Hub : Genes

Pls1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000009945 0.04 0.03 1.3e-04 0.01 0.03 0.02 0.03 3.1e-02 2.1e-04 1.0e-03 6.3e-04
2 BLA gene expression ENSRNOG00000009945 0.07 0.04 1.1e-03 0.07 0.07 0.07 0.07 9.8e-05 2.1e-04 1.8e-04 8.5e-05
3 Brain gene expression ENSRNOG00000009945 0.26 0.1 0.0e+00 0.25 0.29 0.29 0.28 2.4e-23 2.7e-27 1.2e-26 4.2e-26
4 Brain mRNA stability ENSRNOG00000009945 0.18 0.09 1.8e-12 0.15 0.13 0.13 0.14 7.8e-14 4.0e-12 4.8e-12 2.5e-13
5 Liver gene expression ENSRNOG00000009945 0.36 0.1 0.0e+00 0.42 0.43 0.42 0.43 5.0e-51 2.2e-51 2.7e-50 1.9e-51
6 Liver mRNA stability ENSRNOG00000009945 0.02 0.02 7.3e-03 0.01 0.02 0.01 0.01 7.3e-03 4.4e-03 4.8e-02 1.3e-02
7 NAcc gene expression ENSRNOG00000009945 0.22 0.09 5.6e-17 0.2 0.24 0.24 0.24 2.9e-15 1.1e-17 6.2e-18 3.5e-18
8 NAcc mRNA stability ENSRNOG00000009945 0.07 0.05 1.5e-04 0.05 0.04 0.05 0.05 2.2e-04 6.3e-04 1.2e-04 1.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail5.417.632.20.6-4.5-2.1-5.7-4.2-5.6-2.5-5.4
BMI without tail3.57.323.82.9-2.00.2-3.3-2.0-4.9-0.1-2.7
Body weight3.816.231.30.4-4.0-1.8-5.5-4.0-5.6-1.9-5.4
Epididymis fat weight0.81.84.60.8-1.1-0.2-1.9-1.3-2.1-0.3-1.7
Glucose0.30.50.7-0.2-0.8-0.8-0.6-0.8-0.3-0.8-0.8
Heart weight0.60.82.0-1.0-0.7-0.5-0.9-1.1-0.8-0.4-1.4
Left kidney weight3.29.113.3-0.2-3.6-1.8-3.6-3.6-3.6-2.2-3.6
Right kidney weight3.29.114.2-0.2-3.8-1.7-3.5-3.6-3.5-2.4-3.6
Tail length0.92.76.92.61.02.0-0.10.7-2.12.10.1
Length with tail0.10.41.20.0-0.10.2-0.8-0.2-1.10.6-0.9
Length without tail1.43.07.2-2.7-1.4-1.9-1.7-1.3-0.0-1.4-2.2
Liver weight, left0.10.20.60.4-0.8-0.1-0.1-0.5-0.5-0.4-0.3
Liver weight, right1.83.05.60.0-2.4-1.5-1.7-2.2-1.6-1.8-1.6
Parametrial fat weight0.10.30.70.20.30.20.80.30.7-0.00.9
Retroperitoneal fat weight0.72.48.01.3-1.30.2-1.8-1.4-2.8-0.1-1.7
Intraocular pressure0.50.81.50.1-0.7-0.6-1.2-1.0-1.1-0.5-1.1
Extensor digitorum longus weight2.510.115.0-1.1-3.8-2.9-3.6-3.9-2.5-3.1-3.6
Soleus weight1.13.15.70.2-2.0-1.1-2.4-2.0-2.1-1.4-2.1
Tibialis anterior weight1.03.36.50.2-2.0-0.8-2.2-1.9-2.5-0.9-2.5
Tibia length0.30.83.00.6-0.60.2-1.0-0.5-1.70.3-1.2
Number of licking bursts0.10.20.5-0.20.20.10.70.30.60.30.4
Food consumed during 24 hour testing period0.50.61.30.10.90.51.20.90.80.80.7
Times rat made contact with spout1.31.53.7-1.9-1.1-1.6-0.4-0.90.8-1.4-0.7
Mean time between licks in bursts0.71.02.9-1.7-0.8-1.2-0.7-0.80.6-1.0-0.6
Mean num. licks in bursts1.11.31.9-1.2-1.2-1.3-1.3-1.1-0.2-1.4-1.2
Std. dev. time between licks in bursts0.10.10.3-0.30.3-0.4-0.0-0.10.6-0.20.4
Water consumed over 24 hours0.20.20.4-0.40.4-0.10.50.50.70.30.2
Indifference point 0 sec0.10.10.40.5-0.40.3-0.2-0.2-0.60.0-0.2
Indifference point AUC0.10.10.40.60.20.5-0.40.0-0.40.20.1
Indifference point function ln k0.00.10.2-0.20.2-0.00.10.3-0.10.5-0.2
Indifference point function log k0.00.10.2-0.20.2-0.00.10.3-0.10.5-0.2
Delay discounting total patch changes 0 sec0.20.20.50.1-0.6-0.1-0.6-0.6-0.7-0.3-0.5
Delay discounting total patch changes 12 sec0.30.41.0-0.2-0.7-0.4-1.0-0.8-0.5-0.6-0.6
Delay discounting total patch changes 18 sec0.10.20.50.50.10.4-0.4-0.0-0.70.4-0.6
Delay discounting total patch changes 24 sec0.10.10.40.20.60.30.00.20.00.50.1
Delay discounting total patch changes 6 sec0.10.10.40.7-0.10.5-0.00.1-0.3-0.00.4
Delay discounting time to switch 0 sec1.31.94.00.51.41.02.01.51.41.01.7
Delay discounting water rate 0 sec0.61.02.70.4-0.9-0.3-1.5-0.8-1.6-0.3-1.2
Delay discounting water rate 12 sec0.60.91.6-0.4-0.9-0.9-1.3-1.0-0.9-0.6-1.3
Delay discounting water rate 18 sec2.33.04.7-0.1-2.0-1.1-2.1-1.9-2.1-1.3-2.2
Delay discounting water rate 24 sec0.20.30.7-0.0-0.2-0.1-0.8-0.4-0.8-0.1-0.7
Delay discounting water rate 6 sec0.81.22.2-0.6-1.2-1.2-1.2-1.1-0.9-0.9-1.5
Locomotor activity1.01.66.11.6-0.11.0-1.0-0.2-2.50.9-1.3
Locomotor testing distance0.40.72.61.20.20.5-0.7-0.1-1.60.7-0.8
Locomotor testing rearing0.50.82.40.9-0.5-0.2-1.0-1.0-1.6-0.3-0.8
Light reinforcement 10.10.10.3-0.3-0.3-0.40.10.00.4-0.50.2
Light reinforcement 20.40.51.2-1.1-0.6-0.9-0.1-0.20.7-0.8-0.4
Reaction time number correct0.20.31.01.0-0.30.60.00.0-0.80.10.2
Reaction time mean minus median0.60.72.3-0.3-1.5-0.6-0.3-1.1-0.5-1.0-0.6
Reaction time mean minus median AUC0.91.12.8-0.2-1.7-0.9-0.6-1.5-0.7-1.2-0.9
Reaction time num false alarms0.71.02.10.51.01.01.11.50.61.10.8
Reaction time num false alarms AUC1.01.42.50.41.11.11.51.61.11.11.2
Reaction time trials correct on left0.20.31.01.0-0.30.60.00.0-0.80.10.2
Reaction time trials on left0.20.31.01.0-0.40.60.00.0-0.80.10.2
Reaction time mean0.50.71.7-1.3-0.7-0.90.1-0.61.0-0.90.0
Reaction time mean AUC0.30.41.2-1.0-0.3-0.50.4-0.11.1-0.60.4
Median of all reaction times0.50.72.4-1.3-0.1-0.70.5-0.01.6-0.60.5
Reaction time omissions0.10.10.20.4-0.00.40.30.1-0.20.20.2
Reaction time false alarm rate0.71.01.8-0.11.10.61.21.31.20.90.8
Reaction time premature initiation rate0.30.41.1-0.4-0.0-0.40.70.31.0-0.41.1
Reaction time premature initiations0.10.20.80.2-0.3-0.10.60.10.4-0.40.9
Std. dev. reaction times0.20.20.7-0.5-0.9-0.50.1-0.60.2-0.6-0.1
Reaction time trials completed0.20.31.01.0-0.40.60.00.0-0.80.10.2
Reaction time trials AUC0.20.20.80.9-0.30.60.20.1-0.60.20.3
Social response proportion0.30.30.8-0.60.30.30.80.40.9-0.00.5
Social responses0.30.41.3-1.0-0.1-0.60.4-0.11.2-0.70.2
Social time0.50.61.8-1.3-0.1-0.50.8-0.11.3-0.50.5
Conditioned locomotion0.91.02.61.60.81.40.70.8-0.41.01.0
Cocaine response after cond. corrected0.20.20.80.8-0.40.1-0.2-0.4-0.9-0.0-0.2
Cocaine response after cond. not corrected0.40.51.71.1-0.50.2-0.3-0.4-1.30.1-0.4
Cocaine response before conditioning0.10.20.50.7-0.00.4-0.00.0-0.70.4-0.1
Saline control response1.62.13.4-0.1-1.5-0.8-1.8-1.8-1.8-0.9-1.8
Condit. Reinf. active minus inactive responses0.20.30.90.31.00.40.30.60.10.9-0.0
Condit. Reinf. active-inactive response ratio0.60.61.90.90.20.4-0.6-0.2-1.40.7-1.0
Condit. Reinf. active responses0.60.81.7-0.01.30.31.00.91.10.80.8
Condit. Reinf. inactive responses0.91.12.9-0.41.00.01.21.01.70.31.3
Condit. Reinf. lever presses0.20.30.9-1.00.4-0.50.30.20.9-0.0-0.2
Condit. Reinf. lever reinforcers received0.40.61.4-0.31.20.10.80.81.10.70.5
Pavlov. Cond. lever latency0.30.41.50.40.30.51.00.50.60.21.2
Pavlov. Cond. magazine entry latency1.41.62.2-1.4-1.3-1.4-1.3-1.4-0.3-1.2-1.5
Pavlov. Cond. change in total contacts1.11.53.3-0.0-0.9-0.8-1.8-1.2-1.5-0.4-1.8
Pavlov. Cond. index score0.40.51.4-0.9-0.4-0.7-0.9-0.6-0.3-0.4-1.2
Pavlov. Cond. latency score0.50.61.5-0.9-0.6-0.8-1.0-0.8-0.4-0.5-1.2
Pavlov. Cond. lever contacts0.50.61.5-0.9-0.6-0.9-0.9-0.7-0.3-0.5-1.2
Pavlov. Cond. magazine entry number0.91.12.21.50.91.30.91.0-0.31.11.0
Pavlov. Cond. intertrial magazine entries4.15.37.41.12.72.12.62.71.82.22.7
Pavlov. Cond. lever-magazine prob. diff.0.60.81.8-1.0-0.7-0.9-1.1-0.8-0.3-0.6-1.3
Pavlov. Cond. response bias0.70.91.6-1.1-0.7-1.2-0.9-0.90.0-0.8-1.3
Conditioned reinforcement - actives0.00.00.10.10.10.00.10.0-0.0-0.20.1
Conditioned reinforcement - inactives0.10.10.20.4-0.5-0.20.1-0.2-0.2-0.40.1
Conditioned locomotion0.30.30.6-0.3-0.8-0.5-0.4-0.7-0.3-0.7-0.5
Intermittent access intake day 1-15 change0.10.10.10.10.1-0.0-0.4-0.2-0.4-0.0-0.4
Intermittent access intake escalation0.10.10.3-0.0-0.1-0.2-0.5-0.3-0.4-0.3-0.4
Intermittent access intake escalation 20.20.20.8-0.50.3-0.10.60.40.9-0.20.4
Intermitt. access day 1 inactive lever presses0.70.82.00.0-1.4-0.4-0.7-1.2-0.9-1.0-0.6
Intermitt. access day 15 inactive lever presses1.01.12.5-1.4-1.3-1.3-0.3-0.80.7-1.6-0.4
Intermitt. access escalation Index0.40.30.90.90.40.50.60.6-0.20.40.6
Intermittent access day 1 total infusions0.20.20.6-0.1-0.8-0.4-0.2-0.7-0.4-0.6-0.3
Intermittent access day 15 total infusions0.30.40.60.0-0.7-0.6-0.6-0.7-0.6-0.8-0.5
Intermittent access terminal intake (last 3 days)0.50.61.1-0.5-0.9-0.9-0.5-0.8-0.3-1.0-0.7
Intermittent access total infusions0.30.30.7-0.3-0.7-0.6-0.3-0.8-0.2-0.7-0.4
Intermittent access day 1 locomotion0.30.31.10.1-1.0-0.1-0.2-0.8-0.7-0.6-0.3
Intermittent access day 15 total locomotion0.40.40.9-0.4-1.0-0.7-0.2-0.8-0.1-0.9-0.4
Intermittent access total locomotion0.40.41.1-0.1-1.0-0.3-0.2-1.0-0.5-0.9-0.3
Intermittent access standard deviation1.01.02.1-1.4-0.9-1.4-0.4-0.50.9-1.5-0.3
Cocaine induced anxiety0.70.82.9-1.50.3-0.60.70.01.7-0.60.5
Post-drug Anxiety0.70.72.6-1.60.1-1.00.1-0.41.3-0.6-0.0
Baseline Anxiety0.20.20.5-0.0-0.1-0.3-0.7-0.4-0.50.1-0.7
Lifetime Intake0.20.20.5-0.2-0.5-0.5-0.2-0.7-0.2-0.5-0.4
Incentive Sensitization - Responses1.21.13.1-1.5-0.3-1.7-0.8-0.80.8-1.2-0.8
Incentive Sensitization - Breakpoint1.21.23.0-1.5-0.3-1.7-0.7-0.80.7-1.3-0.9
Progressive ratio test 1 active lever presses0.10.10.60.5-0.10.3-0.1-0.3-0.7-0.0-0.1
Progressive ratio test 1 breakpoint0.30.31.00.4-0.30.1-0.4-0.7-1.0-0.2-0.5
Progressive ratio test 1 inactive lever presses0.10.10.50.4-0.20.6-0.0-0.2-0.70.1-0.0
Progressive ratio test 2 active lever presses0.30.30.6-0.5-0.3-0.7-0.7-0.6-0.3-0.6-0.8
Progressive ratio test 2 breakpoint0.10.10.2-0.20.1-0.3-0.4-0.4-0.3-0.2-0.5
Progressive ratio test 2 inactive lever presses0.10.10.30.00.40.30.50.30.30.00.5
Total sessions with >9 infusions0.10.10.30.3-0.20.2-0.1-0.2-0.50.0-0.2
Short access day 1 total inactive lever presses0.20.30.80.9-0.30.50.6-0.1-0.2-0.20.7
Short access day 10 total inactive lever presses1.21.33.0-0.7-1.5-1.1-0.8-1.3-0.1-1.7-0.7
Short access day 1 total infusions0.10.10.40.7-0.40.10.4-0.3-0.4-0.20.3
Short access day 10 total infusions0.40.40.90.0-0.7-0.4-0.7-0.9-0.9-0.5-0.8
Short access total infusions0.10.10.30.4-0.3-0.00.0-0.5-0.5-0.1-0.1
Short access day 1 locomotion1.21.24.62.10.61.30.10.1-1.41.00.5
Short access day 10 total locomotion1.21.43.0-0.7-1.7-0.7-0.8-1.6-0.6-1.6-0.9
Short access total locomotion0.70.72.50.8-0.60.4-0.8-1.0-1.6-0.1-0.7
Compulsive drug intake3.63.65.42.12.12.31.42.1-0.02.31.8
One hour access (0.3 mA shock)0.40.50.70.50.90.60.70.70.30.80.7
One hour access (shock baseline)0.50.61.8-1.3-0.2-1.10.1-0.41.0-0.8-0.2
Number of responses in last shaping day0.50.51.71.1-0.50.6-0.3-0.4-1.3-0.1-0.2
Context. condit. distance diff. score0.81.02.5-1.6-0.6-1.4-0.2-0.71.1-1.2-0.4
Locomotion velocity, session 11.81.93.10.5-1.6-0.9-1.6-1.6-1.8-1.0-1.6
Locomotion distance, session 13.85.07.40.2-2.6-1.7-2.7-2.7-2.4-1.8-2.6
Locomotion velocity, session 24.85.68.7-0.4-2.8-2.1-2.7-3.0-2.0-2.2-2.8
Locomotion distance, session 25.07.110.90.1-3.0-2.1-3.3-3.2-2.8-2.2-3.1
Locomotion velocity, session 30.80.92.2-0.6-1.0-1.5-0.5-1.20.4-1.4-0.4
Locomotion distance, session 30.30.30.8-0.9-0.0-0.8-0.2-0.50.7-0.5-0.1
Stereotopy head waving bouts, day 30.10.10.3-0.5-0.3-0.40.20.40.6-0.20.3
Stereotopy head waving duration, day 30.20.20.60.3-0.8-0.3-0.6-0.2-0.6-0.3-0.2
Locomotion velocity, session 72.42.64.90.3-1.6-1.2-2.2-1.9-1.9-1.2-1.8
Locomotion distance, session 70.30.41.50.7-0.10.2-0.9-0.5-1.20.3-0.6
Stereotopy head waving bouts, day 71.51.86.3-1.20.2-0.81.40.62.5-0.71.6
Stereotopy head waving duration, day 71.41.75.7-0.80.5-0.51.60.92.4-0.41.8
Locomotion velocity, session 82.32.85.1-0.3-2.1-1.8-1.6-2.3-0.9-1.9-1.5
Locomotion distance, session 82.23.35.2-1.0-2.1-2.1-1.8-2.3-0.7-2.0-1.8
Degree of sensitization distance0.70.72.41.3-0.00.8-0.60.1-1.50.7-0.5
Degree of sensitization stereotypy1.71.85.4-1.9-0.4-1.50.8-0.32.3-1.40.7
Condit. Reinf. active minus inactive responses0.10.20.5-0.7-0.0-0.4-0.4-0.20.0-0.0-0.6
Condit. Reinf. active-inactive response ratio2.22.34.6-1.0-1.6-1.4-1.9-1.6-1.3-1.0-2.1
Condit. Reinf. active responses0.00.00.2-0.10.40.00.10.20.20.3-0.1
Condit. Reinf. inactive responses1.61.93.01.01.71.21.51.51.01.21.6
Incentive salience index mean0.70.91.6-1.2-0.7-1.1-1.0-0.9-0.1-0.7-1.3
Condit. Reinf. lever presses1.82.53.6-0.8-1.8-1.5-1.9-1.8-1.1-1.5-1.9
Time in familiar zone, hab. session 15.24.97.81.42.62.42.12.81.02.42.4
Time in novel zone, hab. session 13.73.65.8-1.2-2.1-1.8-2.0-2.4-1.2-1.7-2.3
Total zone transitions, hab. session 12.94.17.00.3-2.3-1.6-2.7-2.4-2.1-1.8-2.1
Total locomotion distance, hab. session 12.02.86.41.1-1.7-0.5-2.3-1.7-2.5-0.9-1.7
Locomotion velocity, hab. session 12.33.36.61.1-1.9-0.8-2.5-1.9-2.6-1.2-1.8
Time in familiar zone, hab. session 20.50.50.90.30.90.60.70.90.30.80.8
Time in novel zone, hab. session 21.91.93.1-0.8-1.8-1.2-1.4-1.7-0.9-1.3-1.6
Total zone transitions, hab. session 23.03.96.30.2-2.2-1.6-2.5-2.3-2.1-1.6-2.3
Total locomotion distance, hab. session 21.82.36.21.3-1.4-0.4-2.0-1.4-2.5-0.6-1.6
Locomotion velocity, hab. session 21.72.36.01.3-1.4-0.4-2.0-1.4-2.4-0.6-1.6
Novel to familiar place preference ratio0.10.10.20.0-0.30.2-0.40.0-0.40.1-0.5
Novelty place preference0.20.20.5-0.1-0.50.1-0.6-0.2-0.60.0-0.7
Time in novel zone, NPP test0.40.41.1-0.3-0.7-0.1-0.9-0.5-0.8-0.1-1.1
Total zone transitions, NPP test7.110.115.40.1-3.7-2.2-3.9-3.7-3.5-2.5-3.8
Total locomotion distance, NPP test4.46.112.01.1-2.7-1.2-3.2-2.5-3.5-1.5-2.8
Locomotion velocity, NPP test3.24.69.51.2-2.3-0.9-2.8-2.2-3.1-1.3-2.3
Pavlov. Cond. lever latency1.01.31.81.01.11.31.31.30.41.21.3
Pavlov. Cond. magazine entry latency2.22.94.4-2.0-1.6-2.1-1.7-1.9-0.2-1.9-1.5
Pavlov. Cond. change in total contacts1.11.12.1-1.4-1.0-1.4-0.7-1.00.4-1.4-0.8
Pavlov. Cond. index score1.72.23.0-1.6-1.3-1.7-1.6-1.7-0.3-1.5-1.5
Pavlov. Cond. latency score1.72.23.0-1.4-1.3-1.6-1.7-1.7-0.6-1.4-1.7
Pavlov. Cond. lever contacts1.21.41.9-1.1-1.1-1.3-1.4-1.3-0.4-1.2-1.4
Pavlov. Cond. magazine entry number1.31.63.31.80.91.61.11.3-0.21.31.1
Pavlov. Cond. intertrial magazine entries2.73.25.30.32.31.32.22.11.71.71.9
Pavlov. Cond. lever-magazine prob. diff.1.72.13.1-1.7-1.3-1.8-1.3-1.6-0.0-1.6-1.3
Pavlov. Cond. response bias1.11.33.4-1.8-0.8-1.6-0.6-1.00.7-1.4-0.7
Bone: apparent density0.61.02.1-0.41.50.41.11.11.20.81.0
Bone surface1.01.84.6-0.91.40.11.71.32.10.51.5
Bone volume0.61.12.2-0.51.30.21.31.01.50.61.1
Bone: connectivity density0.91.42.7-0.21.40.61.51.21.50.71.6
Bone: cortical apparent density0.10.20.60.6-0.20.80.2-0.2-0.40.10.2
Bone: cortical area2.64.05.8-1.8-2.2-2.4-1.9-2.4-0.4-2.3-1.9
Bone: cortical porosity1.01.12.0-1.2-0.7-1.4-1.0-1.10.1-1.0-1.2
Bone: cortical porosity1.21.32.3-1.3-0.9-1.5-1.1-1.20.2-1.2-1.2
Bone: cortical thickness1.42.23.5-1.3-1.8-1.6-1.4-1.9-0.3-1.8-1.2
Bone: cortical thickness0.10.10.4-0.40.2-0.2-0.5-0.2-0.1-0.0-0.7
Bone: cortical tissue density0.10.20.60.6-0.20.80.2-0.2-0.40.10.2
Bone: elastic displacement2.12.44.4-0.7-1.6-1.1-2.1-1.7-1.5-1.2-2.0
Bone: elastic work1.01.42.7-0.7-0.9-1.0-1.6-1.4-1.0-0.8-1.6
Bone: endosteal estimation0.40.81.5-0.4-0.7-1.2-1.0-1.0-0.5-0.8-1.2
Bone: endosteal perimeter1.73.65.1-1.5-2.0-2.3-1.8-2.2-0.7-2.0-2.1
Bone: final force0.10.20.5-0.50.3-0.7-0.5-0.50.1-0.1-0.4
Bone: final moment0.10.20.4-0.50.3-0.6-0.6-0.5-0.2-0.0-0.6
Bone: marrow area0.51.01.8-0.4-0.8-1.2-1.1-1.2-0.6-0.9-1.3
Bone: maximum diameter4.07.310.7-1.5-3.2-2.9-2.8-3.3-1.5-2.9-2.7
Bone: maximum force0.30.51.0-1.0-0.2-1.0-0.4-1.00.2-0.6-0.6
Bone: maximum moment0.30.61.1-0.9-0.3-1.0-0.7-1.1-0.1-0.6-0.9
Bone: minimum diameter0.40.82.4-1.6-0.2-1.3-0.6-0.70.7-0.7-0.6
Bone: periosteal estimation1.53.04.7-1.3-1.7-2.2-1.8-2.1-0.6-1.8-1.9
Bone: periosteal perimeter2.94.77.4-2.0-2.2-2.7-2.0-2.7-0.5-2.4-2.1
Bone: post-yield work0.40.51.7-1.10.3-0.60.7-0.11.3-0.20.2
Bone: stiffness0.50.81.9-1.4-0.0-1.10.6-0.51.4-0.70.2
Bone: tissue strength0.10.10.20.3-0.20.30.10.1-0.40.1-0.1
Bone: trabecular number1.01.63.6-0.71.60.31.41.31.90.81.4
Bone: trabecular spacing0.30.41.41.2-0.20.6-0.4-0.1-1.10.3-0.2
Bone: trabecular thickness0.60.82.01.30.60.7-0.60.1-1.41.0-0.4
Bone: trabecular tissue density1.01.43.30.5-1.2-0.3-1.4-1.3-1.8-0.4-1.4
Breakpoint value in progressive ratio session0.70.71.5-0.61.00.41.20.61.20.41.1
Distance traveled before self-admin1.81.93.2-0.1-1.4-0.9-1.6-1.8-1.5-1.1-1.7
Distance traveled after self-admin0.10.10.30.10.20.6-0.2-0.1-0.60.3-0.2
Delta time in closed arm before/after self-admin1.11.13.0-1.7-0.4-1.20.2-0.51.7-1.10.2
Delta time in open arm before/after self-admin0.90.81.91.40.81.10.60.5-0.41.01.2
Diff in mean of infusions in LGA sessions0.40.51.5-0.80.4-0.40.70.51.2-0.10.6
Extinction: sum of active levers before priming0.10.10.4-0.30.10.2-0.6-0.3-0.40.2-0.4
Active lever presses in extinction session 60.10.10.20.10.10.2-0.3-0.4-0.50.2-0.3
Delta distance traveled before/after self-admin1.51.62.50.41.61.51.11.50.71.41.5
Delta ambulatory time before/after self-admin1.21.32.20.81.11.50.91.40.31.21.3
Time in closed arm before self-admin1.72.05.52.30.61.6-0.10.6-2.11.6-0.2
Time in closed arm after self-admin0.30.30.80.3-0.8-0.1-0.6-0.6-0.9-0.3-0.7
Time in open arm before self-admin0.50.51.8-1.30.2-0.50.20.41.3-0.40.2
Time in open arm after self-admin1.21.33.00.01.30.81.31.11.30.81.7
Sum of active levers in priming session hrs 5-61.01.01.8-0.9-0.9-1.0-1.1-1.3-0.6-0.8-1.2
Time to tail flick, vehicle, before self-admin0.10.10.30.60.20.0-0.10.0-0.20.00.2
Time to tail flick, vehicle, after self-admin0.50.51.60.5-0.7-0.1-1.0-0.7-1.3-0.2-0.8
Time to tail flick, test, before self-admin0.30.31.0-0.3-0.0-0.20.90.51.0-0.30.7
Time to tail flick, test, after self-admin0.20.20.70.1-0.4-0.1-0.8-0.2-0.8-0.0-0.6
Delta time to tail flick, vehicle, before/after SA0.40.40.90.1-0.6-0.1-0.6-0.7-0.9-0.1-0.8
Delta time to tail flick, test, before/after SA0.60.62.01.00.10.7-0.70.0-1.40.7-0.4
Ambulatory time before self-admin1.81.83.0-0.3-1.5-1.0-1.5-1.7-1.4-1.2-1.7
Ambulatory time after self-admin0.20.20.60.40.00.7-0.2-0.1-0.80.3-0.2
Total heroin consumption0.80.94.4-2.1-0.0-1.2-0.1-0.41.2-0.4-0.3
Area under the delay curve0.40.41.6-0.50.4-0.20.70.71.2-0.10.6
Delay disc. indifference point, 0s delay1.41.53.2-0.31.40.41.51.31.80.61.6
Delay disc. indifference point, 16s delay0.30.30.6-0.8-0.4-0.8-0.4-0.30.3-0.6-0.6
Delay disc. indifference point, 2s delay0.30.40.9-0.5-0.7-0.9-0.4-0.30.2-0.8-0.6
Delay disc. indifference point, 24s delay0.10.10.3-0.30.20.10.20.20.50.10.1
Delay disc. indifference point, 4s delay1.11.22.50.70.80.51.61.21.20.41.5
Delay disc. indifference point, 8s delay0.50.51.7-1.00.5-0.20.60.61.30.00.4
Delay discount exponential model param0.30.31.10.3-0.40.0-0.7-0.7-1.0-0.0-0.6
Delay discount hyperbolic model param0.30.31.00.3-0.20.2-0.6-0.6-1.00.1-0.5
Fecal boli incidents, locomotor time 10.80.91.40.2-1.2-0.9-1.1-0.9-0.9-0.9-1.1
Change in fecal boli incidents, locomotor task0.50.51.70.8-0.20.4-0.9-0.2-1.30.3-0.5
Time >=10cm from walls, locomotor time 10.40.40.8-0.5-0.6-0.7-0.6-0.9-0.2-0.6-0.7
Bouts of movement, locomotor time 10.00.00.0-0.2-0.0-0.00.10.10.1-0.0-0.0
Total resting periods, locomotor time 10.10.10.1-0.3-0.4-0.3-0.1-0.20.1-0.3-0.2
Rest time, locomotor task time 13.64.06.5-2.3-2.0-2.5-1.6-2.10.3-2.4-1.7
Distance moved, locomotor task time 11.21.33.11.81.01.50.71.1-0.61.40.8
Vertical activity count, locomotor time 10.80.81.60.21.00.81.31.00.90.71.1
Time >=10cm from walls, locomotor time 20.90.92.6-1.6-0.1-1.20.4-0.41.6-0.90.2
Bouts of movement, locomotor time 20.50.50.9-0.4-0.8-0.6-0.9-0.9-0.4-0.7-0.6
Total resting periods, locomotor time 20.60.60.9-0.7-0.9-0.7-0.9-0.9-0.3-0.9-0.7
Rest time, locomotor task time 20.20.20.4-0.5-0.6-0.3-0.2-0.5-0.0-0.5-0.4
Distance moved, locomotor task time 20.60.71.6-0.01.00.00.90.81.30.41.0
Vertical activity count, locomotor time 20.70.82.5-0.80.8-0.21.00.71.60.10.9
Weight adjusted by age1.41.64.5-0.1-0.6-0.2-2.1-1.2-2.0-0.2-1.5
Seeking ratio, delayed vs. immediate footshock0.20.21.0-0.40.4-0.10.40.21.0-0.10.6
Locomotion in novel chamber0.70.92.00.00.70.51.41.11.30.31.2
Locomotion in novel chamber post-restriction0.60.81.60.80.70.91.11.30.30.90.7
Progressive ratio1.41.63.0-0.4-1.2-1.2-1.7-1.3-1.2-0.9-1.7
Food seeking constrained by brief footshock1.01.22.3-1.4-1.0-1.5-0.1-1.20.9-1.5-0.3
Seeking ratio, punishment vs. effort0.60.72.1-0.70.1-0.31.20.21.5-0.51.1
Run reversals in cocaine runway, females1.11.12.91.70.91.30.00.4-1.21.30.3
Run reversals in cocaine runway, males2.72.65.7-2.4-1.6-2.1-0.6-1.41.1-2.1-0.8
Latency to leave start box in cocaine runway2.12.33.8-0.11.81.21.91.51.81.11.9
Latency to leave start box in cocaine runway, F1.82.03.31.11.81.71.21.50.41.61.4
Latency to leave start box in cocaine runway, M1.81.75.9-1.30.7-0.21.70.72.4-0.11.5
Cd content in liver1.31.43.7-1.9-0.6-1.30.6-0.11.9-1.30.4
Co content in liver0.60.71.3-1.0-0.9-1.1-0.4-0.90.3-1.1-0.5
Cu content in liver1.11.44.2-1.30.9-0.11.41.02.10.11.1
Fe content in liver0.60.72.0-1.00.9-0.20.90.81.40.40.5
K content in liver0.60.62.31.5-0.70.2-0.5-0.5-1.2-0.30.0
Mg content in liver0.20.20.60.8-0.40.0-0.4-0.4-0.6-0.30.0
Mn content in liver1.41.62.8-0.3-1.4-1.5-1.4-1.7-0.7-1.4-1.2
Na content in liver0.50.51.91.40.40.80.20.4-0.50.60.6
Rb content in liver0.10.20.40.60.50.4-0.00.3-0.40.60.1
Se content in liver1.11.32.60.71.31.01.11.60.81.11.3
Sr content in liver0.30.20.70.3-0.00.10.70.60.5-0.10.8
Zn content in liver0.10.10.20.50.20.20.20.0-0.10.20.2