Hub : Genes

Pnma2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000009815 0.35 0.15 1.1e-16 0.23 0.25 0.25 0.24 1.4e-12 1.4e-13 1.8e-13 4.8e-13
2 BLA isoform ratio ENSRNOT00000013001 0.12 0.08 4.6e-05 0.06 0.06 0.06 0.07 4.3e-04 2.6e-04 4.8e-04 1.7e-04
3 BLA isoform ratio ENSRNOT00000096509 0.12 0.08 5.3e-05 0.06 0.06 0.06 0.07 4.9e-04 3.1e-04 5.0e-04 2.1e-04
4 BLA intron excision ratio chr15:41112076:41116132 0.2 0.12 6.3e-08 0.11 0.12 0.1 0.12 2.1e-06 1.0e-06 4.2e-06 9.6e-07
5 BLA intron excision ratio chr15:41116260:41116539 0.08 0.06 2.0e-03 0.02 0.04 0.04 0.03 3.5e-02 4.7e-03 4.2e-03 1.3e-02
6 Brain gene expression ENSRNOG00000009815 0.51 0.17 0.0e+00 0.44 0.47 0.46 0.46 8.8e-45 5.0e-48 9.4e-48 1.3e-47
7 Brain intron excision ratio chr15:41112076:41116132 0.07 0.05 1.5e-05 0.02 0.05 0.03 0.04 4.3e-03 1.4e-05 7.7e-04 3.4e-04
8 IL gene expression ENSRNOG00000009815 0.32 0.17 1.9e-04 0.16 0.16 0.15 0.15 9.2e-05 1.4e-04 1.9e-04 1.7e-04
9 LHb gene expression ENSRNOG00000009815 0.32 0.18 6.3e-04 0.08 0.09 0.12 0.1 6.7e-03 3.3e-03 9.5e-04 2.9e-03
10 OFC gene expression ENSRNOG00000009815 0.28 0.17 2.9e-03 0.04 0.06 0.03 0.06 4.1e-02 1.6e-02 7.8e-02 1.9e-02
11 PL gene expression ENSRNOG00000009815 0.4 0.15 0.0e+00 0.32 0.32 0.31 0.32 9.2e-25 1.2e-24 4.6e-24 2.0e-24
12 PL intron excision ratio chr15:41112076:41116132 0.07 0.05 6.3e-04 0.04 0.04 0.03 0.04 9.0e-04 4.8e-04 4.9e-03 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.72.32.51.6-1.61.61.6-1.51.51.51.61.51.51.31.5
BMI without tail0.10.30.70.30.0-0.0-0.00.70.60.70.20.90.7-0.10.8
Body weight0.00.10.2-0.10.0-0.00.0-0.5-0.3-0.40.0-0.4-0.4-0.2-0.4
Epididymis fat weight0.71.74.1-1.31.5-1.5-1.52.0-1.0-0.9-1.5-0.8-0.9-1.4-0.8
Glucose1.01.52.41.2-1.01.01.0-0.41.41.51.01.51.51.01.5
Heart weight0.71.01.2-1.01.0-1.0-1.01.0-1.0-0.9-1.0-0.8-0.9-1.1-0.9
Left kidney weight0.20.61.0-0.80.7-0.7-0.70.1-0.9-0.9-0.6-1.0-1.0-0.8-1.0
Right kidney weight3.08.59.3-3.02.9-2.9-2.92.2-3.0-3.0-2.9-3.1-3.0-3.0-3.0
Tail length1.95.66.5-2.42.5-2.5-2.52.5-2.3-2.2-2.4-2.1-2.2-2.5-2.2
Length with tail0.93.34.7-1.81.6-1.6-1.60.9-2.0-2.1-1.5-2.2-2.1-1.7-2.1
Length without tail0.20.53.20.2-0.70.70.7-1.8-0.3-0.50.5-0.7-0.50.5-0.6
Liver weight, left0.91.52.21.2-1.31.31.3-1.51.21.11.21.01.11.41.1
Liver weight, right1.22.02.51.4-1.61.61.6-1.61.31.31.51.21.21.41.2
Parametrial fat weight0.61.35.2-1.01.2-1.2-1.32.3-0.6-0.4-1.5-0.3-0.4-1.1-0.4
Retroperitoneal fat weight0.00.10.40.00.2-0.2-0.20.60.30.40.00.50.4-0.40.4
Intraocular pressure0.40.61.1-0.80.8-0.8-0.81.0-0.7-0.6-0.8-0.6-0.6-0.7-0.6
Extensor digitorum longus weight5.321.144.74.6-5.25.25.3-6.73.73.25.22.83.15.23.0
Soleus weight1.02.93.71.8-1.81.81.8-1.91.61.61.91.41.51.81.5
Tibialis anterior weight2.89.823.73.1-3.63.63.6-4.92.42.13.61.71.93.61.9
Tibia length5.214.615.6-3.93.8-3.8-3.83.1-3.9-3.9-3.8-3.9-3.9-3.9-3.9
Number of licking bursts0.70.81.00.9-1.01.01.0-0.30.90.90.71.01.00.71.0
Food consumed during 24 hour testing period1.92.32.9-1.61.6-1.6-1.61.3-1.5-1.5-1.5-1.4-1.5-1.7-1.5
Times rat made contact with spout0.20.20.7-0.30.5-0.5-0.50.8-0.1-0.1-0.40.1-0.0-0.6-0.0
Mean time between licks in bursts1.31.83.6-1.41.4-1.4-1.41.9-1.2-1.1-1.4-1.0-1.1-1.6-1.0
Mean num. licks in bursts0.81.01.5-1.01.2-1.2-1.20.8-0.9-0.9-1.0-0.8-0.9-1.0-0.9
Std. dev. time between licks in bursts6.07.27.5-2.72.7-2.7-2.72.6-2.7-2.7-2.7-2.7-2.7-2.6-2.7
Water consumed over 24 hours0.00.00.20.1-0.20.20.2-0.4-0.0-0.10.2-0.2-0.10.2-0.1
Indifference point 0 sec9.715.617.2-4.13.9-3.9-3.93.4-4.1-4.1-4.2-4.0-4.1-3.8-4.1
Indifference point AUC4.04.75.62.3-2.22.22.2-1.92.22.21.92.22.22.42.2
Indifference point function ln k1.82.63.1-1.71.5-1.5-1.51.3-1.7-1.7-1.6-1.7-1.7-1.8-1.7
Indifference point function log k1.82.63.1-1.71.5-1.5-1.51.3-1.7-1.7-1.6-1.7-1.7-1.8-1.7
Delay discounting total patch changes 0 sec9.014.615.8-3.93.7-3.7-3.73.3-4.0-4.0-4.0-3.9-4.0-3.7-4.0
Delay discounting total patch changes 12 sec1.51.92.3-1.41.4-1.4-1.41.1-1.5-1.5-1.5-1.5-1.5-1.1-1.5
Delay discounting total patch changes 18 sec1.11.42.3-1.21.3-1.3-1.31.4-1.1-1.0-1.5-1.0-1.0-1.0-1.0
Delay discounting total patch changes 24 sec2.53.13.9-1.81.7-1.7-1.71.1-1.9-2.0-1.7-2.0-2.0-1.6-2.0
Delay discounting total patch changes 6 sec0.71.01.8-1.00.9-0.9-0.91.1-1.0-1.0-1.3-0.9-1.0-0.9-1.0
Delay discounting time to switch 0 sec0.20.20.4-0.50.5-0.5-0.50.6-0.5-0.5-0.2-0.4-0.4-0.6-0.4
Delay discounting water rate 0 sec0.00.10.1-0.20.1-0.1-0.1-0.2-0.3-0.4-0.2-0.3-0.4-0.1-0.4
Delay discounting water rate 12 sec0.10.20.4-0.40.3-0.3-0.3-0.0-0.6-0.6-0.2-0.6-0.7-0.4-0.7
Delay discounting water rate 18 sec0.60.81.70.9-1.01.01.0-1.30.70.61.10.60.60.90.6
Delay discounting water rate 24 sec0.30.40.80.7-0.50.50.5-0.10.80.80.40.90.80.60.8
Delay discounting water rate 6 sec0.10.20.6-0.2-0.10.10.1-0.8-0.4-0.60.2-0.6-0.60.2-0.6
Locomotor activity3.14.98.6-2.21.8-1.8-1.80.1-2.6-2.8-1.4-2.9-2.9-1.8-2.9
Locomotor testing distance6.210.313.6-3.33.0-3.0-3.01.7-3.5-3.6-2.7-3.7-3.7-3.0-3.7
Locomotor testing rearing9.915.619.5-4.03.9-3.9-3.92.4-4.3-4.4-3.4-4.4-4.4-3.6-4.4
Light reinforcement 10.61.13.8-0.91.3-1.3-1.32.0-0.6-0.4-1.0-0.2-0.3-1.2-0.3
Light reinforcement 21.11.42.81.1-0.70.70.70.31.41.60.81.71.60.81.6
Reaction time number correct1.21.82.21.4-1.31.31.3-0.81.41.41.41.41.41.51.4
Reaction time mean minus median0.10.10.4-0.30.2-0.2-0.2-0.3-0.4-0.5-0.1-0.6-0.5-0.1-0.5
Reaction time mean minus median AUC0.00.00.1-0.10.1-0.1-0.1-0.3-0.2-0.20.2-0.3-0.2-0.1-0.2
Reaction time num false alarms0.40.60.7-0.80.8-0.8-0.80.5-0.8-0.8-0.6-0.8-0.8-0.7-0.8
Reaction time num false alarms AUC0.40.50.7-0.80.8-0.8-0.80.5-0.8-0.8-0.6-0.8-0.8-0.6-0.8
Reaction time trials correct on left1.21.82.21.4-1.31.31.3-0.81.41.41.41.41.41.51.4
Reaction time trials on left1.11.62.01.3-1.21.21.2-0.71.31.41.31.31.41.41.4
Reaction time mean0.00.00.10.0-0.10.10.1-0.4-0.1-0.1-0.0-0.2-0.10.1-0.2
Reaction time mean AUC0.00.10.3-0.0-0.10.10.1-0.5-0.2-0.20.0-0.3-0.30.1-0.3
Median of all reaction times0.00.00.10.1-0.20.20.2-0.20.00.0-0.0-0.00.00.2-0.0
Reaction time omissions0.60.81.8-0.91.0-1.0-1.01.3-0.7-0.6-0.9-0.6-0.6-0.9-0.6
Reaction time false alarm rate0.81.21.3-1.11.1-1.1-1.10.8-1.1-1.1-1.1-1.1-1.1-1.2-1.1
Reaction time premature initiation rate0.81.11.61.1-1.11.11.1-1.30.90.91.20.90.91.00.9
Reaction time premature initiations2.13.03.81.8-1.81.81.8-1.71.71.61.91.61.61.81.6
Std. dev. reaction times0.00.00.2-0.0-0.00.00.0-0.4-0.1-0.20.1-0.3-0.20.0-0.2
Reaction time trials completed1.11.62.01.3-1.21.21.2-0.71.31.41.31.31.41.41.4
Reaction time trials AUC1.01.52.01.3-1.21.21.2-0.71.31.31.21.31.31.41.3
Social response proportion2.72.94.21.7-1.51.51.6-1.01.91.91.62.12.01.32.0
Social responses0.60.82.8-0.81.1-1.1-1.11.7-0.4-0.2-1.0-0.0-0.2-1.2-0.2
Social time2.12.73.1-1.71.8-1.8-1.81.1-1.7-1.7-1.4-1.6-1.7-1.7-1.7
Conditioned locomotion0.80.91.21.0-0.90.90.9-0.61.11.10.91.01.11.01.1
Cocaine response after cond. corrected5.56.17.22.6-2.42.42.4-1.62.72.72.32.72.72.52.7
Cocaine response after cond. not corrected3.13.54.01.9-1.81.81.8-1.32.02.01.82.02.01.92.0
Cocaine response before conditioning3.54.35.0-2.12.1-2.1-2.11.2-2.2-2.2-1.9-2.2-2.2-2.0-2.2
Saline control response1.41.92.0-1.41.4-1.4-1.41.1-1.4-1.4-1.3-1.4-1.4-1.4-1.4
Condit. Reinf. active minus inactive responses0.30.40.4-0.60.6-0.6-0.70.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6
Condit. Reinf. active-inactive response ratio0.50.60.70.7-0.80.80.8-0.60.70.70.80.70.70.80.7
Condit. Reinf. active responses0.91.21.5-1.21.2-1.2-1.21.2-1.1-1.0-1.1-0.9-1.0-1.1-1.0
Condit. Reinf. inactive responses2.63.24.1-1.82.0-2.0-2.01.9-1.7-1.6-1.9-1.5-1.6-1.9-1.6
Condit. Reinf. lever presses2.02.83.5-1.71.6-1.6-1.61.0-1.8-1.9-1.5-1.9-1.9-1.7-1.9
Condit. Reinf. lever reinforcers received0.91.21.5-1.11.2-1.2-1.21.1-1.1-1.0-1.1-1.0-1.0-1.1-1.0
Pavlov. Cond. lever latency0.50.71.50.8-0.50.50.50.31.01.10.51.21.20.71.2
Pavlov. Cond. magazine entry latency1.61.82.1-1.41.3-1.3-1.30.8-1.4-1.5-1.2-1.4-1.5-1.4-1.5
Pavlov. Cond. change in total contacts0.20.30.8-0.2-0.10.10.1-0.9-0.5-0.70.1-0.8-0.7-0.1-0.7
Pavlov. Cond. index score0.91.22.1-1.00.8-0.8-0.8-0.1-1.3-1.4-0.7-1.4-1.4-1.0-1.4
Pavlov. Cond. latency score1.31.72.7-1.31.0-1.0-1.00.2-1.5-1.6-1.0-1.6-1.6-1.3-1.6
Pavlov. Cond. lever contacts1.21.63.0-1.20.9-0.9-0.9-0.0-1.5-1.6-0.9-1.7-1.7-1.1-1.7
Pavlov. Cond. magazine entry number1.41.72.31.3-1.21.21.2-0.81.41.41.21.31.41.51.4
Pavlov. Cond. intertrial magazine entries2.73.57.4-1.92.1-2.1-2.22.7-1.5-1.3-2.2-1.2-1.3-2.0-1.3
Pavlov. Cond. lever-magazine prob. diff.0.70.81.6-0.90.6-0.6-0.6-0.2-1.1-1.2-0.6-1.3-1.2-0.8-1.2
Pavlov. Cond. response bias1.21.73.1-1.30.9-0.9-0.9-0.1-1.5-1.7-0.9-1.8-1.7-1.1-1.7
Conditioned reinforcement - actives0.40.41.7-0.60.7-0.7-0.71.3-0.4-0.3-0.8-0.2-0.3-0.8-0.2
Conditioned reinforcement - inactives3.43.95.3-2.12.0-2.0-2.12.3-1.9-1.8-2.2-1.6-1.8-2.1-1.8
Conditioned locomotion0.20.20.8-0.50.5-0.5-0.50.9-0.3-0.2-0.6-0.1-0.2-0.5-0.2
Intermittent access intake day 1-15 change0.30.30.8-0.60.6-0.6-0.60.9-0.5-0.4-0.5-0.4-0.4-0.5-0.4
Intermittent access intake escalation0.00.00.1-0.20.3-0.3-0.30.3-0.1-0.0-0.0-0.0-0.0-0.2-0.0
Intermittent access intake escalation 20.10.10.1-0.20.3-0.3-0.30.2-0.2-0.1-0.2-0.1-0.1-0.2-0.1
Intermitt. access day 1 inactive lever presses0.20.20.30.4-0.40.40.4-0.20.50.50.40.50.50.30.5
Intermitt. access day 15 inactive lever presses0.00.00.0-0.10.1-0.1-0.10.1-0.1-0.1-0.0-0.1-0.1-0.1-0.1
Intermitt. access escalation Index0.40.30.50.6-0.60.60.6-0.70.50.50.70.50.50.60.5
Intermittent access day 1 total infusions0.00.00.00.1-0.00.00.00.20.10.1-0.20.20.20.00.2
Intermittent access day 15 total infusions0.10.10.20.2-0.10.10.10.30.40.40.10.50.40.20.5
Intermittent access terminal intake (last 3 days)0.40.50.70.7-0.60.60.6-0.20.80.80.50.80.80.70.8
Intermittent access total infusions0.20.20.50.4-0.30.30.30.30.60.60.20.70.70.30.7
Intermittent access day 1 locomotion1.31.31.5-1.21.2-1.2-1.21.1-1.1-1.1-1.2-1.0-1.1-1.2-1.1
Intermittent access day 15 total locomotion0.20.20.9-0.50.6-0.6-0.61.0-0.3-0.2-0.6-0.1-0.2-0.6-0.1
Intermittent access total locomotion0.60.70.9-0.90.8-0.8-0.80.9-0.8-0.8-0.9-0.7-0.7-0.8-0.7
Intermittent access standard deviation0.20.20.3-0.40.4-0.4-0.40.6-0.4-0.3-0.5-0.3-0.3-0.5-0.3
Cocaine induced anxiety1.31.42.5-1.20.9-0.9-0.90.3-1.4-1.5-1.0-1.6-1.5-0.9-1.6
Post-drug Anxiety1.61.72.2-1.31.4-1.4-1.41.5-1.3-1.2-1.5-1.1-1.2-1.4-1.2
Baseline Anxiety0.60.61.7-0.71.0-1.0-1.01.3-0.5-0.4-0.7-0.3-0.3-1.0-0.3
Lifetime Intake0.00.10.4-0.10.2-0.2-0.20.6-0.00.1-0.30.10.1-0.20.1
Incentive Sensitization - Responses1.51.51.8-1.31.2-1.2-1.21.3-1.2-1.2-1.3-1.1-1.1-1.2-1.1
Incentive Sensitization - Breakpoint2.02.02.4-1.51.4-1.4-1.41.5-1.4-1.3-1.5-1.3-1.3-1.4-1.3
Progressive ratio test 1 active lever presses1.71.72.51.3-1.21.21.2-0.71.51.51.11.61.51.11.5
Progressive ratio test 1 breakpoint2.12.13.31.5-1.31.31.3-0.71.61.71.21.81.71.21.7
Progressive ratio test 1 inactive lever presses0.10.10.7-0.10.2-0.2-0.20.90.10.2-0.30.30.2-0.30.2
Progressive ratio test 2 active lever presses0.20.20.50.3-0.20.20.20.40.50.60.10.70.60.20.6
Progressive ratio test 2 breakpoint0.10.10.5-0.10.0-0.0-0.10.70.10.2-0.30.30.2-0.10.2
Progressive ratio test 2 inactive lever presses0.40.51.0-0.70.7-0.7-0.71.0-0.6-0.5-0.8-0.4-0.5-0.7-0.5
Total sessions with >9 infusions0.10.10.20.2-0.20.20.20.30.30.40.10.50.40.10.4
Short access day 1 total inactive lever presses0.20.20.8-0.50.5-0.5-0.50.9-0.3-0.3-0.6-0.2-0.3-0.5-0.2
Short access day 10 total inactive lever presses0.20.20.40.4-0.20.20.20.30.60.60.20.70.70.20.7
Short access day 1 total infusions0.40.50.60.7-0.70.70.7-0.30.70.70.60.80.70.70.7
Short access day 10 total infusions0.40.40.5-0.70.6-0.6-0.60.5-0.7-0.7-0.5-0.7-0.7-0.6-0.7
Short access total infusions0.20.20.5-0.50.5-0.5-0.50.7-0.4-0.4-0.5-0.3-0.4-0.5-0.4
Short access day 1 locomotion0.20.30.5-0.50.3-0.3-0.30.1-0.6-0.7-0.5-0.7-0.7-0.3-0.7
Short access day 10 total locomotion1.92.12.4-1.51.5-1.5-1.51.3-1.4-1.4-1.5-1.3-1.4-1.5-1.4
Short access total locomotion1.81.92.1-1.41.4-1.4-1.41.3-1.4-1.3-1.4-1.2-1.3-1.5-1.3
Compulsive drug intake0.10.10.2-0.30.3-0.3-0.3-0.1-0.4-0.4-0.1-0.4-0.4-0.4-0.4
One hour access (0.3 mA shock)0.10.20.4-0.40.4-0.4-0.40.6-0.3-0.3-0.5-0.2-0.3-0.5-0.3
One hour access (shock baseline)0.00.10.10.2-0.30.30.20.00.20.30.10.30.30.30.3
Number of responses in last shaping day0.80.81.3-0.90.6-0.6-0.60.3-1.1-1.1-0.8-1.1-1.1-0.8-1.1
Context. condit. distance diff. score3.23.86.81.9-1.51.51.5-0.32.32.51.52.62.51.52.5
Locomotion velocity, session 10.10.10.2-0.20.2-0.2-0.2-0.1-0.3-0.4-0.2-0.4-0.4-0.1-0.4
Locomotion distance, session 11.92.53.4-1.61.5-1.5-1.50.7-1.7-1.8-1.6-1.8-1.8-1.3-1.8
Locomotion velocity, session 20.70.81.4-0.90.7-0.7-0.70.2-1.0-1.1-0.8-1.2-1.1-0.6-1.1
Locomotion distance, session 22.23.24.4-1.81.6-1.6-1.60.9-2.0-2.0-1.7-2.1-2.1-1.5-2.1
Locomotion velocity, session 31.51.72.21.3-1.31.31.3-1.51.31.31.31.21.21.41.2
Locomotion distance, session 30.80.91.21.0-0.90.90.9-0.71.01.10.91.11.10.81.1
Stereotopy head waving bouts, day 30.10.20.70.3-0.50.50.5-0.80.20.10.40.00.10.50.0
Stereotopy head waving duration, day 30.30.31.70.4-0.60.60.6-1.30.1-0.00.6-0.2-0.10.7-0.1
Locomotion velocity, session 71.81.94.61.1-0.60.60.60.91.71.90.52.12.00.72.0
Locomotion distance, session 70.60.82.20.30.2-0.2-0.21.50.91.1-0.31.31.2-0.11.2
Stereotopy head waving bouts, day 70.20.21.10.2-0.40.40.4-1.1-0.1-0.20.4-0.3-0.20.4-0.3
Stereotopy head waving duration, day 70.70.82.90.8-1.11.11.1-1.70.50.41.10.20.31.00.3
Locomotion velocity, session 81.11.31.51.2-1.21.21.2-0.91.21.21.11.21.21.11.2
Locomotion distance, session 80.10.10.20.10.1-0.1-0.10.40.30.4-0.10.50.4-0.00.4
Degree of sensitization distance1.01.05.3-0.71.1-1.1-1.12.3-0.20.0-1.20.30.1-1.00.2
Degree of sensitization stereotypy0.20.21.00.3-0.50.50.5-1.00.20.10.5-0.00.00.40.0
Condit. Reinf. active minus inactive responses0.30.40.7-0.60.4-0.4-0.4-0.0-0.7-0.8-0.4-0.8-0.8-0.5-0.8
Condit. Reinf. active-inactive response ratio1.11.12.01.1-1.21.21.2-1.40.90.81.20.80.81.10.8
Condit. Reinf. active responses2.22.73.4-1.71.5-1.5-1.51.0-1.8-1.8-1.6-1.8-1.9-1.6-1.9
Condit. Reinf. inactive responses8.39.910.8-3.23.2-3.2-3.22.8-3.2-3.1-3.3-3.0-3.1-3.1-3.1
Incentive salience index mean1.01.22.2-1.10.8-0.8-0.80.1-1.3-1.4-0.8-1.5-1.5-1.0-1.5
Condit. Reinf. lever presses2.33.04.5-1.81.5-1.5-1.50.6-2.0-2.1-1.5-2.1-2.1-1.6-2.1
Time in familiar zone, hab. session 10.00.00.10.1-0.10.10.10.10.20.20.10.30.30.10.3
Time in novel zone, hab. session 11.71.72.41.3-1.41.41.4-1.61.21.11.41.11.11.41.1
Total zone transitions, hab. session 10.40.61.0-0.80.7-0.7-0.70.2-0.9-0.9-0.7-1.0-0.9-0.6-1.0
Total locomotion distance, hab. session 11.42.02.4-1.41.3-1.3-1.30.8-1.5-1.5-1.4-1.6-1.6-1.3-1.6
Locomotion velocity, hab. session 13.24.75.5-2.22.1-2.1-2.11.5-2.3-2.3-2.2-2.3-2.3-2.1-2.3
Time in familiar zone, hab. session 24.34.54.92.2-2.12.12.1-1.62.22.22.22.22.22.02.2
Time in novel zone, hab. session 22.12.12.5-1.51.4-1.4-1.41.0-1.6-1.6-1.5-1.6-1.6-1.3-1.6
Total zone transitions, hab. session 20.30.41.1-0.50.2-0.2-0.2-0.8-0.8-0.9-0.2-1.0-0.9-0.1-1.0
Total locomotion distance, hab. session 20.30.40.8-0.60.4-0.4-0.4-0.3-0.7-0.8-0.4-0.9-0.8-0.3-0.8
Locomotion velocity, hab. session 20.40.51.1-0.60.4-0.4-0.4-0.4-0.8-0.9-0.4-1.1-1.0-0.3-1.0
Novel to familiar place preference ratio1.11.21.3-1.11.1-1.1-1.11.0-1.1-1.1-1.1-1.1-1.1-1.1-1.1
Novelty place preference1.11.21.3-1.11.0-1.0-1.00.9-1.1-1.1-1.0-1.1-1.1-1.1-1.1
Time in novel zone, NPP test0.80.91.1-0.90.8-0.8-0.80.7-1.0-1.0-0.8-1.0-1.0-0.9-1.0
Total zone transitions, NPP test1.42.02.2-1.41.4-1.4-1.41.0-1.5-1.5-1.5-1.5-1.5-1.3-1.5
Total locomotion distance, NPP test4.76.57.7-2.62.7-2.7-2.72.5-2.5-2.4-2.8-2.3-2.4-2.6-2.4
Locomotion velocity, NPP test4.05.87.0-2.52.5-2.5-2.52.4-2.3-2.2-2.6-2.2-2.2-2.5-2.2
Pavlov. Cond. lever latency1.31.72.11.3-1.21.21.2-0.71.41.41.21.51.51.21.5
Pavlov. Cond. magazine entry latency0.40.50.7-0.80.8-0.8-0.80.7-0.7-0.7-0.7-0.6-0.7-0.8-0.7
Pavlov. Cond. change in total contacts0.80.81.6-0.80.5-0.5-0.5-0.4-1.1-1.2-0.5-1.3-1.3-0.7-1.3
Pavlov. Cond. index score0.71.01.3-1.00.9-0.9-0.90.4-1.1-1.1-0.8-1.1-1.1-0.9-1.1
Pavlov. Cond. latency score1.01.31.7-1.21.1-1.1-1.10.6-1.3-1.3-1.0-1.3-1.3-1.1-1.3
Pavlov. Cond. lever contacts1.31.51.9-1.31.1-1.1-1.20.6-1.3-1.4-1.1-1.4-1.4-1.2-1.4
Pavlov. Cond. magazine entry number0.20.20.40.5-0.40.40.40.10.50.60.30.60.60.40.6
Pavlov. Cond. intertrial magazine entries1.92.32.7-1.61.4-1.4-1.41.0-1.6-1.7-1.5-1.6-1.7-1.5-1.7
Pavlov. Cond. lever-magazine prob. diff.0.60.71.0-0.90.7-0.7-0.70.2-1.0-1.0-0.7-1.0-1.0-0.8-1.0
Pavlov. Cond. response bias0.20.20.3-0.50.4-0.4-0.4-0.0-0.5-0.6-0.3-0.6-0.6-0.4-0.6
Bone: apparent density0.81.33.2-1.11.2-1.2-1.21.8-0.9-0.8-1.2-0.7-0.8-1.3-0.8
Bone surface1.12.02.6-1.41.4-1.4-1.41.6-1.4-1.3-1.4-1.3-1.3-1.5-1.3
Bone volume1.32.23.0-1.51.5-1.5-1.51.7-1.4-1.4-1.5-1.3-1.4-1.6-1.4
Bone: connectivity density0.61.03.4-0.91.1-1.1-1.11.9-0.6-0.5-1.1-0.4-0.5-1.2-0.4
Bone: cortical apparent density1.31.62.51.3-1.01.01.0-0.51.51.61.01.61.61.21.6
Bone: cortical area0.50.80.9-0.90.9-0.9-0.90.7-0.9-0.9-0.9-0.9-0.9-0.9-0.9
Bone: cortical porosity0.30.30.8-0.40.1-0.1-0.1-0.5-0.7-0.8-0.1-0.9-0.8-0.2-0.8
Bone: cortical porosity0.70.71.4-0.80.5-0.5-0.5-0.1-1.0-1.1-0.6-1.2-1.2-0.6-1.2
Bone: cortical thickness0.10.20.2-0.40.4-0.4-0.40.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4
Bone: cortical thickness0.40.50.80.7-0.60.60.6-0.00.80.90.60.90.90.70.9
Bone: cortical tissue density1.51.92.91.4-1.11.11.1-0.51.61.71.11.71.71.31.7
Bone: elastic displacement2.02.32.9-1.51.4-1.4-1.41.0-1.6-1.7-1.4-1.7-1.7-1.4-1.7
Bone: elastic work4.66.07.5-2.52.3-2.3-2.31.6-2.7-2.7-2.3-2.7-2.7-2.3-2.7
Bone: endosteal estimation0.20.40.5-0.70.6-0.6-0.60.5-0.7-0.7-0.6-0.7-0.7-0.7-0.7
Bone: endosteal perimeter0.81.61.9-1.31.2-1.2-1.20.8-1.4-1.4-1.2-1.4-1.4-1.3-1.4
Bone: final force0.10.10.2-0.40.3-0.3-0.30.3-0.4-0.4-0.3-0.4-0.4-0.5-0.4
Bone: final moment0.50.81.0-0.90.8-0.8-0.80.7-1.0-1.0-0.8-1.0-1.0-1.0-1.0
Bone: marrow area0.30.60.7-0.80.8-0.8-0.80.7-0.8-0.8-0.8-0.8-0.8-0.8-0.8
Bone: maximum diameter0.00.00.10.1-0.10.10.1-0.30.0-0.00.2-0.1-0.00.1-0.0
Bone: maximum force0.20.40.6-0.60.4-0.4-0.40.3-0.7-0.7-0.4-0.8-0.8-0.6-0.8
Bone: maximum moment0.81.52.0-1.21.1-1.1-1.10.7-1.3-1.4-1.1-1.4-1.4-1.2-1.4
Bone: minimum diameter1.01.92.6-1.41.3-1.3-1.30.7-1.5-1.6-1.3-1.6-1.6-1.3-1.6
Bone: periosteal estimation0.40.90.9-1.00.9-0.9-1.00.8-1.0-1.0-0.9-1.0-1.0-1.0-1.0
Bone: periosteal perimeter0.61.11.2-1.11.0-1.0-1.00.8-1.1-1.1-1.0-1.1-1.1-1.0-1.1
Bone: post-yield work0.70.91.60.9-0.70.70.7-0.01.11.20.71.31.20.71.2
Bone: stiffness0.20.30.40.5-0.60.60.6-0.60.50.50.60.40.50.50.5
Bone: tissue strength0.70.71.0-0.90.8-0.8-0.80.7-0.9-0.9-0.8-0.8-0.9-1.0-0.9
Bone: trabecular number1.21.84.1-1.31.5-1.5-1.52.0-1.1-1.0-1.5-0.9-1.0-1.5-0.9
Bone: trabecular spacing0.91.23.11.1-1.21.21.2-1.80.80.71.30.60.71.20.6
Bone: trabecular thickness1.31.52.2-1.31.3-1.3-1.31.5-1.2-1.1-1.3-1.1-1.1-1.2-1.1
Bone: trabecular tissue density0.20.31.00.5-0.70.70.7-1.00.30.20.70.20.20.70.2
Breakpoint value in progressive ratio session0.20.20.30.5-0.40.40.4-0.40.40.40.50.40.40.50.4
Distance traveled before self-admin0.20.20.60.1-0.40.40.4-0.8-0.1-0.30.4-0.4-0.30.4-0.3
Distance traveled after self-admin0.80.91.50.9-1.11.11.1-1.20.70.61.20.50.61.10.6
Delta time in closed arm before/after self-admin0.50.40.6-0.70.7-0.7-0.70.7-0.6-0.6-0.8-0.5-0.5-0.7-0.5
Delta time in open arm before/after self-admin0.20.20.40.5-0.30.30.30.10.60.60.50.60.60.20.6
Diff in mean of infusions in LGA sessions0.10.10.60.2-0.50.50.4-0.80.0-0.10.3-0.1-0.10.5-0.1
Extinction: sum of active levers before priming1.21.22.6-1.11.3-1.3-1.31.6-0.8-0.7-1.1-0.6-0.7-1.2-0.7
Active lever presses in extinction session 60.10.10.20.10.1-0.1-0.10.40.30.40.10.40.4-0.10.4
Delta distance traveled before/after self-admin2.32.53.01.6-1.61.61.6-1.51.61.51.71.51.51.61.5
Delta ambulatory time before/after self-admin1.51.61.91.3-1.31.31.3-1.41.21.21.41.11.21.31.2
Time in closed arm before self-admin0.91.01.51.0-1.21.21.2-1.00.90.80.90.80.81.20.8
Time in closed arm after self-admin0.00.00.10.1-0.30.30.3-0.3-0.0-0.1-0.1-0.1-0.10.2-0.1
Time in open arm before self-admin0.20.20.3-0.50.4-0.4-0.40.1-0.5-0.5-0.5-0.5-0.5-0.4-0.5
Time in open arm after self-admin0.00.10.10.10.1-0.1-0.10.10.30.30.30.30.3-0.00.3
Sum of active levers in priming session hrs 5-60.80.81.40.9-0.70.70.7-0.11.11.10.81.21.20.71.2
Time to tail flick, vehicle, before self-admin1.31.41.5-1.21.2-1.2-1.21.2-1.1-1.1-1.2-1.0-1.1-1.2-1.1
Time to tail flick, vehicle, after self-admin5.25.66.72.4-2.62.62.6-2.52.22.12.42.02.12.62.1
Time to tail flick, test, before self-admin2.02.02.4-1.51.5-1.5-1.51.4-1.4-1.3-1.3-1.3-1.3-1.6-1.3
Time to tail flick, test, after self-admin0.50.52.30.00.4-0.4-0.41.50.50.7-0.50.90.8-0.50.8
Delta time to tail flick, vehicle, before/after SA4.03.94.22.1-2.02.02.0-1.72.02.01.92.02.02.02.0
Delta time to tail flick, test, before/after SA3.02.74.91.6-1.21.21.2-0.32.02.11.12.22.11.32.1
Ambulatory time before self-admin0.20.20.4-0.30.2-0.2-0.2-0.2-0.5-0.6-0.1-0.7-0.6-0.2-0.6
Ambulatory time after self-admin0.91.02.60.9-1.21.21.2-1.60.70.51.30.40.51.10.5
Total heroin consumption0.10.20.60.3-0.50.50.5-0.70.10.00.3-0.0-0.00.6-0.0
Area under the delay curve0.10.20.3-0.40.3-0.3-0.30.1-0.5-0.5-0.2-0.5-0.5-0.3-0.5
Delay disc. indifference point, 0s delay2.22.42.7-1.61.5-1.5-1.51.2-1.6-1.7-1.4-1.6-1.7-1.6-1.6
Delay disc. indifference point, 16s delay0.00.00.10.0-0.00.00.00.30.10.1-0.10.20.10.10.1
Delay disc. indifference point, 2s delay0.80.91.7-0.90.6-0.6-0.6-0.3-1.1-1.3-0.6-1.3-1.3-0.7-1.3
Delay disc. indifference point, 24s delay0.20.20.50.5-0.50.50.5-0.30.40.40.50.30.40.70.4
Delay disc. indifference point, 4s delay0.40.41.50.5-0.70.70.7-1.20.40.30.90.20.20.60.2
Delay disc. indifference point, 8s delay0.10.10.1-0.40.3-0.3-0.30.4-0.3-0.3-0.3-0.3-0.3-0.4-0.3
Delay discount exponential model param0.00.00.10.2-0.10.10.10.20.30.3-0.00.30.30.10.3
Delay discount hyperbolic model param0.10.10.20.2-0.00.00.00.40.40.4-0.10.50.40.10.4
Fecal boli incidents, locomotor time 10.00.00.1-0.10.0-0.0-0.0-0.1-0.2-0.2-0.1-0.2-0.2-0.1-0.2
Change in fecal boli incidents, locomotor task1.81.72.11.4-1.41.41.4-1.11.31.31.51.31.31.31.3
Time >=10cm from walls, locomotor time 11.51.52.2-1.21.3-1.3-1.31.3-1.1-1.1-1.2-1.0-1.1-1.5-1.1
Bouts of movement, locomotor time 12.83.24.71.8-1.91.91.9-2.21.61.51.91.41.52.01.5
Total resting periods, locomotor time 15.15.66.52.4-2.52.52.5-2.52.32.22.42.12.22.52.2
Rest time, locomotor task time 15.15.55.92.4-2.42.42.4-2.32.32.32.42.22.32.42.3
Distance moved, locomotor task time 12.42.63.1-1.71.7-1.7-1.71.7-1.6-1.5-1.8-1.5-1.5-1.5-1.5
Vertical activity count, locomotor time 12.93.14.6-1.81.5-1.5-1.50.9-2.0-2.1-1.5-2.1-2.1-1.4-2.1
Time >=10cm from walls, locomotor time 20.10.10.30.3-0.30.30.3-0.50.30.20.40.20.20.30.2
Bouts of movement, locomotor time 24.65.05.82.3-2.32.32.3-2.42.22.12.32.02.12.42.1
Total resting periods, locomotor time 26.77.18.02.7-2.82.82.8-2.72.62.62.72.52.62.82.5
Rest time, locomotor task time 25.66.57.02.6-2.62.62.6-2.02.62.62.52.62.62.52.6
Distance moved, locomotor task time 25.26.16.5-2.52.6-2.6-2.62.3-2.5-2.5-2.5-2.4-2.4-2.4-2.4
Vertical activity count, locomotor time 23.94.36.1-2.11.8-1.8-1.81.2-2.3-2.4-1.9-2.5-2.4-1.7-2.4
Weight adjusted by age0.20.20.6-0.30.1-0.1-0.1-0.7-0.5-0.70.0-0.8-0.7-0.1-0.7
Seeking ratio, delayed vs. immediate footshock3.13.53.8-1.91.8-1.8-1.81.7-1.9-1.9-1.9-1.9-1.9-2.0-1.9
Locomotion in novel chamber0.10.10.3-0.30.4-0.4-0.40.2-0.3-0.3-0.0-0.3-0.3-0.5-0.3
Locomotion in novel chamber post-restriction0.40.50.80.7-0.70.70.7-0.90.60.60.80.50.60.70.6
Progressive ratio0.00.10.1-0.10.1-0.1-0.1-0.4-0.2-0.30.1-0.4-0.30.0-0.3
Food seeking constrained by brief footshock7.18.69.53.0-2.92.92.9-2.23.13.12.83.13.13.03.1
Seeking ratio, punishment vs. effort1.92.33.01.6-1.51.51.5-0.91.61.71.41.71.71.51.7
Run reversals in cocaine runway, females1.41.43.2-1.21.3-1.3-1.31.8-1.0-0.9-1.3-0.8-0.8-1.2-0.8
Run reversals in cocaine runway, males0.90.92.90.9-1.01.01.0-1.70.60.51.30.30.41.00.4
Latency to leave start box in cocaine runway1.41.53.11.2-1.31.31.3-1.81.00.91.60.80.91.20.9
Latency to leave start box in cocaine runway, F1.71.94.61.3-1.51.51.5-2.21.11.01.70.80.91.50.9
Latency to leave start box in cocaine runway, M0.30.30.6-0.50.6-0.6-0.60.8-0.4-0.4-0.3-0.4-0.4-0.7-0.4
Cd content in liver0.50.50.6-0.70.7-0.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7
Co content in liver3.94.65.32.2-2.32.32.3-2.32.12.02.31.91.92.31.9
Cu content in liver1.11.31.61.2-1.21.21.2-1.21.11.01.21.01.01.21.0
Fe content in liver0.60.71.7-0.81.0-1.0-1.01.3-0.6-0.5-1.0-0.4-0.4-0.9-0.4
K content in liver0.00.00.20.00.0-0.0-0.00.50.10.2-0.00.30.2-0.10.2
Mg content in liver0.10.10.5-0.20.3-0.3-0.30.7-0.1-0.0-0.30.10.0-0.40.0
Mn content in liver1.41.62.9-1.31.4-1.4-1.41.7-1.1-1.0-1.4-0.8-1.0-1.5-1.0
Na content in liver2.52.74.7-1.61.2-1.2-1.20.1-1.9-2.1-1.2-2.2-2.1-1.3-2.1
Rb content in liver0.20.20.40.4-0.30.30.30.20.50.60.30.60.60.20.6
Se content in liver4.55.46.7-2.42.2-2.2-2.21.6-2.5-2.6-2.2-2.6-2.6-2.2-2.6
Sr content in liver0.20.20.3-0.50.5-0.5-0.50.5-0.4-0.4-0.5-0.4-0.4-0.5-0.4
Zn content in liver0.91.02.0-0.90.7-0.7-0.7-0.2-1.2-1.3-0.7-1.4-1.3-0.6-1.3