Lysmd2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000010642 0.06 0.04 2.1e-04 0.01 0 -0 0 5.9e-02 1.8e-01 7.3e-01 1.6e-01
2 Brain alternative polyA ENSRNOT00000083410 0.04 0.03 4.3e-03 0.03 0.02 0.01 0.01 1.8e-03 2.9e-03 2.1e-02 1.2e-02
3 Brain alternative polyA ENSRNOT00000110573 0.04 0.03 4.5e-03 0.01 0.02 0.01 0.01 2.0e-02 3.4e-03 3.1e-02 1.5e-02
4 Brain mRNA stability ENSRNOG00000010642 0.03 0.02 2.0e-03 0.02 0.03 0.03 0.02 4.6e-03 2.2e-03 2.2e-03 4.3e-03
5 LHb gene expression ENSRNOG00000010642 0.2 0.1 8.3e-04 0.07 0.12 0.15 0.12 1.2e-02 1.1e-03 2.0e-04 1.1e-03
6 Liver gene expression ENSRNOG00000010642 0.09 0.05 2.3e-06 0.01 0.03 0.04 0.02 1.2e-02 4.2e-04 6.6e-05 1.2e-03
7 PL isoform ratio ENSRNOT00000014301 0.05 0.03 2.8e-03 0.04 0.04 0.05 -0 8.5e-04 6.9e-04 5.5e-05 7.2e-01
8 PL intron excision ratio chr8:76392603:76393842 0.04 0.03 1.6e-03 0.03 0.03 0.03 0.02 5.0e-03 5.3e-03 5.3e-03 8.8e-03
9 PL mRNA stability ENSRNOG00000010642 0.04 0.03 1.5e-03 0.03 0.03 0.03 -0 3.0e-03 1.8e-03 2.6e-03 8.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail1.54.811.9-1.1-2.43.10.3-3.5-2.90.9-2.30.3
BMI without tail0.30.72.5-1.5-0.40.5-0.2-1.6-0.50.6-0.40.1
Body weight1.25.214.2-2.0-2.02.90.8-3.8-2.61.8-2.10.9
Epididymis fat weight4.29.814.6-3.03.3-3.13.12.13.83.23.23.2
Glucose0.10.20.80.30.5-0.50.20.90.4-0.30.50.0
Heart weight0.30.51.4-1.20.50.10.9-0.3-0.20.90.50.8
Left kidney weight0.20.71.7-0.8-0.41.00.7-1.3-0.91.0-0.30.7
Right kidney weight0.10.31.4-0.6-0.30.7-0.1-1.2-0.40.7-0.40.1
Tail length0.20.51.8-1.30.5-0.8-0.5-0.60.80.60.4-0.0
Length with tail0.20.72.6-1.2-0.50.70.2-1.6-0.51.0-0.60.3
Length without tail1.43.17.30.3-2.12.70.6-2.2-2.50.6-2.10.3
Liver weight, left0.20.41.0-0.1-0.71.00.3-0.7-1.00.2-0.60.2
Liver weight, right0.40.72.4-1.60.10.20.7-0.9-0.21.30.20.8
Parametrial fat weight0.10.20.8-0.40.5-0.80.00.40.90.10.50.2
Retroperitoneal fat weight1.65.49.7-3.12.2-1.82.30.52.23.12.12.6
Intraocular pressure0.10.20.7-0.80.20.20.6-0.3-0.60.20.10.4
Extensor digitorum longus weight0.41.65.4-0.5-1.31.0-1.4-2.3-0.9-0.2-1.4-1.1
Soleus weight4.613.326.41.0-4.33.6-3.6-5.1-3.7-1.9-4.3-3.4
Tibialis anterior weight3.210.914.61.8-3.73.3-3.3-3.8-3.7-2.5-3.8-3.3
Tibia length1.33.69.30.2-2.13.00.7-2.2-2.80.9-2.10.6
Number of licking bursts2.02.43.81.1-1.91.5-1.6-1.6-1.3-1.1-1.9-1.6
Food consumed during 24 hour testing period5.56.615.71.0-3.13.6-0.6-2.9-4.0-0.8-3.1-1.0
Times rat made contact with spout2.02.35.70.4-1.82.1-0.4-1.7-2.4-0.3-1.8-0.6
Mean time between licks in bursts0.20.20.4-0.10.3-0.20.50.50.60.60.40.6
Mean num. licks in bursts0.70.82.4-0.90.70.01.50.3-0.51.10.71.4
Std. dev. time between licks in bursts0.50.61.60.7-0.70.1-1.3-0.50.6-0.7-0.7-1.1
Water consumed over 24 hours2.42.85.90.5-2.12.2-0.6-2.0-2.4-0.5-2.1-0.8
Indifference point 0 sec0.30.41.00.7-0.50.5-0.4-0.3-0.8-1.0-0.7-0.7
Indifference point AUC1.31.52.8-1.70.9-1.10.70.31.61.71.11.2
Indifference point function ln k1.42.04.01.8-1.11.2-1.0-0.5-1.8-2.0-1.2-1.5
Indifference point function log k1.42.04.01.8-1.11.2-1.0-0.5-1.8-2.0-1.2-1.5
Delay discounting total patch changes 0 sec0.10.20.70.4-0.30.5-0.0-0.3-0.8-0.6-0.6-0.3
Delay discounting total patch changes 12 sec0.81.02.1-1.01.1-1.00.70.71.51.20.91.0
Delay discounting total patch changes 18 sec0.10.10.4-0.20.20.10.40.4-0.00.50.10.6
Delay discounting total patch changes 24 sec0.50.71.4-1.20.9-1.20.20.31.10.41.00.4
Delay discounting total patch changes 6 sec0.40.61.8-0.50.9-1.3-0.30.61.3-0.10.8-0.1
Delay discounting time to switch 0 sec0.40.51.40.70.6-0.9-0.11.21.1-0.40.7-0.1
Delay discounting water rate 0 sec1.11.75.6-0.4-1.31.60.0-1.8-2.4-0.1-1.4-0.2
Delay discounting water rate 12 sec1.21.93.90.6-1.51.2-1.0-1.4-2.0-1.5-1.4-1.3
Delay discounting water rate 18 sec0.40.62.0-1.40.6-0.31.2-0.0-0.40.60.50.9
Delay discounting water rate 24 sec0.00.10.2-0.00.2-0.40.10.2-0.1-0.50.1-0.2
Delay discounting water rate 6 sec1.21.73.00.5-1.41.2-1.1-1.5-1.7-1.3-1.3-1.3
Locomotor activity0.20.30.60.1-0.70.70.5-0.6-0.50.1-0.60.3
Locomotor testing distance0.10.20.50.2-0.50.60.5-0.2-0.7-0.4-0.50.1
Locomotor testing rearing0.10.10.20.1-0.30.10.4-0.1-0.4-0.5-0.20.0
Light reinforcement 10.91.65.9-1.1-1.11.50.2-2.4-1.11.0-1.20.4
Light reinforcement 20.30.31.11.1-0.60.90.20.1-0.6-0.2-0.50.2
Reaction time number correct0.50.82.61.0-0.3-0.3-1.1-0.00.4-1.6-0.3-1.3
Reaction time mean minus median1.21.62.6-0.81.4-0.81.61.31.01.21.41.5
Reaction time mean minus median AUC0.70.91.8-0.21.0-0.61.21.30.90.51.01.0
Reaction time num false alarms0.70.91.90.01.3-1.40.31.31.3-0.11.10.3
Reaction time num false alarms AUC0.81.12.40.11.3-1.60.21.41.5-0.31.10.2
Reaction time trials correct on left0.50.82.61.0-0.3-0.3-1.1-0.00.4-1.6-0.3-1.3
Reaction time trials on left0.60.82.61.1-0.2-0.4-1.10.10.5-1.6-0.2-1.3
Reaction time mean0.60.91.7-0.11.0-0.51.31.20.70.70.91.1
Reaction time mean AUC0.40.61.20.10.9-0.41.01.10.60.50.80.8
Median of all reaction times0.50.71.30.01.0-0.51.11.10.70.60.91.0
Reaction time omissions1.62.25.9-0.01.7-2.20.41.82.40.21.60.4
Reaction time false alarm rate0.81.21.8-0.51.3-1.30.91.31.10.71.21.0
Reaction time premature initiation rate0.20.30.8-0.90.00.20.9-0.4-0.30.50.10.6
Reaction time premature initiations0.00.10.2-0.3-0.10.10.3-0.4-0.1-0.3-0.0-0.1
Std. dev. reaction times1.31.83.1-0.51.5-1.11.51.81.40.91.61.3
Reaction time trials completed0.60.82.61.1-0.2-0.4-1.10.10.5-1.6-0.2-1.3
Reaction time trials AUC0.70.93.11.2-0.4-0.3-1.2-0.00.3-1.8-0.4-1.4
Social response proportion0.50.52.70.30.4-0.01.60.70.10.20.31.1
Social responses0.10.10.5-0.1-0.10.20.7-0.20.30.3-0.30.5
Social time0.10.10.50.7-0.20.10.40.10.1-0.6-0.1-0.1
Conditioned locomotion1.11.43.5-1.40.8-0.51.40.10.81.90.81.6
Cocaine response after cond. corrected1.92.15.40.6-1.72.0-0.4-1.5-2.3-0.7-1.8-0.7
Cocaine response after cond. not corrected2.93.28.50.5-2.12.60.0-2.0-2.9-0.2-2.2-0.3
Cocaine response before conditioning1.11.32.9-0.4-1.31.50.3-1.7-1.30.8-1.30.3
Saline control response0.70.93.51.9-0.40.4-0.40.7-0.7-1.5-0.5-0.8
Condit. Reinf. active minus inactive responses1.41.73.61.1-1.31.1-0.8-0.9-1.9-1.7-1.3-1.3
Condit. Reinf. active-inactive response ratio1.11.23.01.5-0.90.7-0.5-0.0-1.4-1.7-0.9-1.0
Condit. Reinf. active responses1.11.53.4-0.0-1.41.5-0.5-1.7-1.9-0.4-1.5-0.7
Condit. Reinf. inactive responses0.70.92.8-1.2-0.70.90.0-1.7-0.51.2-0.70.3
Condit. Reinf. lever presses2.33.26.71.6-2.02.2-0.9-1.3-2.6-1.6-2.0-1.3
Condit. Reinf. lever reinforcers received1.01.43.6-0.1-1.31.5-0.2-1.6-1.9-0.3-1.4-0.4
Pavlov. Cond. lever latency2.33.14.4-1.22.1-1.81.51.72.01.52.01.7
Pavlov. Cond. magazine entry latency0.70.81.81.30.3-0.8-0.41.31.1-0.90.4-0.5
Pavlov. Cond. change in total contacts0.40.60.80.4-0.90.8-0.6-0.8-0.9-0.6-0.9-0.7
Pavlov. Cond. index score1.11.42.11.4-1.30.8-1.3-0.7-0.8-1.4-1.2-1.4
Pavlov. Cond. latency score1.62.13.01.7-1.61.1-1.5-0.7-1.1-1.7-1.5-1.6
Pavlov. Cond. lever contacts2.43.35.01.3-2.22.0-1.5-1.8-2.0-1.5-2.2-1.6
Pavlov. Cond. magazine entry number0.60.71.9-1.40.30.31.0-0.6-0.41.30.31.1
Pavlov. Cond. intertrial magazine entries0.20.30.7-0.7-0.30.40.2-0.8-0.20.8-0.30.4
Pavlov. Cond. lever-magazine prob. diff.0.91.11.61.3-1.20.7-1.2-0.5-0.6-1.2-1.1-1.3
Pavlov. Cond. response bias0.71.01.61.0-1.20.6-1.3-0.8-0.6-1.1-1.1-1.3
Conditioned reinforcement - actives0.10.10.30.5-0.20.0-0.00.30.5-0.3-0.1-0.1
Conditioned reinforcement - inactives0.20.30.5-0.60.4-0.30.70.20.60.60.50.6
Conditioned locomotion0.81.03.0-0.90.40.11.40.2-0.01.70.51.5
Intermittent access intake day 1-15 change0.20.20.6-0.30.00.30.8-0.20.50.50.10.5
Intermittent access intake escalation0.30.31.10.1-0.71.00.3-1.0-0.30.1-0.60.0
Intermittent access intake escalation 20.80.81.50.7-1.11.2-0.5-1.2-0.5-0.6-1.0-0.7
Intermitt. access day 1 inactive lever presses0.10.10.3-0.30.4-0.30.10.10.00.60.50.2
Intermitt. access day 15 inactive lever presses2.12.35.8-2.01.3-0.91.50.31.22.41.31.7
Intermitt. access escalation Index3.12.77.10.1-1.62.60.8-2.0-2.70.2-1.70.5
Intermittent access day 1 total infusions0.91.02.0-0.31.1-0.81.01.40.91.01.11.1
Intermittent access day 15 total infusions0.30.30.8-0.20.30.20.90.30.50.90.40.8
Intermittent access terminal intake (last 3 days)0.20.20.6-0.1-0.20.70.5-0.3-0.20.8-0.10.6
Intermittent access total infusions0.10.20.50.40.20.10.50.70.10.40.30.5
Intermittent access day 1 locomotion2.02.13.3-1.11.5-1.11.31.31.21.81.61.7
Intermittent access day 15 total locomotion0.50.51.4-0.50.7-0.50.60.60.41.20.80.8
Intermittent access total locomotion0.00.00.20.10.10.0-0.00.2-0.30.50.20.2
Intermittent access standard deviation0.20.20.8-0.3-0.20.3-0.1-0.50.40.9-0.10.2
Cocaine induced anxiety0.30.30.90.3-0.1-0.6-0.80.40.9-0.5-0.1-0.6
Post-drug Anxiety1.41.65.7-0.21.0-2.0-0.51.52.4-0.11.0-0.2
Baseline Anxiety1.81.92.8-1.21.7-1.51.21.31.41.21.71.1
Lifetime Intake0.60.61.4-0.00.8-0.50.81.20.80.80.90.9
Incentive Sensitization - Responses0.30.30.7-0.40.3-0.30.60.20.80.80.40.6
Incentive Sensitization - Breakpoint0.60.61.2-0.70.6-0.60.80.31.11.00.60.8
Progressive ratio test 1 active lever presses0.20.20.8-0.2-0.10.50.6-0.2-0.50.9-0.00.7
Progressive ratio test 1 breakpoint0.30.30.8-0.1-0.20.70.4-0.3-0.60.9-0.20.6
Progressive ratio test 1 inactive lever presses0.30.30.8-0.20.5-0.20.70.40.40.90.50.7
Progressive ratio test 2 active lever presses0.20.20.6-0.20.30.00.60.10.40.80.30.6
Progressive ratio test 2 breakpoint0.10.10.30.00.10.10.40.10.30.50.20.4
Progressive ratio test 2 inactive lever presses0.60.71.5-0.10.6-0.70.91.21.00.90.70.9
Total sessions with >9 infusions0.10.10.40.6-0.10.5-0.4-0.1-0.30.2-0.2-0.2
Short access day 1 total inactive lever presses0.40.41.0-0.70.40.31.0-0.1-0.41.00.40.9
Short access day 10 total inactive lever presses0.10.10.20.20.0-0.30.10.30.3-0.40.1-0.1
Short access day 1 total infusions0.20.30.7-0.00.4-0.30.30.60.70.80.50.5
Short access day 10 total infusions0.30.31.21.10.2-0.2-0.11.10.2-0.10.3-0.1
Short access total infusions1.51.63.4-0.21.4-1.01.11.91.41.11.41.2
Short access day 1 locomotion0.20.20.60.0-0.20.6-0.3-0.7-0.40.6-0.2-0.1
Short access day 10 total locomotion0.20.20.80.3-0.30.3-0.9-0.3-0.5-0.1-0.3-0.6
Short access total locomotion0.20.21.1-0.10.30.00.10.30.01.10.40.4
Compulsive drug intake0.70.72.31.2-0.60.90.10.3-1.5-1.0-0.6-0.2
One hour access (0.3 mA shock)0.20.30.60.00.4-0.40.60.80.70.40.50.6
One hour access (shock baseline)0.20.21.1-0.00.3-0.5-0.20.21.10.50.30.1
Number of responses in last shaping day2.93.06.11.2-2.02.5-1.1-1.9-2.3-0.2-2.1-0.8
Context. condit. distance diff. score0.81.01.71.1-1.11.1-0.7-0.7-1.3-0.9-1.1-0.9
Locomotion velocity, session 10.20.20.9-0.5-0.50.4-0.1-1.0-0.50.2-0.5-0.0
Locomotion distance, session 10.71.04.1-0.10.8-1.5-0.60.62.0-0.20.8-0.3
Locomotion velocity, session 20.40.41.0-0.1-0.70.3-0.9-1.0-0.3-0.3-0.7-0.8
Locomotion distance, session 20.60.83.0-1.20.8-1.3-0.5-0.11.70.60.8-0.0
Locomotion velocity, session 32.12.45.51.8-0.2-1.1-2.30.71.1-2.4-0.2-2.2
Locomotion distance, session 32.42.65.30.81.4-2.3-1.02.12.3-1.31.4-0.9
Stereotopy head waving bouts, day 30.60.83.11.8-0.70.5-0.40.5-0.5-1.2-0.7-0.7
Stereotopy head waving duration, day 30.81.02.21.5-1.01.20.1-0.1-1.5-1.0-1.0-0.4
Locomotion velocity, session 70.20.20.40.50.1-0.5-0.60.30.5-0.50.1-0.6
Locomotion distance, session 70.20.31.20.5-0.2-0.3-1.1-0.00.3-0.6-0.2-0.9
Stereotopy head waving bouts, day 71.82.05.92.1-0.5-0.3-1.70.5-0.0-2.4-0.5-2.0
Stereotopy head waving duration, day 71.61.95.61.9-0.7-0.1-1.70.2-0.1-2.4-0.7-2.0
Locomotion velocity, session 80.91.02.80.8-0.6-0.3-1.7-0.40.1-1.5-0.6-1.6
Locomotion distance, session 80.60.92.90.7-0.5-0.3-1.7-0.50.5-1.1-0.5-1.4
Degree of sensitization distance1.51.53.3-0.3-1.31.80.2-1.7-1.70.7-1.30.2
Degree of sensitization stereotypy1.41.54.31.6-0.4-0.3-1.60.20.0-2.1-0.4-1.8
Condit. Reinf. active minus inactive responses0.40.52.1-1.40.3-0.5-0.2-0.80.60.70.30.1
Condit. Reinf. active-inactive response ratio0.40.41.5-0.4-0.40.90.4-0.6-1.20.3-0.40.3
Condit. Reinf. active responses0.50.61.4-1.10.1-0.8-1.2-1.11.00.20.1-0.7
Condit. Reinf. inactive responses0.70.82.3-0.40.1-1.1-1.5-0.51.5-0.30.1-1.0
Incentive salience index mean0.50.62.1-0.5-0.70.3-1.1-1.40.30.2-0.7-0.6
Condit. Reinf. lever presses1.01.42.80.8-1.50.9-1.7-1.50.2-0.4-1.5-1.2
Time in familiar zone, hab. session 11.41.32.00.8-1.41.2-1.3-1.2-0.9-0.6-1.4-1.2
Time in novel zone, hab. session 11.31.23.5-1.21.0-0.41.90.8-0.10.91.01.5
Total zone transitions, hab. session 12.02.88.4-1.02.0-2.40.01.42.90.62.00.4
Total locomotion distance, hab. session 13.04.210.9-1.42.5-3.00.41.73.30.82.50.8
Locomotion velocity, hab. session 11.92.88.5-0.91.9-2.50.01.42.90.41.90.4
Time in familiar zone, hab. session 20.30.30.90.4-0.50.6-0.4-0.3-1.0-0.6-0.5-0.5
Time in novel zone, hab. session 20.00.00.10.1-0.10.20.40.1-0.10.1-0.10.3
Total zone transitions, hab. session 21.62.17.0-1.41.4-2.1-0.40.42.60.71.40.2
Total locomotion distance, hab. session 22.33.09.6-1.81.8-2.4-0.00.63.11.21.80.6
Locomotion velocity, hab. session 22.43.210.6-1.61.9-2.40.20.83.31.31.90.8
Novel to familiar place preference ratio0.20.20.6-0.3-0.50.8-0.0-0.7-0.60.2-0.50.0
Novelty place preference0.70.71.7-0.1-1.01.3-0.1-1.2-1.20.2-1.0-0.1
Time in novel zone, NPP test1.31.43.40.1-1.31.8-0.2-1.4-1.8-0.1-1.3-0.3
Total zone transitions, NPP test0.50.72.5-0.70.8-1.3-0.70.21.60.00.8-0.3
Total locomotion distance, NPP test0.91.35.1-1.01.0-1.7-0.60.32.30.41.0-0.1
Locomotion velocity, NPP test1.72.49.5-0.91.5-2.4-0.70.83.10.31.5-0.1
Pavlov. Cond. lever latency0.91.23.6-0.61.2-0.51.91.3-0.50.41.21.3
Pavlov. Cond. magazine entry latency0.40.52.2-0.50.1-0.3-0.1-0.31.51.20.10.4
Pavlov. Cond. change in total contacts0.30.41.2-0.7-0.1-0.1-0.3-0.70.91.1-0.10.2
Pavlov. Cond. index score0.40.52.1-0.2-0.2-0.3-1.0-0.61.50.7-0.2-0.3
Pavlov. Cond. latency score0.30.41.7-0.1-0.3-0.2-1.1-0.71.30.5-0.3-0.5
Pavlov. Cond. lever contacts0.50.51.50.1-0.80.4-1.2-1.00.50.1-0.8-0.7
Pavlov. Cond. magazine entry number0.40.52.70.5-0.40.70.3-0.0-1.7-0.9-0.4-0.3
Pavlov. Cond. intertrial magazine entries0.60.71.80.10.2-0.8-1.3-0.10.1-1.30.2-1.3
Pavlov. Cond. lever-magazine prob. diff.0.40.52.0-0.2-0.3-0.2-1.0-0.71.40.7-0.3-0.4
Pavlov. Cond. response bias0.30.31.5-0.5-0.0-0.3-0.5-0.51.20.8-0.0-0.0
Bone: apparent density0.10.20.50.7-0.1-0.1-0.50.10.2-0.7-0.1-0.5
Bone surface1.62.94.41.6-1.71.2-2.1-1.4-1.2-1.8-1.7-2.1
Bone volume0.71.21.51.0-1.20.9-1.2-1.1-0.9-1.1-1.2-1.2
Bone: connectivity density0.91.43.70.71.0-1.6-0.81.41.9-0.81.0-0.6
Bone: cortical apparent density2.33.04.5-1.42.0-1.52.11.81.21.32.01.9
Bone: cortical area0.50.72.11.1-0.81.30.1-0.3-1.5-0.5-0.8-0.2
Bone: cortical porosity0.10.10.30.20.1-0.10.40.40.50.40.10.5
Bone: cortical porosity0.20.30.90.60.3-0.50.10.81.00.00.30.1
Bone: cortical thickness0.81.43.1-0.11.4-0.51.81.60.30.61.41.5
Bone: cortical thickness0.60.72.6-0.20.30.51.60.6-0.60.70.31.3
Bone: cortical tissue density2.12.84.3-1.41.9-1.42.11.71.11.31.91.9
Bone: elastic displacement0.70.71.3-1.20.8-0.51.10.30.51.10.81.1
Bone: elastic work0.20.20.5-0.40.5-0.20.70.30.00.40.50.7
Bone: endosteal estimation3.88.112.02.0-3.52.9-2.7-3.1-2.9-2.0-3.5-2.7
Bone: endosteal perimeter2.04.26.31.3-2.52.2-1.9-2.4-2.1-1.1-2.5-1.8
Bone: final force0.20.31.00.2-0.50.9-0.1-0.8-1.0-0.0-0.5-0.2
Bone: final moment0.20.31.00.0-0.30.80.3-0.6-1.00.2-0.30.2
Bone: marrow area3.88.212.22.0-3.53.0-2.6-3.1-3.0-1.9-3.5-2.6
Bone: maximum diameter5.09.214.71.9-3.73.7-2.1-3.4-3.8-1.7-3.7-2.3
Bone: maximum force0.50.91.80.5-1.11.3-0.5-1.3-1.4-0.3-1.1-0.5
Bone: maximum moment0.40.71.70.4-0.91.3-0.1-1.0-1.3-0.1-0.9-0.1
Bone: minimum diameter0.30.61.60.1-0.61.30.5-0.8-1.30.4-0.60.4
Bone: periosteal estimation2.65.48.41.6-2.82.7-1.7-2.5-2.9-1.5-2.8-1.8
Bone: periosteal perimeter1.52.63.21.5-1.71.6-1.5-1.3-1.8-1.5-1.7-1.6
Bone: post-yield work2.63.64.91.3-2.21.8-2.0-2.0-1.8-1.5-2.2-2.0
Bone: stiffness0.10.10.30.2-0.1-0.0-0.5-0.2-0.2-0.5-0.1-0.6
Bone: tissue strength0.20.20.60.00.5-0.30.60.80.10.00.50.4
Bone: trabecular number0.40.71.41.0-0.1-0.6-1.20.31.0-1.0-0.1-1.0
Bone: trabecular spacing2.63.44.2-1.92.1-1.61.91.41.61.92.12.0
Bone: trabecular thickness0.40.41.40.2-0.51.00.7-0.4-1.20.2-0.50.5
Bone: trabecular tissue density0.70.92.4-0.90.30.61.60.0-1.11.20.31.4
Breakpoint value in progressive ratio session0.80.91.30.7-1.00.9-1.1-1.1-0.8-0.7-0.9-1.1
Distance traveled before self-admin1.92.13.71.6-1.21.0-1.9-0.9-1.1-1.8-1.3-1.8
Distance traveled after self-admin2.83.14.71.2-2.12.2-1.3-1.9-2.1-1.4-2.0-1.3
Delta time in closed arm before/after self-admin1.11.02.3-1.20.7-0.11.50.4-0.01.40.81.5
Delta time in open arm before/after self-admin2.32.25.12.00.9-1.6-0.72.31.3-1.80.8-1.2
Diff in mean of infusions in LGA sessions2.83.25.01.7-2.12.2-1.4-1.9-1.9-1.1-2.0-1.4
Extinction: sum of active levers before priming0.40.41.41.2-0.20.2-0.90.4-0.4-0.7-0.3-0.8
Active lever presses in extinction session 60.80.81.71.0-0.80.5-1.0-0.5-0.5-1.3-0.8-1.1
Delta distance traveled before/after self-admin0.80.91.9-0.6-0.81.40.9-1.2-1.30.4-0.70.7
Delta ambulatory time before/after self-admin0.91.02.6-0.2-1.01.60.9-1.0-1.60.2-0.90.6
Time in closed arm before self-admin0.60.61.20.5-1.10.8-0.8-0.9-0.6-0.4-1.1-0.7
Time in closed arm after self-admin0.40.41.3-1.00.2-0.10.80.10.21.10.31.0
Time in open arm before self-admin1.11.23.30.2-1.11.6-0.5-1.5-1.8-0.1-1.1-0.3
Time in open arm after self-admin1.71.95.52.3-0.50.2-1.50.5-0.5-2.3-0.5-1.8
Sum of active levers in priming session hrs 5-60.50.51.20.8-0.70.8-0.3-0.3-1.1-1.0-0.6-0.6
Time to tail flick, vehicle, before self-admin0.60.61.50.9-0.50.2-1.0-0.2-0.2-1.2-0.4-1.2
Time to tail flick, vehicle, after self-admin4.04.25.32.2-2.11.7-2.3-1.4-2.2-2.0-2.2-2.3
Time to tail flick, test, before self-admin0.20.20.7-0.8-0.0-0.1-0.0-0.60.20.60.00.3
Time to tail flick, test, after self-admin0.80.81.90.2-1.11.0-0.7-1.4-0.9-0.6-1.1-0.6
Delta time to tail flick, vehicle, before/after SA1.01.01.50.9-1.20.8-1.1-0.9-1.1-0.8-1.2-1.0
Delta time to tail flick, test, before/after SA1.71.62.71.4-1.31.4-0.9-0.8-1.6-1.3-1.3-1.1
Ambulatory time before self-admin0.70.72.31.1-0.50.2-1.5-0.3-0.1-1.0-0.6-1.2
Ambulatory time after self-admin2.52.84.71.4-1.92.1-1.1-1.6-2.2-1.3-1.9-1.2
Total heroin consumption1.51.82.70.7-1.51.5-1.1-1.6-1.6-1.1-1.5-1.1
Area under the delay curve0.91.03.5-0.1-0.91.2-0.6-1.9-1.2-0.1-1.0-0.5
Delay disc. indifference point, 0s delay0.40.40.9-0.80.5-0.8-0.5-0.30.90.50.6-0.3
Delay disc. indifference point, 16s delay0.10.10.5-0.10.00.40.1-0.4-0.70.3-0.00.2
Delay disc. indifference point, 2s delay0.30.31.3-0.7-0.20.60.1-1.1-0.70.5-0.20.1
Delay disc. indifference point, 24s delay0.00.00.1-0.30.20.0-0.0-0.4-0.10.10.10.1
Delay disc. indifference point, 4s delay0.70.81.70.4-0.80.7-1.0-1.3-0.8-0.8-0.8-1.0
Delay disc. indifference point, 8s delay2.02.16.4-0.0-1.51.7-1.0-2.5-1.6-0.3-1.6-0.8
Delay discount exponential model param1.11.24.00.11.0-1.30.72.01.30.21.10.6
Delay discount hyperbolic model param1.01.03.40.11.0-1.20.61.91.30.21.00.5
Fecal boli incidents, locomotor time 10.91.03.4-0.8-0.91.1-0.2-1.9-0.61.0-1.00.1
Change in fecal boli incidents, locomotor task2.42.26.32.3-1.00.5-1.20.8-1.2-2.5-1.0-1.6
Time >=10cm from walls, locomotor time 10.70.70.90.9-0.90.7-1.0-0.8-0.4-0.7-1.0-0.8
Bouts of movement, locomotor time 10.10.10.6-0.60.10.1-0.0-0.80.10.5-0.10.2
Total resting periods, locomotor time 10.10.10.5-0.4-0.00.30.0-0.7-0.20.4-0.20.1
Rest time, locomotor task time 11.01.14.5-0.3-0.81.50.5-1.0-2.10.5-0.80.3
Distance moved, locomotor task time 10.91.03.0-0.41.0-1.50.20.91.70.11.20.2
Vertical activity count, locomotor time 10.40.41.5-0.10.6-1.0-0.00.51.2-0.00.80.0
Time >=10cm from walls, locomotor time 20.30.30.8-0.3-0.40.60.8-0.1-0.50.9-0.30.8
Bouts of movement, locomotor time 21.51.63.3-1.81.2-1.10.90.31.51.71.11.3
Total resting periods, locomotor time 21.01.12.3-1.51.0-0.90.70.11.21.40.91.0
Rest time, locomotor task time 20.60.71.5-0.40.9-0.31.20.90.11.00.91.1
Distance moved, locomotor task time 20.20.30.8-0.30.2-0.8-0.6-0.10.9-0.20.3-0.5
Vertical activity count, locomotor time 20.00.00.1-0.1-0.30.1-0.1-0.40.00.1-0.2-0.1
Weight adjusted by age1.71.94.90.1-1.61.4-1.5-2.2-1.30.1-1.6-1.0
Seeking ratio, delayed vs. immediate footshock3.84.47.41.4-2.31.7-2.7-2.2-1.5-1.7-2.4-2.4
Locomotion in novel chamber0.10.10.2-0.10.2-0.20.40.5-0.10.40.10.4
Locomotion in novel chamber post-restriction0.30.30.6-0.70.5-0.40.80.50.50.20.50.7
Progressive ratio0.80.92.5-1.3-0.91.10.2-1.6-0.71.0-0.80.5
Food seeking constrained by brief footshock3.44.27.60.8-2.32.3-1.4-2.6-2.8-1.5-2.3-1.6
Seeking ratio, punishment vs. effort0.81.02.71.5-0.50.2-1.1-0.2-0.8-1.6-0.6-1.4
Run reversals in cocaine runway, females0.60.62.0-0.50.4-0.31.40.80.10.90.41.1
Run reversals in cocaine runway, males0.60.61.80.2-0.60.1-1.3-1.0-0.1-0.7-0.6-1.2
Latency to leave start box in cocaine runway0.50.51.21.0-0.50.0-1.10.00.2-1.0-0.6-1.0
Latency to leave start box in cocaine runway, F0.10.10.30.2-0.40.1-0.6-0.50.1-0.2-0.5-0.4
Latency to leave start box in cocaine runway, M0.50.41.00.50.3-0.9-0.60.91.0-0.40.3-0.5
Cd content in liver0.20.20.8-0.90.2-0.5-0.3-0.60.50.50.2-0.0
Co content in liver1.72.05.0-2.20.8-0.31.6-0.50.52.20.81.8
Cu content in liver0.91.12.4-1.40.9-0.31.30.20.31.50.91.5
Fe content in liver2.42.97.62.3-0.6-0.5-2.30.40.4-2.8-0.6-2.4
K content in liver0.10.10.20.0-0.0-0.1-0.4-0.1-0.2-0.3-0.0-0.4
Mg content in liver0.40.41.2-0.2-0.70.7-0.3-1.1-1.0-0.1-0.7-0.4
Mn content in liver0.20.30.70.7-0.40.90.50.2-0.60.2-0.40.4
Na content in liver1.11.12.71.5-0.6-0.0-1.60.00.2-1.4-0.6-1.5
Rb content in liver0.60.71.60.3-0.60.3-1.3-0.9-0.7-1.1-0.6-1.2
Se content in liver0.40.51.70.30.8-0.80.21.31.0-0.00.80.3
Sr content in liver0.20.20.40.1-0.50.2-0.6-0.60.30.1-0.5-0.4
Zn content in liver0.70.82.1-1.20.40.11.3-0.1-0.11.50.41.3