Hub : Genes

Wdfy2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000010042	0.3	0.09	0.0e+00	0.16	0.16	0.17	0.17	4.3e-17	1.0e-17	4.2e-18	5.0e-18
2	Adipose	mRNA stability	ENSRNOG00000010042	0.29	0.1	2.2e-16	0.09	0.12	0.11	0.12	8.5e-10	8.3e-13	4.4e-12	7.3e-13
3	BLA	gene expression	ENSRNOG00000010042	0.16	0.08	1.3e-05	0.09	0.09	0.09	0.09	2.6e-05	1.9e-05	1.1e-05	1.2e-05
4	Brain	gene expression	ENSRNOG00000010042	0.12	0.06	2.1e-06	0.08	0.07	0.07	0.07	6.5e-08	4.8e-07	3.1e-07	2.5e-07
5	Liver	gene expression	ENSRNOG00000010042	0.38	0.11	0.0e+00	0.36	0.37	0.38	0.37	4.9e-42	4.3e-43	6.5e-44	4.7e-43
6	PL	gene expression	ENSRNOG00000010042	0.03	0.02	8.0e-03	0.02	0.01	-0	0	2.0e-02	2.2e-02	4.3e-01	2.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
BMI with tail	0.7	2.2	3.3	-1.3	-1.4	1.7	1.5	-1.8	0.8
BMI without tail	0.2	0.4	1.1	0.3	-1.1	-0.7	0.3	0.7	-0.5
Body weight	0.6	2.4	5.4	-0.5	-0.0	2.2	0.5	-2.3	1.9
Epididymis fat weight	0.1	0.1	0.4	-0.4	-0.6	-0.3	0.0	0.2	-0.3
Glucose	0.1	0.1	0.4	0.3	0.1	0.6	0.1	-0.2	0.6
Heart weight	0.2	0.3	0.7	-0.4	-0.0	0.8	0.4	-0.7	0.2
Left kidney weight	1.5	4.4	9.1	1.5	1.9	2.2	-1.1	-2.2	3.0
Right kidney weight	1.4	4.1	10.7	1.1	1.2	2.4	-0.3	-2.4	3.3
Tail length	0.5	1.5	2.6	1.6	0.9	-1.2	-1.5	1.3	-0.0
Length with tail	0.3	1.0	2.6	0.5	1.6	0.5	-1.2	-0.6	1.0
Length without tail	1.3	2.9	6.4	-1.1	1.2	2.4	0.2	-2.5	1.7
Liver weight, left	1.4	2.3	5.3	0.5	-0.4	2.1	0.5	-1.9	2.3
Liver weight, right	0.3	0.6	1.0	-0.7	-1.0	0.8	0.6	-0.8	0.4
Parametrial fat weight	1.3	2.6	4.7	-0.9	-1.3	-2.1	0.0	2.1	-2.2
Retroperitoneal fat weight	0.2	0.6	1.7	-0.5	-1.3	-0.7	0.3	0.5	-0.9
Intraocular pressure	4.4	6.3	8.4	2.7	1.6	-2.9	-2.8	2.9	-1.9
Extensor digitorum longus weight	4.8	19.3	33.7	-2.0	-1.6	5.8	3.4	-5.7	5.6
Soleus weight	1.2	3.4	6.4	-1.8	-2.2	1.9	2.5	-1.4	0.7
Tibialis anterior weight	4.7	16.2	31.6	-1.5	-0.9	5.3	2.7	-5.2	5.6
Tibia length	1.9	5.3	10.6	3.0	3.3	0.7	-3.0	-0.6	1.5
Number of licking bursts	0.3	0.4	0.8	-0.6	-0.9	0.4	0.7	-0.5	0.5
Food consumed during 24 hour testing period	0.4	0.5	1.2	1.1	0.8	-0.0	-0.9	0.2	0.4
Times rat made contact with spout	0.7	0.8	1.7	1.1	1.3	0.2	-1.1	-0.2	0.8
Mean time between licks in bursts	1.6	2.3	4.7	1.4	0.2	-2.0	-1.2	2.2	-1.2
Mean num. licks in bursts	0.8	0.9	2.2	1.2	1.5	-0.2	-1.3	0.4	0.1
Std. dev. time between licks in bursts	1.5	1.8	3.3	0.7	0.9	-1.4	-1.3	1.6	-1.8
Water consumed over 24 hours	0.4	0.5	0.8	0.1	0.7	0.8	-0.4	-0.9	0.7
Indifference point 0 sec	0.2	0.3	1.3	-0.1	1.2	0.2	-0.7	-0.3	-0.2
Indifference point AUC	0.5	0.6	2.3	-0.3	-1.5	-0.2	0.8	0.6	0.1
Indifference point function ln k	0.7	1.0	2.8	-0.5	0.6	1.4	0.1	-1.7	0.8
Indifference point function log k	0.7	1.0	2.8	-0.5	0.6	1.4	0.1	-1.7	0.8
Delay discounting total patch changes 0 sec	0.2	0.3	0.6	-0.3	0.8	0.7	-0.3	-0.7	0.3
Delay discounting total patch changes 12 sec	0.2	0.2	0.4	0.7	0.2	0.1	-0.6	0.2	0.6
Delay discounting total patch changes 18 sec	0.3	0.4	1.3	-0.5	-1.1	0.1	0.8	0.2	0.2
Delay discounting total patch changes 24 sec	0.2	0.2	1.1	-0.2	0.2	0.1	0.2	0.0	1.0
Delay discounting total patch changes 6 sec	0.0	0.0	0.1	0.1	-0.3	-0.2	-0.1	0.2	-0.1
Delay discounting time to switch 0 sec	0.2	0.3	0.9	0.2	0.2	-0.9	-0.3	0.7	-0.4
Delay discounting water rate 0 sec	0.7	1.2	2.4	-0.4	-0.1	1.5	0.5	-1.5	1.4
Delay discounting water rate 12 sec	1.0	1.5	4.5	0.2	0.3	1.5	0.4	-1.3	2.1
Delay discounting water rate 18 sec	3.9	5.2	11.3	-0.9	-0.4	2.9	1.3	-3.0	3.4
Delay discounting water rate 24 sec	0.6	0.8	1.5	-0.4	-0.2	1.2	0.6	-1.2	1.2
Delay discounting water rate 6 sec	1.1	1.6	4.2	-0.5	-0.1	1.5	0.8	-1.3	2.1
Locomotor activity	1.8	2.9	6.7	0.3	1.5	2.0	-0.3	-2.1	2.6
Locomotor testing distance	1.1	1.8	5.2	1.4	2.3	0.2	-1.6	-0.3	1.0
Locomotor testing rearing	4.3	6.8	15.0	3.4	3.9	-1.1	-3.4	1.2	0.2
Light reinforcement 1	0.3	0.5	1.1	0.6	0.7	0.6	-0.5	-0.5	1.0
Light reinforcement 2	0.7	1.0	2.2	-1.5	-1.2	-0.2	1.2	-0.1	-0.8
Reaction time number correct	0.4	0.6	1.1	1.0	0.8	-0.6	-0.9	0.8	-0.2
Reaction time mean minus median	0.4	0.5	1.4	1.2	0.6	-0.3	-0.9	0.2	0.1
Reaction time mean minus median AUC	0.4	0.5	1.8	1.3	0.5	-0.4	-1.0	0.3	-0.1
Reaction time num false alarms	0.9	1.2	3.3	1.2	1.8	0.6	-1.3	-0.5	0.6
Reaction time num false alarms AUC	0.7	0.9	1.7	1.1	1.3	0.7	-1.0	-0.7	0.9
Reaction time trials correct on left	0.4	0.6	1.1	1.0	0.8	-0.6	-0.9	0.8	-0.2
Reaction time trials on left	0.5	0.7	1.3	1.1	0.8	-0.7	-1.0	0.9	-0.2
Reaction time mean	0.6	0.8	1.7	0.8	0.6	-1.3	-0.8	0.9	-0.9
Reaction time mean AUC	0.6	0.7	1.4	0.8	0.6	-1.2	-0.8	0.8	-1.0
Median of all reaction times	0.7	0.9	2.1	0.6	0.5	-1.5	-0.7	1.1	-1.1
Reaction time omissions	2.8	3.8	5.8	2.1	0.9	-2.4	-1.9	2.3	-1.5
Reaction time false alarm rate	0.5	0.7	1.4	0.1	0.6	1.1	-0.1	-1.2	1.0
Reaction time premature initiation rate	0.1	0.1	0.5	0.4	0.3	0.1	-0.0	-0.2	0.7
Reaction time premature initiations	0.2	0.3	0.7	0.9	0.6	-0.2	-0.5	0.3	0.4
Std. dev. reaction times	0.4	0.6	1.0	0.8	0.5	-1.0	-0.7	0.7	-0.7
Reaction time trials completed	0.5	0.7	1.3	1.1	0.8	-0.7	-1.0	0.9	-0.2
Reaction time trials AUC	0.6	0.9	1.5	1.2	0.9	-0.7	-1.1	1.0	-0.3
Social response proportion	2.2	2.4	4.7	0.9	0.4	-2.2	-1.4	1.9	-1.8
Social responses	1.5	2.0	2.9	1.1	0.7	-1.5	-1.4	1.7	-1.7
Social time	2.9	3.8	8.5	2.9	2.4	-0.7	-2.6	0.6	1.2
Conditioned locomotion	0.8	1.0	3.3	-1.8	-1.2	0.0	1.0	-0.4	-0.4
Cocaine response after cond. corrected	3.7	4.1	9.0	-2.7	-3.0	0.3	2.8	-0.5	-0.5
Cocaine response after cond. not corrected	2.9	3.3	7.2	-2.4	-2.7	0.2	2.5	-0.5	-0.4
Cocaine response before conditioning	0.9	1.1	2.5	1.5	1.6	0.1	-1.2	-0.0	0.7
Saline control response	0.5	0.6	1.0	1.0	0.4	-0.7	-0.8	1.0	-0.7
Condit. Reinf. active minus inactive responses	0.1	0.1	0.2	0.5	-0.2	-0.2	0.1	0.2	0.1
Condit. Reinf. active-inactive response ratio	0.2	0.2	1.0	1.0	0.3	0.0	-0.4	0.0	0.5
Condit. Reinf. active responses	0.1	0.1	0.3	0.4	-0.2	-0.0	0.4	0.0	0.5
Condit. Reinf. inactive responses	0.2	0.3	0.6	-0.2	-0.2	-0.7	0.3	0.7	-0.8
Condit. Reinf. lever presses	2.0	2.8	6.2	2.5	2.1	0.4	-1.5	-0.1	1.9
Condit. Reinf. lever reinforcers received	0.1	0.2	0.5	0.6	0.0	0.2	0.3	-0.1	0.7
Pavlov. Cond. lever latency	1.7	2.3	5.1	-1.8	-1.6	-1.0	1.0	0.9	-2.3
Pavlov. Cond. magazine entry latency	1.0	1.1	2.7	-0.3	0.0	1.7	0.6	-1.5	1.1
Pavlov. Cond. change in total contacts	1.3	1.9	6.0	0.9	0.8	1.4	-0.1	-1.3	2.5
Pavlov. Cond. index score	1.3	1.7	4.4	0.8	0.8	1.6	-0.0	-1.4	2.1
Pavlov. Cond. latency score	1.2	1.6	3.9	0.9	0.9	1.5	-0.2	-1.3	2.0
Pavlov. Cond. lever contacts	1.8	2.5	4.9	2.0	1.9	0.7	-1.3	-0.6	2.2
Pavlov. Cond. magazine entry number	0.8	1.0	1.9	0.1	0.1	-1.4	-0.7	1.2	-1.4
Pavlov. Cond. intertrial magazine entries	4.6	5.9	8.7	2.3	2.1	-2.8	-2.4	3.0	-1.8
Pavlov. Cond. lever-magazine prob. diff.	1.2	1.5	3.7	0.6	0.5	1.6	0.2	-1.5	1.9
Pavlov. Cond. response bias	1.4	1.9	5.2	1.2	1.2	1.3	-0.5	-1.2	2.3
Conditioned reinforcement - actives	4.3	4.2	12.1	-0.4	-0.8	-2.7	-0.4	2.3	-3.5
Conditioned reinforcement - inactives	3.3	3.8	6.6	1.5	0.9	-2.6	-2.0	2.3	-2.0
Conditioned locomotion	3.1	3.7	7.3	-2.0	-2.7	-1.7	1.5	0.9	-2.3
Intermittent access intake day 1-15 change	2.0	1.9	2.6	1.3	1.3	-1.6	-1.6	1.4	-1.1
Intermittent access intake escalation	1.6	1.6	2.3	1.0	0.9	-1.5	-1.3	1.4	-1.4
Intermittent access intake escalation 2	1.2	1.2	1.8	1.0	1.0	-1.2	-1.0	1.3	-0.9
Intermitt. access day 1 inactive lever presses	2.0	2.1	5.2	0.4	0.7	-1.7	-1.2	1.7	-2.3
Intermitt. access day 15 inactive lever presses	1.2	1.4	2.6	1.0	0.9	-1.3	-1.6	0.9	-1.2
Intermitt. access escalation Index	0.1	0.1	0.2	0.3	-0.3	-0.1	0.2	0.5	0.4
Intermittent access day 1 total infusions	1.0	1.1	3.0	-1.4	-1.7	-0.5	1.1	0.2	-0.4
Intermittent access day 15 total infusions	1.5	1.6	3.8	-0.1	-0.5	-1.9	-0.3	1.6	-1.7
Intermittent access terminal intake (last 3 days)	1.2	1.3	3.3	-0.4	-0.3	-1.8	-0.1	1.5	-1.4
Intermittent access total infusions	1.7	1.9	3.4	-1.6	-1.5	-1.3	0.8	0.9	-1.8
Intermittent access day 1 locomotion	1.2	1.2	3.0	-1.7	-1.5	0.2	1.3	-0.6	-0.1
Intermittent access day 15 total locomotion	1.0	1.1	2.4	-0.9	-1.0	-1.2	0.3	0.9	-1.5
Intermittent access total locomotion	0.9	1.0	2.1	-1.5	-1.2	-0.7	0.7	0.1	-1.3
Intermittent access standard deviation	1.1	1.2	1.8	0.7	0.9	-1.4	-1.3	1.2	-0.8
Cocaine induced anxiety	0.2	0.2	0.3	0.1	0.5	0.6	-0.1	-0.5	0.6
Post-drug Anxiety	1.6	1.8	4.0	1.7	2.0	-0.1	-1.9	-0.0	0.2
Baseline Anxiety	0.7	0.7	1.8	1.2	0.8	-0.6	-1.3	0.4	-0.2
Lifetime Intake	1.8	2.0	4.2	-1.7	-1.5	-1.1	1.0	0.7	-2.0
Incentive Sensitization - Responses	5.4	5.4	7.7	2.5	1.6	-2.8	-2.3	2.7	-1.8
Incentive Sensitization - Breakpoint	6.0	6.0	7.9	2.8	1.9	-2.8	-2.6	2.7	-1.7
Progressive ratio test 1 active lever presses	1.0	1.0	2.1	-1.4	-1.5	-0.3	1.3	-0.1	-0.5
Progressive ratio test 1 breakpoint	1.1	1.2	2.7	-1.6	-1.4	-0.2	1.4	-0.1	-0.4
Progressive ratio test 1 inactive lever presses	1.0	1.0	2.7	0.4	0.3	-1.7	-0.5	1.5	-0.8
Progressive ratio test 2 active lever presses	2.3	2.5	5.4	0.7	-0.1	-2.3	-0.8	2.0	-2.0
Progressive ratio test 2 breakpoint	1.9	2.1	5.0	0.9	0.2	-2.2	-1.0	1.8	-1.6
Progressive ratio test 2 inactive lever presses	1.9	2.2	3.6	1.5	0.8	-1.9	-1.3	1.9	-1.2
Total sessions with >9 infusions	1.6	1.8	6.7	-1.2	-0.6	-1.2	0.4	0.8	-2.6
Short access day 1 total inactive lever presses	0.2	0.2	0.7	0.1	-0.0	-0.8	-0.1	0.6	-0.3
Short access day 10 total inactive lever presses	0.7	0.8	1.4	1.2	0.1	-1.0	-0.9	1.2	0.1
Short access day 1 total infusions	2.0	2.1	5.6	-1.8	-1.0	-1.2	0.8	0.8	-2.4
Short access day 10 total infusions	1.6	1.8	4.6	-2.2	-1.7	0.1	1.6	-0.6	-0.3
Short access total infusions	1.8	1.9	5.2	-2.3	-1.4	-0.3	1.4	-0.1	-1.5
Short access day 1 locomotion	1.5	1.6	5.2	-2.3	-1.1	0.1	1.2	-0.4	-1.3
Short access day 10 total locomotion	0.2	0.2	0.6	-0.4	-0.6	0.2	0.4	-0.8	0.1
Short access total locomotion	0.6	0.6	1.8	-1.3	-0.6	0.2	0.8	-0.7	-0.5
Compulsive drug intake	0.2	0.2	0.4	0.5	0.0	0.5	0.1	-0.2	0.6
One hour access (0.3 mA shock)	1.3	1.6	4.1	-0.5	-1.3	-1.4	0.4	1.2	-2.0
One hour access (shock baseline)	1.8	2.1	5.7	-0.8	-1.0	-1.9	0.1	1.4	-2.4
Number of responses in last shaping day	0.6	0.6	2.4	-1.5	-0.5	-0.4	0.7	0.0	-0.7
Context. condit. distance diff. score	1.0	1.2	3.1	-1.3	-1.8	-0.2	1.5	-0.1	-0.2
Locomotion velocity, session 1	0.4	0.4	1.0	0.9	0.2	0.5	-0.4	-0.4	1.0
Locomotion distance, session 1	0.8	1.1	2.1	1.5	1.3	0.2	-1.1	-0.0	1.2
Locomotion velocity, session 2	0.4	0.4	0.9	0.0	0.4	0.7	-0.5	-0.9	0.9
Locomotion distance, session 2	1.8	2.6	6.0	1.9	2.4	-0.4	-2.3	0.5	0.6
Locomotion velocity, session 3	0.6	0.7	1.8	1.1	0.6	0.0	-0.8	-0.3	1.3
Locomotion distance, session 3	0.5	0.6	2.8	0.3	0.1	0.5	0.2	-0.6	1.7
Stereotopy head waving bouts, day 3	0.8	0.9	1.8	0.3	0.2	-1.3	-0.4	1.3	-1.2
Stereotopy head waving duration, day 3	0.1	0.1	0.2	0.5	0.2	-0.3	-0.2	0.3	0.0
Locomotion velocity, session 7	0.1	0.2	0.4	0.4	-0.0	-0.6	-0.3	0.2	0.4
Locomotion distance, session 7	0.7	0.8	2.2	-0.0	-0.3	-1.5	-0.5	1.2	-1.0
Stereotopy head waving bouts, day 7	1.0	1.1	3.0	1.0	0.5	1.2	-0.2	-1.1	1.7
Stereotopy head waving duration, day 7	1.3	1.6	5.1	0.9	0.2	1.4	0.1	-1.4	2.3
Locomotion velocity, session 8	0.4	0.4	1.4	-0.4	-0.1	0.5	0.4	-0.9	1.2
Locomotion distance, session 8	0.1	0.1	0.5	0.3	0.3	-0.1	-0.2	-0.1	0.7
Degree of sensitization distance	2.7	2.7	8.0	-0.4	-0.3	-2.1	-0.5	1.9	-2.8
Degree of sensitization stereotypy	1.4	1.5	3.5	0.5	-0.1	1.6	0.3	-1.6	1.9
Condit. Reinf. active minus inactive responses	1.8	2.0	4.6	1.9	2.1	0.6	-1.3	-0.3	1.1
Condit. Reinf. active-inactive response ratio	0.5	0.6	1.4	1.2	1.0	-0.3	-0.6	0.7	-0.1
Condit. Reinf. active responses	1.5	1.8	3.3	1.8	1.7	0.9	-1.1	-0.6	1.5
Condit. Reinf. inactive responses	0.4	0.5	1.4	0.6	0.4	0.6	-0.4	-0.7	1.2
Incentive salience index mean	2.0	2.4	3.6	1.5	1.9	1.7	-0.8	-1.4	1.7
Condit. Reinf. lever presses	1.9	2.6	5.5	0.8	1.2	2.4	-0.1	-2.2	1.8
Time in familiar zone, hab. session 1	0.5	0.4	0.9	-0.5	-0.8	0.8	0.9	-0.4	-0.0
Time in novel zone, hab. session 1	0.1	0.1	0.4	-0.6	0.3	-0.1	-0.1	-0.1	0.2
Total zone transitions, hab. session 1	0.6	0.9	1.6	-0.6	-0.4	1.3	0.7	-1.2	1.2
Total locomotion distance, hab. session 1	0.1	0.1	0.4	-0.3	-0.2	0.6	0.3	-0.3	0.2
Locomotion velocity, hab. session 1	0.1	0.1	0.4	0.3	0.2	0.6	-0.1	-0.3	0.4
Time in familiar zone, hab. session 2	0.4	0.4	0.6	-0.7	-0.8	-0.3	0.6	0.3	-0.8
Time in novel zone, hab. session 2	0.5	0.5	1.3	0.7	1.2	0.1	-0.7	-0.0	0.6
Total zone transitions, hab. session 2	0.9	1.2	3.8	0.2	0.4	1.3	-0.0	-1.3	1.9
Total locomotion distance, hab. session 2	0.8	1.1	2.8	-0.5	-0.1	1.4	0.5	-1.2	1.7
Locomotion velocity, hab. session 2	1.0	1.3	3.2	-0.4	0.0	1.5	0.5	-1.4	1.8
Novel to familiar place preference ratio	0.7	0.8	2.0	0.1	1.4	-0.6	-0.9	0.6	-1.1
Novelty place preference	1.0	1.0	3.1	0.3	1.8	-0.5	-1.2	0.5	-1.0
Time in novel zone, NPP test	1.2	1.3	3.9	0.5	2.0	-0.6	-1.4	0.6	-0.9
Total zone transitions, NPP test	0.5	0.7	1.7	0.5	0.6	1.0	-0.3	-0.9	1.3
Total locomotion distance, NPP test	0.7	1.0	2.4	1.2	1.5	-0.5	-1.3	0.7	-0.0
Locomotion velocity, NPP test	0.5	0.7	1.6	1.0	1.3	-0.4	-1.0	0.6	0.1
Pavlov. Cond. lever latency	0.9	1.1	3.0	0.1	-0.3	-1.6	-0.3	1.7	-0.9
Pavlov. Cond. magazine entry latency	0.3	0.4	1.0	0.3	0.8	1.0	-0.4	-0.8	-0.3
Pavlov. Cond. change in total contacts	1.2	1.3	3.5	-0.1	0.8	1.8	0.1	-1.9	0.5
Pavlov. Cond. index score	1.7	2.2	5.6	-0.0	0.7	2.3	0.2	-2.4	1.3
Pavlov. Cond. latency score	1.4	1.8	4.5	0.3	0.8	2.1	0.0	-2.1	1.1
Pavlov. Cond. lever contacts	1.3	1.6	4.2	0.2	0.7	1.9	0.1	-2.0	1.0
Pavlov. Cond. magazine entry number	0.8	0.9	2.3	-0.3	-1.0	-1.5	0.2	1.4	-0.6
Pavlov. Cond. intertrial magazine entries	0.4	0.4	1.3	0.6	0.5	0.7	0.0	-0.4	1.1
Pavlov. Cond. lever-magazine prob. diff.	2.0	2.5	6.4	-0.1	0.6	2.4	0.4	-2.5	1.4
Pavlov. Cond. response bias	1.6	1.9	4.8	-0.1	0.4	2.2	0.5	-2.2	1.2
Bone: apparent density	1.1	1.8	5.0	1.2	2.2	-0.8	-1.7	0.8	-0.2
Bone surface	0.7	1.3	5.1	0.6	2.3	-0.4	-1.3	0.4	-0.3
Bone volume	0.3	0.6	2.7	0.1	1.6	-0.0	-0.9	0.0	-0.1
Bone: connectivity density	2.5	3.9	6.8	2.0	2.6	-2.0	-2.3	1.8	-0.8
Bone: cortical apparent density	0.9	1.2	3.5	-0.5	-1.9	0.5	1.7	-0.2	0.4
Bone: cortical area	1.2	1.8	3.3	-1.8	-0.6	1.6	1.6	-1.4	0.1
Bone: cortical porosity	0.9	1.0	1.9	-0.2	0.4	1.3	0.3	-1.4	1.4
Bone: cortical porosity	0.7	0.8	1.6	-0.3	0.4	1.1	0.5	-1.1	1.3
Bone: cortical thickness	1.6	2.6	4.2	-1.8	-1.2	1.9	2.1	-1.7	0.4
Bone: cortical thickness	2.6	3.1	5.2	-1.9	-1.7	1.5	2.3	-1.7	1.3
Bone: cortical tissue density	0.9	1.1	3.5	-0.5	-1.9	0.4	1.6	-0.2	0.4
Bone: elastic displacement	0.4	0.5	1.0	0.4	0.4	-0.8	-0.8	1.0	-0.2
Bone: elastic work	0.3	0.4	1.2	0.6	1.1	0.4	-0.7	-0.0	0.6
Bone: endosteal estimation	0.2	0.5	1.8	0.0	1.3	-0.0	-1.0	0.2	-0.5
Bone: endosteal perimeter	0.4	0.8	2.0	-0.1	1.4	-0.6	-1.0	0.6	-1.0
Bone: final force	1.1	1.9	4.6	-1.0	-0.1	2.1	0.9	-1.9	1.1
Bone: final moment	0.8	1.4	3.8	-0.5	0.3	2.0	0.4	-1.6	1.2
Bone: marrow area	0.3	0.5	1.8	0.0	1.3	-0.1	-1.0	0.2	-0.6
Bone: maximum diameter	0.8	1.5	5.0	-2.2	-0.7	0.7	1.4	-0.7	-0.6
Bone: maximum force	1.1	1.9	4.5	-1.3	-0.1	2.1	1.0	-1.8	0.9
Bone: maximum moment	0.8	1.4	3.8	-0.7	0.4	1.9	0.5	-1.6	1.1
Bone: minimum diameter	0.3	0.6	1.2	-1.1	0.6	1.1	0.2	-0.8	-0.4
Bone: periosteal estimation	0.2	0.4	1.2	-1.1	0.4	0.6	0.2	-0.4	-0.6
Bone: periosteal perimeter	0.2	0.3	0.8	-0.9	0.5	0.4	0.2	-0.4	-0.5
Bone: post-yield work	2.1	2.9	6.1	-2.3	-1.9	0.9	2.5	-1.0	0.4
Bone: stiffness	1.1	1.8	3.5	-1.5	-0.3	1.9	1.1	-1.9	0.6
Bone: tissue strength	1.5	1.5	2.2	1.4	1.0	-1.0	-1.4	1.5	-0.8
Bone: trabecular number	1.2	1.8	4.9	0.9	2.2	-1.2	-1.5	1.0	-0.6
Bone: trabecular spacing	2.3	3.0	5.6	-2.0	-2.4	1.4	2.1	-1.2	0.4
Bone: trabecular thickness	0.7	0.8	1.5	-0.1	0.8	1.2	-0.0	-1.2	1.2
Bone: trabecular tissue density	1.5	2.1	3.0	-1.4	-1.7	1.5	1.7	-1.4	0.8
Breakpoint value in progressive ratio session	0.2	0.2	0.9	-0.4	-0.9	-0.3	0.3	0.1	0.3
Distance traveled before self-admin	0.1	0.1	0.2	0.4	0.0	-0.3	-0.4	0.2	-0.3
Distance traveled after self-admin	0.2	0.3	0.6	-0.7	-0.4	-0.6	0.2	0.0	-0.7
Delta time in closed arm before/after self-admin	0.2	0.2	0.6	-0.5	0.2	0.8	0.3	-0.4	-0.1
Delta time in open arm before/after self-admin	1.4	1.3	4.3	-0.2	-0.4	-1.5	-0.3	1.0	-2.1
Diff in mean of infusions in LGA sessions	0.3	0.3	0.8	-0.9	-0.0	0.5	0.1	-0.8	0.4
Extinction: sum of active levers before priming	0.2	0.2	0.4	-0.2	-0.6	-0.5	0.1	0.5	-0.4
Active lever presses in extinction session 6	0.8	0.8	1.3	1.1	0.4	-1.1	-1.0	1.0	0.0
Delta distance traveled before/after self-admin	0.2	0.2	0.7	-0.7	-0.0	-0.5	0.1	0.1	-0.8
Delta ambulatory time before/after self-admin	0.3	0.3	0.6	-0.7	-0.4	-0.6	0.3	0.2	-0.7
Time in closed arm before self-admin	1.3	1.5	3.8	-0.5	-0.3	1.1	0.9	-1.9	1.7
Time in closed arm after self-admin	3.5	3.6	7.7	-1.1	-0.1	2.6	1.4	-2.8	2.0
Time in open arm before self-admin	1.2	1.3	2.4	1.6	1.5	-0.2	-1.4	0.9	0.5
Time in open arm after self-admin	2.3	2.5	4.1	1.2	0.7	-2.0	-1.5	2.0	-1.6
Sum of active levers in priming session hrs 5-6	0.5	0.5	1.2	0.7	0.0	-1.1	-0.4	1.1	-0.1
Time to tail flick, vehicle, before self-admin	0.6	0.6	1.5	1.2	0.9	0.0	-1.1	-0.1	0.0
Time to tail flick, vehicle, after self-admin	0.1	0.1	0.7	0.1	-0.1	0.1	-0.1	-0.2	0.8
Time to tail flick, test, before self-admin	1.6	1.6	5.0	2.2	0.9	-0.5	-1.5	0.5	1.0
Time to tail flick, test, after self-admin	2.5	2.6	4.3	1.5	1.2	-1.6	-1.6	2.1	-1.6
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.2	-0.4	-0.1	-0.2	0.2	0.2	0.4
Delta time to tail flick, test, before/after SA	1.0	0.9	2.7	-0.1	0.4	-1.0	-0.2	1.3	-1.6
Ambulatory time before self-admin	0.2	0.2	0.4	-0.0	-0.3	0.6	0.3	-0.6	0.6
Ambulatory time after self-admin	0.7	0.7	1.7	-1.3	-0.7	0.5	1.0	-0.9	0.4
Total heroin consumption	0.0	0.1	0.2	-0.1	-0.5	0.1	0.2	-0.1	0.1
Area under the delay curve	5.6	6.0	8.9	-2.4	-2.0	2.6	2.6	-3.0	2.0
Delay disc. indifference point, 0s delay	0.5	0.5	0.8	-0.8	-0.9	0.5	0.7	-0.8	0.4
Delay disc. indifference point, 16s delay	3.9	3.9	6.5	-2.5	-2.3	1.2	2.5	-1.8	0.9
Delay disc. indifference point, 2s delay	1.2	1.3	3.2	-0.3	-0.5	1.8	0.8	-1.4	1.3
Delay disc. indifference point, 24s delay	2.8	2.7	4.0	-1.9	-1.7	1.4	2.0	-1.8	0.8
Delay disc. indifference point, 4s delay	4.3	4.5	7.8	-1.6	-1.0	2.6	1.9	-2.8	2.3
Delay disc. indifference point, 8s delay	6.5	6.7	10.3	-2.8	-1.8	2.8	2.7	-3.2	1.8
Delay discount exponential model param	6.3	6.7	10.3	2.3	1.9	-2.9	-2.7	3.2	-2.3
Delay discount hyperbolic model param	6.0	6.4	9.9	2.2	1.8	-2.9	-2.6	3.1	-2.3
Fecal boli incidents, locomotor time 1	0.9	1.0	1.8	-0.2	-0.5	1.2	1.1	-1.1	1.4
Change in fecal boli incidents, locomotor task	0.5	0.5	1.2	0.2	1.1	-0.7	-1.1	0.3	-0.5
Time >=10cm from walls, locomotor time 1	2.0	2.0	4.1	2.0	1.8	-0.4	-2.0	0.6	-0.1
Bouts of movement, locomotor time 1	0.5	0.6	1.5	0.1	-0.1	0.9	-0.0	-1.2	1.1
Total resting periods, locomotor time 1	0.5	0.6	1.2	-0.2	-0.6	0.8	0.4	-1.1	1.0
Rest time, locomotor task time 1	1.4	1.5	3.6	-0.1	-0.6	1.5	1.0	-1.4	1.9
Distance moved, locomotor task time 1	1.1	1.2	2.5	0.2	0.3	-1.4	-0.8	1.4	-1.6
Vertical activity count, locomotor time 1	0.6	0.7	1.4	-0.1	0.2	-1.1	-0.6	1.2	-1.0
Time >=10cm from walls, locomotor time 2	0.9	0.9	2.5	1.2	1.2	-0.2	-1.6	0.2	-0.3
Bouts of movement, locomotor time 2	2.6	2.8	4.5	-2.1	-1.4	1.7	1.6	-2.1	0.6
Total resting periods, locomotor time 2	2.8	3.0	5.1	-1.9	-1.3	1.9	1.6	-2.3	0.9
Rest time, locomotor task time 2	1.5	1.8	3.5	-0.7	-0.5	1.7	1.1	-1.6	1.9
Distance moved, locomotor task time 2	0.6	0.7	1.3	0.5	0.0	-1.1	-0.8	1.2	-0.8
Vertical activity count, locomotor time 2	0.5	0.5	1.1	-0.5	-0.6	-0.7	0.2	0.9	-1.0
Weight adjusted by age	1.1	1.2	2.1	1.0	1.4	0.9	-0.7	-1.1	1.3
Seeking ratio, delayed vs. immediate footshock	0.9	1.0	2.7	-1.7	-1.1	0.2	0.8	-0.9	-1.0
Locomotion in novel chamber	0.5	0.6	2.4	0.3	0.3	0.6	0.3	-0.9	1.6
Locomotion in novel chamber post-restriction	0.4	0.4	1.0	-0.9	0.3	0.5	0.2	-1.0	0.7
Progressive ratio	0.1	0.1	0.5	0.1	-0.1	-0.5	-0.0	0.0	0.7
Food seeking constrained by brief footshock	0.9	1.1	4.0	-1.0	-2.0	-0.1	1.1	0.5	-0.4
Seeking ratio, punishment vs. effort	0.4	0.5	1.1	-0.8	-1.0	0.9	0.8	-0.3	-0.3
Run reversals in cocaine runway, females	0.9	0.9	1.3	0.7	0.7	-1.0	-0.9	1.0	-1.1
Run reversals in cocaine runway, males	1.0	0.9	2.1	-0.8	-0.4	1.4	0.8	-1.3	0.6
Latency to leave start box in cocaine runway	0.3	0.4	0.6	0.2	0.6	-0.7	-0.5	0.7	-0.8
Latency to leave start box in cocaine runway, F	0.5	0.6	1.9	0.1	0.6	-0.7	-0.6	0.7	-1.4
Latency to leave start box in cocaine runway, M	0.6	0.6	1.3	1.1	0.8	-0.5	-0.7	0.9	0.4
Cd content in liver	0.7	0.8	1.3	0.8	1.1	-0.8	-0.9	0.8	-0.9
Co content in liver	2.4	2.9	4.5	-2.1	-1.4	1.7	2.1	-1.8	0.6
Cu content in liver	0.9	1.0	2.2	0.8	1.5	0.7	-0.5	-0.7	1.4
Fe content in liver	0.9	1.0	1.6	1.3	0.8	-1.2	-1.0	1.1	-0.5
K content in liver	0.8	0.8	1.9	-1.2	-1.2	-0.2	1.4	0.2	-0.3
Mg content in liver	0.7	0.7	1.2	-0.9	-0.6	-0.7	0.7	0.8	-1.1
Mn content in liver	0.6	0.7	1.6	-0.8	-1.0	-0.4	0.5	0.6	-1.3
Na content in liver	1.4	1.5	2.6	0.5	1.3	1.5	-0.4	-1.4	1.6
Rb content in liver	1.5	1.9	4.9	0.1	0.2	-1.8	-0.7	1.7	-2.2
Se content in liver	0.5	0.6	2.6	-0.6	0.5	-0.5	-0.5	0.5	-1.6
Sr content in liver	3.0	2.8	3.7	1.9	1.5	-1.8	-1.9	1.9	-0.7
Zn content in liver	1.1	1.2	2.1	-0.2	1.4	1.5	-0.0	-1.3	1.1