Hub : Genes

Otof

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000009967 0.04 0.05 1.1e-03 0.02 0.02 0.02 0.02 1.3e-03 1.3e-03 9.8e-04 1.6e-03
2 Brain gene expression ENSRNOG00000009967 0.41 0.12 0.0e+00 0.52 0.54 0.54 0.54 2.0e-56 1.2e-59 1.9e-58 8.4e-60
3 Brain intron excision ratio chr6:26022098:26023642 0.03 0.03 3.3e-03 0.02 0.02 0.02 0.02 2.9e-03 6.6e-03 8.6e-03 7.4e-03
4 Brain mRNA stability ENSRNOG00000009967 0.04 0.03 2.2e-03 0.03 0.02 0.01 0.02 1.1e-03 3.9e-03 2.5e-02 3.9e-03
5 IL gene expression ENSRNOG00000009967 0.39 0.3 4.9e-05 0.1 0.11 0.12 0.1 2.7e-03 1.4e-03 1.1e-03 2.6e-03
6 NAcc gene expression ENSRNOG00000009967 0.08 0.06 3.6e-05 0.05 0.06 0.05 0.06 7.0e-05 5.9e-05 2.3e-04 5.5e-05
7 OFC gene expression ENSRNOG00000009967 0.34 0.17 3.7e-07 0.28 0.27 0.28 0.26 1.7e-07 5.1e-07 1.9e-07 8.7e-07
8 PL gene expression ENSRNOG00000009967 0.14 0.09 6.1e-13 0.16 0.16 0.15 0.16 4.8e-12 3.4e-12 1.1e-11 5.0e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail1.85.88.8-2.0-2.8-2.81.2-3.0-1.6-2.5-2.8
BMI without tail0.30.71.2-0.7-0.8-0.90.5-1.1-0.6-1.1-1.0
Body weight2.08.311.5-0.2-3.1-3.42.6-3.3-2.9-3.3-3.0
Epididymis fat weight12.429.038.5-0.2-6.0-5.45.5-6.1-5.6-5.5-6.2
Glucose0.20.20.4-0.3-0.5-0.60.3-0.7-0.4-0.5-0.6
Heart weight5.68.013.71.9-2.4-2.53.7-2.5-3.6-2.8-2.7
Left kidney weight0.41.14.72.21.00.80.20.9-0.10.61.0
Right kidney weight0.72.05.72.4-0.6-0.92.0-0.6-1.9-0.9-0.7
Tail length0.10.31.41.20.70.40.40.4-0.2-0.10.6
Length with tail0.72.44.52.1-0.8-1.32.1-0.9-2.0-1.5-0.8
Length without tail0.51.01.71.2-0.9-1.11.3-0.7-1.3-0.8-0.6
Liver weight, left1.22.03.40.4-1.3-1.51.5-1.4-1.6-1.8-1.4
Liver weight, right7.211.916.71.3-3.2-3.64.1-3.4-4.1-3.8-3.3
Parametrial fat weight6.913.418.9-0.2-4.2-3.43.7-4.2-3.8-3.7-4.3
Retroperitoneal fat weight21.169.899.5-1.3-9.8-8.48.0-9.6-8.4-8.1-10.0
Intraocular pressure5.37.510.00.6-2.8-3.22.9-2.7-3.0-3.2-2.7
Extensor digitorum longus weight2.710.916.3-1.22.63.2-4.03.54.03.83.1
Soleus weight2.67.69.9-0.12.63.0-3.13.03.12.82.9
Tibialis anterior weight1.75.99.7-1.81.22.3-3.12.33.03.11.9
Tibia length1.64.56.41.9-1.7-2.22.5-1.9-2.5-2.4-1.6
Number of licking bursts0.70.81.5-1.0-1.2-1.20.2-0.8-0.6-0.6-1.2
Food consumed during 24 hour testing period0.10.10.4-0.7-0.3-0.0-0.2-0.20.00.3-0.3
Times rat made contact with spout0.91.01.6-0.50.81.3-1.21.01.21.00.8
Mean time between licks in bursts2.02.83.90.4-1.6-1.81.9-1.9-2.0-1.7-1.7
Mean num. licks in bursts0.91.12.50.71.31.6-0.41.00.90.81.3
Std. dev. time between licks in bursts0.91.12.0-0.6-1.2-1.30.5-1.2-0.8-1.4-1.1
Water consumed over 24 hours0.20.30.7-0.90.00.2-0.80.30.70.40.1
Indifference point 0 sec0.50.81.5-0.3-1.2-1.10.5-1.0-0.8-0.8-1.0
Indifference point AUC0.70.82.4-1.5-0.1-0.0-1.40.31.10.80.2
Indifference point function ln k0.91.32.71.61.51.40.01.10.20.61.3
Indifference point function log k0.91.32.71.61.51.40.01.10.20.61.3
Delay discounting total patch changes 0 sec0.50.81.5-0.2-1.2-1.20.5-1.1-0.8-0.9-0.9
Delay discounting total patch changes 12 sec1.01.31.90.1-1.3-1.41.0-1.4-1.1-1.1-1.2
Delay discounting total patch changes 18 sec0.70.91.6-1.0-1.2-1.30.0-1.1-0.4-0.7-1.0
Delay discounting total patch changes 24 sec0.91.11.6-0.3-1.3-1.20.9-1.1-1.1-0.9-1.2
Delay discounting total patch changes 6 sec1.01.63.2-1.6-1.8-1.30.2-1.4-0.5-0.7-1.5
Delay discounting time to switch 0 sec0.10.20.9-0.9-0.4-0.4-0.0-0.4-0.1-0.1-0.5
Delay discounting water rate 0 sec0.50.82.21.50.91.1-0.10.80.20.51.1
Delay discounting water rate 12 sec0.60.92.61.6-0.2-0.21.6-0.2-1.3-0.5-0.4
Delay discounting water rate 18 sec1.01.46.12.51.21.10.90.6-0.40.11.0
Delay discounting water rate 24 sec0.91.22.91.7-0.4-0.61.6-0.7-1.4-1.0-0.5
Delay discounting water rate 6 sec0.71.04.52.10.20.01.4-0.1-1.2-0.50.1
Locomotor activity0.81.33.3-0.1-1.0-1.80.7-1.1-1.1-1.4-0.9
Locomotor testing distance0.30.51.7-1.3-0.7-1.0-0.4-0.30.0-0.2-0.6
Locomotor testing rearing0.71.12.4-1.20.60.2-1.60.91.40.90.9
Light reinforcement 11.52.75.7-2.00.51.2-2.41.12.11.61.1
Light reinforcement 21.51.93.0-1.01.01.4-1.71.21.71.61.3
Reaction time number correct0.30.40.60.10.50.8-0.60.80.60.70.5
Reaction time mean minus median0.10.10.4-0.30.40.6-0.2-0.20.30.3-0.0
Reaction time mean minus median AUC0.00.00.2-0.30.10.20.1-0.4-0.0-0.1-0.2
Reaction time num false alarms1.31.83.9-1.8-2.0-1.60.2-1.3-0.5-0.7-1.4
Reaction time num false alarms AUC1.31.93.9-1.8-2.0-1.60.3-1.4-0.5-0.8-1.5
Reaction time trials correct on left0.30.40.60.10.50.8-0.60.80.60.70.5
Reaction time trials on left0.30.40.60.00.50.8-0.60.80.70.70.5
Reaction time mean0.50.71.81.40.10.01.4-0.7-1.1-0.7-0.3
Reaction time mean AUC0.40.61.61.30.20.11.2-0.6-0.9-0.6-0.2
Median of all reaction times0.71.03.01.70.1-0.11.5-0.6-1.2-0.8-0.2
Reaction time omissions0.20.20.8-0.9-0.4-0.5-0.4-0.40.2-0.5-0.3
Reaction time false alarm rate1.72.44.5-1.8-2.1-1.80.6-1.7-0.8-1.1-1.7
Reaction time premature initiation rate0.10.20.3-0.1-0.4-0.40.5-0.5-0.5-0.4-0.4
Reaction time premature initiations0.00.00.0-0.1-0.1-0.00.1-0.0-0.20.0-0.1
Std. dev. reaction times0.10.20.30.1-0.00.10.6-0.6-0.5-0.3-0.5
Reaction time trials completed0.30.40.60.00.50.8-0.60.80.70.70.5
Reaction time trials AUC0.40.50.8-0.10.50.9-0.80.90.80.90.6
Social response proportion0.30.31.31.20.40.50.4-0.0-0.2-0.50.3
Social responses0.10.20.30.2-0.5-0.20.4-0.6-0.3-0.5-0.4
Social time0.30.42.11.50.40.40.5-0.1-0.4-0.30.3
Conditioned locomotion3.64.36.30.02.22.3-2.02.32.02.52.1
Cocaine response after cond. corrected0.20.20.5-0.10.40.3-0.70.20.6-0.10.5
Cocaine response after cond. not corrected0.70.71.3-0.10.90.9-1.10.81.00.60.9
Cocaine response before conditioning2.12.54.50.21.61.9-1.21.81.42.11.7
Saline control response0.91.22.00.61.01.0-0.91.40.91.41.3
Condit. Reinf. active minus inactive responses3.03.85.6-1.81.12.0-2.41.82.32.41.4
Condit. Reinf. active-inactive response ratio0.91.01.8-0.60.71.1-1.10.91.11.40.9
Condit. Reinf. active responses2.53.55.8-2.00.92.0-2.41.52.42.11.2
Condit. Reinf. inactive responses1.21.52.7-1.60.41.3-1.70.81.61.00.6
Condit. Reinf. lever presses1.92.55.2-0.91.21.9-1.61.51.62.31.3
Condit. Reinf. lever reinforcers received2.33.35.2-2.00.81.9-2.31.52.32.01.1
Pavlov. Cond. lever latency1.31.83.00.8-1.2-1.61.4-1.2-1.5-1.7-1.1
Pavlov. Cond. magazine entry latency0.30.31.2-1.10.00.2-0.50.20.50.9-0.0
Pavlov. Cond. change in total contacts0.40.61.7-0.80.30.8-0.70.60.71.30.2
Pavlov. Cond. index score0.81.12.4-0.90.71.1-1.00.91.11.60.7
Pavlov. Cond. latency score0.81.12.7-0.90.81.1-1.00.91.01.70.7
Pavlov. Cond. lever contacts0.60.81.8-0.60.71.1-0.90.80.91.40.6
Pavlov. Cond. magazine entry number0.10.20.80.90.2-0.10.20.1-0.2-0.60.3
Pavlov. Cond. intertrial magazine entries2.63.44.20.3-1.9-1.92.0-1.9-1.9-2.1-1.9
Pavlov. Cond. lever-magazine prob. diff.0.50.71.8-1.00.40.8-0.80.60.81.30.3
Pavlov. Cond. response bias1.01.32.5-1.00.91.3-1.31.01.31.60.8
Conditioned reinforcement - actives3.23.25.41.12.31.8-1.42.11.51.62.0
Conditioned reinforcement - inactives3.33.86.40.82.51.7-1.82.21.91.72.4
Conditioned locomotion2.53.04.91.22.22.0-1.12.01.41.62.0
Intermittent access intake day 1-15 change1.11.12.21.51.51.0-0.41.10.40.61.3
Intermittent access intake escalation0.60.61.71.31.20.6-0.20.80.20.30.9
Intermittent access intake escalation 20.20.20.60.8-0.1-0.40.5-0.2-0.6-0.5-0.2
Intermitt. access day 1 inactive lever presses0.10.10.2-0.00.20.3-0.30.30.40.40.2
Intermitt. access day 15 inactive lever presses4.55.08.7-2.31.41.9-2.91.72.92.51.6
Intermitt. access escalation Index1.91.72.5-1.6-1.6-1.60.4-1.4-0.7-1.1-1.5
Intermittent access day 1 total infusions4.44.96.3-0.42.22.4-2.42.42.52.52.2
Intermittent access day 15 total infusions3.13.55.41.02.31.9-1.62.21.71.82.2
Intermittent access terminal intake (last 3 days)2.83.14.70.72.21.9-1.42.01.61.82.0
Intermittent access total infusions3.74.16.51.02.62.1-1.62.31.81.92.4
Intermittent access day 1 locomotion1.91.92.60.21.51.4-1.41.61.41.51.6
Intermittent access day 15 total locomotion0.60.61.00.31.00.7-0.90.90.80.80.8
Intermittent access total locomotion0.70.81.50.71.20.7-0.71.10.70.71.0
Intermittent access standard deviation0.50.50.80.70.90.6-0.60.90.60.60.9
Cocaine induced anxiety0.10.10.4-0.50.1-0.1-0.60.20.50.30.2
Post-drug Anxiety1.51.72.40.1-1.3-1.61.3-1.4-1.4-1.5-1.3
Baseline Anxiety1.31.42.20.3-1.2-0.81.5-1.4-1.4-1.2-1.3
Lifetime Intake4.55.17.60.82.82.3-2.02.62.22.22.6
Incentive Sensitization - Responses0.70.73.21.81.10.20.30.5-0.2-0.11.0
Incentive Sensitization - Breakpoint0.60.63.11.80.80.00.50.3-0.4-0.30.7
Progressive ratio test 1 active lever presses2.52.64.10.32.01.6-1.61.81.61.61.8
Progressive ratio test 1 breakpoint2.12.13.20.21.81.4-1.51.61.51.51.6
Progressive ratio test 1 inactive lever presses5.45.87.2-0.32.72.5-2.42.62.62.62.5
Progressive ratio test 2 active lever presses1.21.32.81.51.70.9-0.41.20.60.71.4
Progressive ratio test 2 breakpoint1.31.42.91.51.71.1-0.51.30.70.81.5
Progressive ratio test 2 inactive lever presses2.52.93.90.22.01.7-1.71.91.81.81.9
Total sessions with >9 infusions5.05.48.50.62.92.2-2.12.72.32.12.8
Short access day 1 total inactive lever presses3.53.95.2-0.22.21.8-2.32.32.32.02.0
Short access day 10 total inactive lever presses0.60.62.6-1.6-0.30.3-1.00.20.90.8-0.1
Short access day 1 total infusions5.35.67.6-0.52.52.2-2.72.52.82.42.5
Short access day 10 total infusions5.25.78.10.72.92.4-2.22.82.42.32.8
Short access total infusions4.44.87.00.52.62.2-2.12.52.32.12.5
Short access day 1 locomotion7.68.010.6-1.02.83.1-3.02.93.33.22.7
Short access day 10 total locomotion1.11.21.80.21.21.3-0.81.21.01.21.2
Short access total locomotion1.81.83.00.71.71.6-0.91.51.21.31.6
Compulsive drug intake2.42.44.1-0.9-1.9-2.00.8-1.7-1.2-1.6-1.8
One hour access (0.3 mA shock)1.82.13.30.81.81.2-1.51.81.41.21.7
One hour access (shock baseline)4.14.87.91.32.82.3-1.72.61.82.02.6
Number of responses in last shaping day1.71.72.70.81.71.5-1.11.31.21.21.6
Context. condit. distance diff. score0.20.20.70.80.40.60.20.3-0.00.30.4
Locomotion velocity, session 10.60.71.9-0.9-1.0-1.40.2-0.7-0.6-0.5-0.8
Locomotion distance, session 10.50.71.6-0.80.20.1-1.11.00.81.30.6
Locomotion velocity, session 20.20.20.50.7-0.3-0.30.7-0.1-0.7-0.3-0.2
Locomotion distance, session 20.10.10.4-0.2-0.6-0.50.2-0.0-0.30.2-0.3
Locomotion velocity, session 30.70.82.1-1.10.10.8-1.00.71.01.40.3
Locomotion distance, session 30.40.41.3-1.1-0.40.1-0.80.30.71.0-0.0
Stereotopy head waving bouts, day 32.22.64.4-0.61.62.1-1.71.51.91.51.6
Stereotopy head waving duration, day 30.50.61.2-0.10.91.1-0.60.60.80.60.9
Locomotion velocity, session 70.50.51.6-1.3-0.10.5-0.90.10.90.60.0
Locomotion distance, session 70.50.71.6-1.2-1.1-1.00.1-0.7-0.2-0.3-1.0
Stereotopy head waving bouts, day 70.00.00.3-0.0-0.10.60.1-0.10.0-0.0-0.0
Stereotopy head waving duration, day 70.60.81.7-0.30.71.3-0.80.80.91.10.7
Locomotion velocity, session 80.40.50.80.40.80.8-0.40.90.40.80.8
Locomotion distance, session 80.20.30.70.30.50.8-0.20.70.40.70.6
Degree of sensitization distance0.90.91.60.1-0.8-1.11.0-1.0-1.0-1.3-1.0
Degree of sensitization stereotypy0.20.20.4-0.0-0.6-0.00.5-0.5-0.4-0.3-0.5
Condit. Reinf. active minus inactive responses1.31.52.3-0.7-1.4-1.50.8-1.3-1.0-1.2-1.4
Condit. Reinf. active-inactive response ratio1.01.01.8-0.6-1.2-1.40.6-1.1-0.9-0.9-1.3
Condit. Reinf. active responses0.10.10.5-0.7-0.3-0.3-0.1-0.20.0-0.2-0.3
Condit. Reinf. inactive responses0.70.91.3-0.10.91.1-0.91.11.00.81.1
Incentive salience index mean0.20.20.4-0.6-0.5-0.6-0.1-0.4-0.1-0.5-0.4
Condit. Reinf. lever presses0.30.40.70.10.70.7-0.60.70.7-0.00.8
Time in familiar zone, hab. session 11.00.92.20.1-0.9-1.50.8-1.0-1.0-0.8-0.9
Time in novel zone, hab. session 10.10.10.2-0.2-0.40.10.4-0.3-0.2-0.2-0.4
Total zone transitions, hab. session 10.10.10.30.50.30.20.00.60.10.40.4
Total locomotion distance, hab. session 10.50.71.60.81.01.3-0.20.80.60.40.9
Locomotion velocity, hab. session 11.01.53.10.51.41.7-0.81.31.11.01.4
Time in familiar zone, hab. session 20.20.20.3-0.4-0.6-0.5-0.0-0.5-0.2-0.0-0.5
Time in novel zone, hab. session 20.10.10.40.4-0.1-0.30.6-0.1-0.4-0.4-0.1
Total zone transitions, hab. session 20.20.20.6-0.7-0.8-0.5-0.0-0.1-0.10.4-0.5
Total locomotion distance, hab. session 20.10.20.8-0.9-0.6-0.2-0.2-0.20.10.4-0.5
Locomotion velocity, hab. session 20.20.20.9-1.0-0.40.0-0.5-0.00.30.6-0.3
Novel to familiar place preference ratio0.60.61.10.2-0.8-0.21.0-0.9-0.9-1.0-0.8
Novelty place preference0.91.01.60.3-1.0-0.51.3-1.1-1.1-1.1-1.0
Time in novel zone, NPP test0.91.01.70.3-1.0-0.51.3-1.1-1.1-1.2-1.0
Total zone transitions, NPP test0.81.22.3-0.50.80.7-1.21.41.11.51.1
Total locomotion distance, NPP test1.31.82.6-0.71.11.2-1.61.51.51.61.3
Locomotion velocity, NPP test1.82.63.8-0.81.31.5-2.01.81.91.91.6
Pavlov. Cond. lever latency0.60.81.60.7-0.6-0.51.3-1.0-1.1-1.0-0.8
Pavlov. Cond. magazine entry latency0.10.10.2-0.4-0.3-0.3-0.10.0-0.00.4-0.2
Pavlov. Cond. change in total contacts0.00.00.00.00.00.00.00.2-0.00.10.2
Pavlov. Cond. index score0.20.20.5-0.70.10.0-0.70.50.60.60.3
Pavlov. Cond. latency score0.20.20.6-0.8-0.1-0.2-0.70.40.50.60.1
Pavlov. Cond. lever contacts0.40.40.7-0.40.50.5-0.90.80.80.70.7
Pavlov. Cond. magazine entry number0.20.20.70.80.1-0.00.6-0.3-0.5-0.7-0.1
Pavlov. Cond. intertrial magazine entries1.51.83.10.41.81.5-1.11.51.31.01.6
Pavlov. Cond. lever-magazine prob. diff.0.60.81.3-0.70.60.6-1.21.01.01.10.7
Pavlov. Cond. response bias1.01.21.9-0.41.01.0-1.21.21.21.41.1
Bone: apparent density2.84.66.6-0.32.22.0-2.62.42.52.12.3
Bone surface0.81.42.7-0.70.90.6-1.61.21.41.51.0
Bone volume1.22.02.90.01.51.3-1.71.61.61.31.6
Bone: connectivity density2.23.56.2-0.81.61.2-2.52.02.22.21.8
Bone: cortical apparent density0.20.21.0-0.20.30.1-0.30.60.31.00.2
Bone: cortical area0.10.10.4-0.0-0.6-0.5-0.2-0.2-0.00.2-0.2
Bone: cortical porosity2.72.94.80.31.82.2-1.51.81.71.81.9
Bone: cortical porosity2.02.23.70.51.61.9-1.31.51.41.41.7
Bone: cortical thickness0.30.40.70.5-0.8-0.60.7-0.7-0.7-0.3-0.7
Bone: cortical thickness0.60.71.4-0.20.60.7-1.10.91.01.20.7
Bone: cortical tissue density0.10.20.8-0.20.2-0.1-0.20.50.20.90.1
Bone: elastic displacement1.31.52.30.51.51.4-1.11.31.31.11.4
Bone: elastic work0.60.81.3-0.10.80.8-1.10.71.11.00.8
Bone: endosteal estimation0.10.20.6-0.50.2-0.3-0.80.40.50.50.4
Bone: endosteal perimeter0.00.10.1-0.4-0.2-0.4-0.4-0.10.2-0.00.0
Bone: final force0.00.10.30.2-0.3-0.5-0.1-0.0-0.10.3-0.1
Bone: final moment0.00.10.30.1-0.3-0.5-0.20.0-0.10.3-0.1
Bone: marrow area0.10.20.6-0.60.2-0.2-0.80.40.60.50.4
Bone: maximum diameter0.10.30.8-0.8-0.3-0.3-0.90.10.60.50.1
Bone: maximum force0.10.10.40.3-0.4-0.60.0-0.2-0.3-0.0-0.2
Bone: maximum moment0.00.10.30.2-0.3-0.5-0.1-0.1-0.10.1-0.1
Bone: minimum diameter0.50.92.00.1-1.4-1.40.6-1.0-0.9-0.6-0.9
Bone: periosteal estimation0.10.20.5-0.10.0-0.2-0.70.40.50.60.4
Bone: periosteal perimeter0.00.10.2-0.1-0.4-0.4-0.2-0.20.00.2-0.1
Bone: post-yield work1.01.42.51.01.51.1-0.91.40.90.91.6
Bone: stiffness0.10.20.60.2-0.7-0.80.3-0.3-0.5-0.2-0.4
Bone: tissue strength0.60.51.10.6-0.5-0.41.1-0.7-0.9-0.7-0.7
Bone: trabecular number2.33.65.20.12.21.7-2.32.02.21.52.2
Bone: trabecular spacing1.62.03.90.9-1.2-1.12.0-1.3-1.8-1.6-1.1
Bone: trabecular thickness0.40.50.7-0.10.80.8-0.80.60.80.60.7
Bone: trabecular tissue density0.40.51.4-0.10.70.7-0.50.90.51.20.5
Breakpoint value in progressive ratio session0.91.02.1-0.51.00.5-1.50.91.20.81.1
Distance traveled before self-admin0.20.20.70.40.60.8-0.10.60.10.40.4
Distance traveled after self-admin0.60.61.20.6-0.4-0.71.0-0.6-1.1-1.0-0.6
Delta time in closed arm before/after self-admin0.50.41.2-0.2-0.9-1.10.1-0.8-0.4-0.7-0.6
Delta time in open arm before/after self-admin0.20.20.4-0.50.30.3-0.60.40.60.50.3
Diff in mean of infusions in LGA sessions0.10.10.5-0.40.1-0.0-0.70.10.40.20.2
Extinction: sum of active levers before priming0.20.20.50.30.4-0.2-0.50.60.40.20.7
Active lever presses in extinction session 61.11.01.70.21.20.8-1.01.11.20.91.3
Delta distance traveled before/after self-admin1.71.82.4-0.3-1.5-1.51.2-1.6-1.3-1.4-1.4
Delta ambulatory time before/after self-admin0.50.50.7-0.2-0.8-0.90.6-0.9-0.6-0.8-0.7
Time in closed arm before self-admin0.20.20.30.1-0.2-0.50.5-0.5-0.6-0.5-0.4
Time in closed arm after self-admin0.80.81.30.2-0.7-1.20.8-0.9-1.0-1.0-0.9
Time in open arm before self-admin0.10.10.10.2-0.3-0.20.3-0.3-0.2-0.2-0.2
Time in open arm after self-admin0.60.71.2-0.70.50.6-1.00.81.10.90.7
Sum of active levers in priming session hrs 5-60.40.42.0-1.4-0.7-0.5-0.5-0.40.4-0.0-0.3
Time to tail flick, vehicle, before self-admin0.90.91.60.2-0.8-0.81.3-1.1-1.2-1.0-0.9
Time to tail flick, vehicle, after self-admin3.33.56.2-0.5-2.0-1.81.7-2.1-1.9-1.9-2.5
Time to tail flick, test, before self-admin0.80.81.6-0.11.30.9-0.80.80.90.91.0
Time to tail flick, test, after self-admin0.50.51.71.30.90.70.20.5-0.10.20.8
Delta time to tail flick, vehicle, before/after SA0.60.61.5-1.0-1.1-0.5-0.1-0.7-0.2-0.4-1.2
Delta time to tail flick, test, before/after SA1.00.91.31.11.11.1-0.51.00.50.71.1
Ambulatory time before self-admin0.20.20.60.10.60.8-0.00.70.20.50.4
Ambulatory time after self-admin0.30.40.90.6-0.3-0.40.9-0.3-0.8-0.7-0.4
Total heroin consumption1.41.73.2-0.71.30.9-1.81.21.51.31.3
Area under the delay curve0.10.10.10.3-0.1-0.30.2-0.2-0.3-0.3-0.3
Delay disc. indifference point, 0s delay2.93.24.81.4-1.1-1.72.2-1.6-2.2-2.2-1.4
Delay disc. indifference point, 16s delay0.10.10.2-0.5-0.30.1-0.1-0.10.10.2-0.3
Delay disc. indifference point, 2s delay0.30.30.60.7-0.5-0.40.8-0.4-0.7-0.6-0.4
Delay disc. indifference point, 24s delay1.41.32.40.91.61.1-0.71.40.81.01.5
Delay disc. indifference point, 4s delay0.20.20.4-0.1-0.4-0.60.2-0.5-0.4-0.6-0.5
Delay disc. indifference point, 8s delay0.00.00.20.40.20.10.00.1-0.00.00.1
Delay discount exponential model param0.00.00.0-0.1-0.10.00.1-0.1-0.00.00.0
Delay discount hyperbolic model param0.00.00.0-0.10.00.10.1-0.0-0.00.10.1
Fecal boli incidents, locomotor time 11.51.62.81.41.71.3-0.51.50.70.91.7
Change in fecal boli incidents, locomotor task4.03.85.20.4-1.8-2.22.0-2.2-2.1-2.3-1.9
Time >=10cm from walls, locomotor time 10.30.31.21.10.60.20.30.3-0.30.00.5
Bouts of movement, locomotor time 11.31.42.8-1.7-0.01.4-1.30.61.41.50.2
Total resting periods, locomotor time 11.61.83.8-1.90.01.6-1.50.71.61.70.3
Rest time, locomotor task time 10.30.41.3-0.60.11.1-0.50.40.60.70.2
Distance moved, locomotor task time 11.01.12.10.8-0.4-1.41.2-0.8-1.3-1.3-0.6
Vertical activity count, locomotor time 10.70.71.10.5-0.5-1.01.0-0.8-1.0-1.0-0.6
Time >=10cm from walls, locomotor time 20.90.91.71.01.31.0-0.41.10.50.81.2
Bouts of movement, locomotor time 20.30.30.7-0.3-0.8-0.10.6-0.6-0.6-0.2-0.8
Total resting periods, locomotor time 20.30.30.8-0.8-0.90.10.3-0.6-0.20.1-0.8
Rest time, locomotor task time 20.91.02.4-1.5-0.11.2-1.20.51.21.10.1
Distance moved, locomotor task time 20.50.61.11.00.3-0.91.0-0.3-0.9-0.90.0
Vertical activity count, locomotor time 20.30.31.31.10.6-0.10.60.2-0.4-0.40.5
Weight adjusted by age0.40.41.9-1.4-0.80.2-0.4-0.40.30.4-0.6
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.2-0.30.00.0-0.10.20.1-0.1
Locomotion in novel chamber0.40.51.00.2-0.6-0.71.0-0.7-0.8-0.7-0.8
Locomotion in novel chamber post-restriction2.83.35.4-0.6-2.1-2.31.4-2.1-1.6-1.8-1.9
Progressive ratio0.10.20.3-0.40.30.3-0.50.20.50.40.4
Food seeking constrained by brief footshock8.09.817.21.73.72.9-2.63.62.82.94.2
Seeking ratio, punishment vs. effort0.91.11.81.21.20.9-0.61.30.60.81.3
Run reversals in cocaine runway, females0.40.41.11.00.80.70.30.5-0.20.20.5
Run reversals in cocaine runway, males0.80.81.21.01.11.1-0.41.00.40.81.0
Latency to leave start box in cocaine runway0.60.71.1-0.01.01.1-0.80.80.80.80.7
Latency to leave start box in cocaine runway, F0.30.30.6-0.60.50.5-0.70.40.80.50.4
Latency to leave start box in cocaine runway, M1.71.72.50.71.61.6-1.01.51.11.31.3
Cd content in liver0.20.30.7-0.4-0.7-0.80.2-0.6-0.4-0.1-0.5
Co content in liver4.75.57.9-0.12.52.7-2.42.32.42.82.5
Cu content in liver0.00.10.10.10.2-0.2-0.30.20.10.30.3
Fe content in liver0.10.10.2-0.0-0.0-0.5-0.30.30.20.20.4
K content in liver1.41.42.9-1.0-1.5-1.70.5-1.3-0.8-1.1-1.3
Mg content in liver1.71.84.0-0.5-1.7-2.00.6-1.5-1.0-1.3-1.3
Mn content in liver0.60.72.2-1.5-0.7-0.2-1.1-0.10.80.8-0.4
Na content in liver0.80.81.70.71.21.0-0.70.90.90.21.3
Rb content in liver0.50.61.5-1.1-0.8-1.20.0-0.7-0.4-0.5-0.7
Se content in liver0.80.92.9-0.7-1.3-1.70.4-0.9-0.7-0.3-1.0
Sr content in liver0.30.20.50.40.0-0.00.7-0.6-0.5-0.7-0.3
Zn content in liver1.61.82.50.1-1.5-1.61.3-1.5-1.5-1.0-1.4