Hub : Genes

Rara

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability ENSRNOG00000009972 0.05 0.04 3.7e-05 0.06 0.06 0.06 0.06 5.9e-06 5.5e-06 6.8e-06 4.5e-06
2 Liver gene expression ENSRNOG00000009972 0.04 0.03 3.1e-04 0.03 0.02 0.02 0.02 3.3e-04 2.0e-03 2.2e-03 1.9e-03
3 Liver intron excision ratio chr10:83893592:83902691 0.03 0.02 3.0e-03 0.02 0.01 0.01 0.01 1.0e-03 9.5e-03 5.4e-02 1.9e-02
4 Liver intron excision ratio chr10:83893592:83905392 0.06 0.04 1.7e-05 0.05 0.04 0.03 0.05 3.5e-06 1.5e-05 2.4e-04 2.2e-06
5 Liver mRNA stability ENSRNOG00000009972 0.09 0.06 4.2e-06 0.05 0.06 0.03 0.04 6.6e-06 9.8e-07 2.1e-04 1.3e-05
6 NAcc gene expression ENSRNOG00000009972 0.04 0.03 9.1e-03 0.02 0.01 0.01 0.01 1.1e-02 5.0e-02 4.6e-02 7.9e-02
7 OFC gene expression ENSRNOG00000009972 0.15 0.1 4.6e-03 0.08 0.04 0.08 0.07 5.4e-03 3.7e-02 5.0e-03 7.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail2.27.19.93.1-2.7-2.22.63.0-1.9-2.8
BMI without tail0.10.30.90.9-0.4-0.10.40.4-0.6-0.6
Body weight4.519.125.34.7-4.4-4.24.55.0-2.9-4.6
Epididymis fat weight0.00.10.1-0.1-0.1-0.40.30.1-0.3-0.1
Glucose0.00.00.30.1-0.10.10.0-0.00.50.1
Heart weight3.95.56.92.2-2.6-2.32.32.2-2.2-2.6
Left kidney weight0.72.14.51.1-1.6-1.21.62.10.1-1.7
Right kidney weight0.20.61.50.6-0.5-0.50.41.21.1-0.5
Tail length0.10.40.70.5-0.4-0.90.70.7-0.4-0.5
Length with tail2.17.510.62.4-2.7-3.13.03.3-1.5-2.9
Length without tail2.96.39.72.3-2.6-2.82.73.1-0.9-2.6
Liver weight, left0.10.10.2-0.30.4-0.2-0.1-0.20.50.3
Liver weight, right0.91.56.2-1.00.90.9-0.9-0.22.50.9
Parametrial fat weight2.14.14.8-1.82.12.1-2.1-1.82.22.1
Retroperitoneal fat weight0.00.10.30.3-0.50.30.20.50.3-0.4
Intraocular pressure3.44.88.52.4-2.0-1.92.11.8-2.9-2.0
Extensor digitorum longus weight9.136.639.66.1-6.1-6.36.36.1-5.1-6.3
Soleus weight0.00.10.30.6-0.1-0.10.10.40.3-0.2
Tibialis anterior weight1.45.07.32.5-2.2-2.22.32.7-0.9-2.3
Tibia length1.64.67.22.4-2.2-2.12.12.7-0.8-2.2
Number of licking bursts0.20.20.4-0.40.60.3-0.3-0.50.40.6
Food consumed during 24 hour testing period0.81.01.21.1-1.0-0.71.11.0-1.0-1.0
Times rat made contact with spout0.80.91.7-0.91.01.3-1.0-1.2-0.10.9
Mean time between licks in bursts1.11.63.71.3-1.2-0.91.10.8-1.9-1.3
Mean num. licks in bursts0.10.10.4-0.30.10.7-0.4-0.3-0.40.1
Std. dev. time between licks in bursts0.00.00.00.2-0.0-0.1-0.1-0.0-0.1-0.1
Water consumed over 24 hours0.20.20.50.4-0.4-0.10.50.1-0.7-0.4
Indifference point 0 sec1.83.05.0-2.01.61.7-1.8-2.20.41.6
Indifference point AUC0.10.10.20.3-0.2-0.50.20.20.40.1
Indifference point function ln k0.00.00.1-0.2-0.1-0.00.20.0-0.2-0.3
Indifference point function log k0.00.00.1-0.2-0.1-0.00.20.0-0.2-0.3
Delay discounting total patch changes 0 sec1.32.13.9-1.71.31.4-1.5-2.00.21.4
Delay discounting total patch changes 12 sec5.27.08.9-2.62.62.4-2.8-3.02.03.0
Delay discounting total patch changes 18 sec0.60.81.4-0.90.90.7-0.9-1.20.51.0
Delay discounting total patch changes 24 sec1.51.92.6-1.51.30.7-1.4-1.31.61.5
Delay discounting total patch changes 6 sec2.13.24.3-1.91.61.9-1.9-2.11.01.8
Delay discounting time to switch 0 sec0.10.20.3-0.40.40.3-0.5-0.30.10.5
Delay discounting water rate 0 sec0.10.10.1-0.40.30.4-0.3-0.40.10.2
Delay discounting water rate 12 sec0.10.10.4-0.20.2-0.60.50.10.3-0.1
Delay discounting water rate 18 sec0.70.92.7-0.91.00.7-0.6-0.71.60.8
Delay discounting water rate 24 sec0.60.91.6-0.80.91.3-0.9-1.10.70.8
Delay discounting water rate 6 sec1.82.73.0-1.61.71.6-1.4-1.61.71.7
Locomotor activity0.71.01.7-1.01.20.7-0.9-0.91.31.2
Locomotor testing distance2.44.04.8-2.22.11.9-1.9-2.01.52.2
Locomotor testing rearing6.39.911.9-3.23.23.4-3.1-3.22.43.3
Light reinforcement 13.46.27.5-2.52.42.5-2.7-2.52.12.6
Light reinforcement 20.50.71.2-0.40.61.1-1.1-0.50.90.8
Reaction time number correct0.71.01.60.8-1.0-1.31.10.9-0.6-1.0
Reaction time mean minus median0.50.62.40.5-0.5-0.90.40.3-1.5-0.6
Reaction time mean minus median AUC0.10.21.00.1-0.1-0.2-0.1-0.1-1.0-0.1
Reaction time num false alarms0.40.61.0-0.40.70.9-1.0-0.80.70.8
Reaction time num false alarms AUC0.40.50.9-0.40.70.7-0.9-0.90.40.7
Reaction time trials correct on left0.71.01.60.8-1.0-1.31.10.9-0.6-1.0
Reaction time trials on left0.60.91.60.7-1.0-1.31.10.8-0.6-1.0
Reaction time mean0.20.30.6-0.60.70.4-0.8-0.60.20.5
Reaction time mean AUC0.20.30.6-0.60.70.3-0.8-0.50.40.5
Median of all reaction times1.11.52.1-1.21.41.2-1.5-1.21.01.2
Reaction time omissions1.11.52.2-1.31.21.2-1.5-1.30.81.3
Reaction time false alarm rate0.81.21.7-0.81.11.3-1.3-1.10.81.1
Reaction time premature initiation rate1.01.35.7-0.91.00.3-0.7-0.22.41.0
Reaction time premature initiations0.30.52.6-0.20.1-0.60.10.51.60.2
Std. dev. reaction times0.10.10.5-0.10.1-0.3-0.2-0.2-0.70.0
Reaction time trials completed0.60.91.60.7-1.0-1.31.10.8-0.6-1.0
Reaction time trials AUC0.60.91.60.7-1.0-1.31.10.7-0.7-0.9
Social response proportion0.50.50.80.6-0.9-0.70.70.9-0.2-0.8
Social responses0.00.00.20.10.00.4-0.10.00.20.1
Social time0.10.10.40.5-0.1-0.20.00.2-0.6-0.0
Conditioned locomotion0.20.20.5-0.50.50.2-0.4-0.30.70.5
Cocaine response after cond. corrected0.60.71.7-0.50.90.7-0.9-0.41.30.9
Cocaine response after cond. not corrected0.80.92.3-0.61.00.7-0.9-0.51.51.0
Cocaine response before conditioning0.10.10.2-0.40.10.1-0.2-0.40.30.2
Saline control response0.20.30.50.6-0.5-0.60.60.70.2-0.4
Condit. Reinf. active minus inactive responses1.21.52.1-1.11.31.2-1.4-1.40.71.4
Condit. Reinf. active-inactive response ratio1.11.11.7-0.81.11.2-1.3-1.20.51.2
Condit. Reinf. active responses2.02.83.5-1.51.81.7-1.8-1.81.11.9
Condit. Reinf. inactive responses2.02.53.0-1.51.71.6-1.6-1.61.31.7
Condit. Reinf. lever presses0.20.30.4-0.60.50.5-0.5-0.50.50.5
Condit. Reinf. lever reinforcers received2.12.93.5-1.61.81.7-1.8-1.81.21.9
Pavlov. Cond. lever latency0.40.60.70.8-0.8-0.80.80.8-0.3-0.8
Pavlov. Cond. magazine entry latency0.10.10.20.3-0.2-0.50.20.2-0.3-0.2
Pavlov. Cond. change in total contacts0.70.91.8-1.00.91.0-0.9-1.30.11.0
Pavlov. Cond. index score0.20.20.3-0.40.40.5-0.5-0.5-0.00.5
Pavlov. Cond. latency score0.10.10.2-0.20.30.3-0.4-0.4-0.20.3
Pavlov. Cond. lever contacts0.81.11.3-1.01.11.2-1.1-1.10.71.1
Pavlov. Cond. magazine entry number0.00.00.00.1-0.1-0.00.20.1-0.1-0.1
Pavlov. Cond. intertrial magazine entries1.31.72.21.0-1.3-1.51.51.1-1.3-1.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.20.30.4-0.4-0.4-0.10.3
Pavlov. Cond. response bias1.11.61.8-1.21.31.3-1.3-1.30.91.3
Conditioned reinforcement - actives0.70.71.3-1.01.10.3-0.4-1.1-0.31.0
Conditioned reinforcement - inactives2.12.43.9-1.61.61.7-1.7-2.0-0.11.4
Conditioned locomotion0.40.51.1-0.71.00.1-0.5-1.1-0.40.8
Intermittent access intake day 1-15 change0.80.81.2-0.91.10.7-0.9-0.71.10.8
Intermittent access intake escalation0.80.81.6-0.91.10.6-0.9-0.71.30.8
Intermittent access intake escalation 20.10.10.1-0.10.30.2-0.2-0.10.40.1
Intermitt. access day 1 inactive lever presses2.93.15.3-1.61.62.0-2.0-1.22.31.5
Intermitt. access day 15 inactive lever presses4.85.36.3-2.52.42.4-2.5-2.31.62.3
Intermitt. access escalation Index2.11.93.41.4-1.5-1.21.41.90.2-1.4
Intermittent access day 1 total infusions0.20.20.3-0.50.40.4-0.4-0.50.20.5
Intermittent access day 15 total infusions0.91.02.1-1.01.00.8-1.0-0.71.50.9
Intermittent access terminal intake (last 3 days)1.01.01.3-1.01.11.0-1.1-0.81.21.0
Intermittent access total infusions0.30.40.8-0.60.60.5-0.6-0.40.90.5
Intermittent access day 1 locomotion0.30.30.6-0.50.50.4-0.4-0.8-0.50.5
Intermittent access day 15 total locomotion0.60.61.7-0.40.60.4-0.7-1.0-1.30.5
Intermittent access total locomotion0.91.01.6-1.11.10.8-1.0-1.3-0.31.0
Intermittent access standard deviation2.83.03.7-1.81.91.5-1.9-1.71.41.8
Cocaine induced anxiety1.82.14.21.7-1.5-1.21.32.1-0.1-1.5
Post-drug Anxiety0.30.30.80.6-0.5-0.30.50.90.5-0.5
Baseline Anxiety1.21.32.4-1.41.10.9-1.0-1.60.11.2
Lifetime Intake0.50.61.5-0.80.80.6-0.7-0.41.20.6
Incentive Sensitization - Responses1.81.83.3-1.31.31.5-1.1-1.8-0.91.2
Incentive Sensitization - Breakpoint1.71.73.1-1.31.31.5-1.1-1.8-0.91.2
Progressive ratio test 1 active lever presses0.60.71.2-0.80.71.1-0.7-0.60.90.7
Progressive ratio test 1 breakpoint0.50.61.0-0.70.71.0-0.7-0.50.90.6
Progressive ratio test 1 inactive lever presses2.32.43.6-1.61.41.9-1.7-1.21.71.3
Progressive ratio test 2 active lever presses1.51.62.2-1.41.41.5-1.1-1.50.31.2
Progressive ratio test 2 breakpoint1.11.21.8-1.21.21.3-0.9-1.20.31.1
Progressive ratio test 2 inactive lever presses0.70.81.0-1.00.91.0-1.0-1.00.10.8
Total sessions with >9 infusions0.91.01.8-1.00.91.0-1.0-0.71.30.8
Short access day 1 total inactive lever presses2.32.63.9-1.71.51.6-2.0-1.61.21.6
Short access day 10 total inactive lever presses0.10.10.50.1-0.1-0.2-0.20.40.7-0.2
Short access day 1 total infusions1.31.43.7-1.11.01.3-1.0-0.51.90.9
Short access day 10 total infusions0.40.50.6-0.70.70.6-0.7-0.60.80.7
Short access total infusions0.80.93.2-0.90.80.8-0.8-0.31.80.7
Short access day 1 locomotion4.44.66.0-2.22.22.4-2.5-2.11.62.1
Short access day 10 total locomotion1.41.52.6-1.11.31.4-1.2-1.6-0.61.3
Short access total locomotion0.60.60.9-0.80.80.9-0.9-1.0-0.10.7
Compulsive drug intake0.40.41.10.4-0.6-0.50.60.2-1.1-0.6
One hour access (0.3 mA shock)0.00.00.1-0.20.2-0.20.1-0.10.10.2
One hour access (shock baseline)0.40.40.9-0.50.70.4-0.6-0.41.00.7
Number of responses in last shaping day0.80.81.1-1.00.90.8-1.0-0.71.00.8
Context. condit. distance diff. score1.62.03.01.2-1.7-1.31.51.4-1.0-1.6
Locomotion velocity, session 10.40.50.80.9-0.6-0.80.60.8-0.1-0.6
Locomotion distance, session 12.02.63.51.9-1.6-1.81.51.8-0.9-1.5
Locomotion velocity, session 20.10.10.20.3-0.3-0.50.30.40.3-0.3
Locomotion distance, session 20.10.10.30.3-0.0-0.50.10.40.2-0.0
Locomotion velocity, session 30.10.10.3-0.50.20.1-0.3-0.30.30.3
Locomotion distance, session 30.10.10.30.2-0.4-0.60.30.3-0.4-0.3
Stereotopy head waving bouts, day 32.32.73.4-1.71.61.9-1.7-1.51.81.5
Stereotopy head waving duration, day 30.20.21.0-0.10.10.6-0.3-0.01.00.1
Locomotion velocity, session 71.11.22.11.2-1.0-1.41.21.0-0.8-0.9
Locomotion distance, session 70.60.81.90.8-0.8-1.10.90.4-1.4-0.7
Stereotopy head waving bouts, day 70.60.71.7-0.70.70.8-0.9-0.41.30.7
Stereotopy head waving duration, day 70.50.62.2-0.70.60.6-0.7-0.11.50.6
Locomotion velocity, session 87.79.310.43.1-3.2-3.13.23.2-2.2-3.1
Locomotion distance, session 81.31.92.41.4-1.5-1.51.41.6-0.7-1.4
Degree of sensitization distance1.61.72.41.4-1.3-1.21.30.9-1.5-1.2
Degree of sensitization stereotypy0.80.91.6-0.90.90.9-1.1-0.61.31.0
Condit. Reinf. active minus inactive responses1.01.11.6-1.31.10.7-1.1-1.10.71.1
Condit. Reinf. active-inactive response ratio1.11.22.0-1.41.10.8-1.1-1.20.91.1
Condit. Reinf. active responses0.91.11.5-1.21.10.7-1.1-1.20.71.1
Condit. Reinf. inactive responses0.10.10.2-0.20.40.1-0.3-0.30.40.4
Incentive salience index mean2.02.43.1-1.71.61.4-1.6-1.80.91.6
Condit. Reinf. lever presses0.91.22.0-1.11.11.0-1.1-1.40.51.2
Time in familiar zone, hab. session 10.30.31.20.20.30.8-0.3-0.01.10.3
Time in novel zone, hab. session 10.70.71.4-1.10.60.5-0.8-1.2-0.70.6
Total zone transitions, hab. session 11.92.63.01.7-1.7-1.51.61.6-1.4-1.6
Total locomotion distance, hab. session 10.00.00.10.1-0.3-0.10.10.10.0-0.2
Locomotion velocity, hab. session 10.20.30.60.6-0.6-0.60.50.80.0-0.6
Time in familiar zone, hab. session 20.70.72.3-0.50.70.9-0.8-0.21.50.7
Time in novel zone, hab. session 20.30.30.8-0.70.50.3-0.4-0.9-0.50.5
Total zone transitions, hab. session 21.21.62.11.4-1.3-1.31.21.1-1.4-1.2
Total locomotion distance, hab. session 20.30.40.80.8-0.6-0.60.30.5-0.9-0.6
Locomotion velocity, hab. session 20.50.70.91.0-0.8-0.90.60.8-0.9-0.8
Novel to familiar place preference ratio0.80.81.40.6-0.8-1.11.11.2-0.1-0.9
Novelty place preference0.70.71.10.5-0.7-1.01.11.0-0.2-0.8
Time in novel zone, NPP test0.20.20.40.1-0.3-0.60.70.60.1-0.5
Total zone transitions, NPP test0.81.12.21.5-1.1-0.80.90.9-1.1-0.9
Total locomotion distance, NPP test0.10.10.40.6-0.4-0.0-0.10.1-0.6-0.3
Locomotion velocity, NPP test0.50.81.31.2-1.0-0.60.50.6-1.1-0.9
Pavlov. Cond. lever latency2.63.34.01.6-1.9-2.01.81.8-1.4-2.0
Pavlov. Cond. magazine entry latency9.712.514.0-3.53.63.7-3.7-3.53.03.6
Pavlov. Cond. change in total contacts8.69.111.4-3.22.93.4-3.0-3.22.33.0
Pavlov. Cond. index score7.59.511.2-3.03.23.3-3.2-3.22.33.3
Pavlov. Cond. latency score5.57.18.5-2.52.72.9-2.8-2.72.12.8
Pavlov. Cond. lever contacts2.12.43.2-1.41.71.8-1.6-1.70.91.7
Pavlov. Cond. magazine entry number11.414.317.33.8-3.8-4.24.03.9-2.9-3.9
Pavlov. Cond. intertrial magazine entries1.41.72.61.1-1.3-1.61.41.2-1.1-1.3
Pavlov. Cond. lever-magazine prob. diff.8.310.412.2-3.23.33.5-3.4-3.42.33.4
Pavlov. Cond. response bias8.710.612.4-3.33.23.5-3.4-3.42.63.3
Bone: apparent density2.54.15.2-1.92.02.0-2.2-1.82.32.0
Bone surface0.10.21.00.00.10.3-0.30.11.00.1
Bone volume0.20.41.3-0.20.40.7-0.7-0.31.10.4
Bone: connectivity density3.65.76.8-2.42.32.2-2.6-2.22.62.4
Bone: cortical apparent density5.26.810.2-2.92.62.6-2.8-3.21.22.6
Bone: cortical area0.00.10.1-0.40.20.2-0.2-0.30.30.2
Bone: cortical porosity0.20.20.9-0.20.40.4-0.1-0.00.90.4
Bone: cortical porosity0.20.20.90.00.20.20.00.21.00.3
Bone: cortical thickness0.91.42.1-1.51.20.8-1.1-1.21.31.1
Bone: cortical thickness5.46.39.5-2.62.42.2-2.5-2.23.12.5
Bone: cortical tissue density5.36.810.2-2.82.62.6-2.8-3.21.12.6
Bone: elastic displacement0.10.21.00.0-0.0-0.2-0.0-0.3-1.0-0.1
Bone: elastic work0.10.20.5-0.30.30.2-0.4-0.20.70.3
Bone: endosteal estimation1.84.05.92.4-2.1-1.52.12.3-1.2-2.1
Bone: endosteal perimeter1.22.43.01.7-1.6-1.11.61.4-1.6-1.6
Bone: final force0.61.02.8-0.60.91.0-0.9-0.61.70.8
Bone: final moment0.40.62.1-0.40.70.8-0.7-0.41.40.6
Bone: marrow area1.73.75.52.4-2.0-1.42.02.2-1.2-2.0
Bone: maximum diameter0.00.10.1-0.30.30.4-0.2-0.20.30.3
Bone: maximum force0.10.10.50.4-0.20.10.20.40.7-0.3
Bone: maximum moment0.10.20.30.6-0.4-0.10.40.50.4-0.4
Bone: minimum diameter0.40.81.10.9-1.0-0.71.01.1-0.3-0.9
Bone: periosteal estimation0.20.40.70.8-0.7-0.30.70.8-0.1-0.7
Bone: periosteal perimeter0.61.01.41.2-1.0-0.71.01.0-0.8-1.0
Bone: post-yield work1.52.12.81.6-1.6-1.21.51.4-1.0-1.7
Bone: stiffness0.20.31.50.3-0.10.20.10.51.2-0.1
Bone: tissue strength1.21.22.31.0-1.0-1.01.00.7-1.5-1.1
Bone: trabecular number5.58.59.9-2.72.92.9-3.1-2.63.13.0
Bone: trabecular spacing1.82.33.21.8-1.5-1.41.51.6-1.4-1.5
Bone: trabecular thickness0.10.20.4-0.30.30.5-0.6-0.50.10.3
Bone: trabecular tissue density0.10.10.6-0.1-0.1-0.30.1-0.2-0.7-0.2
Breakpoint value in progressive ratio session0.30.40.9-0.90.6-1.0-0.2-0.30.60.4
Distance traveled before self-admin0.10.10.2-0.10.10.50.30.20.4-0.1
Distance traveled after self-admin1.01.11.91.1-1.1-0.51.21.4-0.4-1.2
Delta time in closed arm before/after self-admin3.93.85.32.1-2.1-2.31.62.2-1.1-2.0
Delta time in open arm before/after self-admin0.10.10.2-0.0-0.10.50.20.10.4-0.2
Diff in mean of infusions in LGA sessions0.30.31.3-0.70.3-1.10.0-0.10.30.3
Extinction: sum of active levers before priming1.71.72.31.5-1.2-1.51.31.4-0.8-1.3
Active lever presses in extinction session 62.22.16.2-1.51.50.8-1.2-0.72.51.4
Delta distance traveled before/after self-admin1.41.52.01.3-1.3-1.31.11.4-0.7-1.2
Delta ambulatory time before/after self-admin1.11.21.91.4-1.1-1.00.91.3-0.5-1.1
Time in closed arm before self-admin1.11.23.7-0.90.91.9-1.1-1.20.40.8
Time in closed arm after self-admin0.50.50.80.8-0.9-0.40.60.8-0.3-0.9
Time in open arm before self-admin1.81.95.11.1-1.2-2.31.41.4-0.6-1.1
Time in open arm after self-admin0.40.40.60.6-0.7-0.60.80.6-0.5-0.6
Sum of active levers in priming session hrs 5-60.60.63.0-0.60.5-0.0-0.5-0.21.70.5
Time to tail flick, vehicle, before self-admin0.50.52.50.4-0.00.6-0.3-0.5-1.6-0.1
Time to tail flick, vehicle, after self-admin0.10.10.2-0.30.3-0.0-0.1-0.4-0.50.3
Time to tail flick, test, before self-admin1.31.21.51.1-1.1-1.11.11.1-1.2-1.0
Time to tail flick, test, after self-admin0.30.31.30.1-0.10.7-0.5-0.5-1.10.1
Delta time to tail flick, vehicle, before/after SA0.30.30.5-0.70.60.1-0.3-0.40.60.7
Delta time to tail flick, test, before/after SA1.81.62.8-1.11.01.5-1.6-1.70.11.2
Ambulatory time before self-admin0.00.00.1-0.1-0.00.00.30.1-0.1-0.2
Ambulatory time after self-admin1.71.83.31.5-1.4-0.71.41.8-0.6-1.6
Total heroin consumption2.22.63.3-1.81.71.4-1.7-1.71.21.6
Area under the delay curve0.10.10.3-0.30.30.4-0.5-0.20.20.4
Delay disc. indifference point, 0s delay0.91.01.4-0.91.00.9-1.2-1.10.81.0
Delay disc. indifference point, 16s delay0.30.31.4-0.20.00.6-0.30.01.20.2
Delay disc. indifference point, 2s delay0.70.81.1-0.80.90.8-1.0-1.00.41.0
Delay disc. indifference point, 24s delay0.10.10.50.2-0.30.00.30.2-0.7-0.3
Delay disc. indifference point, 4s delay0.80.81.7-0.90.90.6-0.8-0.51.31.0
Delay disc. indifference point, 8s delay0.10.10.2-0.30.20.4-0.4-0.3-0.30.3
Delay discount exponential model param0.00.00.10.2-0.1-0.30.30.0-0.1-0.2
Delay discount hyperbolic model param0.10.10.20.3-0.3-0.40.40.2-0.2-0.4
Fecal boli incidents, locomotor time 10.50.62.10.7-0.5-0.50.70.3-1.5-0.6
Change in fecal boli incidents, locomotor task0.10.10.20.1-0.3-0.40.20.30.0-0.2
Time >=10cm from walls, locomotor time 10.10.10.3-0.30.3-0.1-0.2-0.5-0.10.3
Bouts of movement, locomotor time 10.20.20.70.3-0.3-0.50.20.90.4-0.4
Total resting periods, locomotor time 10.60.61.50.9-0.8-0.90.61.2-0.2-0.7
Rest time, locomotor task time 10.10.10.3-0.10.20.5-0.5-0.3-0.10.2
Distance moved, locomotor task time 10.00.10.30.2-0.0-0.10.10.10.50.1
Vertical activity count, locomotor time 10.30.31.20.5-0.4-1.10.70.4-0.1-0.4
Time >=10cm from walls, locomotor time 20.80.91.6-1.01.30.2-0.6-1.20.61.2
Bouts of movement, locomotor time 20.50.61.6-0.80.80.5-0.6-0.41.30.6
Total resting periods, locomotor time 20.40.41.4-0.80.60.4-0.4-0.31.20.5
Rest time, locomotor task time 20.60.71.00.9-0.8-1.00.80.9-0.7-0.8
Distance moved, locomotor task time 20.20.20.30.6-0.5-0.40.30.60.2-0.4
Vertical activity count, locomotor time 20.40.50.90.5-0.6-1.00.70.7-0.5-0.7
Weight adjusted by age0.30.41.10.4-0.2-1.10.60.70.7-0.2
Seeking ratio, delayed vs. immediate footshock0.20.20.7-0.90.4-0.1-0.0-0.60.10.4
Locomotion in novel chamber4.96.18.0-2.82.62.1-2.2-2.42.52.6
Locomotion in novel chamber post-restriction1.11.31.8-1.31.31.0-1.1-1.30.51.2
Progressive ratio0.20.30.6-0.60.5-0.1-0.1-0.40.80.6
Food seeking constrained by brief footshock0.40.51.0-0.60.50.9-0.7-0.41.00.7
Seeking ratio, punishment vs. effort0.10.10.20.3-0.30.5-0.10.2-0.4-0.3
Run reversals in cocaine runway, females2.42.43.71.3-1.6-1.91.61.8-0.3-1.6
Run reversals in cocaine runway, males0.40.40.9-0.60.51.0-0.5-0.50.50.5
Latency to leave start box in cocaine runway1.51.62.31.3-1.4-1.21.31.3-0.8-1.5
Latency to leave start box in cocaine runway, F1.51.62.31.3-1.3-1.21.41.5-0.0-1.4
Latency to leave start box in cocaine runway, M0.20.20.4-0.40.20.6-0.6-0.6-0.50.1
Cd content in liver0.10.10.3-0.40.30.6-0.4-0.20.50.2
Co content in liver0.60.71.00.8-0.9-0.80.70.8-1.0-0.8
Cu content in liver0.00.00.1-0.30.0-0.0-0.1-0.00.00.0
Fe content in liver0.91.01.81.1-1.0-1.11.01.40.1-1.0
K content in liver2.22.25.3-1.41.41.1-1.4-0.92.31.4
Mg content in liver1.51.62.8-1.51.21.0-1.1-1.01.71.2
Mn content in liver2.93.34.1-2.01.81.7-1.8-1.71.91.8
Na content in liver0.70.83.3-0.40.70.5-0.6-0.11.80.8
Rb content in liver1.41.72.3-1.31.21.5-1.4-1.50.81.3
Se content in liver6.27.58.1-2.82.82.8-2.7-2.62.72.8
Sr content in liver0.10.10.3-0.50.30.2-0.2-0.6-0.20.3
Zn content in liver3.43.75.0-2.01.92.2-2.0-2.01.11.9