00.00.0-0.00.00.0-0.0-0.00.00.00.0-0.10.0
Pavlov. Cond. intertrial magazine entries2.22.63.0-1.61.61.61.6-1.71.71.51.61.61.7-1.51.6-1.61.61.6-1.61.51.71.61.6-1.71.5
Pavlov. Cond. lever-magazine prob. diff.0.30.40.5-0.70.70.70.7-0.50.50.60.70.60.6-0.70.6-0.60.60.6-0.70.70.60.70.6-0.50.7
Pavlov. Cond. response bias0.91.11.2-1.01.01.01.1-1.01.01.11.01.01.0-1.11.0-1.01.01.0-1.01.11.11.01.0-1.01.0
Bone: apparent density2.94.75.8-2.12.22.12.2-2.12.12.12.22.22.2-2.32.2-2.12.22.2-2.22.32.42.22.1-2.22.2
Bone surface0.50.91.1-1.01.01.00.9-0.80.80.81.00.90.9-1.01.0-1.01.01.0-1.01.00.91.01.0-0.81.0
Bone volume1.52.52.9-1.61.61.61.5-1.41.41.51.61.61.5-1.71.6-1.61.61.6-1.61.71.71.61.6-1.51.7
Bone: connectivity density1.72.73.1-1.71.71.71.8-1.61.51.31.71.71.7-1.71.7-1.71.71.7-1.71.71.71.71.7-1.61.7
Bone: cortical apparent density0.00.00.1-0.00.10.00.2-0.40.40.00.10.10.3-0.00.0-0.00.00.1-0.10.00.10.10.1-0.30.0
Bone: cortical area0.10.10.50.2-0.2-0.2-0.30.6-0.7-0.5-0.2-0.3-0.40.2-0.20.2-0.2-0.20.2-0.2-0.2-0.2-0.20.7-0.2
Bone: cortical porosity3.63.85.4-1.92.01.91.9-1.71.72.32.02.01.8-2.12.0-2.02.02.0-2.02.12.32.01.9-1.72.0
Bone: cortical porosity2.83.04.4-1.61.71.61.7-1.51.52.01.71.71.6-1.81.7-1.71.71.7-1.71.82.11.71.7-1.61.8
Bone: cortical thickness0.30.50.90.7-0.7-0.7-0.70.9-0.9-0.6-0.7-0.7-0.70.7-0.60.6-0.6-0.70.7-0.7-0.4-0.7-0.70.9-0.6
Bone: cortical thickness0.40.50.8-0.70.70.70.6-0.60.60.70.70.70.6-0.70.7-0.70.70.7-0.70.70.90.70.7-0.60.7
Bone: cortical tissue density0.00.00.10.1-0.0-0.10.1-0.30.3-0.10.00.00.20.1-0.00.0-0.0-0.00.0-0.10.00.0-0.0-0.2-0.1
Bone: elastic displacement1.71.92.7-1.41.31.41.3-1.51.51.41.31.31.4-1.21.3-1.31.31.3-1.31.21.61.31.3-1.61.3
Bone: elastic work0.40.61.0-0.80.70.80.6-0.80.80.90.70.70.7-0.60.8-0.80.80.7-0.70.61.00.70.7-0.80.7
Bone: endosteal estimation0.10.10.2-0.50.40.50.3-0.20.2-0.20.40.30.2-0.40.4-0.40.40.4-0.40.40.00.40.4-0.20.4
Bone: endosteal perimeter0.00.00.1-0.10.00.1-0.20.2-0.2-0.30.0-0.0-0.2-0.10.1-0.10.10.0-0.00.1-0.10.00.00.20.0
Bone: final force0.00.00.20.2-0.1-0.2-0.20.4-0.4-0.4-0.1-0.1-0.30.1-0.10.1-0.1-0.10.1-0.1-0.2-0.1-0.10.4-0.1
Bone: final moment0.00.00.20.1-0.1-0.1-0.10.3-0.3-0.4-0.1-0.1-0.20.1-0.10.1-0.1-0.10.1-0.1-0.1-0.1-0.10.3-0.1
Bone: marrow area0.10.10.2-0.50.40.50.3-0.30.3-0.10.40.40.3-0.50.4-0.40.40.4-0.40.50.10.40.4-0.20.4
Bone: maximum diameter0.00.00.1-0.10.00.1-0.10.3-0.3-0.20.0-0.0-0.1-0.00.1-0.10.10.0-0.00.00.00.00.00.30.0
Bone: maximum force0.00.10.20.2-0.1-0.2-0.30.4-0.5-0.5-0.1-0.2-0.30.1-0.10.1-0.1-0.10.1-0.1-0.2-0.1-0.10.4-0.1
Bone: maximum moment0.00.00.10.1-0.1-0.1-0.20.3-0.3-0.4-0.1-0.1-0.20.10.00.0-0.0-0.10.1-0.1-0.1-0.1-0.10.3-0.0
Bone: minimum diameter0.61.02.00.8-0.9-0.8-1.01.4-1.4-1.4-0.9-1.0-1.10.9-0.80.8-0.8-0.90.9-0.9-1.1-0.9-0.91.4-0.9
Bone: periosteal estimation0.10.10.2-0.50.40.50.3-0.00.0-0.10.40.30.2-0.40.5-0.50.50.4-0.40.40.20.40.4-0.00.4
Bone: periosteal perimeter0.00.00.20.0-0.1-0.0-0.30.4-0.4-0.4-0.1-0.1-0.30.1-0.00.0-0.0-0.10.1-0.1-0.1-0.1-0.10.4-0.0
Bone: post-yield work1.92.53.1-1.81.61.81.6-1.51.51.11.61.61.6-1.51.6-1.61.61.6-1.61.51.51.61.7-1.51.6
Bone: stiffness0.20.20.60.5-0.4-0.5-0.50.7-0.8-0.7-0.4-0.4-0.50.4-0.40.4-0.4-0.40.4-0.4-0.5-0.4-0.40.8-0.4
Bone: tissue strength0.50.50.70.8-0.8-0.8-0.60.6-0.5-0.4-0.7-0.7-0.60.8-0.80.8-0.8-0.80.8-0.8-0.5-0.8-0.80.5-0.8
Bone: trabecular number3.14.85.3-2.22.22.22.1-2.12.11.72.22.22.2-2.32.3-2.32.32.2-2.22.32.22.22.2-2.22.3
Bone: trabecular spacing0.91.11.71.0-1.0-1.0-1.01.2-1.2-1.2-1.0-1.0-1.01.1-1.01.0-1.0-1.01.0-1.1-1.3-1.0-1.01.2-1.0
Bone: trabecular thickness0.40.50.8-0.60.70.60.6-0.70.70.90.70.70.6-0.80.7-0.70.70.7-0.70.80.90.70.6-0.80.7
Bone: trabecular tissue density0.20.20.5-0.40.40.40.5-0.70.70.70.40.40.6-0.30.3-0.30.30.4-0.40.30.60.40.4-0.70.4
Breakpoint value in progressive ratio session0.91.01.3-0.81.10.80.9-1.01.00.31.11.10.9-1.11.1-1.11.11.1-1.11.10.61.11.0-1.01.1
Distance traveled before self-admin0.20.21.0-0.40.30.40.6-0.60.61.00.30.40.6-0.30.1-0.20.20.3-0.30.30.90.30.3-0.70.1
Distance traveled after self-admin0.20.20.40.6-0.5-0.6-0.40.6-0.6-0.4-0.5-0.5-0.40.4-0.60.5-0.5-0.50.5-0.4-0.5-0.5-0.50.5-0.6
Delta time in closed arm before/after self-admin0.40.41.50.4-0.5-0.4-0.80.9-1.0-1.2-0.5-0.5-0.80.4-0.40.3-0.3-0.50.5-0.4-1.1-0.5-0.50.9-0.4
Delta time in open arm before/after self-admin0.10.10.2-0.10.20.10.4-0.40.40.20.20.20.4-0.20.1-0.10.10.2-0.20.20.40.20.1-0.30.1
Diff in mean of infusions in LGA sessions0.00.00.1-0.20.20.20.2-0.10.1-0.20.20.20.2-0.30.2-0.20.20.2-0.20.3-0.10.20.2-0.20.2
Extinction: sum of active levers before priming0.50.50.7-0.70.80.70.6-0.50.4-0.40.70.70.6-0.80.8-0.80.80.7-0.80.80.10.80.8-0.40.8
Active lever presses in extinction session 61.81.72.1-1.11.31.11.3-1.41.40.71.31.31.3-1.51.4-1.41.41.3-1.41.51.11.41.3-1.31.4
Delta distance traveled before/after self-admin1.92.02.91.5-1.3-1.5-1.51.5-1.5-1.5-1.4-1.4-1.61.3-1.31.2-1.2-1.31.3-1.3-1.7-1.3-1.41.5-1.3
Delta ambulatory time before/after self-admin0.40.50.80.7-0.6-0.7-0.90.8-0.9-0.8-0.6-0.6-0.90.5-0.50.5-0.5-0.60.6-0.5-0.9-0.6-0.70.9-0.5
Time in closed arm before self-admin0.10.20.30.5-0.4-0.5-0.30.2-0.1-0.5-0.4-0.4-0.30.1-0.60.5-0.5-0.40.4-0.1-0.5-0.4-0.50.3-0.6
Time in closed arm after self-admin0.70.81.71.0-0.8-1.0-0.90.7-0.6-1.3-0.9-0.8-0.80.7-0.90.9-0.9-0.90.8-0.7-1.2-0.8-0.90.7-0.9
Time in open arm before self-admin0.00.00.20.0-0.1-0.0-0.40.4-0.5-0.1-0.1-0.1-0.40.20.1-0.10.1-0.10.1-0.2-0.2-0.1-0.10.40.1
Time in open arm after self-admin0.20.30.5-0.60.50.60.7-0.40.40.60.50.50.6-0.30.5-0.50.50.5-0.50.30.70.50.5-0.50.5
Sum of active levers in priming session hrs 5-60.20.20.60.6-0.3-0.6-0.60.7-0.7-0.7-0.3-0.3-0.70.2-0.20.2-0.2-0.30.3-0.2-0.7-0.3-0.40.7-0.2
Time to tail flick, vehicle, before self-admin0.60.61.31.0-0.7-1.0-0.90.7-0.7-1.0-0.7-0.7-0.80.6-0.60.5-0.6-0.70.7-0.6-1.1-0.7-0.80.6-0.6
Time to tail flick, vehicle, after self-admin5.86.27.82.6-2.6-2.6-2.31.9-1.9-1.9-2.6-2.5-2.22.7-2.82.8-2.8-2.62.7-2.7-2.2-2.6-2.71.8-2.8
Time to tail flick, test, before self-admin1.11.11.7-1.01.11.00.9-1.21.20.91.11.11.0-1.11.1-1.11.11.1-1.11.10.81.11.0-1.31.1
Time to tail flick, test, after self-admin1.01.01.3-0.91.00.91.0-0.90.90.81.01.01.0-1.11.1-1.11.11.0-1.01.10.91.01.0-0.91.1
Delta time to tail flick, vehicle, before/after SA2.02.02.81.3-1.5-1.3-1.21.1-1.1-0.4-1.5-1.4-1.21.6-1.71.7-1.7-1.51.5-1.6-0.8-1.5-1.51.1-1.7
Delta time to tail flick, test, before/after SA1.71.62.0-1.31.21.31.3-1.11.01.21.21.21.3-1.31.3-1.31.31.2-1.31.31.41.31.3-1.11.3
Ambulatory time before self-admin0.20.20.8-0.30.30.30.6-0.50.50.90.30.30.6-0.30.1-0.10.10.3-0.30.30.70.30.3-0.60.1
Ambulatory time after self-admin0.10.10.20.4-0.3-0.4-0.20.4-0.4-0.2-0.3-0.3-0.30.2-0.40.3-0.3-0.30.3-0.2-0.3-0.3-0.30.3-0.4
Total heroin consumption1.31.51.9-1.11.31.11.1-1.31.30.61.31.31.2-1.31.3-1.41.41.3-1.31.30.91.31.3-1.31.3
Area under the delay curve0.00.00.20.4-0.2-0.4-0.30.1-0.10.0-0.2-0.2-0.20.1-0.10.2-0.1-0.20.2-0.1-0.0-0.2-0.30.1-0.1
Delay disc. indifference point, 0s delay1.31.42.11.3-1.1-1.3-1.31.2-1.2-1.4-1.1-1.1-1.21.0-1.01.1-1.1-1.11.1-1.0-1.4-1.1-1.11.2-1.0
Delay disc. indifference point, 16s delay0.10.10.20.5-0.3-0.5-0.40.3-0.30.3-0.3-0.3-0.30.2-0.20.2-0.2-0.30.3-0.20.0-0.3-0.30.3-0.2
Delay disc. indifference point, 2s delay0.10.10.30.5-0.3-0.5-0.50.5-0.5-0.1-0.3-0.3-0.50.2-0.30.4-0.3-0.30.3-0.2-0.2-0.3-0.40.5-0.3
Delay disc. indifference point, 24s delay2.62.52.8-1.51.61.51.7-1.51.51.51.61.61.6-1.61.7-1.61.61.6-1.61.61.71.61.5-1.51.7
Delay disc. indifference point, 4s delay0.20.20.40.6-0.5-0.6-0.60.4-0.4-0.5-0.5-0.5-0.50.5-0.40.5-0.5-0.50.5-0.5-0.5-0.5-0.50.4-0.4
Delay disc. indifference point, 8s delay0.00.00.1-0.00.10.00.1-0.20.30.40.10.10.2-0.10.1-0.10.10.1-0.10.10.40.10.0-0.30.1
Delay discount exponential model param0.00.00.1-0.2-0.00.20.10.1-0.1-0.3-0.0-0.0-0.10.1-0.10.0-0.1-0.0-0.0-0.1-0.3-0.00.10.1-0.1
Delay discount hyperbolic model param0.00.00.1-0.20.10.20.20.0-0.0-0.20.10.00.0-0.0-0.0-0.10.00.1-0.10.0-0.10.10.10.0-0.0
Fecal boli incidents, locomotor time 12.93.13.6-1.81.81.81.8-1.61.61.31.81.81.7-1.91.8-1.81.81.8-1.81.91.71.81.8-1.61.8
Change in fecal boli incidents, locomotor task3.53.44.41.9-1.8-1.9-1.81.9-1.9-2.1-1.8-1.8-1.81.8-1.81.8-1.8-1.81.8-1.8-2.1-1.8-1.81.8-1.8
Time >=10cm from walls, locomotor time 10.40.40.5-0.70.70.70.6-0.60.60.20.70.70.6-0.70.7-0.70.70.7-0.70.70.50.70.7-0.70.7
Bouts of movement, locomotor time 10.10.11.50.10.0-0.1-0.00.1-0.11.20.00.0-0.0-0.00.1-0.10.10.1-0.00.00.80.0-0.00.00.1
Total resting periods, locomotor time 10.10.12.00.10.1-0.10.00.1-0.11.40.10.1-0.0-0.10.1-0.20.20.1-0.10.10.90.10.1-0.00.1
Rest time, locomotor task time 10.10.11.0-0.00.10.00.1-0.10.11.00.10.10.1-0.10.1-0.10.10.1-0.10.10.60.10.1-0.10.1
Distance moved, locomotor task time 10.30.31.70.4-0.4-0.4-0.50.4-0.4-1.3-0.4-0.4-0.50.4-0.40.4-0.4-0.40.4-0.4-1.1-0.4-0.40.4-0.4
Vertical activity count, locomotor time 10.30.31.10.5-0.5-0.5-0.50.4-0.4-1.0-0.5-0.5-0.50.5-0.50.4-0.4-0.50.5-0.5-0.9-0.5-0.50.4-0.5
Time >=10cm from walls, locomotor time 21.61.72.0-1.31.31.31.2-1.31.31.21.31.41.3-1.41.3-1.31.31.3-1.31.41.41.31.3-1.31.3
Bouts of movement, locomotor time 20.60.61.10.8-0.8-0.8-0.81.0-1.0-0.2-0.8-0.8-0.90.8-0.80.8-0.8-0.80.8-0.8-0.6-0.8-0.80.8-0.8
Total resting periods, locomotor time 20.70.71.10.9-0.9-0.9-0.81.0-1.0-0.1-0.9-0.9-0.90.8-0.90.8-0.8-0.80.9-0.8-0.5-0.9-0.90.9-0.9
Rest time, locomotor task time 20.10.11.2-0.0-0.10.0-0.0-0.10.11.1-0.1-0.00.00.1-0.10.1-0.1-0.00.1-0.10.6-0.1-0.00.1-0.1
Distance moved, locomotor task time 20.10.10.6-0.10.20.10.1-0.10.1-0.80.20.20.1-0.20.3-0.20.30.2-0.20.2-0.50.20.2-0.30.3
Vertical activity count, locomotor time 20.30.30.5-0.50.60.50.5-0.50.5-0.00.60.60.5-0.70.7-0.70.70.6-0.60.70.20.60.6-0.60.7
Weight adjusted by age0.30.30.60.6-0.6-0.6-0.70.8-0.80.0-0.6-0.6-0.70.4-0.50.6-0.5-0.60.6-0.4-0.4-0.6-0.60.7-0.5
Seeking ratio, delayed vs. immediate footshock0.00.00.10.1-0.1-0.1-0.10.3-0.3-0.0-0.1-0.1-0.2-0.1-0.0-0.00.0-0.10.10.10.0-0.1-0.10.3-0.0
Locomotion in novel chamber0.40.50.60.8-0.7-0.8-0.70.7-0.7-0.8-0.7-0.7-0.70.6-0.70.7-0.7-0.70.7-0.6-0.8-0.7-0.80.5-0.7
Locomotion in novel chamber post-restriction3.33.96.71.8-1.8-1.8-2.12.2-2.2-2.6-1.9-1.9-2.11.5-1.91.9-1.9-1.91.8-1.5-2.5-1.8-1.92.2-1.9
Progressive ratio0.20.20.6-0.40.50.40.4-0.20.20.40.50.50.3-0.80.5-0.50.50.5-0.50.80.30.50.4-0.30.5
Food seeking constrained by brief footshock14.617.821.6-4.44.44.44.0-3.73.62.94.44.34.0-4.74.5-4.54.54.4-4.44.73.84.44.4-3.64.5
Seeking ratio, punishment vs. effort1.41.71.9-1.41.31.41.3-1.31.30.81.41.31.4-1.21.3-1.41.41.3-1.41.21.31.41.4-1.21.3
Run reversals in cocaine runway, females0.40.40.6-0.50.60.50.6-0.70.80.70.60.60.7-0.60.6-0.50.50.6-0.60.60.70.60.5-0.80.6
Run reversals in cocaine runway, males1.21.21.8-1.01.11.01.0-1.11.11.21.11.11.2-1.11.0-1.01.01.1-1.11.11.31.11.0-1.11.0
Latency to leave start box in cocaine runway0.50.61.3-0.60.60.60.7-1.01.01.20.70.70.7-0.60.7-0.70.70.7-0.60.61.10.60.7-1.00.6
Latency to leave start box in cocaine runway, F0.10.10.3-0.40.30.40.3-0.50.50.50.30.30.3-0.10.4-0.40.40.3-0.30.10.40.30.4-0.60.3
Latency to leave start box in cocaine runway, M2.02.03.3-1.21.31.21.3-1.61.61.71.31.41.4-1.41.2-1.21.21.3-1.31.41.81.31.2-1.61.2
Cd content in liver0.40.40.80.5-0.6-0.5-0.60.9-0.9-0.8-0.6-0.6-0.70.7-0.50.5-0.5-0.60.6-0.7-0.8-0.6-0.50.7-0.5
Co content in liver5.26.17.6-2.52.42.52.5-2.62.62.72.42.42.5-2.22.4-2.42.42.4-2.42.22.72.42.5-2.52.4
Cu content in liver0.10.10.1-0.40.30.40.3-0.30.3-0.30.30.30.3-0.30.3-0.30.30.3-0.30.3-0.10.30.3-0.20.3
Fe content in liver0.10.10.3-0.50.40.50.3-0.00.0-0.40.40.30.3-0.40.4-0.40.40.4-0.40.4-0.10.40.40.10.3
K content in liver1.91.93.61.2-1.3-1.2-1.41.5-1.5-1.6-1.3-1.4-1.51.3-1.31.3-1.3-1.31.3-1.3-1.9-1.3-1.31.6-1.3
Mg content in liver1.92.03.91.1-1.3-1.1-1.51.7-1.7-2.0-1.3-1.3-1.61.2-1.21.2-1.2-1.31.3-1.2-1.9-1.3-1.21.7-1.2
Mn content in liver0.30.30.50.5-0.5-0.5-0.70.7-0.7-0.4-0.5-0.5-0.70.3-0.50.5-0.5-0.50.5-0.3-0.4-0.5-0.60.7-0.5
Na content in liver1.81.92.5-1.51.51.51.3-1.31.21.01.41.41.3-1.61.4-1.41.41.4-1.51.61.11.51.4-1.11.5
Rb content in liver0.50.71.70.7-0.7-0.7-0.81.0-1.0-1.3-0.7-0.8-0.80.7-0.60.6-0.6-0.70.7-0.7-1.3-0.7-0.70.9-0.6
Se content in liver1.11.33.00.9-1.0-0.9-1.11.4-1.4-1.7-1.0-1.0-1.20.9-1.01.0-1.0-1.01.0-0.9-1.6-1.0-1.01.3-1.0
Sr content in liver0.00.00.10.2-0.2-0.2-0.2-0.00.00.1-0.2-0.2-0.20.2-0.20.2-0.2-0.20.2-0.2-0.2-0.2-0.2-0.0-0.2
Zn content in liver1.61.83.31.1-1.2-1.1-1.41.6-1.6-1.7-1.3-1.3-1.51.2-1.21.2-1.2-1.31.2-1.2-1.8-1.2-1.21.5-1.1