Hub : Genes

Cyp7b1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000009730 0.43 0.15 0.0e+00 0.27 0.27 0.29 0.28 8.6e-15 7.3e-15 5.8e-16 2.3e-15
2 Brain gene expression ENSRNOG00000009730 0.32 0.13 0.0e+00 0.27 0.27 0.28 0.27 2.8e-25 1.1e-24 7.1e-26 2.4e-25
3 Brain intron excision ratio chr2:100638373:100669465 0.04 0.03 1.1e-03 0.02 0.03 0.04 0.03 2.6e-03 7.5e-04 2.6e-04 5.4e-04
4 Brain intron excision ratio chr2:100660904:100669465 0.04 0.03 1.7e-03 0.02 0.03 0.04 0.03 3.2e-03 9.8e-04 1.1e-04 6.8e-04
5 Brain mRNA stability ENSRNOG00000009730 0.05 0.03 4.4e-04 0.03 0.01 0.01 0.02 7.4e-04 1.4e-02 2.5e-02 2.7e-03
6 IL gene expression ENSRNOG00000009730 0.18 0.12 2.4e-03 0.08 0.04 0.06 0.07 6.5e-03 4.0e-02 1.2e-02 8.0e-03
7 Liver gene expression ENSRNOG00000009730 0.98 0 0.0e+00 0.31 0.38 0.4 0.4 6.9e-35 1.7e-44 1.5e-47 1.3e-47
8 Liver isoform ratio ENSRNOT00000013116 0.06 0.05 6.6e-04 0.01 0.01 0.03 0.01 1.0e-02 4.5e-02 2.0e-04 6.4e-02
9 Liver mRNA stability ENSRNOG00000009730 0.14 0.09 7.8e-10 0.05 0.06 0.06 0.06 2.5e-06 1.9e-07 1.3e-07 1.9e-07
10 NAcc gene expression ENSRNOG00000009730 0.16 0.1 1.8e-09 0.1 0.09 0.1 0.09 9.8e-08 2.1e-07 6.3e-08 2.9e-07
11 PL gene expression ENSRNOG00000009730 0.1 0.06 1.1e-07 0.06 0.07 0.06 0.06 2.0e-05 3.9e-06 1.3e-05 1.8e-05
12 PL isoform ratio ENSRNOT00000013116 0.05 0.04 9.3e-03 0 0 0.04 0.02 2.2e-01 2.2e-01 6.8e-04 8.3e-03
13 PL intron excision ratio chr2:100660904:100669465 0.18 0.12 1.6e-03 0.02 0.04 0.01 0.02 5.8e-03 1.0e-03 9.1e-02 6.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail1.75.59.22.52.52.7-2.52.12.4-2.2-0.5-2.91.92.51.7-3.0
BMI without tail2.34.86.82.32.22.4-2.32.42.5-2.3-0.9-2.21.12.32.6-2.0
Body weight1.98.112.83.23.13.4-3.32.73.2-2.2-0.2-3.62.43.11.7-3.2
Epididymis fat weight4.09.414.53.43.43.7-3.83.22.6-2.01.3-3.83.23.40.7-3.2
Glucose0.61.02.31.11.01.1-1.21.01.1-0.60.4-1.50.91.10.3-0.7
Heart weight0.10.21.3-0.4-0.1-0.10.3-0.5-0.6-0.40.2-0.2-0.1-0.10.2-1.1
Left kidney weight0.10.21.4-0.5-0.1-0.30.4-0.4-0.10.01.20.2-0.4-0.20.6-0.3
Right kidney weight0.41.12.90.91.21.2-1.10.91.1-0.31.7-1.00.81.10.5-1.1
Tail length0.61.93.61.61.61.7-1.81.91.9-0.40.5-0.91.01.71.0-0.2
Length with tail0.72.54.11.91.91.9-2.01.61.90.00.9-1.61.81.9-0.1-1.1
Length without tail0.40.92.60.80.80.8-0.90.20.60.71.0-1.21.50.7-1.6-0.9
Liver weight, left3.35.48.62.82.62.9-2.92.72.2-1.9-0.4-2.21.82.71.7-2.2
Liver weight, right1.42.33.91.72.01.9-1.71.91.7-0.70.1-0.41.11.91.7-1.2
Parametrial fat weight2.95.810.22.92.52.8-3.02.63.1-1.51.0-3.22.02.61.2-1.5
Retroperitoneal fat weight2.58.211.23.23.33.3-3.13.02.8-2.30.1-2.92.43.32.5-3.3
Intraocular pressure2.43.38.41.61.51.6-1.31.21.0-2.3-2.6-2.31.41.51.3-2.9
Extensor digitorum longus weight5.622.531.65.55.35.6-5.55.35.3-3.7-0.7-4.83.65.54.0-4.4
Soleus weight0.41.11.91.31.31.3-1.41.31.2-0.40.3-1.01.01.30.3-0.6
Tibialis anterior weight5.418.727.85.15.15.3-5.15.15.1-2.8-0.4-3.63.35.23.8-3.6
Tibia length0.10.30.50.60.50.6-0.70.50.40.20.5-0.70.70.5-0.6-0.1
Number of licking bursts2.22.64.62.01.82.0-2.11.71.5-0.9-0.1-2.11.71.80.1-1.3
Food consumed during 24 hour testing period3.84.66.42.52.32.5-2.52.32.4-1.8-0.4-2.51.52.41.8-2.0
Times rat made contact with spout3.33.86.92.42.22.4-2.62.22.2-0.50.8-2.22.12.2-0.1-1.1
Mean time between licks in bursts0.60.83.60.30.30.3-0.20.30.7-1.7-0.3-1.2-0.40.31.9-1.3
Mean num. licks in bursts0.40.41.0-0.7-0.5-0.60.6-0.5-0.20.80.71.0-0.6-0.6-0.30.9
Std. dev. time between licks in bursts0.40.51.1-0.7-1.0-0.80.7-1.0-0.6-0.5-0.1-1.0-0.6-0.9-0.40.0
Water consumed over 24 hours0.30.40.80.70.50.7-0.70.50.0-0.5-0.7-0.90.50.60.0-0.7
Indifference point 0 sec0.20.41.40.30.50.3-0.40.50.71.11.20.60.40.50.10.8
Indifference point AUC0.10.10.3-0.1-0.1-0.10.10.10.3-0.50.5-0.3-0.3-0.10.5-0.1
Indifference point function ln k0.91.32.31.11.11.2-1.01.01.0-1.4-0.5-1.20.71.21.5-1.5
Indifference point function log k0.91.32.31.11.11.2-1.01.01.0-1.4-0.5-1.20.71.21.5-1.5
Delay discounting total patch changes 0 sec0.40.61.40.70.80.8-0.80.91.20.61.10.10.60.90.50.5
Delay discounting total patch changes 12 sec0.10.21.8-0.10.10.1-0.10.00.20.41.3-0.10.30.0-0.50.2
Delay discounting total patch changes 18 sec0.10.20.60.10.20.1-0.20.40.70.40.80.2-0.10.20.30.7
Delay discounting total patch changes 24 sec0.10.20.4-0.5-0.4-0.40.5-0.4-0.20.00.30.5-0.7-0.40.50.2
Delay discounting total patch changes 6 sec0.30.41.20.50.70.6-0.40.71.10.10.90.10.30.70.9-0.0
Delay discounting time to switch 0 sec0.10.20.40.50.60.6-0.50.50.10.4-0.00.10.60.5-0.3-0.3
Delay discounting water rate 0 sec0.20.21.2-0.3-0.3-0.30.3-0.20.3-0.3-0.30.6-0.9-0.21.10.4
Delay discounting water rate 12 sec0.50.81.8-0.9-1.4-1.21.0-1.1-0.6-0.4-0.20.1-1.2-1.30.10.8
Delay discounting water rate 18 sec0.40.51.3-0.7-1.0-0.90.8-0.7-0.5-0.4-0.20.3-1.1-0.90.40.8
Delay discounting water rate 24 sec0.30.41.5-0.4-0.7-0.40.4-0.6-0.5-1.2-0.6-0.7-0.7-0.60.4-0.5
Delay discounting water rate 6 sec0.30.41.60.60.20.4-0.50.60.8-0.9-0.3-0.4-0.40.41.30.1
Locomotor activity1.01.63.81.31.31.3-1.21.11.1-1.2-0.7-1.51.41.30.7-2.0
Locomotor testing distance1.42.33.81.71.61.7-1.61.31.4-1.1-0.8-1.91.71.60.4-1.9
Locomotor testing rearing0.10.20.60.20.10.1-0.2-0.10.0-0.0-0.4-0.70.70.0-0.8-0.5
Light reinforcement 11.01.94.01.51.61.7-1.51.11.3-0.90.1-1.41.31.50.6-2.0
Light reinforcement 22.53.36.02.12.42.2-2.22.12.50.51.5-0.52.02.30.3-0.8
Reaction time number correct0.60.82.0-0.9-1.2-1.00.8-1.3-1.10.3-0.40.0-0.4-1.1-1.40.4
Reaction time mean minus median6.28.112.43.02.62.9-2.62.62.5-3.5-2.3-3.31.52.83.4-3.4
Reaction time mean minus median AUC6.48.114.72.82.42.7-2.42.42.4-3.8-2.3-3.61.32.63.6-3.7
Reaction time num false alarms1.21.75.8-1.4-1.5-1.41.3-1.7-1.60.6-0.5-0.3-0.2-1.5-2.40.2
Reaction time num false alarms AUC0.91.25.6-1.0-1.1-1.00.9-1.4-1.40.4-0.6-0.80.2-1.2-2.4-0.1
Reaction time trials correct on left0.60.82.0-0.9-1.2-1.00.8-1.3-1.10.3-0.40.0-0.4-1.1-1.40.4
Reaction time trials on left0.50.71.9-0.8-1.2-0.90.7-1.2-1.10.2-0.5-0.1-0.4-1.1-1.40.3
Reaction time mean2.73.87.42.01.51.7-1.61.51.1-2.7-2.4-2.71.31.51.6-2.6
Reaction time mean AUC2.73.68.01.81.31.5-1.31.30.8-2.8-2.6-2.61.21.41.6-2.8
Median of all reaction times1.52.05.21.40.91.1-1.01.00.4-2.1-2.3-1.91.00.90.8-2.0
Reaction time omissions3.44.710.22.11.82.0-1.91.71.5-2.8-2.0-3.21.51.81.8-3.1
Reaction time false alarm rate0.30.42.5-0.4-0.4-0.40.4-0.6-0.70.5-0.0-0.50.4-0.5-1.6-0.0
Reaction time premature initiation rate0.40.64.0-0.1-0.4-0.40.5-0.2-0.4-1.0-2.00.1-0.6-0.31.1-0.2
Reaction time premature initiations0.50.74.7-0.3-0.8-0.60.6-0.7-0.8-1.1-2.2-0.2-0.7-0.60.5-0.3
Std. dev. reaction times4.86.510.92.72.32.5-2.32.42.0-3.1-2.5-3.31.62.42.4-3.1
Reaction time trials completed0.50.71.9-0.8-1.2-0.90.7-1.2-1.10.2-0.5-0.1-0.4-1.1-1.40.3
Reaction time trials AUC0.40.61.9-0.7-1.0-0.80.6-1.1-0.90.3-0.4-0.1-0.3-0.9-1.40.4
Social response proportion0.30.31.10.30.30.4-0.40.2-0.2-1.00.1-1.00.30.30.1-1.0
Social responses1.01.32.81.21.11.4-1.30.90.8-0.90.5-1.71.11.10.1-1.5
Social time0.20.30.8-0.6-0.6-0.50.5-0.6-0.9-0.20.2-0.0-0.5-0.6-0.50.1
Conditioned locomotion2.02.46.4-1.8-1.4-1.71.8-1.4-1.41.70.82.5-1.1-1.4-0.81.7
Cocaine response after cond. corrected0.10.20.6-0.2-0.5-0.30.2-0.4-0.4-0.2-0.8-0.3-0.2-0.5-0.50.1
Cocaine response after cond. not corrected0.20.20.7-0.1-0.5-0.30.2-0.5-0.3-0.4-0.9-0.5-0.2-0.5-0.5-0.1
Cocaine response before conditioning0.10.20.3-0.3-0.5-0.30.4-0.5-0.5-0.4-0.5-0.2-0.3-0.4-0.1-0.4
Saline control response0.40.61.50.80.70.9-0.90.61.0-0.50.2-1.20.70.80.3-0.7
Condit. Reinf. active minus inactive responses0.30.40.90.70.60.7-0.80.60.3-0.2-0.1-0.90.90.6-0.5-0.7
Condit. Reinf. active-inactive response ratio0.40.41.10.60.50.5-0.50.40.2-0.8-0.6-1.00.70.5-0.0-1.0
Condit. Reinf. active responses0.20.30.80.60.40.6-0.70.40.1-0.2-0.3-0.90.80.4-0.9-0.5
Condit. Reinf. inactive responses0.20.21.40.40.20.4-0.60.20.10.40.2-0.40.60.2-1.20.2
Condit. Reinf. lever presses0.20.30.7-0.6-0.7-0.60.5-0.6-0.50.20.2-0.1-0.4-0.7-0.90.5
Condit. Reinf. lever reinforcers received0.20.20.80.50.30.5-0.60.30.1-0.2-0.2-0.90.70.3-0.8-0.5
Pavlov. Cond. lever latency0.71.03.90.30.10.3-0.00.1-0.1-1.6-1.9-0.4-0.40.32.0-1.3
Pavlov. Cond. magazine entry latency0.40.42.40.40.00.3-0.4-0.00.1-1.1-0.4-1.60.30.1-0.1-1.0
Pavlov. Cond. change in total contacts0.40.53.0-0.4-0.3-0.30.1-0.2-0.31.11.10.20.4-0.4-1.70.8
Pavlov. Cond. index score0.20.21.10.0-0.10.0-0.2-0.00.20.21.0-0.60.4-0.1-1.10.1
Pavlov. Cond. latency score0.20.21.10.10.00.1-0.30.10.30.20.9-0.60.5-0.0-1.10.2
Pavlov. Cond. lever contacts0.91.24.6-0.5-0.4-0.50.2-0.3-0.11.82.00.70.3-0.5-2.11.5
Pavlov. Cond. magazine entry number0.10.21.0-0.20.0-0.20.30.0-0.20.3-0.41.0-0.40.00.80.3
Pavlov. Cond. intertrial magazine entries0.20.31.4-0.3-0.4-0.40.4-0.4-0.6-0.5-1.2-0.2-0.3-0.40.2-0.4
Pavlov. Cond. lever-magazine prob. diff.0.20.31.00.30.20.3-0.50.20.50.11.0-0.90.60.1-0.9-0.1
Pavlov. Cond. response bias0.40.63.1-0.3-0.3-0.30.1-0.3-0.11.11.40.00.3-0.4-1.80.9
Conditioned reinforcement - actives0.50.51.7-0.9-0.6-1.01.2-0.5-0.60.4-0.11.3-0.3-0.60.20.5
Conditioned reinforcement - inactives0.50.62.1-0.7-0.3-0.70.9-0.0-0.10.10.31.4-1.0-0.31.50.8
Conditioned locomotion0.60.71.61.01.10.8-0.81.20.9-0.10.30.20.81.01.1-0.3
Intermittent access intake day 1-15 change1.11.12.11.21.21.1-1.11.21.3-0.6-1.0-0.40.41.21.4-0.7
Intermittent access intake escalation0.60.62.50.80.80.6-0.50.91.1-0.3-0.80.40.00.91.6-0.3
Intermittent access intake escalation 20.60.62.20.70.70.6-0.60.91.5-0.20.60.1-0.10.71.40.1
Intermitt. access day 1 inactive lever presses1.01.14.1-1.2-0.4-0.91.4-0.6-0.50.00.12.0-1.3-0.51.8-0.2
Intermitt. access day 15 inactive lever presses0.91.03.0-1.2-0.7-1.11.5-0.7-0.80.10.11.7-1.3-0.80.90.4
Intermitt. access escalation Index0.40.30.7-0.8-0.6-0.70.8-0.8-0.50.20.10.6-0.7-0.7-0.10.2
Intermittent access day 1 total infusions0.70.74.7-0.8-0.4-0.81.1-0.1-0.50.6-0.22.2-0.6-0.40.80.8
Intermittent access day 15 total infusions0.91.06.4-0.5-0.0-0.60.90.3-0.00.5-1.12.5-0.8-0.01.70.8
Intermittent access terminal intake (last 3 days)1.11.37.50.20.80.30.11.20.90.0-0.22.2-0.40.82.70.3
Intermittent access total infusions1.11.28.0-0.8-0.1-0.61.10.2-0.40.4-0.62.8-0.8-0.12.00.6
Intermittent access day 1 locomotion0.60.61.70.90.90.7-0.61.00.6-0.3-1.30.10.71.00.8-0.6
Intermittent access day 15 total locomotion1.01.12.41.21.31.0-1.01.61.4-0.2-0.30.30.71.31.5-0.2
Intermittent access total locomotion0.91.02.21.01.20.9-0.71.40.8-0.3-1.10.60.81.21.5-0.6
Intermittent access standard deviation1.11.24.40.91.20.8-0.71.61.4-0.3-0.50.80.21.22.10.1
Cocaine induced anxiety0.10.10.7-0.1-0.4-0.30.1-0.3-0.20.4-0.1-0.20.2-0.3-0.80.3
Post-drug Anxiety0.50.50.9-0.8-0.8-0.90.8-0.7-0.60.50.60.6-0.7-0.8-0.61.0
Baseline Anxiety0.60.62.2-0.8-0.5-0.70.8-0.5-0.00.21.50.9-1.2-0.60.70.8
Lifetime Intake1.11.27.7-0.8-0.2-0.71.20.1-0.50.5-0.52.8-0.9-0.21.80.8
Incentive Sensitization - Responses1.01.03.1-1.1-0.8-1.11.3-0.7-0.50.60.31.8-1.1-0.90.51.1
Incentive Sensitization - Breakpoint0.90.93.1-1.0-0.8-1.11.3-0.7-0.40.60.31.7-1.1-0.80.51.1
Progressive ratio test 1 active lever presses0.60.62.20.80.90.7-0.51.20.7-0.3-0.70.50.40.91.5-0.2
Progressive ratio test 1 breakpoint0.50.52.20.60.90.6-0.41.10.7-0.2-0.60.60.20.81.5-0.1
Progressive ratio test 1 inactive lever presses1.11.12.5-1.4-0.9-1.31.6-1.1-1.10.4-0.21.6-1.2-1.00.60.2
Progressive ratio test 2 active lever presses0.80.84.1-0.9-0.5-0.91.2-0.3-0.60.5-0.42.0-0.8-0.51.00.7
Progressive ratio test 2 breakpoint0.40.42.6-0.4-0.0-0.50.70.1-0.00.3-0.11.6-0.4-0.11.10.5
Progressive ratio test 2 inactive lever presses0.80.94.3-0.9-0.2-0.71.2-0.2-0.30.20.12.1-1.0-0.31.70.3
Total sessions with >9 infusions0.50.51.10.90.80.7-0.81.00.1-0.2-0.8-0.40.90.80.3-0.4
Short access day 1 total inactive lever presses0.30.31.5-0.5-0.4-0.50.5-0.6-1.2-0.1-0.3-0.30.1-0.5-0.8-0.4
Short access day 10 total inactive lever presses0.60.71.5-1.0-0.9-1.01.0-1.1-0.40.31.20.3-0.6-1.0-0.60.3
Short access day 1 total infusions1.51.62.21.51.51.5-1.41.41.2-0.8-0.2-1.31.31.50.8-1.2
Short access day 10 total infusions0.80.95.4-0.7-0.1-0.71.10.1-0.30.40.02.3-0.7-0.21.70.6
Short access total infusions0.30.42.0-0.30.0-0.30.50.3-0.00.30.11.4-0.4-0.01.20.6
Short access day 1 locomotion0.40.40.80.80.80.7-0.80.90.7-0.4-0.3-0.60.70.80.5-0.4
Short access day 10 total locomotion0.30.31.60.60.60.4-0.40.70.4-0.1-1.30.20.50.60.5-0.4
Short access total locomotion0.50.50.80.90.80.7-0.70.90.6-0.2-0.9-0.20.80.90.5-0.5
Compulsive drug intake1.81.84.0-1.8-1.3-1.51.9-1.5-1.30.60.32.0-1.4-1.4-0.20.7
One hour access (0.3 mA shock)2.22.611.9-1.6-1.0-1.62.0-0.7-0.71.00.33.4-1.7-1.01.71.7
One hour access (shock baseline)1.01.25.1-1.1-0.8-1.21.4-0.4-0.50.90.22.3-0.9-0.80.71.4
Number of responses in last shaping day2.62.64.12.01.81.9-2.02.01.6-0.9-0.5-1.81.81.90.7-1.1
Context. condit. distance diff. score0.40.51.00.80.80.8-0.90.80.60.40.5-0.31.00.8-0.7-0.0
Locomotion velocity, session 10.50.50.90.70.60.7-0.70.60.6-0.9-0.4-0.90.20.70.9-0.8
Locomotion distance, session 10.10.10.5-0.00.20.10.10.1-0.00.1-0.10.4-0.30.10.7-0.0
Locomotion velocity, session 22.12.54.81.71.91.8-1.61.81.6-1.4-0.4-0.80.81.92.2-1.6
Locomotion distance, session 20.10.20.60.20.20.2-0.20.2-0.0-0.7-0.8-0.50.00.20.6-0.5
Locomotion velocity, session 30.81.01.91.21.21.2-1.21.21.4-0.50.4-0.90.61.20.9-0.5
Locomotion distance, session 30.80.81.71.10.91.0-1.10.91.1-0.90.1-1.30.60.90.7-0.8
Stereotopy head waving bouts, day 30.10.10.5-0.4-0.4-0.40.3-0.4-0.30.40.10.0-0.0-0.4-0.70.4
Stereotopy head waving duration, day 30.30.30.6-0.7-0.7-0.70.7-0.7-0.80.4-0.20.5-0.4-0.7-0.50.4
Locomotion velocity, session 71.41.53.5-1.3-1.5-1.41.2-1.5-1.60.9-0.10.5-0.6-1.5-1.91.0
Locomotion distance, session 71.31.73.8-1.2-1.6-1.41.3-1.6-2.00.3-0.90.1-0.6-1.6-1.80.7
Stereotopy head waving bouts, day 70.40.51.10.50.90.7-0.50.80.80.81.10.80.50.80.30.2
Stereotopy head waving duration, day 70.30.40.70.50.90.7-0.50.80.80.30.80.30.40.80.7-0.1
Locomotion velocity, session 81.01.22.31.21.51.3-1.21.51.3-0.20.6-0.00.71.41.2-0.6
Locomotion distance, session 81.01.52.81.41.71.6-1.51.71.5-0.10.5-0.51.21.60.7-0.6
Degree of sensitization distance3.23.36.7-2.1-2.2-2.22.1-2.2-2.60.5-1.21.3-1.4-2.2-1.41.0
Degree of sensitization stereotypy2.02.24.11.52.01.8-1.72.01.90.41.30.11.21.91.0-0.4
Condit. Reinf. active minus inactive responses0.00.10.20.10.30.1-0.00.30.10.20.10.5-0.00.20.40.1
Condit. Reinf. active-inactive response ratio0.00.00.1-0.00.00.00.1-0.0-0.3-0.3-0.4-0.1-0.10.00.4-0.4
Condit. Reinf. active responses0.10.20.80.40.50.4-0.30.50.4-0.3-0.2-0.10.10.50.9-0.3
Condit. Reinf. inactive responses0.40.51.10.70.70.7-0.70.80.9-0.7-0.2-0.60.20.71.0-0.5
Incentive salience index mean0.10.20.40.40.50.5-0.40.60.5-0.00.10.00.20.50.6-0.1
Condit. Reinf. lever presses0.30.51.50.60.50.6-0.50.60.6-0.9-0.5-0.70.10.61.2-0.8
Time in familiar zone, hab. session 10.10.00.2-0.3-0.2-0.20.3-0.1-0.40.1-0.10.4-0.2-0.20.00.1
Time in novel zone, hab. session 10.20.20.30.50.50.5-0.50.50.6-0.20.0-0.40.40.50.3-0.3
Total zone transitions, hab. session 10.20.20.50.40.40.4-0.30.30.0-0.7-0.7-0.60.10.40.5-0.7
Total locomotion distance, hab. session 10.10.10.20.40.40.4-0.40.40.1-0.2-0.5-0.30.30.40.1-0.5
Locomotion velocity, hab. session 10.20.30.50.60.60.6-0.50.50.2-0.6-0.6-0.60.40.60.4-0.7
Time in familiar zone, hab. session 20.30.30.6-0.6-0.8-0.70.6-0.7-0.8-0.1-0.50.0-0.4-0.8-0.60.3
Time in novel zone, hab. session 20.10.10.2-0.4-0.3-0.40.5-0.4-0.3-0.1-0.10.3-0.5-0.30.40.0
Total zone transitions, hab. session 20.40.51.00.80.90.9-0.81.00.8-0.20.0-0.40.60.90.6-0.4
Total locomotion distance, hab. session 20.10.10.20.40.40.4-0.40.50.2-0.0-0.2-0.20.30.40.2-0.1
Locomotion velocity, hab. session 20.10.20.40.50.50.5-0.50.60.40.0-0.1-0.30.50.50.1-0.1
Novel to familiar place preference ratio1.92.03.8-1.6-1.5-1.61.6-1.5-1.51.20.12.0-1.1-1.5-0.91.4
Novelty place preference1.61.72.7-1.5-1.4-1.51.5-1.4-1.51.00.11.7-1.0-1.4-0.81.2
Time in novel zone, NPP test1.51.63.1-1.4-1.3-1.41.4-1.3-1.31.20.31.8-0.9-1.3-0.81.3
Total zone transitions, NPP test0.10.10.30.20.30.3-0.20.30.0-0.2-0.4-0.10.00.30.6-0.2
Total locomotion distance, NPP test0.10.20.30.50.40.5-0.50.50.1-0.2-0.5-0.50.40.50.0-0.3
Locomotion velocity, NPP test0.10.10.80.0-0.1-0.00.0-0.0-0.4-0.3-0.9-0.20.1-0.1-0.2-0.2
Pavlov. Cond. lever latency0.20.21.5-0.1-0.2-0.20.0-0.2-0.20.50.4-0.00.2-0.2-1.20.6
Pavlov. Cond. magazine entry latency1.01.27.2-0.1-0.1-0.10.4-0.10.1-1.9-1.4-0.5-0.90.02.7-1.4
Pavlov. Cond. change in total contacts1.31.44.61.11.31.2-1.01.31.6-0.90.3-0.50.41.32.2-1.0
Pavlov. Cond. index score1.31.77.20.90.91.0-0.70.81.0-1.9-1.0-1.00.01.02.7-1.8
Pavlov. Cond. latency score0.91.15.00.70.80.8-0.60.70.8-1.5-0.8-0.80.00.82.2-1.5
Pavlov. Cond. lever contacts0.81.05.50.60.70.6-0.40.60.7-1.4-0.8-0.5-0.20.72.3-1.3
Pavlov. Cond. magazine entry number1.62.08.3-1.0-1.0-1.00.7-0.9-1.22.10.91.30.0-1.1-2.91.9
Pavlov. Cond. intertrial magazine entries0.40.41.2-0.6-0.6-0.60.5-0.5-0.40.90.50.6-0.4-0.6-0.81.1
Pavlov. Cond. lever-magazine prob. diff.1.62.08.91.11.21.2-0.91.11.3-1.9-0.8-1.00.11.33.0-1.8
Pavlov. Cond. response bias1.82.211.20.90.90.9-0.60.91.2-2.2-1.1-1.1-0.31.03.3-1.9
Bone: apparent density1.42.34.1-1.8-2.0-1.81.9-2.0-2.00.2-0.90.8-1.6-1.9-0.50.7
Bone surface0.20.30.7-0.3-0.6-0.30.3-0.8-0.6-0.6-0.8-0.7-0.4-0.5-0.2-0.5
Bone volume0.20.30.9-0.6-0.9-0.60.6-0.9-0.7-0.1-0.3-0.1-0.7-0.8-0.30.1
Bone: connectivity density1.92.94.9-1.9-2.1-1.92.1-2.2-2.2-0.2-1.61.2-2.1-1.90.40.3
Bone: cortical apparent density0.91.12.21.21.41.3-1.21.31.5-0.40.4-0.00.61.31.0-0.7
Bone: cortical area0.71.13.80.70.70.7-1.00.70.71.21.5-0.41.40.6-2.00.8
Bone: cortical porosity0.20.20.7-0.4-0.6-0.50.4-0.5-0.6-0.0-0.5-0.1-0.1-0.6-0.80.4
Bone: cortical porosity0.10.10.6-0.2-0.3-0.30.2-0.2-0.30.2-0.10.10.1-0.3-0.80.5
Bone: cortical thickness0.81.37.6-0.2-0.3-0.3-0.1-0.2-0.22.01.40.60.6-0.4-2.81.7
Bone: cortical thickness1.31.53.91.51.11.4-1.51.10.8-1.1-0.7-2.01.21.2-0.1-1.2
Bone: cortical tissue density1.01.22.41.21.41.4-1.31.41.5-0.50.4-0.10.61.41.2-0.8
Bone: elastic displacement2.12.44.3-1.7-2.1-2.01.8-1.8-1.70.5-0.60.9-1.5-2.0-1.01.4
Bone: elastic work0.81.01.8-1.1-1.3-1.31.1-1.2-1.00.5-0.10.6-1.0-1.3-0.71.1
Bone: endosteal estimation1.32.95.91.91.61.9-1.91.61.7-1.6-0.2-2.41.41.71.2-1.9
Bone: endosteal perimeter1.32.74.21.81.91.9-2.01.81.90.31.8-1.52.11.8-0.4-0.6
Bone: final force1.22.04.11.71.51.7-1.81.31.3-0.8-0.1-2.01.61.5-0.2-1.3
Bone: final moment1.11.83.71.61.31.6-1.81.31.2-0.6-0.0-1.91.61.4-0.3-1.1
Bone: marrow area1.42.96.21.91.61.9-1.91.51.6-1.8-0.3-2.51.31.71.3-2.0
Bone: maximum diameter0.81.53.31.31.21.3-1.51.21.10.61.3-1.11.81.2-1.4-0.0
Bone: maximum force1.01.83.61.61.41.6-1.71.21.3-0.70.2-1.91.51.50.0-1.2
Bone: maximum moment0.81.53.31.41.21.5-1.51.11.2-0.60.2-1.81.41.3-0.1-1.0
Bone: minimum diameter0.30.51.90.50.60.4-0.60.70.90.71.4-0.50.90.5-0.70.5
Bone: periosteal estimation0.91.83.81.61.41.6-1.81.31.4-0.40.6-2.01.71.4-0.5-0.8
Bone: periosteal perimeter1.22.04.01.31.41.4-1.61.31.41.01.9-1.22.01.3-1.70.2
Bone: post-yield work1.31.74.41.31.11.3-1.21.01.0-1.7-0.5-2.10.91.21.1-1.8
Bone: stiffness1.72.63.91.81.92.0-1.91.71.7-0.70.5-1.81.81.90.3-1.6
Bone: tissue strength0.10.10.4-0.2-0.1-0.10.2-0.1-0.10.40.10.6-0.2-0.10.10.3
Bone: trabecular number1.72.74.3-2.0-2.0-1.92.1-2.1-2.10.3-1.01.4-1.8-1.9-0.10.8
Bone: trabecular spacing0.20.30.70.70.50.7-0.80.60.60.20.3-0.60.60.6-0.50.2
Bone: trabecular thickness1.01.22.3-1.3-1.4-1.51.5-1.4-1.3-0.1-0.80.4-1.1-1.4-0.10.4
Bone: trabecular tissue density1.72.44.31.62.01.7-1.82.12.00.81.7-0.01.81.8-0.5-0.0
Breakpoint value in progressive ratio session0.40.51.60.70.60.5-0.40.5-0.1-0.9-1.3-0.80.60.50.4-1.1
Distance traveled before self-admin3.03.24.52.02.02.1-2.11.92.0-1.40.2-1.91.72.10.8-1.8
Distance traveled after self-admin2.62.95.61.82.12.0-2.01.92.4-0.60.8-1.31.72.10.7-1.4
Delta time in closed arm before/after self-admin0.40.41.1-0.8-0.7-0.91.0-0.8-0.50.10.10.6-0.7-0.70.2-0.0
Delta time in open arm before/after self-admin1.41.33.71.31.01.2-1.20.90.2-0.8-1.9-1.41.21.0-0.1-1.3
Diff in mean of infusions in LGA sessions0.30.41.9-0.4-0.6-0.60.5-0.1-0.80.5-0.10.3-0.2-0.7-0.71.4
Extinction: sum of active levers before priming2.22.38.21.11.01.2-1.00.4-0.4-1.1-2.4-2.01.81.0-0.9-2.9
Active lever presses in extinction session 60.20.20.80.50.30.3-0.30.40.3-0.5-0.9-0.70.40.30.3-0.4
Delta distance traveled before/after self-admin0.50.52.3-0.4-0.4-0.50.3-0.10.11.20.81.1-0.2-0.4-0.61.5
Delta ambulatory time before/after self-admin0.70.82.2-0.9-0.7-0.90.7-0.5-0.31.01.11.0-0.4-0.8-0.91.5
Time in closed arm before self-admin0.91.03.6-0.8-0.5-0.70.7-0.4-0.21.31.91.6-0.8-0.5-0.11.5
Time in closed arm after self-admin1.01.13.0-1.1-0.7-1.01.1-0.6-0.31.11.51.7-1.0-0.70.31.2
Time in open arm before self-admin0.20.20.8-0.0-0.3-0.2-0.1-0.20.8-0.20.9-0.9-0.2-0.3-0.10.4
Time in open arm after self-admin3.33.69.92.11.61.9-2.01.31.1-2.0-2.2-3.11.51.60.4-2.4
Sum of active levers in priming session hrs 5-61.81.83.71.41.21.3-1.21.10.8-1.7-1.0-1.70.91.21.2-1.9
Time to tail flick, vehicle, before self-admin0.80.83.00.30.30.3-0.40.80.21.70.91.20.60.4-0.81.6
Time to tail flick, vehicle, after self-admin3.53.85.8-2.0-1.9-2.12.2-1.9-2.42.1-0.62.3-0.9-2.0-2.11.8
Time to tail flick, test, before self-admin0.20.20.60.50.60.4-0.40.50.80.40.40.50.10.60.40.1
Time to tail flick, test, after self-admin3.23.37.1-1.8-1.6-1.81.7-1.4-1.42.50.92.7-0.9-1.6-1.92.4
Delta time to tail flick, vehicle, before/after SA5.35.29.3-2.6-2.6-2.82.9-2.9-3.00.9-1.41.7-1.7-2.7-1.71.0
Delta time to tail flick, test, before/after SA0.80.82.0-0.8-0.8-0.80.6-0.6-0.71.30.60.8-0.2-0.8-1.21.4
Ambulatory time before self-admin3.13.24.81.92.02.1-2.11.71.9-1.40.4-2.21.72.00.7-2.1
Ambulatory time after self-admin0.70.82.00.91.11.0-1.01.01.4-0.11.0-0.41.01.10.1-0.5
Total heroin consumption0.40.50.90.90.70.8-1.00.90.8-0.00.4-0.80.80.7-0.20.1
Area under the delay curve0.40.51.90.50.80.6-0.40.60.4-0.1-1.40.30.70.80.3-0.9
Delay disc. indifference point, 0s delay0.30.41.00.60.60.6-0.60.60.30.6-0.80.41.00.6-0.50.2
Delay disc. indifference point, 16s delay0.30.31.6-0.7-0.2-0.50.8-0.5-0.40.5-0.41.3-0.2-0.3-0.2-0.3
Delay disc. indifference point, 2s delay0.30.30.70.30.70.5-0.30.40.40.6-0.40.70.90.6-0.4-0.4
Delay disc. indifference point, 24s delay1.11.12.0-1.3-1.0-1.31.4-1.3-1.30.5-0.71.2-0.6-1.1-0.80.1
Delay disc. indifference point, 4s delay1.61.75.01.21.51.3-1.11.51.3-1.0-1.1-0.20.31.52.2-1.1
Delay disc. indifference point, 8s delay0.50.51.40.70.80.8-0.60.70.5-0.5-1.2-0.30.80.80.4-0.9
Delay discount exponential model param0.40.41.5-0.5-0.7-0.60.4-0.4-0.40.11.2-0.1-0.7-0.7-0.21.0
Delay discount hyperbolic model param0.50.51.4-0.6-0.8-0.70.5-0.6-0.50.31.20.0-0.7-0.8-0.31.0
Fecal boli incidents, locomotor time 11.01.15.00.30.50.5-0.20.1-0.7-1.4-2.1-1.10.50.40.8-2.2
Change in fecal boli incidents, locomotor task1.11.18.1-0.2-0.9-0.50.1-0.8-1.00.8-0.8-0.30.4-0.8-2.81.0
Time >=10cm from walls, locomotor time 10.30.31.4-0.1-0.20.1-0.2-0.2-0.6-0.50.4-1.20.2-0.2-1.1-0.4
Bouts of movement, locomotor time 10.30.31.1-0.6-0.2-0.30.7-0.4-0.6-0.7-0.40.3-0.4-0.20.9-1.1
Total resting periods, locomotor time 10.30.41.0-0.7-0.2-0.40.7-0.5-0.7-0.7-0.30.4-0.4-0.31.0-1.0
Rest time, locomotor task time 10.70.73.00.00.40.30.00.10.3-1.60.3-0.9-0.10.31.7-1.7
Distance moved, locomotor task time 10.50.51.40.50.40.5-0.70.70.31.20.60.30.60.4-1.11.1
Vertical activity count, locomotor time 10.80.92.80.30.50.3-0.50.80.71.70.91.50.50.4-0.61.7
Time >=10cm from walls, locomotor time 20.20.21.3-0.1-0.10.0-0.1-0.2-0.7-0.10.0-0.20.4-0.2-1.2-0.2
Bouts of movement, locomotor time 21.82.08.4-1.5-0.9-1.21.4-0.9-0.61.60.72.9-1.6-0.90.71.6
Total resting periods, locomotor time 21.51.67.5-1.3-0.7-1.01.3-0.6-0.51.30.62.7-1.6-0.71.11.4
Rest time, locomotor task time 20.50.63.9-0.3-0.1-0.30.6-0.3-0.5-1.1-0.1-0.1-1.0-0.12.0-0.9
Distance moved, locomotor task time 20.30.41.7-0.2-0.3-0.20.1-0.2-0.41.20.20.70.3-0.3-1.31.0
Vertical activity count, locomotor time 20.20.21.00.20.40.2-0.10.60.70.5-0.11.00.50.40.30.6
Weight adjusted by age0.80.92.01.31.01.3-1.41.20.8-0.5-0.1-1.10.71.10.3-0.5
Seeking ratio, delayed vs. immediate footshock2.73.14.7-1.9-1.8-1.91.9-2.1-2.21.4-1.71.6-0.9-1.9-2.00.9
Locomotion in novel chamber0.30.41.40.70.60.6-0.70.60.70.21.2-0.60.60.6-0.0-0.0
Locomotion in novel chamber post-restriction0.70.92.3-1.2-0.7-1.01.3-1.0-1.20.6-0.61.5-0.8-0.70.5-0.2
Progressive ratio0.40.40.9-0.8-0.6-0.70.7-0.6-0.80.2-1.00.9-0.7-0.60.20.3
Food seeking constrained by brief footshock0.50.61.3-0.8-0.9-0.90.9-0.6-0.7-0.10.30.5-1.1-0.80.70.8
Seeking ratio, punishment vs. effort0.10.10.6-0.0-0.2-0.20.2-0.20.0-0.60.7-0.8-0.1-0.20.0-0.1
Run reversals in cocaine runway, females2.62.67.61.51.41.4-1.72.12.40.42.8-0.00.51.51.51.3
Run reversals in cocaine runway, males0.60.62.3-0.4-0.1-0.30.40.10.60.91.21.5-0.5-0.10.81.1
Latency to leave start box in cocaine runway0.10.10.40.40.20.2-0.30.40.3-0.3-0.30.3-0.00.20.60.3
Latency to leave start box in cocaine runway, F0.20.21.20.30.00.1-0.10.20.2-0.6-1.1-0.1-0.20.10.6-0.0
Latency to leave start box in cocaine runway, M1.11.01.91.21.11.2-1.31.41.0-0.80.7-0.80.81.10.9-0.4
Cd content in liver1.21.43.71.20.81.1-1.10.90.9-1.6-1.3-1.90.71.00.8-1.3
Co content in liver1.72.05.21.61.31.6-1.71.31.2-1.3-0.2-2.31.41.4-0.1-1.4
Cu content in liver0.10.10.6-0.2-0.2-0.20.2-0.2-0.10.00.8-0.30.1-0.2-0.4-0.0
Fe content in liver0.70.93.3-0.9-0.4-0.70.7-0.6-0.41.41.31.8-0.3-0.6-0.60.9
K content in liver0.40.41.4-0.7-0.4-0.60.7-0.5-0.90.60.11.2-0.5-0.5-0.30.4
Mg content in liver0.40.40.9-0.7-0.7-0.70.7-0.8-0.9-0.0-0.50.4-0.6-0.7-0.20.0
Mn content in liver0.10.10.2-0.4-0.3-0.30.4-0.3-0.5-0.30.2-0.1-0.1-0.30.1-0.2
Na content in liver0.80.82.40.81.11.0-1.11.00.80.81.60.11.01.0-0.4-0.1
Rb content in liver0.81.01.5-1.1-1.2-1.21.2-1.1-1.10.7-0.30.9-0.7-1.2-1.01.0
Se content in liver0.50.62.6-0.8-0.4-0.60.6-0.6-0.70.91.60.8-0.1-0.6-0.90.5
Sr content in liver1.31.22.0-1.2-1.1-1.01.3-1.2-1.2-1.4-0.9-0.1-1.3-1.00.9-0.7
Zn content in liver0.50.51.9-0.0-0.3-0.10.2-0.3-0.5-1.4-1.2-1.1-0.3-0.20.6-0.9