Tmod2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000010447 0.61 0.11 0.0e+00 0.22 0.34 0.38 0.37 4.3e-12 3.1e-19 2.9e-21 8.3e-21
2 Brain gene expression ENSRNOG00000010447 0.62 0.1 0.0e+00 0.44 0.56 0.57 0.56 4.5e-44 9.7e-62 2.1e-63 6.9e-63
3 Brain mRNA stability ENSRNOG00000010447 0.15 0.07 3.5e-10 0.08 0.11 0.11 0.11 3.5e-08 3.6e-10 1.8e-10 5.1e-10
4 IL gene expression ENSRNOG00000010447 0.68 0.12 1.1e-07 0.21 0.13 0.12 0.18 9.4e-06 4.7e-04 9.6e-04 3.9e-05
5 LHb gene expression ENSRNOG00000010447 0.64 0.13 3.6e-09 0.33 0.27 0.33 0.31 1.1e-08 3.3e-07 1.1e-08 5.1e-08
6 NAcc gene expression ENSRNOG00000010447 0.3 0.13 1.7e-11 0.11 0.14 0.16 0.18 1.5e-08 9.1e-11 4.0e-12 2.6e-13
7 OFC gene expression ENSRNOG00000010447 0.42 0.16 7.5e-05 0.18 0.08 0.1 0.15 4.5e-05 6.4e-03 2.7e-03 1.8e-04
8 OFC mRNA stability ENSRNOG00000010447 0.3 0.14 6.1e-04 0.1 0.06 0.08 0.12 2.1e-03 1.4e-02 7.3e-03 1.1e-03
9 PL alternative TSS ENSRNOT00000118239 0.06 0.04 4.3e-03 0.02 0.03 0.03 0.03 2.0e-02 1.5e-03 1.7e-03 3.7e-03
10 PL gene expression ENSRNOG00000010447 0.94 0.02 0.0e+00 0.14 0.17 0.31 0.31 1.8e-10 4.4e-13 1.1e-23 3.5e-24

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail1.85.915.6-2.0-1.8-3.1-0.2-2.7-2.4-2.2-2.43.9-1.8
BMI without tail2.34.87.6-2.6-2.4-2.7-2.0-2.8-1.7-1.5-1.61.9-2.3
Body weight1.98.018.7-2.6-2.4-3.9-0.8-3.4-2.2-2.3-2.34.3-2.3
Epididymis fat weight1.02.45.70.50.40.6-1.30.32.42.42.4-1.91.0
Glucose0.30.40.90.60.71.00.40.80.60.60.7-0.70.3
Heart weight0.30.51.1-0.9-0.5-0.9-0.5-0.80.1-0.0-0.01.0-1.0
Left kidney weight0.30.82.6-0.8-0.7-1.2-0.0-1.1-0.6-0.6-0.71.6-0.7
Right kidney weight0.51.32.3-1.3-1.2-1.5-0.8-1.5-0.9-1.0-1.01.1-1.0
Tail length1.13.46.2-2.3-2.4-2.1-2.5-2.2-0.9-1.0-0.90.4-2.1
Length with tail0.72.75.1-1.9-1.9-2.3-1.3-2.0-1.0-1.3-1.11.6-1.7
Length without tail0.51.15.00.40.4-0.81.7-0.1-0.6-0.8-0.72.20.4
Liver weight, left0.10.21.1-0.0-0.0-0.30.8-0.1-0.2-0.3-0.21.1-0.1
Liver weight, right0.61.01.9-1.2-1.1-1.4-0.8-1.3-0.4-0.4-0.41.2-1.1
Parametrial fat weight0.20.31.3-0.6-0.6-0.3-1.1-0.70.20.10.1-0.4-0.6
Retroperitoneal fat weight0.31.02.9-0.7-0.7-0.9-1.7-1.01.21.21.3-0.3-0.3
Intraocular pressure0.20.31.1-0.7-0.2-0.5-0.1-0.40.10.10.11.0-0.8
Extensor digitorum longus weight2.08.010.3-3.1-3.1-3.2-2.5-3.2-2.6-2.7-2.62.0-3.1
Soleus weight8.524.731.4-5.0-4.9-5.3-2.7-5.0-5.6-5.6-5.64.4-5.1
Tibialis anterior weight3.311.517.3-3.2-3.1-3.3-1.1-2.9-4.2-4.2-4.13.4-3.5
Tibia length0.61.77.61.11.1-0.32.80.6-0.4-0.4-0.42.21.2
Number of licking bursts1.72.04.1-1.2-1.3-1.3-0.5-1.2-1.9-2.0-2.01.0-1.1
Food consumed during 24 hour testing period2.12.59.6-0.10.0-1.11.9-0.4-1.8-1.9-1.93.1-0.4
Times rat made contact with spout0.80.93.4-0.00.1-0.61.3-0.1-1.0-1.1-1.11.8-0.2
Mean time between licks in bursts0.40.51.00.80.80.60.70.60.60.60.6-0.61.0
Mean num. licks in bursts1.01.31.91.11.30.81.41.11.21.31.30.40.9
Std. dev. time between licks in bursts1.31.62.4-1.3-1.5-1.1-1.6-1.5-1.3-1.4-1.4-0.3-0.9
Water consumed over 24 hours1.11.34.0-0.4-0.4-1.00.9-0.6-1.4-1.5-1.52.0-0.6
Indifference point 0 sec0.10.10.3-0.1-0.10.10.40.2-0.3-0.3-0.40.5-0.2
Indifference point AUC0.40.51.9-0.6-0.8-0.7-1.4-0.90.30.40.4-0.6-0.1
Indifference point function ln k0.30.41.10.30.40.41.10.6-0.7-0.7-0.80.8-0.3
Indifference point function log k0.30.41.10.30.40.41.10.6-0.7-0.7-0.80.8-0.3
Delay discounting total patch changes 0 sec0.10.10.40.10.10.10.60.3-0.1-0.1-0.20.6-0.1
Delay discounting total patch changes 12 sec0.20.30.70.10.00.1-0.5-0.00.70.70.6-0.90.5
Delay discounting total patch changes 18 sec0.50.61.10.90.90.71.00.80.70.70.8-0.21.0
Delay discounting total patch changes 24 sec0.91.13.6-1.4-1.4-0.9-1.9-1.20.0-0.10.00.0-1.3
Delay discounting total patch changes 6 sec0.50.82.8-1.2-1.2-0.5-1.7-0.8-0.00.0-0.1-0.7-1.0
Delay discounting time to switch 0 sec0.60.92.20.90.91.20.20.80.80.70.8-1.50.9
Delay discounting water rate 0 sec0.91.45.7-0.8-0.7-1.30.4-0.7-1.1-1.0-1.12.4-1.2
Delay discounting water rate 12 sec1.42.13.6-1.5-1.3-1.3-0.4-1.1-1.6-1.6-1.51.9-1.9
Delay discounting water rate 18 sec0.20.31.0-0.5-0.2-0.4-0.3-0.20.40.40.41.0-0.9
Delay discounting water rate 24 sec0.10.10.4-0.4-0.3-0.1-0.20.10.00.00.00.2-0.7
Delay discounting water rate 6 sec1.52.23.3-1.6-1.4-1.4-0.5-1.2-1.5-1.7-1.61.7-1.8
Locomotor activity0.10.10.50.10.1-0.20.3-0.1-0.1-0.4-0.30.70.3
Locomotor testing distance0.10.10.40.30.40.20.60.30.1-0.2-0.10.70.2
Locomotor testing rearing0.00.00.20.20.20.20.20.30.1-0.1-0.10.4-0.0
Light reinforcement 12.34.27.7-2.0-2.1-2.8-1.2-2.6-1.8-1.7-1.82.3-1.7
Light reinforcement 21.62.25.11.91.81.32.31.60.50.70.6-0.42.0
Reaction time number correct0.50.71.4-0.9-0.9-0.3-1.2-0.8-1.1-0.9-0.9-0.3-0.9
Reaction time mean minus median1.62.03.51.41.61.51.11.21.91.51.6-0.71.3
Reaction time mean minus median AUC1.41.82.81.41.61.71.11.21.61.31.4-0.81.3
Reaction time num false alarms0.60.81.80.70.61.0-0.20.81.11.01.1-1.30.6
Reaction time num false alarms AUC0.70.92.30.70.61.1-0.30.91.21.11.1-1.50.6
Reaction time trials correct on left0.50.71.4-0.9-0.9-0.3-1.2-0.8-1.1-0.9-0.9-0.3-0.9
Reaction time trials on left0.50.71.4-0.9-0.8-0.2-1.2-0.7-1.0-0.8-0.8-0.5-0.9
Reaction time mean1.92.63.91.82.01.81.51.61.71.41.5-0.91.8
Reaction time mean AUC1.31.82.71.51.71.51.21.31.41.11.2-0.81.4
Median of all reaction times1.82.43.61.71.91.71.31.61.61.41.5-1.01.7
Reaction time omissions0.91.24.20.50.41.2-0.90.61.21.01.2-2.10.6
Reaction time false alarm rate1.01.52.81.11.01.20.41.21.71.51.5-1.11.0
Reaction time premature initiation rate0.30.40.9-0.7-0.5-0.7-0.6-0.8-0.1-0.2-0.20.9-0.7
Reaction time premature initiations0.60.81.4-1.0-0.9-0.8-1.2-1.1-0.6-0.6-0.60.7-1.1
Std. dev. reaction times2.02.74.21.61.81.91.01.52.11.71.8-1.21.6
Reaction time trials completed0.50.71.4-0.9-0.8-0.2-1.2-0.7-1.0-0.8-0.8-0.5-0.9
Reaction time trials AUC0.50.71.3-0.9-0.9-0.3-1.1-0.7-1.1-0.9-0.9-0.4-0.9
Social response proportion2.72.94.52.02.01.72.12.01.51.41.4-0.31.8
Social responses0.10.10.50.40.20.10.60.40.30.10.2-0.10.7
Social time0.10.20.50.50.40.50.70.70.10.10.2-0.10.5
Conditioned locomotion0.20.30.70.40.2-0.2-0.2-0.10.80.70.8-0.20.7
Cocaine response after cond. corrected0.80.93.5-0.3-0.1-0.61.2-0.1-1.1-1.1-1.11.9-0.5
Cocaine response after cond. not corrected1.21.35.90.10.3-0.61.90.1-1.0-1.1-1.12.4-0.1
Cocaine response before conditioning0.60.72.4-0.3-0.4-1.10.3-0.8-0.8-1.0-0.91.5-0.3
Saline control response1.41.93.81.61.61.82.01.90.60.60.7-0.61.3
Condit. Reinf. active minus inactive responses0.50.72.0-0.6-0.4-0.30.3-0.2-0.9-1.0-0.91.4-1.1
Condit. Reinf. active-inactive response ratio0.40.41.00.60.70.81.00.9-0.0-0.1-0.10.50.0
Condit. Reinf. active responses1.52.14.4-1.4-1.2-1.5-0.5-1.4-1.4-1.5-1.52.1-1.6
Condit. Reinf. inactive responses1.92.44.3-1.6-1.6-2.1-1.2-2.0-1.3-1.3-1.31.5-1.3
Condit. Reinf. lever presses0.50.82.30.20.5-0.01.50.3-0.9-1.0-0.91.5-0.2
Condit. Reinf. lever reinforcers received1.11.64.3-1.1-0.9-1.3-0.2-1.1-1.2-1.2-1.22.1-1.4
Pavlov. Cond. lever latency1.52.03.61.21.11.30.01.01.81.91.9-1.61.4
Pavlov. Cond. magazine entry latency1.41.63.51.41.11.60.71.50.70.70.7-1.91.5
Pavlov. Cond. change in total contacts0.30.50.7-0.6-0.5-0.6-0.0-0.5-0.8-0.9-0.80.8-0.7
Pavlov. Cond. index score0.30.41.2-0.3-0.4-0.30.1-0.2-1.1-1.1-1.10.2-0.4
Pavlov. Cond. latency score0.30.41.4-0.2-0.2-0.10.4-0.0-1.1-1.2-1.10.3-0.2
Pavlov. Cond. lever contacts1.41.93.8-1.0-1.0-1.20.2-0.9-1.9-2.0-1.91.6-1.1
Pavlov. Cond. magazine entry number0.20.31.1-0.4-0.3-0.7-0.2-0.60.10.10.11.1-0.4
Pavlov. Cond. intertrial magazine entries0.20.30.7-0.4-0.5-0.8-0.5-0.8-0.3-0.4-0.40.6-0.3
Pavlov. Cond. lever-magazine prob. diff.0.20.30.9-0.2-0.3-0.20.2-0.1-0.9-1.0-0.90.0-0.2
Pavlov. Cond. response bias0.50.71.4-0.7-0.8-0.7-0.4-0.6-1.2-1.2-1.20.3-0.7
Conditioned reinforcement - actives0.10.10.30.40.20.30.10.10.00.00.1-0.50.6
Conditioned reinforcement - inactives0.10.10.4-0.3-0.2-0.2-0.6-0.50.10.20.10.1-0.2
Conditioned locomotion1.21.42.11.41.40.71.41.11.31.31.3-0.11.3
Intermittent access intake day 1-15 change0.50.52.0-0.7-0.5-0.6-0.9-1.4-0.5-0.3-0.40.6-0.3
Intermittent access intake escalation1.11.02.6-0.9-0.7-1.1-0.6-1.6-1.1-1.0-1.11.1-0.6
Intermittent access intake escalation 21.91.93.5-1.3-1.2-1.3-0.9-1.9-1.7-1.5-1.61.1-0.9
Intermitt. access day 1 inactive lever presses0.00.00.10.10.10.0-0.00.20.20.20.2-0.20.0
Intermitt. access day 15 inactive lever presses0.20.20.70.20.1-0.2-0.5-0.20.80.90.7-0.30.3
Intermitt. access escalation Index1.41.37.1-0.10.4-0.91.5-0.3-0.9-0.9-0.82.7-0.1
Intermittent access day 1 total infusions3.43.85.22.22.22.01.72.31.81.81.8-1.62.2
Intermittent access day 15 total infusions0.50.61.51.01.10.70.80.50.40.50.5-0.41.2
Intermittent access terminal intake (last 3 days)0.30.30.80.80.80.20.90.20.10.10.10.20.9
Intermittent access total infusions2.12.43.81.91.91.61.81.80.91.00.9-0.91.9
Intermittent access day 1 locomotion3.33.44.31.91.91.51.31.92.02.02.1-1.52.0
Intermittent access day 15 total locomotion1.11.21.51.21.10.90.91.21.01.11.2-0.81.1
Intermittent access total locomotion0.70.81.51.11.10.81.21.20.60.60.7-0.50.9
Intermittent access standard deviation0.20.20.6-0.2-0.4-0.6-0.4-0.8-0.5-0.4-0.4-0.10.3
Cocaine induced anxiety0.20.21.0-0.2-0.40.0-0.7-0.1-0.2-0.2-0.2-1.0-0.1
Post-drug Anxiety0.70.84.4-0.2-0.50.5-1.50.00.50.50.5-2.1-0.1
Baseline Anxiety0.60.71.70.30.40.7-0.50.41.31.31.3-0.80.3
Lifetime Intake2.73.04.82.12.01.81.61.91.31.41.3-1.52.2
Incentive Sensitization - Responses0.10.10.20.30.10.0-0.10.10.10.40.2-0.50.5
Incentive Sensitization - Breakpoint0.10.10.30.2-0.0-0.0-0.3-0.00.20.50.3-0.60.4
Progressive ratio test 1 active lever presses0.70.71.81.11.10.51.31.00.40.40.50.01.1
Progressive ratio test 1 breakpoint0.80.92.31.21.20.51.51.10.50.50.50.01.2
Progressive ratio test 1 inactive lever presses0.60.71.00.91.00.70.70.90.70.70.7-0.61.0
Progressive ratio test 2 active lever presses0.30.30.60.70.60.30.60.50.30.40.3-0.40.8
Progressive ratio test 2 breakpoint0.20.20.50.60.50.30.50.40.10.20.2-0.40.7
Progressive ratio test 2 inactive lever presses2.22.63.92.01.71.71.31.81.31.41.3-1.52.0
Total sessions with >9 infusions0.70.71.91.11.00.71.41.0-0.0-0.0-0.0-0.51.2
Short access day 1 total inactive lever presses0.30.30.50.50.70.20.70.40.50.60.30.50.6
Short access day 10 total inactive lever presses0.00.00.2-0.2-0.20.1-0.4-0.10.20.1-0.0-0.1-0.2
Short access day 1 total infusions0.80.91.91.21.00.80.80.90.60.70.7-1.01.4
Short access day 10 total infusions3.43.86.12.42.22.22.22.51.11.11.0-1.72.3
Short access total infusions4.65.17.12.52.52.41.82.42.02.02.0-2.02.7
Short access day 1 locomotion0.20.20.3-0.3-0.1-0.60.1-0.5-0.6-0.5-0.60.4-0.1
Short access day 10 total locomotion0.00.00.20.10.1-0.00.40.3-0.2-0.3-0.1-0.10.1
Short access total locomotion1.31.42.21.41.40.91.51.40.80.70.9-0.81.4
Compulsive drug intake2.22.26.11.71.81.52.52.00.70.60.60.11.4
One hour access (0.3 mA shock)0.80.91.71.21.01.00.71.00.90.80.8-0.91.3
One hour access (shock baseline)0.10.11.00.2-0.00.1-0.3-0.1-0.10.0-0.1-1.00.6
Number of responses in last shaping day1.01.03.00.40.2-0.81.7-0.0-1.1-1.3-1.21.20.4
Context. condit. distance diff. score0.10.20.60.10.1-0.10.80.2-0.5-0.5-0.50.60.0
Locomotion velocity, session 10.91.01.5-1.1-1.1-1.2-0.8-1.2-0.8-0.8-0.81.1-1.1
Locomotion distance, session 10.81.04.0-0.9-1.2-0.5-2.0-1.0-0.4-0.4-0.4-1.3-0.6
Locomotion velocity, session 21.51.82.8-1.5-1.7-1.4-1.2-1.4-1.3-1.3-1.30.8-1.4
Locomotion distance, session 22.13.07.8-2.1-2.2-1.7-2.8-2.1-0.9-0.9-0.9-0.4-1.7
Locomotion velocity, session 31.01.12.4-1.0-1.3-0.0-1.5-0.5-0.9-1.0-1.0-1.4-1.0
Locomotion distance, session 30.91.05.4-0.3-0.40.8-1.60.20.50.50.5-2.3-0.3
Stereotopy head waving bouts, day 31.72.04.21.71.51.72.11.90.50.50.5-0.71.6
Stereotopy head waving duration, day 31.72.16.41.71.71.52.51.90.50.40.50.31.4
Locomotion velocity, session 70.10.10.50.0-0.20.2-0.20.2-0.0-0.1-0.1-0.70.1
Locomotion distance, session 70.40.50.8-0.7-0.9-0.5-0.9-0.6-0.6-0.6-0.6-0.3-0.7
Stereotopy head waving bouts, day 70.30.30.5-0.3-0.40.5-0.30.3-0.7-0.7-0.7-0.7-0.5
Stereotopy head waving duration, day 70.40.51.0-0.7-0.70.1-0.6-0.1-1.0-1.0-1.0-0.4-0.9
Locomotion velocity, session 81.82.23.6-1.8-1.9-1.1-1.8-1.4-1.4-1.4-1.40.0-1.8
Locomotion distance, session 81.62.33.9-1.7-2.0-1.4-1.9-1.5-1.4-1.5-1.4-0.3-1.5
Degree of sensitization distance0.60.62.9-0.1-0.1-1.00.9-0.5-0.7-0.7-0.71.7-0.1
Degree of sensitization stereotypy0.50.50.8-0.7-0.80.0-0.7-0.2-0.9-0.9-0.9-0.5-0.9
Condit. Reinf. active minus inactive responses3.03.35.6-2.2-2.2-2.1-2.4-2.2-1.1-1.1-1.10.7-2.1
Condit. Reinf. active-inactive response ratio0.20.21.50.00.3-0.20.70.0-0.0-0.0-0.01.2-0.3
Condit. Reinf. active responses5.46.611.0-3.1-3.3-2.7-3.3-3.0-1.9-1.8-1.90.4-2.8
Condit. Reinf. inactive responses4.14.99.7-2.6-2.9-2.0-3.1-2.4-1.7-1.7-1.7-0.4-2.2
Incentive salience index mean3.23.85.7-2.1-2.4-2.2-2.0-2.3-1.8-1.8-1.80.7-1.8
Condit. Reinf. lever presses1.62.24.0-1.2-1.7-1.5-0.8-1.5-2.0-2.0-2.00.1-0.7
Time in familiar zone, hab. session 11.11.02.1-0.7-0.8-1.0-0.3-1.0-1.4-1.5-1.40.6-0.6
Time in novel zone, hab. session 11.11.12.10.81.20.90.81.01.41.51.40.40.4
Total zone transitions, hab. session 10.91.36.0-1.0-1.2-0.3-2.4-1.00.30.40.3-1.8-0.6
Total locomotion distance, hab. session 11.11.67.6-1.0-1.1-0.2-2.8-0.90.60.70.6-1.9-0.7
Locomotion velocity, hab. session 10.81.25.4-0.8-1.1-0.2-2.3-0.80.30.40.4-1.9-0.5
Time in familiar zone, hab. session 20.10.10.4-0.10.0-0.00.3-0.0-0.3-0.3-0.30.6-0.5
Time in novel zone, hab. session 20.30.30.60.70.70.50.80.70.40.40.4-0.10.7
Total zone transitions, hab. session 22.53.311.2-2.1-2.4-1.6-3.3-2.1-0.6-0.6-0.6-1.1-1.4
Total locomotion distance, hab. session 22.22.911.0-1.8-2.2-1.4-3.3-2.0-0.3-0.3-0.3-1.4-1.1
Locomotion velocity, hab. session 21.52.18.6-1.4-1.8-1.1-2.9-1.6-0.0-0.0-0.0-1.7-0.6
Novel to familiar place preference ratio0.30.30.7-0.5-0.3-0.60.2-0.5-0.5-0.5-0.50.9-0.5
Novelty place preference0.60.61.8-0.5-0.4-0.80.5-0.6-0.8-0.8-0.81.3-0.6
Time in novel zone, NPP test0.80.83.2-0.5-0.2-0.80.8-0.5-1.0-0.9-0.91.8-0.7
Total zone transitions, NPP test1.52.26.2-1.7-1.9-1.2-2.5-1.7-0.7-0.7-0.7-0.6-1.5
Total locomotion distance, NPP test2.23.09.4-2.0-2.2-1.5-3.1-2.1-0.8-0.8-0.8-0.9-1.6
Locomotion velocity, NPP test2.02.910.9-1.8-2.2-1.2-3.3-1.9-0.5-0.6-0.6-1.7-1.3
Pavlov. Cond. lever latency2.43.14.41.72.11.81.62.02.02.02.00.11.1
Pavlov. Cond. magazine entry latency0.30.40.7-0.3-0.8-0.8-0.8-0.8-0.4-0.4-0.4-0.90.3
Pavlov. Cond. change in total contacts0.70.81.5-0.8-1.2-1.2-1.1-1.2-0.7-0.7-0.7-0.3-0.3
Pavlov. Cond. index score1.11.42.5-1.1-1.6-1.3-1.5-1.5-1.1-1.1-1.1-0.8-0.4
Pavlov. Cond. latency score1.21.52.6-1.1-1.6-1.3-1.4-1.5-1.2-1.2-1.2-0.7-0.5
Pavlov. Cond. lever contacts1.51.82.6-1.3-1.6-1.5-1.2-1.6-1.5-1.5-1.5-0.0-0.8
Pavlov. Cond. magazine entry number0.30.41.10.40.80.61.00.80.30.30.31.1-0.2
Pavlov. Cond. intertrial magazine entries2.02.45.2-2.0-1.9-1.1-2.2-1.4-1.1-1.1-1.10.2-2.3
Pavlov. Cond. lever-magazine prob. diff.1.31.62.8-1.1-1.7-1.4-1.6-1.6-1.2-1.2-1.2-0.8-0.4
Pavlov. Cond. response bias0.80.91.8-0.9-1.3-1.1-1.3-1.3-0.8-0.8-0.8-0.5-0.3
Bone: apparent density0.00.00.20.0-0.10.1-0.20.1-0.2-0.2-0.2-0.40.1
Bone surface1.22.24.2-1.3-1.4-1.3-0.6-1.1-2.0-2.1-2.00.8-1.3
Bone volume0.61.02.0-0.9-0.9-0.9-0.3-0.8-1.3-1.4-1.30.7-0.8
Bone: connectivity density0.40.64.30.1-0.10.7-1.00.30.30.30.3-2.10.3
Bone: cortical apparent density2.12.85.01.41.71.70.71.52.22.22.2-0.91.2
Bone: cortical area0.81.34.41.31.41.02.11.30.30.30.30.51.1
Bone: cortical porosity0.80.81.71.20.90.80.90.90.70.70.7-0.81.3
Bone: cortical porosity0.91.01.81.20.91.00.61.00.70.70.7-1.31.3
Bone: cortical thickness3.45.77.82.62.82.52.42.62.42.32.4-1.02.4
Bone: cortical thickness2.73.15.32.12.21.72.31.91.61.51.60.11.8
Bone: cortical tissue density1.82.44.51.31.51.50.71.42.12.12.1-0.81.1
Bone: elastic displacement0.10.10.50.00.1-0.1-0.3-0.00.50.70.60.00.1
Bone: elastic work0.20.20.40.50.50.40.40.50.60.70.60.00.5
Bone: endosteal estimation2.86.011.0-2.0-2.1-2.4-0.3-1.9-3.3-3.3-3.32.3-2.0
Bone: endosteal perimeter1.73.46.1-1.5-1.6-1.9-0.2-1.5-2.4-2.5-2.51.8-1.4
Bone: final force0.10.20.7-0.1-0.1-0.40.4-0.1-0.4-0.4-0.40.8-0.2
Bone: final moment0.10.20.80.40.5-0.00.90.30.10.10.00.70.3
Bone: marrow area2.65.510.4-1.8-1.9-2.3-0.1-1.8-3.2-3.2-3.22.3-1.8
Bone: maximum diameter2.64.89.3-1.3-1.2-2.00.9-1.3-3.0-3.0-3.03.0-1.5
Bone: maximum force0.30.51.3-0.4-0.3-0.70.4-0.4-0.9-1.0-0.91.1-0.4
Bone: maximum moment0.10.31.00.10.2-0.30.90.0-0.4-0.5-0.51.00.1
Bone: minimum diameter0.30.52.00.70.80.11.40.50.10.10.10.90.7
Bone: periosteal estimation1.32.65.1-0.9-0.9-1.40.7-0.9-2.2-2.3-2.32.1-1.1
Bone: periosteal perimeter0.50.92.1-0.6-0.5-0.60.5-0.4-1.4-1.5-1.41.0-0.7
Bone: post-yield work2.73.76.3-1.8-1.7-1.8-0.7-1.7-2.4-2.5-2.51.6-2.0
Bone: stiffness0.20.30.8-0.7-0.6-0.5-0.6-0.6-0.5-0.6-0.50.3-0.9
Bone: tissue strength0.80.71.00.80.90.90.71.01.00.91.0-0.30.7
Bone: trabecular number0.30.41.5-0.3-0.7-0.1-1.0-0.3-0.6-0.6-0.6-1.2-0.1
Bone: trabecular spacing1.01.33.20.70.80.7-0.20.61.81.81.8-0.80.8
Bone: trabecular thickness0.60.72.31.01.10.51.50.80.50.40.50.80.9
Bone: trabecular tissue density0.91.22.31.11.40.61.50.91.21.11.21.00.7
Breakpoint value in progressive ratio session1.01.11.9-0.8-1.1-1.0-0.5-1.1-1.3-1.4-1.30.7-0.6
Distance traveled before self-admin0.70.81.9-0.7-0.8-0.50.1-0.4-1.4-1.3-1.40.4-0.7
Distance traveled after self-admin1.92.13.8-1.1-1.1-1.30.2-1.2-1.9-1.9-1.91.9-0.9
Delta time in closed arm before/after self-admin1.41.31.71.31.30.81.21.11.31.31.30.01.3
Delta time in open arm before/after self-admin1.71.75.00.91.02.20.21.60.90.90.9-2.20.6
Diff in mean of infusions in LGA sessions1.11.23.3-0.1-0.3-0.70.9-0.6-1.7-1.8-1.71.20.0
Extinction: sum of active levers before priming0.40.40.90.70.70.80.90.9-0.0-0.1-0.0-0.70.6
Active lever presses in extinction session 60.50.50.9-0.5-0.7-0.4-0.4-0.6-1.0-0.9-1.00.3-0.6
Delta distance traveled before/after self-admin0.50.53.2-0.2-0.1-0.80.4-0.6-0.4-0.4-0.41.8-0.2
Delta ambulatory time before/after self-admin0.40.52.70.30.5-0.31.1-0.1-0.2-0.2-0.21.60.2
Time in closed arm before self-admin0.50.61.0-0.6-0.6-0.8-0.2-0.7-1.0-1.0-1.00.4-0.6
Time in closed arm after self-admin0.20.20.40.50.40.10.40.40.60.70.6-0.00.6
Time in open arm before self-admin0.50.62.0-0.1-0.1-0.80.9-0.3-0.9-0.8-0.91.4-0.1
Time in open arm after self-admin0.30.41.20.40.51.10.70.9-0.4-0.4-0.4-0.70.2
Sum of active levers in priming session hrs 5-60.20.20.40.30.30.30.70.2-0.3-0.4-0.30.6-0.0
Time to tail flick, vehicle, before self-admin0.70.71.1-1.0-0.9-0.5-0.9-0.8-0.9-0.9-0.90.2-1.0
Time to tail flick, vehicle, after self-admin0.80.92.3-0.0-0.2-0.31.10.2-1.5-1.5-1.50.6-0.3
Time to tail flick, test, before self-admin0.50.51.0-0.8-0.8-1.0-0.9-1.0-0.4-0.4-0.40.4-0.5
Time to tail flick, test, after self-admin1.41.42.0-1.2-1.2-1.4-0.6-1.3-1.3-1.2-1.31.1-1.0
Delta time to tail flick, vehicle, before/after SA0.20.20.6-0.0-0.2-0.30.50.1-0.7-0.7-0.80.4-0.2
Delta time to tail flick, test, before/after SA0.40.41.10.10.20.01.10.3-0.8-0.8-0.80.8-0.1
Ambulatory time before self-admin0.20.20.7-0.4-0.5-0.2-0.1-0.2-0.8-0.7-0.7-0.5-0.1
Ambulatory time after self-admin1.01.12.5-0.5-0.4-0.70.9-0.4-1.5-1.4-1.51.6-0.4
Total heroin consumption1.61.92.7-1.2-1.3-1.4-0.4-1.3-1.6-1.6-1.61.7-1.2
Area under the delay curve2.02.13.3-1.5-1.3-1.8-0.6-1.4-1.5-1.5-1.51.6-1.4
Delay disc. indifference point, 0s delay2.52.76.2-2.0-2.1-1.6-2.5-1.9-0.8-0.8-0.80.2-2.1
Delay disc. indifference point, 16s delay0.10.10.70.20.60.00.80.40.00.00.00.4-0.0
Delay disc. indifference point, 2s delay1.01.11.8-1.2-0.9-1.3-0.6-1.1-0.8-0.7-0.81.3-1.3
Delay disc. indifference point, 24s delay0.10.10.2-0.4-0.2-0.4-0.1-0.1-0.2-0.2-0.20.2-0.4
Delay disc. indifference point, 4s delay1.92.02.8-1.6-1.4-1.5-1.0-1.4-1.5-1.5-1.51.1-1.7
Delay disc. indifference point, 8s delay4.04.26.0-2.0-2.0-2.4-0.9-2.2-2.2-2.2-2.22.2-1.7
Delay discount exponential model param2.32.53.71.61.41.90.61.61.71.61.7-1.71.5
Delay discount hyperbolic model param2.02.13.11.51.21.80.51.41.51.51.5-1.71.5
Fecal boli incidents, locomotor time 11.81.94.0-1.2-1.5-2.0-0.8-1.7-1.4-1.4-1.41.2-0.8
Change in fecal boli incidents, locomotor task1.21.22.91.11.21.71.61.70.10.10.1-0.40.6
Time >=10cm from walls, locomotor time 10.40.41.0-0.3-0.5-0.6-0.1-0.5-0.9-1.0-0.90.2-0.2
Bouts of movement, locomotor time 10.40.50.9-0.7-0.7-1.0-0.6-0.9-0.5-0.6-0.50.5-0.5
Total resting periods, locomotor time 10.20.20.4-0.4-0.3-0.6-0.1-0.5-0.4-0.5-0.40.5-0.3
Rest time, locomotor task time 10.60.72.90.40.8-0.01.60.4-0.1-0.1-0.11.7-0.1
Distance moved, locomotor task time 10.50.52.4-0.6-0.7-0.1-1.6-0.60.30.30.3-1.0-0.4
Vertical activity count, locomotor time 10.20.21.1-0.4-0.5-0.1-1.0-0.30.10.10.1-0.8-0.1
Time >=10cm from walls, locomotor time 20.50.51.20.90.90.41.10.60.50.60.50.40.8
Bouts of movement, locomotor time 20.50.62.2-0.8-0.8-0.8-1.5-1.00.40.50.4-0.2-0.5
Total resting periods, locomotor time 20.40.41.4-0.7-0.6-0.7-1.2-0.90.20.40.3-0.2-0.5
Rest time, locomotor task time 21.92.23.31.61.81.51.61.71.51.51.5-0.51.3
Distance moved, locomotor task time 21.41.74.2-1.5-1.6-1.0-2.1-1.5-0.7-0.8-0.7-0.1-1.6
Vertical activity count, locomotor time 20.30.30.5-0.7-0.7-0.6-0.7-0.7-0.5-0.5-0.50.3-0.6
Weight adjusted by age2.32.64.3-1.4-1.6-2.1-0.6-1.5-1.9-1.9-1.91.3-1.4
Seeking ratio, delayed vs. immediate footshock4.75.47.8-2.3-2.5-2.2-1.3-2.3-2.8-2.8-2.81.4-2.3
Locomotion in novel chamber0.50.61.10.80.80.70.91.00.80.70.7-0.40.8
Locomotion in novel chamber post-restriction0.10.10.40.20.10.3-0.1-0.00.60.60.6-0.00.4
Progressive ratio1.01.22.8-0.9-1.1-1.7-0.5-1.4-0.9-0.9-0.91.4-0.6
Food seeking constrained by brief footshock3.74.58.0-2.0-1.8-2.2-0.5-1.9-2.3-2.3-2.32.8-2.3
Seeking ratio, punishment vs. effort0.30.41.3-0.7-0.5-0.1-0.3-0.3-0.7-0.7-0.70.4-1.1
Run reversals in cocaine runway, females1.51.52.41.51.51.21.31.51.11.31.1-0.31.1
Run reversals in cocaine runway, males2.52.43.6-1.8-1.9-1.6-1.7-1.7-1.4-1.4-1.40.6-1.8
Latency to leave start box in cocaine runway0.10.10.3-0.1-0.30.1-0.20.0-0.5-0.5-0.4-0.60.1
Latency to leave start box in cocaine runway, F0.30.30.5-0.5-0.7-0.6-0.6-0.6-0.7-0.6-0.60.0-0.3
Latency to leave start box in cocaine runway, M0.40.31.80.30.10.7-0.20.50.40.40.4-1.40.4
Cd content in liver1.71.83.4-1.6-1.7-1.5-1.8-1.6-0.8-0.8-0.80.4-1.5
Co content in liver0.30.41.0-0.5-0.4-1.0-0.7-0.90.40.40.40.7-0.2
Cu content in liver0.30.30.80.40.50.10.20.10.90.90.90.20.4
Fe content in liver0.60.71.4-0.7-0.90.2-0.8-0.0-1.0-1.0-1.0-1.2-0.7
K content in liver0.10.10.3-0.4-0.4-0.2-0.3-0.2-0.2-0.2-0.20.1-0.5
Mg content in liver1.11.11.7-1.1-1.0-1.2-0.5-1.0-1.0-1.0-1.01.2-1.3
Mn content in liver2.12.45.32.01.91.42.31.70.90.90.9-0.31.9
Na content in liver0.20.30.7-0.2-0.50.1-0.20.0-0.7-0.7-0.7-0.8-0.0
Rb content in liver1.92.34.0-1.8-1.7-1.4-1.4-1.5-1.4-1.4-1.41.0-2.0
Se content in liver1.31.62.11.31.21.40.71.41.11.11.1-1.51.4
Sr content in liver0.60.50.8-0.7-0.9-0.8-0.7-0.9-0.8-0.8-0.8-0.1-0.3
Zn content in liver0.30.40.60.60.70.10.60.30.70.70.70.40.6