Cacul1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000009954 0.1 0.05 1.5e-06 0.03 0.04 0.04 0.03 2.2e-04 7.9e-05 5.6e-05 1.2e-04
2 BLA gene expression ENSRNOG00000009954 0.23 0.13 9.4e-07 0.16 0.11 0.14 0.15 9.5e-09 2.3e-06 9.4e-08 2.8e-08
3 BLA isoform ratio ENSRNOT00000084760 0.07 0.05 7.0e-03 0 0 -0 -0 2.4e-01 3.1e-01 5.5e-01 4.9e-01
4 Brain gene expression ENSRNOG00000009954 0.16 0.07 1.1e-13 0.15 0.15 0.15 0.15 1.3e-13 4.8e-14 6.8e-14 1.1e-13
5 Brain isoform ratio ENSRNOT00000050617 0.14 0.07 7.4e-10 0.11 0.11 0.11 0.1 3.3e-10 5.3e-10 3.4e-10 1.1e-09
6 Brain isoform ratio ENSRNOT00000084760 0.12 0.07 4.3e-09 0.1 0.09 0.1 0.09 2.1e-09 5.8e-09 5.6e-10 9.4e-09
7 Brain intron excision ratio chr1:259677583:259686255 0.12 0.06 5.5e-09 0.08 0.09 0.1 0.09 7.2e-08 1.0e-08 1.6e-09 2.1e-08
8 Brain mRNA stability ENSRNOG00000009954 0.03 0.02 5.5e-03 0.01 0 0 0.01 2.3e-02 9.7e-02 3.0e-01 8.4e-02
9 IL gene expression ENSRNOG00000009954 0.24 0.14 4.4e-03 0.05 0.05 0.06 0.03 2.3e-02 2.7e-02 1.6e-02 5.7e-02
10 Liver gene expression ENSRNOG00000009954 0.23 0.1 0.0e+00 0.16 0.15 0.14 0.16 2.7e-17 8.4e-17 1.8e-15 1.3e-17
11 Liver isoform ratio ENSRNOT00000050617 0.03 0.02 3.8e-03 0.02 0.02 0.02 0.01 1.3e-03 6.1e-03 5.4e-03 8.4e-03
12 Liver isoform ratio ENSRNOT00000084760 0.03 0.02 3.4e-03 0.01 0.02 0.01 0.01 7.5e-03 4.5e-03 6.2e-02 1.3e-02
13 Liver mRNA stability ENSRNOG00000009954 0.03 0.02 7.2e-03 0.01 0 0.01 0 1.4e-02 8.7e-02 2.6e-02 1.0e-01
14 NAcc gene expression ENSRNOG00000009954 0.11 0.06 5.8e-05 0.05 0.05 0.05 0.04 7.3e-05 8.4e-05 2.1e-04 4.7e-04
15 NAcc isoform ratio ENSRNOT00000050617 0.05 0.03 9.5e-04 0.05 0.05 0.04 0.05 1.7e-04 9.6e-05 3.4e-04 2.0e-04
16 NAcc isoform ratio ENSRNOT00000084760 0.05 0.03 9.6e-04 0.05 0.05 0.03 0.04 2.4e-04 1.6e-04 4.8e-03 3.8e-04
17 OFC gene expression ENSRNOG00000009954 0.45 0.14 1.0e-08 0.24 0.41 0.39 0.37 2.3e-06 9.5e-11 3.5e-10 8.6e-10
18 PL gene expression ENSRNOG00000009954 0.24 0.1 2.4e-13 0.16 0.17 0.18 0.16 6.7e-12 6.2e-13 2.4e-13 1.8e-12
19 PL isoform ratio ENSRNOT00000050617 0.03 0.02 8.8e-03 0.02 0.01 0.01 0.01 1.8e-02 7.3e-02 6.1e-02 2.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
BMI with tail25.883.5147.77.55.4-10.16.812.1-9.710.55.42.44.911.5-9.712.25.611.5-11.68.47.611.9
BMI without tail18.137.964.24.74.1-7.24.67.7-6.97.34.02.33.57.2-6.87.54.27.8-7.85.75.38.0
Body weight24.2102.3175.18.36.4-11.37.813.1-10.911.56.13.26.012.2-10.813.26.612.7-12.79.48.613.1
Epididymis fat weight36.184.3138.67.66.1-9.87.411.5-10.010.66.23.66.111.3-10.011.86.411.2-11.29.07.811.1
Glucose4.36.614.70.61.7-3.61.32.6-3.43.81.51.61.22.3-3.62.41.83.5-3.52.31.63.0
Heart weight6.18.719.31.71.7-4.41.83.6-3.33.71.30.91.03.6-3.33.41.83.9-3.92.52.44.0
Left kidney weight7.722.052.34.82.3-5.13.86.9-4.24.32.30.22.36.0-4.16.62.75.8-5.93.84.17.2
Right kidney weight7.421.148.74.61.9-4.83.76.9-4.14.22.1-0.12.56.1-4.06.82.35.7-5.73.83.77.0
Tail length0.72.24.50.61.4-2.11.11.2-1.91.61.41.31.20.9-1.70.91.31.8-1.81.31.32.1
Length with tail2.810.117.52.32.3-4.02.53.9-3.63.62.11.52.13.2-3.43.82.44.0-4.03.02.94.2
Length without tail4.610.019.52.92.1-3.42.74.2-3.23.31.81.01.93.7-3.14.42.33.9-3.93.02.93.9
Liver weight, left6.610.717.62.32.1-3.82.34.2-3.94.22.31.22.33.6-3.84.22.04.0-4.03.32.63.6
Liver weight, right12.019.932.13.83.3-4.23.75.6-5.05.23.02.13.25.1-4.95.73.35.4-5.34.54.05.1
Parametrial fat weight24.447.777.45.44.3-7.25.48.8-7.88.05.02.85.18.2-7.88.54.58.5-8.56.95.78.3
Retroperitoneal fat weight39.6130.9225.19.26.9-12.38.714.8-12.613.57.13.66.714.6-12.515.07.314.2-14.210.99.513.9
Intraocular pressure1.11.63.30.71.3-0.91.20.9-1.41.11.51.51.60.8-1.40.91.31.1-1.01.61.81.0
Extensor digitorum longus weight1.87.113.72.42.0-2.32.43.2-2.72.91.81.11.92.9-2.83.41.93.3-3.32.62.33.7
Soleus weight1.33.910.10.8-0.2-2.80.43.1-1.72.2-0.1-1.10.02.5-1.93.1-0.12.7-2.81.00.63.2
Tibialis anterior weight0.20.81.80.71.0-0.50.91.0-1.00.91.10.70.90.3-0.91.10.91.1-1.10.80.81.3
Tibia length0.41.12.10.90.7-1.40.81.4-1.11.30.80.20.41.0-1.01.30.71.2-1.20.91.11.2
Number of licking bursts0.50.61.50.31.0-0.30.80.4-1.00.81.01.21.10.1-1.00.21.00.6-0.61.00.80.3
Food consumed during 24 hour testing period0.50.62.11.10.8-0.60.90.8-0.50.40.70.30.60.6-0.60.70.70.8-0.80.71.11.4
Times rat made contact with spout1.51.84.61.31.1-1.41.21.6-1.21.10.70.60.81.3-1.21.41.11.6-1.61.21.62.1
Mean time between licks in bursts1.31.94.71.51.90.51.90.4-0.90.42.12.12.20.4-0.90.41.90.5-0.51.61.80.5
Mean num. licks in bursts0.30.31.30.5-0.5-0.5-0.10.70.4-0.2-0.7-1.1-0.80.70.40.6-0.50.3-0.3-0.40.11.0
Std. dev. time between licks in bursts0.50.51.80.90.91.40.9-0.40.2-0.50.90.90.9-0.40.4-0.30.9-0.60.60.50.9-0.5
Water consumed over 24 hours0.10.10.80.2-0.2-0.0-0.10.10.3-0.4-0.5-0.4-0.3-0.20.3-0.2-0.20.1-0.1-0.30.20.9
Indifference point 0 sec4.26.812.91.30.9-3.61.43.5-3.03.31.30.31.43.5-3.13.50.93.4-3.42.31.63.2
Indifference point AUC0.20.30.9-0.9-0.9-0.5-0.60.2-0.30.4-0.4-0.40.30.2-0.60.5-0.80.3-0.30.0-0.9-0.1
Indifference point function ln k0.30.41.81.30.60.10.70.8-0.10.30.2-0.2-0.11.1-0.00.90.50.5-0.50.30.81.0
Indifference point function log k0.30.41.81.30.60.10.70.8-0.10.30.2-0.2-0.11.1-0.00.90.50.5-0.50.30.81.0
Delay discounting total patch changes 0 sec4.98.015.01.51.0-3.91.53.8-3.23.51.40.31.53.8-3.33.91.03.7-3.72.51.73.5
Delay discounting total patch changes 12 sec3.44.58.61.00.8-2.91.22.7-2.62.61.20.61.72.7-2.62.80.92.7-2.72.01.42.5
Delay discounting total patch changes 18 sec2.23.05.40.90.7-2.01.12.3-2.12.11.20.61.62.1-2.12.20.82.2-2.21.71.01.8
Delay discounting total patch changes 24 sec0.60.82.0-0.3-0.3-1.30.11.0-1.21.20.60.11.21.0-1.41.1-0.11.0-1.00.9-0.10.4
Delay discounting total patch changes 6 sec3.55.310.20.70.4-3.01.13.0-2.82.91.50.42.13.0-3.13.20.53.0-3.02.20.92.4
Delay discounting time to switch 0 sec0.91.33.3-0.50.01.4-0.4-1.61.2-1.6-0.10.3-0.3-1.81.3-1.8-0.1-1.51.5-0.9-0.3-1.5
Delay discounting water rate 0 sec1.93.07.60.90.1-2.30.72.5-1.72.20.4-0.50.42.8-1.92.70.22.3-2.31.30.62.2
Delay discounting water rate 12 sec2.23.35.91.10.9-2.41.12.1-1.92.31.10.60.82.4-2.22.31.12.4-2.41.61.22.3
Delay discounting water rate 18 sec0.50.71.90.2-0.7-1.2-0.11.1-0.30.7-0.5-1.1-0.51.4-0.41.2-0.40.9-0.90.0-0.31.3
Delay discounting water rate 24 sec2.02.88.10.8-0.5-2.20.32.6-1.11.8-0.3-1.3-0.32.6-1.42.8-0.32.1-2.20.70.22.6
Delay discounting water rate 6 sec0.91.33.41.00.1-1.40.51.8-0.91.20.2-0.60.31.7-1.01.90.11.5-1.50.70.31.7
Locomotor activity0.10.10.40.10.30.20.1-0.20.0-0.30.50.40.1-0.60.2-0.50.3-0.30.3-0.10.2-0.0
Locomotor testing distance0.50.82.0-0.4-0.50.6-0.6-1.01.1-1.4-0.4-0.5-0.6-1.31.2-1.2-0.6-1.11.1-1.0-0.5-0.4
Locomotor testing rearing0.71.22.2-1.3-1.10.0-1.3-1.31.2-1.0-1.2-0.9-1.2-1.10.7-1.2-1.1-0.80.8-1.3-1.5-0.4
Light reinforcement 10.20.31.00.3-0.70.3-0.30.20.6-0.9-0.8-1.0-0.20.00.70.1-0.7-0.40.4-0.4-0.3-0.1
Light reinforcement 20.20.20.70.30.40.70.1-0.50.3-0.5-0.20.4-0.2-0.90.6-0.70.5-0.50.6-0.20.2-0.6
Reaction time number correct0.30.41.2-0.00.6-0.80.30.8-1.11.10.60.50.30.1-0.70.60.60.7-0.70.40.50.7
Reaction time mean minus median0.70.93.0-1.2-1.1-0.4-1.3-0.60.6-0.2-1.7-1.1-1.4-0.20.4-0.2-1.3-0.50.4-1.0-1.4-0.8
Reaction time mean minus median AUC2.12.76.2-2.1-2.0-0.5-2.3-1.01.2-0.5-2.5-1.9-2.5-0.70.9-0.8-2.2-0.90.8-1.9-2.3-1.0
Reaction time num false alarms1.01.43.81.80.9-0.91.31.9-0.90.70.70.00.51.5-0.61.40.91.2-1.21.01.71.7
Reaction time num false alarms AUC1.01.44.01.50.8-1.31.02.0-1.00.90.5-0.10.21.5-0.71.40.81.3-1.30.81.61.9
Reaction time trials correct on left0.30.41.2-0.00.6-0.80.30.8-1.11.10.60.50.30.1-0.70.60.60.7-0.70.40.50.7
Reaction time trials on left0.30.41.2-0.00.6-0.80.30.8-1.11.10.60.50.30.1-0.70.60.60.7-0.70.50.50.7
Reaction time mean3.24.47.4-2.7-2.01.1-2.5-2.31.8-1.5-2.5-1.4-2.1-2.01.7-2.1-2.2-2.12.1-2.2-2.4-2.4
Reaction time mean AUC4.35.78.8-3.0-2.31.3-2.8-2.52.2-1.9-2.7-1.7-2.4-2.22.0-2.3-2.5-2.42.4-2.5-2.8-2.7
Median of all reaction times3.85.18.3-2.9-2.21.3-2.6-2.52.0-1.7-2.5-1.5-2.2-2.21.9-2.4-2.4-2.32.3-2.4-2.6-2.6
Reaction time omissions0.10.10.5-0.4-0.00.4-0.1-0.30.0-0.0-0.00.30.4-0.1-0.2-0.3-0.0-0.30.30.2-0.1-0.7
Reaction time false alarm rate0.71.12.81.60.6-0.91.01.7-0.60.50.4-0.10.31.5-0.51.20.71.0-1.00.81.51.4
Reaction time premature initiation rate0.40.51.6-0.4-1.2-0.0-0.8-0.10.20.5-1.1-1.2-0.90.80.30.4-1.1-0.20.2-0.5-0.7-0.1
Reaction time premature initiations0.20.30.9-0.4-0.8-0.5-0.60.3-0.31.0-0.8-0.9-0.70.8-0.20.7-0.70.3-0.3-0.2-0.40.5
Std. dev. reaction times0.50.72.5-1.1-0.9-0.4-1.2-0.50.5-0.1-1.6-0.9-1.3-0.10.3-0.3-1.1-0.40.4-0.8-1.1-0.7
Reaction time trials completed0.30.41.2-0.00.6-0.80.30.8-1.11.10.60.50.30.1-0.70.60.60.7-0.70.50.50.7
Reaction time trials AUC0.50.81.80.30.9-1.00.51.1-1.31.30.80.70.40.3-0.90.80.81.0-1.00.70.71.1
Social response proportion1.61.84.42.01.1-0.31.52.1-1.21.01.30.51.11.6-0.61.61.21.1-1.11.31.71.3
Social responses3.24.17.21.61.4-1.81.72.6-2.52.71.30.91.72.5-2.22.51.42.3-2.32.11.72.0
Social time0.10.10.6-0.30.1-0.8-0.10.2-0.40.6-0.30.2-0.00.1-0.40.10.10.4-0.40.1-0.10.2
Conditioned locomotion0.20.20.8-0.8-0.30.3-0.6-0.50.1-0.1-0.3-0.1-0.2-0.90.3-0.6-0.5-0.50.5-0.5-0.7-0.5
Cocaine response after cond. corrected2.73.17.60.1-1.52.4-0.9-1.12.6-2.8-1.5-1.9-1.2-1.12.6-1.1-1.5-2.12.1-1.7-1.3-1.6
Cocaine response after cond. not corrected3.03.39.50.1-1.12.8-0.6-1.72.7-3.1-1.0-1.1-0.7-1.62.5-1.7-1.0-2.32.3-1.6-1.1-1.8
Cocaine response before conditioning0.81.04.40.41.40.41.0-0.7-0.50.01.42.11.4-0.7-0.7-0.71.50.1-0.10.90.90.1
Saline control response1.41.94.1-1.7-1.60.5-1.7-1.21.1-1.0-1.0-1.2-1.2-1.61.1-1.3-1.5-1.21.2-1.6-2.0-1.3
Condit. Reinf. active minus inactive responses2.43.04.31.21.9-1.81.61.5-2.12.01.61.81.51.3-2.01.52.02.0-2.01.81.71.5
Condit. Reinf. active-inactive response ratio1.81.94.40.51.2-2.10.91.1-1.61.70.71.20.71.0-1.91.21.31.8-1.81.31.11.6
Condit. Reinf. active responses3.75.17.91.72.2-2.02.12.3-2.82.82.02.02.02.1-2.62.32.32.5-2.52.52.11.8
Condit. Reinf. inactive responses2.02.53.71.41.6-0.91.61.7-1.91.91.71.41.41.7-1.61.61.71.6-1.61.81.51.0
Condit. Reinf. lever presses2.33.24.91.41.3-1.61.62.2-2.22.21.41.11.71.9-2.02.21.42.1-2.11.91.51.8
Condit. Reinf. lever reinforcers received2.84.05.71.72.1-1.42.01.9-2.42.32.02.02.01.8-2.21.92.22.1-2.02.31.91.4
Pavlov. Cond. lever latency2.83.85.5-1.8-1.91.1-2.0-2.12.3-2.1-2.0-1.7-2.3-1.42.0-2.1-1.9-1.91.9-2.3-2.0-1.6
Pavlov. Cond. magazine entry latency0.30.31.10.30.5-0.10.40.3-0.81.00.70.80.60.2-0.70.10.60.3-0.30.80.6-0.3
Pavlov. Cond. change in total contacts0.91.32.40.91.2-0.51.21.1-1.41.41.11.21.50.6-1.21.11.21.0-1.01.41.00.6
Pavlov. Cond. index score1.11.52.71.11.1-0.51.21.3-1.61.61.31.11.50.9-1.31.31.11.1-1.11.51.10.5
Pavlov. Cond. latency score1.11.42.41.11.0-0.41.21.4-1.51.61.31.01.61.0-1.31.31.11.1-1.11.51.00.5
Pavlov. Cond. lever contacts1.62.23.51.21.3-0.91.51.7-1.91.81.51.31.81.0-1.61.61.41.5-1.51.71.51.2
Pavlov. Cond. magazine entry number0.20.21.0-0.2-0.20.1-0.2-0.60.8-1.0-0.3-0.3-0.4-0.20.6-0.5-0.2-0.30.3-0.6-0.30.3
Pavlov. Cond. intertrial magazine entries1.62.15.51.10.4-2.00.82.0-1.11.00.6-0.20.72.2-1.42.10.41.9-1.91.00.82.3
Pavlov. Cond. lever-magazine prob. diff.0.70.92.00.80.8-0.30.91.1-1.31.40.90.91.20.6-1.11.00.90.8-0.81.20.80.3
Pavlov. Cond. response bias1.92.64.11.41.7-0.61.71.5-2.01.81.91.82.00.9-1.71.41.81.4-1.42.01.81.0
Conditioned reinforcement - actives3.93.99.8-0.9-0.12.6-0.9-2.52.1-2.6-0.70.1-0.8-3.12.5-3.0-0.4-2.62.6-1.8-0.7-2.1
Conditioned reinforcement - inactives0.10.20.5-0.2-0.10.3-0.1-0.70.4-0.60.10.10.5-0.50.2-0.4-0.3-0.50.5-0.0-0.2-0.7
Conditioned locomotion2.22.67.2-0.20.12.5-0.3-2.01.7-2.3-0.00.3-0.0-2.72.2-2.50.1-2.22.2-1.3-0.1-1.5
Intermittent access intake day 1-15 change0.10.10.2-0.5-0.1-0.4-0.1-0.2-0.2-0.00.10.30.2-0.4-0.2-0.50.10.1-0.1-0.1-0.30.1
Intermittent access intake escalation0.20.20.3-0.5-0.5-0.1-0.4-0.40.4-0.6-0.5-0.3-0.2-0.50.4-0.5-0.3-0.30.3-0.5-0.6-0.1
Intermittent access intake escalation 20.10.10.30.20.3-0.50.40.2-0.40.10.30.40.5-0.2-0.2-0.10.50.3-0.30.20.30.6
Intermitt. access day 1 inactive lever presses0.91.02.30.40.2-1.10.60.9-1.11.20.70.41.11.5-1.51.20.21.3-1.31.20.20.8
Intermitt. access day 15 inactive lever presses0.60.72.6-0.7-1.0-1.6-0.70.3-0.50.8-0.7-0.9-0.50.8-0.80.7-1.00.8-0.8-0.1-0.90.7
Intermitt. access escalation Index0.20.20.60.60.50.30.5-0.20.00.00.80.50.7-0.20.1-0.10.7-0.00.00.20.50.3
Intermittent access day 1 total infusions0.40.51.3-0.6-0.30.8-0.5-1.10.8-0.8-0.3-0.1-0.2-0.80.7-0.8-0.5-0.90.9-0.6-0.5-0.9
Intermittent access day 15 total infusions0.70.71.5-0.9-0.70.6-0.8-1.10.9-1.1-0.6-0.3-0.4-1.20.9-1.2-0.6-0.90.9-0.9-0.8-0.8
Intermittent access terminal intake (last 3 days)0.30.40.8-0.8-0.60.4-0.6-0.70.5-0.7-0.4-0.2-0.2-0.80.5-0.9-0.4-0.60.6-0.6-0.7-0.6
Intermittent access total infusions0.91.02.1-0.9-0.61.2-0.7-1.41.1-1.2-0.4-0.1-0.2-1.41.1-1.4-0.5-1.21.2-0.9-0.8-1.2
Intermittent access day 1 locomotion2.12.14.0-1.0-1.22.0-1.2-1.41.8-1.8-0.9-1.0-0.7-1.51.7-1.3-1.3-1.81.8-1.4-1.2-1.8
Intermittent access day 15 total locomotion0.10.10.3-0.40.0-0.3-0.10.1-0.50.40.10.30.3-0.0-0.50.1-0.00.3-0.30.3-0.0-0.1
Intermittent access total locomotion0.91.11.9-0.7-0.71.4-0.7-0.91.2-1.4-0.7-0.6-0.4-1.31.3-1.0-0.8-1.31.3-1.0-0.7-1.2
Intermittent access standard deviation0.30.31.2-0.40.40.30.0-0.8-0.2-0.20.51.00.5-1.10.1-1.00.7-0.40.4-0.0-0.0-0.5
Cocaine induced anxiety2.93.36.6-0.7-0.52.5-0.8-2.52.0-2.2-0.5-0.2-0.7-2.62.4-2.6-0.5-2.52.5-1.7-1.0-2.0
Post-drug Anxiety0.50.51.5-0.40.11.2-0.1-1.10.7-0.6-0.10.3-0.0-1.10.8-1.0-0.1-1.01.0-0.5-0.4-1.1
Baseline Anxiety2.12.24.70.50.7-1.61.01.8-1.92.10.80.81.11.9-2.21.90.71.9-1.91.70.71.2
Lifetime Intake1.21.42.5-1.0-0.91.4-0.9-1.61.4-1.4-0.8-0.4-0.4-1.41.2-1.4-0.9-1.41.4-1.1-1.1-1.4
Incentive Sensitization - Responses0.50.52.2-0.2-0.1-1.5-0.21.0-0.90.9-0.0-0.20.00.5-0.90.5-0.11.1-1.10.20.11.3
Incentive Sensitization - Breakpoint0.50.51.9-0.10.0-1.4-0.10.9-0.90.90.1-0.00.20.4-0.90.50.11.0-1.10.30.21.2
Progressive ratio test 1 active lever presses1.41.42.5-1.0-1.11.2-1.1-1.61.4-1.4-0.7-0.8-0.7-1.11.2-1.1-1.1-1.41.4-1.1-1.1-1.4
Progressive ratio test 1 breakpoint1.41.52.6-1.2-1.31.1-1.2-1.61.4-1.3-0.9-0.8-0.8-1.01.1-1.2-1.3-1.41.4-1.2-1.3-1.4
Progressive ratio test 1 inactive lever presses0.20.20.8-0.1-0.50.8-0.1-0.60.5-0.60.3-0.10.7-0.10.3-0.1-0.5-0.60.60.1-0.4-0.9
Progressive ratio test 2 active lever presses0.20.30.7-0.8-0.8-0.6-0.8-0.10.10.0-0.6-0.7-0.6-0.2-0.0-0.2-0.70.1-0.1-0.5-0.70.3
Progressive ratio test 2 breakpoint0.30.30.8-0.9-0.9-0.7-0.80.00.1-0.0-0.6-0.7-0.4-0.2-0.1-0.1-0.80.1-0.1-0.5-0.70.3
Progressive ratio test 2 inactive lever presses0.10.10.70.50.30.00.40.0-0.20.10.70.30.80.3-0.30.30.40.3-0.30.50.30.3
Total sessions with >9 infusions1.21.32.5-0.7-1.41.1-1.1-1.01.6-1.5-1.4-1.4-0.5-0.61.2-0.4-1.5-1.21.2-1.0-1.3-1.2
Short access day 1 total inactive lever presses0.40.52.60.90.71.30.8-0.20.4-0.70.70.61.6-0.20.2-0.10.2-0.40.50.60.4-0.6
Short access day 10 total inactive lever presses1.71.95.51.60.3-1.41.12.0-0.90.90.3-0.41.22.3-1.42.00.11.7-1.81.30.71.8
Short access day 1 total infusions0.90.92.4-0.3-0.91.5-0.7-0.81.3-1.3-0.8-0.8-0.2-0.51.0-0.5-1.0-1.21.2-0.7-0.8-1.3
Short access day 10 total infusions2.02.24.8-1.3-0.81.6-1.1-2.21.7-1.7-1.0-0.3-0.9-1.91.6-1.9-0.9-1.91.9-1.4-1.1-1.7
Short access total infusions2.02.23.2-1.2-1.41.5-1.3-1.71.8-1.7-1.3-1.0-0.8-1.31.5-1.4-1.5-1.81.8-1.4-1.4-1.8
Short access day 1 locomotion0.60.71.2-0.8-1.10.6-0.9-0.70.9-0.9-1.1-0.8-0.3-0.50.6-0.4-1.1-0.80.8-0.7-1.0-1.0
Short access day 10 total locomotion0.30.41.2-0.5-0.51.1-0.4-0.30.5-0.6-0.3-0.4-0.4-0.70.8-0.5-0.4-0.80.8-0.6-0.5-0.9
Short access total locomotion3.43.45.3-1.6-2.31.6-2.0-1.42.1-1.8-2.0-2.1-1.8-1.31.9-1.0-2.2-1.91.9-2.0-2.1-1.9
Compulsive drug intake0.80.82.21.30.9-0.11.20.9-0.50.30.80.71.51.1-0.81.00.70.7-0.71.20.90.5
One hour access (0.3 mA shock)0.30.41.0-0.70.10.6-0.2-1.00.3-0.70.10.60.9-1.00.1-0.9-0.2-0.60.6-0.1-0.3-0.8
One hour access (shock baseline)1.11.33.1-1.2-0.71.1-0.9-1.71.1-1.3-0.6-0.1-0.2-1.71.0-1.6-0.7-1.31.3-1.1-1.0-1.1
Number of responses in last shaping day0.60.62.2-0.4-0.51.1-0.6-1.51.1-0.7-0.5-0.4-0.1-0.70.7-0.6-0.6-1.01.0-0.5-0.6-1.1
Context. condit. distance diff. score0.30.40.70.80.60.00.80.6-0.60.80.60.40.40.8-0.40.60.60.4-0.40.80.80.3
Locomotion velocity, session 10.91.02.5-0.4-0.11.3-0.4-1.61.1-1.2-0.40.3-0.6-1.31.2-1.50.1-1.31.3-0.8-0.3-1.2
Locomotion distance, session 12.12.84.0-1.3-1.41.5-1.5-1.71.8-1.6-1.7-1.2-1.7-1.72.0-1.7-1.4-2.02.0-1.8-1.4-1.8
Locomotion velocity, session 21.51.82.9-0.5-1.01.7-1.0-1.51.7-1.6-0.9-0.9-1.2-1.11.7-1.4-1.0-1.61.6-1.4-1.3-1.7
Locomotion distance, session 20.20.31.00.5-0.5-0.6-0.00.80.00.3-0.5-1.0-0.50.80.10.9-0.40.4-0.4-0.10.10.7
Locomotion velocity, session 31.61.93.2-1.2-1.21.4-1.1-1.71.6-1.8-1.0-0.6-0.8-1.51.5-1.7-1.1-1.81.8-1.3-0.8-1.4
Locomotion distance, session 30.80.91.6-0.4-0.61.2-0.5-1.21.2-1.3-0.7-0.4-0.6-1.01.2-1.1-0.5-1.21.2-0.8-0.4-0.9
Stereotopy head waving bouts, day 31.31.52.3-1.5-1.20.6-1.4-1.11.3-1.2-1.4-1.1-1.3-1.51.3-1.1-1.2-1.21.2-1.5-1.3-0.9
Stereotopy head waving duration, day 31.82.23.9-2.0-1.70.5-1.9-1.41.2-1.0-1.6-1.3-1.6-1.41.2-1.4-1.6-1.31.2-1.7-1.9-1.2
Locomotion velocity, session 70.10.10.50.40.10.00.30.2-0.20.40.10.10.10.7-0.30.20.10.1-0.10.40.4-0.0
Locomotion distance, session 71.01.23.41.80.7-0.51.31.3-0.70.70.80.10.81.8-0.71.40.71.0-1.01.11.41.5
Stereotopy head waving bouts, day 70.70.83.9-2.0-0.5-0.5-1.3-1.1-0.10.6-0.80.2-1.0-1.3-0.1-1.1-0.5-0.50.5-0.7-0.9-1.0
Stereotopy head waving duration, day 71.11.46.4-2.5-0.8-0.3-1.7-1.5-0.00.5-0.90.2-1.1-1.70.0-1.4-0.7-0.80.8-0.9-1.3-1.6
Locomotion velocity, session 80.40.51.80.40.41.40.5-0.90.5-0.80.20.70.4-0.90.8-0.90.5-1.01.0-0.00.7-0.4
Locomotion distance, session 80.30.42.01.40.60.71.10.20.2-0.20.30.30.40.60.40.30.7-0.20.20.51.20.4
Degree of sensitization distance3.03.15.72.01.3-1.31.72.1-1.71.71.40.71.42.4-1.72.11.32.0-2.01.81.72.2
Degree of sensitization stereotypy0.50.62.9-1.7-0.3-0.9-1.0-0.4-0.81.4-0.50.3-0.6-0.7-0.7-0.4-0.30.1-0.1-0.2-0.8-0.7
Condit. Reinf. active minus inactive responses0.60.72.41.51.01.31.30.10.2-0.51.00.80.90.00.40.11.1-0.40.40.71.4-0.3
Condit. Reinf. active-inactive response ratio0.50.62.00.70.71.40.6-0.80.7-0.90.30.70.1-0.70.8-0.90.7-0.90.9-0.00.7-0.7
Condit. Reinf. active responses2.63.17.62.81.8-0.12.42.1-1.31.12.01.21.91.8-1.02.11.91.3-1.32.12.31.0
Condit. Reinf. inactive responses4.65.510.62.71.9-1.52.53.2-2.32.12.31.12.42.6-2.03.31.92.5-2.52.62.31.9
Incentive salience index mean0.60.73.41.91.00.91.50.60.0-0.30.90.60.90.50.30.51.0-0.00.10.91.50.1
Condit. Reinf. lever presses0.30.42.21.50.50.31.00.8-0.0-0.10.40.00.60.70.20.70.50.1-0.10.71.10.2
Time in familiar zone, hab. session 10.80.82.5-0.20.1-1.6-0.11.0-1.11.6-0.4-0.2-0.40.9-1.11.00.11.2-1.20.30.11.2
Time in novel zone, hab. session 11.31.33.2-0.10.31.80.1-1.61.0-1.50.50.90.6-1.51.1-1.60.4-1.51.6-0.30.2-1.7
Total zone transitions, hab. session 10.50.72.1-1.0-1.4-0.1-1.10.10.20.3-1.3-1.3-1.00.10.40.1-1.3-0.30.3-0.7-1.2-0.5
Total locomotion distance, hab. session 10.10.10.30.00.10.30.30.1-0.40.50.10.40.5-0.1-0.20.10.2-0.10.10.40.1-0.4
Locomotion velocity, hab. session 10.10.10.40.40.20.30.50.4-0.40.60.20.30.70.2-0.30.40.20.1-0.10.60.2-0.2
Time in familiar zone, hab. session 21.31.33.61.01.6-0.31.50.2-1.10.81.41.91.50.5-1.00.21.60.5-0.51.51.80.5
Time in novel zone, hab. session 20.50.51.3-0.6-0.80.1-0.9-0.20.6-0.4-1.1-1.0-1.2-0.40.6-0.2-0.8-0.20.2-0.9-1.0-0.3
Total zone transitions, hab. session 20.20.31.0-0.6-0.9-0.4-0.70.20.10.3-1.0-0.9-0.7-0.00.10.2-0.80.0-0.0-0.4-0.60.0
Total locomotion distance, hab. session 20.50.61.10.60.6-0.80.71.1-0.91.10.10.40.60.6-0.91.00.61.0-1.00.90.70.8
Locomotion velocity, hab. session 20.40.61.20.40.3-0.90.51.1-0.91.1-0.10.10.40.7-0.91.10.31.0-1.00.70.40.8
Novel to familiar place preference ratio1.01.02.31.21.50.21.30.5-0.70.41.41.41.20.7-0.60.51.50.5-0.51.11.40.3
Novelty place preference0.60.71.81.01.30.31.10.2-0.40.11.21.31.00.4-0.30.21.30.2-0.20.81.20.1
Time in novel zone, NPP test1.61.74.21.42.00.01.70.5-1.10.81.62.01.40.7-0.90.52.00.7-0.71.41.80.4
Total zone transitions, NPP test0.30.51.50.9-0.3-0.60.41.2-0.40.6-0.2-0.70.21.2-0.41.2-0.10.7-0.70.50.20.8
Total locomotion distance, NPP test0.30.41.41.00.1-0.20.71.2-0.50.60.2-0.20.61.0-0.41.20.30.6-0.60.70.50.5
Locomotion velocity, NPP test0.20.31.10.7-0.70.20.20.90.3-0.3-0.1-1.00.20.80.20.9-0.60.2-0.20.1-0.20.3
Pavlov. Cond. lever latency0.50.61.6-0.8-0.31.2-0.5-1.20.5-0.80.10.30.1-1.00.5-1.1-0.2-1.01.0-0.5-0.8-1.2
Pavlov. Cond. magazine entry latency1.11.52.21.31.0-1.31.21.5-1.11.10.60.50.81.3-1.11.41.01.4-1.41.21.41.5
Pavlov. Cond. change in total contacts3.74.06.01.92.2-2.12.02.1-2.01.91.41.51.41.7-1.92.02.02.2-2.22.02.52.3
Pavlov. Cond. index score1.62.03.11.51.2-1.61.41.7-1.41.40.80.60.91.5-1.31.61.21.7-1.61.41.61.8
Pavlov. Cond. latency score1.31.62.61.41.1-1.51.21.6-1.21.20.60.60.81.4-1.21.51.01.5-1.51.31.51.6
Pavlov. Cond. lever contacts1.11.32.60.90.8-1.60.91.5-1.21.40.40.40.51.2-1.21.30.81.4-1.41.01.21.5
Pavlov. Cond. magazine entry number1.62.03.0-1.7-1.51.2-1.6-1.61.4-1.2-1.1-0.9-1.2-1.41.3-1.6-1.4-1.51.5-1.5-1.7-1.5
Pavlov. Cond. intertrial magazine entries2.73.26.52.31.1-1.51.82.5-1.51.51.60.31.42.4-1.42.51.21.9-1.91.71.82.1
Pavlov. Cond. lever-magazine prob. diff.1.92.43.41.61.5-1.61.51.8-1.51.50.90.81.11.5-1.41.71.31.8-1.71.61.81.9
Pavlov. Cond. response bias1.01.22.11.20.9-1.31.01.4-1.01.10.50.30.51.2-0.91.30.81.3-1.31.01.31.4
Bone: apparent density5.79.513.03.32.8-2.43.23.6-3.12.92.81.92.83.1-2.83.62.83.3-3.33.23.53.4
Bone surface4.27.410.92.92.5-2.52.73.2-2.82.82.11.42.02.9-2.53.22.43.1-3.02.73.23.3
Bone volume6.010.216.83.12.5-3.22.84.1-3.43.42.41.22.33.5-3.14.02.43.8-3.83.13.24.0
Bone: connectivity density1.42.24.32.01.7-1.01.81.5-1.31.21.31.11.41.7-1.11.61.51.3-1.31.72.11.4
Bone: cortical apparent density6.88.914.2-2.0-2.43.6-2.3-3.23.4-3.7-1.6-1.8-1.8-3.13.5-3.3-2.3-3.83.8-2.9-2.8-3.7
Bone: cortical area10.015.124.93.02.3-4.42.85.0-4.34.82.61.22.44.8-4.35.02.35.0-5.03.63.04.8
Bone: cortical porosity1.71.92.81.11.2-1.61.21.5-1.41.21.01.01.31.3-1.61.41.11.6-1.61.51.51.7
Bone: cortical porosity2.62.84.71.11.4-2.21.31.8-1.91.81.11.11.31.5-2.01.71.32.1-2.01.71.62.1
Bone: cortical thickness5.28.516.42.31.2-3.41.94.1-3.03.51.70.21.64.0-3.24.11.23.8-3.82.51.83.8
Bone: cortical thickness2.32.78.30.2-0.7-2.9-0.12.4-1.41.8-0.3-1.2-0.12.4-1.72.4-0.62.2-2.20.7-0.02.4
Bone: cortical tissue density7.39.515.5-2.1-2.43.8-2.4-3.43.5-3.8-1.6-1.7-1.8-3.33.7-3.5-2.3-3.93.9-3.0-2.8-3.9
Bone: elastic displacement0.70.71.5-1.2-1.0-0.1-1.2-0.80.9-0.9-0.9-0.8-1.0-0.90.6-0.7-1.0-0.50.4-1.1-1.2-0.2
Bone: elastic work0.71.03.1-0.8-1.2-1.8-1.10.70.00.3-1.0-1.6-1.30.3-0.20.6-1.20.8-0.8-0.7-0.71.5
Bone: endosteal estimation1.83.86.81.61.5-2.41.52.4-2.12.21.10.80.92.0-2.02.31.52.5-2.51.72.02.6
Bone: endosteal perimeter1.93.88.50.71.1-2.90.92.4-2.52.90.70.50.52.2-2.32.31.12.7-2.71.51.22.3
Bone: final force5.59.018.22.21.4-3.81.94.3-3.23.61.30.21.33.5-3.14.11.44.0-4.02.52.24.1
Bone: final moment6.210.220.22.41.7-4.02.14.4-3.43.71.70.41.53.7-3.34.31.74.2-4.22.72.64.5
Bone: marrow area2.04.27.31.71.5-2.51.62.5-2.22.41.20.81.02.2-2.12.41.62.6-2.61.82.12.7
Bone: maximum diameter6.111.119.12.22.4-3.82.53.9-4.14.42.51.82.33.6-3.93.82.44.1-4.13.32.83.8
Bone: maximum force5.49.418.52.71.7-3.62.34.3-3.13.41.60.31.43.6-3.04.21.73.9-3.92.62.74.3
Bone: maximum moment6.010.421.02.92.0-3.82.54.4-3.23.41.90.61.73.8-3.14.31.94.1-4.12.83.04.6
Bone: minimum diameter5.19.415.82.22.2-3.72.33.7-3.43.71.91.31.73.4-3.43.62.24.0-4.02.82.63.9
Bone: periosteal estimation6.513.322.12.92.3-4.32.74.7-4.04.42.21.02.04.4-3.94.62.34.7-4.73.33.14.7
Bone: periosteal perimeter6.410.719.71.81.8-4.41.84.1-3.94.41.60.91.44.0-3.84.11.84.4-4.42.82.14.0
Bone: post-yield work2.94.06.12.51.9-1.02.32.3-1.91.91.81.21.82.3-1.72.41.92.0-2.02.32.31.8
Bone: stiffness2.33.67.71.91.2-2.11.52.8-1.92.20.80.20.82.3-1.72.61.12.4-2.41.61.62.5
Bone: tissue strength0.20.21.1-0.70.20.4-0.2-0.70.1-0.40.20.60.2-1.00.1-0.80.1-0.50.5-0.10.0-0.5
Bone: trabecular number3.04.66.62.12.0-2.02.22.5-2.22.01.71.31.92.2-2.12.61.92.4-2.42.32.32.2
Bone: trabecular spacing1.92.45.8-0.8-0.32.4-0.6-2.31.6-1.9-0.30.5-0.3-2.01.5-2.4-0.2-2.12.1-1.0-0.9-2.3
Bone: trabecular thickness8.710.518.82.01.6-4.22.04.2-3.63.82.00.71.93.8-3.74.31.74.3-4.32.92.44.3
Bone: trabecular tissue density0.91.33.6-0.2-0.41.9-0.4-1.41.2-1.40.3-0.2-0.3-1.41.6-1.4-0.3-1.61.6-0.9-0.5-1.4
Breakpoint value in progressive ratio session1.31.44.0-0.10.5-2.00.41.3-1.71.50.60.71.11.0-1.81.00.21.6-1.61.10.61.4
Distance traveled before self-admin3.53.85.7-2.1-2.40.7-2.3-1.11.9-1.9-2.1-2.2-2.3-1.61.9-1.6-2.4-1.71.7-2.3-2.3-1.3
Distance traveled after self-admin2.52.83.8-1.6-1.81.2-1.6-1.61.9-2.0-1.4-1.4-1.4-1.51.8-1.6-1.8-1.81.8-1.8-1.7-1.6
Delta time in closed arm before/after self-admin0.20.20.91.00.20.70.60.10.5-0.6-0.1-0.10.30.30.50.20.3-0.20.20.10.60.2
Delta time in open arm before/after self-admin2.72.56.41.02.1-0.51.90.6-1.81.52.52.52.20.6-1.60.52.11.2-1.21.91.40.7
Diff in mean of infusions in LGA sessions0.20.21.2-1.0-0.0-1.1-0.40.0-0.70.6-0.20.30.1-0.3-0.8-0.2-0.40.4-0.40.1-0.20.3
Extinction: sum of active levers before priming0.20.20.6-0.10.3-0.30.4-0.1-0.60.60.30.70.70.4-0.80.40.40.4-0.40.70.2-0.3
Active lever presses in extinction session 60.90.83.8-0.9-0.8-2.0-0.60.8-0.70.9-0.8-0.7-0.20.8-1.11.0-1.01.0-1.00.2-0.50.9
Delta distance traveled before/after self-admin0.20.31.00.20.30.90.2-1.00.5-0.40.40.40.5-0.50.4-0.60.3-0.60.6-0.00.1-0.6
Delta ambulatory time before/after self-admin0.20.20.70.40.30.80.4-0.60.3-0.30.60.40.7-0.20.2-0.30.3-0.40.40.20.2-0.5
Time in closed arm before self-admin0.40.41.2-1.1-0.6-0.1-0.8-0.80.30.1-0.8-0.4-0.9-0.40.3-0.6-0.7-0.50.4-0.7-0.8-0.6
Time in closed arm after self-admin0.80.91.7-0.6-0.70.6-0.7-1.21.3-1.1-1.2-0.7-0.9-0.81.2-1.0-0.8-1.01.0-1.0-0.7-0.7
Time in open arm before self-admin0.91.02.8-0.7-0.41.0-0.9-1.20.9-1.1-0.5-0.2-0.7-1.71.1-1.4-0.3-1.21.2-1.0-0.6-1.2
Time in open arm after self-admin0.70.83.3-0.01.3-0.00.8-0.2-1.10.91.61.81.0-0.6-0.8-0.51.40.3-0.30.80.6-0.3
Sum of active levers in priming session hrs 5-60.10.10.6-0.10.2-0.10.1-0.5-0.1-0.20.30.50.8-0.4-0.3-0.3-0.00.0-0.00.20.10.1
Time to tail flick, vehicle, before self-admin1.21.32.21.31.2-0.11.30.8-1.11.01.51.11.40.9-1.01.21.50.9-0.91.31.20.7
Time to tail flick, vehicle, after self-admin0.30.30.70.30.1-0.80.40.7-0.70.90.20.10.10.8-0.60.60.20.7-0.80.40.20.9
Time to tail flick, test, before self-admin2.22.13.1-1.2-1.51.0-1.5-1.21.6-1.6-1.8-1.5-1.5-1.31.6-1.2-1.7-1.51.5-1.7-1.5-1.1
Time to tail flick, test, after self-admin0.90.92.20.90.9-0.11.10.7-0.90.91.11.01.51.0-1.10.91.00.8-0.81.30.70.3
Delta time to tail flick, vehicle, before/after SA0.80.83.3-1.0-0.9-1.8-0.80.6-0.71.1-0.9-0.8-1.10.7-0.80.4-0.90.9-0.9-0.3-0.70.9
Delta time to tail flick, test, before/after SA5.75.16.92.22.2-1.12.62.0-2.42.32.52.12.52.3-2.32.22.52.2-2.22.62.21.8
Ambulatory time before self-admin2.22.33.9-1.7-1.90.4-1.8-0.61.4-1.6-1.8-1.7-1.8-1.21.4-1.2-2.0-1.31.3-1.8-1.8-1.0
Ambulatory time after self-admin3.03.34.9-1.7-1.91.5-1.7-1.82.0-2.2-1.4-1.3-1.2-1.81.9-1.9-1.9-2.02.0-1.8-1.9-1.9
Total heroin consumption2.53.010.2-0.10.2-3.20.42.1-2.22.30.30.20.61.9-2.42.1-0.02.4-2.41.30.62.2
Area under the delay curve0.70.73.3-1.8-1.1-1.1-1.5-0.2-0.20.6-0.8-0.7-1.3-0.3-0.3-0.1-1.00.0-0.1-0.7-0.9-0.3
Delay disc. indifference point, 0s delay0.30.31.6-0.3-0.6-1.3-0.30.5-0.20.3-0.7-0.6-0.60.5-0.30.7-0.30.6-0.6-0.1-0.10.7
Delay disc. indifference point, 16s delay0.50.52.5-1.6-0.5-0.6-1.2-0.5-0.40.9-0.7-0.2-1.3-0.6-0.2-0.5-0.4-0.10.1-0.6-0.7-0.4
Delay disc. indifference point, 2s delay1.01.12.6-1.6-1.6-0.4-1.5-0.50.7-0.4-1.1-1.3-1.6-0.50.6-0.4-1.4-0.60.6-1.2-1.3-0.8
Delay disc. indifference point, 24s delay0.40.41.9-1.4-0.8-0.9-1.20.0-0.30.5-0.7-0.5-0.9-0.2-0.4-0.2-0.80.1-0.2-0.4-0.6-0.1
Delay disc. indifference point, 4s delay0.60.62.5-1.6-0.9-0.9-1.3-0.30.10.2-0.8-0.6-1.2-0.4-0.1-0.3-0.9-0.10.1-0.7-0.8-0.3
Delay disc. indifference point, 8s delay0.90.93.1-1.8-1.3-0.4-1.6-0.60.4-0.1-1.1-0.9-1.2-0.60.2-0.5-1.3-0.50.5-1.0-1.2-0.7
Delay discount exponential model param0.80.94.02.01.21.11.70.20.1-0.51.00.81.50.30.30.21.20.0-0.00.81.10.3
Delay discount hyperbolic model param0.91.04.12.01.31.01.70.3-0.0-0.41.00.91.50.40.10.31.30.1-0.10.91.20.5
Fecal boli incidents, locomotor time 10.30.41.4-0.10.9-0.60.30.0-0.91.20.40.9-0.10.1-0.70.20.90.6-0.60.50.40.3
Change in fecal boli incidents, locomotor task1.31.22.91.70.9-0.61.31.3-0.70.41.20.51.31.3-0.81.21.01.0-1.01.21.41.5
Time >=10cm from walls, locomotor time 10.10.10.20.20.30.50.3-0.2-0.1-0.00.20.40.3-0.30.1-0.20.4-0.20.20.20.2-0.3
Bouts of movement, locomotor time 10.60.62.20.50.8-0.40.80.3-0.80.51.51.11.20.1-0.70.11.00.6-0.60.80.70.8
Total resting periods, locomotor time 10.30.41.50.50.6-0.40.70.2-0.50.31.20.70.90.1-0.50.10.80.5-0.50.60.50.9
Rest time, locomotor task time 10.20.21.21.0-0.1-0.10.40.30.4-0.60.2-0.60.00.30.50.3-0.10.1-0.1-0.20.21.1
Distance moved, locomotor task time 10.50.51.9-1.4-1.1-0.1-1.1-0.30.3-0.0-1.2-0.6-0.7-0.20.1-0.2-0.9-0.40.4-0.5-1.0-1.0
Vertical activity count, locomotor time 10.60.61.4-1.2-1.20.3-1.1-0.30.5-0.4-1.1-0.8-0.9-0.30.5-0.3-1.1-0.70.7-0.7-0.9-1.2
Time >=10cm from walls, locomotor time 20.40.51.70.80.0-0.30.61.3-0.60.50.1-0.20.41.2-0.51.20.20.7-0.70.70.40.4
Bouts of movement, locomotor time 20.50.51.4-0.5-0.20.5-0.5-1.20.9-1.1-0.4-0.0-0.4-1.20.7-1.2-0.2-0.80.8-0.8-0.5-0.5
Total resting periods, locomotor time 20.70.81.8-0.8-0.50.5-0.7-1.31.0-1.3-0.5-0.2-0.5-1.30.9-1.3-0.4-0.90.9-0.9-0.7-0.6
Rest time, locomotor task time 20.40.51.4-0.5-0.30.4-0.5-1.10.8-1.0-0.3-0.2-0.3-1.20.8-1.1-0.4-0.80.7-0.8-0.5-0.1
Distance moved, locomotor task time 20.10.20.80.1-0.6-0.3-0.00.7-0.20.4-0.2-0.50.00.9-0.20.8-0.40.2-0.20.2-0.2-0.2
Vertical activity count, locomotor time 20.20.20.70.5-0.20.20.30.7-0.30.30.3-0.20.40.8-0.10.8-0.00.1-0.10.50.1-0.5
Weight adjusted by age3.74.28.71.51.1-2.71.42.7-2.22.21.10.30.72.6-2.22.60.92.7-2.71.61.52.9
Seeking ratio, delayed vs. immediate footshock3.54.011.6-0.4-0.63.4-0.7-2.32.3-2.5-0.5-0.3-0.4-2.22.5-2.3-0.7-2.92.9-1.3-0.9-3.1
Locomotion in novel chamber0.50.72.70.0-1.2-0.7-0.40.90.2-0.1-1.0-1.6-0.61.00.11.2-1.50.3-0.3-0.3-0.40.6
Locomotion in novel chamber post-restriction1.72.05.9-1.1-2.20.0-1.6-0.21.3-1.1-2.0-2.4-1.9-0.11.20.0-2.2-0.90.8-1.5-1.5-0.6
Progressive ratio3.44.05.7-1.8-1.62.0-1.8-2.32.1-2.2-1.4-1.1-1.3-2.32.1-2.3-1.7-2.42.4-2.0-2.1-2.4
Food seeking constrained by brief footshock4.75.712.0-2.3-1.52.7-1.9-3.32.4-2.3-1.4-0.5-1.2-3.02.3-3.1-1.5-3.03.0-2.1-2.2-3.5
Seeking ratio, punishment vs. effort0.00.00.20.30.20.10.30.1-0.10.20.20.20.20.2-0.10.20.40.1-0.10.30.40.0
Run reversals in cocaine runway, females0.30.30.8-0.9-0.40.5-0.6-0.80.10.2-0.2-0.0-0.2-0.40.1-0.5-0.5-0.50.5-0.3-0.8-0.9
Run reversals in cocaine runway, males2.12.03.9-1.2-2.00.5-1.5-1.11.7-1.8-1.5-1.7-1.3-0.91.5-0.9-1.6-1.31.3-1.6-1.6-0.9
Latency to leave start box in cocaine runway1.01.04.0-1.8-0.00.4-0.9-1.80.3-0.5-0.60.9-0.1-2.00.1-1.9-0.0-0.70.7-0.7-1.0-0.9
Latency to leave start box in cocaine runway, F0.20.20.9-0.80.4-0.3-0.2-0.8-0.2-0.0-0.10.80.3-1.0-0.4-0.80.30.0-0.1-0.1-0.30.1
Latency to leave start box in cocaine runway, M1.21.13.1-1.8-0.60.6-1.1-1.60.7-0.6-0.80.1-0.6-1.70.6-1.7-0.5-0.90.9-1.0-1.2-1.1
Cd content in liver0.50.52.41.10.51.50.8-0.20.5-1.00.90.51.1-0.10.5-0.20.5-0.70.70.40.5-0.5
Co content in liver0.10.20.70.7-0.20.30.30.80.1-0.1-0.0-0.70.10.60.20.8-0.20.1-0.10.10.30.5
Cu content in liver0.00.10.3-0.30.0-0.5-0.10.3-0.30.3-0.10.00.1-0.0-0.20.40.10.3-0.3-0.0-0.10.2
Fe content in liver0.10.10.60.30.10.30.30.3-0.30.50.00.20.30.8-0.30.40.20.2-0.20.40.1-0.1
K content in liver0.10.10.6-0.7-0.30.1-0.4-0.10.0-0.0-0.2-0.2-0.1-0.1-0.1-0.1-0.30.0-0.1-0.3-0.8-0.3
Mg content in liver0.60.62.4-1.5-0.9-0.1-1.2-0.50.3-0.1-0.8-0.7-0.8-0.70.2-0.5-1.0-0.20.2-1.0-1.6-0.5
Mn content in liver0.10.10.30.2-0.4-0.4-0.10.40.2-0.3-0.3-0.6-0.10.5-0.00.5-0.30.3-0.3-0.1-0.10.5
Na content in liver0.50.62.3-0.8-0.1-1.5-0.40.5-0.91.1-0.40.0-0.30.5-1.10.5-0.11.1-1.10.2-0.50.6
Rb content in liver1.21.52.7-1.6-1.00.8-1.4-1.31.0-1.0-1.1-0.6-1.1-1.51.0-1.3-1.1-1.21.2-1.3-1.6-1.6
Se content in liver0.20.31.2-0.5-0.30.8-0.5-0.40.3-0.2-0.5-0.2-0.4-0.40.3-0.5-0.4-0.50.5-0.4-1.0-1.1
Sr content in liver7.46.88.3-2.3-2.91.9-2.6-2.52.9-2.7-2.7-2.4-2.7-2.42.7-2.5-2.8-2.72.7-2.8-2.7-2.3
Zn content in liver1.41.63.4-1.0-1.50.5-1.4-0.61.3-1.0-1.7-1.8-1.7-0.61.3-0.5-1.5-0.80.7-1.6-1.8-0.6