Hub : Genes

Ppif

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000010558 0.13 0.07 3.1e-10 0.03 0.06 0.07 0.07 1.7e-04 1.2e-07 2.6e-08 3.5e-08
2 BLA gene expression ENSRNOG00000010558 0.33 0.11 0.0e+00 0.34 0.14 0.33 0.13 4.6e-19 7.4e-08 1.9e-18 1.4e-07
3 BLA mRNA stability ENSRNOG00000010558 0.14 0.08 1.6e-04 0.08 0.07 0.06 0.07 5.5e-05 1.2e-04 5.4e-04 1.0e-04
4 Brain alternative TSS ENSRNOT00000014382 0.14 0.08 1.4e-07 0.09 0.08 0.09 0.09 6.6e-09 1.5e-07 1.7e-08 1.3e-08
5 Brain alternative TSS ENSRNOT00000106999 0.15 0.09 4.7e-08 0.1 0.09 0.09 0.1 1.3e-09 2.0e-08 5.7e-09 2.0e-09
6 Brain gene expression ENSRNOG00000010558 0.47 0.19 0.0e+00 0.35 0.24 0.38 0.22 1.0e-33 8.8e-22 2.3e-37 1.2e-20
7 Brain mRNA stability ENSRNOG00000010558 0.16 0.08 4.8e-12 0.12 0.12 0.12 0.14 1.2e-11 4.2e-11 8.9e-11 1.3e-12
8 Eye gene expression ENSRNOG00000010558 0.4 0.19 9.0e-03 0.03 0 0.04 -0.01 1.1e-01 2.7e-01 8.6e-02 4.6e-01
9 IL gene expression ENSRNOG00000010558 0.51 0.17 4.0e-09 0.27 0.28 0.24 0.28 3.5e-07 1.6e-07 2.2e-06 2.3e-07
10 IL mRNA stability ENSRNOG00000010558 0.41 0.16 8.4e-07 0.05 0.24 0.19 0.16 2.9e-02 1.6e-06 2.4e-05 8.9e-05
11 LHb gene expression ENSRNOG00000010558 0.31 0.16 1.6e-05 0.13 0.16 0.12 0.16 4.8e-04 1.1e-04 7.0e-04 1.2e-04
12 LHb mRNA stability ENSRNOG00000010558 0.34 0.16 6.3e-05 0.17 0.22 0.27 0.25 6.6e-05 5.5e-06 3.4e-07 1.2e-06
13 Liver alternative TSS ENSRNOT00000014382 0.19 0.09 0.0e+00 0.16 0.16 0.17 0.17 5.0e-17 6.9e-18 3.9e-18 2.7e-18
14 Liver alternative TSS ENSRNOT00000106999 0.19 0.09 0.0e+00 0.16 0.16 0.16 0.17 6.4e-17 1.3e-17 6.3e-18 4.1e-18
15 Liver gene expression ENSRNOG00000010558 0.71 0.08 0.0e+00 0.61 0.61 0.61 0.62 1.1e-84 7.8e-86 5.0e-86 1.4e-87
16 Liver isoform ratio ENSRNOT00000014382 0.04 0.03 1.4e-04 0.02 0.02 0.02 0.02 5.3e-03 9.3e-04 5.3e-03 3.2e-03
17 Liver isoform ratio ENSRNOT00000106999 0.04 0.03 1.1e-04 0.02 0.03 0.02 0.02 3.1e-03 5.3e-04 1.1e-03 1.9e-03
18 NAcc gene expression ENSRNOG00000010558 0.18 0.1 2.4e-11 0.16 0.14 0.15 0.15 2.4e-12 9.3e-11 2.0e-11 2.9e-11
19 NAcc mRNA stability ENSRNOG00000010558 0.11 0.07 7.6e-05 0.04 0.06 0.04 0.04 4.6e-04 3.7e-05 9.1e-04 6.1e-04
20 OFC gene expression ENSRNOG00000010558 0.36 0.17 1.9e-05 0.17 0.11 0.17 0.18 7.3e-05 1.2e-03 8.5e-05 4.2e-05
21 OFC mRNA stability ENSRNOG00000010558 0.5 0.19 7.3e-07 0.11 0.21 0.2 0.2 1.3e-03 9.0e-06 1.8e-05 1.8e-05
22 PL gene expression ENSRNOG00000010558 0.38 0.13 0.0e+00 0.31 0.34 0.34 0.34 3.0e-24 7.8e-27 2.2e-26 1.5e-26
23 PL mRNA stability ENSRNOG00000010558 0.29 0.11 9.4e-16 0.17 0.22 0.22 0.22 2.5e-13 3.0e-16 9.7e-17 1.9e-16

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
BMI with tail1.75.410.91.0-1.7-2.02.0-2.0-2.3-3.2-2.2-3.1-2.9-3.0-1.4-1.41.42.9-2.02.1-1.9-2.3-1.8-2.9-2.6-3.3
BMI without tail1.53.25.6-0.2-1.8-0.40.7-0.7-2.2-2.3-1.9-2.2-1.5-2.1-0.2-2.02.02.4-2.02.1-1.9-0.8-1.9-1.6-2.4-2.2
Body weight1.66.712.80.5-2.2-2.01.9-1.9-2.7-3.6-2.5-3.4-3.0-3.4-1.6-1.91.93.4-2.52.5-2.1-2.3-2.1-3.1-3.0-3.5
Epididymis fat weight0.81.84.2-2.1-1.61.7-1.71.7-1.4-0.2-1.4-0.10.9-0.21.6-1.81.80.5-1.51.4-1.51.6-1.40.9-1.10.2
Glucose0.10.20.30.30.5-0.20.3-0.30.40.10.40.2-0.20.1-0.60.5-0.5-0.30.5-0.50.5-0.40.5-0.10.50.2
Heart weight0.00.00.20.20.1-0.50.1-0.1-0.10.1-0.1-0.1-0.2-0.1-0.30.4-0.40.00.1-0.10.1-0.20.0-0.2-0.0-0.1
Left kidney weight0.30.91.8-1.4-1.00.7-0.70.7-1.2-0.9-1.0-0.6-0.1-0.80.5-1.31.30.8-1.21.2-1.20.3-1.2-0.1-1.0-0.4
Right kidney weight0.51.53.20.9-0.3-1.61.5-1.5-0.9-1.6-0.7-1.6-1.8-1.6-1.5-0.20.21.4-0.60.7-0.3-1.7-0.3-1.8-1.0-1.6
Tail length0.00.10.4-0.2-0.30.30.1-0.1-0.5-0.4-0.2-0.4-0.2-0.4-0.1-0.60.60.5-0.40.4-0.30.0-0.4-0.2-0.6-0.3
Length with tail0.10.31.10.60.1-0.70.8-0.8-0.1-0.60.1-0.5-0.7-0.5-1.00.1-0.10.50.0-0.00.3-0.70.2-0.7-0.3-0.5
Length without tail0.71.54.11.40.2-2.01.7-1.7-0.2-1.3-0.2-1.2-1.7-1.2-1.90.6-0.60.90.00.00.4-1.90.3-1.7-0.4-1.4
Liver weight, left0.91.42.81.1-0.5-1.41.5-1.5-0.9-1.4-0.9-1.6-1.6-1.4-1.2-0.30.31.5-0.60.7-0.6-1.4-0.6-1.7-1.2-1.6
Liver weight, right0.61.02.51.30.0-1.61.5-1.5-0.3-1.2-0.3-1.1-1.4-1.0-1.20.2-0.21.0-0.20.2-0.1-1.4-0.1-1.5-0.6-1.3
Parametrial fat weight1.12.24.3-1.5-1.80.8-0.70.7-1.9-1.4-1.9-1.2-0.4-1.40.8-2.12.11.5-2.02.0-1.90.3-1.9-0.4-1.7-1.0
Retroperitoneal fat weight1.03.46.6-1.7-2.20.5-0.50.5-2.4-1.9-2.4-1.8-0.8-2.00.6-2.62.62.1-2.42.4-2.3-0.0-2.3-0.8-2.2-1.5
Intraocular pressure0.50.71.50.70.9-0.40.4-0.41.10.60.90.70.10.7-0.61.0-1.0-0.81.1-1.11.2-0.31.10.21.10.6
Extensor digitorum longus weight0.62.67.52.01.3-2.42.4-2.40.8-0.70.8-0.8-2.0-0.7-2.71.5-1.50.41.2-1.11.3-2.51.3-1.90.6-0.9
Soleus weight2.57.212.3-1.0-3.1-0.70.6-0.6-3.3-3.2-3.4-3.2-2.2-3.3-0.1-2.92.93.5-3.23.2-3.1-1.2-3.0-2.3-3.4-2.9
Tibialis anterior weight1.44.710.31.8-0.5-2.82.8-2.8-1.3-2.8-1.1-2.7-3.2-2.6-2.6-0.20.22.5-0.91.0-0.6-3.0-0.6-3.2-1.6-2.8
Tibia length0.82.14.8-1.10.31.8-1.91.90.91.90.71.92.21.81.80.2-0.2-1.80.6-0.60.42.00.42.21.11.8
Number of licking bursts0.10.10.20.3-0.40.0-0.10.1-0.4-0.1-0.4-0.2-0.0-0.20.2-0.30.30.3-0.40.4-0.30.1-0.3-0.0-0.4-0.2
Food consumed during 24 hour testing period2.73.28.52.91.9-2.62.4-2.41.4-0.01.6-0.1-1.40.1-2.42.2-2.2-0.41.8-1.72.0-2.12.0-1.41.1-0.6
Times rat made contact with spout4.55.216.64.12.3-3.23.2-3.21.6-0.41.7-0.5-2.0-0.2-3.22.6-2.6-0.22.1-1.92.4-2.82.4-2.01.1-1.1
Mean time between licks in bursts1.52.03.50.21.50.8-0.70.71.71.81.71.81.51.90.51.2-1.2-1.91.5-1.61.51.01.51.51.71.7
Mean num. licks in bursts1.41.63.51.71.4-1.71.7-1.71.1-0.21.1-0.1-1.1-0.0-1.91.5-1.5-0.21.3-1.31.4-1.61.4-1.00.9-0.4
Std. dev. time between licks in bursts1.41.64.5-1.3-0.32.0-1.91.90.11.30.21.22.01.32.0-0.60.6-1.0-0.20.1-0.22.1-0.21.90.21.3
Water consumed over 24 hours0.50.52.41.50.6-1.21.0-1.00.3-0.20.4-0.3-0.7-0.2-1.00.8-0.80.10.5-0.40.6-0.90.6-0.70.1-0.5
Indifference point 0 sec1.62.57.12.71.7-2.02.2-2.21.20.11.5-0.1-1.20.1-2.21.9-1.9-0.51.7-1.61.8-1.81.8-1.21.0-0.4
Indifference point AUC0.60.72.9-1.7-1.10.9-0.90.9-0.8-0.2-1.0-0.20.4-0.30.9-1.01.00.4-0.90.9-1.10.7-1.10.4-0.60.2
Indifference point function ln k0.81.13.71.90.9-1.51.5-1.50.5-0.50.7-0.5-1.1-0.4-1.51.0-1.00.20.7-0.60.9-1.40.9-1.10.2-0.8
Indifference point function log k0.81.13.71.90.9-1.51.5-1.50.5-0.50.7-0.5-1.1-0.4-1.51.0-1.00.20.7-0.60.9-1.40.9-1.10.2-0.8
Delay discounting total patch changes 0 sec1.52.46.32.51.6-2.12.1-2.11.1-0.11.3-0.2-1.3-0.0-2.21.7-1.7-0.31.5-1.41.7-1.91.7-1.30.9-0.5
Delay discounting total patch changes 12 sec0.91.22.91.21.0-1.51.5-1.50.9-0.10.8-0.1-1.0-0.1-1.71.2-1.2-0.21.2-1.11.1-1.51.1-0.91.0-0.2
Delay discounting total patch changes 18 sec0.81.02.21.11.1-1.01.0-1.01.10.61.00.4-0.30.5-1.11.5-1.5-0.81.3-1.31.2-0.81.2-0.31.20.4
Delay discounting total patch changes 24 sec0.00.10.1-0.4-0.30.2-0.30.3-0.20.3-0.30.10.20.00.2-0.30.20.0-0.10.1-0.20.3-0.30.2-0.10.3
Delay discounting total patch changes 6 sec0.20.30.60.3-0.3-0.60.7-0.7-0.5-0.7-0.3-0.7-0.8-0.7-0.7-0.40.40.8-0.30.30.0-0.7-0.0-0.8-0.5-0.7
Delay discounting time to switch 0 sec0.81.32.5-0.30.81.1-1.01.01.11.61.01.51.51.51.10.6-0.6-1.50.8-0.80.71.30.71.51.11.3
Delay discounting water rate 0 sec1.62.64.60.3-1.6-0.91.0-1.0-1.9-2.1-1.8-2.1-1.7-2.1-0.7-1.31.42.2-1.71.7-1.6-1.2-1.6-1.7-2.0-2.0
Delay discounting water rate 12 sec0.71.12.11.0-0.5-1.11.2-1.2-0.8-1.3-0.7-1.3-1.4-1.3-1.1-0.30.31.2-0.60.7-0.5-1.3-0.5-1.4-1.0-1.5
Delay discounting water rate 18 sec0.30.41.00.1-0.5-0.10.2-0.2-0.8-1.0-0.5-0.8-0.5-0.7-0.0-0.80.81.0-0.80.8-0.5-0.2-0.6-0.6-1.0-0.9
Delay discounting water rate 24 sec3.04.17.30.3-2.0-0.91.1-1.1-2.4-2.6-2.2-2.6-2.0-2.6-0.7-2.02.02.7-2.22.2-1.9-1.3-2.0-2.1-2.6-2.6
Delay discounting water rate 6 sec0.50.71.50.3-0.6-0.40.4-0.4-1.0-1.1-0.7-1.1-0.8-1.0-0.2-0.80.81.2-0.90.9-0.8-0.4-0.8-0.8-1.2-1.1
Locomotor activity0.81.33.21.50.0-1.21.5-1.5-0.6-1.5-0.3-1.4-1.5-1.2-1.1-0.30.31.3-0.50.6-0.2-1.5-0.2-1.6-1.0-1.8
Locomotor testing distance1.62.75.20.2-1.6-0.30.5-0.5-2.0-2.1-1.8-2.0-1.2-1.90.1-1.81.82.2-2.02.1-1.8-0.6-1.8-1.4-2.3-2.1
Locomotor testing rearing1.21.94.71.0-0.9-0.81.2-1.2-1.5-1.8-1.2-1.9-1.5-1.7-0.7-1.01.01.8-1.31.4-1.1-1.1-1.0-1.7-1.8-2.2
Light reinforcement 10.10.20.40.30.6-0.20.1-0.10.50.40.50.40.20.5-0.10.6-0.6-0.40.5-0.50.50.10.50.20.40.2
Light reinforcement 20.71.01.70.21.10.4-0.40.41.31.11.21.30.91.30.20.9-0.9-1.31.1-1.11.10.51.10.91.31.0
Reaction time number correct0.20.31.41.20.6-0.60.7-0.70.50.10.5-0.0-0.30.1-0.40.7-0.7-0.10.5-0.50.4-0.50.4-0.30.2-0.2
Reaction time mean minus median1.62.14.7-1.3-1.91.0-0.80.8-1.8-1.1-1.7-1.1-0.1-1.11.0-2.22.21.4-2.01.9-1.80.6-1.8-0.2-1.8-1.0
Reaction time mean minus median AUC2.12.75.0-1.1-2.10.3-0.30.3-2.2-1.7-2.0-1.6-0.8-1.70.4-2.22.21.9-2.22.2-2.0-0.0-2.0-0.8-2.1-1.5
Reaction time num false alarms1.01.32.51.61.5-1.00.8-0.81.40.81.40.7-0.00.8-0.91.6-1.6-1.01.5-1.51.4-0.61.4-0.01.30.6
Reaction time num false alarms AUC0.60.81.41.01.1-0.30.2-0.21.20.91.20.90.51.0-0.21.1-1.1-1.01.2-1.21.00.01.10.51.10.9
Reaction time trials correct on left0.20.31.41.20.6-0.60.7-0.70.50.10.5-0.0-0.30.1-0.40.7-0.7-0.10.5-0.50.4-0.50.4-0.30.2-0.2
Reaction time trials on left0.10.21.11.10.4-0.50.6-0.60.40.00.4-0.1-0.20.1-0.30.5-0.5-0.00.3-0.30.3-0.40.2-0.30.1-0.2
Reaction time mean1.11.53.2-1.2-1.50.6-0.60.6-1.6-1.2-1.3-1.0-0.3-1.10.6-1.81.81.3-1.71.7-1.50.2-1.5-0.4-1.5-1.0
Reaction time mean AUC0.81.12.4-1.3-1.30.9-0.90.9-1.3-0.8-1.0-0.60.1-0.70.9-1.61.60.8-1.41.4-1.30.6-1.20.1-1.2-0.5
Median of all reaction times0.50.71.5-1.0-0.90.5-0.50.5-1.0-0.8-0.8-0.7-0.2-0.80.5-1.21.20.8-1.11.1-1.10.2-1.0-0.2-1.0-0.6
Reaction time omissions1.01.32.6-1.6-1.31.3-1.11.1-1.1-0.6-1.0-0.40.6-0.31.6-1.51.50.6-1.51.4-1.51.1-1.50.5-1.2-0.4
Reaction time false alarm rate0.20.20.60.00.30.2-0.40.40.50.60.50.60.50.60.30.3-0.3-0.60.5-0.50.30.40.40.60.60.8
Reaction time premature initiation rate2.43.26.7-2.0-2.41.5-1.51.5-2.1-0.9-2.1-0.90.5-0.92.0-2.32.31.3-2.32.3-2.41.4-2.60.3-2.0-0.5
Reaction time premature initiations1.72.45.7-1.2-2.11.0-0.90.9-1.9-1.0-1.9-1.10.2-1.01.6-2.02.01.4-2.12.1-2.10.9-2.40.0-2.0-0.8
Std. dev. reaction times2.23.16.5-1.6-2.21.0-0.80.8-2.3-1.5-2.0-1.4-0.3-1.51.0-2.52.51.8-2.42.4-2.20.5-2.1-0.4-2.2-1.3
Reaction time trials completed0.10.21.11.10.4-0.50.6-0.60.40.00.4-0.1-0.20.1-0.30.5-0.5-0.00.3-0.30.3-0.40.2-0.30.1-0.2
Reaction time trials AUC0.20.31.31.10.2-0.80.8-0.80.0-0.40.0-0.5-0.6-0.3-0.50.3-0.30.40.1-0.00.0-0.7-0.0-0.6-0.3-0.6
Social response proportion0.10.20.40.00.60.3-0.20.20.50.30.70.40.30.50.20.4-0.4-0.50.3-0.30.60.20.50.30.30.2
Social responses0.91.22.20.51.30.8-0.60.61.31.31.51.41.21.50.70.8-0.8-1.31.1-1.11.20.91.21.21.11.2
Social time0.40.52.2-0.50.01.2-1.11.10.00.40.20.51.10.61.5-0.50.5-0.3-0.40.3-0.31.2-0.31.0-0.20.4
Conditioned locomotion2.63.05.4-0.8-1.9-0.60.5-0.5-2.2-2.2-2.1-2.1-1.6-2.3-0.3-1.81.82.3-2.02.0-2.0-0.9-2.0-1.6-2.1-1.8
Cocaine response after cond. corrected0.30.30.9-0.9-0.50.8-0.90.9-0.30.2-0.40.20.60.10.9-0.60.5-0.1-0.50.4-0.60.8-0.60.6-0.10.4
Cocaine response after cond. not corrected0.30.30.8-0.8-0.20.8-0.90.9-0.00.5-0.10.50.70.40.7-0.30.3-0.4-0.10.1-0.20.8-0.20.80.20.7
Cocaine response before conditioning0.70.81.60.91.2-0.60.7-0.71.00.61.10.5-0.10.6-1.01.2-1.2-0.71.2-1.21.3-0.61.3-0.11.00.4
Saline control response1.92.55.32.2-0.2-2.32.3-2.3-0.7-1.8-0.5-1.9-2.2-1.7-1.90.3-0.31.5-0.40.5-0.2-2.2-0.2-2.3-1.1-2.1
Condit. Reinf. active minus inactive responses0.20.20.4-0.5-0.60.2-0.20.2-0.6-0.3-0.5-0.3-0.1-0.40.3-0.60.60.4-0.60.6-0.60.1-0.6-0.1-0.5-0.2
Condit. Reinf. active-inactive response ratio1.31.42.7-1.2-1.60.6-0.60.6-1.5-0.8-1.5-0.9-0.2-1.10.7-1.61.61.2-1.51.5-1.60.3-1.6-0.2-1.3-0.6
Condit. Reinf. active responses0.10.10.2-0.0-0.2-0.30.2-0.2-0.3-0.4-0.2-0.4-0.4-0.4-0.1-0.20.20.4-0.30.3-0.3-0.3-0.3-0.4-0.3-0.4
Condit. Reinf. inactive responses1.41.73.21.61.8-0.70.7-0.71.71.01.71.00.21.1-0.71.8-1.8-1.31.7-1.71.7-0.41.70.21.50.7
Condit. Reinf. lever presses0.71.02.51.30.5-1.51.5-1.50.1-0.90.2-0.9-1.4-0.8-1.50.5-0.50.60.3-0.20.4-1.60.4-1.4-0.1-0.9
Condit. Reinf. lever reinforcers received0.20.20.40.1-0.4-0.30.3-0.3-0.5-0.6-0.4-0.6-0.5-0.6-0.1-0.30.30.6-0.50.5-0.5-0.4-0.5-0.5-0.6-0.6
Pavlov. Cond. lever latency1.72.45.1-2.3-1.91.8-1.81.8-1.5-0.3-1.6-0.30.9-0.42.0-2.02.00.7-1.81.7-1.81.6-1.80.8-1.30.0
Pavlov. Cond. magazine entry latency1.41.62.90.81.7-0.40.3-0.31.71.21.71.20.41.2-0.71.6-1.6-1.31.7-1.71.7-0.21.70.51.61.0
Pavlov. Cond. change in total contacts1.31.74.02.01.4-1.81.8-1.81.0-0.11.1-0.2-1.2-0.1-2.01.6-1.5-0.21.3-1.21.4-1.71.4-1.10.9-0.4
Pavlov. Cond. index score1.52.03.61.71.9-1.21.1-1.11.70.81.70.7-0.30.8-1.41.9-1.9-1.01.8-1.81.9-1.01.9-0.21.50.5
Pavlov. Cond. latency score1.72.24.01.92.0-1.41.3-1.31.70.71.80.6-0.50.7-1.62.0-2.0-1.01.9-1.82.0-1.12.0-0.41.50.4
Pavlov. Cond. lever contacts1.11.63.51.91.5-1.61.6-1.61.20.01.20.0-0.90.1-1.71.6-1.6-0.41.3-1.31.4-1.51.4-0.91.0-0.2
Pavlov. Cond. magazine entry number0.91.22.3-1.1-1.50.8-0.70.7-1.4-0.6-1.4-0.70.1-0.71.0-1.41.40.9-1.41.4-1.50.7-1.50.0-1.3-0.5
Pavlov. Cond. intertrial magazine entries1.72.34.2-1.0-2.00.4-0.40.4-2.0-1.4-2.0-1.4-0.5-1.50.8-1.91.91.6-2.02.0-2.10.2-2.1-0.6-2.0-1.2
Pavlov. Cond. lever-magazine prob. diff.1.51.93.51.61.9-1.01.0-1.01.70.91.80.9-0.10.9-1.21.9-1.9-1.11.8-1.81.9-0.81.9-0.11.60.6
Pavlov. Cond. response bias1.21.73.11.71.7-1.31.2-1.21.50.51.50.5-0.50.6-1.41.7-1.7-0.81.6-1.61.7-1.11.7-0.41.30.3
Conditioned reinforcement - actives0.50.51.00.2-0.4-1.00.7-0.7-0.7-0.9-0.6-1.0-1.0-1.0-0.7-0.40.41.0-0.50.5-0.5-0.8-0.5-1.0-0.6-0.8
Conditioned reinforcement - inactives2.12.44.70.5-1.1-1.51.5-1.5-1.5-2.2-1.5-2.0-2.0-2.0-1.3-1.01.02.1-1.11.2-1.0-1.6-1.0-2.0-1.5-1.9
Conditioned locomotion0.60.72.11.10.3-1.51.4-1.4-0.0-0.7-0.0-0.7-1.1-0.6-1.20.4-0.40.70.3-0.30.2-1.20.2-1.1-0.1-0.6
Intermittent access intake day 1-15 change0.10.10.30.2-0.20.5-0.10.1-0.10.2-0.30.00.30.10.4-0.00.0-0.2-0.20.2-0.20.4-0.20.2-0.3-0.1
Intermittent access intake escalation0.40.41.1-0.5-0.51.0-0.80.8-0.20.5-0.50.40.80.41.1-0.30.2-0.4-0.40.3-0.41.0-0.40.8-0.20.3
Intermittent access intake escalation 20.30.30.70.1-0.70.00.3-0.3-0.7-0.6-0.8-0.7-0.4-0.60.0-0.40.40.5-0.70.7-0.6-0.1-0.6-0.5-0.8-0.8
Intermitt. access day 1 inactive lever presses0.10.10.40.5-0.1-0.40.5-0.5-0.2-0.6-0.2-0.5-0.5-0.4-0.5-0.00.00.4-0.10.1-0.0-0.4-0.0-0.5-0.3-0.4
Intermitt. access day 15 inactive lever presses0.10.10.2-0.4-0.40.3-0.10.1-0.4-0.1-0.5-0.20.1-0.10.2-0.50.50.2-0.30.3-0.30.3-0.30.1-0.4-0.1
Intermitt. access escalation Index2.11.94.3-1.5-1.71.2-0.80.8-1.5-1.2-1.5-0.90.0-0.91.3-2.12.11.2-1.81.8-1.80.6-1.8-0.0-1.6-0.9
Intermittent access day 1 total infusions2.52.88.82.51.0-3.02.6-2.60.4-1.10.5-1.1-2.2-1.0-2.71.2-1.10.90.9-0.81.1-2.51.1-2.10.2-1.2
Intermittent access day 15 total infusions1.11.23.82.01.2-1.51.5-1.50.9-0.00.8-0.0-0.80.1-1.41.3-1.3-0.31.1-1.11.2-1.21.2-0.80.7-0.2
Intermittent access terminal intake (last 3 days)1.82.06.12.51.0-2.12.2-2.20.6-0.70.5-0.7-1.6-0.5-2.21.3-1.20.31.0-0.91.2-1.91.2-1.60.4-0.8
Intermittent access total infusions1.11.23.51.60.9-1.91.7-1.70.5-0.60.5-0.5-1.2-0.4-1.80.9-0.90.30.9-0.81.0-1.51.0-1.20.4-0.5
Intermittent access day 1 locomotion2.32.35.72.21.6-2.42.0-2.01.1-0.31.1-0.2-1.4-0.1-2.31.8-1.8-0.01.5-1.41.6-1.91.6-1.31.0-0.3
Intermittent access day 15 total locomotion1.01.12.81.60.7-1.71.6-1.60.3-0.70.4-0.6-1.3-0.6-1.60.7-0.70.50.6-0.60.6-1.60.6-1.30.3-0.6
Intermittent access total locomotion1.61.84.82.11.0-2.22.1-2.10.6-0.60.6-0.7-1.6-0.5-2.01.2-1.10.41.0-0.91.0-1.91.0-1.50.4-0.7
Intermittent access standard deviation1.21.22.40.1-1.3-0.20.5-0.5-1.5-1.4-1.5-1.4-0.9-1.3-0.3-1.11.11.4-1.31.3-1.1-0.4-1.1-1.0-1.5-1.3
Cocaine induced anxiety0.10.20.3-0.6-0.50.3-0.30.3-0.5-0.3-0.5-0.3-0.1-0.40.2-0.40.40.3-0.60.6-0.50.0-0.5-0.1-0.4-0.3
Post-drug Anxiety0.50.51.41.20.7-0.81.1-1.10.40.00.5-0.2-0.7-0.2-1.20.9-0.9-0.00.6-0.60.7-0.90.7-0.70.3-0.3
Baseline Anxiety0.90.91.91.31.2-1.11.3-1.30.8-0.01.0-0.1-0.80.1-1.41.0-1.0-0.11.0-0.91.2-1.21.2-0.70.7-0.2
Lifetime Intake1.61.85.31.91.1-2.32.0-2.00.7-0.60.6-0.5-1.5-0.4-2.21.2-1.20.31.1-1.01.3-1.91.3-1.40.6-0.5
Incentive Sensitization - Responses2.62.67.22.72.1-1.82.1-2.11.5-0.01.80.2-0.90.4-2.11.8-1.8-0.51.9-1.82.0-1.62.0-1.01.2-0.2
Incentive Sensitization - Breakpoint2.52.56.92.62.1-1.62.0-2.01.5-0.01.80.2-0.90.5-2.01.7-1.7-0.61.8-1.82.0-1.52.0-0.91.2-0.1
Progressive ratio test 1 active lever presses2.22.27.41.70.4-2.72.2-2.20.0-1.4-0.1-1.3-2.2-1.3-2.40.8-0.71.10.5-0.40.6-2.40.6-2.1-0.0-1.2
Progressive ratio test 1 breakpoint2.82.98.92.10.7-3.02.6-2.60.2-1.40.2-1.3-2.4-1.3-2.81.0-1.01.00.7-0.60.9-2.70.9-2.30.1-1.2
Progressive ratio test 1 inactive lever presses1.31.34.21.40.3-2.01.8-1.80.0-1.1-0.1-1.0-1.6-0.9-1.80.8-0.80.80.4-0.30.5-1.80.5-1.6-0.1-1.0
Progressive ratio test 2 active lever presses2.82.97.12.71.7-2.62.5-2.51.2-0.51.3-0.3-1.6-0.2-2.51.8-1.80.01.6-1.61.8-2.21.8-1.61.0-0.5
Progressive ratio test 2 breakpoint2.22.56.32.31.4-2.52.3-2.30.9-0.61.0-0.5-1.6-0.4-2.41.5-1.50.21.4-1.31.5-2.11.5-1.60.8-0.5
Progressive ratio test 2 inactive lever presses0.50.61.10.3-0.6-0.90.8-0.8-0.7-1.1-0.9-1.0-1.0-1.0-0.6-0.30.31.0-0.50.5-0.6-0.8-0.6-1.0-0.7-0.8
Total sessions with >9 infusions2.42.77.82.31.2-2.82.5-2.50.6-0.90.6-0.9-2.0-0.8-2.71.3-1.30.61.1-1.01.3-2.41.3-1.90.5-0.9
Short access day 1 total inactive lever presses0.80.91.80.3-1.0-0.80.7-0.7-1.1-1.2-1.4-1.2-0.9-1.2-0.4-0.60.61.3-0.90.9-0.9-0.6-0.9-1.0-1.2-1.1
Short access day 10 total inactive lever presses1.11.22.0-0.11.10.6-0.60.61.31.11.11.41.01.40.31.1-1.1-1.31.1-1.21.30.71.31.11.31.3
Short access day 1 total infusions1.81.95.81.50.3-2.42.0-2.0-0.2-1.5-0.4-1.4-2.0-1.3-2.20.5-0.51.10.2-0.10.4-2.10.4-2.0-0.3-1.3
Short access day 10 total infusions0.50.61.11.00.9-1.00.8-0.80.80.30.70.2-0.30.3-0.90.9-0.9-0.21.0-1.01.0-0.61.0-0.30.70.3
Short access total infusions2.12.47.12.31.2-2.72.3-2.30.7-0.60.7-0.6-1.7-0.5-2.51.5-1.50.41.3-1.21.4-2.11.4-1.60.6-0.6
Short access day 1 locomotion2.02.17.51.60.4-2.72.1-2.10.0-1.4-0.2-1.2-2.1-1.2-2.31.0-1.01.00.4-0.30.7-2.20.7-2.0-0.0-1.2
Short access day 10 total locomotion0.10.10.40.40.6-0.30.3-0.30.40.00.60.2-0.00.3-0.30.5-0.5-0.10.5-0.50.5-0.20.5-0.00.40.3
Short access total locomotion0.70.71.50.91.2-0.90.7-0.71.00.31.00.4-0.20.5-0.91.1-1.0-0.41.2-1.11.2-0.51.2-0.11.00.5
Compulsive drug intake1.51.53.4-1.10.11.7-1.81.80.61.20.61.41.81.31.70.1-0.2-1.40.2-0.20.01.70.01.80.71.4
One hour access (0.3 mA shock)1.21.42.81.71.5-1.21.1-1.11.30.51.40.5-0.40.6-1.31.6-1.6-0.71.5-1.41.5-0.91.5-0.31.20.3
One hour access (shock baseline)0.70.82.31.40.5-1.51.4-1.40.3-0.50.3-0.5-1.1-0.5-1.50.7-0.70.40.6-0.50.7-1.30.7-1.10.2-0.6
Number of responses in last shaping day0.90.92.60.71.0-0.80.2-0.21.10.60.70.80.20.8-0.61.6-1.6-0.81.2-1.21.3-0.21.30.31.20.7
Context. condit. distance diff. score0.10.10.5-0.7-0.2-0.20.1-0.1-0.3-0.4-0.3-0.3-0.5-0.5-0.5-0.20.20.4-0.10.1-0.0-0.4-0.0-0.40.0-0.1
Locomotion velocity, session 14.34.78.21.72.9-0.60.5-0.52.82.12.82.10.92.2-0.92.8-2.8-2.52.8-2.82.8-0.12.80.92.61.7
Locomotion distance, session 15.06.512.32.53.4-1.41.4-1.43.22.13.22.00.32.1-1.83.5-3.5-2.53.4-3.43.4-0.93.40.43.11.4
Locomotion velocity, session 22.73.16.50.92.3-0.50.4-0.42.41.72.21.70.51.6-0.92.3-2.3-2.02.4-2.42.2-0.32.10.72.51.6
Locomotion distance, session 22.43.56.71.72.5-1.21.2-1.22.41.42.31.30.01.4-1.52.6-2.6-1.82.5-2.52.4-0.92.40.12.31.0
Locomotion velocity, session 33.23.87.02.12.6-1.01.0-1.02.51.62.51.50.31.7-1.22.6-2.6-1.92.6-2.52.6-0.62.70.42.31.1
Locomotion distance, session 32.62.86.42.51.8-2.32.3-2.31.4-0.11.5-0.1-1.40.0-2.42.0-2.0-0.31.7-1.61.9-2.11.9-1.31.1-0.5
Stereotopy head waving bouts, day 30.30.41.10.1-0.80.10.0-0.0-0.8-0.6-0.7-0.7-0.2-0.60.3-0.70.70.7-0.80.8-0.70.1-0.7-0.3-1.0-0.8
Stereotopy head waving duration, day 30.91.12.1-0.8-1.40.9-0.80.8-1.3-0.6-1.2-0.60.3-0.61.2-1.41.40.8-1.51.4-1.40.8-1.40.2-1.5-0.6
Locomotion velocity, session 74.55.09.72.43.0-1.61.5-1.52.71.62.91.5-0.11.6-1.93.1-3.1-2.03.0-2.92.9-1.12.90.02.61.1
Locomotion distance, session 72.63.36.42.32.2-1.81.8-1.82.00.81.90.7-0.80.7-2.22.5-2.5-1.12.3-2.22.2-1.62.2-0.61.90.4
Stereotopy head waving bouts, day 72.02.35.0-2.2-1.91.2-1.21.2-1.8-1.0-1.7-0.90.2-1.01.4-2.12.11.2-2.01.9-1.90.9-1.90.1-1.7-0.5
Stereotopy head waving duration, day 71.82.26.7-2.6-1.81.5-1.51.5-1.6-0.6-1.5-0.50.5-0.71.6-2.02.00.9-1.81.7-1.71.2-1.70.5-1.3-0.2
Locomotion velocity, session 85.56.512.00.83.00.1-0.20.23.33.03.02.91.72.9-0.33.1-3.1-3.23.2-3.33.00.63.01.83.52.7
Locomotion distance, session 81.92.95.41.52.3-1.21.2-1.22.11.12.11.1-0.21.1-1.72.3-2.3-1.42.3-2.32.3-1.02.3-0.12.10.8
Degree of sensitization distance0.00.00.1-0.20.10.1-0.10.10.10.3-0.00.20.00.0-0.10.2-0.2-0.20.2-0.2-0.0-0.0-0.00.10.30.3
Degree of sensitization stereotypy1.61.86.1-2.5-1.41.7-1.71.7-1.2-0.3-1.1-0.10.9-0.21.7-1.81.80.5-1.41.4-1.41.4-1.40.8-1.00.2
Condit. Reinf. active minus inactive responses0.30.30.80.70.1-0.90.8-0.8-0.0-0.6-0.1-0.5-0.8-0.5-0.80.1-0.10.50.1-0.00.0-0.90.0-0.8-0.1-0.6
Condit. Reinf. active-inactive response ratio1.61.72.9-0.6-1.6-0.10.1-0.1-1.6-1.5-1.7-1.5-0.8-1.40.2-1.61.61.7-1.61.7-1.6-0.3-1.6-0.9-1.7-1.3
Condit. Reinf. active responses0.40.51.31.10.8-0.90.8-0.80.80.20.70.2-0.30.3-0.81.0-1.0-0.40.9-0.80.7-0.60.7-0.30.60.1
Condit. Reinf. inactive responses2.63.16.01.72.2-0.70.6-0.62.21.72.21.60.61.7-0.92.4-2.5-2.02.3-2.32.1-0.22.20.62.11.3
Incentive salience index mean0.10.10.30.5-0.1-0.50.5-0.5-0.2-0.5-0.2-0.5-0.4-0.4-0.3-0.20.20.5-0.20.2-0.2-0.4-0.2-0.5-0.4-0.5
Condit. Reinf. lever presses0.10.10.20.0-0.30.1-0.00.0-0.3-0.2-0.2-0.20.0-0.10.3-0.40.40.4-0.30.3-0.40.1-0.4-0.0-0.4-0.2
Time in familiar zone, hab. session 12.72.54.6-0.3-1.8-0.30.4-0.4-2.0-1.9-1.9-1.9-1.2-1.9-0.1-1.61.62.0-2.02.0-1.9-0.6-1.9-1.3-2.2-1.8
Time in novel zone, hab. session 11.00.91.80.61.3-0.30.3-0.31.30.91.31.00.31.0-0.41.2-1.2-1.11.3-1.31.3-0.11.30.41.30.8
Total zone transitions, hab. session 12.43.46.52.32.5-1.81.7-1.72.20.92.10.8-0.60.9-1.92.5-2.5-1.22.4-2.32.3-1.52.3-0.52.00.5
Total locomotion distance, hab. session 11.01.53.11.21.6-0.60.6-0.61.61.11.51.00.31.1-0.61.7-1.7-1.31.6-1.61.4-0.31.40.31.50.8
Locomotion velocity, hab. session 11.31.93.91.31.8-0.60.6-0.61.81.31.71.20.41.3-0.72.0-2.0-1.51.8-1.81.7-0.31.70.41.71.0
Time in familiar zone, hab. session 21.41.54.21.91.2-1.71.8-1.80.7-0.30.7-0.4-1.3-0.3-2.11.3-1.30.11.1-1.01.2-1.71.2-1.20.6-0.5
Time in novel zone, hab. session 20.40.41.6-1.3-0.50.9-1.01.0-0.20.3-0.30.30.70.21.0-0.60.6-0.2-0.40.4-0.60.8-0.60.7-0.10.4
Total zone transitions, hab. session 21.82.34.31.72.1-1.11.1-1.11.90.91.81.0-0.11.0-1.32.1-2.0-1.32.0-2.02.0-0.92.0-0.11.70.6
Total locomotion distance, hab. session 21.21.63.01.31.7-0.90.9-0.91.60.81.60.8-0.10.9-1.11.7-1.7-1.11.7-1.61.7-0.71.7-0.01.50.5
Locomotion velocity, hab. session 21.01.42.71.21.6-0.70.7-0.71.50.91.50.80.00.9-0.91.6-1.6-1.11.5-1.51.6-0.51.60.11.40.6
Novel to familiar place preference ratio0.00.00.20.50.2-0.10.1-0.10.20.20.10.20.10.20.10.3-0.3-0.20.2-0.20.10.10.10.10.10.1
Novelty place preference0.30.30.90.90.6-0.50.5-0.50.60.40.60.3-0.00.4-0.30.8-0.8-0.50.7-0.70.6-0.30.6-0.00.50.2
Time in novel zone, NPP test0.20.20.50.70.6-0.30.3-0.30.60.50.50.40.10.4-0.20.7-0.7-0.50.6-0.60.5-0.10.50.10.50.3
Total zone transitions, NPP test1.62.24.31.32.1-1.01.0-1.01.91.11.81.1-0.01.1-1.32.0-2.0-1.42.0-2.01.9-0.81.90.11.90.8
Total locomotion distance, NPP test1.11.52.81.51.7-0.91.0-1.01.50.81.50.7-0.10.8-1.11.7-1.7-1.01.6-1.61.5-0.71.5-0.11.30.4
Locomotion velocity, NPP test1.01.52.81.51.7-0.80.8-0.81.51.01.50.80.00.9-0.91.7-1.7-1.11.6-1.61.5-0.51.50.11.40.6
Pavlov. Cond. lever latency0.20.31.1-1.0-0.60.6-0.70.7-0.5-0.1-0.5-0.00.3-0.10.6-0.60.60.1-0.60.6-0.50.5-0.50.3-0.30.1
Pavlov. Cond. magazine entry latency0.10.10.20.2-0.30.10.1-0.1-0.3-0.3-0.3-0.3-0.1-0.30.1-0.40.40.3-0.30.4-0.4-0.0-0.4-0.2-0.4-0.3
Pavlov. Cond. change in total contacts0.00.00.60.80.1-0.10.0-0.00.20.10.10.10.20.20.10.1-0.1-0.10.1-0.10.10.10.10.10.00.0
Pavlov. Cond. index score0.00.00.10.2-0.00.2-0.00.00.00.10.00.00.20.10.2-0.20.20.0-0.10.1-0.10.2-0.10.1-0.10.1
Pavlov. Cond. latency score0.10.10.30.5-0.2-0.20.4-0.4-0.3-0.4-0.2-0.4-0.3-0.4-0.1-0.30.30.5-0.30.3-0.3-0.3-0.3-0.4-0.5-0.5
Pavlov. Cond. lever contacts0.40.50.80.60.80.2-0.10.10.90.80.90.80.60.90.10.6-0.6-0.80.8-0.80.70.30.70.60.80.7
Pavlov. Cond. magazine entry number0.00.00.2-0.5-0.30.0-0.20.2-0.3-0.1-0.3-0.2-0.1-0.20.1-0.20.20.2-0.30.2-0.30.1-0.3-0.1-0.2-0.1
Pavlov. Cond. intertrial magazine entries0.91.12.20.81.1-0.20.1-0.11.31.21.01.10.61.1-0.41.5-1.5-1.41.4-1.41.30.11.30.61.30.9
Pavlov. Cond. lever-magazine prob. diff.0.10.20.40.30.40.4-0.20.20.50.60.50.60.60.60.30.2-0.2-0.50.4-0.40.30.40.30.50.50.6
Pavlov. Cond. response bias0.70.91.50.51.00.4-0.20.21.21.21.11.20.81.20.10.9-0.9-1.21.1-1.10.90.50.90.91.21.2
Bone: apparent density0.91.53.2-0.5-1.60.7-0.70.7-1.4-0.8-1.4-0.90.1-0.81.3-1.51.51.0-1.71.7-1.80.7-1.8-0.1-1.7-0.8
Bone surface0.50.92.50.3-1.1-0.00.1-0.1-1.1-1.0-0.9-1.1-0.4-0.80.5-1.01.01.0-1.31.3-1.20.0-1.2-0.6-1.6-1.2
Bone volume0.81.33.01.0-1.0-0.80.8-0.8-1.2-1.5-1.0-1.5-1.1-1.3-0.1-0.70.81.4-1.21.3-1.1-0.7-1.1-1.2-1.7-1.7
Bone: connectivity density1.62.46.6-1.7-1.72.1-2.02.0-1.20.1-1.20.11.40.12.6-1.81.80.2-1.71.6-1.92.1-1.91.3-1.30.3
Bone: cortical apparent density0.10.10.2-0.20.30.2-0.10.10.40.40.30.40.30.40.10.3-0.3-0.50.4-0.40.30.20.20.30.40.4
Bone: cortical area6.59.818.51.1-2.9-2.12.2-2.2-3.4-4.1-3.2-4.2-3.3-3.9-1.3-2.32.34.1-3.23.3-2.8-2.4-2.8-3.5-4.0-4.3
Bone: cortical porosity1.11.24.22.11.3-1.21.1-1.11.10.41.10.3-0.40.5-1.11.5-1.5-0.51.2-1.21.3-0.91.3-0.40.80.0
Bone: cortical porosity1.41.56.12.51.4-1.51.5-1.51.20.21.20.1-0.60.4-1.31.6-1.6-0.41.3-1.21.4-1.11.3-0.70.8-0.3
Bone: cortical thickness3.05.09.40.1-2.5-0.91.0-1.0-2.7-2.8-2.6-2.8-1.9-2.7-0.2-2.02.02.9-2.62.6-2.5-1.1-2.4-2.1-3.1-2.8
Bone: cortical thickness3.44.07.4-1.1-2.5-0.2-0.10.1-2.5-2.2-2.5-2.2-1.1-2.10.6-2.32.42.5-2.62.6-2.5-0.2-2.5-1.2-2.7-2.0
Bone: cortical tissue density0.20.30.6-0.10.60.2-0.20.20.70.70.60.70.50.70.10.6-0.6-0.80.7-0.70.60.30.50.50.80.7
Bone: elastic displacement0.70.71.40.51.10.0-0.00.01.10.91.11.00.61.1-0.01.0-1.0-1.11.1-1.11.20.31.10.61.00.7
Bone: elastic work0.40.51.00.4-0.8-0.40.4-0.4-0.8-0.9-0.8-0.9-0.6-0.8-0.1-0.60.60.9-0.80.8-0.7-0.4-0.7-0.7-1.0-1.0
Bone: endosteal estimation4.08.716.30.6-2.6-2.12.0-2.0-3.2-4.0-3.0-3.9-3.4-3.8-1.6-2.32.34.0-2.93.0-2.5-2.5-2.4-3.5-3.5-4.0
Bone: endosteal perimeter2.75.510.20.3-2.0-1.61.6-1.6-2.5-3.2-2.4-3.1-2.7-3.1-1.3-1.81.93.2-2.32.4-2.0-2.0-1.9-2.7-2.8-3.1
Bone: final force6.210.217.60.0-3.4-1.41.4-1.4-3.8-4.0-3.7-4.1-3.0-4.0-0.7-2.92.94.2-3.63.7-3.4-1.9-3.3-3.2-4.1-4.0
Bone: final moment5.69.216.00.3-3.1-1.61.6-1.6-3.5-3.9-3.4-4.0-3.0-3.8-0.9-2.62.64.0-3.33.4-3.1-2.0-3.0-3.2-3.9-3.9
Bone: marrow area3.88.215.40.5-2.5-2.01.9-1.9-3.1-3.9-2.9-3.8-3.3-3.7-1.6-2.22.33.9-2.82.9-2.4-2.4-2.3-3.3-3.4-3.9
Bone: maximum diameter2.74.99.91.0-1.5-2.12.0-2.0-2.1-3.1-1.9-3.0-2.7-2.8-1.6-1.31.32.9-1.81.9-1.5-2.3-1.4-2.8-2.5-3.2
Bone: maximum force8.414.626.1-0.0-4.3-1.31.3-1.3-4.6-4.7-4.5-4.8-3.2-4.6-0.4-3.73.85.0-4.54.6-4.2-1.8-4.2-3.5-5.1-4.6
Bone: maximum moment7.412.923.20.3-3.9-1.51.5-1.5-4.3-4.5-4.2-4.6-3.2-4.4-0.5-3.33.44.7-4.14.2-3.9-1.9-3.8-3.4-4.8-4.5
Bone: minimum diameter5.810.721.41.8-2.6-2.62.7-2.7-3.3-4.4-3.1-4.4-3.8-4.1-2.0-2.12.14.3-3.03.1-2.6-3.0-2.5-4.0-3.9-4.6
Bone: periosteal estimation7.415.027.40.9-3.6-2.52.5-2.5-4.3-5.2-4.0-5.1-4.2-4.9-1.7-3.03.15.2-4.04.1-3.5-3.0-3.4-4.4-4.9-5.2
Bone: periosteal perimeter3.86.312.21.0-2.1-1.91.9-1.9-2.6-3.4-2.4-3.4-2.8-3.2-1.3-1.71.83.3-2.42.5-2.1-2.2-2.0-3.0-3.1-3.5
Bone: post-yield work2.94.07.0-1.1-2.5-0.0-0.10.1-2.5-2.1-2.5-2.2-1.1-2.20.5-2.32.32.4-2.62.6-2.6-0.3-2.6-1.2-2.6-1.9
Bone: stiffness7.411.720.3-0.4-3.9-1.01.0-1.0-4.3-4.1-4.1-4.2-2.8-4.2-0.3-3.53.64.4-4.14.1-3.9-1.5-3.8-3.0-4.5-3.9
Bone: tissue strength0.90.92.0-0.7-1.30.7-0.60.6-1.2-0.6-1.3-0.60.0-0.70.8-1.21.20.8-1.21.2-1.40.5-1.4-0.0-1.0-0.3
Bone: trabecular number2.33.67.3-1.6-2.51.2-1.21.2-2.3-1.2-2.3-1.30.2-1.31.8-2.42.41.6-2.62.5-2.71.1-2.70.0-2.3-0.9
Bone: trabecular spacing1.01.42.71.61.4-1.21.4-1.41.10.21.30.2-0.70.3-1.61.4-1.4-0.51.4-1.31.5-1.21.5-0.61.0-0.1
Bone: trabecular thickness0.10.20.70.3-0.50.4-0.40.4-0.3-0.0-0.4-0.10.3-0.00.8-0.40.40.1-0.50.5-0.60.5-0.70.2-0.5-0.1
Bone: trabecular tissue density1.11.62.6-0.6-1.4-0.10.2-0.2-1.6-1.6-1.4-1.5-1.0-1.5-0.1-1.51.51.6-1.51.5-1.3-0.5-1.3-1.0-1.6-1.4
Breakpoint value in progressive ratio session0.40.40.80.90.8-0.50.2-0.20.80.40.70.4-0.00.4-0.50.9-0.9-0.60.8-0.80.9-0.30.80.10.80.4
Distance traveled before self-admin0.20.20.40.50.5-0.60.4-0.40.4-0.40.40.0-0.4-0.1-0.50.6-0.6-0.10.3-0.30.4-0.50.4-0.30.4-0.2
Distance traveled after self-admin0.80.92.21.40.3-1.41.5-1.5-0.2-0.9-0.0-1.0-1.4-1.0-1.30.2-0.20.8-0.00.10.2-1.50.1-1.4-0.4-1.1
Delta time in closed arm before/after self-admin0.70.71.2-0.3-1.00.0-0.10.1-1.0-0.9-1.0-0.9-0.4-0.90.4-1.01.01.0-1.11.1-1.1-0.1-1.0-0.5-1.1-0.9
Delta time in open arm before/after self-admin1.71.64.71.90.8-2.21.8-1.80.3-0.60.3-0.8-1.7-0.8-2.11.3-1.30.30.7-0.60.7-2.00.6-1.60.3-0.8
Diff in mean of infusions in LGA sessions2.52.85.00.41.81.1-0.80.82.12.12.12.11.72.20.61.4-1.4-2.21.8-1.81.71.11.71.72.01.9
Extinction: sum of active levers before priming1.81.83.91.51.8-0.80.7-0.71.71.01.60.90.11.0-1.02.0-2.0-1.31.8-1.81.7-0.61.70.11.60.8
Active lever presses in extinction session 60.50.51.00.41.0-0.40.5-0.50.80.40.90.50.00.5-0.41.0-1.0-0.70.8-0.80.9-0.30.90.10.70.2
Delta distance traveled before/after self-admin0.00.00.20.1-0.10.4-0.00.0-0.20.4-0.0-0.00.20.10.1-0.30.30.0-0.10.0-0.10.2-0.10.1-0.20.1
Delta ambulatory time before/after self-admin0.30.31.11.10.3-0.71.0-1.00.1-0.10.1-0.4-0.7-0.3-1.00.3-0.30.30.3-0.30.5-0.80.4-0.8-0.0-0.5
Time in closed arm before self-admin1.92.25.2-2.3-1.32.2-2.22.2-0.90.6-0.90.61.70.62.1-1.41.4-0.2-1.01.0-1.22.2-1.11.7-0.61.1
Time in closed arm after self-admin4.54.710.2-3.2-2.42.8-2.82.8-1.9-0.0-1.90.01.7-0.13.1-2.82.80.6-2.32.2-2.52.6-2.41.6-1.60.4
Time in open arm before self-admin0.10.10.3-0.00.50.40.1-0.10.50.40.60.40.30.50.30.2-0.2-0.50.3-0.30.50.20.40.30.30.1
Time in open arm after self-admin3.23.68.83.01.5-2.92.9-2.90.9-0.71.0-0.9-2.2-0.8-2.91.9-1.90.31.3-1.21.5-2.81.4-2.10.6-1.2
Sum of active levers in priming session hrs 5-60.10.10.2-0.4-0.00.2-0.40.40.1-0.0-0.00.20.30.20.5-0.00.0-0.2-0.10.1-0.20.3-0.10.30.00.2
Time to tail flick, vehicle, before self-admin0.40.40.60.10.70.2-0.20.20.70.80.70.70.50.7-0.20.6-0.6-0.70.8-0.80.70.20.80.50.80.7
Time to tail flick, vehicle, after self-admin2.42.54.8-1.01.12.2-1.81.81.32.01.52.02.22.11.40.3-0.4-1.91.0-1.01.01.91.12.21.31.9
Time to tail flick, test, before self-admin0.20.20.8-0.6-0.20.9-0.70.70.10.30.00.50.70.50.6-0.10.1-0.5-0.0-0.0-0.00.7-0.10.70.20.5
Time to tail flick, test, after self-admin0.40.41.1-0.8-0.21.1-0.90.9-0.10.9-0.00.50.90.50.9-0.30.3-0.4-0.10.1-0.31.0-0.30.80.00.7
Delta time to tail flick, vehicle, before/after SA0.70.71.30.00.90.9-0.60.61.01.01.11.11.01.10.50.5-0.5-1.10.7-0.80.80.70.81.00.90.9
Delta time to tail flick, test, before/after SA0.20.10.30.4-0.1-0.30.4-0.4-0.4-0.1-0.2-0.5-0.4-0.5-0.3-0.20.20.5-0.30.3-0.3-0.3-0.3-0.5-0.5-0.5
Ambulatory time before self-admin0.00.00.1-0.2-0.1-0.20.0-0.0-0.1-0.4-0.1-0.1-0.1-0.20.1-0.10.10.2-0.20.2-0.2-0.0-0.2-0.1-0.1-0.1
Ambulatory time after self-admin1.21.33.92.00.8-1.61.9-1.90.4-0.50.5-0.6-1.4-0.6-1.80.9-0.80.40.7-0.60.9-1.70.8-1.40.2-0.8
Total heroin consumption0.10.10.40.30.0-0.70.3-0.30.0-0.2-0.1-0.2-0.4-0.3-0.50.3-0.30.10.0-0.00.2-0.50.1-0.30.1-0.2
Area under the delay curve0.00.00.10.3-0.00.1-0.20.20.20.30.00.30.30.30.20.2-0.2-0.30.1-0.1-0.00.20.00.30.20.4
Delay disc. indifference point, 0s delay1.11.22.00.0-1.0-0.90.8-0.8-1.0-1.4-1.1-1.4-1.3-1.4-0.5-0.90.91.4-1.01.0-1.0-1.1-1.0-1.3-1.1-1.4
Delay disc. indifference point, 16s delay0.50.51.00.20.8-0.40.1-0.10.90.70.70.60.10.5-0.61.0-1.0-0.70.9-0.90.8-0.20.80.20.90.6
Delay disc. indifference point, 2s delay0.10.10.30.40.00.3-0.30.30.20.30.00.30.50.40.50.1-0.1-0.30.1-0.1-0.00.5-0.10.50.10.4
Delay disc. indifference point, 24s delay2.12.03.7-0.31.21.3-1.31.31.41.71.51.91.81.90.90.9-0.9-1.71.2-1.21.31.41.41.81.51.8
Delay disc. indifference point, 4s delay0.10.20.60.2-0.60.2-0.10.1-0.4-0.2-0.4-0.30.1-0.20.6-0.30.30.3-0.50.5-0.70.2-0.70.0-0.5-0.2
Delay disc. indifference point, 8s delay0.10.10.2-0.2-0.20.4-0.30.3-0.00.2-0.20.30.30.20.3-0.10.1-0.1-0.10.0-0.20.4-0.20.40.20.4
Delay discount exponential model param0.10.20.4-0.20.0-0.50.5-0.5-0.3-0.5-0.1-0.5-0.6-0.5-0.5-0.20.20.4-0.20.2-0.0-0.5-0.0-0.6-0.3-0.6
Delay discount hyperbolic model param0.10.10.3-0.20.0-0.40.4-0.4-0.2-0.4-0.1-0.4-0.6-0.4-0.4-0.10.20.4-0.10.20.0-0.50.0-0.5-0.2-0.5
Fecal boli incidents, locomotor time 10.10.10.40.00.1-0.20.2-0.2-0.2-0.4-0.1-0.3-0.4-0.3-0.60.0-0.00.1-0.00.10.3-0.50.3-0.4-0.1-0.4
Change in fecal boli incidents, locomotor task0.40.41.50.90.1-1.11.2-1.20.2-0.40.0-0.4-0.8-0.4-0.60.4-0.40.30.2-0.2-0.1-0.9-0.0-0.80.0-0.6
Time >=10cm from walls, locomotor time 10.70.71.5-0.00.80.4-0.20.20.81.01.01.10.91.10.10.8-0.9-1.10.9-0.90.80.70.80.91.01.2
Bouts of movement, locomotor time 10.10.10.20.1-0.50.0-0.20.2-0.4-0.0-0.4-0.3-0.1-0.30.1-0.30.20.3-0.30.3-0.50.0-0.4-0.2-0.4-0.2
Total resting periods, locomotor time 10.20.20.5-0.3-0.50.7-0.70.7-0.10.4-0.10.20.50.20.6-0.20.2-0.2-0.30.2-0.50.6-0.40.4-0.10.3
Rest time, locomotor task time 10.70.82.2-0.9-1.30.9-0.70.7-0.9-0.5-1.0-0.50.0-0.61.0-1.11.10.6-1.21.1-1.50.4-1.40.0-0.9-0.4
Distance moved, locomotor task time 10.50.61.30.4-0.2-0.91.0-1.0-0.7-0.9-0.5-1.0-1.0-0.9-0.8-0.60.61.2-0.40.5-0.3-0.8-0.3-1.0-0.7-0.9
Vertical activity count, locomotor time 10.70.71.50.9-0.1-1.21.2-1.2-0.7-0.9-0.5-1.0-1.2-1.0-0.9-0.20.31.0-0.30.4-0.3-1.1-0.4-1.2-0.7-1.1
Time >=10cm from walls, locomotor time 21.61.72.8-0.6-1.6-0.00.3-0.3-1.6-1.5-1.5-1.5-0.9-1.50.1-1.61.61.6-1.61.7-1.6-0.4-1.6-0.9-1.7-1.4
Bouts of movement, locomotor time 20.40.51.10.00.40.5-0.60.60.70.80.50.90.90.90.70.5-0.5-0.80.5-0.60.30.80.40.90.81.1
Total resting periods, locomotor time 20.40.41.1-0.10.10.6-0.80.80.60.70.30.80.90.80.90.4-0.4-0.80.3-0.40.10.90.10.90.61.0
Rest time, locomotor task time 21.51.74.7-2.2-1.71.5-1.61.6-1.1-0.3-1.3-0.30.6-0.51.7-1.41.40.5-1.51.4-2.01.1-1.90.6-0.90.1
Distance moved, locomotor task time 21.01.22.40.1-0.7-0.60.9-0.9-1.3-1.4-1.0-1.4-1.1-1.4-0.6-1.21.21.6-1.11.1-0.9-0.8-0.9-1.1-1.3-1.2
Vertical activity count, locomotor time 22.73.05.20.5-1.1-1.41.5-1.5-1.9-2.3-1.6-2.3-2.1-2.3-1.2-1.31.42.2-1.51.6-1.3-1.6-1.4-2.1-2.0-2.2
Weight adjusted by age0.50.50.90.50.90.1-0.00.01.00.90.80.90.60.90.10.9-0.9-0.90.9-0.90.70.30.90.60.90.7
Seeking ratio, delayed vs. immediate footshock1.51.73.80.3-1.3-1.01.0-1.0-1.3-1.6-1.5-1.7-1.8-1.9-0.9-0.80.81.6-1.11.2-1.3-1.5-1.2-1.7-1.0-1.4
Locomotion in novel chamber0.60.72.81.10.5-1.71.3-1.30.3-0.20.2-0.5-1.0-0.4-1.40.9-0.90.20.6-0.60.6-1.20.7-1.00.2-0.3
Locomotion in novel chamber post-restriction0.40.50.90.4-0.9-0.60.3-0.3-0.9-0.6-0.9-0.9-0.6-0.9-0.0-0.30.30.9-0.80.8-0.7-0.4-0.9-0.7-0.9-0.8
Progressive ratio0.00.00.2-0.4-0.30.3-0.20.2-0.20.0-0.10.00.1-0.10.0-0.10.1-0.0-0.10.1-0.10.1-0.00.1-0.10.1
Food seeking constrained by brief footshock1.82.24.1-1.5-2.00.5-0.50.5-2.0-1.4-1.8-1.4-0.3-1.30.9-2.02.01.5-1.91.9-2.00.4-1.9-0.4-1.9-1.0
Seeking ratio, punishment vs. effort0.20.20.4-0.6-0.50.2-0.50.5-0.5-0.3-0.4-0.20.2-0.20.6-0.60.60.3-0.60.6-0.60.4-0.70.2-0.4-0.1
Run reversals in cocaine runway, females0.50.51.4-0.20.40.8-0.70.70.50.70.50.91.21.10.80.0-0.0-0.80.4-0.40.51.20.51.10.30.7
Run reversals in cocaine runway, males2.62.56.21.22.20.10.4-0.42.01.42.11.60.71.7-0.91.7-1.7-1.72.1-2.12.5-0.02.20.72.01.2
Latency to leave start box in cocaine runway0.30.31.3-1.2-0.10.7-0.90.90.20.60.30.60.80.50.8-0.10.1-0.6-0.0-0.0-0.20.8-0.10.80.30.7
Latency to leave start box in cocaine runway, F0.10.10.8-0.90.10.1-0.10.10.20.30.30.30.10.1-0.10.2-0.2-0.30.2-0.20.10.00.10.20.40.4
Latency to leave start box in cocaine runway, M0.50.51.6-0.8-0.70.8-1.11.1-0.40.1-0.50.10.80.11.3-0.70.7-0.0-0.70.7-1.00.9-0.70.7-0.50.3
Cd content in liver0.00.00.1-0.2-0.1-0.10.1-0.1-0.2-0.0-0.2-0.1-0.1-0.2-0.2-0.10.10.2-0.10.1-0.1-0.10.1-0.1-0.1-0.1
Co content in liver0.91.13.41.81.2-1.21.2-1.21.10.21.10.2-0.50.4-1.21.4-1.4-0.51.2-1.11.3-1.01.3-0.50.8-0.1
Cu content in liver2.53.05.52.12.3-1.81.8-1.81.70.41.90.4-0.90.5-2.22.2-2.2-0.82.1-2.02.3-1.72.3-0.81.60.1
Fe content in liver0.10.10.40.30.40.1-0.10.10.40.60.40.40.40.50.10.3-0.3-0.40.4-0.40.50.30.40.40.40.4
K content in liver0.10.10.40.10.3-0.20.2-0.20.40.20.40.2-0.10.2-0.40.4-0.4-0.30.5-0.50.6-0.20.6-0.00.40.2
Mg content in liver0.10.10.30.20.1-0.30.3-0.30.1-0.10.1-0.1-0.3-0.1-0.50.2-0.20.00.3-0.20.4-0.40.4-0.30.2-0.1
Mn content in liver1.51.73.9-0.60.11.7-1.71.70.71.80.61.62.01.61.70.0-0.1-1.50.4-0.50.21.90.22.00.91.8
Na content in liver0.10.20.30.30.50.3-0.30.30.40.50.40.50.40.50.20.2-0.2-0.50.4-0.40.50.40.50.40.40.5
Rb content in liver0.91.22.50.8-0.5-1.31.3-1.3-0.8-1.5-0.6-1.4-1.5-1.3-1.1-0.20.21.3-0.60.7-0.4-1.4-0.4-1.5-1.0-1.6
Se content in liver0.80.92.9-1.7-0.41.5-1.51.5-0.30.7-0.30.71.30.61.4-0.80.8-0.4-0.40.3-0.31.5-0.31.2-0.10.8
Sr content in liver0.10.10.1-0.3-0.40.0-0.00.0-0.4-0.3-0.4-0.3-0.1-0.30.0-0.40.40.3-0.30.3-0.2-0.0-0.2-0.2-0.4-0.2
Zn content in liver4.14.58.32.82.6-2.52.5-2.52.00.22.20.3-1.40.4-2.92.7-2.7-0.82.4-2.32.6-2.32.5-1.31.8-0.1