Hub : Genes

Igfbp4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS ENSRNOT00000014153 0.02 0.01 8.0e-03 0 -0 0 -0 1.4e-01 5.5e-01 3.2e-01 5.8e-01
2 Adipose gene expression ENSRNOG00000010635 0.54 0.13 0.0e+00 0.46 0.14 0.47 0.41 1.8e-56 1.2e-15 1.5e-57 3.7e-48
3 Adipose mRNA stability ENSRNOG00000010635 0.32 0.11 0.0e+00 0.21 0.22 0.25 0.24 1.7e-22 9.5e-24 3.8e-27 6.3e-26
4 Brain gene expression ENSRNOG00000010635 0.23 0.1 1.7e-15 0.17 0.16 0.14 0.16 3.3e-15 2.0e-14 4.9e-13 3.0e-14
5 Brain mRNA stability ENSRNOG00000010635 0.03 0.03 5.7e-03 0.02 0.02 0.01 0.02 7.2e-03 7.3e-03 2.4e-02 9.5e-03
6 IL mRNA stability ENSRNOG00000010635 0.16 0.11 4.3e-03 0.02 0.05 0.01 0.03 9.3e-02 2.2e-02 1.4e-01 8.1e-02
7 Liver mRNA stability ENSRNOG00000010635 0.22 0.09 0.0e+00 0.16 0.17 0.16 0.17 1.2e-17 4.4e-18 6.1e-18 2.3e-18
8 NAcc mRNA stability ENSRNOG00000010635 0.03 0.02 6.6e-03 0.03 0.02 0.02 0.02 3.0e-03 1.3e-02 7.6e-03 9.8e-03
9 OFC gene expression ENSRNOG00000010635 0.52 0.22 1.8e-08 0.27 0.24 0.3 0.2 4.3e-07 1.7e-06 6.8e-08 1.9e-05
10 PL gene expression ENSRNOG00000010635 0.08 0.05 8.7e-06 0.04 0.06 0.05 0.05 3.3e-04 3.2e-05 1.5e-04 1.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail2.47.911.5-3.0-2.9-1.73.4-2.4-2.7-2.7-3.22.82.7
BMI without tail0.20.51.4-1.2-0.6-0.40.6-0.5-0.6-0.7-1.10.60.6
Body weight4.519.027.5-4.6-4.8-3.15.2-3.6-4.3-4.3-4.84.44.2
Epididymis fat weight0.10.20.7-0.2-0.10.20.5-0.7-0.1-0.1-0.20.40.9
Glucose0.00.00.1-0.2-0.10.20.20.30.20.10.1-0.10.0
Heart weight3.75.26.4-2.4-2.5-2.12.3-1.9-2.5-2.3-2.22.52.1
Left kidney weight0.51.54.3-0.6-1.7-1.91.30.6-1.2-2.1-0.60.7-0.0
Right kidney weight0.10.20.5-0.6-0.5-0.10.70.60.0-0.6-0.2-0.4-0.5
Tail length0.10.30.6-0.7-0.5-0.70.2-0.1-0.5-0.8-0.50.3-0.1
Length with tail1.55.68.3-2.2-2.9-2.62.7-1.4-2.5-2.8-2.02.31.7
Length without tail2.24.99.6-2.0-2.7-1.93.1-1.5-2.2-2.3-1.92.22.0
Liver weight, left0.00.10.2-0.00.30.3-0.20.40.30.3-0.0-0.3-0.1
Liver weight, right1.32.14.90.61.00.9-0.92.21.60.91.0-2.1-2.1
Parametrial fat weight1.73.25.81.31.92.2-1.41.32.22.41.4-2.1-1.3
Retroperitoneal fat weight0.00.20.5-0.7-0.4-0.00.50.1-0.1-0.2-0.70.20.3
Intraocular pressure3.54.97.0-2.4-2.2-1.72.0-2.6-2.4-2.2-2.32.21.9
Extensor digitorum longus weight8.032.341.0-5.5-6.3-5.65.5-4.4-6.3-6.4-5.26.15.1
Soleus weight0.30.82.1-1.5-0.40.71.1-0.9-0.1-0.1-1.30.31.2
Tibialis anterior weight1.34.67.7-2.8-2.4-1.52.6-1.4-2.1-2.3-2.41.81.7
Tibia length1.74.98.7-2.8-2.5-1.12.9-1.6-2.0-2.0-2.52.12.0
Number of licking bursts0.20.20.7-0.00.30.90.2-0.40.40.60.2-0.00.6
Food consumed during 24 hour testing period0.80.91.2-1.0-1.1-0.81.0-1.0-0.9-0.8-1.11.00.9
Times rat made contact with spout0.50.51.60.50.91.0-0.7-0.40.81.30.2-0.5-0.1
Mean time between licks in bursts1.92.76.1-1.4-1.3-0.91.5-2.2-1.5-1.3-1.21.92.5
Mean num. licks in bursts0.10.20.70.30.3-0.1-0.60.20.20.30.0-0.4-0.9
Std. dev. time between licks in bursts0.20.21.1-0.3-0.10.30.4-0.5-0.2-0.1-0.10.51.1
Water consumed over 24 hours0.20.30.7-0.4-0.5-0.30.2-0.8-0.40.1-0.60.60.9
Indifference point 0 sec1.42.34.62.11.90.9-2.10.91.41.51.6-1.2-0.8
Indifference point AUC0.00.00.1-0.0-0.20.00.30.2-0.1-0.2-0.10.20.3
Indifference point function ln k0.10.10.60.2-0.1-0.8-0.30.4-0.1-0.40.30.0-0.5
Indifference point function log k0.10.10.60.2-0.1-0.8-0.30.4-0.1-0.40.30.0-0.5
Delay discounting total patch changes 0 sec1.01.63.41.91.60.7-1.80.61.11.21.3-0.8-0.5
Delay discounting total patch changes 12 sec4.15.48.12.22.82.7-2.51.42.72.81.9-2.3-1.2
Delay discounting total patch changes 18 sec0.30.40.80.80.90.6-0.90.40.70.70.5-0.30.2
Delay discounting total patch changes 24 sec1.41.82.21.41.41.1-1.41.41.41.51.4-1.3-0.9
Delay discounting total patch changes 6 sec1.62.53.61.91.81.3-1.91.11.61.71.7-1.4-1.0
Delay discounting time to switch 0 sec0.10.10.40.10.40.6-0.4-0.10.50.40.1-0.6-0.2
Delay discounting water rate 0 sec0.10.10.50.70.30.0-0.20.30.20.30.6-0.0-0.2
Delay discounting water rate 12 sec0.00.10.30.4-0.0-0.40.00.30.0-0.10.5-0.0-0.1
Delay discounting water rate 18 sec0.50.71.30.40.80.9-0.51.11.11.00.7-1.0-0.6
Delay discounting water rate 24 sec0.40.61.30.70.90.7-0.80.70.91.10.5-0.6-0.4
Delay discounting water rate 6 sec1.62.43.21.31.71.4-1.41.61.71.81.4-1.6-1.4
Locomotor activity0.50.82.20.51.01.5-0.50.41.21.2-0.0-0.8-0.2
Locomotor testing distance1.83.04.51.92.11.9-1.71.12.02.01.4-1.6-1.3
Locomotor testing rearing5.99.312.03.23.32.3-3.52.83.23.03.1-3.1-3.0
Light reinforcement 12.75.06.91.92.62.3-2.41.92.52.52.0-2.2-1.8
Light reinforcement 20.50.62.00.10.81.4-0.40.21.01.00.2-1.0-0.5
Reaction time number correct0.60.91.8-0.9-1.0-0.61.1-0.8-1.0-0.6-0.81.21.3
Reaction time mean minus median0.60.81.6-0.8-0.5-0.40.4-1.3-0.9-0.8-1.01.11.1
Reaction time mean minus median AUC0.10.20.6-0.3-0.00.1-0.0-0.8-0.4-0.2-0.50.60.6
Reaction time num false alarms0.40.52.0-0.00.81.4-0.2-0.10.81.2-0.1-0.30.4
Reaction time num false alarms AUC0.30.51.8-0.00.81.4-0.1-0.40.61.0-0.4-0.10.8
Reaction time trials correct on left0.60.91.8-0.9-1.0-0.61.1-0.8-1.0-0.6-0.81.21.3
Reaction time trials on left0.60.91.8-0.9-1.0-0.61.1-0.8-1.0-0.5-0.81.21.3
Reaction time mean0.40.51.20.60.70.2-1.00.80.50.30.6-0.7-1.1
Reaction time mean AUC0.50.61.40.70.70.2-1.01.00.60.30.7-0.7-1.2
Median of all reaction times1.41.93.31.21.40.7-1.71.61.31.11.3-1.4-1.8
Reaction time omissions0.91.22.00.71.41.4-1.10.61.31.40.4-1.1-0.9
Reaction time false alarm rate0.50.72.10.51.11.5-0.60.21.01.20.2-0.7-0.0
Reaction time premature initiation rate1.52.04.80.90.90.8-0.62.21.30.91.8-1.7-2.1
Reaction time premature initiations0.30.52.00.10.00.20.21.40.50.31.1-0.7-1.0
Std. dev. reaction times0.10.10.2-0.10.10.1-0.1-0.5-0.2-0.3-0.50.30.3
Reaction time trials completed0.60.91.8-0.9-1.0-0.61.1-0.8-1.0-0.5-0.81.21.3
Reaction time trials AUC0.60.81.8-0.7-0.9-0.60.9-0.8-1.0-0.5-0.71.21.3
Social response proportion0.30.30.7-0.6-0.9-0.70.7-0.2-0.6-0.7-0.50.50.3
Social responses0.10.10.2-0.3-0.00.40.4-0.20.20.1-0.5-0.10.2
Social time0.60.82.6-1.0-0.20.90.8-1.6-0.20.3-1.00.51.2
Conditioned locomotion0.30.40.90.40.50.1-0.70.90.50.40.5-0.6-0.8
Cocaine response after cond. corrected0.60.62.00.10.71.4-0.00.41.01.1-0.0-1.0-0.7
Cocaine response after cond. not corrected0.70.72.40.20.81.5-0.10.61.21.1-0.0-1.0-0.7
Cocaine response before conditioning0.10.10.30.40.30.0-0.60.50.20.20.2-0.0-0.0
Saline control response0.30.41.0-1.0-0.6-0.11.0-0.3-0.3-0.4-0.80.40.5
Condit. Reinf. active minus inactive responses0.81.01.90.81.31.4-0.90.31.21.30.7-1.0-0.3
Condit. Reinf. active-inactive response ratio0.60.71.90.41.11.4-0.6-0.01.01.30.4-0.7-0.0
Condit. Reinf. active responses1.31.93.71.21.71.9-1.10.41.71.81.0-1.3-0.5
Condit. Reinf. inactive responses1.51.93.01.41.61.7-1.10.71.71.71.2-1.5-0.9
Condit. Reinf. lever presses0.20.30.70.70.50.2-0.50.60.50.30.8-0.5-0.4
Condit. Reinf. lever reinforcers received1.52.13.11.51.81.8-1.30.71.81.81.3-1.5-0.8
Pavlov. Cond. lever latency0.30.40.6-0.8-0.7-0.60.5-0.1-0.7-0.8-0.80.60.2
Pavlov. Cond. magazine entry latency0.10.10.2-0.3-0.30.00.3-0.4-0.20.0-0.50.30.3
Pavlov. Cond. change in total contacts0.40.61.31.10.90.5-1.00.30.80.81.0-0.6-0.4
Pavlov. Cond. index score0.10.10.30.20.30.5-0.1-0.20.40.50.1-0.20.1
Pavlov. Cond. latency score0.10.10.20.00.20.40.0-0.40.20.4-0.1-0.00.3
Pavlov. Cond. lever contacts0.50.71.30.91.01.1-0.50.21.11.10.9-0.8-0.3
Pavlov. Cond. magazine entry number0.00.00.1-0.0-0.0-0.2-0.10.0-0.1-0.30.10.10.1
Pavlov. Cond. intertrial magazine entries0.91.23.0-0.4-1.1-1.70.4-0.5-1.4-1.7-0.41.20.7
Pavlov. Cond. lever-magazine prob. diff.0.00.10.20.10.20.40.0-0.30.30.40.0-0.10.2
Pavlov. Cond. response bias0.81.21.91.11.21.3-0.80.51.31.41.0-1.1-0.6
Conditioned reinforcement - actives0.40.40.80.70.80.4-0.8-0.30.70.90.6-0.5-0.3
Conditioned reinforcement - inactives1.61.83.71.51.81.3-1.90.11.21.71.1-1.1-0.8
Conditioned locomotion0.20.20.50.10.50.6-0.5-0.50.60.7-0.0-0.40.2
Intermittent access intake day 1-15 change0.90.91.40.80.90.6-1.01.20.90.91.0-0.8-1.1
Intermittent access intake escalation1.01.01.70.90.90.6-1.01.31.01.01.0-0.9-1.2
Intermittent access intake escalation 20.10.10.20.00.20.3-0.30.30.20.40.1-0.2-0.3
Intermitt. access day 1 inactive lever presses3.33.65.11.61.81.6-1.62.32.01.81.7-2.2-2.3
Intermitt. access day 15 inactive lever presses4.44.95.82.32.41.7-2.41.72.32.22.2-2.3-2.4
Intermitt. access escalation Index1.41.22.3-1.2-1.5-1.11.50.2-1.1-1.5-0.90.80.7
Intermittent access day 1 total infusions0.20.20.40.20.50.6-0.50.10.50.60.2-0.5-0.3
Intermittent access day 15 total infusions1.21.42.51.01.00.7-1.21.51.11.01.1-1.2-1.6
Intermittent access terminal intake (last 3 days)1.11.21.80.91.10.9-1.21.21.11.20.9-1.2-1.3
Intermittent access total infusions0.50.61.00.50.70.6-0.80.90.70.80.6-0.8-1.0
Intermittent access day 1 locomotion0.10.10.20.40.40.3-0.5-0.50.20.40.1-0.10.2
Intermittent access day 15 total locomotion0.30.41.6-0.00.50.6-0.6-1.30.30.8-0.3-0.00.4
Intermittent access total locomotion0.50.51.10.81.00.6-1.1-0.20.70.90.6-0.6-0.5
Intermittent access standard deviation3.13.34.62.02.11.4-2.11.51.62.01.9-1.6-1.8
Cocaine induced anxiety1.51.73.7-1.9-1.6-0.51.9-0.4-1.0-1.3-1.70.80.8
Post-drug Anxiety0.20.20.5-0.6-0.6-0.10.70.4-0.2-0.4-0.50.0-0.2
Baseline Anxiety1.01.12.41.61.20.4-1.40.40.71.01.3-0.7-0.9
Lifetime Intake0.80.81.60.70.80.6-0.91.30.80.80.8-1.0-1.3
Incentive Sensitization - Responses1.01.02.10.91.41.2-1.5-1.00.91.40.5-0.50.0
Incentive Sensitization - Breakpoint1.01.01.90.81.31.2-1.4-0.90.91.40.5-0.50.0
Progressive ratio test 1 active lever presses0.60.61.00.80.70.5-0.70.90.80.60.8-0.9-1.0
Progressive ratio test 1 breakpoint0.60.61.00.80.70.5-0.61.00.70.60.8-0.9-1.0
Progressive ratio test 1 inactive lever presses2.42.63.31.71.61.0-1.61.81.51.41.8-1.7-1.8
Progressive ratio test 2 active lever presses1.21.22.11.21.41.0-1.40.41.11.31.1-1.0-0.9
Progressive ratio test 2 breakpoint0.80.91.51.11.20.8-1.20.41.01.11.0-0.8-0.8
Progressive ratio test 2 inactive lever presses0.60.71.40.81.10.9-1.20.20.81.10.7-0.8-0.7
Total sessions with >9 infusions1.11.22.41.20.90.4-1.11.60.90.91.3-1.0-1.4
Short access day 1 total inactive lever presses2.62.94.21.61.91.6-2.01.31.71.91.5-1.8-1.8
Short access day 10 total inactive lever presses0.10.10.5-0.10.10.2-0.20.70.10.20.0-0.2-0.3
Short access day 1 total infusions1.92.04.41.41.10.6-1.22.11.21.01.6-1.5-2.0
Short access day 10 total infusions0.50.50.80.40.70.9-0.70.70.80.70.4-0.9-0.7
Short access total infusions1.31.43.61.10.90.5-1.01.91.00.81.3-1.2-1.7
Short access day 1 locomotion4.14.35.42.22.31.8-2.31.72.22.12.1-2.2-1.9
Short access day 10 total locomotion0.70.81.50.71.21.2-1.1-0.71.01.10.4-0.8-0.1
Short access total locomotion0.50.51.00.90.90.4-1.00.10.50.70.8-0.4-0.4
Compulsive drug intake0.70.71.80.3-0.5-1.40.2-0.6-1.1-0.90.11.30.6
One hour access (0.3 mA shock)0.00.00.10.20.1-0.1-0.20.20.10.10.3-0.1-0.3
One hour access (shock baseline)0.50.61.20.30.71.0-0.60.81.00.90.4-1.1-0.9
Number of responses in last shaping day1.11.22.41.51.10.3-1.01.10.70.71.5-0.7-1.3
Context. condit. distance diff. score0.91.14.3-0.3-1.4-2.10.60.3-1.4-1.2-0.21.0-0.1
Locomotion velocity, session 10.40.50.8-0.9-0.7-0.10.9-0.6-0.5-0.5-0.90.50.7
Locomotion distance, session 12.33.04.9-2.1-1.8-0.72.2-1.6-1.5-1.2-2.21.61.9
Locomotion velocity, session 20.10.10.30.1-0.3-0.30.10.3-0.2-0.60.10.10.1
Locomotion distance, session 20.20.30.8-0.7-0.30.60.9-0.7-0.00.0-0.80.20.8
Locomotion velocity, session 30.30.31.00.90.4-0.1-0.70.60.30.11.0-0.4-0.5
Locomotion distance, session 30.10.10.3-0.2-0.3-0.20.3-0.5-0.4-0.3-0.30.40.5
Stereotopy head waving bouts, day 32.63.24.91.61.71.0-1.82.11.81.41.8-2.0-2.2
Stereotopy head waving duration, day 30.30.31.30.30.20.0-0.21.10.40.10.4-0.6-0.9
Locomotion velocity, session 71.31.42.9-1.2-1.1-0.41.4-1.3-1.1-0.9-1.11.31.7
Locomotion distance, session 70.81.12.5-0.9-0.8-0.50.8-1.5-1.0-0.7-0.91.21.6
Stereotopy head waving bouts, day 70.60.71.30.60.70.7-0.51.11.00.80.7-1.2-1.1
Stereotopy head waving duration, day 70.60.71.70.50.60.6-0.41.30.90.70.6-1.2-1.3
Locomotion velocity, session 85.97.09.8-2.5-3.1-2.82.8-1.7-3.1-2.9-2.42.82.0
Locomotion distance, session 80.81.22.0-1.0-1.4-1.11.4-0.7-1.2-1.1-0.91.10.9
Degree of sensitization distance1.61.62.2-1.2-1.3-1.21.1-1.3-1.4-1.2-1.11.51.4
Degree of sensitization stereotypy0.91.01.60.70.91.1-0.60.91.11.10.8-1.3-1.1
Condit. Reinf. active minus inactive responses1.51.62.51.61.30.5-1.51.21.10.91.5-1.2-1.6
Condit. Reinf. active-inactive response ratio1.92.03.31.81.30.2-1.81.61.10.71.8-1.3-1.7
Condit. Reinf. active responses1.31.63.01.71.30.6-1.51.11.00.91.6-1.1-1.4
Condit. Reinf. inactive responses0.10.10.30.50.30.6-0.1-0.00.30.60.3-0.2-0.1
Incentive salience index mean2.02.43.61.91.81.1-1.81.11.51.41.8-1.5-1.4
Condit. Reinf. lever presses0.60.81.31.11.21.1-1.00.21.01.01.0-0.7-0.2
Time in familiar zone, hab. session 10.30.31.0-0.70.11.00.50.20.70.7-0.5-0.50.1
Time in novel zone, hab. session 10.90.92.91.70.9-0.2-1.40.30.20.51.5-0.4-0.8
Total zone transitions, hab. session 11.31.82.7-1.2-1.7-1.51.4-1.0-1.6-1.3-1.41.40.9
Total locomotion distance, hab. session 10.10.10.30.3-0.1-0.4-0.20.5-0.00.20.3-0.1-0.6
Locomotion velocity, hab. session 10.10.10.4-0.2-0.5-0.70.30.3-0.4-0.4-0.30.2-0.3
Time in familiar zone, hab. session 20.70.71.40.10.50.8-0.31.21.01.00.2-1.1-1.2
Time in novel zone, hab. session 20.30.31.01.00.70.2-0.7-0.30.20.20.9-0.10.2
Total zone transitions, hab. session 21.31.72.3-1.4-1.3-0.81.3-1.5-1.3-0.9-1.51.41.3
Total locomotion distance, hab. session 20.50.61.3-1.0-0.7-0.10.8-1.1-0.6-0.2-1.00.80.9
Locomotion velocity, hab. session 20.70.91.6-1.2-0.9-0.31.0-1.1-0.8-0.4-1.31.01.0
Novel to familiar place preference ratio0.50.51.6-0.3-0.8-1.20.40.2-0.8-1.3-0.30.4-0.2
Novelty place preference0.50.51.7-0.1-0.7-1.30.20.3-0.7-1.3-0.10.4-0.3
Time in novel zone, NPP test0.20.30.90.2-0.3-0.9-0.10.6-0.4-0.90.20.0-0.6
Total zone transitions, NPP test1.31.93.4-1.7-1.2-0.21.4-1.8-1.0-0.3-1.81.31.9
Total locomotion distance, NPP test0.40.51.2-0.8-0.40.30.7-1.1-0.20.3-0.90.51.0
Locomotion velocity, NPP test0.81.12.1-1.3-1.0-0.31.1-1.4-0.8-0.2-1.41.01.4
Pavlov. Cond. lever latency1.72.25.1-1.1-1.7-2.31.1-0.4-1.9-1.8-1.01.60.7
Pavlov. Cond. magazine entry latency7.910.213.82.93.63.5-2.92.23.73.72.8-3.5-2.7
Pavlov. Cond. change in total contacts8.38.810.53.23.22.2-3.22.53.12.83.2-3.2-3.0
Pavlov. Cond. index score5.57.111.02.33.13.3-2.41.33.23.32.3-2.9-1.9
Pavlov. Cond. latency score4.05.19.01.82.63.0-1.91.02.82.81.8-2.5-1.5
Pavlov. Cond. lever contacts1.31.54.20.91.52.1-0.8-0.11.61.60.8-1.3-0.3
Pavlov. Cond. magazine entry number9.511.815.9-3.2-3.8-3.63.3-2.3-3.9-4.0-3.23.73.0
Pavlov. Cond. intertrial magazine entries0.91.12.0-0.8-1.2-1.40.8-0.6-1.4-1.4-0.71.10.6
Pavlov. Cond. lever-magazine prob. diff.6.37.911.52.63.33.3-2.61.53.33.42.5-3.0-2.0
Pavlov. Cond. response bias7.38.911.52.93.33.0-2.92.13.43.32.9-3.2-2.5
Bone: apparent density2.13.64.71.72.02.0-1.71.82.22.11.8-2.0-1.5
Bone surface0.10.10.4-0.3-0.00.60.40.20.30.3-0.2-0.10.5
Bone volume0.20.31.2-0.20.31.10.20.10.70.8-0.0-0.40.4
Bone: connectivity density3.25.06.22.12.42.2-2.22.22.52.42.2-2.3-1.9
Bone: cortical apparent density5.47.011.73.12.91.7-3.41.92.52.62.8-2.5-2.5
Bone: cortical area0.10.10.40.60.30.2-0.20.20.30.30.6-0.10.0
Bone: cortical porosity0.10.20.4-0.10.20.60.40.30.50.5-0.3-0.5-0.2
Bone: cortical porosity0.20.20.4-0.40.00.70.60.20.40.5-0.5-0.4-0.1
Bone: cortical thickness1.22.13.11.81.30.6-1.61.71.31.11.8-1.3-1.5
Bone: cortical thickness6.77.811.62.72.71.8-2.83.42.82.52.6-3.1-3.3
Bone: cortical tissue density5.36.911.63.12.81.7-3.41.92.52.62.8-2.5-2.5
Bone: elastic displacement0.10.10.70.20.0-0.1-0.1-0.8-0.3-0.10.20.40.5
Bone: elastic work0.10.20.30.40.40.6-0.20.40.50.50.5-0.4-0.3
Bone: endosteal estimation2.55.38.5-2.7-2.3-1.02.9-2.2-1.9-1.8-2.62.12.8
Bone: endosteal perimeter1.53.15.3-1.7-1.7-1.01.9-2.1-1.6-1.4-1.61.82.3
Bone: final force0.40.62.00.30.71.40.00.61.11.20.4-0.8-0.1
Bone: final moment0.30.41.70.10.51.30.20.30.91.00.2-0.60.1
Bone: marrow area2.35.08.0-2.6-2.3-0.92.8-2.2-1.9-1.8-2.62.02.7
Bone: maximum diameter0.00.10.20.30.20.40.1-0.10.30.30.2-0.20.2
Bone: maximum force0.10.20.7-0.4-0.30.30.8-0.10.00.0-0.30.20.7
Bone: maximum moment0.20.30.9-0.6-0.50.21.0-0.3-0.2-0.2-0.50.40.8
Bone: minimum diameter0.40.81.9-0.8-1.0-0.51.4-0.7-0.8-1.0-0.90.81.0
Bone: periosteal estimation0.40.71.8-0.9-0.8-0.01.3-0.8-0.5-0.5-0.90.71.2
Bone: periosteal perimeter0.91.52.9-1.2-1.1-0.41.6-1.4-1.0-0.8-1.31.31.7
Bone: post-yield work1.52.02.8-1.3-1.6-1.31.5-1.0-1.5-1.4-1.11.61.7
Bone: stiffness0.10.10.5-0.3-0.20.20.50.70.30.1-0.4-0.2-0.1
Bone: tissue strength1.61.53.1-0.9-1.0-1.01.0-1.4-1.3-1.1-0.71.61.8
Bone: trabecular number4.67.19.92.12.93.1-2.42.33.13.12.2-2.9-2.2
Bone: trabecular spacing2.12.84.4-2.0-1.6-0.62.0-1.9-1.5-1.2-2.11.51.6
Bone: trabecular thickness0.10.10.20.30.40.4-0.30.00.30.40.4-0.10.2
Bone: trabecular tissue density0.30.41.10.80.0-1.0-0.90.3-0.3-0.30.7-0.1-0.6
Breakpoint value in progressive ratio session0.20.20.50.60.50.4-0.40.50.5-0.20.7-0.5-0.2
Distance traveled before self-admin0.00.00.2-0.1-0.10.20.40.10.1-0.2-0.1-0.1-0.0
Distance traveled after self-admin1.21.33.4-1.2-1.2-0.91.4-0.4-1.1-1.9-1.10.90.7
Delta time in closed arm before/after self-admin2.82.73.7-1.7-1.9-1.41.8-1.0-1.9-1.7-1.71.81.3
Delta time in open arm before/after self-admin0.00.00.2-0.0-0.1-0.2-0.00.3-0.0-0.10.0-0.2-0.5
Diff in mean of infusions in LGA sessions0.10.20.40.70.30.2-0.20.10.3-0.60.6-0.3-0.2
Extinction: sum of active levers before priming1.61.62.4-1.2-1.3-0.81.5-0.9-1.3-1.2-1.21.41.5
Active lever presses in extinction session 62.32.24.21.21.22.1-0.21.51.91.61.2-1.9-1.0
Delta distance traveled before/after self-admin1.21.32.1-1.3-1.3-1.31.1-0.5-1.3-1.5-1.11.10.6
Delta ambulatory time before/after self-admin1.11.22.3-1.5-1.2-0.91.2-0.6-1.1-1.3-1.21.00.8
Time in closed arm before self-admin0.60.61.30.60.80.2-1.11.00.90.10.8-0.9-0.9
Time in closed arm after self-admin0.50.51.8-0.4-0.7-1.30.20.6-0.7-1.2-0.10.6-0.1
Time in open arm before self-admin0.80.91.5-0.6-1.1-0.81.2-0.8-1.1-0.8-0.71.01.0
Time in open arm after self-admin0.30.30.5-0.5-0.6-0.40.6-0.7-0.7-0.4-0.60.70.6
Sum of active levers in priming session hrs 5-60.80.82.40.60.60.7-0.41.60.90.80.8-1.2-1.0
Time to tail flick, vehicle, before self-admin0.50.52.7-0.2-0.10.00.1-1.6-0.40.2-0.70.91.1
Time to tail flick, vehicle, after self-admin0.10.10.5-0.20.10.40.3-0.70.10.2-0.40.10.5
Time to tail flick, test, before self-admin1.41.41.8-1.4-1.2-0.91.2-1.2-1.2-0.8-1.31.31.1
Time to tail flick, test, after self-admin0.40.42.3-0.2-0.00.60.2-1.5-0.10.1-0.70.30.9
Delta time to tail flick, vehicle, before/after SA0.30.31.2-0.00.41.10.20.00.60.7-0.0-0.60.1
Delta time to tail flick, test, before/after SA1.11.01.91.11.21.4-1.2-0.01.21.00.7-1.1-0.5
Ambulatory time before self-admin0.00.00.10.1-0.1-0.10.3-0.0-0.1-0.0-0.10.20.1
Ambulatory time after self-admin2.22.54.4-2.0-1.7-1.02.0-0.8-1.4-2.1-1.81.31.1
Total heroin consumption1.92.25.11.21.72.3-1.10.51.92.11.0-1.6-0.3
Area under the delay curve0.20.20.90.10.40.1-0.40.60.50.40.4-0.6-1.0
Delay disc. indifference point, 0s delay1.01.12.31.51.00.8-1.00.81.10.71.3-1.2-0.9
Delay disc. indifference point, 16s delay1.21.24.20.40.4-0.4-0.91.90.60.11.0-1.0-2.0
Delay disc. indifference point, 2s delay0.50.61.40.50.91.2-0.4-0.11.01.10.4-0.8-0.3
Delay disc. indifference point, 24s delay0.10.10.3-0.5-0.3-0.60.1-0.2-0.4-0.4-0.30.40.0
Delay disc. indifference point, 4s delay1.11.22.50.80.90.8-0.61.41.21.01.0-1.3-1.6
Delay disc. indifference point, 8s delay0.00.00.10.10.30.1-0.3-0.00.20.40.2-0.1-0.1
Delay discount exponential model param0.10.20.80.1-0.20.00.2-0.5-0.3-0.2-0.30.40.9
Delay discount hyperbolic model param0.20.20.9-0.2-0.3-0.10.3-0.5-0.5-0.3-0.40.50.9
Fecal boli incidents, locomotor time 11.01.13.2-1.1-0.8-0.40.8-1.8-0.9-0.7-1.31.01.1
Change in fecal boli incidents, locomotor task0.00.00.10.0-0.1-0.30.00.30.0-0.20.2-0.1-0.1
Time >=10cm from walls, locomotor time 10.30.31.31.10.4-0.2-0.70.40.20.00.9-0.2-0.4
Bouts of movement, locomotor time 10.10.10.5-0.4-0.5-0.20.7-0.0-0.4-0.3-0.20.30.2
Total resting periods, locomotor time 10.70.81.4-1.1-0.9-0.41.2-0.7-0.9-0.6-1.00.90.9
Rest time, locomotor task time 10.20.20.8-0.80.00.40.2-0.70.00.2-0.60.20.9
Distance moved, locomotor task time 10.30.31.20.70.10.1-0.30.80.30.00.5-0.5-1.1
Vertical activity count, locomotor time 10.10.10.2-0.3-0.4-0.30.30.1-0.3-0.4-0.30.40.0
Time >=10cm from walls, locomotor time 21.01.11.91.41.11.0-1.00.61.11.21.2-1.0-0.4
Bouts of movement, locomotor time 20.91.02.61.30.70.2-0.71.60.70.41.5-0.8-0.8
Total resting periods, locomotor time 20.80.92.61.30.6-0.0-0.71.60.50.21.4-0.8-0.8
Rest time, locomotor task time 20.80.91.3-1.1-0.9-0.71.0-0.9-0.9-0.8-1.00.91.1
Distance moved, locomotor task time 20.10.10.3-0.2-0.5-0.10.50.2-0.2-0.4-0.30.1-0.1
Vertical activity count, locomotor time 20.40.41.1-1.0-0.7-0.50.5-0.2-0.6-0.8-0.90.60.2
Weight adjusted by age0.10.10.4-0.1-0.40.30.70.1-0.0-0.4-0.2-0.10.2
Seeking ratio, delayed vs. immediate footshock0.80.92.21.50.6-0.6-1.20.90.30.41.3-0.5-1.4
Locomotion in novel chamber5.06.28.72.32.42.2-2.32.32.72.42.4-2.9-2.7
Locomotion in novel chamber post-restriction0.60.82.40.71.01.6-0.3-0.51.11.20.3-0.8-0.1
Progressive ratio0.10.10.6-0.10.40.8-0.10.10.50.20.1-0.5-0.0
Food seeking constrained by brief footshock0.20.30.8-0.10.60.9-0.20.60.70.50.1-0.8-0.3
Seeking ratio, punishment vs. effort0.00.00.1-0.0-0.2-0.30.00.1-0.20.0-0.10.1-0.1
Run reversals in cocaine runway, females1.31.33.9-0.5-1.4-2.00.90.6-1.4-1.5-0.41.2-0.2
Run reversals in cocaine runway, males0.40.40.80.50.50.5-0.60.40.60.70.4-0.6-0.9
Latency to leave start box in cocaine runway1.01.11.9-0.6-1.3-1.41.1-0.2-1.3-1.1-0.71.20.9
Latency to leave start box in cocaine runway, F0.80.91.7-0.6-1.3-1.11.20.3-1.1-1.1-0.71.00.5
Latency to leave start box in cocaine runway, M0.30.31.01.00.3-0.3-0.70.30.20.30.8-0.3-0.3
Cd content in liver0.20.20.60.20.20.1-0.10.60.40.60.5-0.6-0.8
Co content in liver0.30.40.8-0.5-0.7-0.90.3-0.5-0.9-0.8-0.40.60.0
Cu content in liver0.20.30.70.70.2-0.4-0.50.50.00.20.7-0.2-0.8
Fe content in liver0.70.81.7-1.2-1.1-0.61.3-0.3-0.8-1.0-0.90.80.6
K content in liver2.32.34.01.31.41.2-1.42.01.71.21.4-1.7-1.8
Mg content in liver2.82.95.51.91.40.3-2.02.31.30.91.9-1.5-2.3
Mn content in liver3.43.95.32.22.01.2-2.32.11.91.72.1-1.9-2.0
Na content in liver0.50.51.7-0.20.61.30.10.81.00.70.0-0.8-0.5
Rb content in liver1.31.62.51.51.40.9-1.51.01.21.21.6-1.2-1.2
Se content in liver6.68.010.12.72.92.1-3.02.82.92.72.8-3.1-3.2
Sr content in liver0.20.20.70.70.4-0.2-0.80.30.20.20.5-0.3-0.4
Zn content in liver2.83.14.41.72.01.7-1.91.11.92.11.4-2.0-1.7